CN205251540U - Ultrasound stimulation and EEG signal collection probe of integration - Google Patents

Ultrasound stimulation and EEG signal collection probe of integration Download PDF

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Publication number
CN205251540U
CN205251540U CN201520708059.6U CN201520708059U CN205251540U CN 205251540 U CN205251540 U CN 205251540U CN 201520708059 U CN201520708059 U CN 201520708059U CN 205251540 U CN205251540 U CN 205251540U
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CN
China
Prior art keywords
eeg signal
screw thread
electrode
transducer
ultrasound stimulation
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Expired - Fee Related
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CN201520708059.6U
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Chinese (zh)
Inventor
袁毅
王怀宝
马志涛
王红
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Yanshan University
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Yanshan University
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Priority to CN201520708059.6U priority Critical patent/CN205251540U/en
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Publication of CN205251540U publication Critical patent/CN205251540U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model provides an ultrasound stimulation and EEG signal collection probe of integration, the probe is including focus ultrasonic transducer and brain electricity electrode, focus ultrasonic transducer for cavity focus ultrasonic transducer, transmission supersound part be the bowl form, the supersound is launched and focus on laboratory sample through the bowl form is partial. Cavity focus ultrasonic transducer's hollow portion has the screw thread. The brain electricity electrode of brain electricity electrode for having external screw thread, brain electricity electrode is connected with laboratory sample and is used for taking notes EEG signal. The external screw thread of brain electricity electrode is connected with the built -in screw thread of cavity focus transducer, forms the probe of integration, can carry out the cranial nerve regulation and control simultaneously and detect with EEG signal. The utility model has the advantages of simple structure, control convenience, regulation and control and monitoring synchronization.

Description

A kind of integrated ultrasound stimulation and eeg signal acquisition probe
Technical field
The invention belongs to Non-destructive Testing Technique, particularly a kind of integrated ultrasound stimulation and eeg signal acquisition probe.
Background technology
Low-intensity TCD,transcranial Doppler cranial nerve stimulating technology is a kind of new brain stimulation method growing up in recent years, there is not damaged, high spatial resolution, the high feature that stimulates the degree of depth, ultrasonic wave is a kind of mechanical pressure ripple, gains the name to be greater than people's earshot (2KHz-20KHz). Ultrasonic wave has the good characteristic that penetrates solid structure, comprises Bone and soft tissue, and therefore ultrasonic wave is widely used in medical treatment. Ultrasonicly can be sent to tissue with the form of impulse wave or continuous wave, cause the physiological change of tissue by fuel factor or mechanical effect. Thereby low-intensity TCD,transcranial Doppler stimulates a kind of technological means that refers generally to penetrate complete large bones of cerebral cranium and reach with low-strength focusing ultrasonic the modulation to nervous function, it has security, the permanent side effect of nothing, controllability, nothing wound, invertibity, neither destroy brain tissue or nerve, also do not affect other new treatment from now on. Eeg recording can, to the explanation of the variation quantitative of brain neurological motion before and after stimulating, be a kind of method of evaluating effect of stimulation with analyzing. But research is in the past mostly that ultrasound stimulation is separated with EEG signals with patent, the variation of EEG signals when monitoring ultrasound stimulation that can not be real-time.
Summary of the invention
The object of the invention is to provide a kind of manipulation convenient, rational in infrastructure, stimulates with EEG signals and records integrated ultrasound stimulation and eeg signal acquisition probe.
For achieving the above object, adopted following technical scheme: probe of the present invention comprises focused transducer and electrode for encephalograms; Described focused transducer be hollow focused transducer, transmitting ultrasound portion is divided into bowl-shape, is ultrasonicly divided transmitting and is focused on laboratory sample by bowl-shaped part. The hollow space of described hollow focused transducer is threaded. Described electrode for encephalograms is the electrode for encephalograms with external screw thread, and electrode for encephalograms is connected and is used for recording EEG signals with laboratory sample. The external screw thread of described electrode for encephalograms is connected with the built-in screw thread of hollow focused transducer, forms integrated probe, can carry out cranial nerve regulation and control simultaneously and detect with EEG signals.
Specific works process is as follows:
The EEG signals electrode of integrated ultrasound stimulation and eeg signal acquisition probe is connected with the built-in screw thread of hollow focused transducer hollow space by external screw thread, the bowl-shaped part of focused transducer is divided the impulse ultrasound sending, be radiated at rat head, cause that by mechanical effect nervous physiology changes. The electrode for encephalograms of integrated ultrasound stimulation and eeg signal acquisition probe is for recording the EEG signals of stimulation location
Compared with prior art, tool of the present invention has the following advantages:
1, the ultrasonic wave of ultrasonic transducer transmitting focuses on neural position, can stimulate nerve expeditiously;
2, electrode for encephalograms can be realized synchronizeing of eeg signal acquisition and ultrasound stimulation with ultrasonic transducer.
Brief description of the drawings
Fig. 1 is structured flowchart of the present invention.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention will be further described:
As shown in Figure 1, integrated ultrasound stimulation and eeg signal acquisition probe comprise: 1 hollow focused transducer, the built-in screw thread of 2 transducer, the external screw thread of 3 electrode for encephalograms, 4 electrode for encephalograms, 5 samples.
Probe of the present invention comprises focused transducer and electrode for encephalograms; Described focused transducer be hollow focused transducer, transmitting ultrasound portion is divided into bowl-shape, is ultrasonicly divided transmitting and is focused on laboratory sample by bowl-shaped part. The hollow space of described hollow focused transducer is threaded. Described electrode for encephalograms is the electrode for encephalograms with external screw thread, and electrode for encephalograms is connected and is used for recording EEG signals with laboratory sample. The external screw thread of described electrode for encephalograms is connected with the built-in screw thread of hollow focused transducer, forms integrated probe, can carry out cranial nerve regulation and control simultaneously and detect with EEG signals.
Described ultrasonic transducer be the ultrasonic transducer of inner hollow.
The focusing length of described focused transducer is greater than 30mm.
The diameter of the hollow space of described focused transducer is 5mm
Described electrode for encephalograms silver chlorate patch electrode
The external screw thread of described electrode for encephalograms be directly 4.9mm
Above-described embodiment is described the preferred embodiment of the present invention; not scope of the present invention is limited; design under the prerequisite of spirit not departing from the present invention; various distortion that those of ordinary skill in the art make technical scheme of the present invention, improvement, modification, substitute, combination, simplify, all should fall in the definite protection domain of the claims in the present invention book.

Claims (8)

1. an integrated ultrasound stimulation and eeg signal acquisition probe, is characterized in that: probe of the present invention comprises focused transducer and electrode for encephalograms; Described focused transducer be hollow focused transducer, it is bowl-shape that described focused transducer is launched being shaped as of ultrasonic part, the hollow space of described hollow focused transducer is threaded, described electrode for encephalograms is to be connected with the external screw thread of electrode for encephalograms described in the electrode for encephalograms of external screw thread and the built-in screw thread of hollow focused transducer, form integrated probe, can carry out cranial nerve regulation and control simultaneously and detect with EEG signals.
2. the integrated ultrasound stimulation of one according to claim 1 and eeg signal acquisition probe, is characterized in that: the ultrasonic transducer that described focused transducer is self-focusing.
3. the integrated ultrasound stimulation of one according to claim 1 and eeg signal acquisition probe, is characterized in that: described electrode for encephalograms is silver chlorate powder electrode.
4. the integrated ultrasound stimulation of one according to claim 1 and eeg signal acquisition probe, is characterized in that: the focusing length of described ultrasonic transducer is greater than 30mm.
5. the integrated ultrasound stimulation of one according to claim 1 and eeg signal acquisition probe, is characterized in that: the ultrasonic transducer that described focused transducer is inner hollow.
6. the integrated ultrasound stimulation of one according to claim 1 and eeg signal acquisition probe, is characterized in that: the ultrasonic transducer with sleeve arrangement that described focused transducer is inner hollow.
7. the integrated ultrasound stimulation of one according to claim 1 and eeg signal acquisition probe, is characterized in that: described focused transducer is embedded with screw thread with sleeve arrangement inside.
8. the integrated ultrasound stimulation of one according to claim 1 and eeg signal acquisition probe, is characterized in that: outside, described electrode for encephalograms upper end is embedded with screw thread.
CN201520708059.6U 2015-09-14 2015-09-14 Ultrasound stimulation and EEG signal collection probe of integration Expired - Fee Related CN205251540U (en)

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Application Number Priority Date Filing Date Title
CN201520708059.6U CN205251540U (en) 2015-09-14 2015-09-14 Ultrasound stimulation and EEG signal collection probe of integration

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Application Number Priority Date Filing Date Title
CN201520708059.6U CN205251540U (en) 2015-09-14 2015-09-14 Ultrasound stimulation and EEG signal collection probe of integration

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107692974A (en) * 2017-10-25 2018-02-16 上海交通大学 A kind of multi-parameter animal cortex blood flow monitoring device and method
CN108310685A (en) * 2018-03-01 2018-07-24 西安电子科技大学 A kind of wearable mouse brain stimulation ultrasonic transducer
CN108829238A (en) * 2018-05-04 2018-11-16 天津大学 A kind of brain-computer interface means of communication based on ultrasonic modulation
CN109718481A (en) * 2017-10-31 2019-05-07 深圳先进技术研究院 Ultrasonic neuromodulation system, method and the storage medium for treating addictive disorders
CN110292359A (en) * 2019-07-09 2019-10-01 浙江大学 A kind of method and apparatus of unmarked full optical neuron regulation and imaging
CN111938628A (en) * 2020-09-01 2020-11-17 天津大学 Electroencephalogram source signal detection device based on transcranial focused ultrasound stimulation
CN114366044A (en) * 2021-12-14 2022-04-19 广东省科学院健康医学研究所 Skin microvascular reactivity test system and method based on local pressure induction

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107692974A (en) * 2017-10-25 2018-02-16 上海交通大学 A kind of multi-parameter animal cortex blood flow monitoring device and method
CN109718481A (en) * 2017-10-31 2019-05-07 深圳先进技术研究院 Ultrasonic neuromodulation system, method and the storage medium for treating addictive disorders
CN108310685A (en) * 2018-03-01 2018-07-24 西安电子科技大学 A kind of wearable mouse brain stimulation ultrasonic transducer
CN108829238A (en) * 2018-05-04 2018-11-16 天津大学 A kind of brain-computer interface means of communication based on ultrasonic modulation
CN110292359A (en) * 2019-07-09 2019-10-01 浙江大学 A kind of method and apparatus of unmarked full optical neuron regulation and imaging
CN111938628A (en) * 2020-09-01 2020-11-17 天津大学 Electroencephalogram source signal detection device based on transcranial focused ultrasound stimulation
CN111938628B (en) * 2020-09-01 2024-01-23 天津大学 Brain power supply signal detection device based on transcranial focusing ultrasonic stimulation
CN114366044A (en) * 2021-12-14 2022-04-19 广东省科学院健康医学研究所 Skin microvascular reactivity test system and method based on local pressure induction
CN114366044B (en) * 2021-12-14 2023-08-25 广东省科学院健康医学研究所 Skin microvascular reactivity test system and method based on local pressure induction

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160525

Termination date: 20170914

CF01 Termination of patent right due to non-payment of annual fee