CN205808807U - A kind of multichannel slide glass specimen incubating device with heating function - Google Patents
A kind of multichannel slide glass specimen incubating device with heating function Download PDFInfo
- Publication number
- CN205808807U CN205808807U CN201620216820.9U CN201620216820U CN205808807U CN 205808807 U CN205808807 U CN 205808807U CN 201620216820 U CN201620216820 U CN 201620216820U CN 205808807 U CN205808807 U CN 205808807U
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- slide glass
- heating
- discharge outlet
- glass specimen
- specimen
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- Investigating Or Analysing Biological Materials (AREA)
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Abstract
This utility model discloses a kind of multichannel slide glass specimen incubating device with heating function, mainly includes the parts such as slide glass, cover plate, bay groove, heater canister, spike, heating plate, electrothermal tube, cover board support, spring leaf, electric magnet, upper discharge outlet, lower discharge outlet.This utility model have employed slide glass and erects or oblique cutting rather than the mode that keeps flat save the space that slide glass specimen is put, it is possible to process more large batch of slide glass specimen；Slide glass specimen of the present utility model needs directly to heat to bay groove liquid filling during heating in processing procedure, it is not necessary to shift slide glass specimen when heat treatment so that the process of slide glass specimen is from start to finish carried out in same container.During heat treatment, even if producing volatilization, the liquid in gap can be automatically replenished due to capillarity, heat treatment is fully, uniformly, not producing withered phenomenon, this utility model makes that operating procedure is simpler, reliable, it is bigger to process specimen amount, and full-automatic operation flow process convenient to carry out.
Description
Technical field
This utility model belongs to biological sample process field, particularly relates to a kind of multichannel slide glass with heating function
Specimen incubating device.
Background technology
The whole process of immunohistochemistry needs nearly 30 steps, including: a) dewaxing, aquation, endogenous enzyme blocking-up,
Cleaning, high-temperature hot reparation, cool down, clean, one anti-hatch, clean, two anti-hatch, clean, synergist is hatched, clean, develop the color, clearly
Wash, serve as a contrast dye, clean, be dehydrated, the step such as mounting.Affected by the technical merit between hospital and hospital and operating habit difference,
It is difficult to standardize.The efficiency and the reliability that improve sample disposal become the task of top priority.
At present in checkout procedure, reagent pipetting volume sprays sample-adding above thin slice, and load position error is big, and reagent is in section
On covering with randomness, it is difficult to guaranteeing to cover whole section, some specimen do not obtain the covering of reagent and occur false cloudy
Property.Needing high-temperature heating during sample disposal, this is to make antigen or pathogen characteristic protein reply necessary to original shape
Step.Heating requirements reaches 80-100 DEG C or higher temperature and maintains 5-40 minute.Most common method be pressure cooker boil,
General boiling is boiled or the method such as hot water temperature bath.
But, the container of at present conventional slide glass sample disposal or carrier the most do not possess and can heat or the resistance to performance being heated.
Carry out in the midway of slide glass sample disposal needs slide glass specimen is transferred to heatable container, need the most again often to transfer to
On the operating board of temperature, add complexity and the operating error of operating process.
Realize slide glass specimen to carry out heat treated in position and just can simplify slide glass specimen processing operation step and be more easy to
In carrying out full-automatic operation flow process, meet simpler reliable, the requirement of higher efficiency of slide glass sample disposal.
Utility model content
In order to solve the problems referred to above, it is proposed that a kind of multichannel slide glass specimen incubating device with heating function, it is possible to
Process more large batch of section simultaneously and improve section response time in liquid reagent and operation with the further saving time
And raising efficiency, and fundamentally ensure the reproducibility and reliability of hot repair process.
A kind of multichannel slide glass specimen incubating device with heating function, it includes slide glass, cover plate, bay groove, heating
Device container, spike, lower discharge outlet, heating plate, add heat pipe, cover board support, spring leaf, electric magnet, upper water inlet；
Described cover board support is intervally arranged by array format and is fixed in bay groove；It is fixed with bullet on each cover board support
Reed；The molectron that slide glass and cover plate coordinate, inserts along the gap between cover board support and spring leaf, the surface of cover plate
Extrusion spring sheet, spring leaf produces spring pressure and is applied on slide glass and cover plate realize pressuring action；
Adding heat pipe to be embedded in heating plate, heating plate is arranged in heater canister；Add heat pipe to be connected with external power supply, and
Power and the time of heating is controlled by manual or controller；Add heat produced by heat pipe and pass to heating plate；Bay trench bottom
Or main body is made of metal；During energising, the heat pipe that adds of bottom is operationally placed on hot plate, accept the heat of heating plate with
Liquid in heating bay groove.
Further, bay groove is provided with discharge outlet, and heater canister is provided with lower discharge outlet；Upper discharge outlet, lower draining
Mouth is carried out discharge opeing by manual operation.
Further, bay groove is provided with discharge outlet, and heater canister is provided with lower discharge outlet；Upper discharge outlet, lower draining
Mouth is controlled discharge opeing by electric device (such as electromagnetic valve).
Further, bay groove can arrange string or multiple row cover board support, thus insert string or multiple row by carrying
The slide glass assembly that sheet cover plate and slide glass are adjacent to, forms array type close arrangement.
Further, a biological sample is at least contained above described slide glass.
Further, the material used is resistant to higher temperature, is generally possible to tolerate 80oMore than C and indeformable
Or soften.
Further, described device is provided with the heater of Contiuum type or separate type.
Further, the mode of heating of described heating plate, use disjunctor or separate type heating rod, heating plate, Electromagnetic Heating
Induction system heats, or carries out temperature bath heating to adding perfusion hot liquid in heat container.
Further, when needing heat treatment during slide glass sample disposal, directly in bay groove irrigate liquid and
Heat, it is not necessary to slide glass specimen being shifted in midway, the process of slide glass specimen is from start to finish carried out in a container.
Further, heater canister is provided with a spike；Heater canister is made up of insulation material, plays insulation
Effect.
Relative to prior art, this utility model has the following advantages and technique effect:
Device of the present utility model enables slide glass specimen in the way of setting or oblique angle setting rather than the mode of tiling
Place, can arrange with the array type close structure of multiple rows of multiple row；Slide glass assembly erect in the case of, the liquid in fine gap
Will not drain off, it is ensured that the slide glass specimen moment obtains the covering of reagent；Section preparation can directly soak or insert in hot solution uniform
Heating, volatilizees also due to fine from slide glass component bottom of capillarity even if the liquid in gap produces in heating process
Slit aperture sucks and is automatically replenished, and heating fully, does not produce withered phenomenon, ensures reliability and the repetition of hot repair process
Property；In device of the present utility model, all of accessory all uses heat proof material to make, and arrange disjunctor or separable heating
Device, as long as perfusion appearance liquid just can directly heat in bay groove, makes slide glass specimen from start to finish exist in processing procedure
Carry out in one container.
Accompanying drawing explanation
Fig. 1 is the structural representation of a kind of multichannel slide glass specimen incubating device with heating function of the present utility model
Figure.
Fig. 2 is the generalized section of Fig. 1.
Fig. 3 is the structural representation of heated base part of the present utility model.
Fig. 4 is the structural representation of bay groove of the present utility model.
Fig. 5 is the generalized section of Fig. 4.
Fig. 6 is the structural representation of slide glass of the present utility model and cover plate.
Fig. 7 a is the front view of slide glass assembly in Fig. 6；
Fig. 7 b is the A-A profile of Fig. 7 a；
Fig. 7 c is the enlarged diagram of the local B of Fig. 7 b.
Fig. 8 be one assign tank therefor in multiple row slide glass be set assign groove schematic diagram.
In figure: 1-slide glass；2-cover plate；3-bay groove；4-heater canister；5-props up spike；Discharge outlet under 6-；7-heats
Plate；8-electrothermal tube；9-cover board support；10-spring leaf；11-electric magnet；The upper water inlet of 12-and lower discharge outlet.
Detailed description of the invention
Below in conjunction with specific embodiment, the utility model is described in further detail, but is not limited to this.
As shown in Fig. 1 ~ Fig. 7, a kind of multichannel slide glass specimen incubating device with heating function, mainly include slide glass 1,
Cover plate 2, bay groove 3, heater canister 4, spike 5, lower discharge outlet 6, heating plate 7, electrothermal tube 8, cover board support 9, spring leaf
10, the parts such as electric magnet 11, upper discharge outlet 12.
Described cover board support 9 is fixed in bay groove 3, and array at a certain distance；It is fixed with on each cover board support 9
Spring leaf 10；The molectron that slide glass 1 and cover plate 2 coordinate, inserts along the gap between cover board support 9 and spring leaf 10,
The surface compacting spring leaf 10 of cover plate 2；Spring leaf 10, uses sheet copper, spring steel or other elastomeric material and elastic knot
It is configured to, produces spring pressure and be applied on slide glass 1 and cover plate 2 with both compressions.
As Fig. 6, Fig. 7 a ~ Fig. 7 c, slide glass 1 and cover plate 2 form one group of slide glass assembly for sample disposal, cover plate 2 has
Capillary plane, forms a capillary gap between slide surface and capillary plane；Described channel opening face 601 is connected with capillary plane
And to form angle be 1 ~ 175 degree of plane angle.
Adding heat pipe 8 to be embedded in heating plate 7, heating plate is arranged in heater canister 4；Add heat pipe 8 with external power supply even
Connect, and be not drawn into controlling power and the time of heating by controller；Add heat produced by heat pipe 8 and pass to heating plate 7.Bay
Groove 3 is made of metal, and is operationally placed in heating plate 7, accepts the heat of heating plate 7 with the liquid in heating bay groove 3.
Further, bay groove 3 is provided with electric magnet 11, when device is in heated condition, and controller () control in figure slightly
Electric magnet 11 processed is connected and is produced electromagnetic force, holds heating plate 7 and makes heating plate 7 and bay groove 3 be in close contact raising conduction of heat effect
Rate.
Further, the bottom of bay groove 3 is provided with discharge outlet 12, and heater canister 4 is provided with lower discharge outlet 6, on
Discharge outlet 12 is coaxial with lower discharge outlet 6；Upper discharge outlet 12 is provided with electromagnetism valve block () in figure slightly, can be by controller () control in figure slightly
The opening and closing of discharge outlet 12 in system.
Further, heater canister 4 is provided with a spike 5；Heater canister 4 is made up of insulation material, plays insulation
Heat insulation effect.
Further, each slide glass bay groove 3 can arrange string or multiple row cover board support, such that it is able to arrange installation
String or multiple row slide glass specimen.
Further, the material used is resistant to higher temperature, is generally possible to tolerate 80oMore than C and indeformable
Or fusing.
Further, the mode of heating of described heating plate 7, it is also possible to use Electromagnetic Heating or the similar container that has to add
The method of hot merit energy and the mode of employing perfusion hot liquid heat.
Further, described controller uses the controllers such as PIC single chip microcomputer, 51 single-chip microcomputers or PLC.
Such as Fig. 8, bay groove can arrange string or multiple row cover board support, thus insert string or multiple row by slide glass lid
The slide glass assembly that plate and slide glass are adjacent to, forms array type close arrangement.
According to announcement and the teaching of description above, this utility model those skilled in the art can also be to above-mentioned enforcement
Mode changes and revises.Therefore, this utility model is not limited to detailed description of the invention disclosed and described above, to this
Some modifications and changes of utility model should also be as falling in scope of the claims of the present utility model.
Claims (8)
1. a multichannel slide glass specimen incubating device with heating function, it is characterised in that include slide glass (1), cover plate (2),
Bay groove (3), heater canister (4), spike (5), lower discharge outlet (6), heating plate (7), add heat pipe (8), cover board support
(9), spring leaf (10), electric magnet (11), upper water inlet (12)；
Described cover board support (9) is intervally arranged by array format and is fixed in bay groove (3)；Each cover board support (9) is upper solid
Surely there is spring leaf (10)；The molectron that slide glass (1) and cover plate (2) coordinate, along cover board support (9) and spring leaf (10) it
Between gap insert, surface extrusion spring sheet (10) of cover plate (2), spring leaf (10) produce spring pressure be applied to slide glass (1)
Pressuring action is realized with on cover plate (2)；
Adding heat pipe (8) to be embedded in heating plate (7), heating plate is arranged in heater canister (4)；Add heat pipe (8) and external electricity
Source connects, and is controlled power and the time of heating by manual or controller；Add heat produced by heat pipe (8) and pass to heating plate
(7)；Bay groove (3) bottom or main body are made of metal；During energising, the heat pipe (8) that adds of bottom is operationally placed on heating plate
(7), on, the heat of heating plate (7) is accepted with the liquid in heating bay groove (3).
A kind of multichannel slide glass specimen incubating device with heating function the most according to claim 1, it is characterised in that:
Bay groove (3) is provided with discharge outlet (12), and heater canister is provided with lower discharge outlet (6)；Upper discharge outlet (12), lower discharge outlet
(6) discharge opeing is carried out by manual operation.
A kind of multichannel slide glass specimen incubating device with heating function the most according to claim 1, it is characterised in that:
Bay groove (3) is provided with discharge outlet (12), and heater canister is provided with lower discharge outlet (6)；Upper discharge outlet (12), lower discharge outlet
(6) discharge opeing is controlled by electric device.
A kind of multichannel slide glass specimen incubating device with heating function the most according to claim 1, it is characterised in that:
Bay groove (3) can arrange string or multiple row cover board support, thus insert string or multiple row and pasted by slide glass cover plate and slide glass
Slide glass assembly tightly, forms array type close arrangement.
A kind of multichannel slide glass specimen incubating device with heating function the most according to claim 1, it is characterised in that:
Described slide glass (1) the most at least contains a biological sample.
A kind of multichannel slide glass specimen incubating device with heating function the most according to claim 1, it is characterised in that:
Described device is provided with the heater of Contiuum type or separate type.
A kind of multichannel slide glass specimen incubating device with heating function the most according to claim 1, it is characterised in that:
The mode of heating of described heating plate (7), uses disjunctor or separate type heating rod, heating plate, Electromagnetic Heating induction system to add
Heat, or carry out temperature bath heating to adding perfusion hot liquid in heat container.
A kind of multichannel slide glass specimen incubating device with heating function the most according to claim 1, it is characterised in that:
Heater canister (4) is provided with a spike (5)；Heater canister (4) is made up of insulation material, plays the effect of insulation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620216820.9U CN205808807U (en) | 2016-03-21 | 2016-03-21 | A kind of multichannel slide glass specimen incubating device with heating function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620216820.9U CN205808807U (en) | 2016-03-21 | 2016-03-21 | A kind of multichannel slide glass specimen incubating device with heating function |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205808807U true CN205808807U (en) | 2016-12-14 |
Family
ID=58144693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620216820.9U Withdrawn - After Issue CN205808807U (en) | 2016-03-21 | 2016-03-21 | A kind of multichannel slide glass specimen incubating device with heating function |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205808807U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105675383A (en) * | 2016-03-21 | 2016-06-15 | 广州深达生物制品技术有限公司 | Multichannel slide specimen incubation device having heating function |
-
2016
- 2016-03-21 CN CN201620216820.9U patent/CN205808807U/en not_active Withdrawn - After Issue
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105675383A (en) * | 2016-03-21 | 2016-06-15 | 广州深达生物制品技术有限公司 | Multichannel slide specimen incubation device having heating function |
| CN105675383B (en) * | 2016-03-21 | 2019-06-14 | 厦门通灵生物医药科技有限公司 | A kind of multichannel slide glass sample incubating device with heating function |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190104 Address after: 361028 Floor 3 and 4 of Building B10, Xiamen Biomedical Industrial Park, 2068 Wengjiao West Road, Haicang District, Xiamen City, Fujian Province Patentee after: Xiamen Tongling biological medicine technology Co., Ltd. Address before: 511458 North 502 Software Building of Nansha Information Technology Park, Nansha Development Zone, Guangzhou City, Guangdong Province Patentee before: ASCEND BIOTECHNOLOGY CO., LTD. |
|
| AV01 | Patent right actively abandoned | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20161214 Effective date of abandoning: 20190614 |