CN202015429U - Device for local irradiation on tumor-bearing mouse - Google Patents

Device for local irradiation on tumor-bearing mouse Download PDF

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Publication number
CN202015429U
CN202015429U CN2011200553317U CN201120055331U CN202015429U CN 202015429 U CN202015429 U CN 202015429U CN 2011200553317 U CN2011200553317 U CN 2011200553317U CN 201120055331 U CN201120055331 U CN 201120055331U CN 202015429 U CN202015429 U CN 202015429U
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CN
China
Prior art keywords
tumor
lead glass
glass box
bearing mice
bearing mouse
Prior art date
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Expired - Fee Related
Application number
CN2011200553317U
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Chinese (zh)
Inventor
徐加英
樊赛军
秦立强
焦旸
杨江涛
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Suzhou University
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Suzhou University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou University filed Critical Suzhou University
Priority to CN2011200553317U priority Critical patent/CN202015429U/en
Application granted granted Critical
Publication of CN202015429U publication Critical patent/CN202015429U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The utility model discloses a device for local irradiation on a tumor-bearing mouse. The device comprises a lead glass box that is quite capable of accommodating the tumor-bearing mouse, wherein more than two breather holes are formed on the rear wall of the lead glass box; a through hole for allowing a tumor part of the tumor-bearing mouse to pass through is formed on the front wall of the lead grass box; a board is arranged at the front end of the lead glass box and below the through hole; the board is fixedly connected with the front wall of the lead glass box; and a fixed leg is arranged on the board. The box body of the device is made of lead glass, can achieve an excellent shielding effect and protect other parts of the tumor-bearing mouse from the influences of x-rays under the situation of local irradiation on the tumor-bearing mouse. Due to a sponge at the bottom of the lead glass box, the tumor-bearing mouse in the lead glass box can not act freely, and during an experiment, the part of the tumor-bearing mouse, which is exposed outside an irradiation device, is fixed on the fixed leg, so as to ensure that the tumor-bearing mouse is fixed reliably, and improve the efficiency and quality of the irradiation experiment.

Description

A kind of device that is used for the tumor-bearing mice local irradiation
Technical field
This utility model relates to a kind of radiotherapy device, is specifically related to a kind of device that is used for the tumor-bearing mice local irradiation.
Background technology
Malignant tumor is one of important diseases of current harm humans health, is human first killer of new century, and human survival is constituted the most serious threat.Comparatively sophisticated at present Therapeutic Method has operative treatment, radiotherapy, Drug therapy and immunization therapy four classes.In recent years, tumor radiotherapy had been made significant headway, but unsatisfactory to harm humans life and health therapeutic effect the most serious, that account for the solid tumor of malignant tumor more than 90%; And most radiotherapies produce detrimental effect inevitably to normal structure, organ in inhibition or killing tumor cell, bring misery to the patient, even cause death.In concrete process of experimental, normally utilize mice to carry out irradiation experiment, be about to mice and put into wide mouthed bottle or other glass containers, reuse x ray or other rays shine research.
Sometimes need carry out irradiation research to the part of tumor-bearing mice because of experiment, existing method is to twine the radiation protection material band on one's body mice, only will need the position of irradiation to expose.But radiation protection material is often heavier or harder, very trouble operates, do not reach ideal occlusion effect even can come off, mice is wound and agitation may occurs behind the protective material and cause and can't fix in addition, because absorbed dose of mice and distance square is inverse ratio during irradiation, so mice plays very large effect here apart from the distance of radioactive source,, can have a strong impact on experimental result if mice can not relative fixed.
Summary of the invention
Goal of the invention of the present utility model provides a kind of device that is used for the tumor-bearing mice local irradiation; improvement by structure; can be under to the situation of tumor-bearing mice local irradiation other positions of protection mice be not subjected to the influence of X ray, and mice is fixed in the radiotherapy process.
To achieve the above object of the invention, the technical solution adopted in the utility model is: a kind of device that is used for the tumor-bearing mice local irradiation, described device comprises a box body, wherein, described box body is for holding the lead glass box of tumor-bearing mice fully, the rear wall of described lead glass box is provided with two above air-vents, offers a through hole on the antetheca of described lead glass box, and described through hole can pass through for the tumor-bearing mice tumor locus; The antetheca exterior bottom of described lead glass box is installed with a flat board, and described flat board is provided with a fixed leg.
In the technique scheme, an end and the described rear wall of the upper wall of described lead glass box are hinged, and the other end of described upper wall is connected by the snap close of being located on the described antetheca with described antetheca.
Further technical scheme, sponge is laid in the bottom of described lead glass box.
In the technique scheme, the rear wall of described lead glass box is provided with tag bits.
In the technique scheme, the edge of described through hole is provided with rubber blanket.
Experiment set-up procedure: the upper wall of opening the lead glass box, tumor-bearing mice put into the lead glass box and with the upper wall of lead glass box and antetheca locking, tumor locus with tumor-bearing mice stretches out outside the lead glass box via the through hole on the antetheca then, and be that the shank of tumor-bearing mice is fixed on the described fixed leg with exposure portion, begin to carry out the local irradiation experiment of tumor-bearing mice.
Further technical scheme, described plate is simple glass plate or plastic plate, described fixed leg is a common plastics.
In the technique scheme, the length of described lead glass box is 8~10cm, the length of its antetheca and wide be 3~4cm, the diameter of described through hole is 1.0~1.5cm.
Because the technique scheme utilization, this utility model compared with prior art has following advantage:
1. box body of the present utility model is made by lead glass, can play good shield effectiveness, and other positions of protection mice are not subjected to the influence of X ray under to the situation of tumor-bearing mice local irradiation.
2. the sponge of this utility model at the bottom of the lead glass box makes the mice can't be free movable in box, and the position that during experiment tumor-bearing mice is exposed to outside the irradiation devices is fixed on the fixed leg, guarantee the fixing reliable of mice, improved the efficient and the quality of irradiation experiment.
3. this utility model is provided with air-vent, can guarantee the eupnea of tumor-bearing mice in experimentation; Be provided with tag bits simultaneously, can recording-related information, avoid operate miss.
4. this utility model is lined with rubber blanket at the edge of through hole, stops the poor skin of He Liuchu to be scratched because of tractive and friction in the irradiation experiment.
5. this utility model comprises lead glass box, plate and is fixed in fixed leg on the plate, and simple in structure, easy processing is suitable for extensive utilization.
Description of drawings
Fig. 1 is the schematic perspective view of this utility model embodiment one;
Fig. 2 is the right view of embodiment one;
Fig. 3 is the profile along Fig. 1 center line A-A;
Wherein: 1, lead glass box; 2, rear wall; 3, air-vent; 4, antetheca; 5, through hole; 6, plate; 7, fixed leg; 8, upper wall; 9, snap close; 10, sponge; 11, tag bits; 12, rubber blanket; 13, tumor locus.
The specific embodiment
Below in conjunction with drawings and Examples this utility model is further described:
Embodiment one: referring to Fig. 1, shown in Figure 2, a kind of device that is used for the tumor-bearing mice local irradiation, described device comprises that one can hold the lead glass box 1 of tumor-bearing mice fully, and according to the build of tumor-bearing mice, the length of described lead glass box 1 is the length and the wide 3~4cm of being of 8~10cm, antetheca; The rear wall 2 of described lead glass box is provided with two above air-vents 3, offers a through hole 5 that can pass through for the tumor locus 13 of tumor-bearing mice on the antetheca 4 of described lead glass box, and the diameter of described through hole 5 is 1.0~1.5cm; One end and the described rear wall 2 of the upper wall 8 of described lead glass box are hinged, and the other end of described upper wall 8 is connected by the snap close of being located on the described antetheca 9 with described antetheca 4; The front end of described lead glass box, the below of described through hole are provided with a simple glass plate 6, and described glass plate 6 is fixedlyed connected with the antetheca 4 of lead glass box, and described glass plate 6 is provided with a fixed leg 7.Sponge 10 is laid in the bottom of described lead glass box, stops tumor-bearing mice free movable in the lead glass box.The rear wall 2 of described lead glass box is provided with tag bits 11, can help experimenter's recording-related information, avoids maloperation.The edge of described through hole 5 is provided with rubber blanket 12, stops the poor skin of He Liuchu to be scratched because of tractive and friction in the irradiation experiment.
Experiment set-up procedure: the upper wall of opening the lead glass box, tumor-bearing mice put into the lead glass box and with the upper wall of lead glass box and antetheca locking, tumor locus with tumor-bearing mice stretches out outside the lead glass box via the through hole on the antetheca then, and be that the shank of tumor-bearing mice is fixed on the described fixed leg with exposure portion, begin to carry out the local irradiation experiment of tumor-bearing mice.
Embodiment two: the structure of embodiment two and embodiment one are basic identical, and difference is: described plate 6 is plastic plate.

Claims (5)

1. device that is used for the tumor-bearing mice local irradiation, described device comprises a box body, it is characterized in that: described box body is for holding the lead glass box (1) of tumor-bearing mice fully, one end of described lead glass box upper wall (8) and rear wall (2) are hinged, the other end of described upper wall (8) is connected by the snap close of being located on the described antetheca (9) with antetheca (4), the rear wall (2) of described lead glass box (1) is provided with two above air-vents (3), offer a through hole (5) on the antetheca of described lead glass box (4), described through hole (5) can pass through for tumor-bearing mice tumor locus (13); Antetheca (4) exterior bottom of described lead glass box (1) is installed with a flat board (6), and described flat board (6) is provided with a fixed leg (7).
2. the device that is used for the tumor-bearing mice local irradiation according to claim 1 is characterized in that: sponge (10) is laid in the bottom of described lead glass box (1).
3. the device that is used for the tumor-bearing mice local irradiation according to claim 1 is characterized in that: the rear wall of described lead glass box (2) is provided with tag bits (11).
4. the device that is used for the tumor-bearing mice local irradiation according to claim 1 is characterized in that: the edge of described through hole (5) is provided with rubber blanket (12).
5. the device that is used for the tumor-bearing mice local irradiation according to claim 1 is characterized in that: the length of described lead glass box is 8~10cm, the length of its antetheca and wide be 3~4cm, the diameter of described through hole is 1.0~1.5cm.
CN2011200553317U 2011-03-04 2011-03-04 Device for local irradiation on tumor-bearing mouse Expired - Fee Related CN202015429U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2011200553317U CN202015429U (en) 2011-03-04 2011-03-04 Device for local irradiation on tumor-bearing mouse

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2011200553317U CN202015429U (en) 2011-03-04 2011-03-04 Device for local irradiation on tumor-bearing mouse

Publications (1)

Publication Number Publication Date
CN202015429U true CN202015429U (en) 2011-10-26

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Application Number Title Priority Date Filing Date
CN2011200553317U Expired - Fee Related CN202015429U (en) 2011-03-04 2011-03-04 Device for local irradiation on tumor-bearing mouse

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103565537A (en) * 2012-07-23 2014-02-12 中国辐射防护研究院 Mouse irradiation disc fixing device
CN105148411A (en) * 2015-09-08 2015-12-16 黄勇 Experimental device for verifying the treatment effect of near-infrared light on Alzheimer's disease and application of the device
CN108498951A (en) * 2018-02-06 2018-09-07 王文春 Magnetic field shielding case

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103565537A (en) * 2012-07-23 2014-02-12 中国辐射防护研究院 Mouse irradiation disc fixing device
CN105148411A (en) * 2015-09-08 2015-12-16 黄勇 Experimental device for verifying the treatment effect of near-infrared light on Alzheimer's disease and application of the device
CN105148411B (en) * 2015-09-08 2018-03-06 黄勇 Verify experimental provision and application of the near infrared light to AD therapy effect
CN108498951A (en) * 2018-02-06 2018-09-07 王文春 Magnetic field shielding case

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20111026

Termination date: 20190304