CN203778184U - Mechanical magnetic separation pen - Google Patents

Mechanical magnetic separation pen Download PDF

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Publication number
CN203778184U
CN203778184U CN201420180851.4U CN201420180851U CN203778184U CN 203778184 U CN203778184 U CN 203778184U CN 201420180851 U CN201420180851 U CN 201420180851U CN 203778184 U CN203778184 U CN 203778184U
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CN
China
Prior art keywords
shaft
writing brush
pen
inner tube
mechanical type
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn - After Issue
Application number
CN201420180851.4U
Other languages
Chinese (zh)
Inventor
杜德光
刘占峰
齐存森
姚玉涛
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luoyang Hui Er Nanosecond Science And Technology Co Ltd
Original Assignee
Luoyang Hui Er Nanosecond Science And Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by Luoyang Hui Er Nanosecond Science And Technology Co Ltd filed Critical Luoyang Hui Er Nanosecond Science And Technology Co Ltd
Priority to CN201420180851.4U priority Critical patent/CN203778184U/en
Application granted granted Critical
Publication of CN203778184U publication Critical patent/CN203778184U/en
Anticipated expiration legal-status Critical
Withdrawn - After Issue legal-status Critical Current

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Abstract

The utility model discloses a mechanical magnetic separation pen. A pressing button is arranged at the upper part of a pen tube; a cartridge is arranged inside the pen tube; a permanent magnet pen point is arranged at the lower part of the cartridge; an operating lever is arranged on a columnar lug boss at the top of the cartridge, and extends out from a lock locating hole formed in the upper part of the pen tube; the lock locating hole comprises a vertical bar hole A formed along the length direction of the pen tube; a transverse bar hole extends at the lower end of the vertical hole along the peripheral direction of the pen tube; an annular lug boss is arranged on the outer wall of the upper part of the cartridge; the cartridge at the lower part of the lug boss is sleeved with a spring; an inner tube is arranged inside the pen tube; a vertical bar hole B is formed in the inner tube along the length direction of the inner tube, and corresponds to the vertical bar hole A; arc pressure plates are symmetrically arranged at the lower end of the inner tube; symmetrical arc holes corresponding to the arc pressure plates are formed in the bottom surface of the pen tube; the lower part of the pen tube is sleeved with an isolation cover. The mechanical magnetic separation pen is convenient to install and dismantle, good in magnetic bead adsorption effect, and quick to switch in the extraction process, and cross contamination is completely eradicated.

Description

A kind of mechanical type Magnetic Isolation pen
Technical field
The utility model belongs to bioseparation technology field, especially relates to a kind of mechanical type Magnetic Isolation pen.
Background technology
Magnetic separation technique is efficient because having, fast, integrate the key areas that the plurality of advantages such as separation and concentration are widely used in the life sciences such as immunoassay, nucleic acid extraction, gene sequencing, cell separation, immobilised enzymes, chiral separation.Compare as the precipitation method, centrifugal process, ion-exchange and various chromatography methods with conventional separation method, that magnetic separation technique has is convenient and swift, equipment needed thereby simple, extraction efficiency high.The roughly process that magnetic separates is to join in the solution that contains sample to be separated in conjunction with the magnetic material of sample to be separated, after magnetic material and the abundant combination of sample to be separated, by magnetic separating apparatus, solution is applied to external magnetic field, the magnetic material that is combined with sample separation under the effect of outside magnetic field from solution enrichment out, thereby realize the separation of sample separation.
At present, conventional magnetic liquid separating tool is mainly magnetic separator frame, is made up of main frame and magnetic sheet, has centrifuge tube hole on main frame, the magnet of embedding some in magnetic sheet.When use, the centrifuge tube that sample is housed is put into hole, the magnetic material in sample can be enriched on the centrifugal tube wall of magnetic sheet one side under magnetic fields, utilizes pipettor to siphon away liquid can to realize the separation of magnetic material.
But existing magnetic separator frame exists following problem in the time of application: 1, volume is large, assembling is complicated, and heaviness, is unfavorable for carrying; 2, in separation process, a little less than magnetic, magnetic disengaging time is long, separates not thorough; 3, sample cell can not tightly be affixed on magnetic sheet face, has a strong impact on separating effect; 4, magnetic material is attracted to the whole sidewall of centrifuge tube in use, while making pipettor imbitition, easily by a magnetic material sucking-off part, causes sample content to reduce, waste, and has also caused experimental error simultaneously.
Summary of the invention
For addressing the above problem, the purpose of this utility model is to provide a kind of reasonable in design, is easy to carry, easy to use, simple to operate, mechanical type Magnetic Isolation pen efficiently.
For achieving the above object, the utility model adopts following technical scheme:
A kind of mechanical type Magnetic Isolation pen, it comprises the shaft of a writing brush, pen core, nib, action bars, press button and transparent separation sleeve, press button and be arranged on shaft of a writing brush top, shaft of a writing brush bottom has the tube shape bulge coaxial with shaft of a writing brush center, pen core is arranged on shaft of a writing brush inside, nib is cylindrical permanent magnet, permanent magnet is arranged on pen core bottom, stretch out outside the shaft of a writing brush permanent magnet lower end, action bars is arranged in the cylindrical boss at pen core top and is vertical with pen core, shaft of a writing brush top offers the locking positioning hole of action bars, action bars stretches out from locking positioning hole, locking positioning hole comprises the vertical bar hole A moving up and down for action bars offering along shaft of a writing brush length direction, vertical core lower end edge shaft of a writing brush circumferencial direction is extended with horizontal bar hole, in pen core external wall of upper portion, there is circular projection, be positioned on the pen core of protruding bottom and be arranged with spring, in the shaft of a writing brush, be provided with an inner tube, in inner tube, offer vertical bar hole B along inner tube length direction, vertically bar hole B is corresponding with the vertical bar hole A on the shaft of a writing brush, outer wall of inner tube and shaft of a writing brush inwall fit, inner tube lower end is symmetrically arranged with arc compressing tablet, shaft of a writing brush bottom surface offers symmetrical arcuate socket, and two arc compressing tablets are corresponding with two arcuate sockets, separation sleeve is sleeved on the tube shape bulge of shaft of a writing brush bottom through upper end enlarging.
Above-mentioned mechanical type Magnetic Isolation pen, its shaft of a writing brush top is provided with a retainer ring, and retainer ring is at inner tube top and the shaft of a writing brush and pressing between button.
Above-mentioned mechanical type Magnetic Isolation pen, the vertical bar hole B width in its inner tube is greater than the vertical bar hole A on the shaft of a writing brush.
Above-mentioned mechanical type Magnetic Isolation pen, its permanent magnet nib adopts axial charging magnet or radial magnetizing magnet.
Above-mentioned mechanical type Magnetic Isolation pen, its action bars outer end is spherical shape.
Above-mentioned mechanical type Magnetic Isolation pen, on its pen core, sheathed spring is monoblock type, or is made up of several little springs.
Above-mentioned mechanical type Magnetic Isolation pen, is provided with a suspender on its shaft of a writing brush outer wall.
Above-mentioned mechanical type Magnetic Isolation pen, it is pressed button, the shaft of a writing brush, inner tube, pen core and action bars material and is ABS.
Above-mentioned mechanical type Magnetic Isolation pen, its separation sleeve material is PC.
Above-mentioned mechanical type Magnetic Isolation pen, its shaft of a writing brush, inner tube lower end all have taper reducing.
Owing to adopting technical scheme as above, the utlity model has following superiority:
This mechanical type Magnetic Isolation pen, it is easy to make, with low cost, be easy to carry, easy installation and removal, make it to be displaced downwardly to the horizontal bar hole in locking positioning hole by pressing operation bar, permanent magnet nib and pen core bottom are stretched in separation sleeve, permanent magnet nib is adsorbed onto the biomagnetic beads in liquid in vitro on separation sleeve, realize magnetic liquid and separate fast, absorption magnetic bead is effective, can in leaching process, switch fast, stop cross pollution, greatly met paramagnetic particle method and extracted flexibility and the practicality in experiment and detection; The circular protruding retainer spring stroke range having in pen core external wall of upper portion; In permanent magnet nib absorption magnetic bead process, inner tube can not exert an influence, and completes after the separation of magnetic liquid, press press button promote inner tube move down, the arc compressing tablet of inner tube lower end stretches out and pushes separation sleeve from the arcuate socket of shaft of a writing brush bottom surface, makes that separation sleeve and the shaft of a writing brush are quick to be separated, and increases work efficiency.
Brief description of the drawings
Fig. 1 is the exploded view of the utility model mechanical type Magnetic Isolation pen;
Fig. 2 is the structural representation of the utility model mechanical type Magnetic Isolation pen;
Fig. 3 is the working state figure A of the utility model mechanical type Magnetic Isolation pen;
Fig. 4 is the working state figure B of the utility model mechanical type Magnetic Isolation pen;
In figure: 1-presses button; 2-inner tube; The vertical bar hole B of 3-; 4-arc compressing tablet; 5-action bars; 6-cylindrical boss; 7-pen core; The circular projection of 8-; 9-spring; 10-permanent magnet; 11-suspender; The vertical bar hole A of 12-; The horizontal bar hole of 13-; The 14-shaft of a writing brush; 15-tube shape bulge; 16-enlarging; 17-separation sleeve; 18-taper lower end.
Detailed description of the invention
Below in conjunction with drawings and Examples, the technical solution of the utility model is described in further detail.
As Fig. 1, shown in 2, this mechanical type Magnetic Isolation pen, it comprises the shaft of a writing brush 14, pen core 7, nib, action bars 5, press button 1 and transparent separation sleeve 17, press button 1 and be arranged on the shaft of a writing brush 14 tops, shaft of a writing brush bottom has the tube shape bulge 15 coaxial with shaft of a writing brush center, pen core 7 is arranged on shaft of a writing brush inside, nib is cylindrical permanent magnet 10, permanent magnet is arranged on pen core bottom, stretch out outside the shaft of a writing brush permanent magnet lower end, action bars 5 is arranged in the cylindrical boss 6 at pen core top and is vertical with pen core, shaft of a writing brush top offers the locking positioning hole of action bars, action bars stretches out from locking positioning hole, locking positioning hole comprises the vertical bar hole A 12 moving up and down for action bars offering along shaft of a writing brush length direction, vertical core lower end edge shaft of a writing brush circumferencial direction is extended with horizontal bar hole 13, in pen core 7 external wall of upper portion, have circular protruding 8, be positioned on the pen core of this protruding bottom and be arranged with spring 9, in the shaft of a writing brush, be provided with an inner tube 2, in inner tube, offer vertical bar hole B 3 along inner tube length direction, vertically bar hole B is corresponding with the vertical bar hole A on the shaft of a writing brush, vertical bar hole B width in inner tube is greater than the vertical bar hole A on the shaft of a writing brush, outer wall of inner tube and shaft of a writing brush inwall fit, inner tube lower end is symmetrically arranged with arc compressing tablet 4, and shaft of a writing brush bottom surface offers symmetrical arcuate socket, and two arc compressing tablets are corresponding with two arcuate sockets, straight tube, lower end that separation sleeve 17 is upper end open are taper, and upper end enlarging 16 is sleeved on the tube shape bulge 15 of shaft of a writing brush bottom.
Above-mentioned shaft of a writing brush top is provided with a retainer ring, and retainer ring is at inner tube top and the shaft of a writing brush and pressing between button.Retainer ring can prevent that inner tube from upspringing in the shaft of a writing brush.
Above-mentioned permanent magnet nib adopts axial charging magnet or radial magnetizing magnet.
Above-mentioned action bars outer end is spherical shape, and convenient operation personnel carry out pressing operation, safe and reliable.
On above-mentioned pen core, sheathed spring is monoblock type, or is made up of several little springs.Spring is covered with the pen core of protruding bottom.
On above-mentioned shaft of a writing brush outer wall, be provided with a suspender 11, be convenient to the suspension of Magnetic Isolation pen and lay.
Above-mentioned mechanical type Magnetic Isolation pen, it is pressed button, the shaft of a writing brush, inner tube, pen core and action bars material and is ABS.
Above-mentioned mechanical type Magnetic Isolation pen, its separation sleeve material is PC.
Above-mentioned mechanical type Magnetic Isolation pen, its shaft of a writing brush, inner tube lower end all have taper reducing.
While using mechanical type Magnetic Isolation pen to carry out the separation of magnetic liquid to the liquid in test tube, the separation sleeve 17 of the shaft of a writing brush 14 bottoms is stretched in test tube, the taper lower end 18 of separation sleeve is positioned under liquid level, pressing operation bar 5 makes it to move down and enter positioning and locking in Cross slat shape hole 13 along vertical bar hole A 12, action bars moves down and drives pen core 7 to move down permanent magnet nib, pen core bottom are stretched in separation sleeve, biomagnetic beads in permanent magnet nib adsorptive liquid is to the taper lower end of separation sleeve, as shown in Figure 3; Then mechanical type Magnetic Isolation pen is moved in the test tube that need to discharge biomagnetic beads, action bars is moved to initial position along opposite direction, permanent magnet nib also restPoses, the absorption affinity that loses magnetism makes biomagnetic beads depart from from separation sleeve, fall into test tube, as shown in Figure 2, after mechanical type Magnetic Isolation pen is finished using, press and press button 1, pressing button promotion inner tube 2 moves down, the arc compressing tablet 4 of inner tube lower end stretches out extruding separation sleeve from the arcuate socket of shaft of a writing brush bottom surface, separation sleeve is come off, as shown in Figure 4 from the shaft of a writing brush.Used separation sleeve is abandoned, new separation sleeve is installed on the shaft of a writing brush, can carry out magnetic liquid next time and separate.

Claims (10)

1. a mechanical type Magnetic Isolation pen, comprise the shaft of a writing brush, pen core, nib, action bars, press button and separation sleeve, press button and be arranged on shaft of a writing brush top, shaft of a writing brush bottom has the tube shape bulge coaxial with shaft of a writing brush center, pen core is arranged on shaft of a writing brush inside, nib is cylindrical permanent magnet, permanent magnet is arranged on pen core bottom, stretch out outside the shaft of a writing brush permanent magnet lower end, action bars is arranged in the cylindrical boss at pen core top and is vertical with pen core, shaft of a writing brush top offers the locking positioning hole of action bars, action bars stretches out from locking positioning hole, locking positioning hole comprises the vertical bar hole A moving up and down for action bars offering along shaft of a writing brush length direction, vertical core lower end edge shaft of a writing brush circumferencial direction is extended with horizontal bar hole, it is characterized in that: in its pen core (7) external wall of upper portion, there is circular projection (8), be positioned on the pen core of protruding bottom and be arranged with spring (9), in the shaft of a writing brush (14), be provided with an inner tube (2), in inner tube, offer vertical bar hole B(3 along inner tube length direction), vertically bar hole B and vertical bar hole A(12 on the shaft of a writing brush) corresponding, outer wall of inner tube and shaft of a writing brush inwall fit, inner tube lower end is symmetrically arranged with arc compressing tablet (4), shaft of a writing brush bottom surface offers symmetrical arcuate socket, and two arc compressing tablets are corresponding with two arcuate sockets, transparent separation sleeve (17) is sleeved on the tube shape bulge (15) of shaft of a writing brush bottom through upper end enlarging.
2. mechanical type Magnetic Isolation pen according to claim 1, is characterized in that: its shaft of a writing brush top is provided with a retainer ring, and retainer ring is at inner tube top and the shaft of a writing brush and pressing between button.
3. mechanical type Magnetic Isolation pen according to claim 1, is characterized in that: the vertical bar hole B width in its inner tube is greater than the vertical bar hole A on the shaft of a writing brush.
4. mechanical type Magnetic Isolation pen according to claim 1, is characterized in that: its permanent magnet nib adopts axial charging magnet or radial magnetizing magnet.
5. mechanical type Magnetic Isolation pen according to claim 1, is characterized in that: its action bars outer end is spherical shape.
6. mechanical type Magnetic Isolation pen according to claim 1, is characterized in that: on its pen core, sheathed spring is monoblock type, or is made up of several little springs.
7. mechanical type Magnetic Isolation pen according to claim 1, is characterized in that: on its shaft of a writing brush (14) outer wall, be provided with a suspender (11).
8. mechanical type Magnetic Isolation pen according to claim 1, is characterized in that: it is pressed button, the shaft of a writing brush, inner tube, pen core and action bars material and is ABS.
9. mechanical type Magnetic Isolation pen according to claim 1, is characterized in that: its separation sleeve material is PC.
10. mechanical type Magnetic Isolation pen according to claim 1, is characterized in that: its shaft of a writing brush, inner tube lower end all have taper reducing.
CN201420180851.4U 2014-04-15 2014-04-15 Mechanical magnetic separation pen Withdrawn - After Issue CN203778184U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201420180851.4U CN203778184U (en) 2014-04-15 2014-04-15 Mechanical magnetic separation pen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201420180851.4U CN203778184U (en) 2014-04-15 2014-04-15 Mechanical magnetic separation pen

Publications (1)

Publication Number Publication Date
CN203778184U true CN203778184U (en) 2014-08-20

Family

ID=51314413

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201420180851.4U Withdrawn - After Issue CN203778184U (en) 2014-04-15 2014-04-15 Mechanical magnetic separation pen

Country Status (1)

Country Link
CN (1) CN203778184U (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103909010A (en) * 2014-04-15 2014-07-09 洛阳惠尔纳米科技有限公司 Mechanical type magnetic separation pen
CN104208906A (en) * 2014-09-03 2014-12-17 上海市刑事科学技术研究院 Simple and easy collection and elution device for magnetic nano enriching material and application method of simple and easy collection and elution device
CN106198696A (en) * 2016-07-04 2016-12-07 太原理工大学 Portable trace heavy metal ion Concentration Testing pen

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103909010A (en) * 2014-04-15 2014-07-09 洛阳惠尔纳米科技有限公司 Mechanical type magnetic separation pen
CN104208906A (en) * 2014-09-03 2014-12-17 上海市刑事科学技术研究院 Simple and easy collection and elution device for magnetic nano enriching material and application method of simple and easy collection and elution device
CN106198696A (en) * 2016-07-04 2016-12-07 太原理工大学 Portable trace heavy metal ion Concentration Testing pen
CN106198696B (en) * 2016-07-04 2018-04-24 太原理工大学 Portable trace heavy metal ion Concentration Testing pen

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Legal Events

Date Code Title Description
C14 Grant of patent or utility model
GR01 Patent grant
AV01 Patent right actively abandoned

Granted publication date: 20140820

Effective date of abandoning: 20160504

C25 Abandonment of patent right or utility model to avoid double patenting