CN205433769U - Degradable heart ventricular septal defect plugging device - Google Patents
Degradable heart ventricular septal defect plugging device Download PDFInfo
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- CN205433769U CN205433769U CN201620007911.1U CN201620007911U CN205433769U CN 205433769 U CN205433769 U CN 205433769U CN 201620007911 U CN201620007911 U CN 201620007911U CN 205433769 U CN205433769 U CN 205433769U
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Abstract
The utility model discloses a degradable heart ventricular septal defect plugging device, it is double guard with second disc net including first disc of connecting gradually net, tubulose net and second disc net, first disc net, and the both ends of tubulose net are connected respectively in the interior wire side of first disc net and the outer wire side of second disc net, and first disc net, tubulose net and second disc are netted and are integrated into one piece, the connecting piece that is used for the wire side binding off is located to be equipped with in the interior wire side center of second disc net, and the outer wire side center department of first disc net is equipped with the connector that is used for the wire side binding off, the material of first disc net, tubulose net, second disc net and connecting piece is the degradation material, is the height of tubulose net 3.5 9.5mm. The utility model discloses not only make the degradable silk of constituteing the disc net firmly link together, make the connecting piece and the degradable silk of constitution disc net firmly link together moreover, be difficult to drop.
Description
Technical field
This utility model relates to a kind of degradable cardiac ventricular septal defect closer.
Background technology
Ventricular septal defect is the one in common congenital heart disease.Human heart is constituted (left atrium, left ventricle, right atrium and right ventricle) by four chambers, should have a complete interventricular septum between left ventricle and right ventricle, if there being opening the most referred to as ventricular septal defect on cardiac septum.Ventricular septal defect is mainly formed in the growth and development process of fetus, is grown owing to be have impact on heart by certain factor, thus defines ventricular septal defect.For the patient of ventricular septal defect, blood would generally be flow to right ventricle by left ventricle through ventricular septal defect, makes the blood volume of right ventricle increase.The diseases such as the long-term existence of ventricular septal defect can cause pulmonary artery pressure to increase, congestive heart failure, cardiopalmus, asthma, weak, recurrent pulmonary infection.The thickness of the apex in cardiac septum face from top to bottom is by thin thickening, and the relatively thin part of cardiac septum is in cardiac septum film portion, and the thicker part of cardiac septum is cardiac septum pars muscularis.
Ventricular septal heart defect is common congenital heart disease, and traditional therapeutic modality is surgical operation.Operating Therapeutic Method, patient need to surgically open breast, and the shortcoming of its maximum is: needs extracorporeal circulation, operation to be likely to result in complication and cause death in (1) art;(2) surgery operating wound is big, postoperative leaves cicatrix;(3) surgery cost is expensive.
From the eighties in 20th century along with intubation intervention diagnosis and the development for the treatment of technology and raising, China is gradually introducing Wicresoft's interventional technique treatment congenital heart disease, is developed rapidly by the method for Minimally Interventional Therapy ventricular septal defect, the most highly developed.Compare traditional surgery, Minimally Interventional Therapy is a kind of modern high technology invasive treatment, pass through femoral venous puncture, guide wire is used to set up arteriovenous track under the guiding of medical imaging device, subsequently delivery conduit is placed in ventricular septal defect position along guide wire, ventricular septal defect finally pushes to implement at ventricular septal defect in delivery conduit Occlusion therapy.Such Minimally Interventional Therapy have do not operate on, the advantage such as wound is little, few intercurrent disease, recovery is fast, effective, indication scope is wide and surgery cost is relatively low.
Though the Therapeutic Method being got involved operation implantation ventricular septal defect by Wicresoft has the many of the above advantage relative to traditional surgery.But, material used by the main body rack of the ventricular septal defect of present Clinical practice is mainly nitinol alloy wire, owing to this metalloid material can not be degraded, it is chronically implanted the reaction such as meeting and tissue be inflamed, blood coagulation, the most a certain degree of damage, therefore there is certain defect, it is possible to there is risk used below in it: (1) Nitinol is nondegradable metal alloy compositions, although its biocompatibility is proved, but the long term risk of long-term Permanent implantation still cannot be perfectly controlled;(2) due to Nitinol Permanent implantation and non-degradable, forever retaining heart and the impact of the safety of human body, the heart of fixed-size heart occluder growth promoter continuous on child is still lacked long-term Follow-up Data, it may affect the growing of patient's heart of undeveloped mature;(3) complication such as nickel precipitation, nickel allergy do not have clear and definite scientific appraisal yet.
On heart occluder surface by complete endothelialization, after heart defect is repaired by body autologous tissue, heart occluder is entirely without the necessity retained in vivo.Therefore, preferable heart occluder should be to repair for heart self to provide a temporary bridge, is degraded by body, makes defect be repaired by autologous tissue completely, thus avoid metal to retain the internal long term complication brought and potential safety hazard after completing historic mission.
The supporting construction of the degradable stopper introduced in United States Patent (USP) US08480709B2 is formed by pipe cutting, the junction point of two cards of stopper is similar with dual welding spots, make two card centers protruding, the risk that stopper surface local thrombus is formed can be increased, it is unfavorable for the endothelialization process on stopper surface, simultaneously, the release length making stopper during implant surgery is longer, easily impair cardiac tissue, and the stopper compliance being fabricated to by this method and recovery are poor, need to assist it to reply original shape by locking device.
Utility model content
The technical problems to be solved in the utility model is to solve the problem that the ventricular septal defect of existing Clinical practice exists long term risk, and overcome prior art to there is the compliance of degradable stopper and the defect that recovery is poor, it is provided that a kind of degradable cardiac ventricular septal defect closer.
This utility model is to solve above-mentioned technical problem by following technical proposals:
A kind of degradable cardiac ventricular septal defect closer, its feature is, it includes one first plate-like net, a tubular reticulum and the one second plate-like net being sequentially connected with, described first plate-like net and described second plate-like net are double-deck guard, the two ends of described tubular reticulum are connected to interior wire side and the outer wire side of described second plate-like net of described first plate-like net, and described first plate-like net, described tubular reticulum and described second plate-like net are formed in one;The interior wire side center of described second plate-like net is provided with the connector for being closed up by wire side, and described connector is shaped by the dictyosome hot melt of the interior wire side center of described second plate-like net and forms;Described connector is provided with female thread in the end relative with the wire side connected;The outer wire side center of described first plate-like net is provided with the union joint for being closed up by wire side, and described union joint is shaped by the dictyosome hot melt of the outer wire side center of described first plate-like net and forms;The material of described first plate-like net, tubular reticulum, the second plate-like net and connector is degradation material, and the height of described tubular reticulum is 3.5-9.5mm.
It is preferred that described connector is tubulose, the height of described connector is 1.5-2.0mm.So make there is enough intensity at the interior wire side closing in of the second plate-like net.If the height of connector is too small, the thread turns within connector is very few, can cause and be connected insecure with induction system and there is the risk that stopper comes off.Whereas if the height of connector is excessive, the risk that stopper surface local thrombus is formed can be increased, the side stopper superficial cell climbing with connector can be caused relatively slow, extend the endothelialization process on stopper surface.Meanwhile, the release length making stopper during implant surgery is longer, easy impair cardiac tissue.
It is preferred that the external diameter of described connector is 2.5-3.2mm.So make there is enough intensity at the interior wire side closing in of the second plate-like net.If additionally, connector outside dimension is too small, it is easily caused the degraded silk being connected with connector during connecting member forming and occurs fracture or bonding strength to decline.Whereas if connector outside dimension is excessive, the size range of the delivery sheath that stopper is suitable for can be reduced, and be unfavorable for stopper propelling movement in delivery sheath.
Cave at described connector it is preferred that the Intranet of described second plate-like net faces.The wire side of depression is so that stopper can stably and firmly be plugged at ventricular septal heart defect when using.
It is preferred that the external diameter of described first plate-like net is bigger or isometrical than the external diameter of described second plate-like net.First plate-like net is positioned at left ventricle; second plate-like net is positioned at right ventricle; for the patient of ventricular septal defect; blood would generally be flow to right ventricle by left ventricle through ventricular septal defect; this structure makes the first plate-like net being positioned at left ventricle have bigger support force; the impact of blood flow, beneficially stopper can be resisted firmly be clamped at ventricular septal defect, so can effectively block at ventricular septal heart defect.Meanwhile, can avoid surrounding tissue is impeded, reduce the infringement to surrounding tissue.
It is preferred that a length of 3.5-5.5mm of described tubular reticulum.This length is corresponding with the thickness of membranous part of interventricular septum defective tissue, in order to makes stopper preferably be fixed at defect not damaging tissue, and realizes effectively closure.
It is preferred that a length of 6.0-9.5mm of described tubular reticulum.This length is corresponding with the thickness of muscular part of interventricular septum defective tissue, in order to makes stopper preferably be fixed at defect not damaging tissue, and realizes effectively closure.
It is preferred that the material of one first described plate-like net, a tubular reticulum, one second plate-like net and described connector is high molecular degradable silk.Biodegradable polymer material is the copolymer of a kind of or at least two in polylactic acid, polyglycolic acid, polycaprolactone, PPDO, poly butyric ester, condensing model, poly phosphate, polyurethane, Merlon.These materials have good biocompatibility, can fully absorb in human body, it is to avoid implant the foreign body long-term impact on human body.This stopper simply provides a temporary bridge for cardiac repair, is degraded by body, make defect be repaired by autologous tissue completely after completing historic mission, thus avoids metal to retain the internal long term complication brought and potential safety hazard.
A kind of webmaster weaving method, including in the pinhole that pin inserts mould rod, penetrates sewing needle pin hole, knotting compact siro spinning technology by degradable silk.Starting point degradable silk is closely tied a knot, and during braiding, uplink aligns with centre mark point with the intersection point of downlink, with the trend of specification silk.Woven webmaster carries out thermal finalization together with mould rod.After stereotyped, pull out pin, take off webmaster.This weaving method makes the grid of webmaster more uniform, it is easy to operation, decreases cost of manufacture.
A kind of manufacture method of connector, making step includes:
Step 1, webmaster is closed up;
Step 2, webmaster is put into mould;
Step 3, finishing dictyosome;
Step 4, heating degradable silk;
Step 5, molding connector profile and internal whorl;
Step 6, removal dictyosome;
It is preferred that in step 1, first regulate the closing in end margin length of webmaster, make justified margin, close up with degradable silk.
It is preferred that in step 2, the webmaster that will have closed up, through the sleeve pipe in mould.
It is preferred that in step 3, original assembling length is stayed a part for making connector, removes the additional length of webmaster.
It is preferred that in step 4, open attemperating unit, adjust temperature, facing to the degradable silk continuous heating at connector above mould, wherein, adjusting temperature is on high molecular polymer fusing point 40 DEG C-100 DEG C, 5-15 second continuous heating time, in heating process, over-heating can cause other parts hot melt together of dictyosome, thus causes dictyosome destructurized, and greatly reduce the material molecule amount of connector part, material premature breakdown can be caused.Otherwise, heat insufficient, the degradable silk at connector can be caused to be integrated by fully hot melt, it is impossible to form complete connector female thread structure, cause connector inadequate with the bonding strength of induction system.Accordingly, it would be desirable to suitably acid extraction just can complete hot melt.
It is preferred that in step 5, after continuous heating, the degradable silk of connector part is fused together, and removes attemperating unit, the slide block being then shut off in mould, and the thread head of mould is inserted in the slot above mould, keep a period of time.
It is preferred that in step 6, after cooling, the thread head of mould is rotated removal mould, and slide block is slowly removed, dictyosome is removed mould.
The manufacture method of this connector is easily operated, the connector of dimensionally stable can be obtained, and decrease the kind using material on stopper, the degradable silk making composition plate-like net can be securely attached to together, and make connector together with the degradable silk forming plate-like net can be securely attached to, it is not easy to come off.
A kind of dictyosome method for shaping, is packed into dictyosome shaper including the dictyosome with connector, and fixes with fixture, it is carried out together thermal finalization, stereotyped after, dictyosome is removed from the molds.With suture, degradable membrane is packed into dictyosome, and to carry out closing up at closing in end be a solid union joint.This dictyosome method for shaping is easily operated, and the occluder size of making is stable, this kind of method the stopper made has bigger support force and preferable recovery of shape, meets the requirement of operation technique, makes operation more effective, safer.
Positive progressive effect of the present utility model is:
This utility model stopper is knitted to form by high molecular degradable silk, its biodegradation period be 6 months to 2 years, can fully absorb in human body, it is to avoid implant the foreign body long-term impact on human body.Degradable that this utility model is used or the absorbable material of human body, harmless to human non-toxic, there is good biocompatibility.The choked flow film of stopper is biological degradable membrane, its biodegradation period be 6 months to 2 years, complete in human body its treatment mission after degradation in vivo disappear, noresidue foreign body.Dictyosome in the interior wire side center of the second plate-like net is connector through high-temperature hot fusion welding, specifically, dictyosome at high temperature hot melt by the interior wire side center to the second plate-like net, and with mould, heat-fused portion dictyosome is shaped into connector, the degradable silk so making composition plate-like net is not easy to scatter, and can be securely attached together;Simultaneously so that connector can be securely attached together with the degradable silk of composition plate-like net, it is not easy to comes off.It is not installed with the structure that the wire side of connector uses union joint to close up, support force and the recovery of stopper can be increased.Additionally, the advantage that this stopper also has low cost of manufacture.
Accompanying drawing explanation
Fig. 1 is the stopper perspective view of this utility model preferred embodiment.
Fig. 2 is the stopper connector schematic diagram of this utility model preferred embodiment.
Fig. 3 is the A direction view in Fig. 1.
Fig. 4 is the stopper union joint schematic diagram of this utility model preferred embodiment.
Fig. 5 is the mould bar structure schematic diagram of this utility model preferred embodiment.
Fig. 6 is the braiding threading schematic diagram of the webmaster of this utility model preferred embodiment.
Fig. 7 is that the closing in end of the webmaster of this utility model preferred embodiment launches schematic diagram.
Detailed description of the invention
Name preferred embodiment, and combine accompanying drawing and become apparent from intactly illustrating this utility model.
As shown in Figure 1, Figure 2, Figure 3, Figure 4, a kind of degradable cardiac ventricular septal defect closer, it includes the first plate-like net 10, tubular reticulum 30 and the second plate-like net 20 being sequentially connected with, first plate-like net 10 and the second plate-like net 20 are double-deck guard, the two ends of tubular reticulum 30 are connected to interior wire side 11 and the outer wire side 22 of the second plate-like net 20 of the first plate-like net 10, and the first plate-like net 10, tubular reticulum 30 and the second plate-like net 20 are formed in one;Interior wire side 21 center of the second plate-like net 20 is provided with the connector 40 closed up by wire side, and the interior wire side 21 of the second plate-like net 20 is connected for sweat soldering between connector 40;Connector 40 is shaped by the dictyosome hot melt of interior wire side 21 center of the second plate-like net 20 and forms, and connector 40 is provided with female thread in the end relative with the wire side connected;Outer wire side 12 center of the first plate-like net 10 is provided with the union joint 13 for being closed up by wire side, and union joint 13 is shaped by the dictyosome hot melt of outer wire side 12 center of the first plate-like net 10 and forms;The material of the first plate-like net 10, tubular reticulum the 30, second plate-like net 20 and connector 40 is degradation material.
The stopper of the present utility model dictyosome in the interior wire side center of the second plate-like net 20 is connector through high-temperature hot fusion welding, specifically, dictyosome at high temperature hot melt by the interior wire side center to the second plate-like net 20, and with mould, heat-fused portion dictyosome is shaped into connector 40, the degradable silk so making composition plate-like net is not easy to scatter, and can be securely attached together;Simultaneously so that connector 40 can be securely attached together with the degradable silk of composition plate-like net, it is not easy to comes off.
Connector 40 is tubulose, and height is 1.5-2.0mm, and external diameter is 2.5-3.2mm.The interior wire side 21 of the second plate-like net 20 caves at connector 40.The external diameter of the first plate-like net 10 is bigger or isometrical than the external diameter of the second plate-like net 20;The a length of 3.5-9.5mm of tubular reticulum 30.During a length of 3.5-5.5mm, corresponding with the thickness of membranous part of interventricular septum defective tissue;During a length of 6.0-9.5mm, corresponding with the thickness of muscular part of interventricular septum defective tissue.Connector 40 is tubulose, and connector 40 is provided with female thread in the end relative with the wire side 21 connected.
The material of the first plate-like net 10, tubular reticulum 30 and the second plate-like net 20 and connector 40 is high molecular degradable silk.Biodegradable polymer material is the copolymer of a kind of or at least two in polylactic acid, polyglycolic acid, polycaprolactone, PPDO, poly butyric ester, condensing model, poly phosphate, polyurethane, Merlon.In stopper can filling polylactic acid film thus play stop blood flow effect.
This utility model connector is to be formed by degradable silk hot melt, and needs to meet use condition, and not only structure can not excessive cause hindering stopper propelling movement in delivery sheath, also to avoid because the connector that bonding strength causes not pulls.
Table 1, connector size, anti-pulling-out force and propelling movement test table in delivery sheath
Highly mm | External diameter mm | Anti-pulling-out force N | Whether obstruction pushes | |
1 | 2.0 | 1.8 | 6 (weak) | Do not hinder |
2 | 2.0 | 2.0 | 11 (weak) | Do not hinder |
3 | 2.0 | 2.5 | 25 (by force) | Do not hinder |
4 | 1.5 | 2.5 | 20 (by force) | Do not hinder |
5 | 1.8 | 2.8 | 31 (by force) | Do not hinder |
6 | 1.5 | 3.0 | 34 (by force) | Do not hinder |
7 | 2.0 | 3.2 | 41 (by force) | Do not hinder |
8 | 2.0 | 3.5 | 52 (by force) | Hinder |
Test finds, ensures that in use, connector will not be pulled when anti-pulling-out force reaches 15N.By in upper table 1 it can be seen that the size of connector directly influence stopper whether can normally apply to operation among.Inappropriate size design of connector can cause connector to be pulled, or cannot be introduced into pushing in delivery sheath, and these all can cause product to use.
This stopper the first mesh-covered tray is netted of continuous print, uses union joint to close up between its netting twine, and this structure is conducive to the reply of stopper shapes and support force to improve.The stopper of the present utility model dictyosome in the interior wire side center of the second plate-like net is connector through high-temperature hot fusion welding, specifically, dictyosome at high temperature hot melt by the interior wire side center to the second plate-like net, and with mould, heat-fused portion dictyosome is shaped into connector, the degradable silk so making composition plate-like net is not easy to scatter, and can be securely attached together;Simultaneously so that connector can be securely attached together with the degradable silk of composition plate-like net, it is not easy to comes off.
The making of this utility model stopper mainly sews several steps through webmaster molding, connector making, dictyosome sizing and polylactic acid membrane.
During webmaster braiding, pin is inserted as in the pinhole 51 of the mould rod 5 of Fig. 5, degradable silk is penetrated sewing needle pin hole, knotting compact siro spinning technology.Braiding threading rule as shown in Figure 6, including connector manufacturing terminal D, closing in end B (becoming union joint 13 after molding) and starting point C.Closely tiing a knot with degradable silk at starting point C, during braiding, uplink aligns with centre mark point with the intersection point of downlink, with the trend of specification silk.Woven webmaster carries out thermal finalization together with mould rod.After stereotyped, pull out pin, take off webmaster.
Connector making step includes:
1, webmaster is closed up;
2, webmaster is put into mould;
3, finishing dictyosome;
4, heating degradable silk;
5, molding connector profile and internal whorl;
6, removal dictyosome;
Wherein, in step 1, first regulate the closing in end margin length of webmaster, making justified margin, close up with degradable silk, concrete closing in mode is as shown in Figure 7, including going out pin mark 61 and entry point 62, the order of threading according in Fig. 7 go out pin mark 61 and entry point 62 closes up.In step 2, the webmaster that will have closed up, through the sleeve pipe in mould.In step 3, original assembling length is stayed a part for making connector, remove the additional length of webmaster.In step 4, open attemperating unit, adjust temperature, facing to the degradable silk continuous heating at connector above mould.In step 5, after continuous heating, the degradable silk of connector part is fused together, and removes attemperating unit, the slide block being then shut off in mould, and is inserted by the thread head of mould in the slot above mould, keeps a period of time.In step 6, after cooling, the thread head of mould is rotated removal mould, and slide block is slowly removed, dictyosome is removed mould.
Additionally, in step 4, adjusting temperature is on high molecular polymer fusing point 40 DEG C-100 DEG C, 5-15 second continuous heating time.Shown in table 2-table 4 specific as follows, in heating process, over-heating can cause other parts hot melt together of dictyosome, thus causes dictyosome destructurized, and greatly reduces the material molecule amount of connector part, thus can cause material premature breakdown.Otherwise, heat insufficient, the degradable silk at connector can be caused to be integrated by fully hot melt, it is impossible to form complete connector female thread structure, cause connector inadequate with the bonding strength of induction system.Accordingly, it would be desirable to suitably acid extraction just can complete hot melt.
Table 2, L-lactide/glycolides (82/18) degradation material hot melt test table
Heat time heating time s | Heating-up temperature DEG C | Connector hot melt situation | Other part holt melt situations | |
1 | 2 | 240 | Inabundant hot melt | Non-hot melt |
2 | 15 | 170 | Inabundant hot melt | Non-hot melt |
3 | 5 | 240 | Fully hot melt | Non-hot melt |
4 | 5 | 180 | Fully hot melt | Non-hot melt |
5 | 15 | 240 | Fully hot melt | Non-hot melt |
6 | 15 | 180 | Fully hot melt | Non-hot melt |
7 | 5 | 250 | Fully hot melt | Part holt melt |
8 | 20 | 180 | Fully hot melt | Part holt melt |
Table 3, PPDO degradation material hot melt test table
Heat time heating time s | Heating-up temperature DEG C | Connector hot melt situation | Other part holt melt situations | |
1 | 2 | 200 | Inabundant hot melt | Non-hot melt |
2 | 15 | 130 | Inabundant hot melt | Non-hot melt |
3 | 5 | 200 | Fully hot melt | Non-hot melt |
4 | 5 | 140 | Fully hot melt | Non-hot melt |
5 | 15 | 200 | Fully hot melt | Non-hot melt |
6 | 15 | 140 | Fully hot melt | Non-hot melt |
7 | 5 | 210 | Fully hot melt | Part holt melt |
8 | 20 | 140 | Fully hot melt | Part holt melt |
Table 4, L-lactide/caprolactone (70/30) degradation material hot melt test table
Heat time heating time s | Heating-up temperature DEG C | Connector hot melt situation | Other part holt melt situations | |
1 | 2 | 210 | Inabundant hot melt | Non-hot melt |
2 | 15 | 140 | Inabundant hot melt | Non-hot melt |
3 | 5 | 210 | Fully hot melt | Non-hot melt |
4 | 5 | 150 | Fully hot melt | Non-hot melt |
5 | 15 | 210 | Fully hot melt | Non-hot melt |
6 | 15 | 150 | Fully hot melt | Non-hot melt |
7 | 5 | 220 | Fully hot melt | Part holt melt |
8 | 20 | 150 | Fully hot melt | Part holt melt |
Dictyosome sizing includes dictyosome upper mold and dictyosome heat treatment shaping.During dictyosome upper mold, the aforementioned dictyosome with connector is packed into dictyosome shaper, and fixes with fixture, it is carried out together thermal finalization, stereotyped after, dictyosome is removed from the molds.With suture, polylactic acid membrane is packed into dictyosome, and to carry out closing at closing in end be a union joint.
In description of the present utility model, it will be appreciated that, term " on ", D score, "front", "rear", "left", "right", " vertically ", " level ", " top ", " end ", " interior ", the orientation of the instruction such as " outward " or position relationship be based on orientation shown in the drawings or position relationship, it is for only for ease of description this utility model and simplifies description, rather than instruction or the device of hint indication or element must have specific orientation, with specific azimuth configuration and operation, therefore it is not intended that to restriction of the present utility model.
Although the foregoing describing detailed description of the invention of the present utility model, it will be appreciated by those of skill in the art that this is merely illustrative of, protection domain of the present utility model is defined by the appended claims.These embodiments, on the premise of without departing substantially from principle of the present utility model and essence, can be made various changes or modifications, but these changes and amendment each fall within protection domain of the present utility model by those skilled in the art.
Claims (8)
1. a degradable cardiac ventricular septal defect closer, it is characterized in that, it includes one first plate-like net, a tubular reticulum and the one second plate-like net being sequentially connected with, described first plate-like net and described second plate-like net are double-deck guard, the two ends of described tubular reticulum are connected to interior wire side and the outer wire side of described second plate-like net of described first plate-like net, and described first plate-like net, described tubular reticulum and described second plate-like net are formed in one;The interior wire side center of described second plate-like net is provided with the connector for being closed up by wire side, and described connector is shaped by the dictyosome hot melt of the interior wire side center of described second plate-like net and forms;Described connector is provided with female thread in the end relative with the wire side connected;The outer wire side center of described first plate-like net is provided with the union joint for being closed up by wire side, and described union joint is shaped by the dictyosome hot melt of the outer wire side center of described first plate-like net and forms;The material of described first plate-like net, tubular reticulum, the second plate-like net and connector is degradation material, and the height of described tubular reticulum is 3.5-9.5mm.
Degradable cardiac ventricular septal defect closer the most as claimed in claim 1, it is characterised in that described connector is tubulose, the height of described connector is 1.5-2.0mm.
Degradable cardiac ventricular septal defect closer the most as claimed in claim 2, it is characterised in that the external diameter of described connector is 2.5-3.2mm.
Degradable cardiac ventricular septal defect closer the most as claimed in claim 1, it is characterised in that the Intranet of described second plate-like net faces and caves at described connector.
Degradable cardiac ventricular septal defect closer the most as claimed in claim 1, it is characterised in that the external diameter of described first plate-like net is bigger or isometrical than the external diameter of described second plate-like net.
Degradable cardiac ventricular septal defect closer the most as claimed in claim 1, it is characterised in that a length of 3.5-5.5mm of described tubular reticulum.
Degradable cardiac ventricular septal defect closer the most as claimed in claim 1, it is characterised in that a length of 6.0-9.5mm of described tubular reticulum.
Degradable cardiac ventricular septal defect closer the most as claimed in claim 1, it is characterised in that the material of described first plate-like net, described tubular reticulum, described second plate-like net and described connector is high molecular degradable silk.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017113531A1 (en) * | 2015-12-31 | 2017-07-06 | 常州锦葵医疗器械有限公司 | Degradable occluder |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2017113531A1 (en) * | 2015-12-31 | 2017-07-06 | 常州锦葵医疗器械有限公司 | Degradable occluder |
US11337683B2 (en) | 2015-12-31 | 2022-05-24 | Mallow Medical (Shanghai) Co., Ltd. | Degradable occluder |
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Address after: 15th Building, 388 Yindu Road, Xuhui District, Shanghai, 200231 Patentee after: Shanghai Jinkui Medical Devices Co., Ltd. Address before: Room 102, D Workshop, 1618 Yishan Road, Minhang District, Shanghai, 201103 Patentee before: Shanghai Jinkui Medical Implements Co., Ltd. |