CN207352024U - The detection box of quick detection cloth disease IgM and IgG - Google Patents
The detection box of quick detection cloth disease IgM and IgG Download PDFInfo
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- CN207352024U CN207352024U CN201721354541.XU CN201721354541U CN207352024U CN 207352024 U CN207352024 U CN 207352024U CN 201721354541 U CN201721354541 U CN 201721354541U CN 207352024 U CN207352024 U CN 207352024U
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Abstract
A kind of detection box of quick detection cloth disease IgM and IgG, it is characterised in that：Include upper cover (3) and back box (1),Upper cover (3) can be covered in back box (1),The upper lid is equipped with observation window (5) and well (9),The patch (12) for being capable of block well (9) is equipped with the outside of the well (9),Sample storage pond (10) are equipped with the back box (1),Sample storage pond (10) is located at below the well (9) of upper cover (3),Partition plate (11) is equipped with sample storage pond (10),Sample storage pond (10) are divided into two sample cells in left and right by partition plate (11),Sample cell is connected with liquid barrier pad (8),Liquid barrier pad (8) rear is equipped with sample pad (7) successively,Gold-labelled pad (6),Nitrocellulose filter (4) and blotting paper (2),The detection reagent that can detect IgM and IgG is respectively equipped with the gold-labelled pad (6) of described the right and left,The nitrocellulose filter (4) is located at the lower section of observation window (5).The utility model has the features such as simple in structure, easy to use, compact structure, easy to carry.
Description
Technical field
The utility model belongs to crop-harvesting mechanism, especially a kind of detection box of quick detection cloth disease IgM and IgG.
Background technology
Brucellosis (Brucellosis, abbreviation cloth disease) is a kind of serious harm people and animal health " repeatability "
(reemerging) infectious diseases common to human beings and animals, is《People's Republic of China's law on the prevention and control of infectious diseases》The Class B of middle regulation management infects
Disease.The whole world there are about this popular disease of 170 countries and regions.In recent years, people and animals' epidemic situation of brucellosis is worldwide equal
There is rebound momentum, and be in sustainable growth situation, grow in intensity.China is in addition to Macao and Taiwan epidemic situation are unknown, all provinces
Cloth disease case has been reported or found to level unit, and one it has been observed that case will increase quickly.In the past 20 years, the cloth in China
Case continues to increase, and after 1998, the surging rise of people's epidemic situation of brucellosis, number of the infected rises year by year, 2014 annual reports
Accuse new cases, incidence 3.14/10 ten thousand, over the previous year same period rising 18.91%.The Major Epidemic area of cloth disease concentrates on China
" three Norths " area, i.e. northeast, North China and northwest are particularly acute with the ground such as the Inner Mongol, Xinjiang, Heilungkiang, Jilin epidemic situation.
Brucellosis is a kind of systemic disease, and course for the treatment of length is presented in the diagnose and treat after infection not in time more, in advance
Poor afterwards, the features such as lost work is big, and hygienic consumption demand is high, great economic loss is caused to personal, family and society, very
Drive into poverty by medical crises to what is thereby resulted in, phenomenon of backing into poverty by medical crises is very prominent, it has also become threaten the important of economic development and social stability
One of factor.Since cloth patient clinical manifestation is without specificity, clinical misdiagnosis easily misses cloth patient and most preferably controls acute stage
The treatment phase, so that it is difficult the chronic phase cured to be changed into, causes cloth Quality of Life of Patients with Senile Hypertension degradation.At present, the diagnosis of cloth disease
Laboratory diagnosis is depended on, mainly including following several method：1. bacterial cultivation；2. serological diagnostic method：Tiger is red
Tablet aggegation is tested, buffering flat plates aggegation experiment, complement fixation test, enzyme-linked immunosorbent assay, fluorescence polarization experiment, milk
Ring-type is tested, brucellin skin experiment etc..Though pathogen separation method is accurate, time-consuming, and positive rate is low, to separating ring
Border requires high.Rose bengal precipitation test and tube agglutination test because it is easy to operate, without special installation, become China and examine at present
Survey people cloth disease and the common method of domestic animal cloth disease, but exist judge result subjectivity is strong, easily there is false positive or missing inspection etc.
Deficiency.
Therefore, a kind of detection kit with the features such as simple in structure, easy to use, compact structure, easy to carry carries
Go out.
The content of the invention
The purpose of this utility model is that, there is provided a kind of simple in structure, easy to use, compact structure, it is portable fast
The detection box of speed detection cloth disease IgM and IgG.
The utility model discloses a kind of detection box of quick detection cloth disease IgM and IgG, it is characterised in that：Include upper cover
(3) can be covered in back box (1) with back box (1), upper cover (3), the upper lid is equipped with observation window (5) and well (9), institute
The patch (12) for being equipped with the outside of well (9) and being capable of block well (9) is stated, sample storage pond (10) are equipped with the back box (1), is stored up
Sample pond (10) is located at below the wells (9) of upper cover (3), is equipped with partition plate (11) in sample storage pond (10), and partition plate (11) is by sample storage pond
(10) it is divided into two sample cells in left and right, sample cell is connected with liquid barrier pad (8), and liquid barrier pad (8) rear is equipped with sample pad successively
(7), gold-labelled pad (6), nitrocellulose filter (4) and blotting paper (2), are respectively equipped with energy in the gold-labelled pad (6) of described the right and left
The detection reagent of IgM and IgG is enough detected, the nitrocellulose filter (4) is located at the lower section of observation window (5).
In actual work：Patch (12) is taken out first, sample is added dropwise to sample storage pond (10), partition plate from well (9)
(11) sample is separated into the sample cell of both sides, sample can be reacted with Test paper afterwards, and final detection result can be fine in nitric acid
Shown on the plain film (4) of dimension, the testing result from observation window (5).
Since the detection reagent in the gold-labelled pad (6) of sample cell side is different, it can be carried out by being once loaded
A variety of detections, while saving work efficiency, avoid the waste of repeated sampling.
As an improvement, the partition plate (11) is Y-shaped or "+" type.When actually detected, several samples can be added, at the same time
Detection.
The liquid barrier pad (8) of the sample cell both sides is different to same sample flow absorbability.
Compared with prior art, the utility model has simple in structure, easy to use a, compact structure, easy to carry etc. excellent
Point.
Brief description of the drawings
Fig. 1 is the utility model main structure diagram.
Fig. 2 is the utility model back box and upper cover separated position structure diagram.
Fig. 3 is back box overlooking the structure diagram.
Shown in figure：1 is back box, and 2 be blotting paper, and 3 be upper cover, and 4 be nitrocellulose filter, and 5 be observation window, and 6 be golden mark
Pad, 7 be sample pad, and 8 be liquid barrier pad, and 9 be well, and 10 be sample storage pond, and 11 be partition plate, and 12 be patch, and 13 be holding section.
Embodiment
Embodiment 1：With reference to Fig. 1~3, for the structural scheme of mechanism of the utility model embodiment 1, present embodiment discloses one kind
Once quick detection people's brucellosis IgG and the test card of IgM antibody, the test card include upper cover, are installed on sample-adding at the same time
It is used for detecting test strips, the back box of brucellosis anti-igg and IgM antibody in back box.The back box includes fixed test paper
The latch of bar, on the sample storage pond at center, sample storage pond covered with filter sample pad, sample storage pond midpoint has tabula line to be divided into two and half samples
Product pond, the liquid barrier pad 1 for being liquid barrier pad card slot and being positioned in two card slots, liquid barrier pad 2 with half sample cell unicom, two blocking solutions
Pad has differences same sample flow absorbability, reaches the different sample requirement amount of two test strips；The test strips bag
Include detection people's brucellosis IgG and detect people's brucellosis IgM antibody test strips, each test paper include sample pad,
Gold-labelled pad, nitrocellulose filter and blotting paper, be coated with the nitrocellulose filter of two kinds of test strips brucellergen and
Sheep anti mouse monoclonal antibody；Detection people's brucellosis IgG antibody test strips on gold-labelled pad spraying be colloid gold label mouse it is anti-human
IgG monoclonal antibodies, that detect the spraying of the gold-labelled pad in people's brucellosis IgG antibody test strips is the anti-human IgM of mouse of colloid gold label
Monoclonal antibody；The upper cover is equipped with two observation windows and a well, and well must be aligned and circular sample storage pond central point.By
The requirement of sample is had differences in the test strips of people's brucellosis IgG and IgM antibody, people's brucellosis IgG test paper
Bar only needs the sample size of 60ul to reach the target of detection, and people's brucellosis IgM test strips need the sample of 180ul
Amount, this traditional method is to be loaded at twice, and the utility model patent is by setting two isometric sample storage ponds to add difference
The liquid barrier pad of water absorption achievees the purpose that to solve once to be loaded different test strips sample sizes, the utility model have detection it is quick,
It is simple, convenient it is directly perceived, improve product quality
Namely there is the contact history two to three days of brucella in brucellosis infection early stage, just generating cloth in vivo
The IgM antibody of Shandong Salmonella, but human body only has the symptoms such as fever, fatigue at this time, if treatment can cure rehabilitation completely in time at this time；
Continue to be transformed into for 5-7 days chronic, produce the IgG antibody of brucella, state of an illness decrease in vivo, symptom is afternoon low fever, tired
Labor cannot cure completely at this time, and patient becomes permanent carrier, in detection cloth disease；Therefore urgent clinical needs can detect cloth at the same time
The detection card of sick IgM and IgG, being capable of the different therapeutic schemes of testing result formulation.Infect and cloth is produced in the human body of brucellosis
Sick IgM and IgG differ greatly, and 5-10ul is only needed for cloth disease IgG antibody, and cloth disease IgM needs 40ul samples, are disposably adding
Sample solution problem when never equal samples needs, therefore the test card.
The purpose of this utility model is to provide a kind of simple in structure, and easy to use, disposable sample-adding can detect people's cloth at the same time
The Test paper card of sick IgG and IgM.
The utility model is characterized in that：The test card includes upper cover, is installed in back box for detecting brucellosis
The test strips of anti-igg and IgM antibody, back box.The back box includes the latch of fixed test strips, the sample storage positioned at center
Covered with filter sample pad on pond, sample storage pond, sample storage pond midpoint has tabula line to be divided into two and half sample storage ponds, is with half sample storage pond unicom
Liquid barrier pad card slot and liquid barrier pad 1, the liquid barrier pad 2 being positioned in two card slots, two liquid barrier pads are to same sample flow absorbability
Have differences, reach the different sample requirement amount of two test strips；The test strips include detection people's brucellosis IgG and
The test strips of people's brucellosis IgM antibody are detected, each test paper includes sample pad, gold-labelled pad, nitrocellulose filter and suction
Water paper, is coated with brucellergen and sheep anti mouse monoclonal antibody on the nitrocellulose filter of two kinds of test strips；Detect people's cloth Lu Shi
What the gold-labelled pad in bacterium disease IgG antibody test strips sprayed is the mouse anti-human igg monoclonal antibody of colloid gold label, detects people's brucellosis
What the gold-labelled pad in IgG antibody test strips sprayed is the anti-human IgM monoclonal antibodies of mouse of colloid gold label；The upper cover is equipped with two sights
Window and a well are examined, well must be aligned and circular sample storage pond central point.
As an improvement, being equipped with a well, the sample storage pond central dividing line face of the well and back box can be once
Sample-adding, two parts of equalization are divided into the requirements in two and half sample storage ponds, meeting disposable two detections of sample-adding by sample flow.
As an improvement, what is be connected in half sample storage pond of back box is liquid barrier pad card slot and the liquid barrier pad being positioned in two card slots
1st, liquid barrier pad 2, two liquid barrier pads have differences the absorbability of liquid sample, can be in two kinds of test strips to different samples
Demand.
As an improvement, two observation windows are designed with upper lid, people's brucellosis IgG and detection people's brucellosis
The equal observable of testing result of IgM antibody.
Claims (3)
- A kind of 1. detection box of quick detection cloth disease IgM and IgG, it is characterised in that：Include upper cover (3) and back box (1), upper cover (3) can cover in back box (1), the upper lid is equipped with observation window (5) and well (9), is set on the outside of the well (9) There is the patch (12) for being capable of block well (9), be equipped with sample storage pond (10) in the back box (1), sample storage pond (10) are located at upper cover (3) below well (9), partition plate (11) is equipped with sample storage pond (10), sample storage pond (10) are divided into left and right two by partition plate (11) A sample cell, sample cell are connected with liquid barrier pad (8), and liquid barrier pad (8) rear is equipped with sample pad (7), gold-labelled pad (6), nitric acid successively Cellulose membrane (4) and blotting paper (2), are respectively equipped with the inspection that can detect IgM and IgG in the gold-labelled pad (6) of described the right and left Test agent, the nitrocellulose filter (4) are located at the lower section of observation window (5).
- 2. the detection box of quick detection cloth disease IgM and IgG according to claim 1, it is characterised in that：The partition plate (11) For Y-shaped or "+" type.
- 3. the detection box of quick detection cloth disease IgM and IgG according to claim 1, it is characterised in that：Sample cell both sides Liquid barrier pad (8) is different to same sample flow absorbability.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721354541.XU CN207352024U (en) | 2017-10-19 | 2017-10-19 | The detection box of quick detection cloth disease IgM and IgG |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721354541.XU CN207352024U (en) | 2017-10-19 | 2017-10-19 | The detection box of quick detection cloth disease IgM and IgG |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109911425A (en) * | 2019-01-29 | 2019-06-21 | 新疆维吾尔自治区人民医院 | A kind of pulmonary tuberculosis detection kit and its application |
| CN110082518A (en) * | 2019-06-10 | 2019-08-02 | 江南大学 | A kind of Sidestream chromatography test strips detection boxcar |
| CN115166239A (en) * | 2022-08-02 | 2022-10-11 | 中国农业科学院北京畜牧兽医研究所 | Integrated antibody detection test strip for primary screening and accurate diagnosis of bovine brucellosis |
-
2017
- 2017-10-19 CN CN201721354541.XU patent/CN207352024U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109911425A (en) * | 2019-01-29 | 2019-06-21 | 新疆维吾尔自治区人民医院 | A kind of pulmonary tuberculosis detection kit and its application |
| CN110082518A (en) * | 2019-06-10 | 2019-08-02 | 江南大学 | A kind of Sidestream chromatography test strips detection boxcar |
| CN110082518B (en) * | 2019-06-10 | 2024-04-09 | 江南大学 | Lateral flow chromatography test strip detects conversion box |
| CN115166239A (en) * | 2022-08-02 | 2022-10-11 | 中国农业科学院北京畜牧兽医研究所 | Integrated antibody detection test strip for primary screening and accurate diagnosis of bovine brucellosis |
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