CN106726003A - Dissection of aorta intravascular stent and its manufacture method - Google Patents
Dissection of aorta intravascular stent and its manufacture method Download PDFInfo
- Publication number
- CN106726003A CN106726003A CN201611257682.XA CN201611257682A CN106726003A CN 106726003 A CN106726003 A CN 106726003A CN 201611257682 A CN201611257682 A CN 201611257682A CN 106726003 A CN106726003 A CN 106726003A
- Authority
- CN
- China
- Prior art keywords
- rack body
- aorta
- dissection
- intravascular stent
- wire
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2240/001—Designing or manufacturing processes
Abstract
The invention discloses a kind of dissection of aorta intravascular stent and its manufacture method, dissection of aorta intravascular stent includes rack body and is attached to the overlay film in the outside of rack body, and rack body is formed by multiple bung flange spirals, and each bung flange is made up of multiple waveforms.Manufacture method includes：By space cylindrical coordinate system, space continuous helical wavy curve is built；The threedimensional model of rack body is obtained by scan mode；The physical model of rack body is made according to threedimensional model；Wire is used to wind physical model to obtain rack body；To rack body thermal finalization and electropolishing；The outside electrospinning of rack body or hot pressing have overlay film.It is whole that the bending that intravascular stent occurs in the tube chamber of bending is uniformly distributed in intravascular stent, increased the applicating property of intravascular stent, it is to avoid bending and damages the situation of tube wall and occurs.And the intravascular stent aims at dissection of aorta design, simple structure is easy to operation, and support force is suitable, adapts to the pathological characteristic of dissection of aorta.
Description
Technical field
The present invention relates to a kind of intravascular stent, more particularly to a kind of dissection of aorta intravascular stent and its manufacture method.
Background technology
Dissection of aorta (aortic dissection, AD) refer to aortic tunica intima because there is breach in a variety of causes, actively
Blood flow in arteries and veins chamber enters aortic tunica media from aortic tunica intima breach, aortic tunica media is torn separation, and long along sustainer
Axially nearly distal end extension, so as to form a kind of pathological change in true and false two chamber of sustainer.The hurried harm of its onset is huge, tear
Vascular wall is weak, can form aneurysm or directly rupture and cause massive haemorrhage dead, and dissection of aorta is oppressed in true chamber after being formed,
The blood supply of sustainer important branch can be influenceed, the severe ischemic necrosis of important organ is caused, causes serious heart infarction, cerebral infarction etc. simultaneously
Hair disease is even dead.
Dissection of aorta EVAR is carried out at present, i.e., using the invasive methods of percutaneous stenter to implant, by blood
The intracavity implant that tube chamber is built into straight pipe type carrys out closed sandwich cut, struts true chamber and recovers normal blood supply, so as to reach treatment
Purpose.
Endovascular isolation implant is by tubular metal silk support and suture or the artificial blood vessel group being bonded on the inside of support
Into tubular metal silk support is formed through Z-fold back wall by elastic metallic yarn into Straight, and artificial blood vessel is by inert polymer material
Material is made, usually terylene or polytetrafluoroethylene (PTFE).It is loaded into conveyer after Endovascular isolation implant is compressed when using,
Aortic aneurysm is sent to by conveyer by distant place femoral artery or common iliac artery to be discharged again, because the elastic force of wire rack mount is made
With reverting to straight tube-like and being close to sustainer inwall automatically, diseased region is isolated with blood flow, so as to reach therapeutic purposes.
Without open operation, simple and direct minimally invasive, determined curative effect has successfully given treatment to large quantities of patients to this method.
However, traditional aorta tectorial membrane stent is designed for aortic aneurysm, its support force and compliance do not meet master
The pathologic, physiologic feature of artery dissection, causes postoperative the sticking in bad formation of dissection of aorta to be leaked, and support force crosses macrolesion tube wall
Cause that dissection of aorta is inverse to be torn.
Specifically, traditional aorta tectorial membrane stent is that multiple support rings are connected by the fabric or film of external application or suture
Connect and form, some supports can add longitudinal wire to improve longitudinal stability.Its maximum shortcoming is：Run into the blood of bending
During pipe portion position, the support of straight-tube shape can produce bending, and this bending is concentrated and the ring and ring of support between, rather than averagely
Distribution, so, local bending can cause thrombosis and support in chamber adherent bad, trigger such as aortic arch branch
Frame " beak phenomenon " (big curved side stand is adherent and lesser curvature side is tilted) and support distort the Kink at position, or even indulging due to support
Cause head end and pipe friction to stiff and damage tube wall or stent migration.So that the new intracavity implant system of exploitation
Unite to solve this problem.
The content of the invention
The present invention for prior art exist problem and shortage, there is provided a kind of new dissection of aorta intravascular stent and
Its manufacture method.
The present invention is to solve above-mentioned technical problem by following technical proposals：
The present invention provides a kind of dissection of aorta intravascular stent, and its feature is that it includes a rack body and an attachment
In the overlay film in the outside of the rack body, the rack body is formed by multiple bung flange spirals, and each bung flange is made up of multiple waveforms.
It is preferred that the waveform is sinusoidal waveform.
It is preferred that the waveform is cosine waveform.
It is preferred that the rack body is made up of wire.
It is preferred that the wire is stainless steel wire or nitinol alloy wire.
It is preferred that the rack body is made up of absorbable polymer silk.
The present invention also provides a kind of manufacture method of above-mentioned dissection of aorta intravascular stent, and its feature is that it includes
Following steps：
By space cylindrical coordinate system, space continuous helical wavy curve is built；
The threedimensional model of the rack body is obtained by scan mode；
The physical model of the rack body is made according to the threedimensional model；
Wire is used to wind the physical model to obtain the rack body；
To the rack body thermal finalization and electropolishing；
The outside electrospinning of the rack body or hot pressing have the overlay film；
Wherein, the cylindrical coordinates expression formula of the space continuous helical wavy curve：
R represents cylinder radius, and P represents pitch, and A represents wave amplitude, and n represents crest number weekly, and m represents the individual of spiral
Number.
The innovation of this manufacture method is：Can according to the concrete condition of the dissection of aorta of patient, to parameter R,
P, A, n and m select different numerical value, so as to obtain the different intravascular stents for being applicable patient, what this manufacture method was designed
Intravascular stent has more flexibility, more enough dissection of aorta for preferably matching patient.
It is preferred that the radius r scopes of the wire are 0mm<r≤1mm.
It is preferred that the radius r of the wire is 0.25mm or 0.3mm.
It is preferred that according to the threedimensional model laser engraving or the 3D printing physical model.
On the basis of common sense in the field is met, above-mentioned each optimum condition can be combined, and obtain final product each preferable reality of the present invention
Example.
Positive effect of the invention is：
The bending that the intravascular stent of continuous type occurs in the tube chamber of bending is uniformly distributed in intravascular stent whole process, increases
The applicating property of intravascular stent is added, it is to avoid bending and damage the situation of tube wall and occur.And the intravascular stent aims at aorta clamp
Layer design, simple structure is easy to operation, and support force is suitable, adapts to the pathological characteristic of dissection of aorta.
Brief description of the drawings
Fig. 1 is the structural representation of the rack body of the dissection of aorta intravascular stent of present pre-ferred embodiments.
Fig. 2 is the flow chart of the manufacture method of the dissection of aorta intravascular stent of present pre-ferred embodiments.
Specific embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention
In accompanying drawing, the technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is
A part of embodiment of the present invention, rather than whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art
The every other embodiment obtained on the premise of creative work is not made, belongs to the scope of protection of the invention.
The present embodiment provides a kind of dissection of aorta intravascular stent, and it includes that a rack body and is attached to support master
The overlay film in the outside of body.
As shown in figure 1, the rack body is formed by the spiral of multiple bung flanges 1,6 bung flanges 1, each bung flange are shown in Fig. 1
It is made up of multiple sinusoidal or cosine waveforms 2.
Wherein, the rack body is made up of wire, and the wire is stainless steel wire or nitinol alloy wire, and compliance is good.
Certainly, the rack body can also be absorbable polymer silk, can degrade within the scheduled time.The overlay film is absorbable or not
Absorbable polymer, can carry medicine, can be electrostatic spinning or hot-forming, and ultra-thin complaisant is good.
The radius r scopes of the wire are 0mm<r≤1mm.Preferably, the radius r of the wire be 0.25mm or
0.3mm。
As shown in Fig. 2 the present embodiment also provides a kind of manufacture method of above-mentioned dissection of aorta intravascular stent, it includes
Following steps：
Step 101, model is set up using SolidWorks, by space cylindrical coordinate system, build space continuous helical ripple
Shape (such as sine wave or cosine wave) curve；
Step 102, the threedimensional model that the rack body is obtained by scan mode；
Step 103, using customization frock, according to the threedimensional model laser engraving or the entity mould of the 3D printing rack body
Type；
Step 104, wire is used to wind the physical model to obtain the rack body；
Step 105, to the rack body thermal finalization and electropolishing；
Step 106, the outside electrospinning of the rack body or hot pressing have the overlay film.
Wherein, the cylindrical coordinates expression formula of the space continuous helical wavy curve：
R represents cylinder radius, and P represents pitch, and A represents wave amplitude, and n represents crest number weekly, and m represents the individual of spiral
Number.
The intravascular stent of the continuous type produced by the manufacture method aims at dissection of aorta design, in the tube chamber of bending
It is whole that the bending of middle generation is uniformly distributed in intravascular stent, increased the applicating property of intravascular stent, it is to avoid bending and damages
The situation for hindering tube wall occurs.And the intravascular stent simple structure is easy to operation, support force is suitable, adapts to the pathology of dissection of aorta
Feature.
Although the foregoing describing specific embodiment of the invention, it will be appreciated by those of skill in the art that these
It is merely illustrative of, protection scope of the present invention is defined by the appended claims.Those skilled in the art is not carrying on the back
On the premise of principle of the invention and essence, various changes or modifications can be made to these implementation methods, but these are changed
Protection scope of the present invention is each fallen within modification.
Claims (10)
1. a kind of dissection of aorta intravascular stent, it is characterised in that it includes that a rack body and is attached to the rack body
Outside overlay film, the rack body formed by multiple bung flange spirals, and each bung flange is made up of multiple waveforms.
2. dissection of aorta intravascular stent as claimed in claim 1, it is characterised in that the waveform is sinusoidal waveform.
3. dissection of aorta intravascular stent as claimed in claim 1, it is characterised in that the waveform is cosine waveform.
4. dissection of aorta intravascular stent as claimed in claim 1, it is characterised in that the rack body is made up of wire.
5. dissection of aorta intravascular stent as claimed in claim 4, it is characterised in that the wire is stainless steel wire or NiTi
B alloy wire.
6. dissection of aorta intravascular stent as claimed in claim 1, it is characterised in that the rack body is by absorbable polymer
Silk is made.
7. a kind of manufacture method of the dissection of aorta intravascular stent in 1-5 such as claim as described in any one, its feature exists
In it is comprised the following steps：
By space cylindrical coordinate system, space continuous helical wavy curve is built；
The threedimensional model of the rack body is obtained by scan mode；
The physical model of the rack body is made according to the threedimensional model；
Wire is used to wind the physical model to obtain the rack body；
To the rack body thermal finalization and electropolishing；
The outside electrospinning of the rack body or hot pressing have the overlay film；
Wherein, the cylindrical coordinates expression formula of the space continuous helical wavy curve：
R represents cylinder radius, and P represents pitch, and A represents wave amplitude, and n represents crest number weekly, and m represents the number of spiral.
8. the manufacture method of dissection of aorta intravascular stent as claimed in claim 7, it is characterised in that the radius of the wire
R scopes are 0mm<r≤1mm.
9. the manufacture method of dissection of aorta intravascular stent as claimed in claim 8, it is characterised in that the radius of the wire
R is 0.25mm or 0.3mm.
10. the manufacture method of dissection of aorta intravascular stent as claimed in claim 7, it is characterised in that according to the three-dimensional mould
Type laser engraving or the 3D printing physical model.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611257682.XA CN106726003B (en) | 2016-12-30 | 2016-12-30 | Dissection of aorta intravascular stent and its manufacture method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611257682.XA CN106726003B (en) | 2016-12-30 | 2016-12-30 | Dissection of aorta intravascular stent and its manufacture method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106726003A true CN106726003A (en) | 2017-05-31 |
| CN106726003B CN106726003B (en) | 2018-03-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611257682.XA Expired - Fee Related CN106726003B (en) | 2016-12-30 | 2016-12-30 | Dissection of aorta intravascular stent and its manufacture method |
Country Status (1)
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107242917A (en) * | 2017-07-05 | 2017-10-13 | 上海长海医院 | A kind of stent graft |
| CN108888391A (en) * | 2018-07-12 | 2018-11-27 | 北京龙慧珩医疗科技发展有限公司 | A kind of non-crossing bracket of monofilament |
| CN109044576A (en) * | 2018-08-24 | 2018-12-21 | 上海长海医院 | Aortic blood pressure controlled release carried stent and controlling of blood pressure drug delivery system |
| CN110923825A (en) * | 2019-09-02 | 2020-03-27 | 上海大学 | Preparation system and preparation method of high-elasticity drug-loaded thin film intravascular stent |
| CN114748118A (en) * | 2022-06-15 | 2022-07-15 | 迈迪威(深圳)实业有限公司 | Chest surgery auxiliary device based on traction distraction and using method |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111228003B (en) * | 2020-01-13 | 2022-12-09 | 李功俊 | Nickel-titanium alloy stent for treating megacolon disease |
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| US20140107762A1 (en) * | 2004-07-26 | 2014-04-17 | Abbott Cardiovascular Systems Inc. | Biodegradable stent with enhanced fracture toughness |
| WO2006081568A1 (en) * | 2005-01-28 | 2006-08-03 | Stent Tech, Inc. | Flexible cells for axially interconnecting stent components |
| CN101884574A (en) * | 2010-06-28 | 2010-11-17 | 河北工业大学 | Method and device for preparing three-dimensional porous support for tissue engineering |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107242917A (en) * | 2017-07-05 | 2017-10-13 | 上海长海医院 | A kind of stent graft |
| CN107242917B (en) * | 2017-07-05 | 2023-09-19 | 上海长海医院 | Stent graft |
| CN108888391A (en) * | 2018-07-12 | 2018-11-27 | 北京龙慧珩医疗科技发展有限公司 | A kind of non-crossing bracket of monofilament |
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| CN109044576B (en) * | 2018-08-24 | 2023-09-19 | 上海长海医院 | Aortic blood pressure controlled drug delivery stent and blood pressure controlled drug delivery system |
| CN110923825A (en) * | 2019-09-02 | 2020-03-27 | 上海大学 | Preparation system and preparation method of high-elasticity drug-loaded thin film intravascular stent |
| CN110923825B (en) * | 2019-09-02 | 2021-11-09 | 上海大学 | Preparation system and preparation method of high-elasticity drug-loaded thin film intravascular stent |
| CN114748118A (en) * | 2022-06-15 | 2022-07-15 | 迈迪威(深圳)实业有限公司 | Chest surgery auxiliary device based on traction distraction and using method |
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|---|---|
| CN106726003B (en) | 2018-03-13 |
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