CN209950076U - Experimental animal oxygen deficiency device - Google Patents
Experimental animal oxygen deficiency device Download PDFInfo
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- CN209950076U CN209950076U CN201920358100.XU CN201920358100U CN209950076U CN 209950076 U CN209950076 U CN 209950076U CN 201920358100 U CN201920358100 U CN 201920358100U CN 209950076 U CN209950076 U CN 209950076U
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Abstract
The utility model discloses an experimental animals oxygen deficiency device belongs to medical experimental apparatus technical field, including holding case, nitrogen cylinder and oxygen concentration detection instrument, the internally mounted who holds the case has the baffle, the hole has been seted up to the surface of baffle, hold the bottom of case and install the oxygen concentration probe. The utility model discloses when using, put into the object of many experiments and hold the check, open the governing valve this moment, nitrogen gas in the nitrogen cylinder passes through the trachea and carries to holding in the case, control holds the oxygen content of incasement, guide through oxygen concentration detection instrument and adjust the governing valve size, thereby stabilize nitrogen gas flow, current proof box compares, neotype experimental animals oxygen deficiency device is when using, can experiment many experimental objects simultaneously, it is more convenient to use, and oxygen content is unified, the error of experiment has been reduced, make the experimental result more accurate, the experimental animals of being convenient for do not carry out the oxygen deficiency operation according to the group.
Description
Technical Field
The utility model belongs to the technical field of medical experimental apparatus, specifically be an experimental animals oxygen deficiency device.
Background
Clinically, the occurrence and development of a plurality of diseases are closely related to hypoxia, an anoxic environment needs to be copied for experimental animals in the process of researching the pathogenesis of the diseases, the oxygen content and the temperature in the environment can be monitored in real time and accurately regulated, the environments of peripartum asphyxia and hypoxia of a newborn or a fetus are simulated and established, a model of cerebral anoxic damage is copied, and then a sample, protein and genes of an anoxic brain tissue are extracted to analyze the action and the molecular mechanism of the cerebral anoxic injury mechanism and related drug therapy in the anoxic ischemic encephalopathy, so that effective drug therapy is searched, and a certain experimental theoretical basis is provided for the development of new drugs.
At present, the oxygen deficiency device on the market structure is unreasonable, and the single can only carry out the oxygen deficiency experiment to an experimental animal, when doing the contrast experiment, needs many times to experiment, need control oxygen content between the experiment at every turn, and not only the operation is wasted time and energy, and the experimental error that brings is also great for the experimental result is not ideal.
SUMMERY OF THE UTILITY MODEL
The utility model aims to provide a: in order to solve the problems that the structure of an oxygen deficiency device on the market is unreasonable at present, oxygen deficiency experiments can be only carried out on one experimental animal at a time, when contrast experiments are carried out, multiple experiments are needed, oxygen content is required to be controlled between the experiments at each time, operation is time-consuming and labor-consuming, experimental errors caused by the operation are large, and experimental results are not ideal, the experimental animal oxygen deficiency device is provided.
The utility model adopts the technical scheme as follows: an experimental animal oxygen-lack device comprises a containing box, a nitrogen bottle and an oxygen concentration detector, wherein a partition plate is arranged in the containing box, the outer surface of the clapboard is provided with a hole, the bottom of the containing box is provided with an oxygen concentration probe, an air outlet is arranged at the rear side of the containing box, a hinge is rotatably connected above the containing box, a top plate is rotatably connected above the hinge, an adjusting valve is arranged at the air outlet end of the nitrogen cylinder, the air outlet end of the regulating valve is communicated with an air pipe, the air outlet end of the air pipe is communicated with the top plate, a gas adding buffer plate is arranged on the inner side of the top plate, a timer is arranged above the oxygen concentration detector, the oxygen concentration detector is electrically connected with a connecting wire, the connecting wire is connected with the oxygen concentration probe, the oxygen concentration detector, the timer and the oxygen concentration probe are electrically connected with an external power supply.
Wherein, the quantity of baffle is six at least, every equidistance distributes between the baffle, the baffle will hold the inside of case and divide into the cell, wherein the middle the cell is probe installation check, the cell of probe installation check both sides is the holding grid.
The oxygen concentration probe is positioned at the bottom of the probe mounting grid, and the gas addition buffer plate is positioned above the probe mounting grid.
Wherein, hold case and baffle and be transparent plastic material.
Wherein, tracheal end of giving vent to anger runs through the lower surface of roof, the top fixedly connected with slide bar of gaseous interpolation buffer board, slide bar sliding connection in the roof, the upper end fixedly connected with of slide bar props up the piece, the surface cover of slide bar is equipped with the spring.
The upper end and the lower end of the spring are respectively and fixedly connected to the supporting block and the top plate.
The number of the sliding rods, the springs and the support blocks is four, the four groups of the sliding rods, the springs and the support blocks are respectively located at four corners of the gas adding buffer plate, and the gas outlet end of the gas pipe is tightly attached to the upper surface of the gas adding buffer plate.
To sum up, owing to adopted above-mentioned technical scheme, the beneficial effects of the utility model are that: when the utility model is used, a plurality of experimental objects are put into the containing grid, then the top plate is covered, the regulating valve is opened at the moment, nitrogen in the nitrogen bottle is conveyed into the containing box through the air pipe to control the oxygen content in the containing box, secondly, the oxygen content in the containing box is measured by the oxygen concentration probe and is transmitted to the oxygen concentration detector, the size of the regulating valve is regulated by the oxygen concentration detector, thereby stabilizing the nitrogen flow, ensuring that the oxygen concentration in the containing box reaches the experimental requirement, and then completing the experiment by using the timer, compared with the existing test box, the novel experimental animal oxygen deficiency device can simultaneously perform the experiment on a plurality of experimental objects when in use, and is more convenient to use, and the oxygen content is uniform, so that the experimental error is reduced, the experimental result is more accurate, and the experimental animals can conveniently carry out anoxic operation according to groups.
Drawings
FIG. 1 is a schematic diagram of the structure of the present invention;
FIG. 2 is a schematic structural view of the containing box of the present invention;
fig. 3 is a schematic structural view of the buffer plate for adding gas in the present invention.
The labels in the figure are: 1. a nitrogen gas cylinder; 2. an oxygen concentration detector; 3. a timer; 4. a connecting wire; 5. an oxygen concentration probe; 6. a partition plate; 7. a hinge; 8. a top plate; 9. a gas addition buffer plate; 10. an air tube; 11. an air outlet; 12. a hole; 13. a probe mounting grid; 14. a holding grid; 15. a slide bar; 16. a spring; 17. supporting a block; 18. adjusting a valve; 19. a containing box.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the invention.
In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention; the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance; furthermore, unless expressly stated or limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, as they may be fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Referring to fig. 1-3, an experimental animal oxygen deficiency device comprises a containing box 19, a nitrogen bottle 1 and an oxygen concentration detector 2, wherein a partition plate 6 is installed inside the containing box 19, a hole 12 is formed in the outer surface of the partition plate 6, an oxygen concentration probe 5 is installed at the bottom of the containing box 19, an air outlet 11 is formed in the rear side of the containing box 19, a hinge 7 is rotatably connected above the containing box 19, a top plate 8 is rotatably connected above the hinge 7, an adjusting valve 18 is installed at the air outlet end of the nitrogen bottle 1, the air outlet end of the adjusting valve 18 is communicated with an air pipe 10, the air outlet end of the air pipe 10 is communicated with the top plate 8, a gas adding buffer plate 9 is installed on the inner side of the top plate 8, a timer 3 is installed above the oxygen concentration detector 2, the oxygen concentration detector 2 is electrically connected with a connecting wire 4, the timer 3 and the oxygen concentration probe 5 are both electrically connected with an external power supply, when the device is used, a plurality of experimental objects are placed into the containing grid 14, then the top plate 8 is covered, at the moment, the regulating valve 18 is opened, nitrogen in the nitrogen bottle 1 is conveyed into the containing box 19 through the air pipe 10, the oxygen content in the containing box 19 is controlled, secondly, the oxygen content in the containing box 19 is measured through the oxygen concentration probe 5, the oxygen content is conveyed into the oxygen concentration detector 2, the device guides the regulating valve 18 to be adjusted through the oxygen concentration detector 2, so as to stabilize the nitrogen flow, after the oxygen concentration in the containing box 19 reaches the experimental requirements, the timer 3 is used for timing and completing the experiment, compared with the existing test box, the novel experimental animal oxygen deficiency device can simultaneously carry out the experiment on a plurality of experimental objects when in use, and is more convenient to use, and the oxygen content is uniform, so that the experimental error is reduced, the experimental result is more accurate, and the experimental animals can conveniently carry out anoxic operation according to groups.
Further, the quantity of baffle 6 is six at least, equidistance distributes between every baffle 6, baffle 6 will hold 19 inside branch of case and become the cell, wherein the cell of middle most is probe installation check 13, the cell of probe installation check 13 both sides is holding check 14, as shown in fig. 2, when using, put into holding check 14 with the object of many experiments, can experiment many experimental objects simultaneously, it is more convenient to use, and oxygen content is unified, the error of experiment has been reduced, make the experimental result more accurate, the experimental animal of being convenient for carries out the oxygen deficiency operation according to the group respectively.
Further, oxygen concentration probe 5 is located the bottom of probe installation check 13, and gaseous buffer board 9 that adds is located the top of probe installation check 13, as shown in fig. 2, after covering roof 8, oxygen concentration probe 5 measures the oxygen content who holds in the case 19 this moment, and oxygen content conveys oxygen concentration detection instrument 2 in, and gaseous buffer board 9 that adds alleviates nitrogen gas supply in-process gas pressure power.
Further, hold case 19 and baffle 6 and be the transparent plastic material, as shown in fig. 1, when using, put into holding check 14 with the object of many experiments, the real-time status of experimental object is conveniently observed to the transparent plastic material, makes things convenient for going on of experiment.
Further, the end of giving vent to anger of trachea 10 runs through the lower surface of roof 8, the top fixedly connected with slide bar 15 of gaseous buffering board 9 that adds, slide bar 15 sliding connection is in roof 8, slide bar 15's upper end fixedly connected with prop up piece 17, slide bar 15's surface cover is equipped with spring 16, as shown in fig. 3, in the experiment, when pouring into nitrogen gas into, nitrogen gas is from the end blowout of giving vent to anger of trachea 10 this moment, nitrogen gas impact gas adds buffering board 9 this moment, gaseous buffering board 9 downstream that adds, spring 16 tightens up, thereby change nitrogen gas flow direction, play the effect of buffering.
Further, the upper and lower both ends of spring 16 are fixed connection in piece 17 and roof 8 respectively, as shown in fig. 3, during the experiment, when pouring into nitrogen gas, nitrogen gas was spout from the end of giving vent to anger of trachea 10 this moment, and nitrogen gas impact gas adds buffer board 9 this moment, and gas adds buffer board 9 downstream, and spring 16 tightens up to change the nitrogen gas flow direction, play the effect of buffering nitrogen gas.
Further, the quantity of slide bar 15, spring 16 and piece 17 is four, four groups of slide bars 15, spring 16 and piece 17 are located four corners of gaseous interpolation buffer board 9 respectively, the end of giving vent to anger of trachea 10 hugs closely in the upper surface of gaseous interpolation buffer board 9, as shown in fig. 3, in the experiment, when pouring into nitrogen gas into, nitrogen gas is from the end blowout of giving vent to anger of trachea 10 this moment, nitrogen gas impact gas at this moment adds buffer board 9, gaseous interpolation buffer board 9 downstream alleviates nitrogen gas supply in-process gas pressure.
The working principle is as follows: when the utility model is used, a plurality of experimental objects are put into the holding grid 14, then the top plate 8 is covered, the regulating valve 18 is opened at the moment, nitrogen in the nitrogen bottle 1 is conveyed into the holding box 19 through the air pipe 10 to control the oxygen content in the holding box 19, secondly, the oxygen content in the holding box 19 is measured through the oxygen concentration probe 5, the oxygen content is conveyed into the oxygen concentration detecting instrument 2, the experiment model regulates the size of the regulating valve 18 through the oxygen concentration detecting instrument 2 so as to stabilize the nitrogen flow, after the oxygen concentration in the holding box 19 reaches the experimental requirement, the experiment is timed by the timer 3, compared with the existing experimental box, the novel experimental animal oxygen deficiency device can simultaneously carry out the experiment on a plurality of experimental objects when in use, the use is more convenient, and the oxygen content is uniform, the experimental error is reduced, so that the experimental result is more accurate, is convenient for the experimental animals to carry out anoxic operation according to groups.
The above description is only exemplary of the present invention and should not be taken as limiting the scope of the present invention, as any modifications, equivalents, improvements and the like made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.
Claims (7)
1. The utility model provides an experimental animals oxygen deficiency device, is including holding case (19), nitrogen cylinder (1) and oxygen concentration detection instrument (2), its characterized in that: the oxygen concentration detector is characterized in that a partition board (6) is arranged inside the containing box (19), a hole (12) is formed in the outer surface of the partition board (6), an oxygen concentration probe (5) is installed at the bottom of the containing box (19), an air outlet (11) is formed in the rear side of the containing box (19), a hinge (7) is rotatably connected to the upper side of the containing box (19), a top plate (8) is rotatably connected to the upper side of the hinge (7), an adjusting valve (18) is installed at the air outlet end of the nitrogen gas bottle (1), an air outlet end of the adjusting valve (18) is communicated with an air pipe (10), the air outlet end of the air pipe (10) is communicated with the top plate (8), a gas adding buffer plate (9) is installed on the inner side of the top plate (8), a timer (3) is installed above the oxygen concentration detector (2), and the oxygen concentration detector (2) is, the connecting wire (4) is connected with the oxygen concentration probe (5), and the oxygen concentration detector (2), the timer (3) and the oxygen concentration probe (5) are all electrically connected with an external power supply.
2. The anoxic device for experimental animals according to claim 1, wherein: the quantity of baffle (6) is six at least, every equidistance distributes between baffle (6), baffle (6) will hold the inside of case (19) and divide into the cell, wherein the middle-most the cell is probe installation check (13), the cell of probe installation check (13) both sides is holding check (14).
3. The anoxic device for experimental animals according to claim 2, wherein: the oxygen concentration probe (5) is positioned at the bottom of the probe mounting grid (13), and the gas addition buffer plate (9) is positioned above the probe mounting grid (13).
4. The anoxic device for experimental animals according to claim 1, wherein: the containing box (19) and the partition plate (6) are made of transparent plastic materials.
5. The anoxic device for experimental animals according to claim 1, wherein: the end of giving vent to anger of trachea (10) runs through the lower surface of roof (8), top fixedly connected with slide bar (15) of gaseous interpolation buffer board (9), slide bar (15) sliding connection in roof (8), the upper end fixedly connected with of slide bar (15) props up piece (17), the surface cover of slide bar (15) is equipped with spring (16).
6. The anoxic device for experimental animals according to claim 5, wherein: the upper end and the lower end of the spring (16) are respectively and fixedly connected with the supporting block (17) and the top plate (8).
7. The anoxic device for experimental animals according to claim 5, wherein: the number of slide bar (15), spring (16) and a piece (17) is four, and four groups slide bar (15), spring (16) and a piece (17) are located respectively four corners of gas addition buffer board (9), the end of giving vent to anger of trachea (10) hug closely in the upper surface of gas addition buffer board (9).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920358100.XU CN209950076U (en) | 2019-03-21 | 2019-03-21 | Experimental animal oxygen deficiency device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920358100.XU CN209950076U (en) | 2019-03-21 | 2019-03-21 | Experimental animal oxygen deficiency device |
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| Publication Number | Publication Date |
|---|---|
| CN209950076U true CN209950076U (en) | 2020-01-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201920358100.XU Expired - Fee Related CN209950076U (en) | 2019-03-21 | 2019-03-21 | Experimental animal oxygen deficiency device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111685051A (en) * | 2020-07-01 | 2020-09-22 | 重庆医科大学 | Animal hypoxemia/reoxygenation culture apparatus |
| CN111699983A (en) * | 2020-06-12 | 2020-09-25 | 首都医科大学宣武医院 | Multifunctional mouse hypoxia experimental device |
-
2019
- 2019-03-21 CN CN201920358100.XU patent/CN209950076U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111699983A (en) * | 2020-06-12 | 2020-09-25 | 首都医科大学宣武医院 | Multifunctional mouse hypoxia experimental device |
| CN111685051A (en) * | 2020-07-01 | 2020-09-22 | 重庆医科大学 | Animal hypoxemia/reoxygenation culture apparatus |
| CN111685051B (en) * | 2020-07-01 | 2024-06-04 | 重庆医科大学 | Animal hypoxia/reoxygenation culture device |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200117 Termination date: 20210321 |
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| CF01 | Termination of patent right due to non-payment of annual fee |