CN215711746U - Reagent filling device - Google Patents

Reagent filling device Download PDF

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Publication number
CN215711746U
CN215711746U CN202121773504.9U CN202121773504U CN215711746U CN 215711746 U CN215711746 U CN 215711746U CN 202121773504 U CN202121773504 U CN 202121773504U CN 215711746 U CN215711746 U CN 215711746U
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China
Prior art keywords
reagent
storage tank
liquid storage
reservoir
liquid
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CN202121773504.9U
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Chinese (zh)
Inventor
池书锐
刘俊龙
褚聪
甘小锋
刘治志
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Shenzhen Dymind Biotechnology Co Ltd
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Shenzhen Dymind Biotechnology Co Ltd
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Abstract

The utility model discloses a reagent filling device, which comprises a liquid supply power device, a first liquid storage tank and a second liquid storage tank, wherein the first liquid storage tank and the second liquid storage tank are connected with the liquid supply power device; the second liquid storage tank is provided with a second liquid outlet for providing a reagent for the bubble sensitive module, and the air at the front section is emptied in the process of filling the reagent into the first liquid storage tank, so that the reagent subsequently filled into the second liquid storage tank is ensured to be free of air, and the accuracy of a sample detection result is ensured.

Description

Reagent filling device
Technical Field
The utility model relates to the technical field of sample analyzers, in particular to a reagent filling device of a sample analyzer.
Background
The sample analyzer is the most commonly used blood cell analyzer, which performs statistical analysis on various cells in a blood sample by means of reagents and provides a basis for diagnosis and treatment of doctors. In some high-end sample analyzers, a liquid storage tank is used for caching reagents required for detection, and when the sample analyzer operates, the reagents are directly obtained from the liquid storage tank, so that the detection speed is increased.
Generally, the sample analyzer is provided with an independent reagent filling system to fill and supplement reagents to the liquid storage tank in time, so as to ensure the smooth detection of the sample. The existing reagent filling system mainly has two types of negative pressure liquid suction and quantitative pump liquid pumping, and no matter which type of mode is at the beginning of filling, the front section air can be inevitably pumped into the liquid storage tank, so that the reagent injected into the liquid storage tank contains small bubbles.
Along with the flow of the reagent in the sample analyzer, small bubbles are attached to the wall surface of an internal pipeline of the analyzer or a key detector component, so that the stability of a sample flow path or a light path is influenced; in addition, if the size of the small bubbles is close to the size of the target particles to be detected, the apparatus may be identified incorrectly, which affects the reliability of the detection result.
SUMMERY OF THE UTILITY MODEL
In view of this, a reagent filling device capable of effectively preventing the generation of small bubbles is provided.
A reagent filling device comprises a liquid supply power device, a first liquid storage tank and a second liquid storage tank, wherein the first liquid storage tank and the second liquid storage tank are connected with the liquid supply power device, the first liquid storage tank and the second liquid storage tank are connected in parallel and are alternatively communicated with the liquid supply power device, and a first liquid outlet is formed in the first liquid storage tank and used for providing a reagent for a bubble insensitive module; and a second liquid outlet is formed in the second liquid storage tank and used for providing reagent for the bubble sensitive module.
Further, the liquid supply power device comprises an injector, and the injector is respectively connected with the first liquid storage tank and the second liquid storage tank; or, the liquid supply power device comprises a pressure source and a liquid storage tank, the pressure source is connected with the liquid storage tank through a switching piece, and the liquid storage tank is respectively connected with the first liquid storage tank and the second liquid storage tank.
Further, the liquid supply power device comprises a first pressure source and a quantitative pump, the first pressure source is connected with the quantitative pump through a first switching piece, and the quantitative pump is respectively connected with the first liquid storage tank and the second liquid storage tank.
Further, the dosing pump is connected with the first liquid storage tank and the second liquid storage tank through a second switching piece.
Further, the quantitative pump also comprises a reagent container which is connected to the quantitative pump through a one-way valve.
Further, the reagent container is connected between the second switch and the first liquid storage tank; alternatively, the reagent container is connected between the fixed displacement pump and the second switch.
Further, the reagent container is connected to the first liquid storage tank through the one-way valve, and a break-make piece is connected between the reagent container and the first liquid storage tank.
Further, the first liquid storage tank is also connected with a second pressure source.
Further, a third switching piece is connected between the second pressure source and the first liquid storage tank.
Further, the liquid supply power device fills the second liquid storage tank after the first liquid storage tank is filled with a certain amount of reagent, and air in the liquid supply power device is discharged to the first liquid storage tank in the process of filling the first liquid storage tank.
Compared with the prior art, the utility model is provided with the two liquid storage tanks and fills the reagents into the two liquid storage tanks in sequence, the air at the front section is exhausted in the process of filling the reagents into the first liquid storage tank, the reagents are filled into the second liquid storage tank after the air at the front section is exhausted, the reagents in the second liquid storage tank are ensured not to contain bubbles, and the accuracy of a detection result can be ensured when the reagent is applied to sample detection.
Drawings
FIG. 1 is a schematic structural view of a first embodiment of a reagent filling apparatus according to the present invention.
FIG. 2 is a schematic structural view of a reagent filling apparatus according to a second embodiment of the present invention.
FIG. 3 is a schematic structural view of a reagent filling apparatus according to a third embodiment of the present invention.
Detailed Description
To facilitate an understanding of the utility model, the utility model will now be described more fully with reference to the accompanying drawings. One or more embodiments of the present invention are illustrated in the accompanying drawings to provide a more accurate and thorough understanding of the disclosed embodiments. It should be understood, however, that the present invention may be embodied in many different forms and should not be construed as being limited to the embodiments set forth herein.
The same or similar reference numbers in the drawings correspond to the same or similar parts; in the description of the present invention, it should be understood that if there is an orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", etc. based on the orientation or positional relationship shown in the drawings, it is only for convenience of describing the present invention and simplifying the description, but it is not intended to indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and therefore, the terms describing the positional relationship in the drawings are only used for illustrative purposes and are not to be construed as limiting the present patent, and the specific meaning of the terms may be understood by those skilled in the art according to specific circumstances.
The utility model provides a reagent filling device, which is applied to a sample analyzer to fill a reagent from a reagent container, such as a reagent bottle, into a liquid storage tank for temporary storage, so that the sample analyzer can directly obtain the reagent from the liquid storage tank when carrying out sample detection, such as blood sample detection.
In sample detection, reagents used in different detection items are different, and a plurality of different reagents are also mostly used in one detection, for example, in the detection of a blood sample, the used reagents generally comprise a diluent, a sheath fluid reagent, an immunoturbidimetric reagent, an immunochromatographic reagent and the like, wherein the diluent is used for pretreatment of the blood sample, so that certain high-concentration substances in the blood sample are reduced to a proper range, and the problem that the high-concentration substances are difficult to accurately detect is avoided; the sheath fluid reagent is used for focusing the blood sample to form a sample flow with proper length and stability, and is mainly used for counting white blood cells; the immunoturbidimetric reagent and the immunochromatographic reagent are used for antigen-antibody reaction of blood samples and are mainly used for detecting markers such as CRP, SAA, PCT, IL-6 and the like. It should be understood that the above list is merely illustrative of several commonly used reagents, and the reagents used in the detection of a sample are not limited thereto.
Fig. 1 is a schematic structural diagram of a reagent filling apparatus according to an embodiment of the present invention, which includes a reagent container 20, a metering pump 22 connected to the reagent container 20, a first pressure source 24 for powering the metering pump 22, a first reservoir 26, and a second reservoir 28. All the devices can be connected through pipelines such as flexible rubber tubes. The metering pump 22, the first pressure source 24 and the associated piping together form a liquid supply power device that draws the reagent in the reagent container 20 and fills the first liquid storage tank 26 or the second liquid storage tank 28. The first pressure source 24 may be a gas source, an air pump, a syringe, etc. for providing pressure, and the first pressure source 24 is shown as a gas source, including a positive pressure gas source 24a and a negative pressure gas source 24b, wherein the negative pressure gas source 24b is used for providing a negative pressure P2 to make the quantitative pump 22 suck the reagent from the reagent container 20, and the positive pressure gas source 24a is used for providing a positive pressure P1 to make the quantitative pump 22 pour the sucked reagent into the first reservoir 26 or the second reservoir 28.
The reagent container 20 is used for storing reagents required for the test, is bulky, has a large dosage, and is generally disposed outside the sample analyzer. The first reservoir 26 and the second reservoir 28 are disposed within the sample analyzer and have a volume that is reduced by an order of magnitude relative to the volume of the reagent container 20, typically only 5-10 ml. The reagent container 20 and the like are schematically shown in the drawings by a block, and the shape, size, and the like of each element in the drawings are not limited to actual ones. Generally, the metering pump 22 is disposed adjacent to the first and second reservoirs 26, 28, and the length of the connecting line between the metering pump 22 and the external reagent container 20 is much greater than the length of the connecting line between the metering pump 22 and the internal first and second reservoirs 26, 28. Thus, in the process of sample detection, the detection module obtains the reagent from the first liquid storage tank 26 and the second liquid storage tank 28, so that the length of the reagent flow path can be greatly reduced, and the progress of sample detection can be accelerated.
In the illustrated embodiment, the positive pressure gas source 24a and the negative pressure gas source 24B are connected to the fixed displacement pump 22 through a first switching element 30, and the first switching element 30 may be a three-way solenoid valve or the like, and includes a first port a, a second port B, and a third port C, where the first port a is connected to the negative pressure gas source 24B, the second port B is connected to the positive pressure gas source 24a, and the third port C is connected to the fixed displacement pump 22. When the first switch member 30 is closed, the port A, C is connected, the port B, C is disconnected, and the negative pressure gas source 24b and the fixed displacement pump 22 are connected so that the fixed displacement pump 22 can suck the reagent from the reagent container 20; conversely, when the first switch member 30 is opened, the port B, C is connected, the port A, C is disconnected, and the positive pressure gas source 24a and the fixed displacement pump 22 are connected so that the fixed displacement pump 22 can pump the sucked reagent into the first and second reservoirs 26, 28.
Before sample detection is carried out, a sample analyzer using the reagent filling device of the present invention fills a reagent from the first reagent container 20 to the first and second liquid storage tanks 26 and 28 through the quantitative pump 22 under the action of positive and negative air pressure of the first pressure source 24; thereafter, during sample testing, the detection module obtains reagents directly from the first and second reservoirs 26, 28. In the above embodiment, the fixed displacement pump 22 is alternatively communicated with the positive pressure air source 24a and the negative pressure air source 24b through the three-way solenoid valve, and the positive pressure air source 24a and the negative pressure air source 24b form linkage, which is simpler in operation. It should be understood that the first switching element 30 may also be composed of two-way valves and a three-way joint, one port of the three-way joint is connected to the positive pressure gas source 24a through the two-way valve, one port is connected to the negative pressure gas source 24b through the other two-way valve, and one port is connected to the quantitative pump 22, and the communication between the quantitative pump 22 and the positive pressure gas source 24a and the negative pressure gas source 24b can also be switched, so that the quantitative pump 22 can suck the reagent in the reagent container 20 or fill the first and second liquid storage tanks 26 and 28 with the reagent.
In this embodiment, the first tank 26 and the second tank 28 are arranged in parallel and connected to the fixed displacement pump 22 via a second switching member 32. The second switching member 32 is preferably a three-way solenoid valve or the like, and includes a first port D, a second port E, and a third port F, wherein the first port D is connected to the second tank 28, the second port E is connected to the first tank 26, and the third port F is connected to the fixed displacement pump 22. The quantitative pump 22 is alternatively communicated with the first liquid storage tank 26 and the second liquid storage tank 28 through the second switching piece 32, when the second switching piece 32 is closed, the interface F, E is communicated, the interface F, D is disconnected, and the quantitative pump 22 and the first liquid storage tank 26 are communicated so that the quantitative pump 22 can fill the first liquid storage tank 26 with reagent; conversely, when the second switch 32 is opened, the port F, D is connected, the port F, E is disconnected, and the quantitative pump 22 and the second reservoir 28 are connected so that the quantitative pump 22 can fill the second reservoir 28 with the reagent.
In this embodiment, the second port B of the second switching member 32, the reagent container 20 and the first liquid storage tank 26 are connected by a three-way joint 34, a first on-off member 36 is disposed on a connection pipeline between the three-way joint 34 and the first liquid storage tank 26, and a second on-off member 38, such as a one-way valve, is disposed on a connection pipeline between the three-way joint 34 and the reagent container 20. The first on-off member 36 may be a two-way solenoid valve that disconnects the three-way connector 34 from the first reservoir 26 when closed and communicates the three-way connector 34 with the first reservoir 26 when open. The second shut-off member 38 keeps the flow path of the reagent container 20 to the three-way joint 34 in communication and the flow path of the three-way joint 34 to the reagent container 20 in shut-off. That is, when the second switch 32 is closed, the connection between the three-way joint 34 and the first reservoir tank 26 is disconnected when the first shut-off member 36 is closed, and at this time, only the flow path between the quantitative pump 22 and the reagent container 20 is connected, and the reagent flows to the quantitative pump 22; if the first cut-off member 36 is opened, the three-way joint 34 is connected to the first reservoir 26, and the reagent can only flow from the quantitative pump 22 to the first reservoir 26 by the one-way conduction of the second cut-off member 38.
The first liquid storage tank 26 is used for temporarily storing reagents with bubbles, and a first liquid outlet 27 is formed at the bottom of the first liquid storage tank and is used for being connected with a bubble insensitive module of the sample analyzer; the second reservoir 28 is used for temporarily storing the reagent without bubbles, and a second liquid outlet 29 is formed at the bottom of the second reservoir and is used for connecting with a bubble sensitive module of the sample analyzer. Preferably, first reservoir 26 is also connected to a second pressure source 40, and second pressure source 40 may be a gas source or the like. During the process of filling the first reservoir 26 with reagent, the air source 40 provides a negative pressure P3 to accelerate the filling of reagent from the dosing pump 22 into the first reservoir 26; during the outward delivery of reagent from first reservoir 26, positive pressure P4 is provided by gas source 40 to accelerate the output of reagent. Preferably, a third switching member 42 is connected between second pressure source 40 and first tank 26, and third switching member 42 may be a three-way solenoid valve or the like for selectively connecting positive pressure P4 or negative pressure P3 to first tank 26.
It should be noted that: the bubble sensitive module in the utility model refers to a detection module such as a flow chamber, an impedance back pool and the like of a sample analyzer, wherein the processing result of the module on a reagent is influenced by bubbles contained in the reagent, and a second liquid storage tank 28 provides the reagent for reaction, detection or cleaning; a bubble insensitive module is a module in which the presence of bubbles in the reagent does not affect the results of the processing of the reagent by the module, such as a reaction cell, swab, etc. of a sample analyzer, to which first reservoir 26 provides the reagent for washing.
When the reagent is filled, firstly, a certain amount of reagent is filled into the first liquid storage tank 26, and in the filling process, front-section air, including air inside the quantitative pump 22 and air in a connecting pipeline between the quantitative pump 22 and the reagent container 20, is discharged into the first liquid storage tank 26 so that the reagent in the first liquid storage tank 26 is provided with small bubbles; the second reservoir 28 is refilled with reagent after the air in the previous section has been exhausted, ensuring that the reagent in the second reservoir 28 is free of small air bubbles. It should be understood that the reagent in the second reservoir 28 is not absolutely free of small bubbles, but has a low bubble content that does not affect the accuracy of the sample measurement, since the reagent itself will have a small amount of dissolved air, and the connection between the dosing pump 22 and the second reservoir 28 will also have a very small amount of dissolved air, but will be negligible relative to the air in the connection between the dosing pump 22 and the reagent container 20.
Fig. 2 shows a second embodiment of the reagent filling apparatus of the present invention, which differs from the first embodiment mainly in the connection of the reagent vessel 20. In this embodiment, the reagent container 20 is connected between the quantitative pump 22 and the second switching member 32, and the three pipes may be connected by a three-way joint 34. Specifically, the first port D of the second switching member 32 is directly connected to the second tank 28, the second port E is connected to the first tank 26 through the first break-off member 36, and the third port F is connected to the three-way joint 34. When the first switch 30 is closed, the second switch 32 and the first on/off member 36 are closed, and the quantitative pump 22 sucks the reagent from the reagent container 20. When the first switching member 30 is opened, the first on-off member 36 is first opened, and the quantitative pump 22 fills the first reservoir tank 26 with the reagent; then, the first on-off member 36 is closed and the second switching member 32 is opened, the quantitative pump 22 fills the reagent into the second liquid storage tank 28, and the air in the front section is discharged into the first liquid storage tank 26, so that the reagent in the second liquid storage tank 28 is ensured to be free of air bubbles. In other embodiments, the reagent container 20 may be connected to the conduit between the dosing pump 22 and the second reservoir 28 by a three-way connection 34, so long as it is in communication with the dosing pump 22.
Fig. 3 shows a third embodiment of the reagent filling apparatus of the present invention, which is different from the second embodiment mainly in the second switching member 36. In this embodiment, the second switching member 36 is composed of a first two-way valve 361, a second two-way valve 363, and a three-way joint 365, wherein the three-way joint 365 is connected in series between the fixed displacement pump 22 and the first and second two-way valves 361 and 363, the first liquid storage tank 26 is connected to the first two-way valve 361, and the second liquid storage tank 28 is connected to the second two-way valve 363. The reagent container 20 is connected between the metering pump 22 and the three-way joint 365. When the first switching member 30 is closed, the first two-way valve 361 and the second two-way valve 363 are closed, and the quantitative pump 22 sucks the reagent from the reagent container 20. When the first switching member 30 is opened, the first two-way valve 361 is first opened, and the quantitative pump 22 injects the reagent into the first liquid storage tank 26; then, the first two-way valve 361 is closed and the second two-way valve 363 is opened, the quantitative pump 22 injects the reagent into the second liquid storage tank 28, and the air in the front section is discharged to the first liquid storage tank 26, so that the reagent in the second liquid storage tank 28 is ensured not to contain bubbles.
The utility model is provided with two liquid storage tanks 26, 28, reagent is filled into the two liquid storage tanks 26, 28 in sequence, air in a connecting pipeline between the quantitative pump 22 and the reagent container 20 is emptied in the process of filling the reagent into the first liquid storage tank 26, and the reagent is filled into the second liquid storage tank 28 after the air in the front section is emptied. During sample detection, the second liquid storage tank 28 outputs a reagent without bubbles to a reaction module, a detection module and the like of the sample analyzer, so that subsequent detection is not influenced by bubbles, and the accuracy of a detection result is ensured; before or after the sample is detected, the reagent with bubbles, such as diluent, in the first liquid storage tank 26 can be output to clean the connecting pipeline of the sample analyzer, so that the influence of residual sample liquid on the detection accuracy is avoided. Of course, if the reagent is not suitable for cleaning the pipeline, the reagent can be directly discharged into the waste liquid storage module of the sample analyzer.
The reagent filling process comprises the following steps: first, the first storage tank 26 is filled with the reagent to exhaust the air, i.e., the air in the front section, including the air inside the quantitative pump 22 and the air in the connection pipeline between the quantitative pump 22 and the reagent container 20, is discharged into the first storage tank 26; secondly, the second reservoir 28 is filled with reagent, i.e. after the air in the front section has been exhausted, the reagent is filled into the second reservoir 28 for temporary storage.
Specifically, filling first reservoir 26 with reagent to vent includes the steps of: 1) the first switching piece 30 is closed to connect the negative pressure air source 24b and the quantitative pump 22, the second switching piece 32 is closed to connect the quantitative pump 22 and the reagent container 20, and the quantitative pump 22 sucks the reagent from the reagent container 20 under the action of the negative pressure P1; 2) the first switch 30 is opened to connect the positive pressure gas source 24a to the quantitative pump 22, the first cut-off member 36 is opened to connect the quantitative pump 22 to the first reservoir tank 26, and the quantitative pump 22 pumps the aspirated reagent into the first reservoir tank 26 under the action of the positive pressure P2. During the process of sucking up reagent and filling the first liquid storage tank 26, the quantitative pump 22 discharges air into the first liquid storage tank 26 with the reagent. In order to ensure that the air in the front section can be completely discharged, the steps S11 and S12 can be repeated for a plurality of times, such as 3-5 times.
Specifically, the filling of the second reservoir 28 with reagent includes the steps of: 1) the first switching piece 30 is closed to connect the negative pressure air source 24b and the quantitative pump 22, the second switching piece 32 is closed to connect the quantitative pump 22 and the reagent container 20, and the quantitative pump 22 sucks the reagent from the reagent container 20 under the action of the negative pressure P1; 2) the first switch 30 is opened to connect the positive pressure air source 24a and the quantitative pump 22, the second switch 32 is opened to connect the quantitative pump 22 and the second reservoir 28, and the quantitative pump 22 pumps the sucked reagent to the second reservoir 28 under the action of the positive pressure P2. According to the specific content of the sample detection, the dosage of the reagent can be estimated, and the step of filling the reagent into the second liquid storage tank 28 by the reagent dosage quantitative pump 22 can be performed once or repeated for multiple times until the reagent injected into the second liquid storage tank 28 can meet the requirement of the sample detection or the second liquid storage tank 28 is full.
In the above embodiment, the quantitative pump 22 is used in combination with the first pressure source 20 to form a liquid supply power device, so that the amount of the reagent injected into the liquid storage tanks 26 and 28 can be better controlled. In some embodiments, the liquid supply power device can be composed of a motor and an injector, the injector is respectively connected with the first liquid storage tank and the second liquid storage tank, and the motor is used as a power source to drive the injector to suck liquid or pour liquid; or, the liquid supply power device comprises a pressure source and a liquid storage tank; or the liquid supply power device is composed of an injector independently, and the liquid suction or injection operation is performed through manual operation of a user; or, the liquid supply power device may be a combination of a pressure source and a liquid storage tank, the liquid storage tank is respectively connected with the first liquid storage tank and the second liquid storage tank, and the pressure source is connected with the liquid storage tank through a switching member, which is not limited to the specific embodiment. The quantitative pump, the injector, the liquid storage tank and the like form a storage structure of the liquid supply power device, and can temporarily store the absorbed reagent; the pressure source, motor, syringe, etc. form the power source for the liquid supply power device to draw the reagent in the reagent container 20 to the storage structure and to fill the first liquid storage tank 26 and the second liquid storage tank 28 in sequence.
According to the utility model, by setting the perfusion sequence, the reagents are firstly perfused into the first and second liquid storage tanks 26 and 28, the reagent sucked by the quantitative pump 22 for a plurality of times and the front-section air are injected into the first liquid storage tank 26, the reagent sucked by the quantitative pump 22 after the front-section air is exhausted is injected into the second liquid storage tank 28, the reagent injected into the second liquid storage tank 28 is ensured not to contain air bubbles, and the accuracy of the detection result can be ensured when the reagent is subsequently applied to quantitative reaction of sample detection; the reagent in the first liquid storage tank 26 containing the air at the front section can be used for cleaning the connecting pipeline, so that the best use is achieved and the waste is avoided. The reagent containing bubbles and the reagent not containing bubbles are respectively stored by the two liquid storage tanks 26 and 28, and the reagent is simple and easy to construct; the two liquid storage tanks 26 and 28 are sequentially filled by controlling the on-off of the flow paths of the two liquid storage tanks 26 and 28 in the filling process of the reagent, so that the separation of the reagent containing air bubbles is completed, the operation is simple and convenient, the air bubble separation effect is good, and the reliability of sample detection is ensured.
It should be noted that the present invention is not limited to the above-mentioned embodiments, and other changes and modifications can be made by those skilled in the art according to the spirit of the present invention, and these changes and modifications made according to the spirit of the present invention should be included in the scope of the present invention as claimed.

Claims (10)

1. A reagent filling device is characterized by comprising a liquid supply power device, a first liquid storage tank and a second liquid storage tank, wherein the first liquid storage tank and the second liquid storage tank are connected with the liquid supply power device; and a second liquid outlet is formed in the second liquid storage tank and used for providing reagent for the bubble sensitive module.
2. The reagent filling device of claim 1, wherein the fluid supply power device comprises a syringe, the syringe being connected to the first reservoir and the second reservoir, respectively; or, the liquid supply power device comprises a pressure source and a liquid storage tank, the pressure source is connected with the liquid storage tank through a switching piece, and the liquid storage tank is respectively connected with the first liquid storage tank and the second liquid storage tank.
3. The reagent filling device of claim 1, wherein the liquid supply power device comprises a first pressure source and a dosing pump, the first pressure source is connected with the dosing pump through a first switching piece, and the dosing pump is respectively connected with the first liquid storage tank and the second liquid storage tank.
4. The reagent filling device of claim 3, wherein the dosing pump is connected to the first reservoir and the second reservoir by a second switch.
5. The reagent filling device of claim 4, further comprising a reagent container connected to the dosing pump by a one-way valve.
6. The reagent filling apparatus of claim 5, wherein the reagent container is connected between the second switch and the first reservoir; alternatively, the reagent container is connected between the fixed displacement pump and the second switch.
7. The reagent filling device of claim 5, wherein the reagent container is connected to the first reservoir via the one-way valve, and a shut-off member is connected between the reagent container and the first reservoir.
8. The reagent filling apparatus of claim 1, wherein the first reservoir is further coupled to a second pressure source.
9. The reagent filling apparatus of claim 8, wherein a third switch is connected between the second pressure source and the first reservoir.
10. The reagent filling apparatus of any of claims 1-9 wherein the liquid supply power device fills the second reservoir after the first reservoir is filled with a dose of reagent, and wherein air within the liquid supply power device is vented to the first reservoir during filling of the first reservoir.
CN202121773504.9U 2021-07-30 2021-07-30 Reagent filling device Active CN215711746U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114460326A (en) * 2022-04-11 2022-05-10 深圳市帝迈生物技术有限公司 Reagent replenishing device and reagent replenishing method for sample analyzer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114460326A (en) * 2022-04-11 2022-05-10 深圳市帝迈生物技术有限公司 Reagent replenishing device and reagent replenishing method for sample analyzer

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