CN203414406U - Online ultraviolet spectrum detection system in traditional Chinese medicine extraction process - Google Patents
Online ultraviolet spectrum detection system in traditional Chinese medicine extraction process Download PDFInfo
- Publication number
- CN203414406U CN203414406U CN201320490161.4U CN201320490161U CN203414406U CN 203414406 U CN203414406 U CN 203414406U CN 201320490161 U CN201320490161 U CN 201320490161U CN 203414406 U CN203414406 U CN 203414406U
- Authority
- CN
- China
- Prior art keywords
- solenoid valve
- valve
- chinese medicine
- traditional chinese
- detection system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn - After Issue
Links
Images
Landscapes
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
The utility model discloses an online ultraviolet spectrum detection system in a traditional Chinese medicine extraction process. The detection system comprises four parts including an automatic sampling device, a spectrum measuring device, a control system, a data transmission and remote monitoring device; the automatic sampling device is connected with a traditional Chinese medicine extraction circulation pipeline; the spectrum measuring device and the control system are both connected with the automatic sampling device; the data transmission and remote monitoring device is respectively connected with the spectrum measuring device and the control system. According to the online ultraviolet spectrum detection system disclosed by the utility model, the functions of automatic sampling, automatic matching and diluting, automatic spectrum acquisition, automatic cleaning and the like of a traditional Chinese medicine extracting solution are achieved.
Description
Technical field
The utility model relates to the online ultraviolet spectrum detection system of fluid sample in a kind of production run, relates in particular to a kind of online ultraviolet spectrum detection system for the qualitative discriminating of effective constituent in Chinese crude drug leaching process.
Background technology
Modern Chinese herbal medicine production run is by a series of unit operationss, as extracted, the composition such as concentrated, purifying, granulation, dressing, wherein the extraction of effective constituent is one of key link of Chinese medicine production, and advanced extraction process and quality control method are extremely important to curative effect and the stability of raising tcm product quality, enhancing Chinese medicine.At present the conventional control parameter of Chinese medicine extracting tank is mainly contained to pressure, temperature, extraction time etc.
Yet, only rely on the control of these technological parameters can not guarantee the quality of product completely, when the physical attribute of the quality between medicinal material batch when feeding intake there are differences, can cause the problems such as product quality variance is large, poor stability.By the variation of effective constituent in real-time Detection and Extraction process, can provide foundation for the adjusting of production process technology parameter, reduce as far as possible or avoid the problems referred to above.
At present, for the detection of effective constituent in extraction of traditional Chinese medicine mostly by carry out off-line analysis after timing sampling in laboratory, the data that obtain are only relevant with this moment medicinal material effective constituent of this batch, and result has larger hysteresis quality, cannot realize the real-time control to leaching process.
Conventional Effective Component of Chinese Medicine detection method mainly comprises high performance liquid chromatography (HPLC) and spectroscopic methodology, although HPLC analyzes accurately, sample pretreatment is complicated, analysis time long (approximately 30 min), and analyst's workload is large, is difficult to realize on-line analysis.Spectroscopic methodology (comprising infrared spectrum, near infrared spectrum and ultraviolet spectrum etc.) have analysis speed fast, can realize the advantages such as on-line analysis.For extraction of traditional Chinese medicine, infrared spectrum is subject to the interference of water and alcohols solvent, is also difficult to obtain effect; Equally, because the concentration for water and alcohols solvent of the effective ingredient in extract is very low, corresponding near infrared spectrum changes not remarkable.But this does not absorb at UV spectrum segment base for water and alcohols, and ultraviolet spectrum mainly reflects the variation of Chinese medicine ultraviolet active component in extract, is suitable for water extraction and alcohol extracting equipment simultaneously, can obtain online reliable and stable spectrogram; In addition, ultraviolet spectrum changes very sensitive to extract composition.Can say the online test method that ultraviolet spectroscopy is best suited for.
For this reason, domestic utility model patent (application number: the online ultraviolet spectrum detection system that 200710063804.6) has proposed a kind of pharmacy procedure Chinese traditional medicine composition.This system is mainly used in UV-quantitative analysis, need to be equipped with reference liquid, cleaning fluid, titer, dilution etc., in the mode of peristaltic pump group, testing sample is diluted and mix.For guaranteeing the accurate of dilution ratio, before each detection, all needing peristaltic pump discharge characteristic to calibrate; In addition, what this system adopted is the continuous detecting process of carrying out in sample transmission, and result causes sample to flow into continually in waste liquid pool, causes product loss and environmental pollution.
Summary of the invention
The purpose of this utility model is in order to overcome now methodical limitation, provides a kind of new extraction of traditional Chinese medicine online ultraviolet spectrum detection system.The utility model is even by extract being pressed to set dilution proportion, and can change extension rate according to the difference of extract, realizes the real-time monitoring to effective constituent in extraction of traditional Chinese medicine.
The purpose of this utility model is achieved through the following technical solutions: the online ultraviolet spectrum detection system of a kind of extraction of traditional Chinese medicine, comprise: automatic sampling device, spectral measurement device, control system, data transmission and four parts of long-distance monitorng device, automatic sampling device is connected with traditional Chinese medicine extraction circulation line, spectral measurement device is all connected with automatic sampling device with control system, and data transmission is connected with control system with spectral measurement device respectively with long-distance monitorng device;
Further, described automatic sampling device is mainly comprised of extractor circulation line, bypass hand valve, refrigeratory inlet temperature sensor, sample introduction hand valve, hydrocooler, cooler outlet temperature sensor, solenoid valve for sampling, setting-out solenoid valve, sample quantity tube, emptying solenoid valve, counter sample solenoid valve, counter sample hand valve, water inlet pipeline, entering water electromagnetic valve, water Measuring glass, drain solenoid valve, mixing sampling pool, stirring motor, paddle, form, UV fiber, blowoff electromagnetic valve and blow-off line; In extractor circulation line, hand valve is installed, bypass is connected to form circulation line with refrigeratory inlet temperature sensor, sample introduction hand valve, hydrocooler, cooler outlet temperature sensor, solenoid valve for sampling, sample quantity tube, counter sample solenoid valve, counter sample hand valve successively, wherein, sample quantity tube upper and lower side is connected with setting-out solenoid valve with emptying solenoid valve respectively in addition; Water inlet pipeline is connected with entering water electromagnetic valve, water Measuring glass, drain solenoid valve, mixing sampling pool, blowoff electromagnetic valve successively; Mix sampling pool top and be connected with setting-out solenoid valve, two bottom sides has form, and stirring motor is connected with paddle and stretches into and mix sampling pool inside; Blow-off line is connected with water Measuring glass run-down pipe with blowoff electromagnetic valve respectively.
Further, described spectral measurement device comprises: light source, UV fiber, form and ultraviolet spectrometer (UVS); Described light source is directly subject to the control of ultraviolet spectrometer (UVS); Light source is connected with UV fiber, form, ultraviolet spectrometer (UVS) successively.
Further, described control system adopts PLC, comprising: PLC main frame, temperature-measuring module and solenoid valve group and motor drive module; Described PLC main frame is connected with solenoid valve group and motor drive module with temperature-measuring module respectively; Temperature-measuring module is connected with refrigeratory inlet temperature sensor, cooler outlet temperature sensor; Solenoid valve group and motor drive module are connected with stirring motor with whole solenoid valves.
Further, described data transmission and long-distance monitorng device mainly comprise: digital communication module, twisted-pair feeder, supervisory control comuter.Supervisory control comuter is connected with digital communication module by twisted-pair feeder; Digital communication module is connected with ultraviolet spectrometer (UVS), PLC main frame respectively.
The beneficial effects of the utility model are: the utility model is by the online ultraviolet spectrum detection system of a kind of simple, reliable, economic extraction of traditional Chinese medicine, have realized automatic sampling to Chinese medicine extract, automatic mixing dilution, automatic acquisition spectrum, the function such as cleaning automatically; And can be by analyzing the variation of spectrogram in leaching process, the general morphologictrend that Detection and Extraction liquid forms in real time, for operating personnel carry out technological parameter adjusting, endpoint provides important foundation.
Accompanying drawing explanation
Fig. 1 is the general structure schematic diagram of the utility model extraction of traditional Chinese medicine on-line detecting system;
In figure, extractor circulation line 1, bypass hand valve 2, refrigeratory inlet temperature sensor 3, sample introduction hand valve 4, hydrocooler 5, cooler outlet temperature sensor 6, solenoid valve for sampling 7, setting-out solenoid valve 8, sample quantity tube 9, emptying solenoid valve 10, counter sample solenoid valve 11, counter sample hand valve 12, water inlet pipeline 13, entering water electromagnetic valve 14, water Measuring glass 15, water-drainage solenoid valve 16, mix sampling pool 17, stirring motor 18, paddle 19, form 20, UV fiber 21, blowoff electromagnetic valve 22, blow-off line 23, light source 24, spectrometer 25, temperature-measuring module 26, solenoid valve group and motor drive module 27, PLC main frame 28, digital communication module 29, twisted-pair feeder 30, supervisory control comuter 31.
Embodiment
Below in conjunction with drawings and Examples, the utility model is further described.
As shown in Figure 1, the extraction of traditional Chinese medicine ultraviolet spectrum on-line detecting system that the utility model proposes mainly comprises: automatic sampling device, spectral measurement device, PLC control system, data transmission and four parts of long-distance monitorng device.Automatic sampling device is connected with traditional Chinese medicine extraction circulation line, and spectral measurement device is all connected with automatic sampling device with PLC control system, and data transmission is connected with PLC control system with spectral measurement device respectively with long-distance monitorng device.
Automatic sampling device is mainly by extractor circulation line 1, bypass hand valve 2, refrigeratory inlet temperature sensor 3, sample introduction hand valve 4, hydrocooler 5, cooler outlet temperature sensor 6, solenoid valve for sampling 7, setting-out solenoid valve 8, sample quantity tube 9, emptying solenoid valve 10, counter sample solenoid valve 11, counter sample hand valve 12, water inlet pipeline 13, entering water electromagnetic valve 14, water Measuring glass 15, drain solenoid valve 16, mix sampling pool 17, stirring motor 18, paddle 19, form 20, UV fiber 21, blowoff electromagnetic valve 22 and blow-off line 23 form.In extractor circulation line 1 main line, hand valve 2 is installed, bypass is connected to form circulation line with refrigeratory inlet temperature sensor 3, sample introduction hand valve 4, hydrocooler 5, cooler outlet temperature sensor 6, solenoid valve for sampling 7, sample quantity tube 9, counter sample solenoid valve 11, counter sample hand valve 12 successively, wherein, sample quantity tube 9 upper and lower sides are connected with stock layout solenoid valve 8 with emptying solenoid valve 10 respectively in addition; Water inlet pipeline 13 is connected with entering water electromagnetic valve 14, water Measuring glass 15, drain solenoid valve 16, mixing sampling pool 17, blowoff electromagnetic valve 22 successively; Mix sampling pool 17 tops and be connected with setting-out solenoid valve 8, two bottom sides has form 20, and stirring motor 18 is connected with paddle 19 and stretches into and mix sampling pool 17 inside; Blow-off line 23 is connected with the run-down pipe of water Measuring glass 15 with blowoff electromagnetic valve 22 respectively.
Spectral measurement device mainly comprises: light source 24, UV fiber 21, form 20, ultraviolet spectrometer (UVS) 25.Light source 24 is controlled by ultraviolet spectrometer (UVS) 25 directly; Light source 24 is connected with UV fiber 21, form 20, UV fiber 21, ultraviolet spectrometer (UVS) 25 successively.
PLC control system mainly comprises: PLC main frame 28, temperature-measuring module 26, solenoid valve group and motor drive module 27.PLC main frame 28 is connected with solenoid valve group and motor drive module 27 with temperature-measuring module 26 respectively; Temperature-measuring module 26 is connected with refrigeratory inlet temperature sensor 3, cooler outlet temperature sensor 6; Solenoid valve group and motor drive module 27 are connected with solenoid valve for sampling 7, setting-out solenoid valve 8, counter sample solenoid valve 11, emptying solenoid valve 10, entering water electromagnetic valve 14, water-drainage solenoid valve 16, blowoff electromagnetic valve 22 and stirring motor 18.
Data transmission and long-distance monitorng device mainly comprise: digital communication module 29, twisted-pair feeder 30, supervisory control comuter 31.Supervisory control comuter 31 is connected with digital communication module 29 by twisted-pair feeder 30; Digital communication module 29 is connected with PLC main frame 28 with ultraviolet spectrometer (UVS) 25 respectively.PLC main frame is directly accepted the operated from a distance order of supervisory control comuter 31, realize to each solenoid valve, motor switch and the detection of sample temperature.
Claims (5)
1. the online ultraviolet spectrum detection system of extraction of traditional Chinese medicine, it is characterized in that, comprise automatic sampling device, spectral measurement device, control system, data transmission and four parts of long-distance monitorng device, wherein, described automatic sampling device is connected with traditional Chinese medicine extraction circulation line, spectral measurement device is all connected with automatic sampling device with control system, and data transmission is connected with control system with spectral measurement device respectively with long-distance monitorng device.
2. the online ultraviolet spectrum detection system of extraction of traditional Chinese medicine according to claim 1, it is characterized in that, described automatic sampling device is mainly by extractor circulation line (1), bypass hand valve (2), refrigeratory inlet temperature sensor (3), sample introduction hand valve (4), hydrocooler (5), cooler outlet temperature sensor (6), solenoid valve for sampling (7), setting-out solenoid valve (8), sample quantity tube (9), emptying solenoid valve (10), counter sample solenoid valve (11), counter sample hand valve (12), water inlet pipeline (13), entering water electromagnetic valve (14), water Measuring glass (15), drain solenoid valve (16), mix sampling pool (17), stirring motor (18), paddle (19), form (20), UV fiber (21), blowoff electromagnetic valve (22) and blow-off line (23) form, in extractor circulation line (1) main line, hand valve (2) is installed, bypass is connected to form circulation line with refrigeratory inlet temperature sensor (3), sample introduction hand valve (4), hydrocooler (5), cooler outlet temperature sensor (6), solenoid valve for sampling (7), sample quantity tube (9), counter sample solenoid valve (11), counter sample hand valve (12) successively, wherein, sample quantity tube (9) upper and lower side is connected with stock layout solenoid valve (8) with emptying solenoid valve (10) respectively in addition, water inlet pipeline (13) is connected with sampling pool (17), blowoff electromagnetic valve (22) with entering water electromagnetic valve (14), water Measuring glass (15), drain solenoid valve (16), mixing pit successively, mix sampling pool (17) top and be connected with setting-out solenoid valve (8), two bottom sides has form (20), and stirring motor (18) is connected with paddle (19) and stretches into and mix sampling pool (17) inside, blow-off line (23) is connected with the run-down pipe of water Measuring glass (15) with blowoff electromagnetic valve (22) respectively.
3. the online ultraviolet spectrum detection system of extraction of traditional Chinese medicine according to claim 1, is characterized in that, described spectral measurement device comprises: light source (24), UV fiber (21), form (20) and ultraviolet spectrometer (UVS) (25); Described light source (24) is directly subject to the control of ultraviolet spectrometer (UVS) (25); Light source (24) is connected with UV fiber (21), form (20), UV fiber (21), ultraviolet spectrometer (UVS) (25) successively.
4. the online ultraviolet spectrum detection system of extraction of traditional Chinese medicine according to claim 1, it is characterized in that, described control system adopts PLC(programmable logic control system), comprising: PLC main frame (28), temperature-measuring module (26) and solenoid valve group and motor drive module (27); Described PLC main frame (28) is connected with solenoid valve group and motor drive module (27) with temperature-measuring module (26) respectively; Temperature-measuring module (26) is connected with refrigeratory inlet temperature sensor (3), cooler outlet temperature sensor (6); Solenoid valve group and motor drive module (27) are connected with solenoid valve for sampling (7), setting-out solenoid valve (8), counter sample solenoid valve (11), emptying solenoid valve (10), entering water electromagnetic valve (14), water-drainage solenoid valve (16), blowoff electromagnetic valve (22) and stirring motor (18).
5. the online ultraviolet spectrum detection system of extraction of traditional Chinese medicine according to claim 1, is characterized in that, described data transmission and long-distance monitorng device mainly comprise: digital communication module (29), twisted-pair feeder (30), supervisory control comuter (31); Described supervisory control comuter (31) is connected with digital communication module (29) by twisted-pair feeder (30); Digital communication module (29) is connected with PLC main frame (28) with ultraviolet spectrometer (UVS) (25) respectively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320490161.4U CN203414406U (en) | 2013-08-13 | 2013-08-13 | Online ultraviolet spectrum detection system in traditional Chinese medicine extraction process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201320490161.4U CN203414406U (en) | 2013-08-13 | 2013-08-13 | Online ultraviolet spectrum detection system in traditional Chinese medicine extraction process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN203414406U true CN203414406U (en) | 2014-01-29 |
Family
ID=49977288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201320490161.4U Withdrawn - After Issue CN203414406U (en) | 2013-08-13 | 2013-08-13 | Online ultraviolet spectrum detection system in traditional Chinese medicine extraction process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN203414406U (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103411910A (en) * | 2013-08-13 | 2013-11-27 | 杭州派析光电科技有限公司 | On-line ultraviolet spectrum detection method and system for traditional Chinese medicine extraction process |
| CN104122221A (en) * | 2014-08-03 | 2014-10-29 | 北京康仁堂药业有限公司 | On-line ultraviolet analysis method for dynamic tendency during extraction process of traditional Chinese medicines |
| CN104390926A (en) * | 2014-11-04 | 2015-03-04 | 浙江大学 | Online rapid detection method of herba andrographis concentrated decolorization process |
| CN104535519A (en) * | 2014-12-12 | 2015-04-22 | 东北石油大学 | Online detection device for concentration of polyacrylamide in oilfield wastewater |
| CN105717067A (en) * | 2016-05-03 | 2016-06-29 | 哈尔滨珍宝制药有限公司 | Automatic control system for pseudo-ginseng quantitative extraction and method |
| CN112552359A (en) * | 2020-12-21 | 2021-03-26 | 北京大学 | Automatic preparation method of fondaparinux sodium pentasaccharide intermediate |
-
2013
- 2013-08-13 CN CN201320490161.4U patent/CN203414406U/en not_active Withdrawn - After Issue
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103411910A (en) * | 2013-08-13 | 2013-11-27 | 杭州派析光电科技有限公司 | On-line ultraviolet spectrum detection method and system for traditional Chinese medicine extraction process |
| CN104122221A (en) * | 2014-08-03 | 2014-10-29 | 北京康仁堂药业有限公司 | On-line ultraviolet analysis method for dynamic tendency during extraction process of traditional Chinese medicines |
| CN104122221B (en) * | 2014-08-03 | 2016-04-20 | 北京康仁堂药业有限公司 | The online ultra-violet analysis method of extraction of traditional Chinese medicine dynamic trend |
| CN104390926A (en) * | 2014-11-04 | 2015-03-04 | 浙江大学 | Online rapid detection method of herba andrographis concentrated decolorization process |
| CN104535519A (en) * | 2014-12-12 | 2015-04-22 | 东北石油大学 | Online detection device for concentration of polyacrylamide in oilfield wastewater |
| CN105717067A (en) * | 2016-05-03 | 2016-06-29 | 哈尔滨珍宝制药有限公司 | Automatic control system for pseudo-ginseng quantitative extraction and method |
| CN105717067B (en) * | 2016-05-03 | 2019-01-04 | 哈尔滨珍宝制药有限公司 | The automatic control system and method that Radix Notoginseng is quantitatively extracted |
| CN112552359A (en) * | 2020-12-21 | 2021-03-26 | 北京大学 | Automatic preparation method of fondaparinux sodium pentasaccharide intermediate |
| WO2022135319A1 (en) * | 2020-12-21 | 2022-06-30 | 北京大学 | Method for automatic preparation of fondaparinux sodium pentosaccharide intermediate |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103411910B (en) | The online ultraviolet spectrum detection method of extraction of traditional Chinese medicine and system | |
| CN203414406U (en) | Online ultraviolet spectrum detection system in traditional Chinese medicine extraction process | |
| CN207114423U (en) | A kind of Chinese medicine extracts online ultraviolet spectral analysis device | |
| CN203203920U (en) | Online detection device of extraction process of traditional Chinese medicine | |
| CN103913433B (en) | Online detection method for double-effect concentration process of danhong injection | |
| CN101984343B (en) | Method of discriminating key points in macroporous resin separation and purification process of traditional Chinese medicines | |
| CN102262087B (en) | On-line monitoring device for total arsenic in water quality | |
| CN104122221B (en) | The online ultra-violet analysis method of extraction of traditional Chinese medicine dynamic trend | |
| CN102038757B (en) | Quality inspection and control system for medicinal compositions | |
| CN103290640A (en) | On-line detection device and on-line detection method of dye concentration in printing and dyeing process of connecting vat | |
| CN102200507A (en) | Preprocessing system for near-infrared online detection and application thereof | |
| CN102650590A (en) | Method for determining content of nitrogen in nitrate and/or nitrite of water sample and device thereof | |
| CN104406836A (en) | Traditional Chinese medicine extraction process online analysis sample preprocessing apparatus | |
| CN105319175B (en) | The ONLINE RECOGNITION of extraction of traditional Chinese medicine dynamic response model and terminal point determining method | |
| CN104390926B (en) | Online rapid detection method of herba andrographis concentrated decolorization process | |
| CN101664495A (en) | On-line detection method of near infrared spectrum for production process of traditional Chinese medicine, pill of six ingredients with rehmannia | |
| CN109682776A (en) | Multimode near infrared online monitors system and its application method | |
| CN106841057B (en) | A kind of method and apparatus of pre-hydrolysis of biomass process on-line monitoring | |
| CN110346323B (en) | Method for detecting Huagaisan concentrated solution on line based on near infrared spectrum technology | |
| CN104297441B (en) | The application of the online quality monitoring hierarchy of control of a kind of infrared spectrum in Mongolian medicinal preparation | |
| CN101738339B (en) | Near-infrared complete pretreatment device for blended gasoline | |
| CN103749760B (en) | Method and device for controlling moderate fermentation of instant black tea | |
| CN202057604U (en) | On-line monitoring device for total arsenic in water | |
| CN102980789B (en) | Water petroleum pollutant on-line enrichment device | |
| CN106841058A (en) | The online test method and device of a kind of biomass by hydro-thermal preprocessing process |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20140129 Effective date of abandoning: 20150909 |
|
| RGAV | Abandon patent right to avoid regrant |