CN209882898U

CN209882898U - Vitrification freezing straw

Info

Publication number: CN209882898U
Application number: CN201920131618.XU
Authority: CN
Inventors: 千日成
Original assignee: Individual
Current assignee: Aiersi Zhejiang Medical Technology Co ltd
Priority date: 2019-01-25
Filing date: 2019-01-25
Publication date: 2020-01-03
Anticipated expiration: 2029-01-25

Abstract

The utility model relates to a freezing straw of vitrification, including carrying pole and sleeve pipe, the intraductal portion of cover is equipped with stores the chamber, stores the chamber and is open structure in sheathed tube one end, carries the pole from preceding to back in proper order for carrying thing head end, connecting rod and shutoff handle, carries the thing head end and is equipped with and carries the thing groove, carries the thing groove and be blind groove structure, and connecting rod and shutoff handle junction form step-like end cap structure, carries the thing head end and the connecting rod of pole and can the suit and carry out the shutoff in the inside and through the shutoff handle of sheathed tube storage chamber to sheathed tube open end. The utility model discloses can realize carrying out closed low temperature to biomaterials such as oocyte or embryo and preserve, effectively avoid biomaterials such as oocyte or embryo and liquid nitrogen direct contact, be favorable to promoting the low temperature and preserve the effect, and simple structure, convenient to use.

Description

Vitrification freezing straw

Technical Field

The utility model belongs to the technical field of oocyte or embryo cryopreservation, in particular to a vitrification freezing straw.

Background

Cryopreservation of an oocyte or embryo refers to a preservation technique that inhibits its metabolic activity by low temperature conditions and preserves it for long periods without losing its biological activity. With the development of vitrification cryopreservation technology, cryopreservation of embryos and oocytes has been widely used clinically. At present, at least 85% of ova and at least more than 95% of embryos survive and develop after freezing and thawing, the utilization rate of the embryos is greatly improved, convenience is provided for the development of an assisted reproduction technology, and the preservation of female fertility becomes possible.

Most of the currently used freezing rods in clinical use are open cryopreservation rods, i.e. the oocytes and embryos are directly contacted with liquid nitrogen during the freezing and preservation process. Research shows that ionizing radiation generated by ozonolysis in liquid nitrogen can cause embryo DNA damage, has the risk of virus transmission and has potential harm to the embryo preserved by freezing. The closed freezing straw isolates the direct contact of the oocyte or embryo and the liquid nitrogen, the damage of the liquid nitrogen to the oocyte or embryo can be reduced, and the clinical application of the closed freezing straw becomes the future development trend. The existing closed type freezing carrying rod has relatively complex structure and relatively inconvenient use and operation, and can not achieve the expected effect on the preservation effect.

Disclosure of Invention

The utility model aims to solve the technical problem that a vitrification freezing wheat straw is provided can carry out closed cryo-preservation to biomaterials such as oocyte or embryo and avoid its and liquid nitrogen direct contact, promotes the cryo-preservation effect, simple structure, convenient to use.

The utility model provides a technical scheme that its technical problem adopted provides a freezing straw of vitrification, including carrying pole and sleeve pipe, the intraductal portion of cover is equipped with stores the chamber, it is open structure at sheathed tube one end to store the chamber, carry the pole from preceding to back in proper order for carrying thing head end, connecting rod and shutoff handle, it is equipped with year thing groove to carry the thing head end, it is blind groove structure to carry the thing groove, the connecting rod forms step-like end cap structure with shutoff handle junction, carry the thing head end and the connecting rod of pole and can adorn in the sheathed tube storage intracavity portion and carry out the shutoff through the shutoff handle to sheathed tube opening end.

The carrying head end is integrally of a semi-cylindrical structure, and the carrying groove is formed downwards along the plane of the semi-cylindrical structure.

The front end of the object carrying head end is of a smooth arc structure.

The connecting rod is from the front to the back for first connecting rod, transition connecting rod and second connecting rod in proper order, the transition connecting rod is from the front to the diameter expansion taper structure of back, the radial dimension of second connecting rod and the structure phase-match of storage chamber.

The plugging handle is of a cuboid structure.

The surface of the plugging handle is provided with anti-skid convex lines.

The carrying rod and the sleeve are made of the same material.

The sleeve pipe is the cuboid structure, it is cylindric cavity to store the chamber.

Advantageous effects

The utility model discloses in, biological material such as oocyte or embryo can bear in carrying the thing groove of carrying the pole front end, carries the pole front portion can adorn the cover and carry out the shutoff in the cover intraduct and through the shutoff handle that carries the pole to the realization carries out closed low temperature to biological material such as oocyte or embryo and preserves, effectively avoids biological material such as oocyte or embryo and liquid nitrogen direct contact, is favorable to promoting the low temperature and preserves the effect, and simple structure, convenient to use.

Drawings

Fig. 1 is a schematic structural diagram of the present invention.

Fig. 2 is a schematic view of the top view structure of the carrying rod of the present invention.

Fig. 3 is a schematic view of the structure of the carrier rod of the present invention.

Fig. 4 is a schematic front structural view of the carrying rod of the present invention.

Fig. 5 is a schematic structural diagram of the sleeve of the present invention.

Detailed Description

The present invention will be further described with reference to the following specific examples. It should be understood that these examples are for illustrative purposes only and are not intended to limit the scope of the present invention. Furthermore, it should be understood that various changes and modifications of the present invention may be made by those skilled in the art after reading the teachings of the present invention, and these equivalents also fall within the scope of the appended claims.

A vitrified frozen straw as shown in FIG. 1 comprises a carrying rod 1 and a sleeve 2.

As shown in fig. 5, the sleeve 2 is a cuboid structure, the storage cavity 3 is arranged inside the sleeve 2, the storage cavity 3 is a cylindrical cavity, and the storage cavity 3 is of an open structure at one end of the sleeve 2.

As shown in fig. 2-4, the carrying rod 1 comprises a carrying head end 4, a connecting rod 5 and a plugging handle 6 from front to back. The whole object carrying head end 4 is of a semi-cylindrical structure, and the front end of the object carrying head end 4 is of a smooth arc structure. Carry thing head end 4 and be equipped with and carry thing groove 7, carry thing groove 7 and set up downwards along the plane of half-cylindrical structure, and carry thing groove 7 and be blind groove structure for bear biological material such as oocyte or embryo. The connecting rod 5 is sequentially provided with a first connecting rod 5-1, a transition connecting rod 5-2 and a second connecting rod 5-3 from front to back. The transition connecting rod 5-2 is an expanding conical structure from front to back, and the radial dimension of the second connecting rod 5-3 is matched with the structure of the storage cavity 3. The plugging handle 6 is of a cuboid structure, a step-shaped plug structure is formed at the joint of the connecting rod 5 and the plugging handle 6, and anti-skid convex patterns 8 are arranged on the surface of the plugging handle 6.

As shown in fig. 1, the loading head end 4 of the loading rod 1 and the connecting rod 5 can be inserted into the storage chamber 3 of the casing 2 and the open end of the casing 2 can be plugged by the plugging handle 6. The carrying rod 1 and the sleeve 2 are made of the same material, have the same expansion coefficient, can be always kept closed in the normal temperature, the cooling process, the low-temperature storage period and the unfreezing process, and ensure that the oocyte and the embryo are not directly contacted with liquid nitrogen during the storage period of the oocyte and the embryo in the liquid nitrogen.

The application steps of the vitrified frozen straw are as follows:

(1) two ova or embryos of a glass suction tube are placed in a carrying groove 7 at the front end of a carrying rod 1, and vitrified refrigerating fluid (about 1 microliter) is reduced as much as possible;

(2) slowly inserting the rod 1 into the cannula 2, taking care that care needs to be taken during insertion to avoid ejecting the ovum or embryo;

(3) confirming that the carrying rod 1 and the sleeve 2 of the frozen straw are mutually inserted tightly, paying attention to careful operation, the ovum and the embryo are not frozen, if the operation has a vibration phenomenon, the ovum or the embryo is possibly shaken off and lost, and when the ovum or the embryo is unfrozen, the bad result that the ovum or the embryo cannot be retrieved is possibly caused;

(4) gently inserting the frozen straw into liquid nitrogen at an angle of 45 degrees, standing for 30 seconds, and then putting into the liquid nitrogen;

(5) the frozen straws were transferred to a liquid nitrogen storage tank for storage.

Claims

1. A vitrification freezing straw, including carrying pole (1) and sleeve pipe (2), its characterized in that: casing pipe (2) inside is equipped with stores chamber (3), store chamber (3) and be open structure in the one end of casing pipe (2), carry pole (1) from the front to back in proper order for carrying thing head end (4), connecting rod (5) and shutoff handle (6), it is equipped with year thing groove (7) to carry thing head end (4), it is blind groove structure to carry thing groove (7), connecting rod (5) and shutoff handle (6) junction form step type end cap structure, carry thing head end (4) and connecting rod (5) of pole (1) can the suit in storage chamber (3) inside of casing pipe (2) and carry out the shutoff through shutoff handle (6) to the open end of casing pipe (2).

2. A vitrified frozen straw as defined in claim 1, wherein: the carrying head end (4) is integrally of a semi-cylindrical structure, and the carrying groove (7) is formed downwards along the plane of the semi-cylindrical structure.

3. A vitrified frozen straw according to claim 1 or 2, characterized in that: the front end of the object carrying head end (4) is of a smooth arc structure.

4. A vitrified frozen straw as defined in claim 1, wherein: the connecting rod (5) is sequentially provided with a first connecting rod (5-1), a transition connecting rod (5-2) and a second connecting rod (5-3) from front to back, the transition connecting rod (5-2) is of an expanding cone-shaped structure from front to back, and the radial size of the second connecting rod (5-3) is matched with the structure of the storage cavity (3).

5. A vitrified frozen straw as defined in claim 1, wherein: the plugging handle (6) is of a cuboid structure.

6. A vitrified frozen straw according to claim 1 or 5, wherein: the surface of the plugging handle (6) is provided with anti-skid convex patterns (8).

7. A vitrified frozen straw as defined in claim 1, wherein: the carrying rod (1) and the sleeve (2) are made of the same material.

8. A vitrified frozen straw as defined in claim 1, wherein: the sleeve (2) is of a cuboid structure, and the storage cavity (3) is a cylindrical cavity.