CN206995285U - The cardiac ventricular septal defect closer of developed degradable - Google Patents
The cardiac ventricular septal defect closer of developed degradable Download PDFInfo
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- CN206995285U CN206995285U CN201620008208.2U CN201620008208U CN206995285U CN 206995285 U CN206995285 U CN 206995285U CN 201620008208 U CN201620008208 U CN 201620008208U CN 206995285 U CN206995285 U CN 206995285U
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Abstract
The utility model discloses a kind of cardiac ventricular septal defect closer of developed degradable, it includes the one first plate-like net, a tubular reticulum and one second plate-like net being sequentially connected, and the first plate-like net, the tubular reticulum and the second plate-like net are formed in one；The connector for being used for that wire side to close up is provided with the interior wire side center of the second plate-like net；The connector for being used for that wire side to close up is provided with the outer wire side center of the first plate-like net, the connector is formed by the dictyosome hot melt shaping at the outer wire side center of the first plate-like net；The first plate-like net, tubular reticulum, the material of the second plate-like net and connector are the degradation material that can develop, and the height of the tubular reticulum is 3.5 9.5mm.The utility model not only enables the degradable silk to develop of composition plate-like net be securely attached together, and connector is securely attached together with forming the degradable silk to develop of plate-like net, it is not easy to comes off.
Description
Technical field
It the utility model is related to a kind of cardiac ventricular septal defect closer of developed degradable.
Background technology
Ventricular septal defect is one kind in common congenital heart disease.Human heart is the (left side being made up of four chambers
Atrium, left ventricle, atrium dextrum and right ventricle), there should be a complete interventricular septum between left ventricle and right ventricle, if
There is opening just referred to as ventricular septal defect on cardiac septum.Ventricular septal defect is mainly formed in the growth and development process of fetus
In, developed due to have impact on heart by certain factor, so as to form ventricular septal defect.Come for the patient of ventricular septal defect
Say, blood would generally flow into right ventricle by left ventricle through ventricular septal defect, increase the blood volume of right ventricle.Ventricular septal defect
Long-term existence pulmonary arterial pressure can be caused to increase, congestive heart failure, palpitaition, asthma, the disease such as weak, recurrent pulmonary infection
Disease.The thickness of the cardiac septum apex in face from top to bottom is by thin thickening, and the relatively thin part of cardiac septum is between heart chamber
Diaphragm portion, the thicker part of cardiac septum is cardiac septum pars muscularis.
Ventricular septal heart defect is common congenital heart disease, and traditional therapeutic modality is surgical operation.Surgical operation
Treatment method, the shortcomings that patient need to surgically open chest, and its is maximum is：(1) extracorporal circulatory system is needed in art, operation may
Cause complication and cause death；(2) surgery operating wound is big, postoperative to leave scar；(3) surgery cost is expensive.
From the 1980s with intubation intervention diagnosis and the development and raising for the treatment of technology, China is gradually introducing minimally invasive
Interventional technique treat congenital heart disease, developed rapidly by the method for Minimally Interventional Therapy ventricular septal defect, very into
It is ripe.Compared to traditional surgery, Minimally Interventional Therapy is a kind for the treatment of of modern high technology minimal invasive, by femoral venous puncture,
Arteriovenous track is established using guide wire under the guiding of medical imaging device, delivery conduit is then placed in room along guide wire
Septal defect position, finally by ventricular septal defect in pushed in delivery conduit at ventricular septal defect implement closure control
Treat.Such Minimally Interventional Therapy have do not operate on, wound is small, few intercurrent disease, recover fast, effect is good, indication scope is wide and
The relatively low advantage of surgery cost.
Though have by the treatment method of minimally invasive intervention operation implantation ventricular septal defect many of the above relative to tradition
The advantage of surgical operation.But due to the material master used in the main body rack of the ventricular septal defect of present Clinical practice
To be nitinol alloy wire, because this metalloid material can not degrade, be chronically implanted can and tissue be inflamed, blood coagulation etc. it is anti-
Should, even a certain degree of damage, therefore the defects of certain be present, it is possible to risk used below be present in it：(1) NiTi
Alloy is nondegradable metal alloy compositions, although its biocompatibility is proved, the long term of long-term Permanent implantation
Risk can not be still perfectly controlled；(2) due to Nitinol Permanent implantation and non-degradable, heart is forever retained to human body
The influence for the heart that security, fixed-size heart occluder are constantly grown to children still lacks long-term follow-up money
Material, it may influence the growing of the patient's heart of undeveloped mature；(3) complication such as nickel precipitation, nickel allergy does not have yet
Clear and definite scientific appraisal.
On heart occluder surface by complete endothelialization, after heart defect is repaired by body autologous tissue, heart closure
Necessity that device is not retained in vivo completely.Therefore, preferable heart occluder should repair to provide one for heart itself
Temporary bridge, degraded after completing historic mission by body, defect is repaired completely by autologous tissue, so as to avoid metal from retaining body
The long term complication and potential safety hazard inside brought.
The supporting construction for the degradable plugging device introduced in United States Patent (USP) US08480709B2 is formed by pipe cutting, is blocked
The tie point of two cards of device is similar with dual welding spots, makes projection at two card centers, can increase plugging device surface local thrombus
The risk of formation, it is unfavorable for the endothelialization process on plugging device surface, meanwhile, the release of plugging device is made during implant surgery
Length is longer, easy impair cardiac tissue, and the plugging device compliance and recovery that are fabricated to by this method are poor, needs
It is assisted to reply original shape by locking device.
Utility model content
The technical problems to be solved in the utility model is deposited to solve the ventricular septal defect of existing Clinical practice
The long term risk the problem of, and prior art is overcome the defects of compliance and poor recovery of degradable plugging device to be present,
A kind of cardiac ventricular septal defect closer of developed degradable is provided.
The utility model is that solve above-mentioned technical problem by following technical proposals：
A kind of cardiac ventricular septal defect closer of developed degradable, its feature are that it includes one be sequentially connected
First plate-like net, a tubular reticulum and one second plate-like net, the first plate-like net and the second plate-like net are double-deck guard,
The both ends of the tubular reticulum are connected to the interior wire side of the first plate-like net and the outer wire side of the second plate-like net, described
First plate-like net, the tubular reticulum and the second plate-like net are formed in one；At the interior wire side center of the second plate-like net
Provided with the connector for wire side to be closed up, the connector is heated by the dictyosome at the interior wire side center of the second plate-like net
Shaping forms, and the connector is provided with internal thread in the relative end of the wire side with connecting；The outer wire side of the first plate-like net
At center be provided be used for by wire side close up connector, the connector by the first plate-like net outer wire side center net
Body heat is melt into shape and formed；The first plate-like net, tubular reticulum, the material of the second plate-like net and connector are dropping of can developing
Material is solved, the height of the tubular reticulum is 3.5-9.5mm.
It is preferred that the connector is tubulose, the height of the connector is 1.5-2.0mm.So cause the second plate-like
There is enough intensity at the interior wire side closing in of net.If the height of connector is too small, the thread turns inside connector is very few, meeting
Cause and be connected with induction system insecure and the risk that plugging device comes off be present., whereas if the height of connector is excessive, can increase
The risk for adding plugging device surface local thrombus to be formed, the side plugging device superficial cell climbing with connector can be caused slower,
Extend the endothelialization process on plugging device surface.Meanwhile make the release length of plugging device longer during implant surgery, easily
Impair cardiac tissue.
It is preferred that the external diameter of the connector is 2.5-3.2mm.So cause have at the interior wire side closing in of the second plate-like net
Enough intensity.In addition, if connector outside dimension is too small, easily cause to be connected with connector during connecting member forming
Degraded silk occur fracture or bonding strength decline., whereas if connector outside dimension is excessive, plugging device can be reduced and be applicable
The size range of delivery sheath, and it is unfavorable for push of the plugging device in delivery sheath.
It is recessed it is preferred that the Intranet of the second plate-like net faces at the connector.The wire side of depression can to seal
Stifled device using when stably and firmly can be plugged at ventricular septal heart defect.
It is preferred that the external diameter of the first plate-like net is bigger or isometrical than the external diameter of the second plate-like net.First plate-like net
Positioned at left ventricle, the second plate-like net is located at right ventricle, and for the patient of ventricular septal defect, blood would generally be passed through by left ventricle
Ventricular septal defect flows into right ventricle, and this structure makes the first plate-like net positioned at left ventricle have larger support force, can supported
The impact of anti-blood flow, be advantageous to plugging device and be firmly clamped at ventricular septal defect, so can be effectively by cardiac septum
Blocked at defect.Meanwhile can avoid impeding surrounding tissue, reduce the infringement to surrounding tissue.
It is preferred that the length of the tubular reticulum is 3.5-5.5mm.This length and the thickness of membranous part of interventri cular septum defective tissue
It is corresponding, to make plugging device preferably be fixed at defect without damaging tissue, and realize effectively closure.
It is preferred that the length of the tubular reticulum is 6.0-9.5mm.This length and the thickness of muscular part of interventricular septum defective tissue
It is corresponding, to make plugging device preferably be fixed at defect without damaging tissue, and realize effectively closure.
It is preferred that one first described plate-like net, a tubular reticulum, the material of one second plate-like net and the connector are
The high molecular degradable silk that can develop.The described high molecular degradable silk to develop is high by developing material and biodegradable
Molecular material is spinned and formed again after being well mixed by the method for blending, the ratio of Biodegradable polymer material and developing material
Example scope is 70-98wt%：30-2wt%, Biodegradable polymer material is PLA, polyglycolic acid, polycaprolactone, poly-
One kind in Lanthanum Isopropoxide, poly butyric ester, condensing model, polyphosphate, polyurethane, makrolon or at least two
Copolymer, developing material are Iohexol, iotalamic acid, amidotrizoic acid, sodium iodide, Ioversol, cardiografin, Iopromide, iodine gram
Husky alcohol, barium sulfate, basic bismuth carbonate, iron powder or hydroxyapatite.These materials have good biocompatibility, in human body
It can fully absorb, avoid long-term influence of the implantation foreign matter on human body.This plugging device simply provides one for cardiac repair
Temporary bridge, degraded after completing historic mission by body, defect is repaired completely by autologous tissue, so as to avoid metal from retaining body
The long term complication and potential safety hazard inside brought.
A kind of webmaster weaving method, including pin is inserted in the pinhole of mould rod, the degradable silk that can develop is penetrated
Sewing needle pin hole, knot and closely connect.Starting point is closely knotted with the degradable silk that can develop, during braiding uplink with it is descending
The intersection point of line aligns with centre mark point, with the trend of specification silk.Woven webmaster carries out thermal finalization together with mould rod.It is fixed
After type is good, pin is pulled out, removes webmaster.This weaving method makes the grid of webmaster more uniform, easily operated, reduces making
Cost.
A kind of preparation method of connector, making step include：
Step 1, webmaster is closed up；
Step 2, webmaster is put into mould；
Step 3, finishing dictyosome；
The degradable silk that step 4, heating can develop；
Step 5, shaping connector profile and internal whorl；
Step 6, remove dictyosome；
It is preferred that in step 1, the closing in end margin length of webmaster is first adjusted, edge is alignd, use can develop degradable
Silk closes up.
It is preferred that in step 2, the webmaster that will close up, through the sleeve pipe in mould.
It is preferred that in step 3, stay a part to be used for making connector in original assembling length, remove the unnecessary of webmaster
Length.
It is preferred that in step 4, temperature control device is opened, adjusts temperature, against developing at connector above mould
Degradable silk continuous heating, wherein, adjustment temperature is continuous heating time 5- 30 DEG C -90 DEG C on high molecular polymer fusing point
15 seconds, in heating process, over-heating can cause the other parts of dictyosome to heat together, so as to cause dictyosome destructurized,
And the material molecule amount of connector part is greatly reduced, material premature breakdown can be caused.Conversely, heating is insufficient, can cause
Degradable silk at connector, which can not be heated fully, to be integrated, and can not form complete connector female thread structure, the company of causing
Fitting and the bonding strength of induction system are inadequate.Therefore, it is necessary to which suitable acid extraction could be completed to heat.
It is preferred that in step 5, after continuous heating, the degradable silk to develop of connector part is fused together, and is moved
Temperature control device is opened, the sliding block being then shut off in mould, and by the slot above the thread head insertion mould of mould, kept for one section
Time.
It is preferred that in step 6, after cooling, the thread head rotation of mould is removed into mould, and sliding block is slowly removed,
Dictyosome is removed into mould.
The preparation method of this connector is easily operated, can obtain the connector of dimensionally stable, and reduces plugging device
On using material species, the degradable silk of composition plate-like net is securely attached to together, and make connector and composition
The degradable silk of plate-like net can be securely attached to together, it is not easy to be come off.
A kind of dictyosome method for shaping, including the dictyosome with connector is packed into dictyosome shaper, and consolidated with fixture
It is fixed, it is carried out thermal finalization together, after stereotyped, dictyosome be removed from the molds.Degradable membrane is packed into dictyosome with suture,
And it is a solid connector to carry out closing up at closing in end.This dictyosome method for shaping is easily operated, the occluder size of making
Stable, the plugging device made by this kind of method has larger support force and preferable recovery of shape, meets operation technique
It is required that make operation more effective, safer.
Positive effect of the present utility model is：
The utility model plugging device is knitted to form by the high molecular degradable silk that can develop, and its biodegradation period is 6
The moon to 2 years, can fully absorb in human body, avoid long-term influence of the implantation foreign matter on human body.This high score to develop
The degradable silk of son be by developing material and Biodegradable polymer material by the method for blending it is well mixed after spin again and
Into, make plugging device radiography, image definition under x-ray equipment in interventional procedure, be easy to it is minimally invasive intervention operation operation, carry
The accuracy and success rate of height operation.Used in the utility model can developing material be also degradable or human body is absorbable
Material, it is nontoxic to human body, there is good biocompatibility.The choked flow film of plugging device is biological degradable membrane, its biology
Degradation cycle is 6 months to 2 years, and degradation in vivo after it treats mission is completed in human body and is disappeared, noresidue foreign matter.Second
Dictyosome at the interior wire side center of plate-like net is connector by high temperature sweat soldering, specifically, by the second plate-like net
Interior wire side center at dictyosome heat at high temperature, and heat-fused portion dictyosome is shaped into connector with mould, so makes group
The degradable silk to develop of discoid net is not easy to scatter, and can be securely attached together；Simultaneously so that connector and composition
The degradable silk to develop of plate-like net can be securely attached together, it is not easy to be come off.The wire side for being not installed with connector is adopted
The structure to be closed up with connector, the support force and recovery of plugging device can be increased.In addition, this plugging device also has manufacturing cost
The advantages of low.
Brief description of the drawings
Fig. 1 is the plugging device dimensional structure diagram of the utility model preferred embodiment.
Fig. 2 is the plugging device connector schematic diagram of the utility model preferred embodiment.
Fig. 3 is the A direction views in Fig. 1.
Fig. 4 is the plugging device connector schematic diagram of the utility model preferred embodiment.
Fig. 5 is the mould rod structural representation of the utility model preferred embodiment.
Fig. 6 is that the braiding of the webmaster of the utility model preferred embodiment threads schematic diagram.
Fig. 7 is the closing in end expanded schematic diagram of the webmaster of the utility model preferred embodiment.
Embodiment
Name preferred embodiment, and become apparent from intactly illustrating the utility model with reference to accompanying drawing.
As shown in Figure 1, Figure 2, Figure 3, Figure 4, a kind of cardiac ventricular septal defect closer of developed degradable, it include according to
The first plate-like net 10, the plate-like net 20 of tubular reticulum 30 and second of secondary connection, the first plate-like net 10 and the second plate-like net 20 are double
Layer guard, the both ends of tubular reticulum 30 are connected to the outer wire side of the plate-like net 20 of interior wire side 11 and second of the first plate-like net 10
22, the first plate-like net 10, the plate-like net 20 of tubular reticulum 30 and second are formed in one；At the center of interior wire side 21 of second plate-like net 20
Provided with the connector 40 that wire side closes up, connected between the interior wire side 21 and connector 40 of the second plate-like net 20 for sweat soldering；
Connector 40 is formed by the dictyosome hot melt shaping at the center of interior wire side 21 of the second plate-like net 20, and connector 40 is in the net with connecting
The relative end in face is provided with internal thread；The connector for being used for that wire side to close up is provided with the center of outer wire side 12 of first plate-like net 10
13, connector 13 is formed by the dictyosome hot melt shaping at the center of outer wire side 12 of the first plate-like net 10；First plate-like net 10, tubulose
The material of net 30, the second plate-like net 20 and connector 40 is the degradation material that can develop.
Dictyosome of the plugging device of the present utility model at the interior wire side center of the second plate-like net 20 passes through high temperature sweat soldering
For connector, specifically, heated at high temperature by the dictyosome at the interior wire side center to the second plate-like net 20, and use mould
Heat-fused portion dictyosome is shaped into connector 40, so makes the degradable silk to develop of composition plate-like net be not easy to scatter, energy
It is securely attached together；Simultaneously so that connector 40 can be firmly attached with forming the degradable silk to develop of plate-like net
Together, it is not easy to come off.
Connector 40 is tubulose, is highly 1.5-2.0mm, external diameter 2.5-3.2mm.The interior wire side 21 of second plate-like net 20
It is recessed at towards connector 40.The external diameter of first plate-like net 10 is bigger or isometrical than the external diameter of the second plate-like net 20；The length of tubular reticulum 30
Spend for 3.5-9.5mm.It is corresponding with the thickness of membranous part of interventri cular septum defective tissue when length is 3.5-5.5mm；Length is 6.0-
It is corresponding with the thickness of muscular part of interventricular septum defective tissue during 9.5mm.Connector 40 is tubulose, and connector 40 is in the net with connecting
The relative end in face 21 is provided with internal thread.
The material of first plate-like net 10, the plate-like net 20 of tubular reticulum 30 and second and connector 40 is the macromolecule that can develop
Degradable silk.The described high molecular degradable silk to develop is passed through altogether by developing material and Biodegradable polymer material
Spin and form again after mixed method is well mixed, the proportion of Biodegradable polymer material and developing material is 70-
98wt%：30-2wt%, Biodegradable polymer material is PLA, polyglycolic acid, polycaprolactone, poly- to dioxocyclohex
One kind or at least two copolymer in ketone, poly butyric ester, condensing model, polyphosphate, polyurethane, makrolon, show
Shadow material is Iohexol, iotalamic acid, amidotrizoic acid, sodium iodide, Ioversol, cardiografin, Iopromide, Iodixanol, sulfuric acid
Barium, basic bismuth carbonate, iron powder or hydroxyapatite.In plugging device can filling polylactic acid film so as to play a part of stop blood flow.
The utility model connector is formed by degradable silk hot melt, and needs to meet use condition, not only structure
It excessive can not cause to hinder push of the plugging device in delivery sheath, also to avoid because not caused enough the connector of bonding strength
Pull.
Table 1, connector size, anti-pulling-out force and the push test table in delivery sheath
Found in test, ensure that connector will not be pulled in use when anti-pulling-out force reaches 15N.Pass through upper table
It can be seen that the size of connector directly influences whether plugging device normally can be applied among operation in 1.Connector
Inappropriate size design connector can be caused to be pulled, or cannot be introduced into delivery sheath and pushed, these all can
Product is caused not use.
The mesh-covered tray of this plugging device first is continuous netted face, is closed up between its netting twine using connector, the structure is favourable
Improved in the reply of stopper shapes and support force.Plugging device of the present utility model is at the interior wire side center of the second plate-like net
Dictyosome is connector by high temperature sweat soldering, specifically, is existed by the dictyosome at the interior wire side center to the second plate-like net
Heated under high temperature, and heat-fused portion dictyosome be shaped into connector with mould, so make composition plate-like net develop drop
Solution silk is not easy to scatter, and can be securely attached together；Simultaneously so that connector and developing for composition plate-like net are degradable
Silk can be securely attached together, it is not easy to be come off.
The making of the utility model plugging device is mainly by webmaster shaping, connector making, dictyosome sizing and polylactic acid membrane
Sew several steps.
When webmaster weaves, by the pinhole 51 of pin insertion such as Fig. 5 mould rod 5, the degradable silk that can develop is penetrated
Sewing needle pin hole, knot and closely connect.The threading rule of braiding is as shown in fig. 6, including connector manufacturing terminal D, closing in end B
(turning into connector 13 after shaping) and starting point C.Closely knotted with the degradable silk that can develop at starting point C, during braiding uplink with
The intersection point of downlink aligns with centre mark point, with the trend of specification silk.Woven webmaster carries out heat together with mould rod to be determined
Type.After stereotyped, pin is pulled out, removes webmaster.
Connector making step includes：
1st, webmaster is closed up；
2nd, webmaster is put into mould；
3rd, dictyosome is repaired；
4th, the degradable silk that can develop is heated；
5th, connector profile and internal whorl are molded；
6th, dictyosome is removed；
Wherein, in step 1, the closing in end margin length of webmaster is first adjusted, edge is alignd, the degradable silk that use can develop
Close up, specific closing in mode is as shown in fig. 7, including pin mark 61 and entry point 62 is gone out, and the order of threading is according in Fig. 7
Go out pin mark 61 and entry point 62 is closed up.In step 2, the webmaster that will have been closed up, through the sleeve pipe in mould.Step 3
In, stay a part to be used for making connector in original assembling length, remove the additional length of webmaster.In step 4, temperature control is opened
Device, temperature is adjusted, against the degradable silk continuous heating to develop at connector above mould.In step 5, continuing
After heating, the degradable silk to develop of connector part is fused together, and removes temperature control device, the cunning being then shut off in mould
Block, and by the slot above the thread head insertion mould of mould, kept for a period of time.In step 6, after cooling, by mould
Thread head rotation remove mould, and sliding block is slowly removed, dictyosome is removed into mould.
In addition, in step 4, adjustment temperature is continuous heating time 5-15 30 DEG C -90 DEG C on high molecular polymer fusing point
Second.Shown in table 2- tables 4 specific as follows, in heating process, over-heating can cause the other parts of dictyosome to heat together, so as to lead
Cause dictyosome destructurized, and greatly reduce the material molecule amount of connector part, so as to which material premature breakdown can be caused.Instead
It, heating is insufficient, and the degradable silk at connector can be caused fully to heat and be integrated, can not be formed and completely connected
Fitting female thread structure, cause the bonding strength of connector and induction system inadequate.Therefore, it is necessary to suitable heating-up temperature and when
Between could complete hot melt.
Table 2,70wt%L- lactide/glycolides (82/18) and developed degradable material made of 30wt% Iodixanols
Material hot melt test table
Table 3,85wt% PPDOs and developed degradable material hot melt made of 15wt% Iohexols are tested
Table
| Heat time s | Heating-up temperature DEG C | Connector heats situation | Other parts heat situation | |
| 1 | 2 | 190 | Do not heat fully | Do not heat |
| 2 | 15 | 120 | Do not heat fully | Do not heat |
| 3 | 5 | 190 | Fully hot melt | Do not heat |
| 4 | 5 | 130 | Fully hot melt | Do not heat |
| 5 | 15 | 190 | Fully hot melt | Do not heat |
| 6 | 15 | 130 | Fully hot melt | Do not heat |
| 7 | 5 | 200 | Fully hot melt | Part holt melt |
| 8 | 20 | 130 | Fully hot melt | Part holt melt |
Developed degradable material heat made of table 4,98wt%L- lactides/caprolactone (70/30) and 2wt% barium sulfate
Molten test table
Dictyosome sizing includes mould and dictyosome heat treatment shaping on dictyosome.On dictyosome during mould, the foregoing net with connector
Body is packed into dictyosome shaper, and is fixed with fixture, it is carried out thermal finalization together, after stereotyped, by dictyosome from mould
Take out.Polylactic acid membrane is packed into dictyosome with suture, and it is a connector at closing in end close up.
In description of the present utility model, it is to be understood that term " on ", " under ", "front", "rear", "left", "right",
The orientation or position relationship of the instruction such as " vertical ", " level ", " top ", " bottom ", " interior ", " outer " be based on orientation shown in the drawings or
Position relationship, it is for only for ease of description the utility model and simplifies description, rather than indicates or imply signified device or member
Part must have specific orientation, with specific azimuth configuration and operation, therefore it is not intended that to limitation of the present utility model.
Although the foregoing describing specific embodiment of the present utility model, it will be appreciated by those of skill in the art that
This is merely illustrative of, and the scope of protection of the utility model is defined by the appended claims.Those skilled in the art
On the premise of without departing substantially from principle of the present utility model and essence, various changes or modifications can be made to these embodiments,
But these changes and modification each fall within the scope of protection of the utility model.
Claims (6)
1. a kind of cardiac ventricular septal defect closer of developed degradable, it is characterised in that it includes one be sequentially connected
One plate-like net, a tubular reticulum and one second plate-like net, the first plate-like net and the second plate-like net are double-deck guard, institute
The both ends for stating tubular reticulum are connected to the interior wire side of the first plate-like net and the outer wire side of the second plate-like net, and described
One plate-like net, the tubular reticulum and the second plate-like net are formed in one；Set at the interior wire side center of the second plate-like net
Have a connector for wire side to be closed up, the connector by the second plate-like net interior wire side center dictyosome hot melt into
Shape forms, and the connector is provided with internal thread in the relative end of the wire side with connecting；In the outer wire side of the first plate-like net
At the heart be provided be used for by wire side close up connector, the connector by the first plate-like net outer wire side center dictyosome
Hot melt shaping forms；The first plate-like net, tubular reticulum, the material of the second plate-like net and connector be can develop it is degradable
Material, the height of the tubular reticulum is 3.5-9.5mm, and the connector is tubulose, and the height of the connector is 1.5-
2.0mm, the Intranet of the second plate-like net faces to be recessed at the connector.
2. the cardiac ventricular septal defect closer of developed degradable as claimed in claim 1, it is characterised in that the connection
The external diameter of part is 2.5-3.2mm.
3. the cardiac ventricular septal defect closer of developed degradable as claimed in claim 1, it is characterised in that described first
The external diameter of plate-like net is bigger or isometrical than the external diameter of the second plate-like net.
4. the cardiac ventricular septal defect closer of developed degradable as claimed in claim 1, it is characterised in that the tubulose
The length of net is 3.5-5.5mm.
5. the cardiac ventricular septal defect closer of developed degradable as claimed in claim 1, it is characterised in that the tubulose
The length of net is 6.0-9.5mm.
6. the cardiac ventricular septal defect closer of developed degradable as claimed in claim 1, it is characterised in that described first
Plate-like net, the tubular reticulum, the material of the second plate-like net and the connector are the high molecular degradable silk that can develop.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020093926A1 (en) * | 2018-11-08 | 2020-05-14 | 先健科技(深圳)有限公司 | Occlusion device |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020093926A1 (en) * | 2018-11-08 | 2020-05-14 | 先健科技(深圳)有限公司 | Occlusion device |
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Address after: 15th Building, 388 Yindu Road, Xuhui District, Shanghai, 200231 Patentee after: Shanghai Jinkui Medical Devices Co., Ltd. Address before: Room 102, D Workshop, 1618 Yishan Road, Minhang District, Shanghai, 201103 Patentee before: Shanghai Jinkui Medical Implements Co., Ltd. |