CN105699147B - A kind of multichannel slide glass installation slot apparatus - Google Patents
A kind of multichannel slide glass installation slot apparatus Download PDFInfo
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- CN105699147B CN105699147B CN201610160720.3A CN201610160720A CN105699147B CN 105699147 B CN105699147 B CN 105699147B CN 201610160720 A CN201610160720 A CN 201610160720A CN 105699147 B CN105699147 B CN 105699147B
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- 239000011521 glass Substances 0.000 title claims abstract description 96
- 238000009434 installation Methods 0.000 title claims abstract description 26
- 238000010438 heat treatment Methods 0.000 claims abstract description 31
- 239000000463 material Substances 0.000 claims abstract description 5
- 230000004807 localization Effects 0.000 claims description 21
- 235000014676 Phragmites communis Nutrition 0.000 claims description 16
- 239000007788 liquid Substances 0.000 claims description 12
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 3
- 229910000639 Spring steel Inorganic materials 0.000 claims description 3
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- 229910052802 copper Inorganic materials 0.000 claims description 3
- 239000010949 copper Substances 0.000 claims description 3
- 239000013013 elastic material Substances 0.000 claims description 3
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 3
- 238000005096 rolling process Methods 0.000 claims description 3
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 238000004140 cleaning Methods 0.000 description 4
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- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 238000003491 array Methods 0.000 description 1
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- 238000010276 construction Methods 0.000 description 1
- 239000000994 contrast dye Substances 0.000 description 1
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The present invention, which discloses one kind, can heat multichannel slide glass installation slot apparatus, and main includes pressing slot container, cover board, slide glass, flat spring, left side brackets, right side bracket and heating device, be made by slot container using heat-resisting material.Slot of the invention is erect or is obliquely installed, and compact can place multiple slide glass samples to be checked；Slide glass and cover board load and unload simple and convenient from slot；Sample can be heated and be kept the temperature in container, it is carried out so that not needing to be transferred to sample in other heatable container during sample disposal, realize that slide glass sample from start to finish carries out in the same device, in favor of simplifying manual steps or integrating automatic flow in conjunction with the instrument for having sample-adding function.The section preparation moment obtains the covering of reagent, the reproducibility and reliability for improving heat treatment process, simplifies operating procedure, improves the quality of sample disposal and convenient for being integrated into full-automatic operation during the present invention ensures sample disposal.
Description
Technical field
The invention belongs to biological sample process fields, install slot apparatus more particularly to a kind of multichannel slide glass.
Background technique
Immunohistochemistry whole process needs nearly 30 steps, comprising: a) dewaxing, aquation, cleaning, high temperature hot repair
It is multiple, cooling, cleaning, primary antibody is incubated for, cleans, drains and wipes, secondary antibody is incubated for, cleans, drains and wipes, synergist incubation, clearly
It washes, drain and wipes, develop the color, cleaning, serving as a contrast dye, cleaning, dehydration, mounting.By the technical level between hospital and hospital
With the influence of operating habit difference, it is difficult to standardize.The efficiency and reliability for improving sample disposal becomes the task of top priority.
At present in checkout procedure, sample slice tiling is placed, and is taken up space big；Reagent pipetting volume sprays above thin slice to be added
Sample, load position error is big, and covering of the reagent on slice has randomness, it is difficult to ensure whole slice of covering, some samples
It does not obtain the covering of reagent and false negative occurs.It needs to be heated at high temperature during sample disposal, this is to make antigen or pathogen
Characteristic protein replys step necessary to original shape.Antigen or the reinstatement of pathogen characteristic protein are to maintain entire detection special
Anisotropic vital factor.80-100 DEG C of heating requirements or higher temperature simultaneously maintain 5-40 minutes.Most common method is high
Pressure pot boils, generally boiling is boiled or the methods of hot water warm bath.
However, the container or carrier of currently used slide glass sample disposal, which do not have, heating function or to be had resistance to heated
Performance.It needs for slide glass sample to be transferred in heatable container in the midway of slide glass sample disposal and carry out, then need again
It is transferred on the station of room temperature, increases the complexity and operating error of operating process.
Realize that slide glass sample carries out heat treatment in situ and can greatly simplify slide glass specimen processing operation step, improve
The repeatability of slide glass sample disposal result and be easier to carry out full-automatic operation process, it is simpler to meet slide glass sample disposal
Single reliable requirement.
Summary of the invention
To solve the above-mentioned problems, slot apparatus is installed the invention proposes a kind of multichannel slide glass, cover board and slide glass it
Between precision-fit form the sub-assembly of a relative closure, the container of sample disposal is arranged inclined installation slot, can make group
The compact placement of component occupies minimum space；Slide glass cover board forms fine gap when combining with slide glass, which can produce hair
Thin siphonage, so that sample-adding reagent passes through sample of the capillary siphonage uniform fold on slide glass；Of the invention assigns slot
Device makes using heat-resisting material and has Contiuum type or separate type heating device.Meet simultaneously and saves space, section preparation
Sample-adding is uniformly reliable, the requirement that can heat in situ etc..
The purpose of the present invention is realized at least through one of following technical solution.
A kind of multichannel slide glass installation slot apparatus, including press slot container, cover board, slide glass, flat spring, left side brackets
With right side bracket；It is mirror image between left side brackets and right side bracket, the two collectively forms slide glass and cover plate combination part
Installation slot rest, slot rest and slide glass cover plate assembly are installed and are located at by slot container；Left side brackets include side plate and
It is fixed on the U-type groove of the more than one prominent plate face on side plate, more than one U-type groove is along side plate length linear array cloth
It sets, U-type groove is made of bracer of drawing money on credit, short supporting block and bottom limited block；The length of the bracer of drawing money on credit is longer than short supporting block,
And both sides are parallel；U-type groove is obliquely installed and short supporting block is located on bracer of drawing money on credit；Flat spring includes the wave to link into an integrated entity
Shape wave reed and positioning plate；Waveform reed is located at a side of positioning plate and has an opening between positioning plate, makes
Obtaining flat spring can cover in left side brackets and right side bracket in the short supporting block of mirror symmetry；Positioning plate is fixed on short supporting block
On, support force is generated, waveform reed has the wavy bulge that can generate flexible deformation；Group made of slide glass and cover board cooperation
Component is inserted into along the U-type groove of bracket, and the waveform reed of the surface rolling flat spring of cover board, waveform reed is squeezed
It generates spring pressure to be applied on slide glass and cover board, be compressed using between slide glass and cover board.
Advanced optimize ground, installation slot rest bottom is provided with pedestal so that slide glass and cover plate combination part with press slot
Container bottom is kept at a distance.
Ground is advanced optimized, the inclined angle of U-type groove is 1 ~ 90 degree.
Ground is advanced optimized, the inclined angle of U-type groove is 15 ~ 90 degree.
Ground is advanced optimized, the waveform reed and positioning plate of flat spring use sheet copper, spring steel or other
Elastic material is made；Positioning plate is fixed in short supporting block by bonding way.
Ground is advanced optimized, the upper ends of slide glass are for adhesive label and bar code or identification label；The multiple U
There are spacing between type groove, so that the bar code of slide glass is pasted position and are not blocked by adjacent slide glass.
Ground is advanced optimized, each by one or more columns per page peace slot rest can be set in slot container, makes slide glass sample
It is pressing in slot container with single row or multiple rows and single-row or multiple rows of close-packed arrays.
Ground is advanced optimized, by the installation slot rest in slot container more than one column of setting, and be wherein parallel to each other
In two neighboring installation slot rest, also there is the more than one U-type groove between adjacent left side brackets and right side bracket
Structure also forms the installation slot rest between that is, adjacent left side brackets and right side bracket.
Ground is advanced optimized, the inserted sheet quantity of U-type groove can be configured 1- as needed in each column installation slot rest
100, usually 2 ~ 50 (i.e. 2-50 row).Slot rest is installed by described in slot container setting multiple row laid parallel, or every
It is a that slot rest is installed by described in multiple row laid parallel settable in slot container, form the slide glass of the cloth configuration of multiple rows of multiple row
The arrangement of sample.1-100 row and 1 ~ 100 column can be set as needed, 2-50 row and 1-40 column normally can be set.
Ground is advanced optimized, multichannel slide glass installs slot apparatus using tolerance 80oThe material of C temperatures above is made.
Ground is advanced optimized, inlet valve, outlet valve are set by slot container bottom, for manually or automatically controlling container
To liquid and drain；
Ground is advanced optimized, it is described to give liquid and drain by external plug-in type to liquid and drainage system by slot container
Control.
Ground is advanced optimized, the cover board includes capillary plane, depth localization face, width locating piece, bottom locating piece, slot
Side and channel opening face；Two upper sides of the capillary plane are provided with two depth localization faces, capillary plane and depth localization
Face is parallel；There are two the depth localization face is total, it is located at the left and right sides of capillary plane；The plane of the slide glass is close to two
The part of side edge is closed with depth localization face paste, makes to form a capillary gap between slide surface and capillary plane；Each depth
It spends the outer ledge on positioning surface far from capillary plane and is equipped with the more than one width locating piece；Two locating pieces in left and right it
Between distance match with the width of slide glass to play position-limiting action；The bottom end in depth localization face is arranged in bottom locating piece；It is described
Channel opening face connect with capillary plane and forms 1-175 degree angle A1, usually 30-105 degree；Channel opening face two sides are respectively connected with one
A slot side；The channel opening face and two slot sides and slide glass plane collectively form one and add with the capillary gap area
Sample slot.
Compared with the existing technology, the present invention has the following advantages that and technical effect:
Every group of slot of the invention can be set by multiple slide glass samples are inserted, and multiple rows of slide glass sample can be assigned by forming a column
Assign slot；Single row or multiple rows and single-row or multiple row setting of structuring the formation individually or disjunctor setting can be formed between the column and the column, it can
Closely assign the slide glass sample to be checked of volume；Cooperation between slide glass and cover board is compact accurate, generate a capillary gap with
Ensure that slide glass sample obtains the covering of reagent always；Slide glass and cover board load and unload simple and convenient from slot；Have by slot apparatus
It is heat-resisting and can heating function, sample in by slot container can sufficiently, be evenly heated and keep the temperature, fundamentally ensure hot repair process
Reproducibility and reliability.Container can be resistant to higher temperature, thus when needing high-temperature to handle during sample disposal not
Need separately handle then the step of reconfiguring in need in piece cover board and slide glass, may be implemented piece sample from start to finish
It is carried out in the same device, simplifies manual operations, when in conjunction with the instrument with sample-adding function, can integrated and help certainly
Dynamicization operating process.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of one of example multichannel slide glass installation slot apparatus.
Fig. 2 is the structural schematic diagram of one of example multichannel slide glass installation slot apparatus (removing container).
Fig. 3 is the structural representation of one of example multichannel slide glass installation slot apparatus (removing container and right side bracket)
Figure.
Fig. 4 is the front projection view of Fig. 3.
Fig. 5 is the partial enlargement diagram of Fig. 3.
Fig. 6 is the structural schematic diagram of bracket.
Fig. 7 is the front projection view of Fig. 6.
Fig. 8 is the structural schematic diagram of flat spring.
Fig. 9 is the structural schematic diagram of slide glass and slide glass cover plate combination part.
Figure 10 is a kind of exemplary construction schematic diagram of improvement of cover board.
Figure 11 is structural schematic diagram of the present invention in conjunction with heated base.
Figure 12 is the diagrammatic cross-section of Figure 11.
Figure 13 is the structural schematic diagram that multiple rows of multiple row slide glass slot is arranged in the present invention.
Specific embodiment
Although embodiments of the present invention are in attached drawing present invention encompasses various modifications and alternative method and device
It is middle to show and will be described in more detail below.It is, however, to be understood that specific description and attached drawing are not intended to limit the invention to institute
Disclosed concrete form.
As shown in Fig. 1 ~ Fig. 5, a kind of multichannel slide glass installation slot apparatus, main includes by slot container 1, cover board 2, load
The components such as piece 3, flat spring 4, left side brackets 5, right side bracket 6,
Left side brackets 5 and right side bracket 6 belong to the character shape of mirror symmetry, and the two collectively forms slide glass cover plate assembly
Slot rest is installed, the spacing of the two can be adjusted as needed；Such as Fig. 6, Fig. 7, left side brackets 5 are provided with more than one projecting plate
The U-type groove in face, the U-type groove include draw money on credit bracer 51, short supporting block 52 and bottom limited block 53；The length of the bracer 51 of drawing money on credit
It is longer than short supporting block 52, and both sides are parallel；The U-type groove is fixed on side plate 54, and is erect or tilted and put, and angle is 1 ~ 90
It spends, usually 15-90 degree；The U-type groove arranges that the number of rows and columns of arrangement can with single and multiple rows of and single-row and multiple row array
It is arranged according to user demand.It is that one group of slide glass and cover plate assembly are located in a U-type groove described in dotted line in Fig. 5.
Such as Fig. 8, flat spring 4 includes waveform reed 41 and positioning plate 42, using sheet copper, spring steel or other
Elastic material is made；There is an opening between waveform reed 41 and positioning plate 42, flat spring 4 is allowed to put on short branch
On bracer 52；Positioning plate 42 is fixed in short supporting block 52 by modes such as bondings, generates support force；The wave of waveform reed 41
Shape wave protrusion, can form certain flexible deformation.
Sub-assembly made of slide glass 3 and cover board 2 cooperate is inserted into, the surface rolling template of cover board 2 along the U-type groove of bracket
The waveform reed of spring 4 generates spring pressure and is applied on slide glass 3 and cover board 2 to compress the two, in order to avoid in the dead of night.
Slide glass cover plate assembly by left side brackets 5 and right side bracket 6 and thereon is mounted on by slot container 1, bracket bottom
Portion is provided with pedestal 55, so that slide glass 3 and 2 sub-assembly of cover board keep certain distance with by 1 bottom of slot container, convenient for heating liquid
Bottom hot-spot phenomenon is circulated and avoided in bottom.
Further implement ground, the upper ends of slide glass 3 are for adhesive label and bar code or identification label etc.；Left side branch
Appropriately distance should be kept between the multiple U-type grooves being arranged on frame 5 and right side bracket 6.
Further, one column installation slot rest of left side brackets 5 and the composition of right side bracket 6, each column install slot rest
It is 1 ~ 100 that the quantity of middle U-type groove can be configured as needed, can assign 1-100 slide glass samples, usually 2-50.
Such as Figure 13, the parallel installation slot rest of multiple row can be set as needed by slot container 1, can be set 1 ~ 100
Column, usually 1-40 is arranged；Each group (column) installation slot rest includes left side brackets 5 and right side bracket 6；Adjacent two rows of installations are inserted
Adjacent left side brackets 5 and right side bracket 6 can also permeate part in slot bracket, as long as having both left side brackets 5 and right side
The function of bracket 6.
Further, can be arranged water inlet valve and a drain valve (in figure slightly) in the container bottom, water valve can be manually or
Electrically operated valve, for manually or automatically control container to liquid and drain；The container gives liquid and drain, can also be by outer
The plug-in type set is carried out to liquid and drainage system.
Such as Fig. 9, Figure 10, further implement ground, cover board just can also be optimized and be improved, such as is preferred as one
Example, the cover board include capillary plane 101, depth localization face 102, width locating piece 103, bottom locating piece 104, slot side
106 and channel opening face 107；
Two upper sides of the capillary plane 101 are provided with two depth localization faces 102, and capillary plane 101 and depth are fixed
Plane is parallel；There are two the depth localization face 102 is total, it is located at the left and right sides of capillary plane 101；The slide glass is put down
Face is bonded close to the part of both sides of the edge with depth localization face 102, makes to form a hair between slide surface and capillary plane 101
Fine crack gap；Outer ledge on each depth localization face 102 far from capillary plane 101 is equipped with the more than one width positioning
Block 103；The distance between two locating pieces in left and right are matched with the width of slide glass to play position-limiting action；Bottom locating piece 104 is set
Set the bottom end in depth localization face 102；The bottom end of capillary plane 101 is provided with bottom boss 105.
The channel opening face 107 connect with capillary plane 101 and forms 1 ~ 175 degree of Plane Angle angle A1；Channel opening face 107
Two sides are respectively connected with a slot side 106；The channel opening face 107 and two slot sides 106 and slide glass plane collectively form one
A loading slot 109 with the capillary gap area.
It further include positioned at the heating device by 1 bottom part down of slot container, heating device such as Figure 11, Figure 12, in this example
It is Contiuum type or separate structure with slot container 1 is pressed, for example uses disjunctor or separate type heating rod, heating sheet, electromagnetic heating
Induction system carries out electromagnetic induction heating or perfusion hot liquid carries out warm bath heating.Heating tube is provided in heating plate 122 (in figure
Slightly), it is mounted in heater canister 123；Heating tube is connect with external power supply, and by the function of controller (in figure slightly) control heating
Rate and time；Heat transfer caused by heating tube is to heating plate 122.It is made of metal by slot container 1, places at work
In heating plate 122, receive the heat of heating plate 122 to heat by the liquid in slot container 1.By the top of slot container 1
It is provided with water inlet 124 and bottom is provided with lower discharge outlet 112, upper water inlet 124 and lower discharge outlet 112 are coaxial；It is enterprising
The mouth of a river and lower discharge outlet 124 are provided with valve (in figure slightly), can be by the upper and lower mouth of a river of manually or electrically controller (in figure slightly) control
124 opening and closing.Heater canister 123 is provided with support leg 111；Heater canister 123 is made of thermal insulation material, plays thermal insulation separation
The effect of heat.
Case study on implementation: slide glass cover board is sized such that 2 length 54mm of depth localization face, in two width locating pieces 3
The distance between side is 20mm, D1=0.15mm, D2=0.5mm, and the length of capillary plane is 40mm, width 20mm, channel opening
Angle between face and depth localization face is 30 degree.The length 75mm of slide glass, width 25mm.U-shaped slot tilts 45 degree, long support
Spacing 7mm between block and short supporting block, container depth 41mm.Multichannel slide glass installs slot apparatus using tolerance 80oC or more
(such as polycarbonate) is made in the material of temperature.Experiment shows that slot compact can insert multiple slide glasses slide glass sample to be checked；Slide glass
And the cooperation between cover board is compact accurate；Slide glass and cover board load and unload simple and convenient from slot；Sample in a reservoir can sufficiently,
Even heating and heat preservation fundamentally ensure the reproducibility and reliability of hot repair process, ensure reagent to sample from start to finish complete
All standing, the uniformity and repeatability for ensureing reagent covering.
The slot of this example can be erect or be obliquely installed, and compact can place multiple slide glass samples to be checked；Slide glass and cover board it
Between cooperation it is compact accurate；Slide glass and cover board load and unload simple and convenient from slot；Sample can be heated and be kept the temperature in container,
It is carried out so that not needing to be transferred to sample in other heatable container during sample disposal, in favor of simplifying manual operations
Step or reorganization automatic flow, and fundamentally ensure sample disposal during required for hot repair process reliability and
Repeatability ensures the uniformity and repeatability for being completely covered, ensureing reagent covering of reagent from start to finish to sample.Container can be with
Tolerance higher temperature simultaneously has Contiuum type or separate type heating function, thus when needing high-temperature to handle during sample disposal
Do not need separately handle then the step of reconfiguring in need in piece cover board and slide glass, may be implemented piece sample from begin to
It is carried out in the same device eventually, is convenient for full-automatic operation.
According to the disclosure and teachings of the above specification, those skilled in the art in the invention can also be to above-mentioned embodiment party
Formula is changed and is modified.Therefore, the invention is not limited to the specific embodiments disclosed and described above, to of the invention
Some modifications and changes should also be as falling into the scope of the claims of the present invention.
Claims (10)
1. a kind of multichannel slide glass installs slot apparatus, it is characterised in that including by slot container (1), cover board (2), slide glass (3),
Flat spring (4), left side brackets (5) and right side bracket (6)；
It is mirror image between left side brackets (5) and right side bracket (6), the two collectively forms slide glass (3) and cover board (2) group
The peace slot rest of component, installs slot rest and slide glass cover plate assembly is located at by slot container (1)；Left side brackets (5) packet
The U-type groove of more than one prominent plate face for including side plate (54) and being fixed on side plate (54), more than one U-type groove is along side plate
(54) length linear array is arranged, U-type groove is made of bracer of drawing money on credit (51), short supporting block (52) and bottom limited block (53)；Institute
The length for stating bracer of drawing money on credit (51) is longer than short supporting block (52), and both sides are parallel；U-type groove is obliquely installed and short supporting block (52) position
On bracer of drawing money on credit (51), the inclined angle of U-type groove is 1 ~ 90 degree；
Flat spring (4) includes the waveform reed (41) and positioning plate (42) to link into an integrated entity；Waveform reed (41) is located at
One side of positioning plate (42) and between positioning plate (42) have one opening so that flat spring (4) can cover in left side
On bracket (5) and right side bracket (6) in the short supporting block (52) of mirror symmetry；Positioning plate (42) is fixed on short supporting block (52)
On, support force is generated, waveform reed (41) has the wavy bulge that can generate flexible deformation；
Sub-assembly made of slide glass (3) and cover board (2) cooperation, is inserted into, the surface rolling plate of cover board (2) along the U-type groove of bracket
The waveform reed of type spring (4), waveform reed, which is squeezed, to be generated spring pressure and is applied on slide glass (3) and cover board (2), is made
It is compressed between slide glass (3) and cover board (2).
2. a kind of multichannel slide glass according to claim 1 installs slot apparatus, it is characterised in that: installation slot rest bottom
Portion is provided with pedestal (55), so that slide glass (3) and cover board (2) sub-assembly are kept at a distance with by slot container (1) bottom.
3. a kind of multichannel slide glass according to claim 1 installs slot apparatus, it is characterised in that: further include being located at by slotting
The heating device of tank therefor (1) bottom part down, heating device are Contiuum type or separate structure with slot container (1) is pressed.
4. a kind of multichannel slide glass according to claim 1 installs slot apparatus, it is characterised in that: flat spring (4)
Waveform reed (41) and positioning plate (42) are made of sheet copper, spring steel or other elastic materials；Positioning plate (42)
It is fixed on short supporting block (52) by bonding way.
5. a kind of multichannel slide glass according to claim 1 installs slot apparatus, it is characterised in that: left side brackets (5) and
One column installation slot rest of right side bracket (6) composition, each column can assign one or more slide glass sample.
6. a kind of multichannel slide glass according to claim 5 installs slot apparatus, it is characterised in that: press slot container (1)
Installation slot rests more than middle one column of setting, and in the two neighboring installation slot rest being wherein parallel to each other, an adjacent left side
Between side stand (5) and right side bracket (6) also have the more than one U-type groove structure, i.e., adjacent left side brackets (5) and
Also the installation slot rest is formed between right side bracket (6).
7. a kind of multichannel slide glass according to claim 1 installs slot apparatus, it is characterised in that: the installation of multichannel slide glass
Slot apparatus is using tolerance 80oThe material of C temperatures above is made.
8. a kind of multichannel slide glass according to claim 1 installs slot apparatus, it is characterised in that: the installation of multichannel slide glass
Slot apparatus carries out electromagnetic induction heating or perfusion hydrothermal solution using disjunctor or separate type heating rod, heating sheet, EM induction system
Body carries out warm bath heating.
9. a kind of multichannel slide glass according to claim 1 installs slot apparatus, it is characterised in that: press slot container (1)
Inlet valve and outlet valve is arranged in bottom, for slot container manually or automatically controlled to liquid and drain；Or it is described
Give liquid and drain can also be by external plug-in type to liquid and drainage system by slot container (1).
10. a kind of multichannel slide glass according to claim 1 installs slot apparatus, it is characterised in that: the cover board includes
Capillary plane, depth localization face, width locating piece, bottom locating piece, slot side and channel opening face；The two sides of the capillary plane
There are two depth localization face, capillary plane is parallel with depth localization face for top setting；There are two the depth localization face is total, respectively
Positioned at the left and right sides of capillary plane；The plane of the slide glass is closed close to the part of both sides of the edge with depth localization face paste, makes to carry
A capillary gap is formed between piece surface and capillary plane；Outer ledge on each depth localization face far from capillary plane is set
There is the more than one width locating piece；The distance between two width locating pieces in left and right are matched with the width of slide glass to play
Position-limiting action；The bottom end in depth localization face is arranged in bottom locating piece；The channel opening face connect and forms 1 with capillary plane ~
175 degree of plane angles (A1)；Channel opening face two sides are respectively connected with a slot side；The channel opening face and two slot sides and slide glass
Plane collectively forms the loading slot of one with the capillary gap area.
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| CN106248470A (en) * | 2016-08-31 | 2016-12-21 | 广州深达生物制品技术有限公司 | A kind of slide mount device of slide glass sample disposal |
| CN108132172A (en) * | 2016-12-01 | 2018-06-08 | 辽东学院 | Multifunctional combination dye vat |
| CN109061233B (en) * | 2018-07-27 | 2024-07-30 | 广州华望半导体科技有限公司 | Multipurpose drawer and trolley thereof |
| EP3874313A2 (en) * | 2018-11-02 | 2021-09-08 | Hologic, Inc. | Digital imaging system and method |
| CN114354317B (en) * | 2022-01-14 | 2024-07-05 | 厦门通灵生物医药科技股份有限公司 | Convertible support and detection device thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09196565A (en) * | 1996-01-23 | 1997-07-31 | San Techno:Kk | Extending device |
| CN201173665Y (en) * | 2008-01-28 | 2008-12-31 | 杨桂芹 | Pathological slide glass rack |
| CN203425848U (en) * | 2013-08-26 | 2014-02-12 | 内蒙古民族大学 | Dyeing glass slide airing frame |
| CN204269452U (en) * | 2014-10-24 | 2015-04-15 | 内蒙古民族大学 | An a kind of sheet dyeing apparatus for chromosome sectioning |
| CN205719679U (en) * | 2016-03-21 | 2016-11-23 | 广州深达生物制品技术有限公司 | Slot apparatus installed by a kind of multichannel slide glass |
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| US10429279B2 (en) * | 2013-07-28 | 2019-10-01 | Xmd, Llc | Devices and cartridges for extracting bio-sample regions and molecules of interest |
-
2016
- 2016-03-21 CN CN201610160720.3A patent/CN105699147B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09196565A (en) * | 1996-01-23 | 1997-07-31 | San Techno:Kk | Extending device |
| CN201173665Y (en) * | 2008-01-28 | 2008-12-31 | 杨桂芹 | Pathological slide glass rack |
| CN203425848U (en) * | 2013-08-26 | 2014-02-12 | 内蒙古民族大学 | Dyeing glass slide airing frame |
| CN204269452U (en) * | 2014-10-24 | 2015-04-15 | 内蒙古民族大学 | An a kind of sheet dyeing apparatus for chromosome sectioning |
| CN205719679U (en) * | 2016-03-21 | 2016-11-23 | 广州深达生物制品技术有限公司 | Slot apparatus installed by a kind of multichannel slide glass |
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