CN205941575U - Fully -automatic biochemical analyzer - Google Patents
Fully -automatic biochemical analyzer Download PDFInfo
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- CN205941575U CN205941575U CN201620903596.0U CN201620903596U CN205941575U CN 205941575 U CN205941575 U CN 205941575U CN 201620903596 U CN201620903596 U CN 201620903596U CN 205941575 U CN205941575 U CN 205941575U
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Abstract
The utility model relates to a fully -automatic biochemical analyzer, this analysis appearance include reaction plate, detect the cup, detect cup belt cleaning device, more than one reagent group, shank -pin, sample needle, sample dish, reaction plate is used for placing the detection cup, it is used for wasing the detection cup to detect cup belt cleaning device, reagent group comprises reagent unit independent separately, and each reagent unit includes a reagent bottle, level sensor, reagent transfer device, first reagent needle, pipeline and a valve, and each reagent unit detects the cup and adds specific reagent to each, shank -pin is arranged in stirring the mixing and detects cup liquid, the sample cell sample that sample needle is arranged in absorbing the sample dish is to detecting the cup, the sample dish is used for placing the need checking sample pipe. The utility model discloses an independent reagent unit and agitating unit can effectively reduce the cross contamination who examines the different reagent of time measuring and reach the sample room within a definite time to improve and detect the accuracy, reduce water consumption and the waste liquid volume of wasing.
Description
Technical field
This utility model belongs to medical test detection technique field, particularly automatic clinical chemistry analyzer.
Background technology
Biochemistry analyzer is the testing equipment that medical institutions commonly use.The reagent distribution of current automatic clinical chemistry analyzer is all
Using shared reagent pin with share diluter composition system execution reagent distribution, that is, by reagent pin diluter driving
Lower reagent pin first draws a certain amount of reagent in reagent position, and then reagent pin moves to detection cup, is driven and will be tried by diluter
Reagent in agent pin is added in detection cup, additionally using shared mixing needle, the liquid in detection cup is stirred.
Different reagent are contacted respectively using shared reagent pin, mixing needle during existing automatic clinical chemistry analyzer detection, although
Before exchanging other reagent for, instrument needs to be carried out to inside and outside reagent pin and outside mixing needle, but is difficult to thoroughly prevent
Reagent pin, the residual of the different reagent of mixing needle contact, are therefore easily caused the cross-contamination between reagent.For eliminating instrument reagent
The reagent residual contamination of pin and mixing needle, especially reagent pin interior reagent remain, and generally require using substantial amounts of water and cleaning
Agent is carried out, and otherwise, remaining reagent will can produce severe contamination to the next reagent sucking.In addition biochemistry analyzer is in inspection
Also need to during survey the reactant in detection cup is mixed, could obtain good testing result, conventional agitating device
It is shared contact agitator, and because the risk necessarily leading to there is cross-contamination, existing full-automatic life are stirred in contact
Changing analyser is to reduce this kind of cross-contamination due to being formed between different reagent, sample, frequently with a large amount of water of consumption to reagent
Pin, mixing needle are carried out, but often clean not thoroughly because instrument speed limits, and also produce substantial amounts of waste water.Due to each
Detection cup random detection disparity items, therefore contacts different reagent and there is also the wind of different degrees of reagent residual in detection cup
Danger.
Utility model content
The purpose of this utility model is to provide a kind of automatic clinical chemistry analyzer.
The technical scheme realizing this utility model purpose is：A kind of automatic clinical chemistry analyzer, this analyser includes detecting
Cup, reaction tray, detection cup cleaning device, more than one reagent set, mixing needle, sample pin and specimen disc；
Described reaction tray is used for placing detection cup；Described detection cup cleaning device is used for cleaning detection cup；Described specimen disc
For placing testing sample pipe；The sample that described sample pin is used on pipette samples disk extremely detects in cup；
Each reagent set is made up of multiple reagent unit, and reagent unit is used for adding fixating reagent in corresponding detection cup；
Each reagent unit includes a reagent bottle, level sensor, reagent transfer device, the first reagent pin and connecting line,
Described reagent transfer device is used for reagent in driving the first reagent pin extraction reagent bottle, and, to detecting cup, level sensor is used for detecting
Reagent is had or not in connecting line；
Described mixing needle is used for liquid in stirring and evenly mixing detection cup.
Compared with prior art, remarkable advantage of the present utility model is：
(1) each reagent bottle one pipeline of independent connection in reagent set of the present utility model, and each reagent cartridge only shifts same
Kind of reagent, there is not the cross-contamination of different reagent in each reagent cartridge, reagent pin, therefore do not need at work to reagent pin and
Pipeline-cleaning；(2) this utility model passes through reactant in contactless air pressure mixing needle stirring detection cup, decreases mixing needle and leads
The cross-contamination causing；(3) this utility model takes each detection cup only cycle detection identical items, and not cross detection other item
Mesh, reduce instrument further to detect that the different reagent place of cup contact is formed is the cross-contamination that residual leads to；(4) this utility model is big
The big consumption reducing required abluent and water during instrument runs, also accordingly decreases the generation of waste liquid.
Brief description
Fig. 1 is the biochemical instruments structural representation using circular sample disk.
Fig. 2 is the biochemical instruments structural representation using rail mounted specimen holder.
In the full automatic biochemical apparatus that Fig. 3 designs for this utility model using an air pump realize simultaneously negative pressure waste discharge liquid and
The apparatus structure schematic diagram of barostat source of the gas is stirred in malleation air pressure supply.
Fig. 4 (a) produces liquid flowing in detection cup during impact air pressure on the left of liquid level for contactless air pressure mixing needle and shows
It is intended to, Fig. 4 (b) is liquid backflow schematic diagram after contactless air pressure mixing needle stopping pressure, Fig. 4 (c) is detection cup after stirring
Middle liquid level schematic diagram.
Fig. 5 is that this utility model reagent pin exports proper alignment structural representation.
Fig. 6 is shared reagent pin outlet mobile device of the present utility model and reagent pin outlet arrangements schematic diagram.
Fig. 7 is a reagent unit structural representation of the present utility model.
Fig. 8 is the biochemistry analyzer schematic diagram in this utility model one embodiment.
Specific embodiment
In conjunction with Fig. 1 and Fig. 6, a kind of automatic clinical chemistry analyzer of the present utility model, this analyser includes detecting cup 14, anti-
1, detection cup cleaning device 3, more than one reagent set, mixing needle, sample pin 6 and specimen disc 8 should be coiled；
Described reaction tray 1 is used for placing detection cup 14；Described detection cup cleaning device 3 is used for cleaning detection cup；Described sample
Product disk 8 is used for placing testing sample pipe；The sample that described sample pin 6 is used on pipette samples disk extremely detects in cup；
Each reagent set is made up of multiple reagent unit, and reagent unit is used for adding fixating reagent in corresponding detection cup；
Each reagent unit includes a reagent bottle 16,17, reagent transfer device 18 of level sensor, the first reagent pin N and company
Adapter road, described reagent transfer device 18 is used for driving reagent in the first reagent pin N extraction reagent bottle 16 extremely to detect cup 14, liquid level
Detector 17 is used for detecting and has or not reagent in connecting line；
Described mixing needle is used for liquid in stirring and evenly mixing detection cup.
Further, described each reagent set also includes a shared reagent pin mobile device, for by each for this group reagent pin
Outlet needs to move to above the detection cup specified according to detection.
Further, the reagent pin reagent exit of each reagent unit is neatly arranged on same straight line or camber line.
Further, described mixing needle is contactless air pressure mixing needle, the gas outlet of contactless air pressure mixing needle
Liquid level in direct detection cup；Described contactless air pressure mixing needle is connected with air pump and pressure-regulating device, described air pump
For blasting air and passing through contactless air pressure mixing needle ejection, described pressure-regulating device is used for adjusting contactless air pressure
Air-flow size, speed and time that mixing needle sprays.
Further, contactless air pressure mixing needle periphery is provided with heating and temperature regulating device, for contactless gas
In pressure mixing needle, gas is heated and thermostatic control, and air pressure mixing needle effluent air temp is controlled in the range of 20-45 DEG C.
Further, the reagent pipetting volume hole site in described reaction tray is provided with the lid of belt switch, in not reagent adding
Cover closing, when needing reagent adding, lid is opened.
Further, this analyser is additionally provided with reagent catcher, for collecting a small amount of reagent that reagent pin mouth is discharged.Cause
Deliver at reagent pin mouth for Confirmation reagent in firm access reagent for reagent pin, a small amount of reagent can have been discharged.
Further, described specimen disc is circular sample disk 8 or rail mounted specimen holder 7.
Further, this analyser also includes a reagent disc 22 and a second reagent pin 21, and described reagent disc 22 is used
In placing multiple reagent bottle, described second reagent pin 21 is to share reagent pin, for by reagent in reagent bottle each on reagent disc 22
It is transferred in detection cup.
Further, it is provided with the motor that baffle plate and controlling baffle plate rotate below described reagent pin.The gear when adding reagent
Plate is removed, and in not reagent adding, baffle plate crosspiece is under reagent pin, it is to avoid reagent instills in detection cup by mistake.
Further, described reagent transfer device 18 be syringe, quantitative peristaltic pump or quantitative shifting pump.
Further, described reagent position also sets up cold storage plant and temperature regulating device, controls temperature of reagent to be maintained at 2-15 DEG C
Scope.
Further, described reagent pin periphery is provided with device of rising again it is ensured that cold preservation reagent temperature when adding detection cup reaches
To more than 20 DEG C.
Further, level sensor detection mode is photosignal detection, current type or condenser type；Photosignal detects
Cleaning Principle be that to produce absorbance difference in pipeline obvious due to liquid and air.
Further, this analyser also includes a sample pre-dilution disk, for pre-dilution before sample detection.
Below taking two reagent set and two mixing needles as a example, the work of this utility model automatic clinical chemistry analyzer is described
Flow process：
Step 1：When the detection cup 14 of cleaning rotates to the first reagent adding position, a reagent unit in the first reagent set 2
Reagent one is added in this detection cup 14；
Step 2：Reaction tray 1 rotates a circle when stopping, and in step 1, former reagent adding position crossed by detection cup 14, is arranged in it
A detection cup afterwards stays in former reagent adding position, and a detection cup adds the identical or another reagent unit of the first reagent set backward
Enter reagent one；
Step 3：Reaction tray 1 often rotates a circle, the position of each detection cup edge reaction tray direction of rotation one cup of advance, when
Detection cup 14 reaches when adding sample position, and sample pin 6 adds quantitative sample in detection cup 14；
Step 4：Reaction tray 1 continues the position of each detection cup edge reaction tray direction of rotation one cup of advance that often rotates a circle
Put, when detecting that cup 14 reaches the first mixing position, the first mixing needle 5 is stirred to liquid in detection cup；
Step 5：Reaction tray 1 continues the position of each detection cup edge reaction tray direction of rotation one cup of advance that often rotates a circle
Put, when detecting cup 14 arrival plus the second reagent adding position, the second reagent set 4 adds reagent two；
Step 6：After adding reagent two, detection cup 14 moves to the second stirring position, and the second mixing needle 19 is in detection cup 14
Liquid is stirred；
Step 7：Reaction tray 1 drives the detection circulating rotation of cup, through one-time detection point in each rotary course, to detection
In cup, liquid carries out an optical signal detecting；
Step 8：Reaction tray 1 drive detection the circulating rotation of cup, reach cleaning position then respectively detection cup by detect cup clean
Device 3 cleans one by one；
Step 9：After completing cleaning, reaction tray 1 drives the detection circulating rotation of cup, and clean detection cup after cleaning revolves again
Go to the first reagent position.
Step 10：Detection cup after cleaning continues according to step 1-9, and circulation completes new pattern detection.
The utility model is described in further detail with reference to the accompanying drawings and examples.
Embodiment 1
In the present embodiment, reagent set is 2 groups, the respectively first reagent set 2 and the second reagent set 4, and mixing needle quantity is 2,
It is respectively the first mixing needle 5 and the second mixing needle 19, the first mixing needle 5 and the second mixing needle 19 are arranged on the different position of reaction tray 1
Put, for liquid in stirring and evenly mixing detection cup.
As shown in figures 1 to 6, in the first reagent set 2 reagent unit reagent pin reagent exit by share reagent
Pin mobile device moves to detection cup position, and the reagent transfer device of reagent unit draws reagent one, and drives quantitative reagent
It is added in a detection cup once the outlet of reagent pin, through multiple rotary, this detection cup 14 stops at sample bit to reaction tray afterwards
When putting, by sample needle 6, from circular sample disk 8, specimen cup is drawn in the testing sample above-mentioned detection cup 14 of addition, and detection cup 14 is through continuing
Continuous be rotationally advancing stirred to the first mixing position by the first mixing needle 5 after, detection cup 14 continues to be rotationally advancing to the second reagent set 4
During reagent adding position, the shared reagent pin mobile device of the second reagent set 4 moves a reagent pin outlet to this detection cup position
Put, the reagent transfer device in the second reagent set 4 drives quantitative reagent two to be added to above-mentioned detection cup 14, and detection cup 14 continues
Rotate after being stirred to the second mixing position by the second mixing needle 19, detection cup 14 gradually detects, through tool count in rotary course
Obtain testing result according to processing, detection is carried out to detection cup 14 by detection cup cleaning device 3 after terminating.
Embodiment 2
As shown in Fig. 2 the present embodiment is with the difference of embodiment 1, specimen cup is loaded on rail mounted specimen holder 7, rail
Road formula specimen holder 7 straight line single-way moving along its length, when through sample position, sample is got inspection to each sample by sample pin
Survey perform detection in cup 14.
Embodiment 3
In conjunction with Fig. 1 and Fig. 2, the present embodiment mesophytization analyser detects multiple difference biochemical projects simultaneously, but in reaction tray 1
Each detection cup only cycle detection identical items, and do not detect other projects.
In the present embodiment, reaction tray 1 designs and only loads 40 detection cups, 20 biochemical projects of cycle detection, detection project wheel
Turning number of times is 2.Respectively detect in cup in 1-20 respectively according to same sequence every time and add a kind of reagent in the first reagent set 2, afterwards
Add first sample, stirred with the first mixing needle 5 when reacting disc spins to the first stirring position, then according to same sequence is in 1-
Add a kind of reagent in the second reagent set 4 every time in 20 each detection cups, stirred with second when reacting disc spins to the second stirring position
Mix pin 19 to stir.Subsequently No. 21-40 detection cup adds a kind of reagent in the first reagent set 2 one by one according to the order of 1-20 before,
Add the second sample afterwards, stirred with the first mixing needle 5 when reacting disc spins to the first stirring position, then according to same sequence
Add a kind of reagent in the second reagent set 4 in No. 21-40 detection cup, stirred with second when reacting disc spins to the second stirring position
Mix pin 19 to stir.Each detection cup so can be realized and only detect identical items, and not detect disparity items.I.e. each detection cup only
Only accept identical reagent, and sample is different.
Embodiment 4
As shown in figure 3, the present embodiment passes through a vacuum pump 9, first pressure adjusts bottle 10 and second pressure adjusts bottle 11
Realize to the detection suction of cup cleaning device 3 waste liquid and the supply of air pressure mixing needle.
Its concrete structure and operate and be：Close the first valve V1 and the 3rd valve V3, vacuum pump 9 adjusts bottle to first pressure
10 pumpings form negative pressure；Now open the first valve V1, be negative pressure because first pressure is adjusted in bottle 10, the waste liquid in detection cup
It is inhaled into first pressure to adjust in bottle 10.While vacuum pump 9 work, air is blasted to second pressure regulation bottle 11 and make this bottle
The higher malleation of middle formation, opens the second valve V2, and gas passes through stirring barostat 5 and sprays, and impulse detection cup surface local is right
In detection cup, liquid realizes noncontact stirring.Can pass through to open the 4th valve V4 when second pressure regulation bottle 11 air pressure is too high,
Suitably release portion gas, keep second pressure to adjust bottle 11 air pressure moderate.
When the waste liquid that first pressure adjusts bottle 10 runs up to a certain amount of, vacuum pump 9 break-off, the first valve V1 and the
Three valve V3 open, first pressure adjust bottle 10 in accumulation waste liquid due to gravity can by be automatically drained out in bottle flow into waste collection
In device 12.
Embodiment 5
In conjunction with Fig. 4 (a), described contactless air pressure mixing needle 5 quantity is 1, is arranged on detection cup 14 ullage one
Side, the first barostat 5 forms impact air pressure in detection cup at liquid level 20 local, so that liquid level 20 local pressure in detection cup is more than
Other parts so that being declined by high-pressure section liquid level, localized liquid flows to area of low pressure, and relatively low pressure part liquid level due to
Other regions liquid extrudes and rises so that the liquid in cup flows.Fig. 4 (b) display stops pressure when air pressure mixing needle,
Former local is subject to high-pressure section pressure to reduce recovery normally, and liquid flows back, and Fig. 4 (c) is build-up of fluid normal position in detection cup
View.
Embodiment 6
As shown in Figure 5 and Figure 6, in the present embodiment, the reagent exit of multiple reagent pin N of each reagent unit is longitudinally neat arranges
Row, according to detection needs, drive belt to turn by sharing the cooperation of motor M1 and driven pulley M2 in reagent pin mobile device M
Dynamic, control reagent pin to move, the outlet of different reagent pins is moved on to detection cup position respectively, then corresponding reagent unit automatically will be corresponding
Quantitative reagent is added in detection cup, executes different item detections.
Embodiment 7
As shown in fig. 6, being provided with reagent catcher 13 in the present embodiment, for start when or the reagent that changes the outfit after by reagent
Transfer device 18 extracts a small amount of reagent and is drained into reagent catcher 13 it is ensured that reagent pin mouth delivered to by reagent when instrument works
Place, adds the reagent of detection cup enough each time.
Embodiment 8
As shown in fig. 7, in the present embodiment reagent unit include reagent bottle 16, level sensor 17, reagent transfer device 18,
5th valve V5, the 6th valve V6 and the first reagent pin N.Reagent transfer device 18 adopts syringe, when needing to distribute reagent
It is first turned on the 5th valve V5, closes the 6th valve V6, syringe piston is drop-down, in reagent bottle 16, reagent enters in syringe；
Close the 5th valve V5 afterwards, open the 6th valve V6, syringe piston pushes away, reagent passes through the first reagent pin N and flows out.
Embodiment 9
As shown in figure 8, the present embodiment with the difference of embodiment 1 is, analyser also includes reagent disc 22 and the second reagent pin
21；Reagent one is drawn by the first reagent set 2, reagent is second by the way of reagent disc 22 and the second reagent pin 21 structural grouping
Draw.
Claims (9)
1. a kind of automatic clinical chemistry analyzer is it is characterised in that this analyser includes detecting cup (14), reaction tray (1), detection cup
Cleaning device (3), more than one reagent set, mixing needle, sample pin (6) and specimen disc (8)；
Described reaction tray (1) is used for placing detection cup (14)；Described detection cup cleaning device (3) is used for cleaning detection cup；Described
Specimen disc (8) is used for placing testing sample pipe；The sample that described sample pin (6) is used on pipette samples disk (8) extremely detects in cup；
Each reagent set is made up of multiple reagent unit, and reagent unit is used for adding fixating reagent in corresponding detection cup；Each
Reagent unit includes a reagent bottle (16), level sensor (17), reagent transfer device (18), a first reagent pin (N)
And connecting line, described reagent transfer device (18) is for driving reagent in the first reagent pin (N) quantitation extraction reagent bottle (16)
To detection cup (14), level sensor (17) is used for detecting and has or not reagent in connecting line；
Described mixing needle is used for liquid in stirring and evenly mixing detection cup.
2. automatic clinical chemistry analyzer according to claim 1 is it is characterised in that described each reagent set also includes one altogether
With reagent pin mobile device, for the outlet of each for this reagent set reagent pin is needed to move to the detection cup specified according to detection
Side.
3. automatic clinical chemistry analyzer according to claim 2 is it is characterised in that each reagent pin outlet in each reagent set
Neatly it is arranged on same straight line or camber line.
4. automatic clinical chemistry analyzer according to claim 1 is it is characterised in that described mixing needle is contactless air pressure
Mixing needle, liquid level in gas outlet's direct detection cup of contactless air pressure mixing needle；Described contactless air pressure mixing needle is even
It is connected to air pump and pressure-regulating device, described air pump is used for blasting air and spraying by contactless air pressure mixing needle,
Described pressure-regulating device is used for adjusting air-flow size, speed and the time that contactless air pressure mixing needle sprays.
5. automatic clinical chemistry analyzer according to claim 4 is it is characterised in that contactless air pressure mixing needle periphery sets
It is equipped with heating and temperature regulating device, for being heated and thermostatic control to gas in contactless air pressure mixing needle.
6. automatic clinical chemistry analyzer according to claim 1 is it is characterised in that reagent pipetting volume hole in described reaction tray
Position is provided with the lid of belt switch, the cover closing in not reagent adding, and when needing reagent adding, lid is opened.
7. automatic clinical chemistry analyzer according to claim 1 is it is characterised in that described specimen disc is circular sample disk
Or rail mounted specimen holder (7) (8).
8. automatic clinical chemistry analyzer according to claim 1 is it is characterised in that this analyser also includes a reagent disc
(22) and one the second reagent pin (21), described reagent disc (22) is used for placing multiple reagent bottle, described second reagent pin (21)
For sharing reagent pin, for reagent in upper for reagent disc (22) each reagent bottle is transferred in detection cup.
9. automatic clinical chemistry analyzer according to claim 1 is it is characterised in that described reagent transfer device (18) is note
Emitter, quantitative peristaltic pump or quantitative shifting pump.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620903596.0U CN205941575U (en) | 2016-08-17 | 2016-08-17 | Fully -automatic biochemical analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620903596.0U CN205941575U (en) | 2016-08-17 | 2016-08-17 | Fully -automatic biochemical analyzer |
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| Publication Number | Publication Date |
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| CN205941575U true CN205941575U (en) | 2017-02-08 |
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ID=57947100
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| CN201620903596.0U Active CN205941575U (en) | 2016-08-17 | 2016-08-17 | Fully -automatic biochemical analyzer |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106199024A (en) * | 2016-08-17 | 2016-12-07 | 江苏英诺华医疗技术有限公司 | Automatic clinical chemistry analyzer and biochemical detection system |
| CN109876494A (en) * | 2019-04-10 | 2019-06-14 | 青岛励德仪器有限公司 | A kind of device and method for taking out upper layer solvent from layered solvent |
| CN112730785A (en) * | 2020-12-29 | 2021-04-30 | 清华大学合肥公共安全研究院 | A advance kind dish for water quality testing |
-
2016
- 2016-08-17 CN CN201620903596.0U patent/CN205941575U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106199024A (en) * | 2016-08-17 | 2016-12-07 | 江苏英诺华医疗技术有限公司 | Automatic clinical chemistry analyzer and biochemical detection system |
| CN109876494A (en) * | 2019-04-10 | 2019-06-14 | 青岛励德仪器有限公司 | A kind of device and method for taking out upper layer solvent from layered solvent |
| CN112730785A (en) * | 2020-12-29 | 2021-04-30 | 清华大学合肥公共安全研究院 | A advance kind dish for water quality testing |
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