CN204188515U - A kind of safflower concentration process near infrared online monitoring device - Google Patents
A kind of safflower concentration process near infrared online monitoring device Download PDFInfo
- Publication number
- CN204188515U CN204188515U CN201420164183.6U CN201420164183U CN204188515U CN 204188515 U CN204188515 U CN 204188515U CN 201420164183 U CN201420164183 U CN 201420164183U CN 204188515 U CN204188515 U CN 204188515U
- Authority
- CN
- China
- Prior art keywords
- near infrared
- waste discharge
- discharge mouth
- hand valve
- flow cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title claims abstract description 26
- 244000020518 Carthamus tinctorius Species 0.000 title claims abstract description 15
- 235000003255 Carthamus tinctorius Nutrition 0.000 title claims abstract description 15
- 238000012806 monitoring device Methods 0.000 title claims abstract description 9
- 239000000523 sample Substances 0.000 claims abstract description 24
- 239000002699 waste material Substances 0.000 claims abstract description 24
- 239000007788 liquid Substances 0.000 claims abstract description 18
- 239000003814 drug Substances 0.000 claims abstract description 10
- 238000006243 chemical reaction Methods 0.000 claims abstract description 9
- 238000001914 filtration Methods 0.000 claims abstract description 8
- 238000001228 spectrum Methods 0.000 claims abstract description 7
- 238000010438 heat treatment Methods 0.000 claims abstract description 4
- 238000009834 vaporization Methods 0.000 claims abstract description 4
- 230000008016 vaporization Effects 0.000 claims abstract description 4
- 238000005516 engineering process Methods 0.000 abstract description 5
- 238000010183 spectrum analysis Methods 0.000 abstract description 3
- 239000000470 constituent Substances 0.000 abstract description 2
- 238000002329 infrared spectrum Methods 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000003908 quality control method Methods 0.000 description 3
- WLYGSPLCNKYESI-RSUQVHIMSA-N Carthamin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1[C@@]1(O)C(O)=C(C(=O)\C=C\C=2C=CC(O)=CC=2)C(=O)C(\C=C\2C([C@](O)([C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)C(O)=C(C(=O)\C=C\C=3C=CC(O)=CC=3)C/2=O)=O)=C1O WLYGSPLCNKYESI-RSUQVHIMSA-N 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- DYQVDISPPLTLLR-HJQYTNQXSA-N Carthamin Natural products CC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)[C@]2(O)C(=C(C=C/3C(=O)C(=C(O)[C@](O)([C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C3=O)C(=O)C=Cc5ccc(O)cc5)C(=O)C(=C2O)C(=O)C=Cc6ccc(O)cc6)O DYQVDISPPLTLLR-HJQYTNQXSA-N 0.000 description 1
- 241000208809 Carthamus Species 0.000 description 1
- 239000003390 Chinese drug Substances 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- 230000002744 anti-aggregatory effect Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 210000004351 coronary vessel Anatomy 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000000916 dilatatory effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 238000004836 empirical method Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical compound [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 description 1
- 230000003116 impacting effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
Landscapes
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
A kind of safflower concentration process near infrared online monitoring device, comprise hand valve 1, duplex strainer, waste discharge mouth 1, frequency conversion micropump, waste discharge mouth 2, hand valve 2, flow cell (containing near-infrared fibre-optical probe), near infrared spectrometer, hand valve 3, sample tap, waste discharge mouth 3 and hand valve 4, liquid in concentrator heating chamber is delivered to duplex strainer by frequency conversion micropump, circulate after filtration pond, near-infrared fibre-optical probe is connected with near infrared spectrometer, for gathering the near infrared light spectrogram of flow cell inner liquid medicine, spectra collection collects liquid sample at sample tap place simultaneously, flow cell manually valve 4 is communicated with concentrator vaporization chamber.The utility model device can make near-infrared spectral analysis technology be applied to the concentrated link of Chinese medicine industry spot, realizes the on-line real-time measuremen to concentration process active constituent content and variable density.
Description
Technical field
The utility model relates to a kind of safflower concentration process near infrared online monitoring device, belongs to the technical field of the on-line checkingi of traditional Chinese drug inspissation process.
Background technology
Near-infrared spectrum technique as a kind of green analytical technology of quick nondestructive, have express-analysis, sample preparation simple, without the need to consuming the features such as reagent.In recent years, near-infrared spectrum technique is more and more applied to traditional Chinese medicine research, comprises that the medicinal material place of production is differentiated, the on-line checkingi of active principle assay and pharmacy procedure and monitoring.It seems from Recent study progress, near-infrared spectral analysis technology is hopeful one of process analysis technique realizing on-line checkingi and quality control at Chinese Traditional Medicine most.
Safflower has the effect of anti-freezing, anti-bolt, hemangiectasis and control cardiovascular and cerebrovascular disease.Hydroxyl radical carthamin yellow carthamus A is the main active of safflower, has coronary artery dilating, increases coronary flow, the effect of Antiaggregating activity on platelet.Concentrated is one of important procedure in safflower formulation manufacturing processes, is one of workshop section of power consumption, quality control relative difficult in production run.Conventional Concentrating Process Control is based on empirical method, consuming time longer, lack the on-line checkingi of active principle concentration, on-line monitoring is not carried out to the critical evaluation index of the evaluation concentration process qualities such as active principle concentration, density in concentration process, in the uncontrollable and concentration process easily causing striking point to be determined, active principle loss is uncontrollable, refining or the dry run that direct impact is follow-up, becomes the inhomogenous key factor of traditional Chinese medicine quality.Therefore research and development safflower concentration process on-Line Monitor Device, contribute to the line Quality Control problem solving crucial Con trolling index in safflower concentration process, for Chinese medicine industrial technological advancement and product quality upgrading, there is Great significance.
Utility model content
The utility model object is the on-line measuring device that the defect existed for prior art provides a kind of safflower concentration process.
The utility model for achieving the above object, adopts following technical scheme:
A kind of safflower concentration process of the utility model near infrared online monitoring device, comprise hand valve 1, duplex strainer, waste discharge mouth 1, frequency conversion micropump, waste discharge mouth 2, hand valve 2, flow cell (containing near-infrared fibre-optical probe), near infrared spectrometer, hand valve 3, sample tap, waste discharge mouth 3, hand valve 4, liquid in concentrator heating chamber is delivered to duplex strainer by frequency conversion micropump, circulate after filtration pond, near-infrared fibre-optical probe is connected with near infrared spectrometer, for gathering the near infrared light spectrogram of flow cell inner liquid medicine, spectra collection collects liquid sample at sample tap place simultaneously, flow cell manually valve 4 is communicated with concentrator vaporization chamber.
Liquid in described on-Line Monitor Device pipeline is by waste discharge mouth 1, waste discharge mouth 2, waste discharge mouth 3 effluent discharge.
Described near infrared spectrometer carries out spectra collection by near-infrared fibre-optical probe to the liquid in flow cell.
In described on-Line Monitor Device, flow velocity controls within 2L/min, and the filtering accuracy of duplex strainer is 80 microns.
The utility model device can guarantee the true, effective of the near infrared spectrum of Real-time Collection, make flow cell place pipeline herb liquid flow speed stability, the solid impurity that effective filtering concentration process produces, and then prevent flow velocity and the near infrared spectrum of impurity to online acquisition from impacting, near-infrared spectral analysis technology can be made to be applied to the concentrated link of Chinese medicine industry spot, to realize the on-line real-time measuremen to concentration process active constituent content and variable density.
Accompanying drawing explanation
Fig. 1: the utility model structural representation.
Embodiment:
A kind of safflower concentration process of the utility model near infrared online monitoring device, comprise hand valve 1, duplex strainer, waste discharge mouth 1, frequency conversion micropump, waste discharge mouth 2, hand valve 2, flow cell (containing near-infrared fibre-optical probe), near infrared spectrometer, hand valve 3, sample tap, waste discharge mouth 3, hand valve 4, liquid in concentrator heating chamber is delivered to duplex strainer by frequency conversion micropump, circulate after filtration pond, near-infrared fibre-optical probe is connected with near infrared spectrometer, for gathering the near infrared light spectrogram of flow cell inner liquid medicine, spectra collection collects liquid sample at sample tap place simultaneously, flow cell manually valve 4 is communicated with concentrator vaporization chamber.
Liquid in described on-Line Monitor Device pipeline is by waste discharge mouth 1, waste discharge mouth 2, waste discharge mouth 3 effluent discharge.
Described near infrared spectrometer carries out spectra collection by near-infrared fibre-optical probe to the liquid in flow cell.
In described on-Line Monitor Device, flow velocity controls within 2L/min, and the filtering accuracy of duplex strainer is 80 microns.
Waste discharge mouth 1, waste discharge mouth 2, waste discharge mouth 3 is closed before using the utility model, after 3 tons of Flos Carthami extract input concentration tanks are also arrived the thickening temperature and pressure preset, open hand valve 1, hand valve 2, hand valve 3, hand valve 4, start frequency conversion micropump, regulate frequency converter frequency, frequency converter frequency meets near infrared spectra collection requirement 17.00 ~ 23.00 time, and frequency 19.00 ~ 20.50 is best near infrared spectra collection condition, opens sample tap sampling while gathering spectrum.
The foregoing is only preferred embodiment of the present utility model, be not limited to the utility model, although be described in detail the utility model with reference to previous embodiment, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.All within spirit of the present utility model and principle, any amendment done, equivalent replacement, improvement etc., all should be included within protection domain of the present utility model.
Claims (3)
1. a safflower concentration process near infrared online monitoring device, it is characterized in that: comprise hand valve (1), duplex strainer, waste discharge mouth (1), frequency conversion micropump, waste discharge mouth (2), hand valve (2), flow cell, near infrared spectrometer, hand valve (3), sample tap, waste discharge mouth (3), hand valve (4), wherein, flow cell is containing near-infrared fibre-optical probe, liquid in concentrator heating chamber is delivered to duplex strainer by frequency conversion micropump, circulate after filtration pond, near-infrared fibre-optical probe is connected with near infrared spectrometer, for gathering the near infrared light spectrogram of flow cell inner liquid medicine, spectra collection collects liquid sample at sample tap place simultaneously, flow cell manually valve (4) is communicated with concentrator vaporization chamber.
2. a kind of safflower concentration process near infrared online monitoring device according to claim 1, is characterized in that: the liquid in on-Line Monitor Device pipeline is by waste discharge mouth (1), waste discharge mouth (2), waste discharge mouth (3) effluent discharge.
3. a kind of safflower concentration process near infrared online monitoring device according to claim 1, it is characterized in that: in on-Line Monitor Device, flow velocity controls within 2L/min, the filtering accuracy of duplex strainer is 80 microns.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420164183.6U CN204188515U (en) | 2014-04-08 | 2014-04-08 | A kind of safflower concentration process near infrared online monitoring device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420164183.6U CN204188515U (en) | 2014-04-08 | 2014-04-08 | A kind of safflower concentration process near infrared online monitoring device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN204188515U true CN204188515U (en) | 2015-03-04 |
Family
ID=52620498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420164183.6U Expired - Lifetime CN204188515U (en) | 2014-04-08 | 2014-04-08 | A kind of safflower concentration process near infrared online monitoring device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN204188515U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105928824A (en) * | 2016-05-25 | 2016-09-07 | 江苏康缘药业股份有限公司 | Honeysuckle flower and artemisia apiacea concentrated solution vacuum concentration extract density measuring device and control method thereof |
| CN109682776A (en) * | 2018-11-30 | 2019-04-26 | 丽水学院 | Multimode near infrared online monitors system and its application method |
| CN112924411A (en) * | 2019-12-06 | 2021-06-08 | 九芝堂股份有限公司 | Detection system and detection method for concentration process of Liuwei Dihuang pills |
-
2014
- 2014-04-08 CN CN201420164183.6U patent/CN204188515U/en not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105928824A (en) * | 2016-05-25 | 2016-09-07 | 江苏康缘药业股份有限公司 | Honeysuckle flower and artemisia apiacea concentrated solution vacuum concentration extract density measuring device and control method thereof |
| CN109682776A (en) * | 2018-11-30 | 2019-04-26 | 丽水学院 | Multimode near infrared online monitors system and its application method |
| CN112924411A (en) * | 2019-12-06 | 2021-06-08 | 九芝堂股份有限公司 | Detection system and detection method for concentration process of Liuwei Dihuang pills |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN203203920U (en) | Online detection device of extraction process of traditional Chinese medicine | |
| CN103913433B (en) | Online detection method for double-effect concentration process of danhong injection | |
| CN204188515U (en) | A kind of safflower concentration process near infrared online monitoring device | |
| CN207114423U (en) | A kind of Chinese medicine extracts online ultraviolet spectral analysis device | |
| CN104977271B (en) | A kind of safflower alcohol precipitation process active ingredient near infrared online detection method | |
| CN203414406U (en) | Online ultraviolet spectrum detection system in traditional Chinese medicine extraction process | |
| CN103923748A (en) | Volatile oil extracting, collecting and separating device | |
| CN104458963A (en) | Quality detection method for pseudo-ginseng oral preparation | |
| CN204439647U (en) | Laboratory COD automatic analyzer | |
| CN103965149A (en) | Aloin extraction method | |
| CN106334337A (en) | Traditional Chinese medicine extraction and concentration tank having near-infrared online detection function | |
| CN110346323B (en) | Method for detecting Huagaisan concentrated solution on line based on near infrared spectrum technology | |
| CN212532917U (en) | Multilayer control by temperature change draws jar | |
| Yisi et al. | RETRACTED: Extraction of polysaccharide from lotus leaf and its anticancer effect | |
| CN104297441B (en) | The application of the online quality monitoring hierarchy of control of a kind of infrared spectrum in Mongolian medicinal preparation | |
| CN103371916A (en) | Constant temperature herbal medicine infiltrating machine | |
| CN203203923U (en) | Online detection device of water precipitation process of traditional Chinese medicine | |
| CN103977108A (en) | Extraction method of Rosa laevigata Michaux pericarp triterpenoid saponin | |
| CN203556300U (en) | Device for simulating oral dissolution of oral product | |
| CN206152395U (en) | Traditional chinese medicine draws, concentrated jar with near -infrared on -line measuring function | |
| CN209182128U (en) | It is a kind of for there is the sample processing device of adsorptivity matrix | |
| CN202497458U (en) | Constant-temperature herbal medicine infiltrating machine | |
| CN204293887U (en) | A kind of Pharmaceutical Analysis liquefaction evaporating integrated machine | |
| CN202710342U (en) | Reaction kettle sampling device | |
| CN203846006U (en) | Volatile oil extracting, collecting and separating equipment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20150304 |