CN105287048A - Filming support - Google Patents
Filming support Download PDFInfo
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- CN105287048A CN105287048A CN201410317721.5A CN201410317721A CN105287048A CN 105287048 A CN105287048 A CN 105287048A CN 201410317721 A CN201410317721 A CN 201410317721A CN 105287048 A CN105287048 A CN 105287048A
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- overlay film
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- matrix membrane
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Abstract
A filming support comprises a supporting structure and a film covering the supporting structure, wherein the film is composed of at least two stacked layers of allogeneic acellular tissue base film, the smooth side of each layer of the base film faces the supporting structure while the rough side faces out; the adjacent two layers of base film are arranged by crossing at a certain angle along a growth direction of a collagen bundle. In the at least two layers of the allogeneic acellular tissue base film, all base film is provided with a plurality of through holes expect for the innermost layer, and the hole diameter increases gradually from the inner layer to the outer layer. The use of the filming support is effective in reducing the formation of thrombus and endotheliosis, in enhancing film strength and reducing the axial tension of the film during the release of the filming support, and in adhering endothelial cells to promote cell differentiation to promote the ingrowth of tissues and vessels, and quickening the endothelialization of lesion areas of arterial aneurysm to give better effect in treating arterial aneurysm.
Description
Technical field
The present invention relates to medical apparatus and instruments, particularly relate to a kind of overlay film frame.
Background technology
Aneurysm is that the blood vessel wall local caused because of generation disease, damage or congenital factor due to arterial blood tube wall becomes weak, under the impact of bearing blood flow, the weak spot of this place's arterial blood tube wall outwardly, is expanded gradually, and the cryptomere of the circle of formation, ellipse or prismatic is expanded.Aneurysm is a kind of disease having potential life danger, and aneurysm constantly grows under the impact of blood flow, and compressing peripheral organs or tissue cause symptom.Due to the aneurysm rupture that blood pressure increases or other factors cause, there is sharply hemorrhage.Aneurysm can occur in the different parts of health, and modal is abdominal aortic aneurysm and intracranial aneurysm.For avoiding surgical operation excessive risk, intravascular Interventional Treatment becomes the aneurysmal main method for the treatment of gradually, and intravascular Interventional Treatment has that wound is little, few intercurrent disease, safety is high, patient suffering is few and the heavy also tolerant advantage of the year high state of an illness.Overlay film frame is as the aneurysmal a kind of device of vascular interventional treatment, a closed pipeline can be formed in lesion vessels, make diseased region blood flow and normal blood circulation completely isolated, in parent artery, re-establish channel of blood flow, reach cure aneurysmal object.
Overlay film frame generally comprises supporting construction and overlay film, overlay film is coated on the outside of supporting construction, the overlay film of prior art is the monolayer overlay film that homogenous material is made, material normally high molecular synthetic material or biological tissue's derived material such as polyurethane, politef, expanded polytetrafluoroethylsealing of this overlay film.Wherein the former biocompatibility is poor and cannot be degraded by human body, will produce comparatively serious inflammatory reaction in implant into body body; The biocompatibility of the latter is better, but mechanical property is poor, and surface porosity factor is lower, is unfavorable for cell attachment increment and will delays the healing of diseased region endothelialization.Monolayer structure of film intensity is poor, hold in overlay film frame pressure, discharge and in the process such as bending overlay film very easily damaged, in addition because monolayer overlay film pore structure is single, when support discharges because overlay film will be stretched, gap structure is out of shape thus the phenomenon of axial shortening easily occurs, and finally causes and cannot cover the situations such as diseased region completely.
Summary of the invention
Object of the present invention, exactly in order to solve the problem, provides a kind of novel overlay film frame.
In order to achieve the above object, present invention employs following technical scheme: a kind of overlay film frame, comprise supporting construction and coated overlay film on the support structure; Described overlay film is formed by least two-layer acellular periplast film is superimposed, and all towards supporting construction, matsurface is outwardly for the shiny surface of every layer of matrix membrane; The mode that adjacent two layers matrix membrane is crossed as certain angle by the collagenous fiber bundle direction of growth arranges.
In described at least two-layer acellular periplast film, except innermost layer matrix membrane, other matrix membrane is all provided with multiple perforation, and increases gradually to outer aperture from internal layer.
Adopt stitching, bonding between adjacent two layers acellular periplast film or combined by the coated power of overlay film self.
Described acellular periplast film is take pig, cattle, the lamellar of sheep or other animals or membranaceous tissue to make.
The intersecting angle of the collagenous fiber bundle direction of growth of described adjacent two layers matrix membrane is 0 ~ 90 degree but non-vanishing.
The aperture of described perforation is 0.1 μm-100 μm.
Compared with prior art, overlay film frame provided by the invention has following advantage and disadvantage:
1, because overlay film adopts at least two-layer acellular periplast film to form, the biocompatibility of overlay film frame can be improved preferably and increase simultaneously and cover film strength, preventing from holding in overlay film frame pressure, discharging and the breakage of overlay film in the process such as bending.
2, overlapping with certain angle of the crossing owing to adjacent two layers matrix membrane to be pressed the collagenous fiber bundle direction of growth, the phenomenon of the axial shortening of overlay film in stent-expansion process can be reduced as far as possible.
3, due to overlay film every layer matrix membrane all keep shiny surface towards supporting construction matsurface outwardly, shiny surface matter is close evenly has good blood compatibility, effectively can reduce formation and the endotheliosis of thrombosis.
4, because overlay film other matrix membrane except innermost layer matrix membrane is all provided with perforation, and from internal layer to skin every layer aperture in the trend increased gradually, the outer porosity of overlay film is increased while guarantee overlay film frame channel of blood flow, promote that cell differentiation is grown into impel tissue and blood vessel effectively to stick endotheliocyte, accelerate aneurysm diseased region endothelialization, to reach the effect of more effectively treating aneurysmal disease.
Accompanying drawing explanation
Fig. 1 is the structural representation of an embodiment of overlay film frame of the present invention;
Fig. 2 is the structural representation of another embodiment of overlay film frame of the present invention;
Fig. 3 is that two-layer matrix membrane is crossed as certain angle arrangement schematic diagram by the collagenous fiber bundle direction of growth.
Detailed description of the invention
See Fig. 1, Fig. 2, coordinate see Fig. 3.Overlay film frame of the present invention, comprises supporting construction 1 and coated overlay film 2 on the support structure.Overlay film 2 is wherein formed by least two-layer acellular periplast film is superimposed, adopts stitching, bonding or combined by the coated power of overlay film self between adjacent two layers acellular periplast film.All towards supporting construction, matsurface is outwardly for the shiny surface of every layer of matrix membrane; The mode that adjacent two layers matrix membrane is crossed as certain angle by the collagenous fiber bundle direction of growth arranges, and intersecting angle is 0 ~ 90 degree but non-vanishing.In Fig. 3, θ is for intersecting angle.
In at least two-layer acellular periplast film, except innermost layer matrix membrane, other matrix membrane is all provided with multiple perforation 21, the aperture of perforation is 0.1 μm-100 μm.And increase gradually from internal layer to outer aperture.
Acellular periplast film in the present invention is take pig, cattle, the lamellar of sheep or other animals or membranaceous tissue to make.
The shape of the present invention to overlay film frame is not particularly limited, and is preferably shape well known to those skilled in the art, includes but not limited to straight pipe type overlay film frame, webmaster type overlay film frame (as shown in Figure 1) and the overlay film frame with branch.The material of the present invention to supporting construction is not particularly limited, and is preferably material well known to those skilled in the art, includes but not limited to metal and high molecular polymer.The coated mode of the present invention to overlay film and supporting construction is not particularly limited, be preferably coated mode well known to those skilled in the art, include but not limited to described overlay film to sew up on the support structure and described overlay film is made tubular structure be enclosed within supporting construction outside.
Claims (6)
1. an overlay film frame, comprises supporting construction and coated overlay film on the support structure; It is characterized in that: described overlay film is formed by least two-layer acellular periplast film is superimposed, all towards supporting construction, matsurface is outwardly for the shiny surface of every layer of matrix membrane; The mode that adjacent two layers matrix membrane is crossed as certain angle by the collagenous fiber bundle direction of growth arranges.
2. overlay film frame as claimed in claim 1, is characterized in that: in described at least two-layer acellular periplast film, except innermost layer matrix membrane, other matrix membrane is all provided with multiple perforation, and increases gradually to outer aperture from internal layer.
3. overlay film frame as claimed in claim 1, is characterized in that: adopt stitching, bonding between adjacent two layers acellular periplast film or combined by the coated power of overlay film self.
4. overlay film frame as claimed in claim 1, is characterized in that: described acellular periplast film is take pig, cattle, the lamellar of sheep or other animals or membranaceous tissue to make.
5. overlay film frame as claimed in claim 1, is characterized in that: the intersecting angle of the collagenous fiber bundle direction of growth of described adjacent two layers matrix membrane is 0 ~ 90 degree but non-vanishing.
6. overlay film frame as claimed in claim 2, is characterized in that: the aperture of described perforation is 0.1 μm-100 μm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410317721.5A CN105287048B (en) | 2014-07-03 | 2014-07-03 | Overlay film frame |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410317721.5A CN105287048B (en) | 2014-07-03 | 2014-07-03 | Overlay film frame |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105287048A true CN105287048A (en) | 2016-02-03 |
| CN105287048B CN105287048B (en) | 2017-06-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410317721.5A Expired - Fee Related CN105287048B (en) | 2014-07-03 | 2014-07-03 | Overlay film frame |
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| CN (1) | CN105287048B (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105832332A (en) * | 2016-06-06 | 2016-08-10 | 任勇 | Thoracic descending aorta stent based aneurysm impedance monitoring device and thoracic descending aorta stent based aneurysm impedance monitoring method |
| CN105832333A (en) * | 2016-06-06 | 2016-08-10 | 任勇 | Device and method for monitoring tumor impedance and blood flow rates on basis of abdominal aortic stent |
| CN105943046A (en) * | 2016-06-06 | 2016-09-21 | 任勇 | Tumor body impedance monitoring device and method based on abdominal aortic stent |
| CN106955135A (en) * | 2017-04-07 | 2017-07-18 | 上海申淇医疗科技有限公司 | A kind of plugging device choked flow film and its manufacture method |
| CN107411845A (en) * | 2016-09-14 | 2017-12-01 | 四川蓝光英诺生物科技股份有限公司 | Lumen organization's construct, lumen organization's structure preparation and its device |
| CN107456296A (en) * | 2016-09-14 | 2017-12-12 | 四川蓝光英诺生物科技股份有限公司 | Lumen organization's construct, the preparation method of lumen organization's construct and preparation facilities |
| CN107693163A (en) * | 2017-11-29 | 2018-02-16 | 成都创客之家科技有限公司 | One kind can develop intravascular stent |
| CN107744414A (en) * | 2017-11-29 | 2018-03-02 | 成都创客之家科技有限公司 | A kind of film-coated vascular support |
| CN109259910A (en) * | 2018-05-21 | 2019-01-25 | 广州医科大学 | A kind of multilayer coating film airway stent and preparation method thereof |
| CN110292664A (en) * | 2018-03-21 | 2019-10-01 | 美敦力瓦斯科尔勒公司 | Tissue coating product |
| CN111388143A (en) * | 2020-04-17 | 2020-07-10 | 赵晓辉 | Intravascular stent with elastic energy storage section consisting of Z-shaped rings |
| CN112773559A (en) * | 2021-01-21 | 2021-05-11 | 宁波迪创医疗科技有限公司 | Novel covered stent |
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| CN1927413A (en) * | 2006-09-13 | 2007-03-14 | 重庆大学 | Amnion stroma tectorial blood vessel internal branch and preparing method thereof |
| CN101147814A (en) * | 2007-11-16 | 2008-03-26 | 蔡绪旺 | Blood vessel medicine support |
| CN101627933A (en) * | 2008-07-17 | 2010-01-20 | 微创医疗器械(上海)有限公司 | Covered stent |
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Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105832333A (en) * | 2016-06-06 | 2016-08-10 | 任勇 | Device and method for monitoring tumor impedance and blood flow rates on basis of abdominal aortic stent |
| CN105943046A (en) * | 2016-06-06 | 2016-09-21 | 任勇 | Tumor body impedance monitoring device and method based on abdominal aortic stent |
| CN105832332A (en) * | 2016-06-06 | 2016-08-10 | 任勇 | Thoracic descending aorta stent based aneurysm impedance monitoring device and thoracic descending aorta stent based aneurysm impedance monitoring method |
| CN107456296B (en) * | 2016-09-14 | 2020-07-14 | 四川蓝光英诺生物科技股份有限公司 | Lumen tissue construct, method and device for producing lumen tissue construct |
| CN107411845A (en) * | 2016-09-14 | 2017-12-01 | 四川蓝光英诺生物科技股份有限公司 | Lumen organization's construct, lumen organization's structure preparation and its device |
| CN107456296A (en) * | 2016-09-14 | 2017-12-12 | 四川蓝光英诺生物科技股份有限公司 | Lumen organization's construct, the preparation method of lumen organization's construct and preparation facilities |
| CN106955135A (en) * | 2017-04-07 | 2017-07-18 | 上海申淇医疗科技有限公司 | A kind of plugging device choked flow film and its manufacture method |
| CN107693163A (en) * | 2017-11-29 | 2018-02-16 | 成都创客之家科技有限公司 | One kind can develop intravascular stent |
| CN107744414A (en) * | 2017-11-29 | 2018-03-02 | 成都创客之家科技有限公司 | A kind of film-coated vascular support |
| CN110292664A (en) * | 2018-03-21 | 2019-10-01 | 美敦力瓦斯科尔勒公司 | Tissue coating product |
| CN109259910A (en) * | 2018-05-21 | 2019-01-25 | 广州医科大学 | A kind of multilayer coating film airway stent and preparation method thereof |
| CN111388143A (en) * | 2020-04-17 | 2020-07-10 | 赵晓辉 | Intravascular stent with elastic energy storage section consisting of Z-shaped rings |
| CN112773559A (en) * | 2021-01-21 | 2021-05-11 | 宁波迪创医疗科技有限公司 | Novel covered stent |
| WO2022156471A1 (en) * | 2021-01-21 | 2022-07-28 | 宁波迪创医疗科技有限公司 | Novel covered stent |
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| CN105287048B (en) | 2017-06-23 |
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Granted publication date: 20170623 Termination date: 20200703 |