CN204618497U - A kind of Biodegradable scaffold - Google Patents

A kind of Biodegradable scaffold Download PDF

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Publication number
CN204618497U
CN204618497U CN201520297637.1U CN201520297637U CN204618497U CN 204618497 U CN204618497 U CN 204618497U CN 201520297637 U CN201520297637 U CN 201520297637U CN 204618497 U CN204618497 U CN 204618497U
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CN
China
Prior art keywords
support
curved unit
crest
connector
biodegradable scaffold
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201520297637.1U
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Chinese (zh)
Inventor
安桂生
迈克尔·贝恩
杨运燕
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TIANJIN SUOMA TECHNOLOGY Co Ltd
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TIANJIN SUOMA TECHNOLOGY Co Ltd
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Priority to CN201520297637.1U priority Critical patent/CN204618497U/en
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Publication of CN204618497U publication Critical patent/CN204618497U/en
Expired - Fee Related legal-status Critical Current
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Abstract

This utility model provides a kind of Biodegradable scaffold, be prepared from by biodegradable fiber, the tube wall of described support is the network structure of hollow out, described network structure is made up of some curved unit and the connector between described curved unit, connects into described network structure between two often adjacent curved unit according to the mode that crest-crest is corresponding or crest-trough is corresponding by described connector.Said structure makes whole support take into account under compliance, transporting, the good prerequisite of compliance, also there is suitable radial support power and longitudinal strength with metal rack, improve the integrally-built mechanically supportive of polymer support, make polymer support when life-time service, still can provide desirable mechanical support, not easily elastical retraction occur; And this support is easily degraded, not only environmental protection but also safety.

Description

A kind of Biodegradable scaffold
Technical field
This utility model belongs to medical instruments field, especially relates to a kind of Biodegradable scaffold being applied to the standard treatments of Percutantnoeus coronary intervention.
Background technology
Coronary heart disease refers to that seriously atherosis or spasm occurs the blood vessel-coronary artery of supply cardiotrophin material, make coronary stricture or obstruction, and thrombosis causes obliteration, causes a class heart disease of myocardial ischemia-anoxemia or infraction.
Coronary stenting has become the standard treatments of Percutantnoeus coronary intervention.The design of degradable blood vessel inner support (BDS, also known as biological absorbable support) based on overcome the long-term implant into body of bare metal stent cause stent restenosis and late period Thrombosis in sten, problems such as image check artifact, again myocardial revascularization difficulty such as CT and MRI and occurring.
BDS mono-aspect can support blood vessels in a short time, reaches the object of myocardial revascularization, on the other hand finally can degradation in vivo.Therefore, BDS short-term can reduce blood vessel elasticity retraction and acute occlusion in theory, prevention of restenosis, Thrombosis in sten can be reduced for a long time, shorten the Antiplatelet therapy time, reduce myocardial revascularization rate again, eliminate the artifact of the image checks such as CT and MRI, avoid the bad complication that metal permanent support causes.
But BDS support is compared with metal permanent support, its maximum deficiency is because BDS support is mostly polymer support, so its mechanical property is subject to certain restrictions, life-time service often can not ensure support force in the same manner as metal rack, and early stage elastical retraction more easily occurs.And support is to life-time service, need to have enough mechanical support power, after angiostenosis expansion, the high-risk stage of elastical retraction provides desirable mechanical support, can not cave in the normal activity of patient.
Structural design due to support can affect the attribute such as transporting, compliance, structural support, radial support power, longitudinal strength of support, therefore to support, there is different performances, its structural design becomes particularly important, the compliance of existing polymer support and motility are general all better, and support force is often inadequate, therefore will design can life-time service and can biodegradable polymer support be exactly mainly the support force problem of solution polymer support.
Utility model content
In view of this, this utility model is intended to the Biodegradable scaffold proposing a kind of structure optimization, to solve the Problems existing such as bare metal stent and polymer support in prior art.
For achieving the above object, the technical solution of the utility model is achieved in that
A kind of Biodegradable scaffold, be prepared from by biodegradable fiber, the tube wall of described support is the network structure of hollow out, described network structure is made up of some curved unit and the connector between described curved unit, connects into described network structure between two often adjacent curved unit according to the mode that crest-crest is corresponding or crest-trough is corresponding by described connector.
Preferably, described biodegradable fiber is Poly-L-lactic acid fiber.
Preferably, described curved unit is wavy curve structure or fold-line-shaped curvilinear structures.
Preferred, the curve of described curved unit is one or both the combination in sine curve, cosine curve, triangle, conic section.
The shape of described support is cylindrical.
The length of described connector is 3/1 to four/4ths of the wavelength of described curved unit.
Described connector is between the paddy-peak of adjacent two curved unit or peak-to-peak.
Described connector be equally uniformly distributed between adjacent two curved unit or non-equidistant spaced apart.
Relative to prior art, Biodegradable scaffold described in the utility model has following advantage:
Biodegradable scaffold described in the utility model, be prepared from by biodegradable fiber, the tube wall of described support is the network structure of hollow out, this network structure is made up of some curved unit and connector, whole network structure is connected into according to the mode that crest-crest is corresponding or crest-trough is corresponding by described connector between two often adjacent curved unit, said structure makes whole support take into account compliance, transporting, under the good prerequisite of compliance, also there is suitable radial support power and longitudinal strength with metal rack, improve the integrally-built mechanically supportive of polymer support, make polymer support when life-time service, still can provide desirable mechanical support, not easily there is elastical retraction, and this support is easily degraded, not only environmental protection but also safety.
Accompanying drawing explanation
The accompanying drawing forming a part of the present utility model is used to provide further understanding of the present utility model, and schematic description and description of the present utility model, for explaining this utility model, is not formed improper restriction of the present utility model.In the accompanying drawings:
Fig. 1 is the flat deployable structure schematic diagram of the using state 1 of support described in the utility model;
Fig. 2 is the flat deployable structure schematic diagram of the using state 2 of support described in the utility model;
Fig. 3 is the flat deployable structure schematic diagram of the using state 3 of support described in the utility model;
Fig. 4 is the flat deployable structure schematic diagram of the using state 4 of support described in the utility model;
Fig. 5 is the perspective view of the using state 1 of support described in the utility model.
Detailed description of the invention
It should be noted that, when not conflicting, the embodiment in this utility model and the feature in embodiment can combine mutually.
Below with reference to the accompanying drawings and describe this utility model in detail in conjunction with the embodiments.
Biodegradable scaffold of the present utility model, be prepared from by biodegradable fiber (common is Poly-L-lactic acid fiber), the tube wall of this support is the network structure of hollow out, described network structure is made up of some curved unit 1 and the connector between described curved unit 2, connects into described network structure between two often adjacent curved unit 1 according to the mode that crest-crest is corresponding or crest-trough is corresponding by described connector 2.
Wherein, described curved unit 1 is the elementary cell of composition support, according to submissive type required by the environment for use of reality and mechanical strength, curved unit 1 can be designed to wavy curve structure or fold-line-shaped curvilinear structures, such as, in sine curve, cosine curve, triangle, conic section a kind of or the wherein combination of two kinds, the supporting structure plane outspread drawing of Fig. 1-4 is the structure of four kinds of embodiments that sine and cosine curved unit alternate combinations is formed, the three-dimensional structure diagram of the cylindrical stent that Fig. 5 is formed for wherein a kind of embodiment.
Under using state described in FIG, described connector 2 is all between the paddy-peak of adjacent two curved unit, and with the crest of each curved unit or trough one_to_one corresponding, connector 2 is dense distribution relatively, make the mechanical performance of whole support comparatively strong, corresponding compliance reduces, and the environment be applicable to for mechanical property requirements is higher uses, and in order to keep good mechanical performance, the length of connector 2 is 3/1 to four/4ths of the wavelength of described curved unit.
Fig. 2, 3, the distribution of the connector 2 in 4 is all relatively sparse relative to Fig. 1, and sparse situation increases gradually, the distribution mode being embodied in the connecting rod between two adjacent between two curved unit to be equidistantly uniformly distributed closely, equidistantly spaced apartly to combine with non-equidistant is spaced apart, the overall mechanical properties of relative support also can decrease, compliance strengthens, therefore can by the adjustment for the number of connector 2 or position (such as in actual use procedure, connector is between the paddy-peak of adjacent two curved unit or peak-to-peak, the mode such as connector is equally uniformly distributed between adjacent two curved unit or non-equidistant is spaced apart), adjust the mechanical property of whole support further, make it better play a role, the crest of each curved unit or the height of trough also can be designed to identical or different according to practical service environment in addition, and the radius of curvature of each summit end also can change, in supporting structure, the thickness of curved unit or connector also can be identical or different with width, better to fit environment for use, plays better medical effect.
The foregoing is only preferred embodiment of the present utility model; not in order to limit this utility model; all within spirit of the present utility model and principle, any amendment done, equivalent replacement, improvement etc., all should be included within protection domain of the present utility model.

Claims (8)

1. a Biodegradable scaffold, be prepared from by biodegradable fiber, it is characterized in that: the tube wall of described support is the network structure of hollow out, described network structure is made up of some curved unit and the connector between described curved unit, connects into described network structure between two often adjacent curved unit according to the mode that crest-crest is corresponding or crest-trough is corresponding by described connector.
2. Biodegradable scaffold according to claim 1, is characterized in that: described biodegradable fiber is Poly-L-lactic acid fiber.
3. Biodegradable scaffold according to claim 1, is characterized in that: described curved unit is wavy curve structure or fold-line-shaped curvilinear structures.
4. the Biodegradable scaffold according to claim 1 or 3, is characterized in that: the curve of described curved unit is one or both the combination in sine curve, cosine curve, triangle, conic section.
5. Biodegradable scaffold according to claim 1, is characterized in that: the shape of described support is cylindrical.
6. Biodegradable scaffold according to claim 1, is characterized in that: the length of described connector is 3/1 to four/4ths of the wavelength of described curved unit.
7. Biodegradable scaffold according to claim 1, is characterized in that: described connector is between the paddy-peak of adjacent two curved unit or peak-to-peak.
8. Biodegradable scaffold according to claim 1, is characterized in that: described connector be equally uniformly distributed between adjacent two curved unit or non-equidistant spaced apart.
CN201520297637.1U 2015-05-08 2015-05-08 A kind of Biodegradable scaffold Expired - Fee Related CN204618497U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201520297637.1U CN204618497U (en) 2015-05-08 2015-05-08 A kind of Biodegradable scaffold

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201520297637.1U CN204618497U (en) 2015-05-08 2015-05-08 A kind of Biodegradable scaffold

Publications (1)

Publication Number Publication Date
CN204618497U true CN204618497U (en) 2015-09-09

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105902331A (en) * 2016-04-08 2016-08-31 南京永明医疗器械有限公司 Intravascular stent and preparation method thereof
CN106726003A (en) * 2016-12-30 2017-05-31 上海长海医院 Dissection of aorta intravascular stent and its manufacture method
CN106726037A (en) * 2017-01-04 2017-05-31 北京航空航天大学 A kind of PLA base intravascular stent that can uniformly degrade
CN108852571A (en) * 2018-07-13 2018-11-23 四川兴泰普乐医疗科技有限公司 A kind of self-expansion type biodegradable polymer stent and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105902331A (en) * 2016-04-08 2016-08-31 南京永明医疗器械有限公司 Intravascular stent and preparation method thereof
CN106726003A (en) * 2016-12-30 2017-05-31 上海长海医院 Dissection of aorta intravascular stent and its manufacture method
CN106726037A (en) * 2017-01-04 2017-05-31 北京航空航天大学 A kind of PLA base intravascular stent that can uniformly degrade
CN108852571A (en) * 2018-07-13 2018-11-23 四川兴泰普乐医疗科技有限公司 A kind of self-expansion type biodegradable polymer stent and preparation method thereof

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CF01 Termination of patent right due to non-payment of annual fee
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Granted publication date: 20150909