CN207786607U - A kind of evenly mixing device for test sample in analyzer reaction tank - Google Patents

A kind of evenly mixing device for test sample in analyzer reaction tank Download PDF

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Publication number
CN207786607U
CN207786607U CN201721804439.5U CN201721804439U CN207786607U CN 207786607 U CN207786607 U CN 207786607U CN 201721804439 U CN201721804439 U CN 201721804439U CN 207786607 U CN207786607 U CN 207786607U
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China
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reaction tank
valve
sebific duct
sample
waste liquid
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Withdrawn - After Issue
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CN201721804439.5U
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Chinese (zh)
Inventor
许焕樟
刘治志
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Shenzhen Dymind Biotechnology Co Ltd
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Shenzhen Dymind Biotechnology Co Ltd
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Abstract

The utility model discloses a kind of evenly mixing devices for test sample in analyzer reaction tank comprising reaction tank, optical measurement module and the sebific duct for connecting reaction tank and optical measurement module;There are multiple reagent inlets on the reaction tank, underface is designed with waste liquid port, below the reagent inlet, Position Design close to reaction tank intracavity bottom has sample channel, the reagent inlet is for adding in reagent to reaction tank, the waste liquid port connects waste liquid module, and the sample channel and optical measurement module pass through piping connection;It is provided with Valve for compressing tubular liner on the sebific duct of connection sample channel and optical measurement module, the Valve for compressing tubular liner is realized by repeatedly compressing and unclamp the sebific duct and reaction tank repeatedly is sucked out in sample liquid and is pushed into reaction tank.Easy to operate using device provided by the utility model, reaction tank structure design is simple, and mixed effect is good.

Description

A kind of evenly mixing device for test sample in analyzer reaction tank
Technical field
The utility model is related to medical instruments fields, more particularly to one kind is for test sample in analyzer reaction tank Evenly mixing device.
Background technology
The existing medical instrument for being related to fluid path pipe-line system is drawn sample to be tested and is added in internal-response pond (cup) Reaction carries out the instrument of relevant parameter test again after being incubated, as cellanalyzer, Full-automatic chemiluminescence immunoassay analysis meter, Full automatic biochemical apparatus etc. needs to add the samples in reaction tank, in order to fully react, ensures the accurate of instrument test result Property, repeatability, must obtain mixing after sample and the mixing of corresponding reagent, the degree direct influence test result of mixing it is accurate Property, repeatability.The method for being currently used in instrument mixing sample and corresponding reagent mixed liquor has 3 kinds:Bubble mixing, stirring are mixed Even and jet stream mixing.
As shown in Figure 1, the mode of bubble mixing prevalence is that air is squeezed into a closed pressurized tank using air pump, generate Certain positive pressure, this process is known as building positive pressure, during building positive pressure, is supervised by sebific duct and pressure tank connected sensor moment Pressure state in governor pressure tank is until realizing suitable target pressure value.After building positive pressure, pass through piping connection pressure The solenoid valve of power tank and reaction tank uses the mode of discontinuity power on/off, and bubble is generated in reaction tank 1, and bubble is walked from the bottom up, Have reached the purpose of mixing sample.The another way of bubble mixing is the syringe (syringe pump) using larger capacity, is passed through The air of the motion compresses of plunger itself and channel interior, and it is fitted to electricity of the syringe (syringe pump) between reaction tank Magnet valve discontinuity power on/off, to form bubble, mixing sample, as described in Chinese patent CN 104297023 in reaction tank.
The mode stirred and evenly mixed is motor M and stirring rod rigid connection, and stirring rod is in 1 inside of reaction tank and is immersed in sample In mixed liquor, by the rotary motion of motor, stirring rod also rotates accordingly, to stir the sample mixed liquor in reaction tank, It arrived the purpose of mixing.As shown in Figure 2.
Jet stream mixing, also referred to as vortex mixing design special reaction tank 1, its main feature is that reagent inlet 11 and reaction tank Inner wall is tangent, and reagent by the reaction tank that is added to of reagent inlet high speed, and is produced by constant displacement pump or syringe in reaction tank Raw liquid vortex, using vortex by sample and reagent mixed liquor mixing.As shown in Figure 3.
Three of the above mode has the following disadvantages:
Bubble blending manner can be maximum the disadvantage is that bubble mixing well by the sample mixed liquor mixing in reaction tank During can cause sample mixed liquor surface generate foam, foam with bubble number toward rise, climb to no sample Reaction tank top, especially ingredient includes the reagent of surfactant, and foam phenomenon of climbing becomes apparent from, is more serious, cannot keep away What is exempted from is that reagent is generally all added to surfactant, and foam, which climbs, can bring carrying to pollute, if cleaning one under the influence of bad meeting The test result of a sample, and instrument usage time is grown, and can generate crystallization on reaction tank top, crystallization falls off and can also influence Test result, and solenoid valve in fluid path pipe-line system, pump is most probably caused to block clamping stagnation.
It is also good to stir and evenly mix effect, but use occasion is limited, the important component for stirring and evenly mixing mode is that can generate rotation The stirring motor of movement, because reacting the limitation of pool structure, stirring motor, that is, corresponding mechanism can only design above reaction tank, in this way It results in stirring and evenly mixing mode and cannot be used in and extend into reaction tank point by by sampling needle (function be draw and distribution sample) In instrument with sample.
The shortcomings that jet stream mixing is high to the Structural Design Requirement of reaction tank reagent inlet, and even mixed effect is easily by reagent Entrance and reagent play the influence of liquid speed degree.
Therefore, the existing technology needs to be improved and developed.
Utility model content
The purpose of this utility model is to provide a kind of evenly mixing devices for test sample in analyzer reaction tank, it is intended to Solve the problems, such as that existing mixing method is high for the Structural Design Requirement of reaction tank, test effect is impacted.
The technical solution of the utility model is as follows:
A kind of evenly mixing device for test sample in analyzer reaction tank comprising reaction tank, optical measurement module, with And sebific duct;There are multiple reagent inlets, underface to be designed with waste liquid port on the reaction tank, it is close below the reagent inlet The Position Design of reaction tank intracavity bottom has sample channel, and the reagent inlet is described useless for adding in reagent to reaction tank Liquid mouth connects waste liquid module, and the sample channel is connected with optical measurement module by sebific duct;
It is provided with Valve for compressing tubular liner on the sebific duct of connection sample channel and optical measurement module, the Valve for compressing tubular liner is by repeatedly pressing The tight and release sebific duct, which is realized, to be repeatedly sucked out reaction tank by sample liquid and is pushed into reaction tank.
The evenly mixing device for test sample in analyzer reaction tank, wherein the evenly mixing device further includes having The normally open end of three-way solenoid valve, the three-way solenoid valve connects compressed gas;The normal-closed end of the three-way solenoid valve connects air.
The evenly mixing device for test sample in analyzer reaction tank, wherein the Valve for compressing tubular liner tight, bullet for air pressure The sebific duct of spring return type Pneumatic pipe-line valve, the connection sample channel and optical measurement module passes through Valve for compressing tubular liner, is above sebific duct Pneumatic valve core, lower section are resetting spring, and the gas chamber of the Pneumatic pipe-line valve connects the common end of three-way solenoid valve by sebific duct, electricity Magnetic triple valve power on/off makes the gas chamber of Pneumatic pipe-line valve connect compressed gas or air, and spool will when gas chamber leads to compressed gas Hose compresses, and spool unclamps sebific duct by spring return function when gas chamber leads to air, repeatedly switches the break-make electricity condition of three-way solenoid valve It realizes and reaction tank repeatedly is sucked out in sample liquid and is pushed into the mixing operation of reaction tank.
The evenly mixing device for test sample in analyzer reaction tank, wherein the connection sample channel and light The sebific duct for learning measurement module is the flexible hose with resilience and ageing resistance.
A kind of evenly mixing device for test sample in analyzer reaction tank, wherein including reaction tank, sebific duct and waste liquid mould Block;There are multiple reagent inlets, underface to be designed with waste liquid port on the reaction tank, below the reagent inlet, leans on proximal response The Position Design of pond intracavity bottom has sample channel, and the reagent inlet is for adding in reagent to reaction tank, the waste liquid port Connect waste liquid module;
It is provided with Valve for compressing tubular liner on the sebific duct of connection waste liquid port and waste liquid module, the Valve for compressing tubular liner is by repeatedly compressing and pine The sebific duct realization is opened reaction tank repeatedly is sucked out in sample liquid and is pushed into reaction tank.
The evenly mixing device for test sample in analyzer reaction tank, wherein the Valve for compressing tubular liner is pneumatic pressure pipe Valve or electromagnetism Valve for compressing tubular liner.
The evenly mixing device for test sample in analyzer reaction tank, wherein the Valve for compressing tubular liner tight, bullet for air pressure Spring return type Valve for compressing tubular liner, the sebific duct pass through Valve for compressing tubular liner, are pneumatic valve core above sebific duct, and lower section is resetting spring, described pneumatic The gas chamber of Valve for compressing tubular liner connects the common end of three-way solenoid valve by sebific duct, and three-way solenoid valve power on/off makes the gas of Pneumatic pipe-line valve Room connects compressed gas or air, and spool compresses hose when gas chamber leads to compressed gas, and spool relies on bullet when gas chamber leads to air Spring return unclamps sebific duct, and sample liquid is repeatedly sucked out reaction tank and pushed away by the break-make electricity condition realization for repeatedly switching three-way solenoid valve Enter the mixing operation of reaction tank.
The evenly mixing device for test sample in analyzer reaction tank, wherein the connection waste liquid port and waste liquid The sebific duct of module is the flexible hose with resilience and ageing resistance.
The evenly mixing device for test sample in analyzer reaction tank, wherein from reaction tank to Pneumatic pipe-line valve Sebific duct be set as downward arcuate structure.
The beneficial effects of the utility model:The utility model is led to by the way that Valve for compressing tubular liner is arranged on the pipeline for lead to reaction tank The break-make of excessive secondary control Valve for compressing tubular liner is realized and reaction tank repeatedly is sucked out in sample liquid and is pushed into reaction tank, and mixing operation is completed. The device is not only simple in structure and operates and is easy, not high for the design requirement of reaction tank, and the mixed effect completed is very It is good.Not the phenomenon that not will produce the various influence test results that existing mixing method generates.
Description of the drawings
Fig. 1 is existing bubble evenly mixing device structural schematic diagram.
Fig. 2 is existing stirring and evenly mixing device structural schematic diagram.
Fig. 3 is existing jet stream evenly mixing device structural schematic diagram.
Fig. 4 is reaction tank structural schematic diagram provided by the utility model.
Fig. 5 is one structural schematic diagram of the utility model embodiment.
Fig. 6 is two structural schematic diagram of the utility model embodiment.
Specific implementation mode
To keep the purpose of this utility model, technical solution and advantage clearer, clear, develop simultaneously implementation referring to the drawings The utility model is further described in example.
As shown in figure 4, there are two (or multiple) reagent inlets 11 on reaction tank provided by the utility model, underface is set In respect of waste liquid port 12, below reagent inlet, the position of reaction tank inner cavity close to bottom be designed with sample channel 13.Reagent inlet 11 For adding in reagent to reaction tank 1, waste liquid port 12 is for draining the liquid in reaction tank 1, sample channel 13 and optical mode Completely reacted sample is injected into optical measurement module by block by piping connection to realize.
The utility model realizes the mixing of sample mixed liquor using the characteristic of Valve for compressing tubular liner (also referred to as breaking valve).It is connecting The Valve for compressing tubular liner is provided on the pipeline of the sample channel 13 and optical module.Preferably, the Valve for compressing tubular liner is Pneumatic pressure Pipe valve or electromagnetism Valve for compressing tubular liner.
Wherein, the Pneumatic pipe-line valve is that air pressure is tight, spring return function formula, i.e., spool is by hose pressure when gas chamber leads to compressed gas Tightly, spool unclamps sebific duct by spring return function when gas chamber leads to air;Or spring compression, gas return type, this programme are also preferably The tight spring return function formula of air pressure.
The advantages of Valve for compressing tubular liner is:1, valve body itself does not enter valve body itself without runner, sample mixed liquor, liquid; 2, the break-make of flow channel for liquids is realized by way of unclamping or compressing by pressure pipe.
Embodiment one
As shown in figure 5, the Valve for compressing tubular liner is Pneumatic pipe-line valve.Sebific duct passes through Valve for compressing tubular liner 2 to connect reaction tank 1 and optical measurement Module, the part that the sebific duct passes through Valve for compressing tubular liner 2 are the good non-aging flexible hose of resilience, such as Pharmed pipes. The gas chamber 21 of Valve for compressing tubular liner 2 connects the common end of three-way solenoid valve LV1, the normally open end connection pressure of three-way solenoid valve LV1 by sebific duct The normal-closed end of contracting gas, three-way solenoid valve LV1 connects air.Three-way solenoid valve LV1 power on/off makes the gas chamber of Pneumatic pipe-line valve 2 21 connection compressed gas or air.Compressed gas enters the gas chamber 21 of Pneumatic pipe-line valve 2 when three-way solenoid valve LV1 power-off, will Spool 22 presses to flexible hose;When three-way solenoid valve LV1 is powered, the gas chamber 21 of Pneumatic pipe-line valve 2 leads to air, the opposite pressure of gas chamber Power is 0, the return under return spring effect of spool 22, far from flexible hose.Flexible hose is compacted and unclamps two actions and leads The variation of sebific duct cavity volume is caused, liquid is sucked from reaction tank using the cavity volume of this variation, forces the fluid into reaction tank 1, from And realize the mixing of sample mixed liquor.Repeatedly the break-make electricity condition of switching three-way solenoid valve LV1 is realized and repeatedly " is sucked from reaction tank Liquid forces the fluid into reaction tank " action, you can the sample in effective mixing reaction tank, can be according to practical concrete condition Rationally design the break-make switching times of three-way solenoid valve LV1.Certainly, this method is pointed out to design quilt according to the amount of reaction tank mixed liquor The internal diameter and length for the flexible hose that Pneumatic pipe-line valve spool compresses, to reach more effective mixing.
Embodiment two
As shown in fig. 6, the Valve for compressing tubular liner is Pneumatic pipe-line valve.Sebific duct passes through Valve for compressing tubular liner 2 to connect reaction tank 1 and waste liquid mould Block, the part that the sebific duct passes through Valve for compressing tubular liner 2 are the good non-aging flexible hose of resilience, such as Pharmed pipes.For It avoids causing sample mixed liquor in the reaction tank 1 to drop because of gravity, in the present embodiment, from reaction tank to Pneumatic pipe-line valve Sebific duct be set as downward arcuate structure 3.The gas chamber 21 of Valve for compressing tubular liner 2 connects the common end of three-way solenoid valve LV1 by sebific duct, The normally open end of three-way solenoid valve LV1 connects compressed gas, and the normal-closed end of three-way solenoid valve LV1 connects air.Three-way solenoid valve LV1 Power on/off makes the gas chamber 21 of Pneumatic pipe-line valve 2 connect compressed gas or air.Compressed gas when three-way solenoid valve LV1 power-off Into the gas chamber 21 of Pneumatic pipe-line valve 2, spool 22 is pressed into flexible hose;When three-way solenoid valve LV1 is powered, Pneumatic pipe-line valve 2 Gas chamber 21 lead to air, the relative pressure of the gas chamber 21 is 0, the return under return spring effect of spool 22, far from soft balsam Pipe.Flexible hose, which is compacted and unclamps two actions, causes sebific duct cavity volume to change, using the cavity volume of this variation from anti- It answers pond sucking liquid, force the fluid into reaction tank, to realize the mixing of sample mixed liquor.Repeatedly switching three-way solenoid valve LV1 Break-make electricity condition realize repeatedly " from reaction tank sucking liquid, force the fluid into reaction tank " action, you can effective mixing Sample in reaction tank can rationally design the break-make switching times of three-way solenoid valve LV1 according to practical concrete condition.Certainly, originally Method points out the internal diameter and length of the flexible hose compressed by Pneumatic pipe-line valve spool according to the design of the amount of reaction tank mixed liquor, with Reach more effective mixing.
The utility model is compressed using Valve for compressing tubular liner, is unclamped by the variation of flexible hose cavity volume when pressure flexible hose, is inhaled The mode for entering, extruding liquid takes sample mixed liquor in mixing reaction tank.Had using device provided by the utility model following Advantage:
1, this patent provide blending manner not will produce foam, will not also cause the sample mixed liquor of reaction tank climb to Reaction tank top, sample standard deviation is in reaction tank lower middle portion, the problems such as carrying of bubble blending manner will not be brought to pollute, crystallize.
2, the blending manner use occasion that this patent provides does not limit, and device component flexible arrangement does not have the side of stirring and evenly mixing The defect of formula can be used for sampling needle and stretch into the instrument of reaction tank distribution sample.
3, the blending manner that this patent provides is not high to reaction tank Structural Design Requirement, and reagent liquid feeding mode is flexible, can picture Lateral liquid feeding shown in Fig. 3, also can from reaction tank part liquid feeding, the shortcomings that no jet stream mixing.
4, relative to bubble mixing and stir and evenly mix, the blending manner that this this patent of this patent provides also have clean it is easy Advantage, only reaction tank and the sebific duct of contact sample mixed liquor, and rubber tube inner wall, inner surface are smooth, easily clean.
It should be understood that the application of the utility model is not limited to above-mentioned citing, those of ordinary skill in the art are come It says, it can be modified or changed according to the above description, and all these modifications and variations should all belong to the appended power of the utility model The protection domain that profit requires.

Claims (9)

1. a kind of evenly mixing device for test sample in analyzer reaction tank, which is characterized in that including reaction tank, optical measurement Module and sebific duct;There are multiple reagent inlets, underface to be designed with waste liquid port on the reaction tank, under the reagent inlet Side has sample channel, the reagent inlet to be used to add in reagent to reaction tank close to the Position Design of reaction tank intracavity bottom, The waste liquid port connects waste liquid module, and the sample channel is connected with optical measurement module by sebific duct;
Be provided with Valve for compressing tubular liner on the sebific duct of connection sample channel and optical measurement module, the Valve for compressing tubular liner by repeatedly compressing and The sebific duct realization is unclamped reaction tank repeatedly is sucked out in sample liquid and is pushed into reaction tank.
2. the evenly mixing device according to claim 1 for test sample in analyzer reaction tank, which is characterized in that described Evenly mixing device further includes having three-way solenoid valve, and the normally open end of the three-way solenoid valve connects compressed gas;The three-way solenoid valve Normal-closed end connect air.
3. the evenly mixing device according to claim 2 for test sample in analyzer reaction tank, which is characterized in that described The sebific duct of Valve for compressing tubular liner tight, spring return function formula Pneumatic pipe-line valve for air pressure, the connection sample channel and optical measurement module passes through Valve for compressing tubular liner, sebific duct top is pneumatic valve core, and lower section is resetting spring, and the gas chamber of the Pneumatic pipe-line valve connects electromagnetism by sebific duct The common end of triple valve, three-way solenoid valve power on/off make the gas chamber of Pneumatic pipe-line valve connect compressed gas or air, gas chamber Spool compresses hose when logical compressed gas, and spool unclamps sebific duct by spring return function when gas chamber leads to air, repeatedly switches electromagnetism The break-make electricity condition of triple valve, which is realized, to be repeatedly sucked out reaction tank by sample liquid and is pushed into the mixing operation of reaction tank.
4. the evenly mixing device according to claim 3 for test sample in analyzer reaction tank, which is characterized in that described The sebific duct for connecting sample channel and optical measurement module is the flexible hose with resilience and ageing resistance.
5. a kind of evenly mixing device for test sample in analyzer reaction tank, which is characterized in that including reaction tank, sebific duct and Waste liquid module;There are multiple reagent inlets, underface to be designed with waste liquid port on the reaction tank, below the reagent inlet, leans on The Position Design of proximal response pond intracavity bottom has sample channel, the reagent inlet described for adding in reagent to reaction tank Waste liquid port connects waste liquid module by sebific duct;
It is provided with Valve for compressing tubular liner on the sebific duct of connection waste liquid port and waste liquid module, the Valve for compressing tubular liner is by repeatedly compressing and unclamping institute Sebific duct realization is stated reaction tank repeatedly is sucked out in sample liquid and is pushed into reaction tank.
6. the evenly mixing device according to claim 5 for test sample in analyzer reaction tank, which is characterized in that described Evenly mixing device further includes having three-way solenoid valve, and the normally open end of the three-way solenoid valve connects compressed gas;The three-way solenoid valve Normal-closed end connect air.
7. the evenly mixing device according to claim 6 for test sample in analyzer reaction tank, which is characterized in that described Valve for compressing tubular liner tight, spring return function formula Pneumatic pipe-line valve for air pressure, the sebific duct pass through Valve for compressing tubular liner, are pneumatic valve core above sebific duct, under Side is resetting spring, and the gas chamber of the Pneumatic pipe-line valve connects the common end of three-way solenoid valve by sebific duct, and three-way solenoid valve is logical Power-off is so that the gas chamber of Pneumatic pipe-line valve connects compressed gas or air, and spool compresses hose when gas chamber leads to compressed gas, Spool unclamps sebific duct by spring return function when gas chamber leads to air, and repeatedly the break-make electricity condition of switching three-way solenoid valve, which is realized, repeatedly will Sample liquid is sucked out reaction tank and is pushed into the mixing operation of reaction tank.
8. the evenly mixing device according to claim 7 for test sample in analyzer reaction tank, which is characterized in that described The sebific duct for connecting waste liquid port and waste liquid module is the flexible hose with resilience and ageing resistance.
9. the evenly mixing device according to claim 8 for test sample in analyzer reaction tank, which is characterized in that from anti- The sebific duct of Ying Chi to Pneumatic pipe-line valve is set as downward arcuate structure.
CN201721804439.5U 2017-12-21 2017-12-21 A kind of evenly mixing device for test sample in analyzer reaction tank Withdrawn - After Issue CN207786607U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109030368A (en) * 2018-09-08 2018-12-18 重庆科技学院 Micro-fluidic chip application method associated with a kind of and cuvette
CN109939636A (en) * 2017-12-21 2019-06-28 深圳市帝迈生物技术有限公司 A kind of evenly mixing device and method for test sample in analyzer reaction tank

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109939636A (en) * 2017-12-21 2019-06-28 深圳市帝迈生物技术有限公司 A kind of evenly mixing device and method for test sample in analyzer reaction tank
CN109939636B (en) * 2017-12-21 2024-04-19 深圳市帝迈生物技术有限公司 Mixing device and method for test sample in analyzer reaction tank
CN109030368A (en) * 2018-09-08 2018-12-18 重庆科技学院 Micro-fluidic chip application method associated with a kind of and cuvette
CN109030368B (en) * 2018-09-08 2023-06-23 重庆科技学院 Use method of microfluidic chip combined with cuvette

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