CN102494921A - Trace magnetic particle sampler - Google Patents
Trace magnetic particle sampler Download PDFInfo
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- CN102494921A CN102494921A CN2011103918914A CN201110391891A CN102494921A CN 102494921 A CN102494921 A CN 102494921A CN 2011103918914 A CN2011103918914 A CN 2011103918914A CN 201110391891 A CN201110391891 A CN 201110391891A CN 102494921 A CN102494921 A CN 102494921A
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Abstract
The invention discloses a trace magnetic particle sampler, comprising a pressing cap (1), a ratchet wheel structure (2), a shell (3), a column core (4), a spring (5), a permanent magnet block (6) and an outer sleeve (7). The trace magnetic particle sampler is characterized in that: the pressing cap (1) is installed on the ratchet wheel structure (2) and is clamped in the shell (3); the column core (4) is tightly installed below the ratchet wheel structure (2) and the spring (5) is clamped on the column core (4) and the shell (3); the permanent magnet block (6) is tightly connected with the column core (4) through a groove type structure and the outer sleeve (7) is tightly connected below the shell (3). The trace magnetic particle sampler has the beneficial effects that: the trace magnetic particle sampler has the advantages of small volume, fastness and convenience for operation and the like; and some defects in an existing operation method are better improved, so that the realization of rapidly and conveniently obtaining trace magnetic particles is simple, convenient and fast.
Description
Technical field
The invention belongs to micro-magnetic particle and pipette device, particularly be applied to laboratory trace magnetic particle ST.
Background technology
The magnetic particle has a lot of particular performances; Thereby be widely used in fields such as chemical industry, metallurgy, biotechnology and biomedicine; As can be used as magnetic fluid, magnetic recording material, catalyzer or catalyst support; Microwave absorbing material, and field such as cell separation, immune detection, protein purification, separate nucleic acid, targeted drug, immobilised enzymes.
Yet the widespread use of magnetic particle is to be based upon on the basis that micro-scale testing achieves success, and in order to study the special performance of magnetic particle better, the sampling of micro-magnetic particle pipettes the obvious more and more important effect of bringing into play.
Two kinds of main micro-magnetic particles pipette sampling method at present, and the one, filtration method, another is the magnet absorption method.Filtration method is mainly used sand formula funnel, use filter paper, and part magnetic particle is stood on the paper, a loss part; Though and the magnet absorption method is without paper, complex operation.
Summary of the invention
The present invention is directed to the deficiency of above-mentioned prior art, provide that a kind of to have a volume little, the micro-magnetic particle ST of advantage such as swift and convenient to operate.
Technical scheme of the present invention is: micro-magnetic particle ST, comprise pressure cap 1, ratchet structure 2, shell 3, the post heart 4, spring 5, permanent magnetic iron block 6, overcoat 7, and it is characterized in that: pressure cap 1 is installed on the ratchet structure 2, and is stuck in the shell 3; The post heart 4 snugly fits into the below of ratchet structure 2, and spring 5 is stuck on the post heart 4 and the shell 3; Permanent magnetic iron block 6 closely is connected on the post heart 4 through trench structure, and overcoat 7 closely is connected shell 3 belows.
Said micro-magnetic particle ST ratchet structure 2 comprise on the button with button under two parts.
On the said micro-magnetic particle ST shell 3: a section is the space of ratchet structure motion, has a circumferential step to block the location; The b section is the move distance of pressure cap 1, also has a circumferential step to block the location: the c section is the length of three guiding ribs, the distance of c section and f section and the distance that is the b section; The e section is for breaking away from the position of rib by the strong rib of arrival down least significant end.
The permanent magnetic iron block 6 of said micro-magnetic particle ST is vertical permanent magnet, and its length is 1.5～4cm, and width is 2～5mm.
The permanent magnetic iron block 6 of said micro-magnetic particle ST closely links together through the trench structure and the post heart 4, also has adhesive therebetween.
The diameter of said micro-magnetic particle ST overcoat 7 is 5～7mm, and material is a magnetic stainless steel, and its big I guarantees that permanent magnetic iron block can stretch into wherein as required fully.
Beneficial effect of the present invention: the present invention's trace magnetic particle ST; It is little that it has a volume; Advantage such as swift and convenient to operate has been improved some defectives in the existing method of operating preferably, makes that quick and convenient to pipette exactly that micro-magnetic particle is achieved be simple and convenient quick again.
Description of drawings
Fig. 1 faces structural representation for the present invention's trace magnetic particle ST
The accompanying drawing sign: 1 is that pressure cap, 2 is that ratchet structure, 3 is that shell, 4 is that the post heart, 5 is that spring, 6 is that permanent magnetic iron block, 7 is an overcoat.
Embodiment
Below in conjunction with accompanying drawing 1 and embodiment summary of the invention of the present invention is done further to describe.
As shown in Figure 1, the specific embodiment of the invention: micro-magnetic particle ST, comprise pressure cap 1, ratchet structure 2, shell 3, the post heart 4, spring 5, permanent magnetic iron block 6, overcoat 7, it is characterized in that: pressure cap 1 is installed on the ratchet structure 2, and is stuck in the shell 3; The post heart 4 snugly fits into the below of ratchet structure 2, and spring 5 is stuck on the post heart 4 and the shell 3; Permanent magnetic iron block 6 closely is connected on the post heart 4 through trench structure, and overcoat 7 closely is connected shell 3 belows.
Said micro-magnetic particle ST ratchet structure 2 comprise on the button with button under two parts.
On the said micro-magnetic particle ST shell 3: a section is the space of ratchet structure motion, has a circumferential step to block the location; The b section is the move distance of pressure cap 1, also has a circumferential step to block the location: the c section is the length of three guiding ribs, the distance of c section and f section and the distance that is the b section; The e section is for breaking away from the position of rib by the strong rib of arrival down least significant end.
The permanent magnetic iron block 6 of said micro-magnetic particle ST is vertical permanent magnet, and its length is 1.5～4cm, and width is 2～5mm.
The permanent magnetic iron block 6 of said micro-magnetic particle ST closely links together through the trench structure and the post heart 4, also has adhesive therebetween.
The diameter of said micro-magnetic particle ST overcoat 7 is 5～7mm, and material is a magnetic stainless steel, and its big I guarantees that permanent magnetic iron block can stretch into wherein as required fully.
Below respectively with get Fe3O4, ZrO2/Fe3O4 compound substance magnetic-particle sample is an example, device provided by the invention is further described, but protection scope of the present invention does not receive the restriction of these embodiment.
Embodiment 1
Use the described micro-magnetic particle ST of present embodiment and get micro Fe 3O4 magnetic-particle, concrete steps are:
(1) configuration concentration is 2%Fe3O4 magnetic particles dispersion system, and wherein the diameter of Fe3O4 magnetic-particle is approximately 1um;
(2) push top pressure cap 1, Nd-Fe-B permanent magnetic iron block 6 gets in the magnetic stainless steel overcoat 7;
(3) it is stretched in the Fe3O4 colloid magnetic particle dispersion system that configures, can realize the absorption of magnetic particle;
(4) it is taken out from dispersed system, stretch in another container, through pushing top pressure cap 1 once more, permanent magnetic iron block 6 is withdrawn in the magnetic stainless steel shell 3, thereby leaves overcoat, the magnetic particle gets in the specified containers, the sampling of magnetic particle success.
Use the described micro-magnetic particle ST of present embodiment and get micro-ZrO2/Fe3O4 magnetic-particle, concrete steps are:
(1) configuration concentration is 1% ZrO2/Fe3O4 magnetic particles dispersion system, and wherein the diameter of ZrO2/Fe3O4 magnetic-particle is approximately 0.2um;
(2) push top pressure cap 1, rubber permanent magnet iron block 6 gets in the magnetic stainless steel overcoat 7;
(3) it is stretched in the ZrO2/Fe3O4 colloid magnetic particle dispersion system that configures, can realize the absorption of magnetic particle;
(4) it is taken out from dispersed system, stretch in another container, through pushing top pressure cap 1 once more, permanent magnetic iron block 6 is withdrawn in the magnetic stainless steel shell 3, thereby leaves overcoat, the magnetic particle gets in the specified containers, the sampling of magnetic particle success.
Embodiment 1 and embodiment 2 are two preferred embodiments of micro-magnetic particle ST provided by the invention, and in fact this device can be used for realizing pipetting of nearly all micro-magnetic particle.In practical application, the material of permanent magnet, size, the material of shell, the material of magnetic stainless steel overcoat and size etc. can be carried out suitable conversion according to different requirement.
Should be appreciated that the above detailed description of technical scheme of the present invention being carried out by preferred embodiment is schematic and nonrestrictive.Those of ordinary skill in the art is reading on the basis of instructions of the present invention and can make amendment to the technical scheme that each instance is put down in writing, and perhaps part technical characterictic wherein is equal to replacement; And these are revised or replacement, do not make the spirit and the scope of the essence disengaging various embodiments of the present invention technical scheme of relevant art scheme.
Claims (6)
1. micro-magnetic particle ST comprises pressure cap (1), ratchet structure (2), shell (3), the post heart (4), spring (5), permanent magnetic iron block (6), overcoat (7), and it is characterized in that: pressure cap (1) is installed on the ratchet structure (2), and is stuck in the shell (3); The post heart (4) snugly fits into the below of ratchet structure (2), and spring (5) is stuck on the post heart (4) and the shell (3); Permanent magnetic iron block (6) closely is connected on the post heart (4) through trench structure, and overcoat (7) closely is connected shell (3) below.
2. micro-magnetic particle ST according to claim 1 is characterized in that: the ratchet structure (2) of said micro-magnetic particle ST comprise on the button with button under two parts.
3. micro-magnetic particle ST according to claim 1 is characterized in that: on the shell (3) of said micro-magnetic particle ST: a section is the space of ratchet structure motion, has a circumferential step to block the location; The b section is the move distance of pressure cap (1), also has a circumferential step to block the location: the c section is the length of three guiding ribs, the distance of c section and f section and the distance that is the b section; The e section is for breaking away from the position of rib by the strong rib of arrival down least significant end.
4. micro-magnetic particle ST according to claim 1 is characterized in that: the permanent magnetic iron block (6) of said micro-magnetic particle ST is vertical permanent magnet, and its length is 1.5～4cm, and width is 2～5mm.
5. micro-magnetic particle ST according to claim 1 is characterized in that: the permanent magnetic iron block (6) of said micro-magnetic particle ST closely links together through the trench structure and the post heart (4), also has adhesive therebetween.
6. micro-magnetic particle ST according to claim 1 is characterized in that: the diameter of the overcoat (7) of said micro-magnetic particle ST is 5～7mm, and material is a magnetic stainless steel, and its big I guarantees that permanent magnetic iron block can stretch into wherein as required fully.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103918914A CN102494921A (en) | 2011-11-30 | 2011-11-30 | Trace magnetic particle sampler |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103918914A CN102494921A (en) | 2011-11-30 | 2011-11-30 | Trace magnetic particle sampler |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102494921A true CN102494921A (en) | 2012-06-13 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011103918914A Pending CN102494921A (en) | 2011-11-30 | 2011-11-30 | Trace magnetic particle sampler |
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| CN (1) | CN102494921A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104646176A (en) * | 2015-02-11 | 2015-05-27 | 英芮诚生化科技（上海）有限公司 | Manual magnetic solid extractor |
| WO2015077980A1 (en) * | 2013-11-29 | 2015-06-04 | 益生生技开发股份有限公司 | Replaceable sampling assembly, and sampling device having same |
| CN105586258A (en) * | 2016-03-14 | 2016-05-18 | 郭亮甫 | Magnetic adsorption transfer bar |
| CN106813944A (en) * | 2017-04-13 | 2017-06-09 | 太平洋水处理工程有限公司 | The sampler and detection method of dense media powder content in a kind of detection water |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0252694A1 (en) * | 1986-07-07 | 1988-01-13 | Parker Pen (Benelux) B.V. | Writing instrument |
| CN2796842Y (en) * | 2005-06-16 | 2006-07-19 | 上海交通大学 | Hand pressing type bio separation magnetic pen |
| CN200945454Y (en) * | 2006-06-16 | 2007-09-12 | 复旦大学 | Portable magnetic separating pen |
-
2011
- 2011-11-30 CN CN2011103918914A patent/CN102494921A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0252694A1 (en) * | 1986-07-07 | 1988-01-13 | Parker Pen (Benelux) B.V. | Writing instrument |
| CN2796842Y (en) * | 2005-06-16 | 2006-07-19 | 上海交通大学 | Hand pressing type bio separation magnetic pen |
| CN200945454Y (en) * | 2006-06-16 | 2007-09-12 | 复旦大学 | Portable magnetic separating pen |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015077980A1 (en) * | 2013-11-29 | 2015-06-04 | 益生生技开发股份有限公司 | Replaceable sampling assembly, and sampling device having same |
| CN104646176A (en) * | 2015-02-11 | 2015-05-27 | 英芮诚生化科技（上海）有限公司 | Manual magnetic solid extractor |
| CN105586258A (en) * | 2016-03-14 | 2016-05-18 | 郭亮甫 | Magnetic adsorption transfer bar |
| CN105586258B (en) * | 2016-03-14 | 2018-08-17 | 佛山市汇广健医疗科技有限公司 | Magnetic absorption transferring stick |
| CN106813944A (en) * | 2017-04-13 | 2017-06-09 | 太平洋水处理工程有限公司 | The sampler and detection method of dense media powder content in a kind of detection water |
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Application publication date: 20120613 |