CN208968871U - A kind of vaporization prevention deoxygenation digestion instrument - Google Patents
A kind of vaporization prevention deoxygenation digestion instrument Download PDFInfo
- Publication number
- CN208968871U CN208968871U CN201821328659.XU CN201821328659U CN208968871U CN 208968871 U CN208968871 U CN 208968871U CN 201821328659 U CN201821328659 U CN 201821328659U CN 208968871 U CN208968871 U CN 208968871U
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- CN
- China
- Prior art keywords
- probe tube
- deoxygenation
- stripping rotor
- stirring
- helium
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Abstract
The utility model provides a kind of vaporization prevention deoxygenation digestion instrument, including base, machine top and control device, the base is equipped with water bath, lifting device and sampling liquid supply device, the lifting device connection base and machine top, stripping rotor is equipped in the water bath, the rim of a cup of the stripping rotor is equipped with vaporization prevention lid, the sampling liquid supply device includes specimen cup, probe tube, sampling pump and liquid supply device, the probe tube connects inside the stripping rotor and inside the specimen cup, the probe tube is equipped with triple valve, the triple valve is connect with the liquid supply device by liquid supplementation pipe, the liquid supplementation pipe is pumped equipped with fluid infusion, stirring-head is equipped with inside the stripping rotor, the stirring-head and described probe tube one end are rotatablely connected, the stirring-head connects rotary electric machine.The beneficial effects of the utility model are: stirring rod and probe tube are unified, while realizing stirring and sampled functions, structure is simple, and manufacturing cost is lower；Setting helium feeding mechanism improves dissolution and examines accuracy to deoxygenation is carried out in stripping rotor.
Description
Technical field
The utility model belongs to medical equipment technical field, more particularly, to a kind of vaporization prevention deoxygenation digestion instrument.
Background technique
Drug dissolution refers to drug in regulation medium, under certain condition, from the solid pharmaceutical preparations such as tablet or capsule
The speed of dissolution and the degree of dissolution.Drug dissolution directly affects the absorption and utilization of drug in vivo, is evaluation medicinal substances
In index in one of amount.In drug production testing, clinical efficacy investigation, stability of drug products inspection, new drug development, prescription sieve
Many aspects such as choosing, process modification will investigate this index.Drug dissolution inspection is evaluation preparation quality and technological level
A kind of effective means, and evaluation agent activity ingredients Biogenic availability and the preparation uniformity a kind of effective standard, can have
Effect distinguishes the difference of same drug bioavailability, therefore is one of drug quality control essential items for inspection.
Summary of the invention
Problem to be solved in the utility model is to provide that a kind of structure is simple, vaporization prevention deoxygenation digestion instrument easy to use.
In order to solve the above technical problems, the technical solution adopted in the utility model is: a kind of vaporization prevention deoxygenation digestion instrument, packet
Base, machine top and control device are included, the base is equipped with water bath, lifting device and sampling liquid supply device, the lifting dress
Connection base and machine top are set, stripping rotor is equipped in the water bath, the rim of a cup of the stripping rotor is equipped with vaporization prevention lid, the sampling
Liquid supply device includes specimen cup, probe tube, sampling pump and liquid supply device, and the probe tube connects inside the stripping rotor and described
Inside specimen cup, the probe tube is equipped with triple valve, and the triple valve is connect with the liquid supply device by liquid supplementation pipe, described
Liquid supplementation pipe is pumped equipped with fluid infusion, and stirring-head is equipped with inside the stripping rotor, and the stirring-head and the rotation of described probe tube one end connect
It connects, the stirring-head connects rotary electric machine, and the sampling pump, fluid infusion pump, rotary electric machine, lifting device are filled with the control respectively
Set electrical connection.
In technical solution, it is preferred that further include helium feeding mechanism, the helium feeding mechanism passes through with the stripping rotor
The connection of helium communicating pipe is equipped with helium supply valve, the helium supply valve and the control device electricity helium communicating pipe
Connection.
In technical solution, it is preferred that the helium communicating pipe is fixedly connected with the machine top.
In technical solution, it is preferred that the probe tube is fixedly connected with the machine top.
In technical solution, it is preferred that be equipped with filter membrane in the probe tube.
In technical solution, it is preferred that the filtering membrane aperture is 0.45 μm.
The utility model has the advantages and positive effects of: it is ingenious in design, stirring rod and probe tube are unified, while real
Now stirring and sampled functions, structure is simple, and manufacturing cost is lower；Helium feeding mechanism is set to deoxygenation is carried out in stripping rotor, is mentioned
Accuracy is examined in height dissolution；The scientific research departments such as universities and colleges, medical treatment, health and epidemic prevention, environmental monitoring, pharmaceutical industry suitable for major
Dissolution rate test.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of an embodiment of the present invention.
Fig. 2 is the schematic diagram of an embodiment of the present invention.
In figure:
1, base 2, machine top 3, control device
4, water bath 5, lifting device 6, stripping rotor
7, vaporization prevention lid 8, specimen cup 9, probe tube
10, sampling pump 11, liquid supply device 12, triple valve
13, liquid supplementation pipe 14, fluid infusion pump 15, stirring-head
16, rotary electric machine 17, helium feeding mechanism 18, helium communicating pipe
19, helium supply valve 20, filter membrane
Specific embodiment
Embodiment 1
As shown in Figure 1, the present embodiment provides a kind of vaporization prevention deoxygenation digestion instrument, including base 1, machine top 2 and control device
3, base 1 is equipped with water bath 4, lifting device 5 and sampling liquid supply device 11, and lifting device 5 connects base 1 and machine top 2, lifting
Device 5 is used to control the lifting on machine top 2, and stripping rotor 6 is equipped in water bath 4, and the rim of a cup of stripping rotor 6 is equipped with vaporization prevention lid 7, sampling
Liquid supply device 11 includes specimen cup 8, probe tube 9, sampling pump 10 and liquid supply device 11, and probe tube 9 connects 6 inside of stripping rotor and sample
Inside product cup 8, probe tube 9 is equipped with triple valve 12, and triple valve 12 is connect with liquid supply device 11 by liquid supplementation pipe 13, liquid supplementation pipe 13
It is equipped with fluid infusion pump 14, stirring-head 15 is equipped with inside stripping rotor 6, stirring-head 15 and 9 one end of probe tube are rotatablely connected, stirring-head 15
Rotary electric machine 16 is connected, sampling pump 10, fluid infusion pump 14, rotary electric machine 16, lifting device 5 are electrically connected with control device 3 respectively.
It further include helium feeding mechanism 17, helium feeding mechanism 17 passes through with stripping rotor 6 to be connect helium communicating pipe 18, helium
Communicating pipe 18 is equipped with helium supply valve 19, and helium supply valve 19 is electrically connected with control device 3.Helium communicating pipe 18 and machine top 2
It is fixedly connected.
Filter membrane 20 is equipped in probe tube 9,20 aperture of filter membrane is 0.45 μm, prevents drug granule from entering probe tube 9, makes
At the deviation of inspection result.
Vaporization prevention lid 7 is equipped with through-hole, probe tube 9, helium communicating pipe 18 is entered inside stripping rotor 6 by through-hole, is passed through
The setting of vaporization prevention lid 7 prevents liquid evaporation in stripping rotor 6, and temperature is kept to stablize.
It is ingenious in design, stirring rod and probe tube 9 are unified, while realizing stirring and sampled functions, structure is simple, manufacture at
This is lower；Setting helium feeding mechanism 17 improves dissolution and examines accuracy to deoxygenation is carried out in stripping rotor 6；Suitable for each big-and-middle
The dissolution rate test of the scientific research departments such as universities and colleges, medical treatment, health and epidemic prevention, environmental monitoring, pharmaceutical industry.
The course of work: in use, opening machine top 2 by lifting device 3, dissolution medium is packed into (usually in stripping rotor 6
Deionized water) and testing drug after, the dissolution rate of testing drug is tested.Start rotary electric machine 16, passes through rotary electric machine
169 drive stirring-head 15, are stirred according to the mixing speed of setting to the dissolution medium in stripping rotor 6, open simultaneously helium
Supply valve 19 is passed through helium into stripping rotor 6, to remove oxygen in stripping rotor 6；When needing to sample, starts sampling pump 10, take
Sample pump 10 is transferred in specimen cup 8 by the pipette samples out of stripping rotor 6 of probe tube 9；When needing fluid infusion, make-up valve is opened,
Dissolution medium in liquid supply device 11 is transferred in stripping rotor 6.
One embodiment of the utility model is described in detail above, but the content is only the utility model
Preferred embodiment should not be considered as limiting the scope of the present invention.It is all to be made according to application scope of the utility model
All the changes and improvements etc., should still belong within the patent covering scope of the utility model.
Claims (6)
1. a kind of vaporization prevention deoxygenation digestion instrument, it is characterised in that: including base, machine top and control device, the base is equipped with
Water bath, lifting device and sampling liquid supply device, the lifting device connection base and machine top, the water bath is interior to be equipped with dissolution
The rim of a cup of cup, the stripping rotor is equipped with vaporization prevention lid, and the sampling liquid supply device includes specimen cup, probe tube, sampling pump and benefit
Liquid device, the probe tube connect inside the stripping rotor and inside the specimen cup, and the probe tube is equipped with triple valve, institute
It states triple valve and is connect with the liquid supply device by liquid supplementation pipe, the liquid supplementation pipe is pumped equipped with fluid infusion, is set inside the stripping rotor
There is stirring-head, the stirring-head and described probe tube one end are rotatablely connected, and the stirring-head connects rotary electric machine, the sampling
Pump, fluid infusion pump, rotary electric machine, lifting device are electrically connected with the control device respectively.
2. vaporization prevention deoxygenation digestion instrument according to claim 1, it is characterised in that: it further include helium feeding mechanism, it is described
Helium feeding mechanism is connect with the stripping rotor by helium communicating pipe, and the helium communicating pipe is equipped with helium supply valve, institute
Helium supply valve is stated to be electrically connected with the control device.
3. vaporization prevention deoxygenation digestion instrument according to claim 2, it is characterised in that: the helium communicating pipe and the machine top
It is fixedly connected.
4. vaporization prevention deoxygenation digestion instrument according to claim 1, it is characterised in that: the probe tube is fixed with the machine top
Connection.
5. vaporization prevention deoxygenation digestion instrument according to claim 1, it is characterised in that: be equipped with filter membrane in the probe tube.
6. vaporization prevention deoxygenation digestion instrument according to claim 5, it is characterised in that: the filtering membrane aperture is 0.45 μm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821328659.XU CN208968871U (en) | 2018-08-17 | 2018-08-17 | A kind of vaporization prevention deoxygenation digestion instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821328659.XU CN208968871U (en) | 2018-08-17 | 2018-08-17 | A kind of vaporization prevention deoxygenation digestion instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN208968871U true CN208968871U (en) | 2019-06-11 |
Family
ID=66752289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821328659.XU Expired - Fee Related CN208968871U (en) | 2018-08-17 | 2018-08-17 | A kind of vaporization prevention deoxygenation digestion instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN208968871U (en) |
-
2018
- 2018-08-17 CN CN201821328659.XU patent/CN208968871U/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190611 Termination date: 20200817 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |