CN209231070U - All-in-one machine is dyed in manipulator and film-making with the manipulator - Google Patents

All-in-one machine is dyed in manipulator and film-making with the manipulator Download PDF

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Publication number
CN209231070U
CN209231070U CN201821792601.0U CN201821792601U CN209231070U CN 209231070 U CN209231070 U CN 209231070U CN 201821792601 U CN201821792601 U CN 201821792601U CN 209231070 U CN209231070 U CN 209231070U
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China
Prior art keywords
film
making
manipulator
guide rail
dyed
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Active
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CN201821792601.0U
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Chinese (zh)
Inventor
陈吾科
彭武杰
吴俊宏
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Guangzhou Lbp Medicine Science & Technology Co Ltd
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Guangzhou Lbp Medicine Science & Technology Co Ltd
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Priority to CN201821792601.0U priority Critical patent/CN209231070U/en
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Abstract

The utility model discloses a kind of manipulator and all-in-one machine is dyed in the film-making with the manipulator, it includes rack that all-in-one machine is dyed in film-making, mechanical arm drive mechanism, workbench and manipulator, manipulator, mechanical arm drive mechanism and workbench are located in rack, mechanical arm drive mechanism is connected with manipulator, manipulator is located above workbench, wherein, manipulator includes transfer dyeing mechanism, wiper mechanism and guide rail mechanism, guide rail mechanism includes the first guide rail and the second guide rail, first guide rail and the second guide rail are in same level, transfer dyeing mechanism is connected with the first guide rail, wiper mechanism is connected with the second guide rail, transfer dyeing mechanism and wiper mechanism are located at the first guide rail, the opposite two sides of second guide rail, first guide rail is two, two the first guide rails are located at the two sides of the second guide rail, the machine of film-making dyeing all-in-one machine Tool hand is relatively narrow, occupies little space.

Description

All-in-one machine is dyed in manipulator and film-making with the manipulator
Technical field
The utility model relates to medical field of biotechnology, more specifically, being a kind of manipulator and having a manipulator Film-making dye all-in-one machine.
Background technique
When carrying out disorder in screening and diagnosis using tissue, for the ease of the observation and research to tissue, in research tissue Before, it usually needs film-making dyeing is carried out to tissue, all-in-one machine is dyed in existing film-making, thereon for transfer dyeing sample and to group It knits that the manipulator that sample is cleaned is wider, manipulator is caused to occupy more installation space, dye one so as to cause film-making The volume of machine is larger.
Summary of the invention
The purpose of this utility model is to provide a kind of manipulator and all-in-one machine, the machine are dyed in the film-making with the manipulator Tool hand is relatively narrow, and the space occupied is small.
Its technical solution is as follows:
Manipulator, including transfer dyeing mechanism, wiper mechanism and guide rail mechanism, the guide rail mechanism include the first guide rail and Second guide rail, first guide rail and second guide rail be in same level, the transfer dyeing mechanism and described the One guide rail is connected, and the wiper mechanism is connected with second guide rail, and the transfer dyeing mechanism and the wiper mechanism are distinguished Positioned at the opposite two sides of first guide rail, the second guide rail, first guide rail is two, two first guide rails point Not Wei Yu second guide rail two sides.
The transfer dyeing mechanism includes the first driving motor, the first sliding block mainboard, takes tube head and air pump, and described first drives Dynamic motor is connected with the first sliding block mainboard, and the first sliding block mainboard is located on first guide rail, described to take tube head position In on the first sliding block mainboard, described that tube head one end is taken to be equipped with appendix, the appendix other end is connected with the air pump.
The first sliding block mainboard, which is equipped with, takes tube socket, described that tube head is taken to be located at described take on tube socket.
First bearing seat is additionally provided on the first sliding block mainboard, the main shaft of first driving motor passes through described first It is connected after bearing block and with the first bearing seat.
The appendix is equipped with negative-pressure detection device, and the negative-pressure detection device takes tube head and the air pump positioned at described Between, the negative-pressure detection device detects the negative pressure variation of the appendix.
The wiper mechanism include the second driving motor, the second sliding block mainboard and liquid feeding portion, second driving motor with The second sliding block mainboard is connected, and the second sliding block mainboard is located on second guide rail, and the liquid feeding portion is positioned at described the On two sliding block mainboards.
The second sliding block mainboard is equipped with fixed plate, and the liquid feeding portion is located in the fixed plate.
The liquid feeding portion includes liquid-feeding tube and waste suction liquid pipe, and the liquid-feeding tube is located in the waste suction liquid pipe, the liquid feeding The bottom of pipe extends along the waste suction liquid pipe to the oblique upper far from the waste suction liquid pipe, and the bottom of the liquid-feeding tube is higher than described The bottom of waste suction liquid pipe.
The wiper mechanism further includes reagent storage device, and the top of the liquid-feeding tube and the waste suction liquid pipe is equipped with infusion Pipe, the one end for the perfusion tube being connected with the liquid-feeding tube is connected with the reagent storage device.
The second sliding block mainboard is equipped with second bearing seat, second driving motor and the second bearing seat phase Even.
The wiper mechanism further includes reagent detection device, and the reagent detection device and the reagent store Device is connected.
The wiper mechanism is located at the front side of the transfer dyeing mechanism.
All-in-one machine, including rack, mechanical arm drive mechanism, workbench and such as aforementioned described in any item machinery are dyed in film-making Hand, the manipulator, the mechanical arm drive mechanism and the workbench are located in the rack, the mechanical arm drive mechanism It is connected with the manipulator, the manipulator is located above the workbench.
The workbench is equipped with sample placement section, suction nozzle placement section, dye liquor placement section and film-making dyeing portion, the film-making Dyeing part is in one end of the dye liquor placement section and sample placement section, and the dye liquor placement section is located at the suction nozzle placement section And between film-making dyeing portion, the sample placement section is located at the side of dye liquor placement section.
Waste liquid placement section is additionally provided on the workbench, the waste liquid placement section is located at the suction nozzle placement section and the dye Between liquid placement section.
The suction nozzle placement section includes suction nozzle frame and suction nozzle recycling box, and the suction nozzle recycling box is located at the one of the suction nozzle frame Side, and the suction nozzle recycling box is located at the other end opposite with film-making dyeing portion of the sample placement section.
The suction nozzle frame is equipped with the suction nozzle putting hole for penetrating through the suction nozzle frame.
The sample placement section includes specimen holder and sample placement plate, and the sample placement plate, which is equipped with, penetrates through the sample The test tube putting hole of placement plate, the sample placement plate are located on the specimen holder.
Sample placement plate one end be equipped with the first fool proof pin, the specimen holder be equipped with the first fool proof hole, described first Fool proof pin is corresponding with first fool proof hole.
The other end is additionally provided with the first positioning pin in the sample placement plate, and the specimen holder is equipped with first positioning hole, institute It is corresponding with the first positioning hole to state the first positioning pin.
Film-making dyeing portion includes film-making dyeing support and film-making dyed plate, and the film-making dyed plate is located at the film-making On dyeing support, the film-making dyed plate is equipped with slide and places position.
Film-making dyed plate one end is equipped with the second fool proof pin, and the film-making dyeing support is equipped with the second fool proof hole, institute It is corresponding with second fool proof hole to state the second fool proof pin.
Opposite both ends further respectively have the second positioning pin on the film-making dyed plate, and the film-making dyeing support is equipped with Second location hole, second positioning pin are corresponding with the second location hole.
The film-making dyeing support is equipped with leveling portion, and the leveling portion is connected with the film-making dyed plate.
The mechanical arm drive mechanism includes third driving motor, the 4th driving motor, X-axis guide rail and Y-axis guide rail, described Third driving motor is connected with the Y-axis guide rail, and the Y-axis guide rail is located in the X-axis guide rail, and the manipulator is located at described In Y-axis guide rail, the 4th driving motor is connected with the manipulator.
The rack includes main stand lid, and the housing cap is connect with the subject activity, and the housing cap will be described Manipulator, mechanical arm drive mechanism and workbench bag are wrapped in the body interior.
It should be understood that
Aforementioned " first, second, third ... " is only used for the differentiation for title, does not represent specific quantity and suitable Sequence;
Aforementioned " side " refers in particular to a direction of something or other, refers generally to left side, right side, front side, rear side, before the application middle finger Side or rear side;
Aforementioned " one end " refers to one of object, any end or object in the left and right ends of the application middle finger object The inlet end of top one end or appendix, outlet side;
The advantages of below to the utility model or principle are illustrated:
1, transfer dyeing mechanism is connected with the first guide rail, and wiper mechanism is connected with the second guide rail, transfer dyeing mechanism and clear Washing machine structure is located at the opposite two sides of the first guide rail, the second guide rail, may be at the first guide rail and the second guide rail same In plane, facilitates the installation of transfer dyeing mechanism and wiper mechanism while the width for reducing manipulator, make manipulator can To be made narrow, reduce the installation space of manipulator, keeps the structure of manipulator more succinct;
The manipulator of film-making dyeing all-in-one machine is connected with mechanical arm drive mechanism, and mechanical arm drive mechanism drives manipulator to exist Left and right or back-and-forth motion, are shifted, dyed and are cleaned to the tissue specimen being placed on workbench above workbench, overall process Automatic integratedization operation improves the working efficiency of film-making dyeing all-in-one machine, has saved cost of labor.
2, transfer dyeing mechanism is connected with the first guide rail, and wiper mechanism is connected with the second guide rail, transfer dyeing mechanism and clear Washing machine structure is located at the opposite two sides of the first guide rail, the second guide rail, may be at the first guide rail and the second guide rail same In plane, facilitates the installation of transfer dyeing mechanism and wiper mechanism while the width for reducing manipulator, make manipulator can To be made narrow, reduce the installation space of manipulator, keeps the structure of manipulator more succinct.
3, two the first guide rails are located at the two sides of the second guide rail, transfer dyeing mechanism and wiper mechanism on manipulator After installation, the weight of the two sides of manipulator can achieve the state of relative equilibrium, convenient for the movement and control of manipulator.
4, the first driving motor of transfer dyeing mechanism drives the first sliding block mainboard to move up and down on the first guide rail, and first The drive of sliding block mainboard takes tube head to move up and down, and tube head is taken to be connected by appendix with air pump, and air pump control takes tube head to draw suction nozzle, And pass through suction nozzle aspirates tissue sample or dye liquor, the transfer and dyeing of control group price card sheet.
5, the negative-pressure detection device on appendix is by the negative pressure transformation in detection appendix, and judges to take the tube head be with this No absorption suction nozzle, tissue specimen and dye liquor etc. prevent that tube head is taken the case where leakage is drawn occur, improve the transfer group of dyeing machine Knit the accuracy of sample and dyeing.
6, the manipulator of film-making dyeing all-in-one machine is connected with mechanical arm drive mechanism, and mechanical arm drive mechanism drives manipulator Side left and right or back-and-forth motion on the table, are shifted, dyed and are cleaned to the tissue specimen being placed on workbench, full mistake The operation of journey automatic integratedization improves the working efficiency of film-making dyeing all-in-one machine, has saved cost of labor.
7, the second driving motor of wiper mechanism drives the second sliding block mainboard to move up and down on the second guide rail, the second sliding block Mainboard drives liquid feeding portion to move up and down, and liquid feeding portion realizes cleaning and discharge cleaning to tissue specimen during moving up and down Reagent.
8, the cleaning reagent in reagent storage device is entered in liquid-feeding tube by perfusion tube, and cleaning reagent passes through liquid-feeding tube It is expelled in preparation bin and tissue specimen is cleaned, after tissue specimen cleaning, cleaning reagent is discharged by waste suction liquid pipe, tissue The cleaning of sample and the discharge of cleaning reagent are relatively simple.
9, the bottom of liquid-feeding tube extends along waste suction liquid pipe to the oblique upper far from waste suction liquid pipe, and liquid-feeding tube is in addition cleaning examination When agent, cleaning reagent is expelled on the inner wall of preparation bin, and then cleaning reagent is flowed on slide by the inside of preparation bin, is prevented Cleaning reagent in liquid-feeding tube, which is directly sprayed on slide, breaks up tissue specimen.
10, the bottom of liquid-feeding tube is higher than the bottom of waste suction liquid pipe, such to be arranged when cleaning reagent is discharged, and can effectively prevent Cleaning reagent enters in liquid-feeding tube.
11, the cleaning reagent amount in reagent detection device detection reagent detection device, when cleaning reagent amount is less than one After quantitative, operator can be reminded to add cleaning reagent.
12, film-making dyes all-in-one machine before operation, and suction nozzle is first placed in suction nozzle placement section, and dye liquor is placed in dye liquor placement Portion, tissue specimen are placed in sample placement section, slide are placed in film-making dyeing portion, while preparation bin is placed on slide, system When piece overflow dyeing machine is run, manipulator is first moved to suction nozzle placement section and draws suction nozzle, and then mechanical hand-motion suction nozzle is moved to sample Placement section draws a certain amount of tissue specimen by suction nozzle, and manipulator is moved to film-making dyeing portion, and tissue specimen is placed in system In piece storehouse, then manipulator is moved to dye liquor placement section and draws a certain amount of dye liquor by suction nozzle, and manipulator is moved to film-making dye Dye liquor is placed in preparation bin by color portion dyes tissue specimen, and then manipulator is moved to suction nozzle placement section desorption pipe, Manipulator is moved to film-making dyeing portion and cleans to tissue specimen after tissue specimen dyeing, completes the film-making dyeing of tissue specimen With cleaning, the workbench setting that all-in-one machine is dyed in film-making is relatively reasonable, and stroke is most short optimal in the process of running for manipulator, and It will not will not be handed between suction nozzle placement section, film-making dyeing portion, dye liquor placement section and sample placement section in film-making dyeing course Fork pollution, transfer sample, specimen staining and the cleaning of manipulator are arranged relatively reasonable.
13, the waste liquid placement section on workbench prevents discarded dye liquor to dye liquor placement section for placing discarded dye liquor Dye liquor pollute.
14, for placing suction nozzle, suction nozzle is placed in suction nozzle putting hole the suction nozzle frame of suction nozzle placement section, is convenient for manipulator pair The absorption of suction nozzle, suction nozzle recycling box are used to place contaminated or damage suction nozzle, prevent the suction of contaminated suction nozzle or damage Mouth causes to obscure with the suction nozzle on suction nozzle frame.
15, tissue specimen is placed in test tube, and the test tube for holding tissue specimen is placed in the test tube placement of sample placement plate In hole, test tube is fixed in test tube putting hole, and test tube is effectively prevent to topple over.
16, position is placed when the first fool proof pin and the first fool proof hole can effectively prevent sample placement plate to be placed on specimen holder Mistake, the first positioning pin and first positioning hole realize the positioning of sample placement plate and specimen holder.
17, the slide on film-making dyed plate is placed as placing slide, the second fool proof pin 334 in film-making dyeing portion and Second fool proof hole effectively prevent film-making dyed plate to be placed in the upper placement location mistake of film-making dyeing support, the second positioning pin and second The location and installation of location hole realization film-making dyed plate and film-making dyeing support.
18, system is placed for leveling to film-making dyed plate placed thereon by the leveling portion on film-making dyeing support Piece dyed plate tilts, to influence the dyeing of tissue specimen disposed thereon.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the film-making dyeing all-in-one machine of the present embodiment;
Fig. 2 is the manipulator of the present embodiment and the constitutional diagram of mechanical arm drive mechanism;
Fig. 3 is the topology layout figure of the workbench of the present embodiment;
Fig. 4 is the structural scheme of mechanism of the dye liquor placement section of the present embodiment;
Fig. 5 is the bottom view of the sample placement plate of the present embodiment;
Fig. 6 is the sample placement plate and specimen holder combination diagram of the present embodiment;
Fig. 7 is the structural scheme of mechanism in the film-making dyeing portion of the present embodiment;
Fig. 8 is the structural schematic diagram one of the film-making dyed plate of the present embodiment;
Fig. 9 is the structural schematic diagram two of the film-making dyed plate of the present embodiment;
Figure 10 is the structural schematic diagram one of the manipulator of the present embodiment;
Figure 11 is the structural schematic diagram two of the manipulator of the present embodiment;
Figure 12 is the schematic diagram of the negative-pressure detection device of the present embodiment;
Figure 13 is the reagent detection device of the present embodiment and the schematic diagram of reagent storage device;
Description of symbols:
100, rack;200, mechanical arm drive mechanism;300, workbench;110, main body;120, housing cap;310, sample is put Set portion;320, dye liquor placement section;330, film-making dyeing portion;340, waste liquid placement section;321, dye liquor rack;322, color solution bottle is put Set hole;350, suction nozzle placement section;351, suction nozzle frame;352, suction nozzle recycling box;3511, suction nozzle putting hole;3521, tube sheet is moved back; 3522, tube sheet support frame is moved back;3523, suction nozzle moves back pipe position;311, specimen holder;312, sample placement plate;313, test tube putting hole; 314, test tube;315, the first fool proof pin;316, the first fool proof hole;317, the first positioning pin;318, first positioning hole;331, film-making Dyeing support;332, film-making dyed plate;333, slide places position;334, the second fool proof pin;335, the second positioning pin;336, second Location hole;337, leveling portion;338, handle;339, mounting hole;400, manipulator;410, the first guide rail;420, the second guide rail; 411, the first sliding block;421, the second sliding block;430, the first driving motor;440, the first sliding block mainboard;450, tube head is taken; 451, Air pump;441, first bearing seat;431, the first feed screw nut;442, tube socket is taken;500, negative-pressure detection device;460, the second driving Motor;470, the second sliding block mainboard;480, reagent storage device;471, second bearing seat;461, the second feed screw nut;472, Fixing seat;491, liquid-feeding tube;492, waste suction liquid pipe;600, reagent detection device;401, top plate;402, pinboard;700, Slide;800, preparation bin;210, third driving motor;220, the 4th driving motor;230, X-axis guide rail;240, Y-axis guide rail.
Specific embodiment
The embodiments of the present invention are described in detail below.
As shown in Figure 1 and Figure 2, the present embodiment discloses a kind of film-making dyeing all-in-one machine, including rack 100, robot drives machine Structure 200, workbench 300 and manipulator 400, wherein manipulator 400, mechanical arm drive mechanism 200 and workbench 300 are located at rack On 100, manipulator 400 is located at the top of workbench 300, and manipulator 400 is connected with mechanical arm drive mechanism 200, and manipulator 200 driving manipulator 400 of driving mechanism left and right or back-and-forth motion, rack 100 of the present embodiment above workbench 300 include Main body 110 and housing cap 120, housing cap 120 are located in main body 110, and main body 110 and housing cap 120 are by manipulator 400, mechanical Hand-drive mechanism 200 and workbench 300 are wrapped in inside it.
As shown in Figure 1, the workbench 300 of the present embodiment is equipped with sample placement section 310, suction nozzle placement section 350, dye liquor Placement section 320, film-making dyeing portion 330 and waste liquid placement section 340, manipulator 400 are located at one end opposite with film-making dyeing portion 330 Top, wherein film-making dyeing portion 330 is located at one end of dye liquor placement section 320 and sample placement section 310, dye liquor placement section 320 between waste liquid placement section 340 and film-making dyeing portion 330, and waste liquid placement section 340 is located at suction nozzle placement section 350 and dye liquor Between placement section 320, sample placement section 310 is located at 320 side of dye liquor placement section, and the waste liquid placement section 340 of the present embodiment is useless Liquid placing groove is set on dye liquor rack 321 as shown in figure 3, the dye liquor placement section 320 of the present embodiment includes dye liquor rack 321 There is color solution bottle putting hole 322;The suction nozzle placement section 350 of the present embodiment includes suction nozzle frame 351 and suction nozzle recycling box 352, suction nozzle frame 351 are equipped with the suction nozzle putting hole 3511 of several perforation suction nozzles, and film-making dyes all-in-one machine when in use, can place in advance in suction nozzle Suction nozzle is put into hole 3511, suction nozzle recycling box 352 is located at the side of suction nozzle frame 351, and suction nozzle recycling box 352 is located at sample placement The other end in portion 310, suction nozzle recycling box 352 are equipped with and move back tube sheet 3521 and two are moved back tube sheet support frame 3522, and two are moved back tube sheet The both ends of support frame 3522 are located on the opposite two sides of suction nozzle recycling box 352, are moved back 3521 bottom of tube sheet and are fixed on two It is a to move back on tube sheet support frame 3522, tube sheet 3521 is moved back equipped with suction nozzle and moves back pipe position 3523, and damage or pollution suction nozzle passes through machine Tool hand 400, which is moved to, to move back on tube sheet 3521, and then the suction nozzle moved back on tube sheet 3521 is put into suction nozzle recycling box 352 again;
As shown in figure 4, the sample placement section 310 of the present embodiment includes specimen holder 311 and sample placement plate 312, this implementation The quantity of the sample placement plate 312 of example is four, and four sample placement plates 312 are located on specimen holder 311, in the present embodiment In order to facilitate the placement of tissue specimen, several perforation sample placement plates 312 are respectively equipped in each sample placement plate 312 Test tube putting hole 313, film-making dye all-in-one machine when in use, and the test tube 314 equipped with tissue specimen is placed in test tube putting hole In 313, meanwhile, sample placement plate 312 is placed in the feelings such as the upper placement location mistake of specimen holder 311 to the present embodiment in order to prevent The generation of condition, as shown in Figure 5, Figure 6, the present embodiment, which is also provided with four first in the bottom of one end of sample placement plate 312, to be prevented Slow-witted pin 315, is provided with four the first fool proof holes 316, four the first fool proof pins 315 and four the first fool proofs on specimen holder 311 Hole 316 is corresponding, while being equipped with the first positioning pin 317 in the bottom of the other end of sample placement plate 312, sets on specimen holder 311 There is first positioning hole 318, the first positioning pin 317 is corresponding with first positioning hole 318;
As shown in Fig. 7 to Fig. 8, the film-making dyeing portion 330 of the present embodiment includes film-making dyeing support 331 and film-making dyed plate 332, film-making dyed plate 332 is located on film-making dyeing support 331, and film-making dyed plate 332 is equipped with several slides and places position 333, Film-making dyed plate 332 is placed in film-making dyeing support 331 upper placement location mistake, this implementation in order to prevent Example is equipped with the second fool proof pin 334 in 332 one end of film-making dyed plate, and the second fool proof hole is equipped on film-making dyeing support 331 (in figure It is not shown), the second fool proof pin 334 is corresponding with the second fool proof hole, while opposite both ends difference on film-making dyed plate 332 Equipped with the second positioning pin 335, film-making dyeing support 331 is equipped with second location hole 336, the second positioning pin 335 and the second positioning Hole 336 is corresponding, and leveling portion 337 is additionally provided on the film-making dyeing support 331 of the present embodiment, and the leveling portion 337 of the present embodiment is Leveling serew etc., leveling portion 337 are connected with film-making dyed plate 332, in order to facilitate the pick-and-place of film-making dyed plate 332, the present embodiment Handle 338 is equipped with also on film-making dyed plate 332, film-making dyed plate 332 is equipped with mounting hole 339, and 338 both ends of handle are installed on In mounting hole 339.
As shown in Figure 10, Figure 11, the manipulator 400 of the present embodiment includes transfer dyeing mechanism, wiper mechanism and guide rail machine Structure, wherein guide rail mechanism includes the first guide rail 410 and the second guide rail 420, and 410 quantity of the first guide rail is two, two first Guide rail 410 is located at the two sides of the second guide rail 420, and two the first guide rails 410 and the second guide rail 420 are in same plane On, be respectively equipped with the first sliding block 411 on two the first guide rails 410, transfer dyeing mechanism by the first sliding block 411 respectively with two First guide rail 410 is connected, and the second guide rail 420 is equipped with the second sliding block 421, and wiper mechanism is led by the second sliding block 421 with second Rail 420 is connected, and transfer dyeing mechanism is located at the opposite two sides of the first guide rail 410, the second guide rail 420 with wiper mechanism Side, and wiper mechanism is located at the front side of transfer dyeing mechanism.
The transfer dye liquor mechanism of the present embodiment include the first driving motor 430, the first sliding block mainboard 440, take tube head 450 and Air pump 451, the first sliding block mainboard 440 are fixed on the first sliding block 411, and first driving motor 430 of the present embodiment is ball wire Bar motor, the first sliding block mainboard 440 are equipped with first bearing seat 441, and the main shaft of the first driving motor 430 passes through first bearing seat It is connected after 441 and with first bearing seat 441, the first feed screw nut 431 of the first driving motor 430 is located at first bearing seat 441 Lower section, the first feed screw nut 431 by first bearing seat 441 drive the first sliding block mainboard 440 on the first guide rail 410 up and down Mobile, the first sliding block mainboard 440, which is equipped with, takes tube socket 442, and the tube socket 442 that takes of the present embodiment is four, each to take on tube socket 442 It is respectively equipped with one and takes tube head 450, the top for taking tube head 450 of the present embodiment is equipped with appendix (not shown), appendix One end is connected with air pump 451, and the air pump 451 of the present embodiment is equipped with negative-pressure detection device 500.
The wiper mechanism of the present embodiment includes the second driving motor 460, the second sliding block mainboard 470, liquid feeding portion and reagent storage Cryopreservation device 480, wherein the second sliding block mainboard 470 is fixed on the second sliding block 421, second driving motor 460 of the present embodiment For ball screw motor, the second sliding block mainboard 470 is equipped with second bearing seat 471, and the main shaft of the second driving motor 460 passes through the It is connected after two bearing bracket 471 and with second bearing seat 471, the second feed screw nut 461 of the second driving motor 460 is located at second The lower section of bearing block 471, the second feed screw nut 461 drive the second sliding block mainboard 470 in the second guide rail by second bearing seat 471 It is moved up and down on 420, the second sliding block mainboard 470 is equipped with fixing seat 472, and liquid feeding portion is located in fixed plate, and the present embodiment is consolidated Reservation 472 is four, fixes a liquid feeding portion in each fixing seat 472, liquid feeding portion includes liquid-feeding tube 491 and waste suction liquid pipe 492, liquid-feeding tube 491 is located in waste suction liquid pipe 492, and the bottom of liquid-feeding tube 491 is along waste suction liquid pipe 492 to far from waste suction liquid pipe 492 Oblique upper extend, and the bottom of liquid-feeding tube 491 be higher than waste suction liquid pipe 492 bottom, the liquid-feeding tube 491 and waste suction of the present embodiment The top of liquid pipe 492 is respectively equipped with perfusion tube (not shown), and the other end for the perfusion tube being connected with liquid-feeding tube 491 and examination Agent storage device 480 is connected, and the cleaning reagent reagent in reagent storage device 480 is added to by perfusion tube and liquid-feeding tube 491 The tissue specimen on slide 700 is cleaned on slide 700, the cleaning reagent after cleansing tissue sample is discharged by waste suction liquid pipe 492, In order to detect to the cleaning reagent in reagent storage device 480, as shown in figure 13, the present embodiment is additionally provided with reagent Detection device 600, reagent detection device 600 are connected with reagent storage device 480.
The manipulator 400 of the present embodiment further includes top plate 401, the first driving motor 430 and the second driving motor 460 difference Positioned at the upper surface of top plate 401, the first guide rail 410, the second guide rail 420 top be individually fixed in the lower surface of top plate 401, push up A side of plate 401 is equipped with pinboard 402, and pinboard 402 is fixed in mechanical arm drive mechanism 200.
The present embodiment take tube head 450 and liquid feeding portion is four, dyeing and clear can be carried out to four tissue specimens simultaneously It washes, in the application, the quantity for taking tube head 450 and liquid feeding portion can be also increased or decreased according to use demand.
The mechanical arm drive mechanism 200 of the present embodiment is led including third driving motor 210, the 4th driving motor 220, X-axis Rail 230 and Y-axis guide rail 240, third driving motor 210 are connected with Y-axis guide rail 240, and Y-axis guide rail 240 is located at X-axis guide rail 230 On, third driving motor 210 drives Y-axis guide rail 240 to move left and right on X axis rail 230, and manipulator 400 is located at Y-axis guide rail On 240, the 4th driving motor 220 is connected with manipulator 400, and 220 driving manipulator 400 of the 4th driving motor is in Y-axis guide rail It is moved forward and backward on 240.
The advantages of the present embodiment or principle are as follows:
1, transfer dyeing mechanism is connected with the first guide rail 410, and wiper mechanism is connected with the second guide rail 420, transfer dyeing machine Structure and the wiper mechanism two sides that be located at the first guide rail 410, the second guide rail 420 opposite, lead the first guide rail 410 with second Rail 420 may be on same plane, facilitate transfer dyeing mechanism and cleaning machine while reducing the width of manipulator 400 The installation of structure allows manipulator 400 to be made narrow, reduces the installation space of manipulator 400, makes the structure of manipulator 400 It is more succinct;
The manipulator of film-making dyeing all-in-one machine is connected with mechanical arm drive mechanism, and mechanical arm drive mechanism drives manipulator to exist Left and right or back-and-forth motion, are shifted, dyed and are cleaned to the tissue specimen being placed on workbench above workbench, overall process Automatic integratedization operation improves the working efficiency of film-making dyeing all-in-one machine, has saved cost of labor.
2, transfer dyeing mechanism is connected with the first guide rail 410, and wiper mechanism is connected with the second guide rail 420, transfer dyeing machine Structure and the wiper mechanism two sides that be located at the first guide rail 410, the second guide rail 420 opposite, lead the first guide rail 410 with second Rail 420 may be on same plane, facilitate transfer dyeing mechanism and cleaning machine while reducing the width of manipulator 400 The installation of structure allows manipulator 400 to be made narrow, reduces the installation space of manipulator 400, makes the structure of manipulator 400 It is more succinct.
3, two the first guide rails 410 are located at the two sides of the second guide rail 420, the transfer dyeing mechanism on manipulator 400 After wiper mechanism installation, the weight of the two sides of manipulator 400 can achieve the state of relative equilibrium, be convenient for manipulator 400 Movement and control.
4, transfer dyeing mechanism the first driving motor 430 drive the first sliding block mainboard 440 on the first guide rail 410 on Lower movement, the drive of the first sliding block mainboard 440 take tube head 450 to move up and down, tube head 450 are taken to be connected by appendix with air pump 451, The control of air pump 451 takes tube head 450 to draw suction nozzle, and passes through suction nozzle aspirates tissue sample or dye liquor, the transfer of control group price card sheet And dyeing.
5, the negative-pressure detection device 500 on appendix is by the negative pressure transformation in detection appendix, and judges to take pipe with this Whether first 450 draw suction nozzle, tissue specimen and dye liquor etc., prevents that tube head 450 is taken the case where leakage is drawn occur, and improves film-making dyeing The transfer tissue specimen of machine and the accuracy of dyeing.
6, the manipulator 400 of film-making dyeing all-in-one machine is connected with mechanical arm drive mechanism 200, mechanical arm drive mechanism 200 Manipulator 400 left and right or back-and-forth motion above workbench 300 are driven, the tissue specimen being placed on workbench 300 is carried out Transfer, dyeing and cleaning, the operation of overall process automatic integratedization improve the working efficiency of film-making dyeing all-in-one machine, have saved people Work cost.
7, wiper mechanism the second driving motor 460 drive the second sliding block mainboard 470 on the second guide rail 420 on move down Dynamic, the second sliding block mainboard 470 drives liquid feeding portion to move up and down, and liquid feeding portion realizes during moving up and down to tissue specimen Cleaning and discharge cleaning reagent.
8, the cleaning reagent in reagent storage device 480 is entered in liquid-feeding tube 491 by perfusion tube, and cleaning reagent passes through Liquid-feeding tube 491 is expelled in preparation bin 800 and cleans to tissue specimen, and after tissue specimen cleaning, cleaning reagent passes through waste suction Liquid pipe 492 is discharged, and the cleaning of tissue specimen and the discharge of cleaning reagent are relatively simple.
9, the bottom of liquid-feeding tube 491 extends along waste suction liquid pipe 492 to the oblique upper far from waste suction liquid pipe 492, liquid-feeding tube 491 When adding cleaning reagent, cleaning reagent is expelled on the inner wall of preparation bin 800, and then cleaning reagent passes through preparation bin 800 Inside flows on slide 700, prevents the cleaning reagent in liquid-feeding tube 491 to be directly sprayed on slide 700 and breaks up tissue specimen.
10, the bottom of liquid-feeding tube 491 is higher than the bottom of waste suction liquid pipe 492, such to be arranged when cleaning reagent is discharged, and can have Effect prevents cleaning reagent from entering in liquid-feeding tube 491.
11, the cleaning reagent amount in 600 detection reagent detection device of reagent detection device, when cleaning reagent amount is less than After a certain amount of, operator can be reminded to add cleaning reagent.
12, film-making dyes all-in-one machine before operation, suction nozzle is first placed in suction nozzle placement section 350, dye liquor is placed in dye liquor Placement section 320, tissue specimen are placed in sample placement section 310, slide 700 are placed in film-making dyeing portion 330, while in slide Preparation bin 800 is placed on 700, when dyeing machine is run, manipulator 400 is first moved to suction nozzle placement section 350 and draws suction nozzle, so Manipulator 400 drives suction nozzle to be moved to sample placement section 310 and draws a certain amount of tissue specimen, manipulator 400 by suction nozzle afterwards It is moved to film-making dyeing portion 330, tissue specimen is placed in preparation bin 800, then manipulator 400 is moved to dye liquor placement Portion 320 draws a certain amount of dye liquor by suction nozzle, and manipulator 400 is moved to film-making dyeing portion 330 and dye liquor is placed in preparation bin Tissue specimen is dyed in 800, then manipulator 400 is moved to 350 desorption pipe of suction nozzle placement section, after tissue specimen dyeing Manipulator 400 is moved to film-making dyeing portion 330 and cleans to tissue specimen, completes the film-making dyeing and cleaning of tissue specimen, The workbench 300 of film-making dyeing all-in-one machine is arranged relatively reasonable, and stroke is most short optimal in the process of running for manipulator 400, and In film-making dyeing course will not suction nozzle placement section 350, film-making dyeing portion 330, dye liquor placement section 320 and sample placement section 310 it Between will not occur cross contamination, the transfer sample of manipulator 400, specimen staining and cleaning setting it is relatively reasonable.
13, the waste liquid placement section 340 on workbench 300 prevents discarded dye liquor to dye liquor for placing discarded dye liquor The dye liquor of placement section 320 pollutes.
14, for placing suction nozzle, suction nozzle is placed in suction nozzle putting hole 3511 the suction nozzle frame 351 of suction nozzle placement section 350, Absorption convenient for manipulator 400 to suction nozzle, suction nozzle recycling box 352 are used to place contaminated or damage suction nozzle, prevent dirty The suction nozzle of dye or the suction nozzle of damage cause to obscure with the suction nozzle on suction nozzle frame 351.
15, tissue specimen is placed in test tube 314, and the test tube 314 for holding tissue specimen is placed in sample placement plate 312 In test tube putting hole 313, test tube 314 is fixed in test tube putting hole 313, and test tube 314 is effectively prevent to topple over.
16, the first fool proof pin 315 and the first fool proof hole 316 can effectively prevent sample placement plate 312 to be placed in specimen holder 311 Placement mistake in position when upper, the first positioning pin 317 and the realization sample placement plate 312 of first positioning hole 318 are determined with specimen holder 311 Position.
17, the slide 700 on film-making dyed plate 332 is placed as placing slide 700, and the second of film-making dyeing portion 330 It is wrong that fool proof pin 334 and the second fool proof hole effectively prevent film-making dyed plate 332 to be placed in the upper placement location of film-making dyeing support 331 Accidentally, the second positioning pin 335 and second location hole 336 realize the location and installation of film-making dyed plate 332 and film-making dyeing support 331.
18, the leveling portion 337 on film-making dyeing support 331 is for adjusting film-making dyed plate 332 placed thereon It is flat, it places film-making dyed plate 332 and tilts, to influence the dyeing of tissue specimen disposed thereon.
The above are only specific embodiments of the present invention, does not limit the protection scope of the utility model with this;Not It violates made any replacement on the basis of the utility model is conceived and improves, the category protection scope of the utility model.

Claims (26)

1. manipulator, which is characterized in that including transfer dyeing mechanism, wiper mechanism and guide rail mechanism, the guide rail mechanism includes First guide rail and the second guide rail, first guide rail and second guide rail are in same level, the transfer dyeing machine Structure is connected with first guide rail, and the wiper mechanism is connected with second guide rail, the transfer dyeing mechanism and described clear Washing machine structure is located at the opposite two sides of first guide rail, the second guide rail, and first guide rail is two, described in two First guide rail is located at the two sides of second guide rail.
2. manipulator as described in claim 1, which is characterized in that the transfer dyeing mechanism includes the first driving motor, first Sliding block mainboard takes tube head and air pump, and first driving motor is connected with the first sliding block mainboard, the first sliding block mainboard It is described that tube head is taken to be located on the first sliding block mainboard on first guide rail, it is described that tube head one end is taken to be equipped with appendix, The appendix other end is connected with the air pump.
3. manipulator as claimed in claim 2, which is characterized in that the first sliding block mainboard is equipped with and takes tube socket, described to take pipe Head is located at described take on tube socket.
4. manipulator as claimed in claim 3, which is characterized in that be additionally provided with first bearing seat on the first sliding block mainboard, institute The main shaft for stating the first driving motor is connected after the first bearing seat and with the first bearing seat.
5. manipulator as claimed in claim 2, which is characterized in that the appendix is equipped with negative-pressure detection device, the negative pressure Detection device takes between tube head and the air pump described in being located at, and the negative pressure that the negative-pressure detection device detects the appendix becomes Change.
6. manipulator as described in claim 1, which is characterized in that the wiper mechanism includes the second driving motor, the second sliding block Mainboard and liquid feeding portion, second driving motor are connected with the second sliding block mainboard, and the second sliding block mainboard is located at described On second guide rail, the liquid feeding portion is located on the second sliding block mainboard.
7. manipulator as claimed in claim 6, which is characterized in that the second sliding block mainboard is equipped with fixed plate, the liquid feeding Portion is located in the fixed plate.
8. manipulator as claimed in claim 6, which is characterized in that the liquid feeding portion includes liquid-feeding tube and waste suction liquid pipe, it is described plus Liquid pipe is located in the waste suction liquid pipe, and the bottom of the liquid-feeding tube is along the waste suction liquid pipe on oblique far from the waste suction liquid pipe Fang Yanshen, the bottom of the liquid-feeding tube are higher than the bottom of the waste suction liquid pipe.
9. manipulator as claimed in claim 8, which is characterized in that the wiper mechanism further includes reagent storage device, described to add The top of liquid pipe and the waste suction liquid pipe is equipped with perfusion tube, and the one end for the perfusion tube being connected with the liquid-feeding tube and the reagent store up Cryopreservation device is connected.
10. manipulator as claimed in claim 7, which is characterized in that the second sliding block mainboard is equipped with second bearing seat, described Second driving motor is connected with the second bearing seat.
11. manipulator as claimed in claim 9, which is characterized in that the wiper mechanism further includes reagent detection device, institute Reagent detection device is stated to be connected with the reagent storage device.
12. the manipulator as described in any one of claims 1 to 11, which is characterized in that the wiper mechanism is located at the transfer Dye the front side of mechanism.
13. all-in-one machine is dyed in film-making, which is characterized in that including rack, mechanical arm drive mechanism, workbench and such as claim 1 To manipulator described in any one of 12, the manipulator, the mechanical arm drive mechanism and the workbench are located at the machine On frame, the mechanical arm drive mechanism is connected with the manipulator, and the manipulator is located above the workbench.
14. all-in-one machine is dyed in film-making as claimed in claim 13, which is characterized in that the workbench be equipped with sample placement section, Suction nozzle placement section, dye liquor placement section and film-making dyeing portion, the film-making dyeing part are placed in the dye liquor placement section and sample The one end in portion, and the dye liquor placement section, between the suction nozzle placement section and film-making dyeing portion, the sample places position In the side of dye liquor placement section.
15. all-in-one machine is dyed in film-making as claimed in claim 14, which is characterized in that be additionally provided with waste liquid placement on the workbench Portion, the waste liquid placement section is between the suction nozzle placement section and the dye liquor placement section.
16. all-in-one machine is dyed in film-making as claimed in claim 14, which is characterized in that the suction nozzle placement section includes suction nozzle frame and suction Mouth recycling box, the suction nozzle recycling box is located at the side of the suction nozzle frame, and the suction nozzle recycling box is located at sample placement The other end opposite with film-making dyeing portion in portion.
17. all-in-one machine is dyed in film-making as claimed in claim 16, which is characterized in that the suction nozzle frame, which is equipped with, penetrates through the suction nozzle The suction nozzle putting hole of frame.
18. all-in-one machine is dyed in film-making as claimed in claim 14, which is characterized in that the sample placement section includes specimen holder and mark This placement plate, the sample placement plate are equipped with the test tube putting hole for penetrating through the sample placement plate, sample placement plate position In on the specimen holder.
19. all-in-one machine is dyed in film-making as claimed in claim 18, which is characterized in that it is anti-that sample placement plate one end is equipped with first Slow-witted pin, the specimen holder are equipped with the first fool proof hole, and the first fool proof pin is corresponding with first fool proof hole.
20. all-in-one machine is dyed in film-making as claimed in claim 19, which is characterized in that the other end is additionally provided in the sample placement plate First positioning pin, the specimen holder are equipped with first positioning hole, and first positioning pin is corresponding with the first positioning hole.
21. all-in-one machine is dyed in film-making as claimed in claim 14, which is characterized in that film-making dyeing portion includes film-making dyeing branch Frame and film-making dyed plate, the film-making dyed plate are located on the film-making dyeing support, and the film-making dyed plate is equipped with slide Place position.
22. all-in-one machine is dyed in film-making as claimed in claim 21, which is characterized in that it is anti-that film-making dyed plate one end is equipped with second Slow-witted pin, the film-making dyeing support are equipped with the second fool proof hole, and the second fool proof pin is corresponding with second fool proof hole.
23. all-in-one machine is dyed in film-making as claimed in claim 22, which is characterized in that opposite both ends are also on the film-making dyed plate It is respectively equipped with the second positioning pin, the film-making dyeing support is equipped with second location hole, second positioning pin and described second Location hole is corresponding.
24. all-in-one machine is dyed in film-making as claimed in claim 21, which is characterized in that the film-making dyeing support is equipped with leveling Portion, the leveling portion are connected with the film-making dyed plate.
25. all-in-one machine is dyed in film-making as described in any one of claim 13 to 24, which is characterized in that the robot drives machine Structure includes third driving motor, the 4th driving motor, X-axis guide rail and Y-axis guide rail, and the third driving motor is led with the Y-axis Rail is connected, and the Y-axis guide rail is located in the X-axis guide rail, and the manipulator is located in the Y-axis guide rail, the 4th driving Motor is connected with the manipulator.
26. all-in-one machine is dyed in film-making as described in any one of claim 13 to 24, which is characterized in that the rack includes main body Housing cap, the housing cap are connect with the subject activity, and the housing cap is by the manipulator, mechanical arm drive mechanism and work The body interior is wrapped in as platform.
CN201821792601.0U 2018-11-01 2018-11-01 All-in-one machine is dyed in manipulator and film-making with the manipulator Active CN209231070U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110631878A (en) * 2019-10-28 2019-12-31 宁波美生医疗器材有限公司 Sample transfer mechanism of liquid-based cell automatic sheet-making medical equipment

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110631878A (en) * 2019-10-28 2019-12-31 宁波美生医疗器材有限公司 Sample transfer mechanism of liquid-based cell automatic sheet-making medical equipment

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