CN207785224U - Degradable heart occluder for left auricle - Google Patents
Degradable heart occluder for left auricle Download PDFInfo
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- CN207785224U CN207785224U CN201521137627.8U CN201521137627U CN207785224U CN 207785224 U CN207785224 U CN 207785224U CN 201521137627 U CN201521137627 U CN 201521137627U CN 207785224 U CN207785224 U CN 207785224U
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Abstract
The utility model discloses a kind of degradable heart occluder for left auricle, including sequentially connected first plate-like net, tubular reticulum and the second plate-like net, first plate-like net is additionally provided with closing in line, closing in line is arranged in all cyclic annular cables, and the first plate-like net forms continuous netted face after the closing in of closing in line；Second plate-like net is equipped with connector for wire side to close up, and connector is shaped by the dictyosome hot melt at the interior wire side center of the second plate-like net, the first plate-like net, tubular reticulum, the second plate-like net and connector material be degradation material.The structure that the utility model plugging device closing in line closes up increases the support force and recovery of plugging device, and reduces manufacture difficulty, reduces manufacturing cost.The utility model not only enables the degradable silk of the discoid net of group be securely attached together, and connector is enable to be securely attached together with the degradable silk for organizing discoid net, it is not easy to fall off.
Description
Technical field
The utility model is related to a kind of degradable heart occluder for left auricle.
Background technology
Left auricle of heart is the ear folliculus stretched out from atrium sinistrum, belongs to a part for atrium sinistrum, it is that atrium sinistrum mainly forms
Position.Left auricle of heart is the long tubular structure of a buckle, and auricle wall forms girder by musculi pectinati, had the gap between girder.Left auricle of heart
The neck for having a 10~40mm of diameter between left room chamber, between left superior pulmonary vein and annulus of mitral valve, circumflex branch of coronary artery
Close to left auricle of heart open base portion.The unique hook formation of left auricle of heart and the abundant trabecular muscles of lining endothelium easily cause blood flow silt
It is stagnant；The increase of patients with atrial fibrillation heart cavity diameter and left auricle of heart internal membrane of heart fibrosis etc. are all the risk factors of thrombosis.Non-valvular disease
90% or more patients with atrial fibrillation left atrial thrombus is present in left auricle of heart, and thrombosis makes incidence of stroke increase by 3 times in left auricle of heart.I.e.
Make recovery Dou Lvhou, left auricle of heart shrinks a suppression, it is possible to re-forming thrombus.If the root portion that fibrillation patient thrombus occurs
Position left auricle of heart is blocked, and the risk of fibrillation patient apoplexy can be greatly reduced.Left atrial appendage occlusion art is current universal precaution atrial fibrillation
The treatment new trend of patient's palsy, it can effectively reduce the case fatality rate of patient, disability rate, while reduce the generation of bleeding.
Heart left auricle of heart is common congenital heart disease, and traditional therapeutic modality is surgical operation.Surgical operation is controlled
Treatment method, patient need to surgically open chest, and maximum disadvantage is：(1) need extracorporal circulatory system, operation that may cause in art
Complication and lead to death；(2) surgery operating wound is big, and postoperative there are scars；(3) surgery cost is expensive.
From the 1980s with intubation intervention diagnosis and the development and raising for the treatment of technology, China is gradually introducing minimally invasive
Interventional technique treats congenital heart disease, is rapidly developed by the method for Minimally Interventional Therapy left auricle of heart, highly developed.Phase
Than traditional surgery, Minimally Interventional Therapy is a kind of modern high technology minimal invasive treatment, by femoral venous puncture, in medicine shadow
As equipment guiding under, by guide wire along femoral vein, inferior caval vein until enter atrium dextrum, shape atrial septal puncture, into a left side
Atrium reaches left auricle of heart.Delivery conduit is then placed in left auricle of heart position along guide wire, finally by occluder for left auricle in defeated
It send and pushes to implementation Occlusion therapy at left auricle of heart in conduit.Such Minimally Interventional Therapy have do not operate on, wound is small, complication
Less, restore fast, effect is good, indication range is wide and the relatively low advantage of surgery cost.
Though having by the therapy of minimally invasive intervention operation implantation occluder for left auricle many of the above relative to conventional surgical
The advantage of operation.But since the material used in the main body rack of the occluder for left auricle of present Clinical practice is mainly NiTi
B alloy wire, since this metalloid material cannot degrade, be chronically implanted can and tissue be inflamed, the reactions such as blood coagulation, even
It is a degree of damage, therefore there are certain defects, it is possible to there are risks used below：(1) Nitinol is
Nondegradable metal alloy compositions, although its biocompatibility is proved, the long term risk of long-term Permanent implantation is still
It can not be perfectly controlled；(2) due to Nitinol Permanent implantation and non-degradable, safety of the heart to human body is permanently retained
Property, influence of the fixed-size heart occluder to the heart of the continuous growth and development of children still lack long-term Follow-up Data,
It may influence the growing of the patient's heart of undeveloped mature；(3) complication such as nickel precipitation, nickel allergy do not have explicitly yet
Scientific appraisal.
On heart occluder surface by complete endothelialization, after heart defect is repaired by body autologous tissue, heart blocks
Necessity that device is not retained in vivo completely.Therefore, ideal heart occluder should provide one for heart itself reparation
Temporary bridge is degraded by body after completing historic mission, defect is made to be repaired completely by autologous tissue, to avoid metal from retaining body
The long term complication and security risk inside brought.
The support construction for the degradable plugging device introduced in United States Patent (USP) US08480709B2 is cut by pipe, is blocked
The tie point of two disks of device is similar with dual welding spots, makes protrusion at two disk centers, can increase plugging device surface local thrombus
The risk of formation is unfavorable for the endothelialization process on plugging device surface, meanwhile, the release of plugging device is made during implant surgery
Length is longer, is easy to damage heart tissue, and the plugging device compliance and recovery that are fabricated to by this method are poor, needs
It is assisted to reply original shape by locking device.
Utility model content
The technical problems to be solved in the utility model is deposited to solve the heart occluder for left auricle of existing Clinical practice
The long term risk the problem of, and overcome the prior art there are the poor defect of the compliance of degradable plugging device and recovery,
A kind of degradable heart occluder for left auricle is provided.
The utility model is to solve above-mentioned technical problem by following technical proposals：
A kind of degradable heart occluder for left auricle, feature are comprising sequentially connected 1 first plate-like net,
One tubular reticulum and one second plate-like net, the first plate-like net are single layer guard, and the second plate-like net is the double-deck guard, described
The both ends of tubular reticulum are connected to the outer wire side of the first plate-like net and the second plate-like net, the first plate-like net,
The tubular reticulum and the second plate-like net are integrally formed；It is equipped with and is used for net at the interior wire side center of the second plate-like net
The connector that face is closed up, the connector are shaped by the dictyosome hot melt at the interior wire side center of the second plate-like net, institute
The material for stating the first plate-like net, tubular reticulum, the second plate-like net and connector is degradation material.
Preferably, the first plate-like net includes a closing in end, the closing in end is the cyclic annular cable of multiple adjoinings successively,
The first plate-like net is additionally provided with a closing in line, and the closing in line is arranged in all cyclic annular cables, through the closing in line
The first plate-like net forms the netted face of continuous formation after closing in.In this way so that outer net face is more smooth, can increase plugging device
Support force and recovery, it is possible to reduce the risk that plugging device surface local thrombus is formed is conducive to accelerate plugging device surface
Endothelialization process makes at heart left auricle of heart being repaired by autologous tissue earlier.Meanwhile reducing releasing for plugging device in surgical procedure
The damage to heart can be greatly reduced in degree of lengthening, and keep operation more effective, safer.
Preferably, the connector is tubulose, the height of the connector is 1.5-2.0mm.In this way so that the second plate-like
There is enough intensity at the interior wire side closing in of net.If the height of connector is too small, the thread turns inside connector is very few, meeting
Cause to connect with transport system insecure and there are the risks that plugging device falls off., whereas if the height of connector is excessive, can increase
The risk for adding plugging device surface local thrombus to be formed can cause the side plugging device superficial cell climbing with connector slower,
Extend the endothelialization process on plugging device surface.Meanwhile making the release length of plugging device longer during implant surgery, it is easy
Impair cardiac tissue.
Preferably, the outer diameter of the connector is 2.5-3.2mm.In this way so that having at the interior wire side closing in of the second plate-like net
Enough intensity.In addition, if connector outer diameter is too small, it is easy to cause and is connect with connector during connecting member forming
Degradation silk occur fracture or bonding strength decline., whereas if connector outer diameter is excessive, plugging device can be reduced and be applicable in
The size range of delivery sheath, and it is unfavorable for push of the plugging device in delivery sheath.
It is recessed at the connector preferably, the Intranet of the second plate-like net faces.The wire side of recess can to seal
Stifled device using when can stably and firmly be plugged at heart left auricle of heart patent.
Preferably, the outer diameter of the second plate-like net is bigger than the outer diameter of the first plate-like net.Make to be located at atrium sinistrum in this way
The second plate-like net there is larger support force, the impact of blood flow can be resisted, can effectively will be at heart left auricle of heart patent
It blocks.
Preferably, the one first plate-like net, a tubular reticulum, one second plate-like net and the connector material be
High molecular degradable silk.Biodegradable polymer material be polylactic acid, polyglycolic acid, polycaprolactone, polydioxanone,
One kind in poly butyric ester, polyanhydride, polyphosphate, polyurethane, makrolon or at least two copolymer.These materials
Material has good biocompatibility, can be fully absorbed in human body, avoids long-term influence of the implantation foreign matter on human body.This
Kind of plugging device only provides a temporary bridge for cardiac repair, is degraded by body after completion historic mission, make defect completely by
Autologous tissue repairs, the long term complication to avoid metal retention from bringing in vivo and security risk.
Preferably, the connector is tubulose, the connector is equipped with internal thread in the end opposite with the dictyosome.It is logical
The connector for crossing this helicitic texture, it is more secured with the connection of transport system, can plugging device easily be passed through into transport system
It is transported at heart left auricle of heart.
A kind of webmaster weaving method includes being inserted into pin in the pinhole of mould stick, degradable silk is penetrated sewing needle needle
Hole knots and closely connects.Starting point is closely knotted with degradable silk, and the intersection point of uplink and downlink is marked with center when braiding
Point alignment is remembered, with the trend of specification silk.Woven webmaster carries out thermal finalization together with mould stick.After stereotyped, pin is pulled out,
Remove webmaster.This weaving method keeps the grid of webmaster more uniform, easily operated, reduces the production cost.
A kind of production method of connector, making step include：
Step 1 closes up to webmaster；
Webmaster is put into mold by step 2；
Step 3, finishing dictyosome；
Step 4, the degradable silk of heating；
Step 5, molding connector shape and internal whorl；
Step 6 removes dictyosome；
Preferably, in step 1, the closing in end margin length of webmaster is first adjusted, edge is made to be aligned, closed up with degradable silk.
Preferably, in step 2, the webmaster that will have been closed up passes through the casing in mold.
Preferably, in step 3, stays a part to be used for making connector in original assembly length, remove the extra of webmaster
Length.
Preferably, in step 4, temperature control device is opened, adjusts temperature, against the degradable silk at connector above mold
Continuous heating, wherein adjustment temperature is 5-15 seconds continuous heating time, to add 40 DEG C -100 DEG C on high molecular polymer fusing point
In thermal process, over-heating can cause the other parts of dictyosome to heat together, destructurized so as to cause dictyosome, and greatly
The material molecule amount for reducing connector part, can cause material premature breakdown.Conversely, heating is insufficient, can cause at connector
Degradable silk can not fully heat and be integrated, complete connector internal thread structure can not be formed, cause connector with it is defeated
Send the bonding strength of system inadequate.Therefore, it is necessary to suitable acid extractions could complete to heat.
Preferably, in step 5, after continuous heating, the degradable silk of connector part is fused together, and removes temperature control dress
It sets, the sliding block being then shut off in mold, and the thread head of mold is inserted into the slot above mold, kept for a period of time.
Preferably, in step 6, after cooling, the thread head rotation of mold is removed into mold, and sliding block is slowly removed,
Dictyosome is removed into mold.
The production method of this connector is easily operated, can obtain the connector of dimensionally stable, and reduces plugging device
On using material type, so that a degradable silk for the discoid net of group is securely attached to together, and make connector and composition
The degradable silk of plate-like net can be securely attached to together, it is not easy to be fallen off.
A kind of dictyosome method for shaping includes that the dictyosome with connector is packed into dictyosome shaper, is used in combination fixture solid
It is fixed, it is carried out thermal finalization together, after stereotyped, dictyosome is removed from the molds.Degradable membrane is packed into dictyosome with suture,
And it is a smooth disk at closing in end close up.This dictyosome method for shaping is easily operated, and the occluder size of making is stablized,
There is larger support force and preferable recovery of shape by the plugging device that this kind of method makes, meet the requirement of surgical procedure,
Keep operation more effective, safer.
The positive effect of the utility model is：
The utility model plugging device is knitted to form by high molecular degradable silk, and biodegradation period is 6 months to 2 years,
It can be fully absorbed in human body, avoid long-term influence of the implantation foreign matter on human body.It is degradable used in the utility model
Or the absorbable material of human body, it is non-toxic to humans, there is good biocompatibility.The choked flow film of plugging device is biology
Degradable membrane, biodegradation period are 6 months to 2 years, and degradation in vivo after it treats mission is completed in human body and is disappeared, nothing
Retained foreign body.It is connector that dictyosome at the interior wire side center of the second plate-like net, which passes through high temperature sweat soldering, specifically, logical
The dictyosome crossed at the interior wire side center to the second plate-like net heats at high temperature, is used in combination mold that heat-fused portion dictyosome is shaped into company
Fitting makes the degradable silk of the discoid net of group be not easy to scatter, can be securely attached together in this way；Simultaneously so that connector
It can be securely attached together with the degradable silk for organizing discoid net, it is not easy to fall off.The wire side for being not installed with connector uses
The structure that closing in line closes up so that the wire side is more smooth, can increase the support force and recovery of plugging device, it is possible to reduce block
The risk that device surface local thrombus is formed is conducive to the endothelialization process for accelerating plugging device surface, makes at heart left auricle of heart earlier
Repaired by autologous tissue.Meanwhile reducing the release length of plugging device in surgical procedure, the damage to heart can be greatly reduced
Wound, keeps operation more effective, safer；In addition, this plugging device also has the advantages that manufacturing cost is low.
Description of the drawings
Fig. 1 is the plugging device dimensional structure diagram of the utility model preferred embodiment.
Fig. 2 is the plugging device connector schematic diagram of the utility model preferred embodiment.
Fig. 3 is the A direction views in Fig. 1.
Fig. 4 is partial enlargement signal at the closing in end of the outer wire side of the first plate-like net of the utility model preferred embodiment
Figure.
Fig. 5 is the mould stick structural schematic diagram of the utility model preferred embodiment.
Fig. 6 is that the braiding of the webmaster of the utility model preferred embodiment threads schematic diagram.
Fig. 7 is the closing in end expanded schematic diagram of the webmaster of the utility model preferred embodiment.
Specific implementation mode
A preferred embodiment is named, and completely illustrates the utility model in conjunction with attached drawing to become apparent from.
As shown in Figure 1, Figure 2, Figure 3, Figure 4, a kind of degradable heart occluder for left auricle comprising sequentially connected
One plate-like net 10, tubular reticulum 30 and the second plate-like net 20, the first plate-like net 10 are single layer guard, and the second plate-like net 20 is Double-level Reticulated
Cover, the both ends of tubular reticulum 30 are connected to the outer wire side 22 of the first plate-like net 10 and the second plate-like net 20, the first plate-like net 10,
Tubular reticulum 30 and the second plate-like net 20 are integrally formed；It is equipped at 21 center of interior wire side of second plate-like net 20 and wire side closes up
Connector 40 connects between the interior wire side 21 and connector 40 of second plate-like net 20 for sweat soldering；First plate-like net 10 includes
Closing in end 13, closing in end 13 are the cyclic annular cable 14 of multiple adjoinings successively, and the first plate-like net 10 is additionally provided with closing in line 15, closing in line
15 are arranged in all cyclic annular cables 14, and first plate-like net 10 forms continuous netted face after the closing in of closing in line 15.First disk
Shape net 10, tubular reticulum 30, the second plate-like net 20 and connector 40 material be degradation material.
Dictyosome of the plugging device of the utility model at the interior wire side center of the second plate-like net 20 passes through high temperature sweat soldering
Mold is used in combination specifically, being heated at high temperature by the dictyosome at the interior wire side center to the second plate-like net 20 for connector
Heat-fused portion dictyosome is shaped into connector 40, makes the degradable silk of the discoid net of group be not easy to scatter in this way, can connect securely
It is connected together；Simultaneously so that connector 40 can be securely attached together with the degradable silk for organizing discoid net, it is not easy to de-
It falls.
Connector 40 is tubulose, is highly 1.5-2.0mm, outer diameter 2.5-3.2mm.The interior wire side 21 of second plate-like net 20
It is recessed at towards connector 40.The outer diameter of second plate-like net 20 is bigger than the outer diameter of the first plate-like net 10.Connector 40 is tubulose, connection
Part 40 is equipped with internal thread in the end opposite with the wire side 21 to connect.
First plate-like net 10, tubular reticulum 30 and the material of the second plate-like net 20 and connector 40 are high molecular degradable
Silk.Biodegradable polymer material is polylactic acid, polyglycolic acid, polycaprolactone, polydioxanone, polyhydroxybutyrate
One kind in ester, polyanhydride, polyphosphate, polyurethane, makrolon or at least two copolymer.It can be filled in plugging device poly-
Lactic acid film is to play the role of stopping blood flow.
The utility model connector is to be heated by degradable silk, and need to meet use condition, not only structure
It excessive cannot cause to hinder push of the plugging device in delivery sheath, also to avoid because of not caused enough the connector of bonding strength
It pulls.
Table 1, connector size, anti-pulling-out force and the push test table in delivery sheath
| Height mm | Outer diameter mm | Anti- pulling-out force N | Whether obstruction pushes | |
| 1 | 2.0 | 1.8 | 6 (weak) | It does not hinder |
| 2 | 2.0 | 2.0 | 11 (weak) | It does not hinder |
| 3 | 2.0 | 2.5 | 25 (strong) | It does not hinder |
| 4 | 1.5 | 2.5 | 20 (strong) | It does not hinder |
| 5 | 1.8 | 2.8 | 31 (strong) | It does not hinder |
| 6 | 1.5 | 3.0 | 34 (strong) | It does not hinder |
| 7 | 2.0 | 3.2 | 41 (strong) | It does not hinder |
| 8 | 2.0 | 3.5 | 52 (strong) | It hinders |
It is found in test, ensures that connector will not be pulled in use when anti-pulling-out force reaches 15N.Pass through upper table
It can be seen that the size of connector directly influences whether plugging device can normally apply among operation in 1.Connector
Inappropriate size design connector can be caused to be pulled, or cannot be introduced into delivery sheath and pushed, these all can
Cause product that can not use.
The first mesh-covered tray of this plugging device is continuous netted face, is closed up using closing in line between cable so that outside first
Dropbox is the wire side of flat smooth, and no protrusion, which is conducive to the reply of stopper shapes and support force improves, and more conducively adds
The endothelialization process on fast plugging device surface, makes heart defect be repaired earlier by autologous tissue.The plugging device of the utility model exists
It is connector that dictyosome at the interior wire side center of second plate-like net, which passes through high temperature sweat soldering, specifically, by the second disk
Dictyosome at the interior wire side center of shape net heats at high temperature, is used in combination mold that heat-fused portion dictyosome is shaped into connector, in this way
Make the degradable silk of the discoid net of group be not easy to scatter, can be securely attached together；Simultaneously so that connector and group are discoid
The degradable silk of net can be securely attached together, it is not easy to be fallen off.
Webmaster molding is mainly passed through in the making of the utility model plugging device, connector makes, dictyosome is shaped and polylactic acid membrane
Sew several steps.
When webmaster weaves, pin is inserted into the pinhole 51 such as the mould stick 5 of Fig. 5, degradable silk is penetrated into sewing needle needle
Hole knots and closely connects.The threading rule of braiding as shown in fig. 6, including connector manufacturing terminal D, closing in end B (after molding at
For closing in end 13) and starting point C.It is closely knotted with degradable silk at starting point C, intersection point and the center of uplink and downlink when braiding
Point alignment is marked, with the trend of specification silk.Woven webmaster carries out thermal finalization together with mould stick.After stereotyped, pin is pulled out
Son removes webmaster.
Connector making step includes：
1, it closes up to webmaster；
2, webmaster is put into mold；
3, dictyosome is modified；
4, degradable silk is heated；
5, connector shape and internal whorl are molded；
6, dictyosome is removed；
Wherein, in step 1, the closing in end margin length of webmaster is first adjusted, edge is made to be aligned, closed up with degradable silk, tool
The closing in mode of body is as shown in fig. 7, including pin mark 61 and entry point 62 is gone out, the sequence of threading goes out pin mark according in Fig. 7
61 and entry point 62 close up.In step 2, the webmaster that will have been closed up passes through the casing in mold.In step 3, in original
Have stays a part to be used for making connector in assembly length, removes the additional length of webmaster.In step 4, temperature control device is opened, is adjusted
Whole temperature, against the degradable silk continuous heating at connector above mold.In step 5, after continuous heating, connector portion
The degradable silk divided is fused together, and removes temperature control device, the sliding block being then shut off in mold, and the thread head of mold is inserted into
In slot above mold, kept for a period of time.In step 6, after cooling, the thread head rotation of mold is removed into mold, and
Sliding block is slowly removed, dictyosome is removed into mold.
In addition, in step 4, adjustment temperature is continuous heating time 5- 40 DEG C -100 DEG C on high molecular polymer fusing point
15 seconds.Shown in table 2- tables 4 specific as follows, in heating process, over-heating can cause the other parts of dictyosome to heat together, to
Cause dictyosome destructurized, and greatly reduce the material molecule amount of connector part, to which material premature breakdown can be caused.
Conversely, heating is insufficient, it can cause the degradable silk at connector that can not fully heat and be integrated, can not be formed complete
Connector internal thread structure causes the bonding strength of connector and transport system inadequate.Therefore, it is necessary to suitable heating temperature and
Time could complete to heat.
Table 2, L- lactide/glycolides (82/18) degradation material hot melt test table
| Heating time s | Heating temperature DEG C | Connector heats situation | Other parts heat situation | |
| 1 | 2 | 240 | It does not heat fully | It does not heat |
| 2 | 15 | 170 | It does not heat fully | It does not heat |
| 3 | 5 | 240 | Fully hot melt | It does not heat |
| 4 | 5 | 180 | Fully hot melt | It does not heat |
| 5 | 15 | 240 | Fully hot melt | It does not heat |
| 6 | 15 | 180 | Fully hot melt | It does not heat |
| 7 | 5 | 250 | Fully hot melt | Part holt melt |
| 8 | 20 | 180 | Fully hot melt | Part holt melt |
Table 3, polydioxanone degradation material hot melt test table
Table 4, L- lactides/caprolactone (70/30) degradation material hot melt test table
| Heating time s | Heating temperature DEG C | Connector heats situation | Other parts heat situation | |
| 1 | 2 | 210 | It does not heat fully | It does not heat |
| 2 | 15 | 140 | It does not heat fully | It does not heat |
| 3 | 5 | 210 | Fully hot melt | It does not heat |
| 4 | 5 | 150 | Fully hot melt | It does not heat |
| 5 | 15 | 210 | Fully hot melt | It does not heat |
| 6 | 15 | 150 | Fully hot melt | It does not heat |
| 7 | 5 | 220 | Fully hot melt | Part holt melt |
| 8 | 20 | 150 | Fully hot melt | Part holt melt |
Dictyosome sizing includes dictyosome upper mold and dictyosome heat treatment shaping.When dictyosome upper mold, the aforementioned net with connector
Body is packed into dictyosome shaper, and fixture is used in combination to fix, it is carried out thermal finalization together, after stereotyped, by dictyosome from mold
It takes out.Polylactic acid membrane is packed into dictyosome with suture, and it is a smooth disk at closing in end close up.
In the description of the present invention, it should be understood that term "upper", "lower", "front", "rear", "left", "right",
The orientation or positional relationship of the instructions such as "vertical", "horizontal", "top", "bottom", "inner", "outside" be orientation based on ... shown in the drawings or
Position relationship is merely for convenience of describing the present invention and simplifying the description, and does not indicate or imply the indicated device or member
Part must have a particular orientation, with specific azimuth configuration and operation, therefore should not be understood as limiting the present invention.
Although the foregoing describe specific embodiment of the present utility model, it will be appreciated by those of skill in the art that
This is merely illustrative of, and the scope of protection of the utility model is defined by the appended claims.Those skilled in the art
Under the premise of without departing substantially from the principles of the present invention and essence, many changes and modifications may be made,
But these change and modification each fall within the scope of protection of the utility model.
Claims (8)
1. a kind of degradable heart occluder for left auricle, which is characterized in that it includes sequentially connected 1 first plate-like net, one
Tubular reticulum and one second plate-like net, the first plate-like net are single layer guard, and the second plate-like net is the double-deck guard, the pipe
The both ends of shape net are connected to the outer wire side of the first plate-like net and the second plate-like net, the first plate-like net, institute
It states tubular reticulum and the second plate-like net is integrally formed；It is equipped with for by wire side at the interior wire side center of the second plate-like net
The connector of closing in, the connector is shaped by the dictyosome hot melt at the interior wire side center of the second plate-like net, described
First plate-like net, tubular reticulum, the second plate-like net and connector material be degradation material.
2. degradable heart occluder for left auricle as described in claim 1, which is characterized in that the first plate-like net includes
One closing in end, the closing in end are the cyclic annular cable of multiple adjoinings successively, and the first plate-like net is additionally provided with a closing in line, described
Closing in line is arranged in all cyclic annular cables, and the first plate-like net forms continuous formation after closing in line closing in
Netted face.
3. degradable heart occluder for left auricle as described in claim 1, which is characterized in that the connector is tubulose,
The height of the connector is 1.5-2.0mm.
4. degradable heart occluder for left auricle as claimed in claim 3, which is characterized in that the outer diameter of the connector is
2.5-3.2mm。
5. degradable heart occluder for left auricle as described in claim 1, which is characterized in that the second plate-like net it is interior
Wire side is recessed towards at the connector.
6. degradable heart occluder for left auricle as described in claim 1, which is characterized in that outside the second plate-like net
Diameter is bigger than the outer diameter of the first plate-like net.
7. degradable heart occluder for left auricle as described in claim 1, which is characterized in that the first plate-like net, institute
The material for stating tubular reticulum, the second plate-like net and the connector is high molecular degradable silk.
8. degradable heart occluder for left auricle as described in claim 1, which is characterized in that the connector is tubulose,
The connector is equipped with internal thread in the end opposite with the wire side to connect.
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521137627.8U CN207785224U (en) | 2015-12-31 | 2015-12-31 | Degradable heart occluder for left auricle |
| EP16880339.3A EP3398533A4 (en) | 2015-12-31 | 2016-04-08 | Degradable occluder |
| SG11201805561SA SG11201805561SA (en) | 2015-12-31 | 2016-04-08 | Degradable occluder |
| US16/066,399 US11337683B2 (en) | 2015-12-31 | 2016-04-08 | Degradable occluder |
| PCT/CN2016/078756 WO2017113531A1 (en) | 2015-12-31 | 2016-04-08 | Degradable occluder |
| JP2018553276A JP6752289B2 (en) | 2015-12-31 | 2016-04-08 | Disassembleable occluder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201521137627.8U CN207785224U (en) | 2015-12-31 | 2015-12-31 | Degradable heart occluder for left auricle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207785224U true CN207785224U (en) | 2018-08-31 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110432935A (en) * | 2019-08-01 | 2019-11-12 | 上海形状记忆合金材料有限公司 | Degradable plugging device and preparation method thereof |
| CN112914660A (en) * | 2021-02-01 | 2021-06-08 | 上海锦葵医疗器械股份有限公司 | Heart left auricle occluder with two smooth end surfaces and manufacturing method thereof |
| CN113558834A (en) * | 2021-08-09 | 2021-10-29 | 广东脉搏医疗科技有限公司 | Connecting assembly for cardiovascular implants |
-
2015
- 2015-12-31 CN CN201521137627.8U patent/CN207785224U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110432935A (en) * | 2019-08-01 | 2019-11-12 | 上海形状记忆合金材料有限公司 | Degradable plugging device and preparation method thereof |
| CN112914660A (en) * | 2021-02-01 | 2021-06-08 | 上海锦葵医疗器械股份有限公司 | Heart left auricle occluder with two smooth end surfaces and manufacturing method thereof |
| CN113558834A (en) * | 2021-08-09 | 2021-10-29 | 广东脉搏医疗科技有限公司 | Connecting assembly for cardiovascular implants |
| CN113558834B (en) * | 2021-08-09 | 2024-04-26 | 广东脉搏医疗科技有限公司 | Connection assembly for cardiovascular implant |
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Address after: 15th Building, 388 Yindu Road, Xuhui District, Shanghai, 200231 Patentee after: Shanghai Jinkui Medical Devices Co., Ltd. Address before: Room 102, D Workshop, 1618 Yishan Road, Minhang District, Shanghai, 201103 Patentee before: Shanghai Jinkui Medical Implements Co., Ltd. |
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