CN210382389U - Dual-purpose vitrification freezing loading rod - Google Patents
Dual-purpose vitrification freezing loading rod Download PDFInfo
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- CN210382389U CN210382389U CN202020214109.6U CN202020214109U CN210382389U CN 210382389 U CN210382389 U CN 210382389U CN 202020214109 U CN202020214109 U CN 202020214109U CN 210382389 U CN210382389 U CN 210382389U
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Abstract
The utility model belongs to the technical field of biomedicine, a pole is carried in freezing of dual-purpose vitrification is specifically disclosed. The carrying rod comprises a sleeve with two open ends, a counterweight body arranged in the lower layer of the sleeve, an embryo placing rod arranged in the upper layer of the sleeve and a handle; the counterweight body comprises a metal column and an anti-slip sleeve fixedly surrounding the outer side surface of the metal column, and grooves are uniformly formed in the outer side surface of the anti-slip sleeve; the embryo placing rod comprises a carrying end, a placing connecting rod and an inserting end which are sequentially and integrally connected, and the carrying end is provided with a carrying groove; the handle comprises a connecting rod and a plugging handle which are sequentially and integrally connected, and a step-shaped plug structure is formed at the connecting part of the connecting rod and the plugging handle; when the device is used as an open type carrying rod, the handle is simultaneously inserted with the embryo placing rod and the sleeve; when the sealed type carrying rod is used, the openings at the two ends of the sleeve are sealed. The freezing carrying rod is simple in structure, can be selected to be used in an open type or a closed type according to needs, can avoid carrying the rod to float, and is flexible and convenient to use.
Description
[ technical field ] A method for producing a semiconductor device
The utility model belongs to the technical field of biomedicine, in particular to dual-purpose vitrification freezing carries pole.
[ background of the invention ]
The freezing technology of the ovum and the embryo is an important technical link for assisted reproduction, and the survival rate of the frozen ovum/embryo after thawing plays an important role in the success of transplantation. Currently, the vitrification freezing technique is used more and more extensively in the preservation of eggs and embryos, in which the embryos and eggs are brought into direct contact with liquid nitrogen to rapidly cool the embryos for less than 1 second, during which a glassy solid, rather than ice crystals, forms between the embryo and the surrounding liquid. The vitrification freezing of human ovum and embryo has the advantages of high survival rate after thawing, high pregnancy rate and high implantation rate after transplantation.
Since the key to vitrification is fast freezing, it is required that the ovum and embryo should be frozen and preserved by placing them on a special carrier and directly contacting with liquid nitrogen. However, sometimes the open carrier with the ovum and embryo directly contacting with liquid nitrogen may have cross contamination of the ovum and embryo with other embryo with virus or bacteria during the cryopreservation process, so a completely closed carrier is needed for the cryopreservation of the ovum/embryo. That is, depending on clinical needs, it is sometimes necessary to use an open type frozen carrier, and sometimes it is necessary to use a closed type frozen carrier.
The prior embryo vitrification freezing carrier is basically in a pure open type or a pure closed type, can not be selected to be used in an open type or a closed type according to actual requirements, and has the problem of inflexible use. For example, the chinese utility model CN 209882898U vitrified frozen straw is plugged by a plugging handle to realize the closed type of the carrier, which cannot be used as an open type or a semi-closed type and has the problem of floating straw; the Chinese utility model CN 208159973U is a novel closed vitrification freezing carrying rod which can only be used as a pure closed carrier and can solve the problem of floating of the carrier, but has the problems that the metal column can not be effectively fixed in the outer sleeve, an isolation tube is needed to be added to improve the sealing effect, and the structure is complicated; and Chinese new patent CN 203913154U biomaterial vitrification cryopreservation carrier, which is tightly connected with the sheath through the inserted link main body, thereby achieving the purpose that the biomaterial is reliably sealed in the cryopreservation carrier, and can only be used as a pure closed carrier, and has the problems that the operation of freezing carrier injection is troublesome and time-consuming.
[ Utility model ] content
In order to overcome the defects of the prior art, the utility model aims to provide a pole is carried in freezing of dual-purpose vitrification, this freezing pole simple structure that carries can select as required as open or closed use and can effectively avoid carrying the pole showy, and it is nimble convenient to use, and the practicality is strong.
In order to achieve the above purpose, the utility model adopts the technical proposal that:
a dual-purpose vitrification freezing carrying rod comprises a sleeve with two open ends, a counterweight body, an embryo placing rod and a handle, wherein the counterweight body is fixedly arranged in the lower layer of the sleeve, and the embryo placing rod is arranged in the upper middle layer of the sleeve; the counterweight body comprises a metal column and an anti-slip sleeve fixedly surrounding the outer side surface of the metal column, grooves are uniformly formed in the outer side surface of the anti-slip sleeve and penetrate through two end surfaces of the anti-slip sleeve, and the lower end of the sleeve is communicated with the upper end of the sleeve through the grooves; the embryo placing rod comprises a carrying end, a placing connecting rod and an inserting end which are integrally connected from bottom to top, and the carrying end is provided with a carrying groove; the handle comprises a connecting rod and a plugging handle which are sequentially and integrally connected from bottom to top, the connecting part of the connecting rod and the plugging handle forms a step-shaped plug structure, the insertion end can be inserted into the connecting rod, and the connecting rod can be sleeved in the sleeve and can plug the upper end opening of the sleeve through the plugging handle; when the device is used as an open type carrying rod, the handle is simultaneously inserted with the embryo placing rod and the sleeve; when the sealed type carrying rod is used, the openings at the two ends of the sleeve are sealed.
Furthermore, the carrying end is in a circular truncated cone shape, and the small-diameter end is a free end; the inserting end is cylindrical, and the end part of the inserting end is arc-shaped.
Furthermore, the connecting rod comprises a first connecting rod, a transition connecting rod and a connecting insertion pipe which are sequentially and integrally connected from top to bottom, the outer diameter of the first connecting rod is matched with the inner diameter of the sleeve, the transition connecting rod is in a round table shape, the small-diameter end of the transition connecting rod is connected with the connecting insertion pipe, and the inner diameter of the connecting insertion pipe is matched with the maximum outer diameter of the insertion end.
Further, the length of the counterweight body is 0.6-0.8cm, the anti-skid sleeve is made of rubber or sponge, and the metal column is made of copper and has the outer diameter of 2.0-2.1 mm.
Furthermore, the length of the sleeve is 11-13cm, the outer diameter is 2.8-3.0mm, and the inner diameter is 2.4-2.6 mm.
Furthermore, the length of the embryo placing rod is 5.5cm, the length of the carrying end is 1.2cm, the width of the carrying groove is 1-1.6mm, the depth of the carrying groove is 0.2-0.3mm, and the length of the splicing end is 5mm and the diameter of the splicing end is 1 mm.
Owing to used the technical scheme of the utility model, the utility model discloses following beneficial effect has:
1. the utility model discloses a dual-purpose vitrification freezing carries pole is a vitrification freezing device that can both seal and open the embryo of freezing animal and people. When the openings at the two ends of the sleeve are sealed, the embryo/ovum can not be in direct contact with liquid nitrogen in the freezing and storing processes, so that the phenomenon of mutual infection of the embryo/ovum and pathogens is avoided; and when only the head end of the sleeve is blocked by adopting the handle, the embryo/ovum can be directly contacted with liquid nitrogen in the freezing and preservation processes so as to ensure the survival after the freezing recovery. Namely, the user can select to adopt open type or closed type to carry out vitrification freezing preservation to embryo/ovum according to actual need, the flexibility is strong, the operation is convenient, simultaneously, its simple structure, easy processing to reduce manufacturing cost, provide the prerequisite for popularizing the vitrification freezing of using the embryo.
2. Very smooth to the inside pipe wall, if directly place the metal rod in the cover intraductally, there is the unable stable problem of placing in the cover intraductally of metal rod, the utility model discloses a counterweight body has wrapped up one deck antiskid cover outside the metal rod to effectively increased the frictional force between counterweight body and the sleeve pipe, make that counterweight body can be stable fix in sheathed tube lower floor, and then not only effectively promoted and carried the pole and sink the stability of placing in the liquid nitrogen, can place the pole to the embryo and play the supporting role moreover. In addition, through set up the recess that runs through two terminal surfaces of antiskid cover in the side of antiskid cover for when using as open, liquid nitrogen can be through this recess entering sleeve intraductal and with embryo direct contact.
[ description of the drawings ]
Fig. 1 is a schematic structural view of the dual-purpose vitrification freezing bar of the present invention used in an open type.
Fig. 2 is a schematic structural view of the dual-purpose vitrification freezing carrying rod of the present invention used in a closed type.
Fig. 3 is a schematic view of the structure of the handle of fig. 1.
FIG. 4 is a schematic view of the structure of the embryo placement rod of FIG. 1 or FIG. 2.
Fig. 5 is a schematic structural view of the weight body in fig. 1 or fig. 2.
The main reference symbols in the drawings are as follows:
in the figure, 1-sleeve, 2-counterweight body, 21-metal column, 22-antiskid sleeve, 221-groove, 3-embryo placing rod, 31-carrying end, 311-carrying groove, 32-placing connecting rod, 33-inserting end, 4-handle, 41-plugging handle, 42-connecting rod, 421-first connecting rod, 422-transition connecting rod and 423-connecting cannula.
The following detailed description of the invention will be further described in conjunction with the above-identified drawings.
[ detailed description ] embodiments
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
As shown in fig. 1, in a preferred embodiment of the present invention, a dual-purpose vitrification freezing carrying rod comprises a sleeve 1 with two open ends, a weight body 2, an embryo placing rod 3 and a handle 4, wherein the weight body 2 is fixedly placed in the lower layer of the sleeve 1 for increasing the weight of the carrying rod and sinking, so as to avoid the floating phenomenon of the carrying rod, thereby improving the freezing effect of the embryo and simultaneously playing a role of supporting the embryo placing rod 3; the embryo placing rod 3 is placed in the middle upper layer of the sleeve 1 and is used for placing embryo/ovum materials for freezing; the handle 4 can be simultaneously inserted with the embryo placing rod 3 and the sleeve 1. Wherein the length of the sleeve 1 is 11-13cm, the outer diameter is 2.8-3.0mm, the inner diameter is 2.4-2.6mm, the length of the counterweight body 2 is 0.6-0.8cm, and the embryo placing rod 3 is formed by injection molding of transparent plastics and has the length of 5.5 cm.
With continued reference to fig. 5, the outer diameter of the weight body 2 matches the inner diameter of the casing 1, and it includes a metal post 21 made of copper and having an outer diameter of 2.0-2.1mm and an anti-slip sleeve 22 made of sponge/rubber fixedly surrounding the outer side surface of the metal post 21, the anti-slip sleeve 22 effectively increases the friction force between the weight body 2 and the inner wall of the casing 1, so that the weight body 2 can be stably fixed in the casing 1; the outer side surface of the anti-slip sleeve 22 is uniformly provided with grooves 221, the grooves 221 penetrate through two end faces of the anti-slip sleeve 22, the lower end of the sleeve 1 is communicated with the upper end of the sleeve 1 through the grooves 221, and therefore when the carrying rod is used in an open mode, liquid nitrogen can enter the sleeve 1 from the grooves 221 and directly contact with embryos.
With reference to fig. 4, the embryo placing rod 3 comprises a carrying end 31, a placing connecting rod 32 and a splicing end 33 which are integrally connected from bottom to top, the carrying end 31 is in a shape of a truncated cone with a length of 1.2cm and a small-diameter end thereof is a free end, the carrying end 31 is provided with a carrying groove 311 with a width of 1-1.6mm and a depth of 0.2-0.3mm, and is used for placing embryos/ova and avoiding the phenomenon that the embryos or the ova are lost due to collision between the embryo placing rod 3 and the sleeve 1; the inserting end 33 is cylindrical with the length of 5mm and the diameter of 1mm, and the end part of the inserting end is arc-shaped.
Continuing to refer to fig. 3, the handle 4 includes a connecting rod 42 and a plugging handle 41 which are integrally connected from bottom to top, a connecting position of the connecting rod 42 and the plugging handle 41 forms a step-shaped plug structure, the insertion end 33 can be inserted into the connecting rod 42, the connecting rod 42 can be sleeved in the casing 1 and plugs an upper end opening of the casing 1 through the plugging handle 41; the connecting rod 42 comprises a first connecting rod 421, a transition connecting rod 422 and a connecting insertion tube 423 which are sequentially and integrally connected from top to bottom, the outer diameter of the first connecting rod 421 is matched with the inner diameter of the sleeve 1 so as to be capable of being just and stably inserted into the sleeve 1, the transition connecting rod 422 is in a circular truncated cone shape and has a small diameter end connected with the connecting insertion tube 423, the inner diameter of the connecting insertion tube 423 is matched with the maximum outer diameter of the insertion end 33, and therefore the insertion end 33 can be just and stably inserted into the connecting insertion tube 423.
As shown in fig. 1, when used as an open carrier bar: before freezing, the embryo placing rod 3 and the handle 4 are connected together by inserting the inserting end 33 into the connecting inserting pipe 423, and embryo information is printed or written on the plugging handle 41; during freezing, an embryo or an ovum is placed in the object carrying groove 311, then the embryo placing rod 3 and the connecting rod 42 are inserted into the sleeve 1 in liquid nitrogen, so that the upper end opening of the sleeve 1 is blocked by the blocking handle 41, at the moment, under the action of the counterweight body 2, the carrying rod is in an upright vertical state, and the liquid nitrogen passes through the groove 221 and is directly contacted with the embryo/ovum; when unfreezing, the handle 4 and the embryo placing rod 3 are directly taken out of the sleeve 1 together, and then the object carrying end 311 is placed in unfreezing liquid.
As shown in fig. 2, when used as a closed carrier bar: firstly, heating and sealing the lower end opening of the sleeve 1 by using a heat sealing machine, then placing an embryo or an ovum in the object carrying groove 311, directly and lightly inserting the embryo placing rod 3 into the sleeve 1 precooled on liquid nitrogen steam, and finally heating and sealing the upper end opening of the sleeve 1 by using the heat sealing machine and placing the sleeve into liquid nitrogen; when unfreezing, the upper end seal of the sleeve 1 is cut off by scissors, the handle 4 is lightly inserted into the sleeve to enable the connecting insertion tube 423 to be connected with the insertion end 33, the handle 4 and the embryo placing rod 3 are taken out of the sleeve 1 together (the operation needs to be carried out under the condition that at least one half of the protecting straw is in liquid nitrogen), and finally the carrying end 33 is put into the unfreezing liquid.
In conclusion, the utility model has simple structure and easy processing, thereby reducing the production cost; and the user can selectively adopt an open type or a closed type to carry out vitrification freezing preservation on the embryo/ovum according to actual needs, the flexibility is strong, the operation is convenient, meanwhile, the carrying rod can be kept in a sinking and upright state in liquid nitrogen, and the practicability is strong.
Claims (6)
1. The utility model provides a pole is carried in freezing of dual-purpose vitrification, includes that open sleeve pipe in both ends, the counter weight body, embryo place pole and handle, its characterized in that: the counterweight body is fixedly arranged in the lower layer of the sleeve, and the embryo placing rod is arranged in the upper middle layer of the sleeve; the counterweight body comprises a metal column and an anti-slip sleeve fixedly surrounding the outer side surface of the metal column, grooves are uniformly formed in the outer side surface of the anti-slip sleeve and penetrate through two end surfaces of the anti-slip sleeve, and the lower end of the sleeve is communicated with the upper end of the sleeve through the grooves; the embryo placing rod comprises a carrying end, a placing connecting rod and an inserting end which are integrally connected from bottom to top, and the carrying end is provided with a carrying groove; the handle comprises a connecting rod and a plugging handle which are sequentially and integrally connected from bottom to top, the connecting part of the connecting rod and the plugging handle forms a step-shaped plug structure, the insertion end can be inserted into the connecting rod, and the connecting rod can be sleeved in the sleeve and can plug the upper end opening of the sleeve through the plugging handle; when the device is used as an open type carrying rod, the handle is simultaneously inserted with the embryo placing rod and the sleeve; when the sealed type carrying rod is used, the openings at the two ends of the sleeve are sealed.
2. The dual-purpose vitrification freezing bar of claim 1 wherein: the object carrying end is in a circular truncated cone shape, and the small-diameter end of the object carrying end is a free end; the inserting end is cylindrical, and the end part of the inserting end is arc-shaped.
3. The dual-purpose vitrification freezing bar of claim 1 wherein: the connecting rod comprises a first connecting rod, a transition connecting rod and a connecting insertion pipe which are sequentially and integrally connected from top to bottom, the outer diameter of the first connecting rod is matched with the inner diameter of the sleeve, the transition connecting rod is in a round table shape, the small-diameter end of the transition connecting rod is connected with the connecting insertion pipe, and the inner diameter of the connecting insertion pipe is matched with the maximum outer diameter of the insertion end.
4. The dual-purpose vitrification freezing bar of claim 1 wherein: the length of the counterweight body is 0.6-0.8cm, the anti-skid sleeve is made of rubber or sponge, and the metal column is made of copper and has the outer diameter of 2.0-2.1 mm.
5. The dual-purpose vitrification freezing bar of claim 1 wherein: the length of the sleeve is 11-13cm, the outer diameter is 2.8-3.0mm, and the inner diameter is 2.4-2.6 mm.
6. The dual-purpose vitrification freezing bar of claim 1 wherein: the length of the embryo placing rod is 5.5cm, the length of the object carrying end is 1.2cm, the width of the object carrying groove is 1-1.6mm, the depth of the object carrying groove is 0.2-0.3mm, and the length of the insertion end is 5mm and the diameter of the insertion end is 1 mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020214109.6U CN210382389U (en) | 2020-02-26 | 2020-02-26 | Dual-purpose vitrification freezing loading rod |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020214109.6U CN210382389U (en) | 2020-02-26 | 2020-02-26 | Dual-purpose vitrification freezing loading rod |
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| CN210382389U true CN210382389U (en) | 2020-04-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202020214109.6U Active CN210382389U (en) | 2020-02-26 | 2020-02-26 | Dual-purpose vitrification freezing loading rod |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113412832A (en) * | 2020-12-30 | 2021-09-21 | 上海明悦医疗科技有限公司 | Freezing carrying rod and manufacturing method thereof |
| CN115486437A (en) * | 2021-06-18 | 2022-12-20 | 上海明悦医疗科技有限公司 | Auxiliary reproduction carrier bar assembly |
-
2020
- 2020-02-26 CN CN202020214109.6U patent/CN210382389U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113412832A (en) * | 2020-12-30 | 2021-09-21 | 上海明悦医疗科技有限公司 | Freezing carrying rod and manufacturing method thereof |
| CN115486437A (en) * | 2021-06-18 | 2022-12-20 | 上海明悦医疗科技有限公司 | Auxiliary reproduction carrier bar assembly |
| CN115486437B (en) * | 2021-06-18 | 2024-01-23 | 上海明悦医疗科技有限公司 | Auxiliary reproduction carrying rod assembly |
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