CN110082518B - Lateral flow chromatography test strip detects conversion box - Google Patents
Lateral flow chromatography test strip detects conversion box Download PDFInfo
- Publication number
- CN110082518B CN110082518B CN201910496846.1A CN201910496846A CN110082518B CN 110082518 B CN110082518 B CN 110082518B CN 201910496846 A CN201910496846 A CN 201910496846A CN 110082518 B CN110082518 B CN 110082518B
- Authority
- CN
- China
- Prior art keywords
- box
- test paper
- test strip
- lateral flow
- box cover
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000012360 testing method Methods 0.000 title claims abstract description 103
- 238000004587 chromatography analysis Methods 0.000 title claims abstract description 35
- 238000006243 chemical reaction Methods 0.000 title claims abstract description 30
- 238000001514 detection method Methods 0.000 claims abstract description 45
- 210000001503 joint Anatomy 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 8
- 238000013461 design Methods 0.000 abstract description 4
- 230000007547 defect Effects 0.000 abstract description 2
- 239000000123 paper Substances 0.000 description 41
- 239000000523 sample Substances 0.000 description 14
- 239000012528 membrane Substances 0.000 description 11
- 239000012488 sample solution Substances 0.000 description 5
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 4
- 239000007853 buffer solution Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 230000000007 visual effect Effects 0.000 description 3
- 239000000020 Nitrocellulose Substances 0.000 description 2
- 230000000975 bioactive effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000011491 glass wool Substances 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 229920001220 nitrocellulos Polymers 0.000 description 2
- 150000003384 small molecules Chemical class 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000005206 flow analysis Methods 0.000 description 1
- 238000011062 flow through chromatography Methods 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 239000011087 paperboard Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
- G01N33/521—Single-layer analytical elements
Abstract
A lateral flow chromatography test paper strip detects conversion box, the detection box comprises two parts, and test paper strip box bottom A is independent or swing joint in test paper strip box lid B, test paper strip box bottom A both sides are equipped with the channel, test paper strip box lid B lid width and box bottom phase-match. The lateral flow chromatography test paper detection conversion box provides a tool for splicing a plurality of test paper strips, overcomes the defect of manual disassembly, has reasonable structural design, provides a connecting channel for the test paper by two strip grooves, stabilizes the connected test paper by a stop block at the top of the cover, is small, exquisite and portable, has simple process and low cost, can be repeatedly used, and can be discarded or recycled if special requirements exist.
Description
Technical Field
Analytical chemistry rapid inspection platform field
Background
The rapid detection test paper prepared based on the lateral flow chromatography technology, namely the lateral flow chromatography test paper, can be used for rapidly detecting biological macromolecules such as small molecules, proteins, nucleic acids and the like on site. The detection method is easy to operate, low in cost and visible in detection results, and has been widely applied in the fields of clinical diagnosis, environmental monitoring, food safety analysis and the like.
The lateral flow chromatography test paper consists of four components: the sample pad, the combination pad, the chromatographic membrane and the absorbent pad are overlapped on the supporting bottom plate as shown in figure 1 to form a simple lateral flow chromatography test strip. The sample pad is a treated fiber film or glass wool and is used for rapidly absorbing a sample to be detected, so that the sample can flow laterally towards the direction of the bonding pad by utilizing capillary action; the binding pad is a fibrous membrane or glass wool, is adsorbed with a marked bioactive material (such as a gold-labeled antibody), and can be combined with a detection target in a sample solution to be detected to form a macroscopic immune complex; the chromatographic membrane is mostly a Nitrocellulose (NC) membrane, which is a key material in the lateral flow analysis technology, provides a platform for the reaction between analytes, and is fixed with two or more different bioactive substances (such as antigens or antibodies), and a spray-printed "Test Line" (T Line) and a "Control Line" (C Line) for intercepting the labeled immune complex and visually displaying the detection result; the water absorption pad is a water absorption paper board and is used for absorbing the sample to be detected flowing through the chromatographic membrane so as to balance the pressure difference on two sides of the chromatographic membrane and promote more samples to be detected to flow laterally on the chromatographic membrane.
The existing structure refitting and splicing of the lateral flow chromatography test paper do not have corresponding auxiliary accessories or tools, experimental staff all rely on manual disassembly and assembly, certain potential safety hazards exist for personal safety of the experimental staff, technical requirements for the experimental staff are high, and experimental success rate is low.
Disclosure of Invention
In order to provide tool support for splicing and recombining the side-flow chromatography test paper structure, and to overcome the defects, the invention provides the side-flow chromatography test paper strip conversion detection box which can realize splicing and reutilization of the side-flow chromatography test paper strip structure.
The detection conversion box consists of a box bottom A and a box cover B, wherein the box bottom A is movably connected with the box cover B or is mutually independent, and the width of the box cover B is matched with that of the box bottom A; the detection box is characterized in that the box bottom A and/or the box cover B are/is provided with a channel, and/or the box bottom A is connected with the box cover B to form a channel, the detection box is provided with 2 channels in total, the channels are matched with the width of the test paper strip, and the 2 channels are positioned on the same horizontal line and are mutually butted.
The channel may be adapted to allow the test strip to slide in.
Preferably, both sides of the box bottom A and/or the box cover B are respectively provided with a left side runner baffle and a right side runner baffle. The height of the baffle plate is 1-3.5 mm, and a test strip which is firmly inserted.
Preferably, a window is arranged in the middle of the test strip box cover B, and the window is smaller than the width of the test strip. The design can facilitate operators to check and control the connection degree of the left test paper and the right test paper.
Preferably, the box bottom A is provided with an inclined plane, and the inclined plane is positioned on the box bottom A or the box cover B.
The inclined plane is 4-10 cm away from one side, the gradient of the inclined plane is 2-85 degrees, and the length of the inclined plane is 1-30 mm. The inclined plane can realize that the test strip sliding in from one channel can reach the designated position, so that the test strip sliding in from the other channel can be smoothly connected with the stop test strip by 4-10 mm by being supported by the inclined plane.
Preferably, two opposite rail tops are arranged on the inclined plane, are positioned at the box bottom A or the box cover B and are not in the same structure with the inclined plane, and one rail top is parallel to the inclined plane.
The gradient of the track top is 2-14 degrees, one top is 4-4.12 mm long, and the other top is 2-2.06 mm long. The track top can control the bending degree of the slide-in test strip to smoothly connect the two test strips.
Preferably, the box bottom A and the box cover B are provided with connecting shafts, and the connecting shafts are used for movably sleeving the box bottom A and the box cover B. The movable sleeving method comprises the steps of using a string and an iron wire.
Preferably, the butt joint of the two channels is respectively provided with a baffle and a stop block, and the positions and the sizes of the baffle and the stop block correspond to each other. For allowing the inserted test strip to reach a designated location within the channel.
Preferably, the box bottom A and the box cover B are provided with matched connecting columns, and the connecting columns are used for movably connecting the box bottom A and the box cover B.
Advantageous effects
The assembled type lateral flow chromatography test paper detection conversion box changes the mode that the traditional test paper strip only carries out chromatography once, disassembles, splices and reorganizes the components of the test paper strip, breaks the sequence of a conventional sample pad and a conventional binding pad, and is arranged in different independent units. The device which has high matching performance, simplified operation and easy implementation is provided for the small molecule rapid detection method of the paper platform, and is beneficial to the implementation of the method. The detection method of pre-enrichment is matched (a method for disassembling the loaded test strip, re-assembling part of the structure, and performing chromatography by using buffer solution so as to achieve the effect of pre-enrichment), so that the detection is performed rapidly and effectively, the naked eye detection limit of 1-3 orders of magnitude is reduced, and the application prospect is wide.
The lateral flow chromatography test paper detection conversion box has reasonable structural design, two grooves provide connecting channels for test paper, the stop block at the top of the cover stabilizes the connected test paper, and the lateral flow chromatography test paper detection conversion box is small, light, simple in process, low in cost, reusable, and capable of being discarded or recycled if special requirements exist. The lateral flow chromatography test paper detection conversion box has simple and easy use method, can be flexibly adjusted and detached, provides a standard spliced test paper platform, and has low technical requirements for operators.
Drawings
FIG. 1 is a schematic diagram of a prior art lateral flow chromatography test strip
FIG. 2 is a diagram showing the structure of a test strip test conversion box for lateral flow chromatography in example 1
Wherein A is the bottom of the test paper strip box; 1 is a left side channel; 2 is a right side channel; 3 is an inclined plane;
wherein B is test paper a bar box cover; 4 is a track roof; 5 is a window; 6 is a left side runner baffle and 7 is a right side runner baffle.
FIG. 3 is a block diagram of a test strip detection switch box for a flow-through chromatography test of example 2
Wherein, the test paper strip box bottom A; a is a box bottom channel; c is a box bottom baffle; j is a front connecting column of the box bottom; k is a rear connecting column at the bottom of the box; d and i are box bottom connecting shafts;
wherein B is a test strip box cover; e is a box cover a channel; g is a box cover baffle; f is a box cover stop block; h is a visual window; l is a front connecting column of the box cover; m is a rear connecting column of the box cover; i is a box cover connecting shaft;
b is the gap between the connections.
FIG. 4 is a lateral flow chromatography test of example 3 paper strip detection conversion box use diagram
Detailed Description
The following description of the embodiments of the present invention will be made apparent and fully in view of the accompanying drawings, in which some, but not all embodiments of the invention are shown. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of this protection.
Example 1
Referring to fig. 2, the present invention provides a test paper detection conversion box, which includes a test paper box bottom a and a test paper box cover B (long x wide x high=28 x 9 x 5 mm) 3 ) The left side and the right side of the bottom A of the test paper strip box are provided with a left side channel 1 and a right side channelAnd 2, the channel is matched with the width of the test strip, and the width of the box cover B of the test strip box is matched with the box bottom.
The box bottom A is designed with an inclined plane 3 with the gradient of 35 degrees at the position 10cm away from the No. 1 port, and the inclined plane is 10mm long. Slide baffles 6 and 7 are arranged on two sides of the test paper box cover B, the heights of the slide baffles are 2mm, and a window 5 smaller than the width of the test paper is arranged in the middle. The test strip box cover B is provided with two opposite track tops 4 with the gradient of 8 degrees, one of which is 4mm long and the other of which is 2mm long.
Example 2
The test strip I is provided with a sample pad, a chromatographic membrane and an absorption pad (without a combination pad) in sequence in a linear arrangement mode, and then a sample solution is loaded on the sample pad to lead a target detection object to be enriched in a detection area (T area) of the chromatographic membrane in advance; the II test strip is provided with a combination pad and a sample pad in sequence in a linear arrangement. And (3) sliding the II test strip from the channel 1 of the detection conversion box in the front face upwards, and then sliding the turned bottom face of the I test strip from the channel 2 of the detection conversion box upwards after the first chromatography is finished, so as to be connected with the II test strip, and continuously uploading the sample solution or the buffer solution on the sample pad of the II test strip.
Example 3
Referring to fig. 3, a test paper detection conversion box for flow measurement chromatography according to the present invention is composed of two parts, wherein part a is a bottom of the test paper box, and part B is a box cover (A, B, length x width x height = 21 x 15 x 2 x 5 mm) of the conversion box with identical dimensions 3 ). a is a bottom channel of the box, and the width of the bottom channel is 3mm, so that the test strip can slide in from the side. e is a groove of the box cover, and the width range is 3mm, so that the test strip can slide in from the side. And b is a gap between the connection of the AB two parts, the height range is 2mm, and the degree of connection of the two test strips can be flexibly adjusted. c is a test strip baffle plate at the bottom of the box, and the height range is 5mm, so that the inserted test strip reaches the appointed position in the channel. g is a baffle, the height range is 3mm, and the test strip can be firmly inserted. f is the upper stop block of the box cover, the length range is 2mm, the width range is 2.5mm, and the height range is 15mm, so that the test paper strip can be stabilized, the gap between the box cover and the box bottom can be filled, and the two test paper strips are connected with proper tightness. h is a visual window, and the width rangeThe condition that two test strips are connected can be clearly seen for 2mm. j. k is two connecting columns on the box bottom, the length range is 2mm, the width range is 2mm, the height is 3mm, and the movable connecting effect is achieved on the box cover and the box bottom. l and m are two connecting columns on the box cover, and the length, width and height are set to be the same as j and k. d and i are AB two parts connecting shaft, the diameter of the aperture of the connecting shaft is 2mm, and the AB two parts can be tightly and movably connected together through iron wires.
Example 4
A sample pad, a chromatographic membrane and an absorption pad (without a binding pad) are sequentially arranged in a linear arrangement by referring to a test strip I shown in FIG. 4, and then a sample solution is loaded on the sample pad to pre-enrich a target detection object in a detection area (T area) of the chromatographic membrane; the II test strip is provided with a combination pad and a sample pad in sequence in a linear arrangement. And (3) sliding the test strip II from the channel a of the detection conversion box in the front face upwards, then inserting the test strip I from the gap b of the detection conversion box after the first chromatography is finished, and connecting the test strip II with the test strip II, wherein the test strip II can continuously upload a sample solution or a buffer solution on a sample pad of the test strip II.
The lateral flow chromatography test paper detection conversion box provided in the above embodiments 1-4 has reasonable structural design, two grooves provide the connecting channels for the test paper, the stop block at the top of the cover stabilizes the connecting test paper, the window on the cover provides a visual environment for an operator, the operator can observe the splicing condition of the test paper in real time conveniently, the lateral flow chromatography test paper detection conversion box is small and light, the process is simple, the cost is low, the lateral flow chromatography test paper detection conversion box can be repeatedly used, and if special requirements exist, the lateral flow chromatography test paper can be discarded or recycled. The detection method is matched with a pre-enrichment detection method (a method for disassembling a test strip which is already loaded, recombining partial structures, and performing chromatography by using a buffer solution so as to achieve the pre-enrichment effect), so that the detection is performed rapidly and effectively, the naked eye detection limit of 1-3 orders of magnitude is reduced, and the application prospect is wide.
Claims (6)
1. The detection conversion box is characterized by comprising a box bottom (A) and a box cover (B), wherein the box bottom (A) is movably connected with the box cover (B) or is independent of the box cover (B), and the width of the box cover (B) is matched with that of the box bottom (A); the lateral flow chromatography test strip detection conversion box is provided with 2 channels, the widths of the channels and the test strips are matched, and the 2 channels are positioned on the same horizontal line and are in butt joint with each other;
the box bottom (A) or the box cover (B) is provided with an inclined plane; the inclined plane is 4-10 cm away from one side, the gradient of the inclined plane is 2-85 degrees, and the length of the inclined plane is 1-30 mm; two opposite rail tops are arranged on the inclined plane, are positioned at the box bottom (A) or the box cover (B) and are not in the same structure with the inclined plane, wherein one rail top is parallel to the inclined plane; the gradient of the track top is 2-14 degrees, one top is 4-4.12 mm long, and the other top is 2-2.06 mm long.
2. The lateral flow chromatography test strip detection conversion box according to claim 1, wherein a left side channel baffle and a right side channel baffle are respectively arranged on two sides of the box bottom (A) and/or the box cover (B).
3. The lateral flow chromatography test strip detection conversion box according to claim 1, wherein a window is arranged in the middle of the box cover (B), and the window is smaller than the width of the test strip.
4. The lateral flow chromatography test strip detection conversion box according to claim 1, wherein the box bottom (A) and the box cover (B) are provided with connecting shafts, and the connecting shafts are used for movably sleeving the two.
5. The lateral flow chromatography test strip detection conversion box according to claim 1, wherein the butt joint parts of the 2 channels are respectively provided with a baffle and a stop block, and the positions and the sizes of the baffle and the stop block correspond to each other.
6. The lateral flow chromatography test strip detection conversion box according to claim 1, wherein the box bottom (A) and the box cover (B) are provided with matched connecting columns, and the connecting columns are used for movably connecting the box bottom (A) and the box cover (B).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910496846.1A CN110082518B (en) | 2019-06-10 | 2019-06-10 | Lateral flow chromatography test strip detects conversion box |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910496846.1A CN110082518B (en) | 2019-06-10 | 2019-06-10 | Lateral flow chromatography test strip detects conversion box |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110082518A CN110082518A (en) | 2019-08-02 |
| CN110082518B true CN110082518B (en) | 2024-04-09 |
Family
ID=67423845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910496846.1A Active CN110082518B (en) | 2019-06-10 | 2019-06-10 | Lateral flow chromatography test strip detects conversion box |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110082518B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113252656B (en) * | 2021-06-17 | 2022-04-12 | 中国农业科学院农业质量标准与检测技术研究所 | Detection device for lateral flow chromatography, carrier tray and sample containing plate |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN206020272U (en) * | 2016-09-07 | 2017-03-15 | 深圳市康百得生物科技有限公司 | A kind of chromatography detection card |
| WO2018068582A1 (en) * | 2016-10-10 | 2018-04-19 | 广州瑞博奥生物科技有限公司 | Immunochromatography detection apparatus |
| CN207352024U (en) * | 2017-10-19 | 2018-05-11 | 石河子大学 | The detection box of quick detection cloth disease IgM and IgG |
| CN108663513A (en) * | 2018-04-20 | 2018-10-16 | 江南大学 | A method of reducing Sidestream chromatography test paper detection limit |
| CN208721676U (en) * | 2017-12-22 | 2019-04-09 | 杭州博拓生物科技股份有限公司 | The detection device of analyte in a kind of detection fluid sample |
| CN211426511U (en) * | 2019-06-10 | 2020-09-04 | 江南大学 | Lateral flow chromatography test paper strip detection conversion box |
-
2019
- 2019-06-10 CN CN201910496846.1A patent/CN110082518B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN206020272U (en) * | 2016-09-07 | 2017-03-15 | 深圳市康百得生物科技有限公司 | A kind of chromatography detection card |
| WO2018068582A1 (en) * | 2016-10-10 | 2018-04-19 | 广州瑞博奥生物科技有限公司 | Immunochromatography detection apparatus |
| CN207352024U (en) * | 2017-10-19 | 2018-05-11 | 石河子大学 | The detection box of quick detection cloth disease IgM and IgG |
| CN208721676U (en) * | 2017-12-22 | 2019-04-09 | 杭州博拓生物科技股份有限公司 | The detection device of analyte in a kind of detection fluid sample |
| CN108663513A (en) * | 2018-04-20 | 2018-10-16 | 江南大学 | A method of reducing Sidestream chromatography test paper detection limit |
| CN211426511U (en) * | 2019-06-10 | 2020-09-04 | 江南大学 | Lateral flow chromatography test paper strip detection conversion box |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110082518A (en) | 2019-08-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Domann et al. | Separation‐based glycoprofiling approaches using fluorescent labels | |
| Lee et al. | Picomolar analysis of proteins using electrophoretically mediated microanalysis and capillary electrophoresis with laser-induced fluorescence detection | |
| Krylov et al. | Instrumentation for chemical cytometry | |
| US5587062A (en) | Sample collecting apparatus by gel electrophoresis | |
| Gong et al. | On-line sample preconcentration using field-amplified stacking injection in microchip capillary electrophoresis | |
| Mao et al. | Capillary isoelectric focusing with whole column imaging detection for analysis of proteins and peptides | |
| Zhuang et al. | Electrophoretic analysis of N-glycans on microfluidic devices | |
| JP2021099359A5 (en) | ||
| US20070199821A1 (en) | Automated two-dimensional gel electrophoresis | |
| US20050133370A1 (en) | Analyte injection system | |
| CA2493322A1 (en) | Accessible assay device and method of use | |
| CN110082518B (en) | Lateral flow chromatography test strip detects conversion box | |
| US20140227772A1 (en) | Integrated modular unit including an analyte concentrator-microreactor device connected to a cartridge-cassette | |
| CN1740779A (en) | Analyzing system and analysing method based on integrated micro-flow control chip | |
| BR9603273A (en) | Multilayer reagent test strip for measuring analyte concentration in a biological fluid sample applied to the strip and process for measuring analyte concentration in a biological fluid sample | |
| CN211426511U (en) | Lateral flow chromatography test paper strip detection conversion box | |
| JPH03115850A (en) | Gel splitting electrophoretic apparatus and trace splitting electrophoretic apparatus | |
| Li et al. | Isoelectric focusing array with immobilized pH gradient and dynamic scanning imaging for diabetes diagnosis | |
| EP1006356A2 (en) | Capillary electrophoretic apparatus | |
| US20080227209A1 (en) | Methods, Kits And Devices For Analysis Of Lipoprotein(a) | |
| CN208795705U (en) | A kind of thin-layer chromatography Raman spectrum combined instrument | |
| CN104075916A (en) | High-efficiency and high-sensitivity biomacromolecule trans-membrane and staining system and device | |
| CN205450006U (en) | A full-automatic routine urine analyzer | |
| Sahlin | Two-dimensional capillary electrophoresis using tangentially connected capillaries | |
| Shimura et al. | Isoelectric focusing in a microfluidically defined electrophoresis channel |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |