CN208313886U - The flow path system of biosensor analysis instrument - Google Patents
The flow path system of biosensor analysis instrument Download PDFInfo
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- CN208313886U CN208313886U CN201820718639.7U CN201820718639U CN208313886U CN 208313886 U CN208313886 U CN 208313886U CN 201820718639 U CN201820718639 U CN 201820718639U CN 208313886 U CN208313886 U CN 208313886U
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- flow path
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Abstract
The utility model provides a kind of flow path system of biosensor analysis instrument, including buffer pool, waste liquid pool, calibration cup, sample cup, sampling apparatus and reaction unit, sampling apparatus includes sampling needle, quantitative collector, flow valve and the sampling stand for controlling sampling needle movement, three interfaces of flow valve are connected to buffer pool, quantitative collector and sampling needle respectively, reaction unit includes reaction tank and power mechanism, and reaction tank has the reaction tank entrance being connected to buffer pool and the reaction tank being connected to waste liquid pool outlet.The flow path system of biosensor analysis instrument provided by the utility model, sampling needle automatic collection liquid under the driving of sampling stand, quantitative collector realize the quantitative collection to liquid, increase the accuracy of test result；Meanwhile sampling apparatus and reaction unit are connected to buffer pool and waste liquid pool, are realized the automatic cleaning of test front and back, are reduced human cost.
Description
Technical field
The utility model belongs to biological analyser technical field, is to be related to a kind of biosensor analysis more specifically
The flow path system of instrument.
Background technique
Bio-sensing analyzer is that a kind of pair of biological substance is sensitive and its concentration is converted to the instrument that electric signal detects
Device is using biological sensitive materials as recognition component (such as enzyme, antibody, antigen, microorganism, cell, tissue biological active matter
Matter), and the analysis tool that constitutes of rationalization energy converter (such as oxygen electrode, photosensitive tube, field-effect tube) and signal amplifying apparatus or
System, and there is important application in fields such as fermentation process analysis, cell cultivation process analysis, vitro diagnosis assays.
The calibration of existing bio-sensing analyzer and test sample are all that hand-held microsyringe is operated, and is with the naked eye known
It is not quantitative, and every time calibration or sample introduction after will Manual-cleaning sample injector, this whole process is cumbersome, is easy to appear
Mistake, bring maloperation and human error, which is manually operated, largely reduces the performance of the instrument, reduces test knot
The accuracy of fruit and the repeatability used.
Utility model content
The purpose of this utility model is to provide a kind of flow path systems of biosensor analysis instrument, to solve the prior art
Present in calibrated manually using sample injector and test sample caused by test result inaccuracy, instrument asked using poor repeatability technology
Topic.
In order to achieve the above purposes, the technical solution adopted by the utility model is: provides a kind of biosensor analysis instrument
Flow path system, comprising:
Buffer pool, for containing buffer；
Waste liquid pool, for collecting waste liquid；
Cup is calibrated, for containing titer；
Sample cup, for containing sample to be tested；
Sampling apparatus comprising sampling needle, quantitative collector, flow valve and mobile for controlling the sampling needle
Sampling stand, flow valve tool there are three interface, and three interfaces of the flow valve respectively with the buffer pool, described fixed
Amount collector is connected to the sampling needle；And
Reaction unit comprising reaction tank and the power mechanism for controlling liquid flowing in the reaction tank, it is described
Reaction tank has the reaction tank entrance being connected to the buffer pool and the reaction tank being connected to waste liquid pool outlet.
It further, further include sample disk, the calibration cup, the sample cup, the reaction unit and the sampling stand
It is both secured on the sample disk.
Further, the sample disk is in circular ring shape, and the calibration cup, the sample cup, the reaction unit are circumferentially set
In on the sample disk, the sampling stand is fixed at the center of the sample disk.
Further, the power mechanism includes double pump, the double pump have interior pump line and outer pump line, the interior pump line with
The waste liquid pool connection, the outer pump line are connected to the buffer pool.
Further, the power mechanism further includes for the waste liquid in the reaction tank to be pumped into the waste liquid pool
Single pump, single pump are connected to the waste liquid pool and the reaction tank.
Further, the reaction unit further includes that there are three the connector of interface, three interfaces of the connector for tool
It is connected to respectively with waste liquid pool, single pump and the interior pump line.
Further, the flow valve is three-way magnetic valve.
Further, multiple test electrodes are equipped in the reaction tank.
Further, the quantitative collector is syringe pump.
The beneficial effect of the flow path system of biosensor analysis instrument provided by the utility model is: with prior art phase
Than in the flow path system of the utility model biosensor analysis instrument, the sampling needle of sampling apparatus is under the driving of sampling stand
Automatic collection liquid, and sampling apparatus further includes quantitative collector, to realize to the quantitative collection of liquid, increases test result
Accuracy；Meanwhile sampling apparatus and reaction unit are connected to buffer pool and waste liquid pool, realize the automatic of test front and back
Cleaning, reduces human cost.
Detailed description of the invention
It, below will be to embodiment or the prior art in order to illustrate more clearly of the technical scheme in the embodiment of the utility model
Attached drawing needed in description is briefly described, it should be apparent that, the accompanying drawings in the following description is only that this is practical new
Some embodiments of type for those of ordinary skill in the art without any creative labor, can be with
It obtains other drawings based on these drawings.
Fig. 1 is the structural schematic diagram of the flow path system of biosensor analysis instrument provided by the embodiment of the utility model；
Fig. 2 is the structural schematic diagram of sample disk provided by the embodiment of the utility model；
Fig. 3 is the cleaning schematic diagram of the flow path system of biosensor analysis instrument provided by the embodiment of the utility model；
Fig. 4 is the structural schematic diagram of sampling apparatus provided by the embodiment of the utility model.
Wherein, each appended drawing reference in figure:
1- buffer pool；2- waste liquid pool；3- sampling apparatus；31- sampling needle；32- quantitative collector；33- flow valve；4- is anti-
Answer device；41- reaction tank；42- power mechanism；The mono- pump of 421-；422- double pump；Pump line in 4221-；The outer pump line of 4222-；43- connects
Connector；5- sample disk；51- sample cup；52- calibrates cup.
Specific embodiment
In order to which technical problem to be solved in the utility model, technical solution and beneficial effect is more clearly understood, with
Lower combination accompanying drawings and embodiments, the present invention will be further described in detail.It should be appreciated that specific reality described herein
It applies example to be only used to explain the utility model, is not used to limit the utility model.
It should be noted that it can be directly another when element is referred to as " being fixed on " or " being set to " another element
On one element or indirectly on another element.When an element is known as " being connected to " another element, it can
To be directly to another element or be indirectly connected on another element.
It is to be appreciated that term " length ", " width ", "upper", "lower", "front", "rear", "left", "right", "vertical",
The orientation or positional relationship of the instructions such as "horizontal", "top", "bottom" "inner", "outside" is that orientation based on the figure or position are closed
System, is merely for convenience of describing the present invention and simplifying the description, rather than the device or element of indication or suggestion meaning are necessary
It with specific orientation, is constructed and operated in a specific orientation, therefore should not be understood as limiting the present invention.
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance
Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or
Implicitly include one or more of the features.The meaning of " plurality " is two or two in the description of the present invention,
More than, unless otherwise specifically defined.
Also referring to Fig. 1 to Fig. 4, now the flow path system of biosensor analysis instrument provided by the utility model is carried out
Explanation.The flow path system of the biosensor analysis instrument, including for containing buffer buffer pool 1, for containing waste liquid
Waste liquid pool 2, the calibration cup 52 for containing titer, the sample cup 51 for containing sample to be tested, sampling apparatus 3 and anti-
Answer device 4.Sampling apparatus 3 includes sampling needle 31, quantitative collector for acquiring titer, sample to be tested etc., sampling apparatus 3
32, flow valve 33 and sampling stand (not shown), sampling needle 31 move under the action of sampling stand, specifically, sampling needle 31
It can move up and down, rotary motion, or be moved in tri- mutually orthogonal directions of XYZ, to realize from calibration cup 52 and sample
It is sampled in cup 51, and liquid is spat into reaction unit 4.There are three interface, three interfaces point of flow valve 33 for the tool of flow valve 33
It is not connected to buffer pool 1, quantitative collector 32 and sampling needle 31, when cleaning sampling apparatus 3, flow valve 33 is connected to slow first
Fliud flushing pond 1 and quantitative collector 32, quantitative collector 32 suck buffer, and then flow valve 33 is connected to sampling needle 31 and quantitatively adopts
Storage 32, quantitative collector 32 release buffer.Guarantee to be full of buffer in the pipeline of sampling apparatus 3 repeatedly, and will
The liquid of discharge is spat into reaction unit 4, carries out automatic unidirectional cleaning to sampling apparatus 3.Quantitative collector 32 and flow valve 33
Cooperation realize the quantitative collection to titer and sample to be tested, improve the detection accuracy of the instrument.Reaction unit 4 includes
Reaction tank 41 and power mechanism 42, power mechanism 42 are used to control the flowing of the liquid in 4 pipeline of reaction unit, reaction tank 41
Reaction tank entrance be connected to buffer pool 1, the outlet of the reaction tank of reaction tank 41 is connected to waste liquid pool 2, the first general of power mechanism 42
Waste liquid in 4 pipeline of reaction unit is discharged into waste liquid pool 2, and then buffer is pumped into reaction unit 4, so to reaction unit 4
Automatically it is cleaned.
The flow path system of biosensor analysis instrument provided by the utility model, compared with prior art, the utility model
The flow path system of biosensor analysis instrument is provided with sampling apparatus 3, driving of the sampling needle 31 in sampling apparatus 3 in sampling stand
Lower automatic collection liquid, and sampling apparatus 3 further includes quantitative collector 32, to realize to the quantitative collection of liquid, increases survey
The accuracy of test result；Meanwhile sampling apparatus 3 and reaction unit 4 are connected to buffer pool 1 and waste liquid pool 2, realize test
The automatic cleaning of front and back, reduces human cost.
After sampling apparatus 3 and reaction unit 4 clean automatically, auto-scaling is carried out first.Specifically, sampling needle 31
The top of calibration cup 52 is moved under the drive of sampling stand, then flow valve 33 is connected to sampling needle 31, quantitative collector 32
Appropriate air is sucked, with the buffer being isolated in sampling needle 31 and the titer that will be sucked, sampling needle 31 drops to calibration cup
Titer is sucked in 52, quantitative collector 32 sucks appropriate air again, wall built-up dynamics of the titer in sampling needle 31 is improved,
In order to avoid titer is thrown out of when sampling needle 31 moves.Sampling apparatus 3 is back to reaction unit 4 after having acquired titer, by standard
Liquid is spat into reaction tank 41, and reaction tank 41 analyzes titer.Secondly, carrying out test sample after the completion of calibration.Specifically, it samples
Needle 31 is moved to the top of sample cup 51 under the driving of sampling stand, identical as movement when above-mentioned calibration, acquires sample to be tested
And sample to be tested is spat into reaction tank 41 and is tested, repeated washing work is after the completion of test so as to test next time.
Referring to Fig. 2, a kind of specific reality of the flow path system as biosensor analysis instrument provided by the utility model
Mode is applied, which further includes sample disk 5, and calibration cup 52, sample cup 51, reaction unit 4 and sampling stand are both secured to sample
On this disk 5, sampling needle 31 needs to move back and forth between calibration cup 52, sample cup 51, reaction unit 4, and the setting of sample disk 5 is just
In the movement routine for designing and planning sampling needle 31.
Please continue to refer to Fig. 2, a kind of tool of the flow path system as biosensor analysis instrument provided by the utility model
Body embodiment, sample disk 5 are in circular ring shape, and calibration cup 52, sample cup 51, reaction unit 4 are circumferential to be set on sample disk 5, sampling
Frame is fixed at the center of the sample disk 5.When sampling stand control sampling needle 31 is in calibration cup 52, sample cup 51, reaction unit 4
Between when move, sampling stand only needs to make rotating motion, and can so simplify the structure of sampling stand.Certainly, sampling stand controls
Sampling needle 31 is moved upwards in the side XYZ, and the track combination that sampling stand can be mobile for tri- direction XYZ, sample disk 5 is square at this time,
The array distributions such as sample cup 51, calibration cup 52, reaction unit 4 are on sample disk 5.
Fig. 1 and Fig. 3 is please referred to, a kind of tool of the flow path system as biosensor analysis instrument provided by the utility model
Body embodiment, power mechanism 42 include double pump 422, and double pump 422 has interior pump line 4221 and outer pump line 4222, interior pump line 4221
It is connected to waste liquid pool 2, outer pump line 4222 is connected to buffer pool 1.When cleaning reaction unit 4, outer pump line 4222 is by buffer
Buffer in pond 1 is persistently pumped into reaction tank 41, and the liquid overflowed in reaction tank 41 is pumped into waste liquid pool 2 by interior pump line 4221
In, realize the cleaning to reaction unit 4.
Fig. 1 and Fig. 3 is please referred to, a kind of tool of the flow path system as biosensor analysis instrument provided by the utility model
Body embodiment, power mechanism 42 further include single pump 421, and single pump 421 be connected to waste liquid pool 2 and reaction tank 41, single pump 421 with pair
It is parallel with one another to pump 422.Before cleaning reaction unit 4, can pump 421 by list first will be in 4 pipe of reaction tank 41 and reaction unit
Liquid is all discharged into waste liquid pool 2, is then pumped into buffer using double pump 422, realizes effective unidirectional cleaning.
Fig. 1 and Fig. 3 is please referred to, a kind of tool of the flow path system as biosensor analysis instrument provided by the utility model
Body embodiment is equipped with multiple test electrode (not shown)s in reaction tank 41, can the multiple projects of disposable test, realization one
Standing posture test.Testing electrode can be ion electrode, enzyme membrane electrode etc..
Referring to Fig. 4, a kind of specific reality of the flow path system as biosensor analysis instrument provided by the utility model
Mode is applied, quantitative collector 32 is syringe pump.Cost is relatively low for syringe pump, and precision with higher, is suitable for the flow path system
In system.
Fig. 1 and Fig. 3 is please referred to, a kind of tool of the flow path system as biosensor analysis instrument provided by the utility model
Body embodiment, reaction unit 4 further include connector 43, and connector 43 also has that there are three interface, three interfaces of connector 43
Be connected to respectively with waste liquid pool 2, single pump 421 and interior pump line 4221, i.e., connector 43 will single pump 421 and double pump 422 sewer pipe
Connection, and import in waste liquid pool 2 together.Specifically, connector 43 is tee connector.Before cleaning reaction unit 4, pass through
Liquid in 4 pipeline of reaction unit is drained into waste liquid pool 2 by single pump 421, and after the liquid discharge in pipeline, outer pump line 4222 is pumped into slow
The liquid of spilling is discharged into waste liquid pool 2 by fliud flushing, interior pump line 4221.
A kind of specific embodiment of flow path system as biosensor analysis instrument provided by the utility model, flow
Valve 33 is three-way magnetic valve.
The above is only the preferred embodiment of the utility model only, is not intended to limit the utility model, all at this
Made any modifications, equivalent replacements, and improvements etc., should be included in the utility model within the spirit and principle of utility model
Protection scope within.
Claims (9)
1. the flow path system of biosensor analysis instrument characterized by comprising
Buffer pool, for containing buffer；
Waste liquid pool, for collecting waste liquid；
Cup is calibrated, for containing titer；
Sample cup, for containing sample to be tested；
Sampling apparatus comprising sampling needle, quantitative collector, flow valve and the sampling for controlling the sampling needle movement
Frame, flow valve tool there are three interface, and three interfaces of the flow valve respectively with the buffer pool, described quantitatively adopt
Storage is connected to the sampling needle；And
Reaction unit comprising reaction tank and the power mechanism for controlling liquid flowing in the reaction tank, the reaction
Pond has the reaction tank entrance being connected to the buffer pool and the reaction tank being connected to waste liquid pool outlet.
2. the flow path system of biosensor analysis instrument as described in claim 1, it is characterised in that: it further include sample disk, institute
Calibration cup, the sample cup, the reaction unit and the sampling stand is stated to be both secured on the sample disk.
3. the flow path system of biosensor analysis instrument as claimed in claim 2, it is characterised in that: the sample disk is in annulus
Shape, the calibration cup, the sample cup, the reaction unit are circumferentially set on the sample disk, and the sampling stand is fixed on institute
It states at the center of sample disk.
4. the flow path system of biosensor analysis instrument as described in claim 1, it is characterised in that: the power mechanism includes
Double pump, the double pump have interior pump line and outer pump line, and the interior pump line is connected to the waste liquid pool, and the outer pump line delays with described
The connection of fliud flushing pond.
5. the flow path system of biosensor analysis instrument as claimed in claim 4, it is characterised in that: the power mechanism also wraps
Include for by the waste liquid in the reaction tank be pumped into the waste liquid pool it is single pump, single pump and the waste liquid pool and described anti-
Pond is answered to be connected to.
6. the flow path system of biosensor analysis instrument as claimed in claim 5, it is characterised in that: the reaction unit also wraps
Tool is included there are three the connector of interface, three interfaces of the connector respectively with waste liquid pool, single pump and the interior pump
Pipe connection.
7. the flow path system of biosensor analysis instrument as claimed in any one of claims 1 to 6, it is characterised in that: the flow
Valve is three-way magnetic valve.
8. the flow path system of biosensor analysis instrument as claimed in any one of claims 1 to 6, it is characterised in that: the reaction
Multiple test electrodes are equipped in pond.
9. the flow path system of biosensor analysis instrument as claimed in any one of claims 1 to 6, it is characterised in that: described quantitative
Collector is syringe pump.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820718639.7U CN208313886U (en) | 2018-05-15 | 2018-05-15 | The flow path system of biosensor analysis instrument |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820718639.7U CN208313886U (en) | 2018-05-15 | 2018-05-15 | The flow path system of biosensor analysis instrument |
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| CN208313886U true CN208313886U (en) | 2019-01-01 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110218640A (en) * | 2019-03-28 | 2019-09-10 | 中国检验检疫科学研究院 | A kind of aerosol Acquisition Instrument automatic sample micropipette device |
| WO2021027393A1 (en) * | 2019-08-13 | 2021-02-18 | 深圳市康立生物医疗有限公司 | High-speed electrolyte analyzer |
| CN114643241A (en) * | 2020-12-18 | 2022-06-21 | 深圳市帝迈生物技术有限公司 | Liquid supply system and liquid supply method |
-
2018
- 2018-05-15 CN CN201820718639.7U patent/CN208313886U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110218640A (en) * | 2019-03-28 | 2019-09-10 | 中国检验检疫科学研究院 | A kind of aerosol Acquisition Instrument automatic sample micropipette device |
| WO2021027393A1 (en) * | 2019-08-13 | 2021-02-18 | 深圳市康立生物医疗有限公司 | High-speed electrolyte analyzer |
| CN114643241A (en) * | 2020-12-18 | 2022-06-21 | 深圳市帝迈生物技术有限公司 | Liquid supply system and liquid supply method |
| CN114643241B (en) * | 2020-12-18 | 2023-12-01 | 深圳市帝迈生物技术有限公司 | Liquid supply system and liquid supply method |
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