CN202020800U - Drawer-type local irradiation device for tumor bearing mouse - Google Patents

Drawer-type local irradiation device for tumor bearing mouse Download PDF

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Publication number
CN202020800U
CN202020800U CN2011200920208U CN201120092020U CN202020800U CN 202020800 U CN202020800 U CN 202020800U CN 2011200920208 U CN2011200920208 U CN 2011200920208U CN 201120092020 U CN201120092020 U CN 201120092020U CN 202020800 U CN202020800 U CN 202020800U
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China
Prior art keywords
shell
inner shell
tumor
bearing mice
irradiation device
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Expired - Fee Related
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CN2011200920208U
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Chinese (zh)
Inventor
樊赛军
徐加英
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Suzhou University
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Suzhou University
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Abstract

The utility model discloses a drawer-type local irradiation device for a tumor bearing mouse, which comprises an outer casing and an inner casing. The outer casing is a lead glass box body with an opening at the left end, the inner casing can be inserted from the left end of the outer casing and slid freely inside the casing, and a locating device is arranged between the outer casing and the inner casing. A panel is fixedly arranged on the bottom of the outer side of the left wall of the inner casing, and a fixed column is arranged on the panel. A through hole is arranged on the left wall of the inner casing and used for the tumor bearing mouse to penetrate through. The left wall of the inner casing is hinged with the inner casing and locked with the inner casing through a buckle. The right end of the inner casing is open, and a right wall of the outer casing is provided with at least two air holes. A relative position of the inner casing and the outer casing can be adjusted according to a body shape of the tumor bearing mouse, and the mouse can be fixed tightly during an experiment, thereby improving efficiency and quality of an irradiation experiment.

Description

A kind of drawer type tumor-bearing mice local irradiation device
Technical field
This utility model relates to a kind of radiotherapy device, is specifically related to a kind of drawer type tumor-bearing mice local irradiation device.
Background technology
Malignant tumor is one of important diseases of current harm humans health, is human first killer of new century, and human survival is constituted the most serious threat.Comparatively sophisticated at present Therapeutic Method has operative treatment, radiotherapy, Drug therapy and immunization therapy four classes.In recent years, tumor radiotherapy had been made significant headway, but unsatisfactory to harm humans life and health therapeutic effect the most serious, that account for the solid tumor of malignant tumor more than 90%; And most radiotherapies produce detrimental effect inevitably to normal structure, organ in inhibition or killing tumor cell, bring misery to the patient, even cause death.In concrete process of experimental, normally utilize mice to carry out irradiation experiment, be about to mice and put into wide mouthed bottle or other glass containers, reuse x ray or other rays shine research.
Sometimes need carry out irradiation research to the part of tumor-bearing mice because of experiment, existing method is to twine the radiation protection material band on one's body mice, only will need the position of irradiation to expose.But radiation protection material is often heavier or harder, very trouble operates, do not reach ideal occlusion effect even can come off, mice is wound and agitation may occurs behind the protective material and cause and can't fix in addition, because during irradiation absorbed dose of mice and distance square be inverse ratio, so mice plays very large effect here apart from the distance of radioactive source.But the volume of laboratory mice can be not in full accord, when the volume of mice changes, the inner space of always wishing the mice fixture can fit like a glove with the build of mice, makes the mice can not be free movable in fixture, guarantees the experiment effect of irradiation experiment.
Summary of the invention
Goal of the invention of the present utility model provides a kind of drawer type tumor-bearing mice local irradiation device; improvement by structure; can be under to the situation of tumor-bearing mice local irradiation other positions of protection mice be not subjected to the influence of X ray, and mice is fixed in the radiotherapy process, can not be free movable.
To achieve the above object of the invention, the technical solution adopted in the utility model is: a kind of tumor-bearing mice local irradiation device, comprise a shell, and described shell is the open lead glass box body of left end; Described tumor-bearing mice local irradiation device also comprises an inner shell, and described inner shell can insert from the left end of shell, and can freely twitch in the enclosure; And be provided with positioner between described shell and the inner shell; The left wall exterior bottom of described inner shell is installed with a flat board, and described flat board is provided with a fixed leg; Offer a through hole on the wall of a described inner shell left side, described through hole can pass through for the tumor-bearing mice tumor locus; Described inner shell left side wall and inner shell are articulated and connected, and sealed by hasp and inner shell;
The right-hand member of described inner shell is uncovered, and the right wall of described shell is provided with plural air-vent.
In the technique scheme, described positioner comprises a bolt and a snib groove, and the snib groove is located on the antetheca of shell, bolt passes the snib groove and links to each other with inner shell, when needs fixedly during the position of inner shell and shell, the head of bolt is pressed on the described shell antetheca, can locate.
Optimized technical scheme, the length of described shell is 6.3cm, the length of the box body section of described inner shell is 5.5cm, the wide and high of described shell is 4cm, the wide and high of described inner shell is 3.7cm, described flat board is the rectangular plastic plate of long 3cm, wide 3.7cm, and sized data is all the inventor and sets according to the experiment needs.
In the technique scheme, described inner shell upper end is uncovered, and the material of described inner shell is a common plastics.
In the technique scheme, sponge is laid in the bottom of described inner shell.
In the technique scheme, described through hole is circular, square or arch, and the edge of described through hole is provided with rubber blanket.
In the technique scheme, the material of described inner shell left side wall is a lead glass.
Experiment set-up procedure: at first open the left wall of inner shell, the tumor locus of tumor-bearing mice is pulled out by described through hole, close inner shell left side wall, and utilize hasp and inner shell sealed; The shank that then tumor-bearing mice is stretched out inner shell is fixed on the fixed leg on the flat board; The inner shell that tumor-bearing mice will be housed then pushes shell, and determine that according to the build of tumor-bearing mice inner shell pushes the degree of depth of shell, inserting bolt and screwing in snib groove and screwed hole is completely fixed shell and inner shell at last, begins to carry out the local irradiation experiment of tumor-bearing mice.
Because the technique scheme utilization, this utility model compared with prior art has following advantage:
1. inner shell of the present utility model can freely be twitched in the enclosure, so can adjust the relative position of inner shell and shell according to the build of tumor-bearing mice, and utilize snib that both are completely fixed, tumor-bearing mice can not be free movable in fixture, mice is fixed in the experiment, improves the efficient and the quality of irradiation experiment.
2. shell of the present utility model is made by lead glass, can play good shield effectiveness to the normal position of the tumor-bearing mice that is positioned at inner shell, and other positions of protection mice are not subjected to the influence of X ray under to the situation of tumor-bearing mice local irradiation.
3. this utility model is provided with air-vent, can guarantee the eupnea of tumor-bearing mice in experimentation.
4. this utility model is lined with rubber blanket at the edge of through hole, stops the poor skin of He Liuchu to be scratched because of tractive and friction in the irradiation experiment.
Description of drawings
Fig. 1 is the schematic perspective view of embodiment one described tumor-bearing mice local irradiation device;
Fig. 2 is the front view of embodiment one described tumor-bearing mice local irradiation device;
Fig. 3 is the vertical view of embodiment one described tumor-bearing mice local irradiation device;
Fig. 4 is the left view of embodiment one described tumor-bearing mice local irradiation device;
Fig. 5 is the right view of embodiment one described tumor-bearing mice local irradiation device;
Fig. 6 is the cutaway view of A-A along the line among Fig. 1;
Fig. 7 is the front view of the inner shell of embodiment one described tumor-bearing mice local irradiation device;
Fig. 8 is the left view of the inner shell of embodiment one described tumor-bearing mice local irradiation device;
Fig. 9 is the front view of the shell of embodiment one described tumor-bearing mice local irradiation device;
Figure 10 is the left view of the shell of embodiment one described tumor-bearing mice local irradiation device;
Wherein: 1, shell; 2, inner shell; 3, inner shell left side wall; 4, shell antetheca; 5, inner shell antetheca; 6, hasp; 7, through hole; 8, tumor locus; 9, flat board; 10, fixed leg; 11, the right wall of shell; 12, air-vent; 13, snib groove; 14, screwed hole; 15, bolt; 16, sponge; 17, rubber blanket.
The specific embodiment
Below in conjunction with drawings and Examples this utility model is further described:
Embodiment one: shown in Fig. 1~6, a kind of tumor-bearing mice local irradiation device comprises a shell 1, and described shell 1 is the open box body of left end, and material is a lead glass; Described tumor-bearing mice local irradiation device also comprises an inner shell 2, and described inner shell 2 can insert from the left end of this shell 1, and can freely twitch in shell 1; Simultaneously, the antetheca 4 of described shell is provided with snib groove 13, the antetheca 5 of described inner shell is provided with screwed hole 14, bolt 15 passes described snib groove 13 and screws with described screwed hole 14, and bolt head is pressed on the described shell antetheca 4, described shell 1 and inner shell 2 are tightened the realization relative fixed by bolt 15, and the inner space after described shell and the inner shell combination is adjusted according to the change in location of described bolt 15;
Shown in Fig. 7,8, material is that inner shell left side wall 3 exterior bottom of lead glass are installed with a flat board 9, and described dull and stereotyped 9 are provided with a fixed leg 10;
Offer an arch through hole 7 on the wall 3 of a described inner shell left side, described through hole 7 can pass through for tumor-bearing mice tumor locus 8;
Described inner shell left side wall 3 is articulated and connected with inner shell antetheca 5, and sealed by hasp 6 and inner shell 2; The right-hand member of described inner shell 2 is uncovered;
As shown in figure 10, the right wall 11 of described shell 1 is provided with plural air-vent 12.
The length of described shell 1 is 6.3cm, and the length of the box body section of described inner shell 2 is 5.5cm, and the wide and high of described shell 1 is 4cm, and the wide and high of described inner shell 2 is 3.7cm, and described dull and stereotyped 9 are the rectangular plastic plate of long 3cm, wide 3.7cm.
Described inner shell 2 upper ends are opened wide, and utilize the upper wall of shell to be lid; The material of described inner shell 2 is a common plastics.Sponge 16 is laid in the bottom of described inner shell, and tumor-bearing mice can not arbitrarily be moved in inner shell.
The edge of described arch through hole 7 is provided with rubber blanket 17, avoids the poor skin of He Liuchu to be scratched because of tractive and friction in the irradiation experiment.
Experiment set-up procedure: at first open the left wall of inner shell, the tumor locus of tumor-bearing mice is pulled out by described through hole, close inner shell left side wall, and utilize hasp and inner shell sealed; The shank that then tumor-bearing mice is stretched out inner shell is fixed on the fixed leg on the flat board; The inner shell that tumor-bearing mice will be housed then pushes shell, and determine that according to the build of tumor-bearing mice inner shell pushes the degree of depth of shell, inserting bolt and screwing in snib groove and screwed hole is completely fixed shell and inner shell at last, begins to carry out the local irradiation experiment of tumor-bearing mice.

Claims (4)

1. a tumor-bearing mice local irradiation device comprises a shell (1), and described shell (1) is the open lead glass box body of left end; It is characterized in that described tumor-bearing mice local irradiation device also comprises an inner shell (2), described inner shell (2) can insert from the left end of shell (1), and can freely twitch in shell (1); And be provided with positioner between described shell (1) and the inner shell (2);
Left wall (3) exterior bottom of described inner shell (2) is installed with a flat board (9), and described flat board (9) is provided with a fixed leg (10);
Offer a through hole (7) on the described inner shell left side wall (3), described through hole (7) can pass through for tumor-bearing mice tumor locus (8);
Described inner shell left side wall (3) is articulated and connected with inner shell (2), and sealed by hasp (6) and inner shell (2);
The right-hand member of described inner shell (2) is uncovered, and the right wall (11) of described shell (1) is provided with plural air-vent (12).
2. drawer type tumor-bearing mice local irradiation device according to claim 1, it is characterized in that: described positioner comprises a bolt (15) and a snib groove (13), snib groove (13) is located on the antetheca (4) of shell (1), and bolt (15) passes snib groove (13) and links to each other with inner shell.
3. drawer type tumor-bearing mice local irradiation device according to claim 1, it is characterized in that: described inner shell (2) top is uncovered.
4. drawer type tumor-bearing mice local irradiation device according to claim 1 is characterized in that: circular, the square or arch of being shaped as of described through hole (7), the edge of described through hole (7) is provided with rubber blanket (17).
CN2011200920208U 2011-03-31 2011-03-31 Drawer-type local irradiation device for tumor bearing mouse Expired - Fee Related CN202020800U (en)

Priority Applications (1)

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CN2011200920208U CN202020800U (en) 2011-03-31 2011-03-31 Drawer-type local irradiation device for tumor bearing mouse

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Application Number Priority Date Filing Date Title
CN2011200920208U CN202020800U (en) 2011-03-31 2011-03-31 Drawer-type local irradiation device for tumor bearing mouse

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CN202020800U true CN202020800U (en) 2011-11-02

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103081816A (en) * 2011-11-07 2013-05-08 中国辐射防护研究院 Point source irradiating method and tool for chronic irradiation of animals in batch experiments
CN103768723A (en) * 2012-10-22 2014-05-07 上海交通大学医学院附属第九人民医院 Mouse lower-limb radioactivity osteoradionecrosis model construction device
CN113663227A (en) * 2021-09-07 2021-11-19 华东医院 All-wrapping mouse hind limb ultraviolet radiation fixator

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103081816A (en) * 2011-11-07 2013-05-08 中国辐射防护研究院 Point source irradiating method and tool for chronic irradiation of animals in batch experiments
CN103768723A (en) * 2012-10-22 2014-05-07 上海交通大学医学院附属第九人民医院 Mouse lower-limb radioactivity osteoradionecrosis model construction device
CN103768723B (en) * 2012-10-22 2016-03-30 上海交通大学医学院附属第九人民医院 Rat lower limb osteoradionecrosis model construction device
CN113663227A (en) * 2021-09-07 2021-11-19 华东医院 All-wrapping mouse hind limb ultraviolet radiation fixator
CN113663227B (en) * 2021-09-07 2024-05-31 华东医院 Full-wrapping mouse hind limb ultraviolet radiation fixer

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C14 Grant of patent or utility model
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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20111102

Termination date: 20190331

CF01 Termination of patent right due to non-payment of annual fee