CN209231069U - All-in-one machine is dyed in workbench and film-making with the workbench - Google Patents
All-in-one machine is dyed in workbench and film-making with the workbench Download PDFInfo
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- CN209231069U CN209231069U CN201821792057.XU CN201821792057U CN209231069U CN 209231069 U CN209231069 U CN 209231069U CN 201821792057 U CN201821792057 U CN 201821792057U CN 209231069 U CN209231069 U CN 209231069U
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- suction nozzle
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Abstract
The utility model discloses a kind of workbench and all-in-one machine is dyed in the film-making with the workbench, it includes rack that all-in-one machine is dyed in film-making, manipulator, mechanical arm drive mechanism and workbench, the manipulator, the mechanical arm drive mechanism and the workbench are located in the rack, the mechanical arm drive mechanism is connected with the manipulator, the manipulator is located above the workbench, workbench includes sample placement section, suction nozzle placement section, dye liquor placement section and film-making dyeing portion, the film-making dyeing part is in one end of the dye liquor placement section and sample placement section, and the dye liquor placement section is between the suction nozzle placement section and film-making dyeing portion, the sample placement section is located at the side of dye liquor placement section, the layout of its workbench is relatively reasonable, the stroke of manipulator is on the basis of optimal shortest and can prevent each on workbench Cross contamination between region.
Description
Technical field
The utility model relates to medical field of biotechnology, more specifically, being a kind of workbench and having a workbench
Film-making dye all-in-one machine.
Background technique
When carrying out disorder in screening and diagnosis using tissue, for the ease of the observation and research to tissue, in research tissue
Before, it usually needs film-making dyeing is carried out to tissue, all-in-one machine is dyed in existing film-making, and the workbench of all-in-one machine is dyed in film-making
It is laid out unreasonable, causes the stroke of the manipulator of dyeing machine too long, and each on workbench in film-making dyeing course
There can be cross contamination between region.
Summary of the invention
The purpose of this utility model is to provide a kind of workbench and all-in-one machine, the work are dyed in the film-making with the workbench
The layout for making platform is relatively reasonable, on the basis of optimal shortest and can prevent each on workbench in the stroke for guaranteeing manipulator
Cross contamination between region.
Its technical solution is as follows:
Workbench, including sample placement section, suction nozzle placement section, dye liquor placement section and film-making dyeing portion, the film-making dyeing
Portion is located at one end of the dye liquor placement section and sample placement section, and the dye liquor placement section is located at the suction nozzle placement section and system
Between piece dyeing portion, the sample placement section is located at the side of dye liquor placement section.
Waste liquid placement section is additionally provided on the workbench, the waste liquid placement section is located at the suction nozzle placement section and the dye
Between liquid placement section.
The suction nozzle placement section includes suction nozzle frame and suction nozzle recycling box, and the suction nozzle recycling box is located at the one of the suction nozzle frame
Side, and the suction nozzle recycling box is located at one end of the sample placement section, the suction nozzle recycling box and film-making dyeing portion phase
It is right.
Workbench, including sample placement section, suction nozzle placement section, dye liquor placement section and film-making dyeing portion, the film-making dyeing
Portion is located at one end of the dye liquor placement section and the suction nozzle placement section, the dye liquor placement section be located at the sample placement section and
Between film-making dyeing portion, the suction nozzle placement section is located at the side of the sample placement section.
Waste liquid placement section is additionally provided on the workbench, the waste liquid placement section is located at the suction nozzle placement section and the system
Between piece dyeing portion.
The suction nozzle placement section includes suction nozzle frame and suction nozzle recycling box, and the suction nozzle recycling box is located at the suction nozzle frame one
End, the suction nozzle recycling box are opposite with the waste liquid placement section.
The suction nozzle frame is equipped with the suction nozzle putting hole for penetrating through the suction nozzle frame.
The sample placement section includes specimen holder and sample placement plate, and the sample placement plate, which is equipped with, penetrates through the sample
The test tube putting hole of placement plate, the sample placement plate are located on the specimen holder.
Sample placement plate one end be equipped with the first fool proof pin, the specimen holder be equipped with the first fool proof hole, described first
Fool proof pin is corresponding with first fool proof hole.
The other end opposite with the first fool proof pin is additionally provided with the first positioning pin, the sample in the sample placement plate
Frame is equipped with first positioning hole, and first positioning pin is corresponding with the first positioning hole.
Film-making dyeing portion includes film-making dyeing support and film-making dyed plate, and the film-making dyed plate is located at the film-making
On dyeing support, the film-making dyed plate is equipped with slide and places position.
Film-making dyed plate one end is equipped with the second fool proof pin, and the film-making dyeing support is equipped with the second fool proof hole, institute
It is corresponding with second fool proof hole to state the second fool proof pin.
Opposite both ends are respectively equipped with the second positioning pin on the film-making dyed plate, and the film-making dyeing support is equipped with the
Two location holes, second positioning pin are corresponding with the second location hole.
Leveling portion is additionally provided on the film-making dyeing support, the leveling portion is connected with the film-making dyed plate.
All-in-one machine, including rack, manipulator, mechanical arm drive mechanism and work as described in any one of the above embodiments are dyed in film-making
Platform, the manipulator, the mechanical arm drive mechanism and the workbench are located in the rack, the mechanical arm drive mechanism
It is connected with the manipulator, the manipulator is located above the workbench.
The manipulator includes transfer dyeing mechanism, wiper mechanism and guide rail mechanism, and the guide rail mechanism is led including first
Rail and the second guide rail, first guide rail and second guide rail are in same level, the transfer dyeing mechanism and institute
It states the first guide rail to be connected, the wiper mechanism is connected with second guide rail, the transfer dyeing mechanism and the wiper mechanism
The opposite two sides of first guide rail, the second guide rail are located at, first guide rail is two, and two described first are led
Rail is located at the two sides of second guide rail.
The transfer dyeing mechanism includes the first driving motor, the first sliding block mainboard, takes tube head and air pump, and described first drives
Dynamic motor is connected with the first sliding block mainboard, and the first sliding block mainboard is located on first guide rail, described to take tube head position
In on the first sliding block mainboard, described that tube head one end is taken to be equipped with appendix, the appendix other end is connected with the air pump.
The first sliding block mainboard, which is equipped with, takes tube socket, described that tube head is taken to be located at described take on tube socket.
First bearing seat is additionally provided on the first sliding block mainboard, the main shaft of first driving motor passes through described first
It is connected after bearing block and with the first bearing seat.
The appendix is equipped with negative-pressure detection device, and the negative-pressure detection device takes tube head and the air pump positioned at described
Between, the negative-pressure detection device detects the negative pressure variation of the appendix.
The wiper mechanism include the second driving motor, the second sliding block mainboard and liquid feeding portion, second driving motor with
The second sliding block mainboard is connected, and the second sliding block mainboard is located on second guide rail, and the liquid feeding portion is positioned at described the
On two sliding block mainboards.
The second sliding block mainboard is equipped with fixed plate, and the liquid feeding portion is located in the fixed plate.
The liquid feeding portion includes liquid-feeding tube and waste suction liquid pipe, and the liquid-feeding tube is located in the waste suction liquid pipe, the liquid feeding
The bottom of pipe extends along the waste suction liquid pipe to the oblique upper far from the waste suction liquid pipe, and the bottom of the liquid-feeding tube is higher than described
The bottom of waste suction liquid pipe.
The wiper mechanism further includes reagent storage device, and the top of the liquid-feeding tube and the waste suction liquid pipe is equipped with infusion
Pipe, the one end for the perfusion tube being connected with the liquid-feeding tube is connected with the reagent storage device.
The second sliding block mainboard is equipped with second bearing seat, second driving motor and the second bearing seat phase
Even.
The wiper mechanism further includes reagent detection device, and the reagent detection device and the reagent store
Device is connected.
The wiper mechanism is located at the front side of the transfer dyeing mechanism.
The mechanical arm drive mechanism includes third driving motor, the 4th driving motor, X-axis guide rail and Y-axis guide rail, described
Third driving motor is connected with the Y-axis guide rail, and the Y-axis guide rail is located in the X-axis guide rail, the 4th driving motor with
The manipulator is connected, and the manipulator is located in the Y-axis guide rail.
The rack includes main stand lid, and the housing cap is connect with the subject activity, and the housing cap will be described
Manipulator, mechanical arm drive mechanism and workbench bag are wrapped in the body interior.
It should be understood that
Aforementioned " first, second, third ... " is only used for the differentiation for title, does not represent specific quantity and suitable
Sequence；
Aforementioned " side " refers in particular to a direction of something or other, refers generally to left side, right side, front side, rear side, before the application middle finger
Side or rear side；
Aforementioned " one end " refers to one of object, any end or object in the left and right ends of the application middle finger object
The inlet end of top one end or appendix, outlet side；
The advantages of below to the utility model or principle are illustrated:
1, film-making dyes all-in-one machine before operation, and suction nozzle is first placed in suction nozzle placement section, and dye liquor is placed in dye liquor placement
Portion, tissue specimen are placed in sample placement section, slide are placed in film-making dyeing portion, while preparation bin is placed on slide, system
When piece overflow dyeing machine is run, manipulator is first moved to suction nozzle placement section and draws suction nozzle, and then mechanical hand-motion suction nozzle is moved to sample
Placement section draws a certain amount of tissue specimen by suction nozzle, and manipulator is moved to film-making dyeing portion, and tissue specimen is placed in system
In piece storehouse, then manipulator is moved to dye liquor placement section and draws a certain amount of dye liquor by suction nozzle, and manipulator is moved to film-making dye
Dye liquor is placed in preparation bin by color portion dyes tissue specimen, and then manipulator is moved to suction nozzle placement section desorption pipe,
Manipulator is moved to film-making dyeing portion and cleans to tissue specimen after tissue specimen dyeing, completes the film-making dyeing of tissue specimen
With cleaning, the workbench setting that all-in-one machine is dyed in film-making is relatively reasonable, and stroke is most short optimal in the process of running for manipulator, and
It will not will not be handed between suction nozzle placement section, film-making dyeing portion, dye liquor placement section and sample placement section in film-making dyeing course
Fork pollution, transfer sample, specimen staining and the cleaning of manipulator are arranged relatively reasonable.
2, the waste liquid placement section on workbench prevents discarded dye liquor to dye liquor placement section for placing discarded dye liquor
Dye liquor pollutes.
3, for placing suction nozzle, suction nozzle is placed in suction nozzle putting hole the suction nozzle frame of suction nozzle placement section, is convenient for manipulator pair
The absorption of suction nozzle, suction nozzle recycling box are used to place contaminated or damage suction nozzle, prevent the suction of contaminated suction nozzle or damage
Mouth causes to obscure with the suction nozzle on suction nozzle frame.
4, tissue specimen is placed in test tube, and the test tube for holding tissue specimen is placed in the test tube putting hole of sample placement plate
Interior, test tube is fixed in test tube putting hole, and test tube is effectively prevent to topple over.
5, position is placed when the first fool proof pin and the first fool proof hole can effectively prevent sample placement plate to be placed on specimen holder
Mistake, the first positioning pin and first positioning hole realize the positioning of sample placement plate and specimen holder.
6, the slide on film-making dyed plate is placed as placing slide, and the second fool proof pin in film-making dyeing portion and second prevent
Slow-witted hole effectively prevent film-making dyed plate to be placed in the upper placement location mistake of film-making dyeing support, the second positioning pin and second location hole
Realize the location and installation of film-making dyed plate and film-making dyeing support.
7, film-making is placed for leveling to film-making dyed plate placed thereon by the leveling portion on film-making dyeing support
Dyed plate tilts, to influence the dyeing of tissue specimen disposed thereon.
8, the manipulator of film-making dyeing all-in-one machine is connected with mechanical arm drive mechanism, and mechanical arm drive mechanism drives manipulator
Side left and right or back-and-forth motion on the table, are shifted, dyed and are cleaned to the tissue specimen being placed on workbench, full mistake
The operation of journey automatic integratedization improves the working efficiency of film-making dyeing all-in-one machine, has saved cost of labor.
9, transfer dyeing mechanism is connected with the first guide rail, and wiper mechanism is connected with the second guide rail, transfer dyeing mechanism and clear
Washing machine structure is located at the opposite two sides of the first guide rail, the second guide rail, may be at the first guide rail and the second guide rail same
In plane, facilitates the installation of transfer dyeing mechanism and wiper mechanism while the width for reducing manipulator, make manipulator can
To be made narrow, reduce the installation space of manipulator, keeps the structure of manipulator more succinct.
10, two the first guide rails are located at the two sides of the second guide rail, transfer dyeing mechanism and cleaning machine on manipulator
After structure installation, the weight of the two sides of manipulator can achieve the state of relative equilibrium, convenient for the movement and control of manipulator.
11, the first driving motor of transfer dyeing mechanism drives the first sliding block mainboard to move up and down on the first guide rail, the
The drive of one sliding block mainboard takes tube head to move up and down, and tube head is taken to be connected by appendix with air pump, and air pump control takes tube head to draw suction
Mouth, and pass through suction nozzle aspirates tissue sample or dye liquor, the transfer and dyeing of control group price card sheet.
12, the negative-pressure detection device on appendix is by the negative pressure transformation in detection appendix, and judges to take tube head with this
Suction nozzle, tissue specimen and dye liquor etc. are whether drawn, prevents that tube head is taken the case where leakage is drawn occur, improves the transfer of dyeing machine
Tissue specimen and the accuracy of dyeing.
13, the second driving motor of wiper mechanism drives the second sliding block mainboard to move up and down on the second guide rail, and second is sliding
Block mainboard drives liquid feeding portion to move up and down, and liquid feeding portion realizes cleaning to tissue specimen and discharge clearly during moving up and down
Wash reagent.
14, the cleaning reagent in reagent storage device is entered in liquid-feeding tube by perfusion tube, and cleaning reagent passes through liquid feeding
Pipe is expelled in preparation bin and cleans to tissue specimen, and after tissue specimen cleaning, cleaning reagent is discharged by waste suction liquid pipe, group
The discharge of the cleaning and cleaning reagent of knitting sample is relatively simple.
15, the bottom of liquid-feeding tube extends along waste suction liquid pipe to the oblique upper far from waste suction liquid pipe, and liquid-feeding tube is cleaned in addition
When reagent, cleaning reagent is expelled on the inner wall of preparation bin, and then cleaning reagent is flowed on slide by the inside of preparation bin, is prevented
Only the cleaning reagent in liquid-feeding tube, which is directly sprayed on slide, breaks up tissue specimen.
16, the bottom of liquid-feeding tube is higher than the bottom of waste suction liquid pipe, such to be arranged when cleaning reagent is discharged, and can effectively prevent
Cleaning reagent enters in liquid-feeding tube.
17, the cleaning reagent amount in reagent detection device detection reagent detection device, when cleaning reagent amount is less than one
After quantitative, operator can be reminded to add cleaning reagent.
18, mechanical arm drive mechanism lead agency hand moves left and right, in X-axis in Y-axis back-and-forth motion, thus implementation mechanism hand
On transfer dyeing mechanism and wiper mechanism three-dimensional motion.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the film-making dyeing all-in-one machine of first embodiment；
Fig. 2 is the manipulator of first embodiment and the constitutional diagram of mechanical arm drive mechanism；
Fig. 3 is the topology layout figure of the workbench of first embodiment；
Fig. 4 is the structural scheme of mechanism of the dye liquor placement section of first embodiment；
Fig. 5 is the bottom view of the sample placement plate of this first embodiment；
Fig. 6 is the sample placement plate and specimen holder combination diagram of first embodiment；
Fig. 7 is the structural scheme of mechanism in the film-making dyeing portion of first embodiment；
Fig. 8 is the structural schematic diagram one of the film-making dyed plate of first embodiment；
Fig. 9 is the structural schematic diagram two of the film-making dyed plate of first embodiment；
Figure 10 is the structural schematic diagram one of the manipulator of first embodiment；
Figure 11 is the structural schematic diagram two of the manipulator of first embodiment；
Figure 12 is the schematic diagram of the negative-pressure detection device of first embodiment；
Figure 13 is the reagent detection device of first embodiment and the schematic diagram of reagent storage device；
Figure 14 is the topology layout figure of the workbench of second embodiment；
Description of symbols:
100, rack；200, mechanical arm drive mechanism；300, workbench；110, main body；120, housing cap；310, sample is put
Set portion；320, dye liquor placement section；330, film-making dyeing portion；340, waste liquid placement section；321, dye liquor rack；322, color solution bottle is put
Set hole；350, suction nozzle placement section；351, suction nozzle frame；352, suction nozzle recycling box；3511, suction nozzle putting hole；3521, tube sheet is moved back；
3522, tube sheet support frame is moved back；3523, suction nozzle moves back pipe position；311, specimen holder；312, sample placement plate；313, test tube putting hole；
314, test tube；315, the first fool proof pin；316, the first fool proof hole；317, the first positioning pin；318, first positioning hole；331, film-making
Dyeing support；332, film-making dyed plate；333, slide places position；334, the second fool proof pin；335, the second positioning pin；336, second
Location hole；337, leveling portion；338, handle；339, mounting hole；400, manipulator；410, the first guide rail；420, the second guide rail；
411, the first sliding block；421, the second sliding block；430, the first driving motor；440, the first sliding block mainboard；450, tube head is taken；451, gas
Pump；441, first bearing seat；431, the first feed screw nut；442, tube socket is taken；500, negative-pressure detection device；460, the second driving electricity
Machine；470, the second sliding block mainboard；480, reagent storage device；471, second bearing seat；461, the second feed screw nut；472, fixed
Seat；491, liquid-feeding tube；492, waste suction liquid pipe；600, reagent detection device；401, top plate；402, pinboard；700, slide；
800, preparation bin；210, third driving motor；220, the 4th driving motor；230, X-axis guide rail；240, Y-axis guide rail.
Specific embodiment
The embodiments of the present invention are described in detail below.
First embodiment:
As shown in Figure 1 and Figure 2, the present embodiment discloses a kind of film-making dyeing all-in-one machine, including rack 100, robot drives machine
Structure 200, workbench 300 and manipulator 400, wherein manipulator 400, mechanical arm drive mechanism 200 and workbench 300 are located at rack
On 100, manipulator 400 is located at the top of workbench 300, and manipulator 400 is connected with mechanical arm drive mechanism 200, and manipulator
200 driving manipulator 400 of driving mechanism left and right or back-and-forth motion above workbench 300, the rack 100 of the present embodiment include master
Body 110 and housing cap 120, housing cap 120 are located in main body 110, and main body 110 and housing cap 120 are by manipulator 400, manipulator
Driving mechanism 200 and workbench 300 are wrapped in inside it.
It is put as shown in Figure 1, the workbench 300 of the present embodiment is equipped with sample placement section 310, suction nozzle placement section 350, dye liquor
Portion 320, film-making dyeing portion 330 and waste liquid placement section 340 are set, manipulator 400 is located on one end opposite with film-making dyeing portion 330
Side, wherein film-making dyeing portion 330 is located at one end of dye liquor placement section 320 and sample placement section 310, and dye liquor placement section 320 is located at
Between waste liquid placement section 340 and film-making dyeing portion 330, waste liquid placement section 340 is located at suction nozzle placement section 350 and dye liquor placement section
Between 320, sample placement section 310 is located at 320 side of dye liquor placement section, and the waste liquid placement section 340 of the present embodiment is waste liquid placement
Slot, as shown in figure 3, the dye liquor placement section 320 of the present embodiment includes dye liquor rack 321, dye liquor rack 321 is equipped with dye liquor
Bottle putting hole 322；The suction nozzle placement section 350 of the present embodiment includes suction nozzle frame 351 and suction nozzle recycling box 352, is set on suction nozzle frame 351
There is the suction nozzle putting hole 3511 of several perforation suction nozzles, film-making dyes all-in-one machine when in use, can be in advance in suction nozzle putting hole 3511
It is inside put into suction nozzle, suction nozzle recycling box 352 is located at the side of suction nozzle frame 351, and suction nozzle recycling box 352 is located at sample placement section 310
The other end, suction nozzle recycling box 352 are equipped with and move back tube sheet 3521 and two are moved back tube sheet support frame 3522, and two are moved back tube sheet support frame
3522 both ends are located on the opposite two sides of suction nozzle recycling box 352, are moved back 3521 bottom of tube sheet and are fixed on two and move back pipe
In plate bracing frame 3522, tube sheet 3521 is moved back equipped with suction nozzle and moves back pipe position 3523, damage or pollution suction nozzle passes through manipulator 400
It is moved to and moves back on tube sheet 3521, then the suction nozzle moved back on tube sheet 3521 is put into suction nozzle recycling box 352 again；
As shown in figure 4, the sample placement section 310 of the present embodiment includes specimen holder 311 and sample placement plate 312, this implementation
The quantity of the sample placement plate 312 of example is four, and four sample placement plates 312 are located on specimen holder 311, in the present embodiment
In order to facilitate the placement of tissue specimen, the examination of several perforation sample placement plates 312 is respectively equipped in each sample placement plate 312
Pipe putting hole 313, film-making dye all-in-one machine when in use, and the test tube 314 equipped with tissue specimen is placed in test tube putting hole 313
It is interior, meanwhile, the present embodiment situations such as sample placement plate 312 is placed in 311 upper placement location mistake of specimen holder in order to prevent
Generation, as shown in Figure 5, Figure 6, the present embodiment also one end of sample placement plate 312 bottom be provided with four the first fool proofs
Pin 315 is provided with four the first fool proof holes 316, four the first fool proof pins 315 and four the first fool proof holes on specimen holder 311
316 is corresponding, while being equipped with the first positioning pin 317 in the bottom of the other end of sample placement plate 312, and specimen holder 311 is equipped with
First positioning hole 318, the first positioning pin 317 are corresponding with first positioning hole 318；
As shown in Fig. 7 to Fig. 8, the film-making dyeing portion 330 of the present embodiment includes film-making dyeing support 331 and film-making dyed plate
332, film-making dyed plate 332 is located on film-making dyeing support 331, and film-making dyed plate 332 is equipped with several slides and places position 333,
Film-making dyed plate 332 is placed in film-making dyeing support 331 upper placement location mistake, the present embodiment in order to prevent
It is equipped with the second fool proof pin 334 in 332 one end of film-making dyed plate, is equipped with the second fool proof hole (in figure not on film-making dyeing support 331
Show), the second fool proof pin 334 is corresponding with the second fool proof hole, while opposite both ends on film-making dyed plate 332 are respectively equipped with
Second positioning pin 335, film-making dyeing support 331 are equipped with second location hole 336, the second positioning pin 335 and second location hole 336
It is corresponding, leveling portion 337 is additionally provided on the film-making dyeing support 331 of the present embodiment, the leveling portion 337 of the present embodiment is leveling spiral shell
Silk etc., leveling portion 337 is connected with film-making dyed plate 332, and in order to facilitate the pick-and-place of film-making dyed plate 332, the present embodiment is also being made
Piece dyed plate 332 is equipped with handle 338, and film-making dyed plate 332 is equipped with mounting hole 339, and 338 both ends of handle are installed on mounting hole
In 339；
In the present embodiment, film-making dyed plate 332 is four, 332 arranged in parallel of any two of them film-making dyed plate, in reality
In the application of border, according to the needs of use, film-making dyed plate 332 can be set to six or eight etc..
As shown in Figure 10, Figure 11, the manipulator 400 of the present embodiment includes transfer dyeing mechanism, wiper mechanism and guide rail machine
Structure, wherein guide rail mechanism includes the first guide rail 410 and the second guide rail 420, and 410 quantity of the first guide rail is two, and two first are led
Rail 410 is located at the two sides of the second guide rail 420, and two the first guide rails 410 and the second guide rail 420 are in the same plane,
Be respectively equipped with the first sliding block 411 on two the first guide rails 410, transfer dyeing mechanism by the first sliding block 411 respectively with two the
One guide rail 410 is connected, and the second guide rail 420 is equipped with the second sliding block 421, and wiper mechanism passes through the second sliding block 421 and the second guide rail
420 are connected, and transfer dyeing mechanism is located at the opposite two sides of the first guide rail 410, the second guide rail 420 with wiper mechanism,
And wiper mechanism is located at the front side of transfer dyeing mechanism.
The transfer dye liquor mechanism of the present embodiment include the first driving motor 430, the first sliding block mainboard 440, take tube head 450 and
Air pump 451, the first sliding block mainboard 440 are fixed on the first sliding block 411, and first driving motor 430 of the present embodiment is ball wire
Bar motor, the first sliding block mainboard 440 are equipped with first bearing seat 441, and the main shaft of the first driving motor 430 passes through first bearing seat
It is connected after 441 and with first bearing seat 441, the first feed screw nut 431 of the first driving motor 430 is located at first bearing seat 441
Lower section, the first feed screw nut 431 by first bearing seat 441 drive the first sliding block mainboard 440 on the first guide rail 410 up and down
Mobile, the first sliding block mainboard 440, which is equipped with, takes tube socket 442, and the tube socket 442 that takes of the present embodiment is four, each to take on tube socket 442
It is respectively equipped with one and takes tube head 450, the top for taking tube head 450 of the present embodiment is equipped with appendix (not shown), appendix
One end is connected with air pump 451, and the air pump 451 of the present embodiment is equipped with negative-pressure detection device 500.
The wiper mechanism of the present embodiment includes the second driving motor 460, the second sliding block mainboard 470, liquid feeding portion and reagent storage
Cryopreservation device 480, wherein the second sliding block mainboard 470 is fixed on the second sliding block 421, second driving motor 460 of the present embodiment
For ball screw motor, the second sliding block mainboard 470 is equipped with second bearing seat 471, and the main shaft of the second driving motor 460 passes through the
It is connected after two bearing bracket 471 and with second bearing seat 471, the second feed screw nut 461 of the second driving motor 460 is located at the second axis
The lower section of seat 471 is held, the second feed screw nut 461 drives the second sliding block mainboard 470 in the second guide rail by second bearing seat 471
It is moved up and down on 420, the second sliding block mainboard 470 is equipped with fixing seat 472, and liquid feeding portion is located in fixed plate, and the present embodiment is consolidated
Reservation 472 is four, fixes a liquid feeding portion in each fixing seat 472, liquid feeding portion includes liquid-feeding tube 491 and waste suction liquid pipe
492, liquid-feeding tube 491 is located in waste suction liquid pipe 492, and the bottom of liquid-feeding tube 491 is along waste suction liquid pipe 492 to far from waste suction liquid pipe 492
Oblique upper extend, and the bottom of liquid-feeding tube 491 be higher than waste suction liquid pipe 492 bottom, the liquid-feeding tube 491 and waste suction of the present embodiment
The top of liquid pipe 492 is respectively equipped with perfusion tube (not shown), and the other end for the perfusion tube being connected with liquid-feeding tube 491 and examination
Agent storage device 480 is connected, and the cleaning reagent reagent in reagent storage device 480 is added to by perfusion tube and liquid-feeding tube 491
The tissue specimen on slide 700 is cleaned on slide 700, the cleaning reagent after cleansing tissue sample is discharged by waste suction liquid pipe 492,
In order to detect to the cleaning reagent in reagent storage device 480, the present embodiment is additionally provided with reagent detection device 600,
Reagent detection device 600 is connected with reagent storage device 480.
The manipulator 400 of the present embodiment further includes top plate 401, the first driving motor 430 and the second driving motor 460 difference
Positioned at the upper surface of top plate 401, the first guide rail 410, the second guide rail 420 top be individually fixed in the lower surface of top plate 401, push up
A side of plate 401 is equipped with pinboard 402, and pinboard 402 is fixed in mechanical arm drive mechanism 200.
The present embodiment take tube head 450 and liquid feeding portion is four, dyeing and clear can be carried out to four tissue specimens simultaneously
It washes, in the application, the quantity for taking tube head 450 and liquid feeding portion can be also increased or decreased according to use demand.
The mechanical arm drive mechanism 200 of the present embodiment is led including third driving motor 210, the 4th driving motor 220, X-axis
Rail 230 and Y-axis guide rail 240, third driving motor 210 are connected with Y-axis guide rail 240, and Y-axis guide rail 240 is located in X-axis guide rail 230,
Third driving motor 210 drives Y-axis guide rail 240 to move left and right in X-axis guide rail 230, and manipulator 400 is located at Y-axis guide rail 240
On, the 4th driving motor 220 is connected with manipulator 400, and 220 driving manipulator 400 of the 4th driving motor is in Y-axis guide rail 240
It is moved forward and backward.
The advantages of the present embodiment or principle are as follows:
1, film-making dyes all-in-one machine before operation, suction nozzle is first placed in suction nozzle placement section 350, dye liquor is placed in dye liquor and puts
Set portion 320, tissue specimen is placed in sample placement section 310, slide 700 is placed in film-making dyeing portion 330, while in slide
Preparation bin 800 is placed on 700, when dyeing machine is run, manipulator 400 is first moved to suction nozzle placement section 350 and draws suction nozzle, so
Manipulator 400 drives suction nozzle to be moved to sample placement section 310 and draws a certain amount of tissue specimen, manipulator 400 by suction nozzle afterwards
It is moved to film-making dyeing portion 330, tissue specimen is placed in preparation bin 800, then manipulator 400 is moved to dye liquor placement section
320 draw a certain amount of dye liquor by suction nozzle, and manipulator 400 is moved to film-making dyeing portion 330 and dye liquor is placed in preparation bin 800
Interior to dye to tissue specimen, then manipulator 400 is moved to 350 desorption pipe of suction nozzle placement section, machine after tissue specimen dyeing
Tool hand 400 is moved to film-making dyeing portion 330 and cleans to tissue specimen, completes the film-making dyeing and cleaning of tissue specimen, system
The workbench 300 of piece dyeing all-in-one machine is arranged relatively reasonable, and stroke is most short optimal in the process of running for manipulator 400, and is making
It will not be between suction nozzle placement section 350, film-making dyeing portion 330, dye liquor placement section 320 and sample placement section 310 in piece dyeing course
Cross contamination will not occur, transfer sample, specimen staining and the cleaning of manipulator 400 are arranged relatively reasonable.
2, the waste liquid placement section 340 on workbench 300 prevents discarded dye liquor from putting to dye liquor for placing discarded dye liquor
The dye liquor for setting portion 320 pollutes.
3, the suction nozzle frame 351 of suction nozzle placement section 350 is for placing suction nozzle, and suction nozzle is placed in suction nozzle putting hole 3511, just
In absorption of the manipulator 400 to suction nozzle, suction nozzle recycling box 352 is used to place contaminated or damage suction nozzle, prevents from being contaminated
Suction nozzle or the suction nozzle of damage cause to obscure with the suction nozzle on suction nozzle frame 351.
4, tissue specimen is placed in test tube 314, and the test tube 314 for holding tissue specimen is placed in sample placement plate 312
In test tube putting hole 313, test tube 314 is fixed in test tube putting hole 313, and test tube 314 is effectively prevent to topple over.
5, the first fool proof pin 315 and the first fool proof hole 316 can effectively prevent sample placement plate 312 to be placed in specimen holder 311
Placement mistake in position when upper, the first positioning pin 317 and the realization sample placement plate 312 of first positioning hole 318 are determined with specimen holder 311
Position.
6, the slide 700 on film-making dyed plate 332 is placed as placing slide 700, and the second of film-making dyeing portion 330 is anti-
Slow-witted pin 334 and the second fool proof hole effectively prevent film-making dyed plate 332 to be placed in the upper placement location mistake of film-making dyeing support 331,
Second positioning pin 335 and second location hole 336 realize the location and installation of film-making dyed plate 332 and film-making dyeing support 331.
7, the leveling portion 337 on film-making dyeing support 331 is for adjusting film-making dyed plate 332 placed thereon
It is flat, it places film-making dyed plate 332 and tilts, to influence the dyeing of tissue specimen disposed thereon.
8, transfer dyeing mechanism is connected with the first guide rail 410, and wiper mechanism is connected with the second guide rail 420, transfer dyeing machine
Structure and the wiper mechanism two sides that be located at the first guide rail 410, the second guide rail 420 opposite, lead the first guide rail 410 with second
Rail 420 may be on same plane, facilitate transfer dyeing mechanism and cleaning machine while reducing the width of manipulator 400
The installation of structure allows manipulator 400 to be made narrow, reduces the installation space of manipulator 400, makes the structure of manipulator 400
It is more succinct.
9, two the first guide rails 410 are located at the two sides of the second guide rail 420, the transfer dyeing mechanism on manipulator 400
After wiper mechanism installation, the weight of the two sides of manipulator 400 can achieve the state of relative equilibrium, be convenient for manipulator 400
Movement and control.
10, transfer dyeing mechanism the first driving motor 430 drive the first sliding block mainboard 440 on the first guide rail 410 on
Lower movement, the drive of the first sliding block mainboard 440 take tube head 450 to move up and down, tube head 450 are taken to be connected by appendix with air pump 451,
The control of air pump 451 takes tube head 450 to draw suction nozzle, and passes through suction nozzle aspirates tissue sample or dye liquor, the transfer of control group price card sheet
And dyeing.
11, the negative-pressure detection device 500 on appendix is by the negative pressure transformation in detection appendix, and judges to take pipe with this
Whether first 450 draw suction nozzle, tissue specimen and dye liquor etc., prevents that tube head 450 is taken the case where leakage is drawn occur, and improves film-making dyeing
The transfer tissue specimen of machine and the accuracy of dyeing.
12, the manipulator 400 of film-making dyeing all-in-one machine is connected with mechanical arm drive mechanism 200, mechanical arm drive mechanism 200
Manipulator 400 left and right or back-and-forth motion above workbench 300 are driven, the tissue specimen being placed on workbench 300 is carried out
Transfer, dyeing and cleaning, the operation of overall process automatic integratedization improve the working efficiency of film-making dyeing all-in-one machine, have saved people
Work cost.
13, wiper mechanism the second driving motor 460 drive the second sliding block mainboard 470 on the second guide rail 420 on move down
Dynamic, the second sliding block mainboard 470 drives liquid feeding portion to move up and down, and liquid feeding portion realizes during moving up and down to tissue specimen
Cleaning and discharge cleaning reagent.
14, the cleaning reagent in reagent storage device 480 is entered in liquid-feeding tube 491 by perfusion tube, cleaning reagent warp
It crosses liquid-feeding tube 491 and is expelled in preparation bin 800 and tissue specimen is cleaned, after tissue specimen cleaning, cleaning reagent passes through suction
Sewer pipe 492 is discharged, and the cleaning of tissue specimen and the discharge of cleaning reagent are relatively simple.
15, the bottom of liquid-feeding tube 491 extends along waste suction liquid pipe 492 to the oblique upper far from waste suction liquid pipe 492, liquid-feeding tube
491 when adding cleaning reagent, and cleaning reagent is expelled on the inner wall of preparation bin 800, and then cleaning reagent passes through preparation bin 800
Inside flow on slide 700, prevent the cleaning reagent in liquid-feeding tube 491 to be directly sprayed on slide 700 and break up tissue specimen.
16, the bottom of liquid-feeding tube 491 is higher than the bottom of waste suction liquid pipe 492, such to be arranged when cleaning reagent is discharged, and can have
Effect prevents cleaning reagent from entering in liquid-feeding tube 491.
17, the cleaning reagent amount in 600 detection reagent detection device of reagent detection device, when cleaning reagent amount is less than
After a certain amount of, operator can be reminded to add cleaning reagent.
18,200 lead agency hand of mechanical arm drive mechanism moves left and right, in X-axis in Y-axis back-and-forth motion, to realize machine
The three-dimensional motion of structure transfer dyeing mechanism on hand and wiper mechanism.
Second embodiment:
As shown in Figure 1 and Figure 2, the present embodiment also discloses a kind of film-making dyeing all-in-one machine, including rack 100, robot drives
Mechanism 200, workbench 300 and manipulator 400, wherein rack 100, mechanical arm drive mechanism 200, manipulator 400 and first are real
Apply that example is identical, the workbench 300 of the present embodiment is equipped with sample placement section 310, suction nozzle placement section 350, dye liquor placement section
320, film-making dyeing portion 330 and waste liquid placement section 340, the sample placement section 310, suction nozzle placement section 350, dye liquor of the present embodiment are put
Set portion 320, the layout of film-making dyeing portion 330 and waste liquid placement section 340 on the table is different from the first embodiment:
As shown in figure 14, the film-making dyeing portion 330 of the present embodiment is located at dye liquor placement section 320 and waste liquid placement section 340
One end, dye liquor placement section 320 are located between sample placement section 310 and film-making dyeing portion 330, and suction nozzle placement section 350 is located at sample
The side of placement section 310, wherein suction nozzle placement section 350 includes suction nozzle frame 351 and suction nozzle recycling box 352, suction nozzle recycling box 352
Positioned at one end of suction nozzle frame 351, and suction nozzle recycling box 352 and waste liquid placement section 340 are opposite, the suction nozzle recycling box of the present embodiment
352 equipped with tube sheet 3521 is moved back, and the bottom for moving back tube sheet 352 is fixed in suction nozzle recycling box 352, moves back tube sheet 352 equipped with suction nozzle
Pipe position 3523 is moved back, the sample placement section 310 of the present embodiment includes specimen holder 311 and sample placement plate 312, in the present embodiment,
Dye liquor placement section 320 and waste liquid placement section 340 are respectively positioned on specimen holder 311.
The above are only specific embodiments of the present invention, does not limit the protection scope of the utility model with this；Not
It violates made any replacement on the basis of the utility model is conceived and improves, the category protection scope of the utility model.
Claims (29)
1. workbench, which is characterized in that described including sample placement section, suction nozzle placement section, dye liquor placement section and film-making dyeing portion
Film-making dyeing part is in one end of the dye liquor placement section and sample placement section, and the dye liquor placement section is located at the suction nozzle and puts
It sets between portion and film-making dyeing portion, the sample placement section is located at the side of dye liquor placement section.
2. workbench as described in claim 1, which is characterized in that be additionally provided with waste liquid placement section, the waste liquid on the workbench
Placement section is between the suction nozzle placement section and the dye liquor placement section.
3. workbench as described in claim 1, which is characterized in that the suction nozzle placement section includes suction nozzle frame and suction nozzle recycling box,
The suction nozzle recycling box is located at the side of the suction nozzle frame, and the suction nozzle recycling box is located at one end of the sample placement section,
The suction nozzle recycling box is opposite with film-making dyeing portion.
4. workbench, which is characterized in that described including sample placement section, suction nozzle placement section, dye liquor placement section and film-making dyeing portion
Film-making dyeing part is located at the sample in one end of the dye liquor placement section and the suction nozzle placement section, the dye liquor placement section
Between placement section and film-making dyeing portion, the suction nozzle placement section is located at the side of the sample placement section.
5. workbench as claimed in claim 4, which is characterized in that be additionally provided with waste liquid placement section, the waste liquid on the workbench
Placement section is between the suction nozzle placement section and film-making dyeing portion.
6. workbench as claimed in claim 5, which is characterized in that the suction nozzle placement section includes suction nozzle frame and suction nozzle recycling box,
The suction nozzle recycling box is located at suction nozzle frame one end, and the suction nozzle recycling box is opposite with the waste liquid placement section.
7. the workbench as described in claim 3 or 6 any one, which is characterized in that the suction nozzle frame, which is equipped with, penetrates through the suction nozzle
The suction nozzle putting hole of frame.
8. the workbench as described in any one of claims 1 to 6, which is characterized in that the sample placement section include specimen holder and
Sample placement plate, the sample placement plate are equipped with the test tube putting hole for penetrating through the sample placement plate, the sample placement plate
On the specimen holder.
9. workbench as claimed in claim 8, which is characterized in that sample placement plate one end is equipped with the first fool proof pin, described
Specimen holder is equipped with the first fool proof hole, and the first fool proof pin is corresponding with first fool proof hole.
10. workbench as claimed in claim 9, which is characterized in that opposite with the first fool proof pin in the sample placement plate
The other end be additionally provided with the first positioning pin, the specimen holder is equipped with first positioning hole, first positioning pin and described first
Location hole is corresponding.
11. the workbench as described in any one of claims 1 to 6, which is characterized in that film-making dyeing portion includes film-making dyeing
Bracket and film-making dyed plate, the film-making dyed plate are located on the film-making dyeing support, and the film-making dyed plate is equipped with glass
Piece places position.
12. workbench as claimed in claim 11, which is characterized in that film-making dyed plate one end is equipped with the second fool proof pin, institute
Film-making dyeing support is stated equipped with the second fool proof hole, the second fool proof pin is corresponding with second fool proof hole.
13. workbench as claimed in claim 12, which is characterized in that opposite both ends are respectively equipped on the film-making dyed plate
Two positioning pins, the film-making dyeing support are equipped with second location hole, and second positioning pin is opposite with the second location hole
It answers.
14. workbench as claimed in claim 11, which is characterized in that leveling portion is additionally provided on the film-making dyeing support, it is described
Leveling portion is connected with the film-making dyed plate.
15. all-in-one machine is dyed in film-making, which is characterized in that including rack, manipulator, mechanical arm drive mechanism and such as claim 1
To workbench described in any one of 14, the manipulator, the mechanical arm drive mechanism and the workbench are located at the machine
On frame, the mechanical arm drive mechanism is connected with the manipulator, and the manipulator is located above the workbench.
16. all-in-one machine is dyed in film-making as claimed in claim 15, which is characterized in that the manipulator include transfer dyeing mechanism,
Wiper mechanism and guide rail mechanism, the guide rail mechanism include the first guide rail and the second guide rail, first guide rail and described second
Guide rail is in same level, and the transfer dyeing mechanism is connected with first guide rail, the wiper mechanism and described the
Two guide rails are connected, the transfer dyeing mechanism and the wiper mechanism be located at first guide rail, the second guide rail it is opposite
Two sides, first guide rail be two, two first guide rails are located at the two sides of second guide rail.
17. all-in-one machine is dyed in film-making as claimed in claim 16, which is characterized in that the transfer dyeing mechanism includes the first driving
Motor, the first sliding block mainboard take tube head and air pump, and first driving motor is connected with the first sliding block mainboard, and described
One sliding block mainboard is located on first guide rail, described that tube head is taken to be located on the first sliding block mainboard, described to take tube head one end
Equipped with appendix, the appendix other end is connected with the air pump.
18. all-in-one machine is dyed in film-making as claimed in claim 17, which is characterized in that the first sliding block mainboard is equipped with and takes pipe
Seat, it is described that tube head is taken to be located at described take on tube socket.
19. all-in-one machine is dyed in film-making as claimed in claim 18, which is characterized in that be additionally provided with first on the first sliding block mainboard
The main shaft of bearing block, first driving motor is connected after the first bearing seat and with the first bearing seat.
20. all-in-one machine is dyed in film-making as claimed in claim 17, which is characterized in that the appendix is filled equipped with detection of negative pressure
It sets, the negative-pressure detection device takes between tube head and the air pump positioned at described, and the negative-pressure detection device detects the gas transmission
The negative pressure variation of pipe.
21. all-in-one machine is dyed in film-making as claimed in claim 16, which is characterized in that the wiper mechanism includes the second driving electricity
Machine, the second sliding block mainboard and liquid feeding portion, second driving motor are connected with the second sliding block mainboard, the second sliding block master
Plate is located on second guide rail, and the liquid feeding portion is located on the second sliding block mainboard.
22. all-in-one machine is dyed in film-making as claimed in claim 21, which is characterized in that the second sliding block mainboard, which is equipped with, to be fixed
Plate, the liquid feeding portion are located in the fixed plate.
23. all-in-one machine is dyed in film-making as claimed in claim 22, which is characterized in that the liquid feeding portion includes liquid-feeding tube and waste suction liquid
Pipe, the liquid-feeding tube are located in the waste suction liquid pipe, and the bottom of the liquid-feeding tube is along the waste suction liquid pipe to far from the waste suction
The oblique upper of liquid pipe extends, and the bottom of the liquid-feeding tube is higher than the bottom of the waste suction liquid pipe.
24. all-in-one machine is dyed in film-making as claimed in claim 23, which is characterized in that the wiper mechanism further includes reagent storage dress
Set, the top of the liquid-feeding tube and the waste suction liquid pipe is equipped with perfusion tube, the one end for the perfusion tube being connected with the liquid-feeding tube and
The reagent storage device is connected.
25. all-in-one machine is dyed in film-making as claimed in claim 22, which is characterized in that the second sliding block mainboard is equipped with the second axis
Seat is held, second driving motor is connected with the second bearing seat.
26. all-in-one machine is dyed in film-making as claimed in claim 24, which is characterized in that the wiper mechanism further includes reagent inspection
Device is surveyed, the reagent detection device is connected with the reagent storage device.
27. all-in-one machine is dyed in film-making as described in any one of claim 16 to 26, which is characterized in that the wiper mechanism is located at
The front side of the transfer dyeing mechanism.
28. all-in-one machine is dyed in film-making as claimed in claim 15, which is characterized in that the mechanical arm drive mechanism includes that third is driven
Dynamic motor, the 4th driving motor, X-axis guide rail and Y-axis guide rail, the third driving motor are connected with the Y-axis guide rail, the Y
Axis rail is located in the X-axis guide rail, and the 4th driving motor is connected with the manipulator, and the manipulator is located at the Y
On axis rail.
29. all-in-one machine is dyed in film-making as claimed in claim 15, which is characterized in that the rack includes main stand lid, described
Housing cap is connect with the subject activity, and the manipulator, mechanical arm drive mechanism and workbench bag are wrapped in by the housing cap
The body interior.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821792057.XU CN209231069U (en) | 2018-11-01 | 2018-11-01 | All-in-one machine is dyed in workbench and film-making with the workbench |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821792057.XU CN209231069U (en) | 2018-11-01 | 2018-11-01 | All-in-one machine is dyed in workbench and film-making with the workbench |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209231069U true CN209231069U (en) | 2019-08-09 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821792057.XU Active CN209231069U (en) | 2018-11-01 | 2018-11-01 | All-in-one machine is dyed in workbench and film-making with the workbench |
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| Country | Link |
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| CN (1) | CN209231069U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110849692A (en) * | 2019-12-20 | 2020-02-28 | 广州江元医疗科技有限公司 | Full-automatic slice-making and dyeing equipment and full-automatic slice-making and dyeing method |
-
2018
- 2018-11-01 CN CN201821792057.XU patent/CN209231069U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110849692A (en) * | 2019-12-20 | 2020-02-28 | 广州江元医疗科技有限公司 | Full-automatic slice-making and dyeing equipment and full-automatic slice-making and dyeing method |
| CN110849692B (en) * | 2019-12-20 | 2024-03-15 | 广州江元医疗科技有限公司 | Full-automatic film-making dyeing equipment and full-automatic film-making dyeing method |
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Address after: 510663 No. 2 Kexin street, Huangpu District, Guangzhou, Guangdong Patentee after: GUANGZHOU LBP MEDICINE SCIENCE AND TECHNOLOGY Co.,Ltd. Address before: 510663 building 7, No. 11, Nanxiang 3rd road, Guangzhou hi tech Industrial Development Zone, Guangdong Province Patentee before: GUANGZHOU LBP MEDICINE SCIENCE AND TECHNOLOGY Co.,Ltd. |