CN207996221U - Degradable heart arter patent ductus plugging device - Google Patents
Degradable heart arter patent ductus plugging device Download PDFInfo
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- CN207996221U CN207996221U CN201521137500.6U CN201521137500U CN207996221U CN 207996221 U CN207996221 U CN 207996221U CN 201521137500 U CN201521137500 U CN 201521137500U CN 207996221 U CN207996221 U CN 207996221U
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Abstract
The utility model discloses a kind of degradable heart arter patent ductus plugging devices, including sequentially connected first plate-like net, tubular reticulum and the second plate-like net, first plate-like net is additionally provided with closing in line, closing in line is arranged in all cyclic annular cables, and the outer wire side of the first plate-like net forms continuous netted face after the closing in of closing in line;Second plate-like net is equipped with connector for wire side to close up, and connector is shaped by the dictyosome hot melt at the center of the second plate-like net, the first plate-like net, tubular reticulum, the second plate-like net and connector material be degradation material.The structure that the utility model plugging device closing in line closes up increases the support force and recovery of plugging device, and reduces manufacture difficulty, reduces manufacturing cost.The utility model not only enables the degradable silk of the discoid net of group be securely attached together, and connector is enable to be securely attached together with the degradable silk for organizing discoid net, it is not easy to fall off.
Description
Technical field
The utility model is related to a kind of degradable heart arter patent ductus plugging devices.
Background technology
Patent ductus arteriosus is one kind in common congenital heart disease, refers to one kind between aorta and pulmonary artery
Birth defect channel, multidigit is between aortic isthmus and left pulmonary artery root.Patent ductus arteriosus is mainly formed in fetus
Growth and development process in, developed due to being affected heart by certain factor, so as to form patent ductus arteriosus.For dynamic
For the patient of arteries and veins patent ductus, blood would generally flow into pulmonary artery by active pulse classic patent ductus arteriosus, into pulmonary circulation
Blood returns again to atrium sinistrum and left ventricle.To cause atrium sinistrum and left ventricular hypertrophy, expansion, left heart failure is eventually led to.If
Catheter diameter is thicker, it is also possible to lead to right ventricle plumpness, dynamic property pulmonary hypertension etc..
Heart arter patent ductus is common congenital heart disease, and traditional therapeutic modality is surgical operation.Surgery hand
The therapy of art, patient need to surgically open chest, and maximum disadvantage is:(1) need extracorporal circulatory system, operation can in art
It can cause complication and lead to death;(2) surgery operating wound is big, and postoperative there are scars;(3) surgery cost is expensive;(4) artery
Patent ductus surgical operation danger when adult and caliber are larger increases.
From the 1980s with intubation intervention diagnosis and the development and raising for the treatment of technology, China is gradually introducing minimally invasive
Interventional technique treats congenital heart disease, is rapidly developed by the method for Minimally Interventional Therapy patent ductus arteriosus, very
It is ripe.Compared to traditional surgery, Minimally Interventional Therapy is a kind of modern high technology minimal invasive treatment.By femoral venous puncture,
Under the guiding of medical imaging device, by guide wire along femoral vein, inferior caval vein until enter right ventricle, by pulmonary artery,
Enter aorta across patent ductus arteriosus.Delivery conduit is then placed in patent ductus arteriosus position along guide wire, finally
By heart arter patent ductus plugging device in pushed in delivery conduit at patent ductus arteriosus implement Occlusion therapy.It is such micro-
Wound interventional treatment have do not operate on, wound is small, few intercurrent disease, restore fast, effect is good, indication range is wide and surgery cost is opposite
More low advantage.
Though having by the therapy of minimally invasive intervention operation implantation patend ductus arteriosus occluder many of the above relative to biography
The advantage for surgical operation of uniting.But due to the material used in the main body rack of the patend ductus arteriosus occluder of present Clinical practice
Material be mainly nitinol alloy wire, since this metalloid material cannot degrade, be chronically implanted can and tissue be inflamed, blood coagulation
Deng reaction, even a degree of damage, therefore there are certain defects, it is possible to there are risks used below:(1)
Nitinol is nondegradable metal alloy compositions, although its biocompatibility is proved, long-term Permanent implantation
Long term risk can not be still perfectly controlled;(2) due to Nitinol Permanent implantation and non-degradable, heart is permanently retained to people
The influence of the safety of body, fixed-size heart occluder to the heart of the continuous growth and development of children still lacks long-term follow-up
Data may influence the growing of the patient's heart of undeveloped mature;(3) complication such as nickel precipitation, nickel allergy are not yet
There is specific scientific appraisal.
On heart occluder surface by complete endothelialization, after heart defect is repaired by body autologous tissue, heart blocks
Necessity that device is not retained in vivo completely.Therefore, ideal heart occluder should provide one for heart itself reparation
Temporary bridge is degraded by body after completing historic mission, defect is made to be repaired completely by autologous tissue, to avoid metal from retaining body
The long term complication and security risk inside brought.
The support construction for the degradable plugging device introduced in United States Patent (USP) US08480709B2 is cut by pipe, is blocked
The tie point of two disks of device is similar with dual welding spots, makes protrusion at two disk centers, can increase plugging device surface local thrombus
The risk of formation is unfavorable for the endothelialization process on plugging device surface, meanwhile, the release of plugging device is made during implant surgery
Length is longer, is easy to damage heart tissue, and the plugging device compliance and recovery that are fabricated to by this method are poor, needs
It is assisted to reply original shape by locking device.
Utility model content
The technical problems to be solved in the utility model is to solve the patend ductus arteriosus occluder of existing Clinical practice
There are problems that long term risk, and overcome the prior art there are the compliance of degradable plugging device and recovery it is poor lack
It falls into, a kind of degradable heart arter patent ductus plugging device is provided.
The utility model is to solve above-mentioned technical problem by following technical proposals:
A kind of degradable heart arter patent ductus plugging device, feature are comprising sequentially connected 1 first
Plate-like net, a tubular reticulum and one second plate-like net, the first plate-like net are the double-deck guard, and the second plate-like net is monolayer net
Cover, the both ends of the tubular reticulum are connected to the interior wire side of the first plate-like net and the second plate-like net, and described first
Plate-like net, the tubular reticulum and the second plate-like net are integrally formed;It is equipped at the center of the second plate-like net for inciting somebody to action
The connector that wire side closes up, the connector are shaped by the dictyosome hot melt at the center of the second plate-like net, and described the
One plate-like net, tubular reticulum, the second plate-like net and connector material be degradation material.
Preferably, the first plate-like net includes a closing in end, the closing in end is the cyclic annular cable of multiple adjoinings successively,
The first plate-like net is additionally provided with a closing in line, and the closing in line is arranged in all cyclic annular cables, through the closing in line
The outer wire side of the first plate-like net forms the netted face of continuous formation after closing in.In this way so that outer net face is more smooth, Ke Yizeng
Add the support force and recovery of plugging device, it is possible to reduce the risk that plugging device surface local thrombus is formed is conducive to accelerate to block
The endothelialization process on device surface makes at heart arter patent ductus being repaired by autologous tissue earlier.Meanwhile reducing and performing the operation
The release length of plugging device, can be greatly reduced the damage to heart in journey, keep operation more effective, safer.
Preferably, the connector is tubulose, the height of the connector is 1.5-2.0mm.In this way so that the second plate-like
There is enough intensity at the closing in of net.If the height of connector is too small, the thread turns inside connector is very few, can cause with
Transport system connects insecure and there are the risks that plugging device falls off., whereas if the height of connector is excessive, closure can be increased
The risk that device surface local thrombus is formed can cause the side plugging device superficial cell climbing with connector slower, extend envelope
The endothelialization process on stifled device surface.Meanwhile making the release length of plugging device longer during implant surgery, it is easy to damage the heart
Dirty tissue.
Preferably, the outer diameter of the connector is 2.5-3.2mm.In this way so that having at the closing in of the second plate-like net enough
Intensity.In addition, if connector outer diameter is too small, it is easy to cause the degradation being connect with connector during connecting member forming
Fracture occurs for silk or bonding strength declines., whereas if connector outer diameter is excessive, the applicable conveying sheath of plugging device can be reduced
The size range of pipe, and it is unfavorable for push of the plugging device in delivery sheath.
Preferably, the second plate-like net is recessed towards at the connector.The wire side of recess can make plugging device from defeated
Sending has preferable elastic recovery after being discharged in sheath, to stably and firmly be plugged at patent ductus arteriosus.
Preferably, the outer diameter of the first plate-like net is bigger 5.5-6.5mm than the outer diameter of the second plate-like net.First plate-like
Net is located at aorta side, and the second plate-like net is located at pulmonary artery side, and for the patient of patent ductus arteriosus, blood would generally be by
Active pulse classic patent ductus arteriosus flows into pulmonary artery, so this structure makes the first plate-like net positioned at aorta side with larger
Support force, the impact of blood flow can be resisted, to make plugging device is stronger to be clamped at patent ductus arteriosus, realized effective
Closure.
Preferably, the length of the tubular reticulum is 4.5-6.5mm.This length can be with the length phase at patent ductus arteriosus
It adapts to, makes plugging device that can firmly be clamped at patent ductus arteriosus, effective Transcatheter Closure of Patent Ductus Arteriosus will not influence
The flowing of blood in pulmonary artery.
Preferably, the one first plate-like net, a tubular reticulum, one second plate-like net and the connector material be
High molecular degradable silk.Biodegradable polymer material be polylactic acid, polyglycolic acid, polycaprolactone, polydioxanone,
One kind in poly butyric ester, polyanhydride, polyphosphate, polyurethane, makrolon or at least two copolymer.These materials
Material has good biocompatibility, can be fully absorbed in human body, avoids long-term influence of the implantation foreign matter on human body.This
Kind of plugging device only provides a temporary bridge for cardiac repair, is degraded by body after completion historic mission, make defect completely by
Autologous tissue repairs, the long term complication to avoid metal retention from bringing in vivo and security risk.
Preferably, the connector is tubulose, the connector is equipped with internal thread in the end opposite with the dictyosome.It is logical
The connector for crossing this helicitic texture, it is more secured with the connection of transport system, can plugging device easily be passed through into transport system
It is transported at patent ductus arteriosus.
A kind of webmaster weaving method includes being inserted into pin in the pinhole of mould stick, degradable silk is penetrated sewing needle needle
Hole knots and closely connects.Starting point is closely knotted with degradable silk, and the intersection point of uplink and downlink is marked with center when braiding
Point alignment is remembered, with the trend of specification silk.Woven webmaster carries out thermal finalization together with mould stick.After stereotyped, pin is pulled out,
Remove webmaster.This weaving method keeps the grid of webmaster more uniform, easily operated, reduces the production cost.
A kind of production method of connector, making step include:
Step 1 closes up to webmaster;
Webmaster is put into mold by step 2;
Step 3, finishing dictyosome;
Step 4, the degradable silk of heating;
Step 5, molding connector shape and internal whorl;
Step 6 removes dictyosome;
Preferably, in step 1, the closing in end margin length of webmaster is first adjusted, edge is made to be aligned, closed up with degradable silk.
Preferably, in step 2, the webmaster that will have been closed up passes through the casing in mold.
Preferably, in step 3, stays a part to be used for making connector in original assembly length, remove the extra of webmaster
Length.
Preferably, in step 4, temperature control device is opened, adjusts temperature, against the degradable silk at connector above mold
Continuous heating, wherein adjustment temperature is 5-15 seconds continuous heating time, to add 40 DEG C -100 DEG C on high molecular polymer fusing point
In thermal process, over-heating can cause the other parts of dictyosome to heat together, destructurized so as to cause dictyosome, and greatly
The material molecule amount for reducing connector part, can cause material premature breakdown.Conversely, heating is insufficient, can cause at connector
Degradable silk can not fully heat and be integrated, complete connector internal thread structure can not be formed, cause connector with it is defeated
Send the bonding strength of system inadequate.Therefore, it is necessary to suitable acid extractions could complete to heat.
Preferably, in step 5, after continuous heating, the degradable silk of connector part is fused together, and removes temperature control dress
It sets, the sliding block being then shut off in mold, and the thread head of mold is inserted into the slot above mold, kept for a period of time.
Preferably, in step 6, after cooling, the thread head rotation of mold is removed into mold, and sliding block is slowly removed,
Dictyosome is removed into mold.
The production method of this connector is easily operated, can obtain the connector of dimensionally stable, and reduces plugging device
On using material type, so that a degradable silk for the discoid net of group is securely attached to together, and make connector and composition
The degradable silk of plate-like net can be securely attached to together, it is not easy to be fallen off.
A kind of dictyosome method for shaping includes that the dictyosome with connector is packed into dictyosome shaper, is used in combination fixture solid
It is fixed, it is carried out thermal finalization together, after stereotyped, dictyosome is removed from the molds.Degradable membrane is packed into dictyosome with suture,
And it is a smooth disk at closing in end close up.This dictyosome method for shaping is easily operated, and the occluder size of making is stablized,
There is larger support force and preferable recovery of shape by the plugging device that this kind of method makes, meet the requirement of surgical procedure,
Keep operation more effective, safer.
The positive effect of the utility model is:
The utility model plugging device is knitted to form by high molecular degradable silk, and biodegradation period is 6 months to 2 years,
It can be fully absorbed in human body, avoid long-term influence of the implantation foreign matter on human body.It is degradable used in the utility model
Or the absorbable material of human body, it is non-toxic to humans, there is good biocompatibility.The choked flow film of plugging device is biology
Degradable membrane, biodegradation period are 6 months to 2 years, and degradation in vivo after it treats mission is completed in human body and is disappeared, nothing
Retained foreign body.Dictyosome at the center of the second plate-like net is connector by high temperature sweat soldering, specifically, by the
Dictyosome at the center of two plate-like nets heats at high temperature, is used in combination mold that heat-fused portion dictyosome is shaped into connector, makes in this way
The degradable silk of the discoid net of group is not easy to scatter, and can be securely attached together;Simultaneously so that connector and the discoid net of group
Degradable silk can be securely attached together, it is not easy to fall off.The wire side of connector is not installed with using the closing in of closing in line
Structure so that outer wire side is more smooth, can increase the support force and recovery of plugging device, it is possible to reduce plugging device surface part blood
The risk that bolt is formed is conducive to the endothelialization process for accelerating plugging device surface, make arterial duct defect point earlier by itself group
Knit reparation.Meanwhile reducing the release length of plugging device in surgical procedure, the damage to heart can be greatly reduced, make operation more
Effectively, safer;In addition, this plugging device also has the advantages that manufacturing cost is low.
Description of the drawings
Fig. 1 is the plugging device dimensional structure diagram of the utility model preferred embodiment.
Fig. 2 is the plugging device connector schematic diagram of the utility model preferred embodiment.
Fig. 3 is the A direction views in Fig. 1.
Fig. 4 is partial enlargement signal at the closing in end of the outer wire side of the first plate-like net of the utility model preferred embodiment
Figure.
Fig. 5 is the mould stick structural schematic diagram of the utility model preferred embodiment.
Fig. 6 is that the braiding of the webmaster of the utility model preferred embodiment threads schematic diagram.
Fig. 7 is the closing in end expanded schematic diagram of the webmaster of the utility model preferred embodiment.
Specific implementation mode
A preferred embodiment is named, and completely illustrates the utility model in conjunction with attached drawing to become apparent from.
As shown in Figure 1, Figure 2, Figure 3, Figure 4, a kind of degradable heart arter patent ductus plugging device comprising connect successively
The first plate-like net 10, tubular reticulum 30 and the second plate-like net 20 connect, the first plate-like net 10 are the double-deck guard, and the second plate-like net 20 is
The both ends of single layer guard, tubular reticulum 30 are connected to the interior wire side 11 and the second plate-like net 20 of the first plate-like net 10, the first disk
Shape net 10, tubular reticulum 30 and the second plate-like net 20 are integrally formed;It is equipped at the center of second plate-like net 20 and wire side closes up
Connector 40 connects between second plate-like net 20 and connector 40 for sweat soldering;The outer wire side 12 of first plate-like net 10 includes
Closing in end 13, closing in end 13 are the cyclic annular cable 14 of multiple adjoinings successively, and the first plate-like net 10 is additionally provided with closing in line 15, closing in line
15 are arranged in all cyclic annular cables 14, and the outer wire side 12 of first plate-like net 10 forms continuous netted after the closing in of closing in line 15
Face.First plate-like net 10, tubular reticulum 30, the second plate-like net 20 and connector 40 material be degradation material.
Dictyosome of the plugging device of the utility model at the center of the second plate-like net 20 is connection by high temperature sweat soldering
Part is used in combination mold by heat-fused portion net specifically, being heated at high temperature by the dictyosome at the center to the second plate-like net 20
Body-shaping makes the degradable silk of the discoid net of group be not easy to scatter, can be securely attached together in this way at connector 40;Together
When so that connector 40 can be securely attached together with the degradable silk for organizing discoid net, it is not easy to be fallen off.
Connector 40 is tubulose, is highly 1.5-2.0mm, outer diameter 2.5-3.2mm.The interior wire side 11 of first plate-like net 10
It is recessed at towards tubular reticulum 30, the second plate-like net 20 is recessed towards at connector 40.The outer diameter of first plate-like net 10 is than the second plate-like net
The 20 big 5.5-6.5mm of outer diameter;The length of tubular reticulum 30 is 4.5-6.5mm.Connector 40 be tubulose, connector 40 with connect
The opposite end of wire side 20 be equipped with internal thread.
First plate-like net 10, tubular reticulum 30 and the material of the second plate-like net 20 and connector 40 are high molecular degradable
Silk.Biodegradable polymer material is polylactic acid, polyglycolic acid, polycaprolactone, polydioxanone, polyhydroxybutyrate
One kind in ester, polyanhydride, polyphosphate, polyurethane, makrolon or at least two copolymer.It can be filled in plugging device poly-
Lactic acid film is to play the role of stopping blood flow.
The utility model connector is to be heated by degradable silk, and need to meet use condition, not only structure
It excessive cannot cause to hinder push of the plugging device in delivery sheath, also to avoid because of not caused enough the connector of bonding strength
It pulls.
Table 1, connector size, anti-pulling-out force and the push test table in delivery sheath
| Height mm | Outer diameter mm | Anti- pulling-out force N | Whether obstruction pushes | |
| 1 | 2.0 | 1.8 | 6 (weak) | It does not hinder |
| 2 | 2.0 | 2.0 | 11 (weak) | It does not hinder |
| 3 | 2.0 | 2.5 | 25 (strong) | It does not hinder |
| 4 | 1.5 | 2.5 | 20 (strong) | It does not hinder |
| 5 | 1.8 | 2.8 | 31 (strong) | It does not hinder |
| 6 | 1.5 | 3.0 | 34 (strong) | It does not hinder |
| 7 | 2.0 | 3.2 | 41 (strong) | It does not hinder |
| 8 | 2.0 | 3.5 | 52 (strong) | It hinders |
It is found in test, ensures that connector will not be pulled in use when anti-pulling-out force reaches 15N.Pass through upper table
It can be seen that the size of connector directly influences whether plugging device can normally apply among operation in 1.Connector
Inappropriate size design connector can be caused to be pulled, or cannot be introduced into delivery sheath and pushed, these all can
Cause product that can not use.
The first mesh-covered tray of this plugging device is continuous netted face, is closed up using closing in line between cable so that outside first
Dropbox is the wire side of flat smooth, and no protrusion, which is conducive to the reply of stopper shapes and support force improves, and more conducively adds
The endothelialization process on fast plugging device surface, makes heart defect be repaired earlier by autologous tissue.The plugging device of the utility model exists
It is connector that dictyosome at the center of second plate-like net, which passes through high temperature sweat soldering, specifically, by the second plate-like net
Dictyosome at center heats at high temperature, is used in combination mold that heat-fused portion dictyosome is shaped into connector, makes the discoid net of group in this way
Degradable silk be not easy to scatter, can be securely attached together;Simultaneously so that connector and the degradable silk for organizing discoid net
It can be securely attached together, it is not easy to fall off.
Webmaster molding is mainly passed through in the making of the utility model plugging device, connector makes, dictyosome is shaped and polylactic acid membrane
Sew several steps.
When webmaster weaves, pin is inserted into the pinhole 51 such as the mould stick 5 of Fig. 5, degradable silk is penetrated into sewing needle needle
Hole knots and closely connects.The threading rule of braiding as shown in fig. 6, including connector manufacturing terminal D, closing in end B (after molding at
For closing in end 13) and starting point C.It is closely knotted with degradable silk at starting point C, intersection point and the center of uplink and downlink when braiding
Point alignment is marked, with the trend of specification silk.Woven webmaster carries out thermal finalization together with mould stick.After stereotyped, pin is pulled out
Son removes webmaster.
Connector making step includes:
1, it closes up to webmaster;
2, webmaster is put into mold;
3, dictyosome is modified;
4, degradable silk is heated;
5, connector shape and internal whorl are molded;
6, dictyosome is removed;
Wherein, in step 1, the closing in end margin length of webmaster is first adjusted, edge is made to be aligned, closed up with degradable silk, tool
The closing in mode of body is as shown in fig. 7, including pin mark 61 and entry point 62 is gone out, the sequence of threading goes out pin mark according in Fig. 7
61 and entry point 62 close up.In step 2, the webmaster that will have been closed up passes through the casing in mold.In step 3, in original
Have stays a part to be used for making connector in assembly length, removes the additional length of webmaster.In step 4, temperature control device is opened, is adjusted
Whole temperature, against the degradable silk continuous heating at connector above mold.In step 5, after continuous heating, connector portion
The degradable silk divided is fused together, and removes temperature control device, the sliding block being then shut off in mold, and the thread head of mold is inserted into
In slot above mold, kept for a period of time.In step 6, after cooling, the thread head rotation of mold is removed into mold, and
Sliding block is slowly removed, dictyosome is removed into mold.
In addition, in step 4, adjustment temperature is continuous heating time 5- 40 DEG C -100 DEG C on high molecular polymer fusing point
15 seconds.Shown in table 2- tables 4 specific as follows, in heating process, over-heating can cause the other parts of dictyosome to heat together, to
Cause dictyosome destructurized, and greatly reduce the material molecule amount of connector part, to which material premature breakdown can be caused.
Conversely, heating is insufficient, it can cause the degradable silk at connector that can not fully heat and be integrated, can not be formed complete
Connector internal thread structure causes the bonding strength of connector and transport system inadequate.Therefore, it is necessary to suitable heating temperature and
Time could complete to heat.
Table 2, L- lactide/glycolides (82/18) degradation material hot melt test table
| Heating time s | Heating temperature DEG C | Connector heats situation | Other parts heat situation | |
| 1 | 2 | 240 | It does not heat fully | It does not heat |
| 2 | 15 | 170 | It does not heat fully | It does not heat |
| 3 | 5 | 240 | Fully hot melt | It does not heat |
| 4 | 5 | 180 | Fully hot melt | It does not heat |
| 5 | 15 | 240 | Fully hot melt | It does not heat |
| 6 | 15 | 180 | Fully hot melt | It does not heat |
| 7 | 5 | 250 | Fully hot melt | Part holt melt |
| 8 | 20 | 180 | Fully hot melt | Part holt melt |
Table 3, polydioxanone degradation material hot melt test table
Table 4, L- lactides/caprolactone (70/30) degradation material hot melt test table
| Heating time s | Heating temperature DEG C | Connector heats situation | Other parts heat situation | |
| 1 | 2 | 210 | It does not heat fully | It does not heat |
| 2 | 15 | 140 | It does not heat fully | It does not heat |
| 3 | 5 | 210 | Fully hot melt | It does not heat |
| 4 | 5 | 150 | Fully hot melt | It does not heat |
| 5 | 15 | 210 | Fully hot melt | It does not heat |
| 6 | 15 | 150 | Fully hot melt | It does not heat |
| 7 | 5 | 220 | Fully hot melt | Part holt melt |
| 8 | 20 | 150 | Fully hot melt | Part holt melt |
Dictyosome sizing includes dictyosome upper mold and dictyosome heat treatment shaping.When dictyosome upper mold, the aforementioned net with connector
Body is packed into dictyosome shaper, and fixture is used in combination to fix, it is carried out thermal finalization together, after stereotyped, by dictyosome from mold
It takes out.Polylactic acid membrane is packed into dictyosome with suture, and it is a smooth disk at closing in end close up.
In the description of the present invention, it should be understood that term "upper", "lower", "front", "rear", "left", "right",
The orientation or positional relationship of the instructions such as "vertical", "horizontal", "top", "bottom", "inner", "outside" be orientation based on ... shown in the drawings or
Position relationship is merely for convenience of describing the present invention and simplifying the description, and does not indicate or imply the indicated device or member
Part must have a particular orientation, with specific azimuth configuration and operation, therefore should not be understood as limiting the present invention.
Although the foregoing describe specific embodiment of the present utility model, it will be appreciated by those of skill in the art that
This is merely illustrative of, and the scope of protection of the utility model is defined by the appended claims.Those skilled in the art
Under the premise of without departing substantially from the principles of the present invention and essence, many changes and modifications may be made,
But these change and modification each fall within the scope of protection of the utility model.
Claims (9)
1. a kind of degradable heart arter patent ductus plugging device, which is characterized in that it includes sequentially connected 1 first disk
Shape net, a tubular reticulum and one second plate-like net, the first plate-like net are the double-deck guard, and the second plate-like net is monolayer net
Cover, the both ends of the tubular reticulum are connected to the interior wire side of the first plate-like net and the second plate-like net, and described first
Plate-like net, the tubular reticulum and the second plate-like net are integrally formed;It is equipped at the center of the second plate-like net for inciting somebody to action
The connector that wire side closes up, the connector are shaped by the dictyosome hot melt at the center of the second plate-like net, and described the
One plate-like net, tubular reticulum, the second plate-like net and connector material be degradation material.
2. degradable heart arter patent ductus plugging device as described in claim 1, which is characterized in that first plate-like
Net includes a closing in end, and the closing in end is the cyclic annular cable of multiple adjoinings successively, and the first plate-like net is additionally provided with a closing in
Line, the closing in line are arranged in all cyclic annular cables, the outer net of the first plate-like net after closing in line closing in
Face forms the netted face of continuous formation.
3. degradable heart arter patent ductus plugging device as described in claim 1, which is characterized in that the connector is
The height of tubulose, the connector is 1.5-2.0mm.
4. degradable heart arter patent ductus plugging device as claimed in claim 3, which is characterized in that the connector
Outer diameter is 2.5-3.2mm.
5. degradable heart arter patent ductus plugging device as described in claim 1, which is characterized in that second plate-like
Net is recessed towards at the connector.
6. degradable heart arter patent ductus plugging device as described in claim 1, which is characterized in that first plate-like
The outer diameter of net is bigger 5.5-6.5mm than the outer diameter of the second plate-like net.
7. degradable heart arter patent ductus plugging device as described in claim 1, which is characterized in that the tubular reticulum
Length is 4.5-6.5mm.
8. degradable heart arter patent ductus plugging device as described in claim 1, which is characterized in that first plate-like
Net, the tubular reticulum, the second plate-like net and the connector material be high molecular degradable silk.
9. degradable heart arter patent ductus plugging device as described in claim 1, which is characterized in that the connector is
Tubulose, the connector are equipped with internal thread in the end opposite with the wire side to connect.
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521137500.6U CN207996221U (en) | 2015-12-31 | 2015-12-31 | Degradable heart arter patent ductus plugging device |
| PCT/CN2016/078756 WO2017113531A1 (en) | 2015-12-31 | 2016-04-08 | Degradable occluder |
| JP2018553276A JP6752289B2 (en) | 2015-12-31 | 2016-04-08 | Disassembleable occluder |
| US16/066,399 US11337683B2 (en) | 2015-12-31 | 2016-04-08 | Degradable occluder |
| EP16880339.3A EP3398533A4 (en) | 2015-12-31 | 2016-04-08 | Degradable occluder |
| SG11201805561SA SG11201805561SA (en) | 2015-12-31 | 2016-04-08 | Degradable occluder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521137500.6U CN207996221U (en) | 2015-12-31 | 2015-12-31 | Degradable heart arter patent ductus plugging device |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110432935A (en) * | 2019-08-01 | 2019-11-12 | 上海形状记忆合金材料有限公司 | Degradable plugging device and preparation method thereof |
| CN112932588A (en) * | 2021-02-01 | 2021-06-11 | 上海锦葵医疗器械股份有限公司 | Degradable heart artery duct patent occluder and manufacturing method thereof |
| CN113558834A (en) * | 2021-08-09 | 2021-10-29 | 广东脉搏医疗科技有限公司 | Connecting assembly for cardiovascular implants |
-
2015
- 2015-12-31 CN CN201521137500.6U patent/CN207996221U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110432935A (en) * | 2019-08-01 | 2019-11-12 | 上海形状记忆合金材料有限公司 | Degradable plugging device and preparation method thereof |
| CN112932588A (en) * | 2021-02-01 | 2021-06-11 | 上海锦葵医疗器械股份有限公司 | Degradable heart artery duct patent occluder and manufacturing method thereof |
| CN113558834A (en) * | 2021-08-09 | 2021-10-29 | 广东脉搏医疗科技有限公司 | Connecting assembly for cardiovascular implants |
| CN113558834B (en) * | 2021-08-09 | 2024-04-26 | 广东脉搏医疗科技有限公司 | Connection assembly for cardiovascular implant |
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Address after: 15th Building, 388 Yindu Road, Xuhui District, Shanghai, 200231 Patentee after: Shanghai Jinkui Medical Devices Co., Ltd. Address before: Room 102, D Workshop, 1618 Yishan Road, Minhang District, Shanghai, 201103 Patentee before: Shanghai Jinkui Medical Implements Co., Ltd. |
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