CN210856087U - High-purity white blood cell extraction element - Google Patents

Abstract

The utility model discloses a high-purity white blood cell extraction element, including the erlenmeyer flask, the top of erlenmeyer flask cup joints mutually with the bottom of depositing the liquid pipe, it has the rubber circle to closely laminate between liquid pipe and the erlenmeyer flask, the bottom of depositing the liquid pipe is through a plurality of coupling mechanism and erlenmeyer flask looks rigid coupling, the top interference fit of depositing the liquid pipe has the top cap, the right-hand member of depositing the liquid pipe rigid coupling in proper order from top to bottom has three shutoff mechanism. This high-purity leucocyte extraction element, effect through the rubber circle, make the erlenmeyer flask and deposit and be connected between the liquid pipe and realize sealing, effect through the ejector pin, the top that makes the liquid pipe of depositing can be closed, effect through first chock, it is internal to make the cylinder can insert the pipe, thereby realize the extraction to the leucocyte, because the diameter of body is less than the erlenmeyer flask far, consequently, leucocyte layer after the layering can be more obvious, make the leucocyte be difficult for being infected with other substances when extracting, great increase the purity of leucocyte, facilitate for follow-up operation.

Description

High-purity white blood cell extraction element

Technical Field

The utility model relates to a high-purity white blood cell extraction element technical field specifically is a high-purity white blood cell extraction element.

Background

Leukocytes are a colorless, spherical, nucleated blood cell. The total number of normal adult leukocytes is (4.0-10.0) x109/L, and can be changed within a certain range due to different time of day and different functional states of the organism. Leukocytes are not a homogeneous cell population and can be classified into three major groups according to their morphology, function and origin: granulocytes, monocytes and lymphocytes, wherein granulocytes are classified into neutrophils, eosinophils and basophils according to the different staining properties of granules in cytoplasm. For the extraction of the white blood cells, a centrifugation mode is usually adopted to enable the blood to generate a layering phenomenon, however, the content of the white blood cells in the blood is relatively low, one side of the white blood cells is relatively thin after layering, and other cells are easily extracted during extraction, so that the purity of the extracted white blood cells is low, and the subsequent work is not facilitated.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a high-purity white blood cell extraction element to one side of the white blood cell that proposes in solving above-mentioned background art is relatively thin, very easily extracts for other cells when extracting, and the white blood cell purity that leads to extracting is lower, is unfavorable for the problem of follow-up work.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a high-purity white blood cell extraction element, includes the erlenmeyer flask, the top of erlenmeyer flask cup joints mutually with the bottom of depositing the liquid pipe, it has the rubber circle to closely laminate between liquid pipe and the erlenmeyer flask, the bottom of depositing the liquid pipe is through a plurality of coupling mechanisms and erlenmeyer flask looks rigid coupling, the top interference fit of depositing the liquid pipe has the top cap, the right-hand member of depositing the liquid pipe rigid coupling in proper order from top to bottom has three shutoff mechanism.

Preferably, the erlenmeyer flask includes bottle, ring channel, first rectangular channel and first pinhole, the ring channel has been seted up on the top of bottle, the ring channel cup joints with the bottom of depositing the liquid pipe mutually, the upper surface and the rubber circle of bottle laminate mutually, four first rectangular channels, four have evenly been seted up to the top lateral wall of bottle the first rectangular channel's bottom is all seted up horizontal first pinhole.

Preferably, the liquid storage pipe includes the body, keeps off ring, second rectangular channel, second pinhole and gets the liquid hole, the bottom and the ring channel of body cup joint mutually, the bottom and the rubber circle looks rigid coupling of body, the outer wall bottom and the fender ring integrated into one piece of body, four second rectangular channels, four have evenly been seted up to the outer wall that keeps off the ring the second pinhole has all been seted up on the top of second rectangular channel, the right-hand member of body has seted up three in proper order from top to bottom and has got the liquid hole, the below get the liquid hole and set up in the right-hand member position that keeps off the ring.

Preferably, coupling mechanism includes rectangular connection piece, first pin pole and second pin pole, the left side surface symmetry rigid coupling of rectangular connection piece has first pin pole and second pin pole, first pin pole and first pinhole interference fit, second pin pole and second pinhole interference fit, the both ends of rectangular connection piece respectively with first rectangular channel and second rectangular channel clearance fit.

Preferably, the top cap includes top cap body, handle, rubber buffer, the top rigid coupling of top cap body has the handle, the bottom rigid coupling of top cap body has the rubber buffer, the top interference fit of rubber buffer and body.

Preferably, the plugging mechanism comprises a stop block, an inner cavity, a first stop block, a second stop block and a pulling block, the stop block is in one-to-one correspondence with the liquid taking holes and fixedly connected with the pipe body, the inner cavity is formed in the stop block and the stop ring, the first stop block and the second stop block are in interference fit in the inner cavity, and the pulling block is fixedly connected to the right end of the second stop block.

Compared with the prior art, the beneficial effects of the utility model are that: this high-purity leucocyte extraction element, effect through the erlenmeyer flask, the depositing to centrifugation back lower floor's liquid has been realized, effect through coupling mechanism, make the erlenmeyer flask can with deposit liquid pipe looks rigid coupling, effect through the rubber circle, make the erlenmeyer flask and deposit and realize sealing up being connected between the liquid pipe, effect through the ejector pin, make the top of depositing the liquid pipe close, effect through first chock, it is internal to make the cylinder can insert the pipe, thereby realize the extraction to leucocyte, because the diameter of body is far less than the erlenmeyer flask, consequently, leucocyte layer after the layering can be more obvious, make the leucocyte be difficult for being infected with other substances when drawing, great increase the purity of leucocyte, facilitate for follow-up operation.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic diagram of the exploded structure of FIG. 1;

FIG. 3 is a schematic view of the rectangular connecting block and a second chock of FIG. 1;

fig. 4 is an enlarged schematic view of the connection mechanism of fig. 2.

In the figure: 1. the utility model provides a erlenmeyer flask, 101, the bottle, 102, the ring channel, 103, first rectangular channel, 104, first pinhole, 2, the liquid storage pipe, 201, the body, 202, keep off the ring, 203, second rectangular channel, 204, the second pinhole, 205, get the liquid hole, 3, coupling mechanism, 301, the rectangle connecting block, 302, first pin pole, 303, the second pin pole, 4, the top cap, 401, the top cap body, 402, the handle, 403, the rubber buffer, 5, the shutoff mechanism, 501, the dog, 502, the inner chamber, 503, first chock, 504, the second chock, 505, the pull block, 6, the rubber ring.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-4, the present invention provides a technical solution: the utility model provides a high-purity white blood cell extraction element, including erlenmeyer flask 1, the top of erlenmeyer flask 1 cup joints with the bottom of depositing liquid pipe 2 mutually, it has rubber circle 6 to closely laminate between depositing liquid pipe 2 and the erlenmeyer flask 1, rubber circle 6 plays sealed effect, the bottom of depositing liquid pipe 2 is through a plurality of coupling mechanism 3 and erlenmeyer flask 1 looks rigid coupling, the top interference fit of depositing liquid pipe 2 has top cap 4, top cap 4 makes the whole mechanism inside keep airtight, the right-hand member of depositing liquid pipe 2 rigid coupling has three shutoff mechanism 5 from top to bottom in proper order. The erlenmeyer flask 1 includes bottle 101, ring channel 102, first rectangular channel 103 and first pinhole 104, and ring channel 102 has been seted up on the top of bottle 101, and ring channel 102 cup joints with the bottom of depositing liquid pipe 2 mutually, and the upper surface and the rubber circle 6 of bottle 101 laminate mutually, and four first rectangular channels 103 have evenly been seted up to the top lateral wall of bottle 101, and horizontal first pinhole 104 has all been seted up to the bottom of four first rectangular channels 103.

Deposit liquid pipe 2 and include body 201, keep off ring 202, second rectangular channel 203, second pinhole 204 and get liquid hole 205, the bottom and the ring channel 102 of body 201 cup joint mutually, the bottom and the 6 looks rigid couplings of rubber circle of body 201, the outer wall bottom and the fender ring 202 integrated into one piece of body 201, four second rectangular channels 203 have evenly been seted up to the outer wall that keeps off ring 202, second pinhole 204 has all been seted up on the top of four second rectangular channels 203, the right-hand member of body 201 has been seted up three in proper order from top to bottom and has been got liquid hole 205, the leucocyte after the layering is taken out through getting liquid hole 205, the right-hand member position of keeping off ring 202 is seted up to liquid hole 205 in the below. The connecting mechanism 3 comprises a rectangular connecting block 301, a first pin rod 302 and a second pin rod 303, the outer surface of the left side of the rectangular connecting block 301 is symmetrically and fixedly connected with the first pin rod 302 and the second pin rod 303, the first pin rod 302 is in interference fit with the first pin hole 104, the second pin rod 303 is in interference fit with the second pin hole 204, and two ends of the rectangular connecting block 301 are in clearance fit with the first rectangular groove 103 and the second rectangular groove 203 respectively.

Top cap 4 includes top cap body 401, handle 402, rubber buffer 403, and top cap body 401's top rigid coupling has handle 402, and top cap body 401's bottom rigid coupling has rubber buffer 403, rubber buffer 403 and body 201's top interference fit, and rubber buffer 403 makes body 201's top interference fit. Plugging mechanism 5 includes dog 501, inner chamber 502, first chock 503, second chock 504 and draws piece 505, three dog 501 one-to-one gets liquid hole 205 and body 201 looks rigid coupling, the axis position processing of first chock 503 has the hole, first chock 503 glues with body 201 and fender ring 202, inner chamber 502 has all been seted up in dog 501 and the fender ring 202, interference fit has first chock 503 and second chock 504 in the inner chamber 502, the right-hand member rigid coupling of second chock 504 has draws piece 505, draw piece 505 can draw second chock 504 from keeping off ring 202.

Pulling the handle 402 to make the handle 402 drive the top cover body 401 to move upwards, so that the rubber plug 403 is separated from the top end of the tube body 201, injecting blood into the whole mechanism from the top end of the tube body 201 to make the liquid level close to the top end of the tube body 201, placing the whole mechanism into a centrifugal device to make the blood in the whole mechanism centrifugally stratify, making the stratified white blood cells be in the middle lower position of the tube body 201, because the diameter of the tube body 201 is far smaller than that of the conical flask 1, the stratified white blood cells are in higher stratification, pulling the pulling block 505 to make the pulling block 505 drive the second plugging block 504 to be separated from the baffle ring 202, inserting the needle head of the syringe into the inner hole of the first plugging block 503, making the needle head enter the tube body 201 through the first plugging block 503, pulling the syringe to draw the white blood cells in the tube body 201 into the syringe, so as to realize the extraction of the white blood cells, and adjusting the position of the needle head in the tube, thereby maximally pumping the white blood cells in the tube body 201 into the interior of the syringe to realize high-purity extraction of the white blood cells.

In the description of the present invention, it is to be understood that the terms "coaxial", "bottom", "one end", "top", "middle", "other end", "upper", "one side", "top", "inner", "front", "center", "both ends", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore, should not be construed as limiting the present invention.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "disposed," "connected," "fixed," "screwed" and the like are to be construed broadly, e.g., as meaning fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through an intermediate medium, and may be connected through the inside of two elements or in an interaction relationship between two elements, unless otherwise specifically defined, and the specific meaning of the above terms in the present invention will be understood by those skilled in the art according to specific situations.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. A high-purity white blood cell extraction device comprises a conical flask (1), and is characterized in that: the top of erlenmeyer flask (1) cup joints with the bottom of depositing liquid pipe (2) mutually, it has rubber circle (6) to closely laminate between liquid pipe (2) and erlenmeyer flask (1), the bottom of depositing liquid pipe (2) is through a plurality of coupling mechanism (3) and erlenmeyer flask (1) looks rigid coupling, the top interference fit of depositing liquid pipe (2) has top cap (4), the right-hand member of depositing liquid pipe (2) has three shutoff mechanism (5) from top to bottom rigid coupling in proper order.

2. The apparatus for extracting high purity leukocytes according to claim 1, wherein: the utility model discloses a taper bottle (1) is characterized in that the taper bottle (1) includes bottle (101), ring channel (102), first rectangular channel (103) and first pinhole (104), ring channel (102) have been seted up on the top of bottle (101), ring channel (102) cup joint with the bottom of depositing liquid pipe (2) mutually, the upper surface and the rubber circle (6) of bottle (101) are laminated mutually, four first rectangular channel (103), four have evenly been seted up to the top lateral wall of bottle (101) the bottom of first rectangular channel (103) has all been seted up horizontal first pinhole (104).

3. The apparatus for extracting high purity leukocytes according to claim 1, wherein: deposit liquid pipe (2) including body (201), fender ring (202), second rectangular channel (203), second pinhole (204) and get liquid hole (205), the bottom and ring channel (102) of body (201) cup joint mutually, the bottom and rubber circle (6) looks rigid coupling of body (201), the outer wall bottom and the fender ring (202) integrated into one piece of body (201), four second rectangular channels (203), four have evenly been seted up to the outer wall that keeps off ring (202) second pinhole (204) have all been seted up on the top of second rectangular channel (203), the right-hand member of body (201) has been seted up three from top to bottom in proper order and has been got liquid hole (205), the below get liquid hole (205) and set up in the right-hand member position that keeps off ring (202).

4. The apparatus for extracting high purity leukocytes according to claim 1, wherein: connecting mechanism (3) include rectangular connection piece (301), first pin pole (302) and second pin pole (303), the left side surface symmetry rigid coupling of rectangular connection piece (301) has first pin pole (302) and second pin pole (303), first pin pole (302) and first pinhole (104) interference fit, second pin pole (303) and second pinhole (204) interference fit, the both ends of rectangular connection piece (301) respectively with first rectangular channel (103) and second rectangular channel (203) clearance fit.

5. The apparatus for extracting high purity leukocytes according to claim 1, wherein: top cap (4) include top cap body (401), handle (402), rubber buffer (403), the top rigid coupling of top cap body (401) has handle (402), the bottom rigid coupling of top cap body (401) has rubber buffer (403), the top interference fit of rubber buffer (403) and body (201).

6. The apparatus for extracting high purity leukocytes according to claim 1, wherein: plugging mechanism (5) are including dog (501), inner chamber (502), first chock (503), second chock (504) and draw piece (505), three dog (501) one-to-one gets liquid hole (205) and body (201) looks rigid coupling, inner chamber (502) have all been seted up in dog (501) and fender ring (202), interference fit has first chock (503) and second chock (504) in inner chamber (502), the right-hand member rigid coupling of second chock (504) has draws piece (505).

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