CN206906405U - Test reaction device and chip-detecting apparatus - Google Patents

Abstract

The utility model provides a kind of test reaction device and chip-detecting apparatus, test reaction device includes lid, temperature-constant plate and heater, temperature-constant plate is provided with liquid tank on the end face towards the lid, reaction chamber is formed between lid and liquid tank, heater includes multiple heating plates for abutting against temperature-constant plate bottom surface, bearing of trend arrangement of multiple heating plates along temperature-constant plate.Chip-detecting apparatus passes through main transport mechanism, clean and change liquid mechanism and test reaction device, realize test chip automation movement, and have using test reaction device insulation, the function such as moisturizing, allow transmission mechanism to pass through test reaction device by budget speed and preset time, and filling test fluid can be realized to test chip by clean and change liquid mechanism and draw test fluid.Multi-angle servicing fluids, imbibition and aeration cleaning can be realized using clean and change liquid mechanism simultaneously, then realizes that biochip efficiently and accurately detects.

Description

Test reaction device and chip-detecting apparatus

Technical field

It the utility model is related to chip detection field, more particularly to a kind of test reaction device and chip-detecting apparatus.

Background technology

Biochip technology is by microphotography, according to the intermolecular principle specifically to interact, by life section Discontinuous analysis process integration is in the miniature biochemical analysis system on silicon or glass-chip surface in field, with reality Now to accurate, quick, large information capacity the detection of cell, protein, gene and other biological components.According to what is solidified on chip The difference of biomaterial, biochip can be divided into genetic chip, protein-chip, more carbohydrate chips and neuron chip.

When handling biochip, inspector is needed by a series of operation：Thing to be detected is filled first, is then filled miscellaneous Liquid is handed over, subsequent temperature is reacted within preset temperature, then needs the reagent of series reaction to be reacted again, be finally Clean surface then can image instrument by CCD and carry out observation analysis by way of centrifuge or air blowing, it is seen then that handle It is multiple that the equipment that period involves includes multiple devices, the processes such as heat-preserving equipment, manual sample injector, centrifugation apparatus, cleaning equipment, air pressure gun Miscellaneous degree is high, manual operation efficiency is low, program is cumbersome, human error then easily occurs, detection is failed.

Utility model content

First purpose of the present utility model is to provide a kind of test reaction device for realizing Automated condtrol.

Second purpose of the present utility model is to provide a kind of chip-detecting apparatus for realizing automation reaction treatment.

In order to realize the first purpose of the present utility model, the utility model provides a kind of test reaction device, and its feature exists In：Including lid, temperature-constant plate and heater, lid is covered in the top of temperature-constant plate, and temperature-constant plate is on the end face towards lid Liquid tank is provided with, forms reaction chamber between lid and liquid tank, heater includes multiple temperature-constant plate bottom surfaces that abut against Heating plate, bearing of trend arrangement of multiple heating plates along temperature-constant plate.

Further scheme is that lid is provided with multiple grooves being arranged side by side on the end face towards temperature-constant plate, more Individual groove is arranged along the bearing of trend of temperature-constant plate.

Further scheme is that liquid tank is connected by multiple conduits and formed.

Further scheme is that test reaction device also includes water inlet and discharge outlet, water inlet and discharge outlet difference It is arranged on two ends of liquid tank.

Further scheme is that the distance between bottom land of discharge outlet and liquid tank is preset height.

Further scheme is that the both sides on the bearing of trend of temperature-constant plate are provided with chute, and chute, which is used to install, to be transmitted Band component.

In order to realize the second purpose of the present utility model, the utility model provides a kind of chip-detecting apparatus, and its feature exists In, including

Transport mechanism, transport mechanism are used to transport test chip,

Clean and change liquid mechanism, clean and change liquid mechanism are used for towards the test chip filling in transport mechanism or draw test Liquid；

Test reaction device, test reaction device is using the test reaction device of any one of such scheme, transport mechanism Through reaction chamber.

Further scheme is that transport mechanism includes multiple transfer tape assembles；Multiple transfer tape assembles are in be arranged side by side, Chip is provided with transfer tape assemble and places position, transfer tape assemble passes through reaction chamber.

Further scheme is that clean and change liquid mechanism includes fluid injection component and imbibition component, and clean and change liquid mechanism is set On the end of temperature-constant plate；

Fluid injection component includes the first conduit, and the first conduit is arranged on the top of transport mechanism, and fluid injection component is used for by the One conduit fills test fluid towards the test chip in transport mechanism；

Imbibition component includes the second conduit, and the second conduit is arranged on the top of transport mechanism, and imbibition component is used for by the Two conduits draw test fluid towards the test chip in transport mechanism.

The beneficial effects of the utility model are, by main transport mechanism, clean and change liquid mechanism and test reaction device, Realize test chip automation movement, and have using test reaction device insulation, the function such as moisturizing so that transmission mechanism Test reaction device can be passed through by budget speed and preset time, and can be by clean and change liquid mechanism to test chip Realize filling test fluid and draw test fluid.Simultaneously multi-angle servicing fluids, imbibition and air blowing can be realized using clean and change liquid mechanism Cleaning, then realize that biochip efficiently and accurately detects.

Brief description of the drawings

Fig. 1 is the structure chart of the utility model apparatus for testing chip embodiment.

Fig. 2 is structure chart of the utility model apparatus for testing chip embodiment under another visual angle.

Fig. 3 is structure chart of the utility model apparatus for testing chip embodiment after lid is opened.

Fig. 4 is structure chart of the utility model apparatus for testing chip embodiment after lid is opened under another visual angle.

Fig. 5 is the Structure explosion diagram of the utility model apparatus for testing chip embodiment.

Fig. 6 is the enlarged drawing at A in Fig. 4.

Fig. 7 is sectional view of the utility model apparatus for testing chip embodiment at temperature-constant plate.

Fig. 8 is the enlarged drawing at B in Fig. 7.

Fig. 9 is the structure chart of transfer assembly in the utility model apparatus for testing chip embodiment.

Figure 10 is structure chart of the transfer assembly under another visual angle in the utility model apparatus for testing chip embodiment.

Figure 11 is the structure chart of the second clean and change liquid mechanism in the utility model apparatus for testing chip embodiment.

Figure 12 is the structure chart of the 3rd clean and change liquid mechanism in the utility model apparatus for testing chip embodiment.

Figure 13 is knot of the 3rd clean and change liquid mechanism under another visual angle in the utility model apparatus for testing chip embodiment Composition.

Figure 14 is the 3rd clean and change liquid mechanism sectional view in the utility model apparatus for testing chip embodiment.

Figure 15 is the system block diagram of the utility model apparatus for testing chip embodiment.

Figure 16 is the fundamental diagram of the utility model apparatus for testing chip embodiment.

Figure 17 is the structure chart of the 4th clean and change liquid mechanism in the utility model apparatus for testing chip embodiment.

Below in conjunction with drawings and Examples, the utility model is described in further detail.

Embodiment

Referring to figs. 1 to Fig. 4, test chip device includes the lid 12 of shell 11 and mutual lid, is provided with shell 11 Accommodating chamber, the accommodating chamber is used to accommodate the devices such as transport mechanism, clean and change liquid mechanism and test reaction device, and realizes automation Operating plus imbibition or reactions steps.Specifically, multiple test fluids are provided with the outer wall of shell 11 and place position, the placement position is used In placing test fluid storage container 13, chip outlet 111,12 L-shaped setting of lid, lid are provided with the left side wall of shell 11 12 middle part is made using light transmissive material so that user can be supervised with permeation parts lid to the situation of accommodating chamber Control, and form operation breach in the front of shell 11 and conveniently internal unit is operated.

Multigroup pump 14 is provided with the internal perisporium of accommodating chamber, and multiple test fluids are similarly provided with accommodating chamber and are deposited Storage container 13, pump 14 are used to the test fluid of test fluid storage container 13 being filled into test chip 10 by clean and change liquid mechanism On, or, pump 14, which is used to draw the test fluid in test chip 10, to be discharged into test fluid storage container 13.Certain test fluid Storage container 13 can both place untapped test fluid, and for depositing discarded test fluid.

Reference picture 5 and Fig. 6, transmission mechanism include transfer tape assemble 21, transfer tape assemble 221, transfer tape assemble 231 and passed Band component 241 is sent, transfer tape assemble 21, transfer tape assemble 221, transfer tape assemble 231 and transfer tape assemble 241 are in abreast to set Put, transfer tape assemble 21 is located at outside shell 11, and transfer tape assemble 221, transfer tape assemble 231 and transfer tape assemble 241 are located at In accommodating chamber.Transfer tape assemble 21 includes the flat board 211 of strip extension and the conveyer belt 212 positioned at the both sides of flat board 211, conveyer belt 212 slightly above flat board 211, transfer tape assembles 21 constitute the feeding area of apparatus for testing chip, and multiple test chips 10 can be horizontal Ground is placed on flat board 211, and drive conveyer belt 212 under the driving of the built-in motor of transfer tape assemble 21, and test chip 10 is passed It is sent to end.

Reference picture 7 and Fig. 8, three test reaction being arranged side by side devices, three test reactions are additionally provided with accommodating chamber The structure of device is roughly the same and use principle is identical, therefore is carried out exemplified by close to the test reaction device of transfer tape assemble 21 detailed Describe in detail bright.

Test reaction device includes lid 222, temperature-constant plate 223 and heater, towards lid 222 on temperature-constant plate 223 End face on be provided with the liquid tanks of multiple connections, liquid tank is interconnected, including three horizontal strokes extended along its length The vertical liquid tank extended to liquid tank and width, lid 222 are covered in the top of liquid tank, lid 222 and liquid tank Between form reaction chamber, reaction chamber is respectively arranged with opening on the bearing of trend of transfer tape assemble 221.Heater bag Include three heating plates 224 for abutting against the bottom surface of temperature-constant plate 223, bearing of trend uniform cloth of three heating plates 224 along temperature-constant plate 223 Put.

Test reaction device is also provided with water inlet and discharge outlet 225 on the two of each temperature-constant plate ends, referring to Fig. 4, temperature-constant plate 223,233,243 are arranged side by side in accommodating chamber, with the temperature-constant plate 233 at middle part for example, discharge outlet 225 The distance between bottom land of liquid tank is preset height, prevents that the liquid level of liquid is too high, and liquid can discharge from discharge outlet 225 To outside liquid tank, water inlet is then arranged on the other end of discharge outlet 225, and it is generally used for filling water towards liquid tank.

Both sides on the bearing of trend of temperature-constant plate are provided with chute, and chute is used to install transfer tape assemble 221, conveyer belt group Part 221 includes slidable conveyer belt and the limited block on transmission belt, and limited block is spacing for being carried out to test chip 10, Chip is formed between the adjacent limited block of homonymy and places position, reference picture 5, apparatus for testing chip is always according to each transmission belt component Drive component is equipped with, the drive component includes motor 251, transmission belt 252, axis and two groups of roll wheel assemblies 253, roller group Part includes the roller that two ends coordinate, and motor 251 drives middle shaft rotation, two roll wheel assemblies 253 by transmission belt 252 Set up separately in two ends of axis, each roll wheel assembly 253 transmission band connection with transfer tape assemble 221 respectively, utilize axis Rotation synchronous drive two conveyer belts synchronously operated in chute, then realize the transport of test chip 10.

Lid 222 is towards being provided with multiple grooves 226 being arranged side by side, multiple grooves 226 on the end face of temperature-constant plate 223 Arrange that the bearing of trend of a groove 226 is perpendicular to the bearing of trend of temperature-constant plate 223, recessed along the bearing of trend of temperature-constant plate Groove 226 is set in tiny channel-shaped, by the setting of multiple grooves 226, can effectively increase end of the lid 222 towards temperature-constant plate The entire area in face, and can effectively suppress water droplet on cover plate and be formed, it ensure that experiment effect.

By test reaction device and the matching design of transport mechanism, using multiple separately controllable heating plates to reaction Chamber, temperature-constant plate and temperature-constant plate are heated, and cause the water thermally equivalent of the conduit of multiple connections, and also cause reaction chamber Interior thermally equivalent, and cover the INSULATION DESIGN of temperature-constant plate in lid, i.e. lid 222 covers temperature-constant plate 223, and lid 232 covers Temperature-constant plate 233, lid 242 cover temperature-constant plate 243, ensure that each reaction chamber realizes that different temperature accurately controls, and in fact The accurate temperature controller in the different length region in an existing reaction chamber.And except temperature control, water in temperature-constant plate can by It after heat, can accelerate to evaporate, humidity can be then provided for reaction chamber, while cover using more groove portions of lid, effectively increase The area of the bottom end face of body, the formation of water droplet can be effectively prevented, so as to prevent water droplet from being formed and dropped to from lid In test chip 10.

Coordinate the reaction chamber with certain tightness, the temperature and humidity of reaction chamber can be controlled well.Again Person, one or more temperature sensors and humidity sensor can be set on lid diverse location, pass through the temperature of sensor Obtain and humidity obtains, reaction chamber can be controlled in real time.In addition, reaction chamber has entrance at both ends and gone out Mouthful, the conveyer belt of transport mechanism drives test chip to pass through the reaction chamber, and then test chip can be located in reaction chamber Test reaction is carried out in preset temperature and default humidity.

Reference picture 9 and Figure 10, and Fig. 4 and Fig. 6 is combined, multiple transfer tape assembles are to be arranged side by side, and test chip needs Transfer tape assemble passes through three test reaction devices successively, therefore needs the transfer assembly by being connected between transfer tape assemble Shifted, therefore transfer device also includes transfer assembly 31, transfer assembly 32 and transfer assembly 33, transfer assembly in the present embodiment Structure and application principle all same, between transfer tape assemble 21 and transfer tape assemble 221 chip transmission be to pass through transfer group Part 31 is come what is shifted, and transfer assembly 32 is connected between transfer tape assemble 221 and transfer tape assemble 231, and transfer assembly 33 connects Between transfer tape assemble 231 and transfer tape assemble 241.

It is described in detail below with transfer assembly 31, transfer assembly 31 includes housing 311, motor 312, driving wheel 314th, driven pulley 319, timing belt 315, sliding block 318, main absolute position encoder 313 and from absolute position encoder 316, definitely Position coder 313 and individual pen absolute value encoder can be used from absolute position encoder 316, individual pen absolute value encoder can To be photoelectric encoder, magnetic encoder, resolving encoder, capacitive grating encoder.311 rectangular framework of housing sets and at middle part Be provided with accommodating chamber, be provided with slide rail 317 on the first side wall of accommodating chamber, slide rail 317 is set in groove, sliding block 318 from The slide rail 317 is passed through in accommodating chamber, sliding block 318 is arranged in slide rail 317 and can moved along slide rail 317.The He of motor 312 It is arranged on from absolute position encoder 316 on the outer wall of the second sidewall of accommodating chamber, driving wheel 314, driven pulley 319 and timing belt 315 are arranged in accommodating chamber, and driving wheel 314 is arranged on the output shaft of motor 312, main absolute position encoder 318 It is connected on the output shaft of motor, timing belt 315 is connected between driving wheel 314 and driven pulley 419, and sliding block 318 is set On timing belt 315, it is connected from absolute position encoder 316 by rotating shaft with driven pulley 319.And the diameter of driving wheel 314 with The diameter and the number of teeth of driven pulley 319 differ, and in the present embodiment, the diameter of driving wheel 314 is less than the diameter of driven pulley 319 Ground is set, and the number of teeth of driving wheel 314 is less than the number of teeth of driven pulley 319.Motor can use servomotor, stepper motor or DC brushless motor etc..

In order to accurately know the position of test chip 10 and sliding block 318, existing design generally by Multi-turn absolute value encoder coordinates motor accurately to control turned position.Transfer assembly 31 stirs test chip When, because the diameter of driving wheel is less than the diameter of driven pulley, therefore driving wheel 314 is obtained by main absolute position encoder 313 Rotational angle data, by obtaining the rotational angle data of driven pulley 319 from absolute position encoder 316, when there is step-out, By comparing the rotation data of driving wheel and driven pulley, and the relation ratio according to two diameters, and according to the pass between the number of teeth System, just can calculate the number of turns that driven pulley/driving wheel turns over, and calculate the position of current slide, and the present embodiment uses Scheme be by two absolute value encoders, different-diameter size, the driving wheel of poor, encoder the resolution ratio of the number of teeth and driven Wheel measures calculating, and its cost is low and the purpose and function of this case can be realized using general motor.

Then test chip 10 at transfer tape assemble 21 can be sent to transfer tape assemble exactly by sliding block 318 At 221, meanwhile, limited block is collinearly set, and has opening, sliding block 318 between two limited blocks on the width of temperature-constant plate Just by test chip 10 between the limited block that opening enters and is pushed on transmission belt.

On the end of transfer tape assemble 221, i.e., test chip, which enters on the position of transfer tape assemble 221, is provided with first Clean and change liquid mechanism, the first clean and change liquid mechanism includes fluid injection component 51 in the present embodiment, fluid injection component 51 include L-type support and Three conduits 511 being arranged on support, conduit 511 arrange that three conduits 511 are connected with pump 14 respectively in vertical direction, lead to Cross in the presence of pump 14, test fluid is filled into test chip 10.Test chip 10 is provided with three test positions 101, test Position is used to place testing liquid and test fluid, and test position 101 is in groove arrangement, and sets conduction hole on adjacent two side, Conduction hole 102 is located on length direction, and conduction hole 103 is located on width, in the present embodiment the curved groove of conduction hole Set.During practical application, test fluid is uniformly distributed in test position 101 during filling test fluid to allow, can pass through The initial filling position of the cooperation of transfer tape assemble 221 and pump 14, i.e. conduit 511 is located at the opposite side of conduction hole 102, Ran Houchuan Sending the mobile test chip 10 of band component 221, conduit 511 continues to fill test fluid, as test chip 10 moves, conduit 511 simultaneously Close to conduction hole 102, the then stopping of conduit 511 filling, then realize that conduit 511 is equably filled on test position 101 Test fluid.Then enter test reaction device under the drive of transfer tape assemble 221, carry out the stop or walking of preset time, Period, test fluid and prepare liquid were fully reacted also under default temperature and humidity state.

When test chip 10 is sent to the other end by transfer tape assemble 221, then by transfer assembly 32 by test chip On 10 transfer conveyor belt components 231, the second clean and change liquid mechanism is provided with the end for moving transfer tape assemble 231.Specific ginseng According to Figure 11, the second clean and change liquid mechanism 52 includes lifting assembly, fluid injection component, imbibition component and chip position, and chip position is used to put Put test chip 10.Lifting assembly includes motor, eccentric wheel, encoder 523, support 524, sliding block 528 and slide rail 526, Encoder is connected with motor, and motor driving eccentric wheel is circumferentially moved around the output shaft of motor, and sliding block is provided with waist Circular hole, eccentric wheel coordinate with waist round hole, and sliding block 528 is matched somebody with somebody with slide rail 526 and merges and can be slided along slide rail.

Imbibition component includes three conduits 529, and three conduits 529 are connected with pump, and it is used for from the side of test chip 10 Conduction hole draw test fluid, three conduits 529 are arranged on 527 on sliding block.Lifting assembly is connected with imbibition component and can driven Imbibition component relative to chip position lifting moving, realize when chip in place after to test chip progress imbibition processing.

Fluid injection component includes 521, three conduits 522 of support and three conduits 528, support 521 are fixedly provided in shell In 11, three conduits 522 are connected with pump, are set between conduit 522 and horizontal plane in filling inclination angle, inclination angle is at an acute angle sets for filling Put, the outlet of conduit 522 is located relative on the side of conduction hole 103, i.e. the entrance position of the outlet of conduit 522 and conduit 529 In on the both sides of test position 101.

Three conduits 528 are arranged on sliding block 528, and three conduits 528 are also to be moved, conduit with the movement of sliding block 528 528 position is accordingly set with the conduction hole 102 of test chip, and three conduits 528 are used to fill towards test chip 10 Test fluid

Second clean and change liquid mechanism 52 also includes the separate sheet 525 for being arranged on the both sides of conduit 529, and separate sheet 525 is in strip Shape is set, and separate sheet 525 is provided with inclined guide surface on the end close to support 521, and two separate sheets 525 are positioned at test The top of chip and to the position-limiting action on test chip 10 its vertical direction, its reason be conduit 528 when drawing test fluid, Suction may suck up test chip 10, therefore spacing, guarantee can be effectively carried out to test chip by separate sheet 525 Conduit 528 efficiently separates with test chip.

When second clean and change liquid mechanism 52 is operated, in the end of transfer tape assemble 231, test chip 10 is first When entering the chip position of clean and change liquid mechanism, test chip 10 is to be mounted with test fluid, and the second clean and change liquid mechanism 52 is being entered Row needs first to carry out cleaning step when changing second of test fluid.

Therefore the control method of the second clean and change liquid mechanism 52 includes：

Test fluid in test chip 10 is drawn by conduit 529；

Then, cleaning solution is filled by conduit 522, meanwhile, conduit 529 draws cleaning solution simultaneously, due to conduit 522 and leads Pipe 529 is on both sides, thus incline direction fill cleaning solution, and produce convection current on the test position of test chip, then have Effect improves cleaning force.

Then, conduit 522 stops filling cleaning solution, and conduit 529 draws cleaning solution clean；

Finally, second of test fluid is filled to test chip by conduit 527, during filling, test chip 10 is by conveyer belt Component 231 drives, and with the movement of test chip 10, conduit 527 fills.

As test chip by transfer tape assemble 231 drives test reaction device into temperature-constant plate 233, by it is default when Between, the reaction of temperature and humidity, test chip is sent to the other end, then again by transfer assembly 32, by test chip Transfer tape assemble 241 is transferred to from transfer tape assemble 231.The starting end of transfer tape assemble 241 is provided with the second cleaning to change Liquid mechanism 52, subsequent second clean and change liquid mechanism 52 perform above-mentioned control method to test chip, and second of test fluid is inhaled Take, and after cleaning, add the third test fluid.

Test chip is driven by transfer tape assemble 241 again, into the test reaction device of temperature-constant plate 243, by default Time, the reaction of temperature and humidity, test chip are sent to the other end, finally by the 3rd clean and change liquid mechanism 53.

Reference picture 12 to Figure 14, clean and change liquid mechanism 53 include lifting assembly, translation component, air blowing component, fluid injection component, Imbibition component and chip position, translation component include motor 531, support 532, eccentric wheel 539, sliding block 534 and slide rail 533, The output shaft of motor 531 is connected with eccentric wheel 539, and eccentric wheel 539 deviates the axis setting of output shaft, motor 531 driving eccentric wheels 539 are circumferentially moved around output shaft, and sliding block 534 is provided with waist round hole 538, eccentric wheel 539 and waist round hole 538 coordinate, and in arcuation setting, slide rail 534 and motor 531 be fixedly connected on support 532 support 532, and slide rail 533 is along water Square extend to the direct of travel of arrangement and test chip, sliding block 534 and slide rail 533 are with merging and can be slided along slide rail 533, air blowing Component is arranged on sliding block 534.

Air blowing component includes gas passage and the intake interface 536 of compressed air, and air pump interface 536 and gas passage connect Connect, gas passage is surrounded by pipeline block, and the gas passage of connection, the first end connection air inlet connecting of gas passage are opened up in pipeline block Mouthfuls 536, the second end of gas passage is provided with three gas outlets 536, gas outlet 536 towards conduit 545 entrance tilt and set Put, the gas outlet 536 of gas passage is used to blow to the chip surface on chip position.

Lifting assembly includes motor 523, support 524, eccentric wheel, sliding block 527 and slide rail 526, motor driving Eccentric wheel is circumferentially moved around the output shaft of motor, and sliding block is provided with waist round hole, and eccentric wheel coordinates with waist round hole, the He of slide rail 527 Motor 523 is fixedly installed on support 524 and is arranged in a vertical direction, and sliding block 544 and slide rail 543 are with merge can be along slide rail 543 are slided, and imbibition component is arranged on sliding block 544.

Imbibition component includes three conduits 545, the entrance of conduit 545 set towards chip position and be used to drawing test fluid and Cleaning solution, three conduits 545 simultaneously can accordingly move down into drawing for test chip 10 with the lifting moving of sliding block 544, its entrance In discharge orifice 102.The outlet of conduit 546 and the entrance of conduit 545 are arranged on the rear side of the bearing of trend of slide rail 533.

3rd clean and change liquid mechanism 53 is also including the separate sheet 537 for being arranged on the both sides of conduit 545, separate sheet and positioned at lifting Between component and chip position, separate sheet 537 is set in strip, and separate sheet 537 is provided with the end close to support 532 inclines Oblique guide surface, two separate sheets 537 are located at the top of test chip and to the spacing works on test chip 10 its vertical direction With, its reason be conduit 545 when drawing test fluid, suction may suck up test chip 10, therefore pass through separate sheet 537 Effectively test chip can be carried out spacing.

Fluid injection component includes three conduits 546, and three conduits 546 are arranged on the position between two separate sheets 537, and three Be set in parallel between individual conduit 546 and horizontal plane, certainly can also angle at an acute angle filling inclination angle set, three conduits 546 are used to fill cleaning solution towards chip position.

3rd clean and change liquid mechanism 53 changes liquid processing step in the last cleaning of processing test chip, its control method bag Include：

Test chip 10 is sent to the chip position of the 3rd clean and change liquid mechanism 53；

Lifting assembly drops to conduit 545 and cooperatively on position, conduit 545 is inhaled in the conduction hole of test chip 10 Take the test fluid in test chip 10；

Cleaning is then carried out, conduit 546 fills cleaning solution to test chip 10, while conduit 545 is also simultaneously Cleaning solution is drawn；

Then conduit 546 stops filling cleaning solution；

Finally, translate Component driver air blowing component to move towards the ground of conduit 545, air blowing component is towards chip while mobile Position is blown, meanwhile, conduit 545 draws the remaining cleaning solution in test chip 10, finally all inhales the cleaning solution on chip position Take clean.

Reference picture 15 and Figure 16, system block diagram and operation principles figure below in conjunction with apparatus for testing chip carry out test stream Journey explanation.Apparatus for testing chip is usually to be used cooperatively with external computer or embedded system or single-chip computer control system, And the processing module with processing operational capability can be integrated in apparatus for testing chip, the control in apparatus for testing chip Panel or upper computer software such as computer, flat board, mobile phone etc. can be configured to parameters, the parameter of setting include temperature, Time, humidity, transfer rate etc., additionally it is possible to pass through control panel or the operating state of apparatus for testing chip.

Apparatus for testing chip includes multiple driver elements, multiple motors and multiple encoders, such as above-mentioned embodiment institute The function to be realized and effect are mentioned to, multiple motors are respectively used to driving transfer tape assemble, transfer assembly, for adding The pump of note and the pump for absorption, a road motor of driver element band four and encoder, driver element are connected using Ethernet The driving plate connect, computer are connected by communication unit with each driver element, and connected mode can be connected by the way of series connection, Computer efficiently can be driven by coding to each motor, at the same using communication unit and humidity sensor, Temperature sensor and heater are controlled or the acquisition of information

When apparatus for testing chip is handled test chip to be tested, its control method includes：

First, thing to be detected is filled to test chip 10, is subsequently placed on the transfer tape assemble 21 of feeding area；

Then, test chip is sent to end, and by the transfer of transfer assembly 31, test chip is transferred to conveyer belt group On the end of part 221；

Then, fluid injection component 51 fills test fluid to test chip；

Then, transfer tape assemble 221 transfers to test chip, and by the test reaction device of temperature-constant plate 223, and Reacted 20 minutes to 120 minutes between 25 DEG C to 85 DEG C；

Then, subsequent test chip is sent to the other end, and is transferred to by transfer assembly 32 on transfer tape assemble 231 End on；

Then, the second clean and change liquid mechanism 52 performs above-mentioned processing step to test chip, including draws test fluid, leads to Over cleaning liquid cleans, and adds second of test fluid；

Then, transfer tape assemble 231 transfers to test chip, and by the test reaction device of temperature-constant plate 233, and Reacted 20 minutes to 120 minutes between 25 DEG C to 85 DEG C；

Then, subsequent test chip is sent to the other end, and is transferred to by transfer assembly 33 on transfer tape assemble 241 End on；

Then, above-mentioned processing step is being performed to test chip by the second clean and change liquid mechanism 52, including is drawing the Two test fluids, are cleaned by cleaning fluid, add the third test fluid；

Then, transfer tape assemble 241 transfers to test chip, and by the test reaction device of temperature-constant plate 243, and Reacted 20 minutes to 120 minutes between 25 DEG C to 85 DEG C；

Finally, above-mentioned processing step is performed to test chip by the 3rd clean and change liquid mechanism 53, including draws colour developing The test fluid of liquid the 3rd, is cleaned by cleaning fluid, and blowing is blotted, finally from the output of chip outlet 111.Detected by the chip of this case Device instead of artificial detection, and continual continuous detection can be achieved, and greatly improves detection efficiency, avoids the occurrence of detection mistake Lose.

It is further to note that this front side, rear side and left and right sides in embodiment is referred to along transfer tape assemble Direct of travel, the direction of advance of transfer tape assemble is front side, and the opposite side of front side is rear side, therefore for the second clean and change liquid The conduit 528 of mechanism 52 is to be located at front side, and conduit 522 is set positioned at rear side and the side that keeps left, and conduit 529 is to be located at right side； Conduit 545 and conduit 546 in second clean and change liquid mechanism 52 are to be located at rear side, and air blowing component is then to be located at front side.

Reference picture 17, the first clean and change liquid mechanism 51 in above-described embodiment and the second clean and change liquid mechanism 52 is replaceable makes With the 4th clean and change liquid mechanism 54, and the replaceable use test chip 20 of test chip 10 in above-described embodiment.

Specifically, the second clean and change liquid mechanism 54 includes lifting assembly, fluid injection component, imbibition component and chip position, chip Position is used to place test chip 20.Test chip 20 is provided with three test positions 201, and test position is used to place testing liquid and survey Test solution, test position 201 is in groove arrangement, and conduction hole 202,203 is set on relative two side, is drained in the present embodiment The curved groove in hole is set.

Lifting assembly includes motor, eccentric wheel, encoder 543, support 544, sliding block 548 and slide rail 546, encoder It is connected with motor, motor driving eccentric wheel is circumferentially moved around the output shaft of motor, and sliding block is provided with waist round hole, partially Heart wheel coordinates with waist round hole, and sliding block 548 is matched somebody with somebody with slide rail 546 and merges and can be slided along slide rail.

Imbibition component includes three conduits 549, and three conduits 549 are connected with pump, and it is used for the drainage from test chip 20 Draw test fluid in hole.Fluid injection component includes three conduits 541 being vertically arranged side by side and the conduit 542 set laterally side by side, and three Individual conduit 549 and three conduits 541 are connected with pump and fill test fluid, three conduits 549 and three towards test chip 20 respectively Individual conduit 541 is arranged on sliding block 548, also, the outlet of the entrance of conduit 549 and conduit 541 is used for towards the test core The middle part of piece, the outlet of conduit 542 is used for the sidepiece towards test chip, and conduit 542 inclined or parallel to horizontal plane Set.The position of conduit 549 is accordingly set with the conduction hole 202,203 of test chip, and lifting assembly is used to drive conduit 549 and the lifting moving of conduit 541, realize when chip in place after imbibition processing and filling processing are carried out to test chip.

When 4th clean and change liquid mechanism 54 is operated, the end in transfer tape assemble, test chip 20 is entering During the chip position of clean and change liquid mechanism, discriminably carry out drawing the first test fluid, the second test fluid of filling, draw the second test The 3rd test fluid of liquid and filling, then in test reaction device is entered.

Certain 3rd clean and change liquid mechanism 53 is also what can be changed, can be by the 4th clean and change liquid mechanism 54 with blowing Changed after component combination, its function and effect are identicals, are also that by the purpose of this utility model.

By main transport mechanism, clean and change liquid mechanism and test reaction device, test chip automatic moving is realized It is dynamic, and have using test reaction device insulation, the function such as moisturizing so that transmission mechanism can by budget speed and it is default when Between pass through test reaction device, and filling test fluid can be realized to test chip by clean and change liquid mechanism and is drawn and surveyed Test solution.Multi-angle servicing fluids, imbibition and aeration cleaning can be realized using clean and change liquid mechanism simultaneously, then realizes test chip height The accurate detection of effect.

Above-described embodiment is the preferred embodiment of this case, has a variety of changes, such as above-mentioned reality among practical application Apply in example and accurately controlled using motor, naturally also can using in general motor cooperation position sensor come Accurate transmission and positioning are realized, and for transfer assembly, can also general electricity in addition to the transfer assembly in such as above-mentioned embodiment Machine also can be achieved on the transfer between different transmission belt components to test chip with movable slider.

In addition, the walking path of the test chip of above-described embodiment is set with spiraling in wriggling, or set in square-wave-shaped Put, it is the volume that can efficiently reduce apparatus for testing chip, can naturally also be set along a straight line, and this is just no longer needed Want transfer assembly, it is only necessary to add clean and change liquid mechanism and test reaction device in position.

Claims (9)

1. test reaction device, it is characterised in that：Including lid, temperature-constant plate and heater, the lid is covered in the perseverance The top of warm plate, the temperature-constant plate are provided with liquid tank, the lid and the liquid tank on the end face towards the lid Between form reaction chamber, the heater includes multiple heating plates for abutting against the temperature-constant plate bottom surface, it is multiple described plus Bearing of trend arrangement of the backing along the temperature-constant plate.

2. test reaction device according to claim 1, it is characterised in that：

The lid is towards being provided with multiple grooves being arranged side by side, multiple equal edges of groove on the end face of the temperature-constant plate The bearing of trend arrangement of the temperature-constant plate.

3. test reaction device according to claim 1, it is characterised in that：

The liquid tank is connected by multiple conduits and formed.

4. test reaction device according to claim 1, it is characterised in that：

The test reaction device also includes water inlet and discharge outlet, and the water inlet and the discharge outlet are separately positioned on described On two ends of liquid tank.

5. test reaction device according to claim 4, it is characterised in that：

The distance between bottom land of the discharge outlet and the liquid tank is preset height.

6. the test reaction device according to any one of claim 1 to 5, it is characterised in that：

Both sides on the bearing of trend of the temperature-constant plate are provided with chute, and the chute is used to install transfer tape assemble.

7. chip-detecting apparatus, it is characterised in that including

Transport mechanism, the transport mechanism are used to transport test chip；

Clean and change liquid mechanism, the clean and change liquid mechanism are used for towards the test chip filling in the transport mechanism or draw survey Test solution；

Test reaction device, the test reaction device is using the test reaction dress described in any one of the claims 1 to 6 Put, the transport mechanism passes through the reaction chamber.

8. chip-detecting apparatus according to claim 7, it is characterised in that：

The transport mechanism includes multiple transfer tape assembles；

Multiple transfer tape assembles are provided with chip and place position, the conveyer belt in being arranged side by side on the transfer tape assemble Component passes through the reaction chamber.

9. chip-detecting apparatus according to claim 7, it is characterised in that：

The clean and change liquid mechanism includes fluid injection component and imbibition component, and the clean and change liquid mechanism is arranged on the temperature-constant plate On end；

The fluid injection component includes the first conduit, and first conduit is arranged on the top of the transport mechanism, the fluid injection group Part is used to fill test fluid towards the test chip in the transport mechanism by first conduit；

The imbibition component includes the second conduit, and second conduit is arranged on the top of the transport mechanism, the imbibition group Part is used to draw test fluid towards the test chip in the transport mechanism by second conduit.