CN215778852U - Fixing device for irradiation mouse experiment - Google Patents
Fixing device for irradiation mouse experiment Download PDFInfo
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- CN215778852U CN215778852U CN202120427976.2U CN202120427976U CN215778852U CN 215778852 U CN215778852 U CN 215778852U CN 202120427976 U CN202120427976 U CN 202120427976U CN 215778852 U CN215778852 U CN 215778852U
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Abstract
The utility model provides a fixing device for an irradiation mouse experiment, which comprises a box body, wherein a plurality of vertical partition plates are sequentially arranged in the box body at intervals to divide the box body into a plurality of transversely arranged separation bins for placing a plurality of mice, an opening at the top end of the box body is sealed in a sliding manner through a cover plate, a through groove is formed in the front end of each separation bin, a short slide rail is embedded in the bottom end of each separation bin, the bottom ends of the slide rails are connected to the short slide rails in a sliding manner, an elastic part is connected between one end of each short slide rail and the bottom end of each slide rail, a push plate is transversely arranged in the bottom end of the box body and fixedly connected with one end of each short slide rail, the push plates are driven to move by rotating a screw rod to synchronously drive the short slide rails to longitudinally move along the inner part of the bottom end of each separation bin so as to drive each slide rail to longitudinally integrally move, so as to conveniently and efficiently adjust and fix the mice, and each mouse is collided to drive the elastic part to stretch or shrink so that the slide plates are firmly collided and fixed with the mice, so as to realize the function of automatic adaptability adjustment for each mouse.
Description
Technical Field
The utility model relates to the technical field of fixing devices used in living animal irradiation experiments, in particular to a fixing device for an irradiation mouse experiment.
Background
At present, malignant tumors are one of important diseases which endanger human health, and pose serious threats to human survival, and the currently mature treatment methods include four types, namely surgical treatment, radiotherapy, drug treatment and immunotherapy. In recent years, tumor radiotherapy has made great progress, but most radiotherapy inevitably produces damage to normal tissues and organs while inhibiting or killing tumor cells, bringing pain and harm to patients, aiming at the problem, in the specific experimental research process, a mouse is generally used for irradiation experiment, namely, the mouse is put into a container, then x-rays or other rays are used for irradiation research, and in order to ensure the accurate reliability of the experiment, a lot of mice are required to be irradiated simultaneously for experiment, and the experiment is carried out by comparing the way that the mouse irradiates a specific position.
However, the existing experimental container is often simple in structure and single in specification, and especially for a plurality of mice in batch experiments, the mice cannot be completely fixed and can freely move easily, so that it is obviously difficult to stably and accurately irradiate specific parts of the mice, which causes inconvenience in use and seriously affects experimental results, and thus, the existing experimental container is not enough to meet higher practical requirements.
SUMMERY OF THE UTILITY MODEL
In view of the above, the present invention provides a fixing device for an irradiation mouse experiment, so as to achieve the functions of conveniently, synchronously and efficiently adjusting the stable fixing positions of a plurality of mice, and automatically adjusting the fixing positions of the plurality of mice according to the adaptation of the mice.
In view of the above, the present invention provides a fixing device for an irradiation rat experiment, comprising:
the box body is designed to be of a top end opening structure, and a plurality of vertical partition plates are sequentially arranged in the box body at intervals so as to divide the box body into a plurality of transversely arranged partition bins;
the cover plate is used for sliding and inserting the top end opening of the closed box body;
the through groove is formed in the front end of the partition bin;
the short slide rail is embedded in the bottom end of the separation bin;
the sliding plate is vertically arranged in the separation bin, and the bottom end of the sliding plate is connected to the short sliding rail in a sliding manner so as to freely slide along the longitudinal direction;
the elastic piece is connected between one end of the short slide rail and the bottom end of the slide plate;
the push plate is transversely arranged in the bottom end of the box body and is fixedly connected with one end of the short slide rail;
the screw rod, screw rod one end swing joint is in the box body bottom to can free axial rotation, the other end runs through out outside the box body, and the push pedal is worn to locate perpendicularly to the screw rod to with push pedal thread toothing, through rotating the screw rod, with the removal of transmissible push pedal, with the inside longitudinal movement of short slide rail edge partition storehouse bottom.
Preferably, the vertical partition plate is provided with a clamping groove, and the cover plate can be transversely inserted into the top end of the closed box body along the clamping groove in a sliding manner.
Preferably, the clamping grooves are sequentially arranged on the vertical partition plates at intervals in parallel along different heights.
Preferably, a plurality of side grooves are arranged on the inner side wall of the box body at intervals in parallel, and each side groove is equal to each clamping groove in height in sequence.
Preferably, a plurality of partition plate grooves are sequentially arranged on the inner wall of the box body at intervals, and the vertical partition plates can be attached to and slidably inserted into the box body along the partition plate grooves.
Preferably, the through groove comprises a vertical groove extending vertically and a circular groove communicated with the bottom end of the vertical groove.
Preferably, the side end of the sliding plate is attached to the inner side wall of the separation bin.
Preferably, the elastic member is a spring.
Preferably, the screw rod penetrates out of the box body, and one end of the screw rod is in threaded connection with a locking nut.
Preferably, the box body and the vertical clapboard are both provided with air holes.
From the above, the fixing device for the irradiation mouse experiment provided by the utility model has the advantages that the box body is arranged, the box body is internally provided with the vertical partition plates at intervals in sequence to divide the box body into the plurality of transversely arranged partition bins for separating and placing a plurality of mice for the experiment in sequence, the cover plate is arranged to be inserted in the top end opening of the box body in a sliding way so as to play a role of stably and fixedly sealing and fixing the mice in the vertical direction, the front end of each partition bin is provided with the through groove for the tail of the mouse to penetrate out of the through groove so as to be beneficial to further stably and fixedly, the short slide rail is embedded in the bottom end of each partition bin, the sliding plate is vertically arranged in each partition bin, the bottom end of each sliding plate is slidably connected to the short slide rail so as to freely slide along the longitudinal direction, the elastic part is connected between one end of the short slide rail and the bottom end of the sliding plate, the push plate is transversely arranged in the bottom end of the box body and fixedly connected with one end of the short slide rail, simultaneously screw rod one end swing joint is in the box body bottom, but in order free axial rotation, the other end runs through out outside the box body, and the screw rod is worn to locate the push pedal perpendicularly, and with push pedal thread engagement, thereby when using the regulation, only through rotating the screw rod, move with the transmission push pedal, with the inside longitudinal movement of synchronous drive short slide rail edge partition storehouse bottom, thereby drive each slide along vertical bulk movement, in order to realize along the vertical direction on whole synchronous regulation, in order to do benefit to the fixed mouse of convenient synchronous high-efficient adjustment, and because the mouse size of same batch experiment also can be slightly different, thereby be corresponding to the size of each mouse, drive the elastic component with the conflict and stretch or shrink, in order to make the fixed mouse of slide firm conflict, in order to realize still can automatic adaptability adjustment's function to each mouse.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic structural diagram of an embodiment of the present invention;
FIG. 2 is an enlarged schematic view of FIG. 1 at A according to an embodiment of the present invention;
fig. 3 is a schematic top view of the short slide rail and the slide plate according to the embodiment of the utility model.
In the figure: 1. a box body; 2. a vertical partition plate; 21. a card slot; 3. separating the bins; 31. a through groove; 4. a cover plate; 5. a short slide rail; 6. a slide plate; 7. an elastic member; 8. pushing the plate; 9. a screw; 91. locking the nut; 10. and a side groove.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to specific embodiments and the accompanying drawings.
It is to be noted that technical terms or scientific terms used in the embodiments of the present invention should have the ordinary meanings as understood by those having ordinary skill in the art to which the present disclosure belongs, unless otherwise defined. The use of "first," "second," and similar terms in this disclosure is not intended to indicate any order, quantity, or importance, but rather is used to distinguish one element from another. The word "comprising" or "comprises", and the like, means that the element or item listed before the word covers the element or item listed after the word and its equivalents, but does not exclude other elements or items. The terms "connected" or "coupled" and the like are not restricted to physical or mechanical connections, but may include electrical connections, whether direct or indirect. "upper", "lower", "left", "right", and the like are used merely to indicate relative positional relationships, and when the absolute position of the object being described is changed, the relative positional relationships may also be changed accordingly.
A fixing device for an irradiation mouse experiment is disclosed, as shown in figures 1 to 3, comprising a box body 1, wherein the box body 1 is designed to be of a top end opening structure, a plurality of vertical partition boards 2 are arranged in the box body 1 at intervals in sequence to divide the interior of the box body 1 into a plurality of transversely arranged partition bins 3, a cover plate 4 is arranged to be inserted into and close the top end opening of the box body 1 in a sliding manner, a through groove 31 is arranged at the front end of each partition bin 3, a short slide rail 5 is embedded in the bottom end of each partition bin 3, a slide plate 6 is vertically arranged in each partition bin 3, the bottom end of each slide plate 6 is slidably connected to the corresponding short slide rail 5 so as to be freely slidable along the longitudinal direction, an elastic part 7 is connected between one end of each short slide rail 5 and the bottom end of each slide plate 6, a push plate 8 is transversely arranged in the bottom end of the box body 1, one end of each push plate 8 is fixedly connected with one end of each short slide rail 5, a screw rod 9 is arranged, one end of each screw rod is movably connected to the bottom end of the box body 1 so as to be capable of freely axially rotating, the other end penetrates out of the box body 1, the screw rod 9 vertically penetrates through the push plate 8 and is in threaded engagement with the push plate 8, and the screw rod 9 is rotated to drive the push plate 8 to move so as to drive the short slide rail 5 to longitudinally move along the inner part of the bottom end of the separation bin 3.
The utility model divides the box body 1 into a plurality of transversely arranged separation chambers 3 for separating and placing a plurality of mice for experiments in sequence by arranging the box body 1, a plurality of vertical partition plates 2 are sequentially arranged in the box body 1 at intervals, a cover plate 4 is arranged for sliding and inserting the top end opening of the box body 1 so as to play a role of stably and fixedly sealing the mice in the vertical direction, the front end of the separation chamber 3 is provided with a through groove 31 for the tail of the mouse to penetrate out of the through groove 31 so as to be beneficial to further stable and fixed, meanwhile, a short slide rail 5 is embedded in the bottom end of the separation chamber 3, a slide plate 6 is vertically arranged in the separation chamber 3, the bottom end of the slide plate 6 is slidably connected with the short slide rail 5 so as to freely slide along the longitudinal direction, an elastic piece 7 is connected between one end of the short slide rail 5 and the bottom end of the slide plate 6, a push plate 8 is horizontally arranged in the bottom end of the box body 1, and one end of the short slide rail 5 are fixedly connected, meanwhile, one end of a screw rod 9 is movably connected in the bottom end of the box body 1 to be capable of freely rotating axially, the other end penetrates out of the box body 1, the screw rod 9 vertically penetrates through the push plate 8 and is meshed with the push plate 8 in a threaded manner, when the mouse is used and adjusted, the screw rod 9 is only rotated to drive the push plate 8 to move so as to synchronously drive the short slide rails 5 to longitudinally move along the inner part of the bottom end of the separation bin 3, so that each slide plate 6 is driven to longitudinally integrally move, the integral synchronous adjustment along the longitudinal direction is realized, the mouse can be conveniently, synchronously and efficiently adjusted and fixed, and because mouse body types in the same batch of experiments are slightly different, the elastic parts 7 are driven to stretch or shrink by being collided corresponding to mouse body types, so that the slide plates 6 are stably collided and fixed with the mouse, the function of automatic adaptive adjustment of each mouse can be realized, and meanwhile, a movable lead plate can be arranged above the fixing device during the experiments, the lead plate thickness is about 5mm for carry out local sheltering from to the radiation, and the lead plate that is used for sheltering from can be provided with two, so that nimble combination adjustment, in order to realize carrying out specific local accurate experiment of shining to the mouse after firm fixing.
In the embodiment of the utility model, the vertical partition plate 2 is provided with a clamping groove 21, and the cover plate 4 can be transversely inserted into the top end of the closed box body 1 along the clamping groove 21 in a sliding manner, so that the stable sliding insertion and blocking are facilitated.
In the embodiment of the utility model, a plurality of clamping grooves 21 are sequentially arranged in parallel at intervals along different heights on the vertical partition plate 2, so that the clamping grooves 21 along different heights can be slidably inserted into the cover plate 4 to be sealed according to different body sizes of mice, and the clamping grooves can be conveniently adjusted in the vertical direction to be adaptive to stably fix the mice.
In the embodiment of the present invention, a plurality of side grooves 10 are spaced in parallel on the inner side wall of the box body 1, and each side groove 10 is equal in height to each slot 21 in turn, so that the cover plate 4 inserted slidably along the slot 21 can be inserted into the side groove 10 correspondingly, which is beneficial to further stable use.
In the embodiment of the utility model, a plurality of partition plate grooves are sequentially arranged on the inner wall of the box body 1 at intervals, and the vertical partition plates 2 can be attached along the partition plate grooves and slidably inserted into the box body 1, so that the convenient and fast detachable assembly and use are realized.
In the embodiment of the present invention, the through groove 31 includes a vertical groove extending vertically and a circular groove communicating with the bottom end of the vertical groove, so that the tail of the mouse is inserted into the circular groove along the vertical groove penetrating from the top end, which is beneficial to conveniently placing and fixing the mouse.
In the embodiment of the utility model, the side end of the sliding plate 6 is attached to the inner side wall of the separation chamber 3, so as to be beneficial to further stable attaching movement.
In the embodiment of the present invention, the elastic member 7 is a spring.
In the embodiment of the utility model, the end of the screw 9, which penetrates out of the box body 1, is in threaded connection with the locking nut 91, so that the locking nut 91 can be rotated to abut against the outer wall of the box body 1, thereby realizing efficient locking.
In the embodiment of the utility model, the box body 1 and the vertical clapboard 2 are both provided with air holes.
In the fixing device for the irradiation mouse experiment disclosed by the utility model, when in use, a plurality of vertical partition plates 2 are sequentially arranged in a box body 1 at intervals to divide the interior of the box body 1 into a plurality of transversely arranged separation bins 3 for placing a plurality of mice, an opening at the top end of the box body 1 is slidably inserted and sealed through a cover plate 4 so as to stably seal and fix the mice in the vertical direction, a through groove 31 is formed at the front end of the separation bin 3 so that tails of the mice can penetrate out of the through groove 31, a short slide rail 5 is embedded in the bottom end of the separation bin 3, the bottom end of a slide plate 6 is slidably connected onto the short slide rail 5, an elastic part 7 is connected between one end of the short slide rail 5 and the bottom end of the slide plate 6, a push plate 8 is transversely arranged in the bottom end of the box body 1, the push plate 8 is fixedly connected with one end of the short slide rail 5, the push plate 8 is driven to move by rotating a screw rod 9 so as to synchronously drive the short slide rail 5 to longitudinally move along the interior of the bottom end of the separation bin 3, so as to drive each sliding plate 6 to move along the longitudinal direction integrally, so as to adjust and fix the mouse conveniently and efficiently, and each mouse is collided to drive the elastic part 7 to stretch or contract, so that the sliding plates 6 are firmly collided and fixed with the mouse, so as to realize the function of automatic adaptability adjustment for each mouse, during the experiment at the same time, a movable lead plate can be arranged above the fixing device, the thickness of the lead plate is about 5mm and is used for shielding the radiation locally, so as to realize the local accurate irradiation experiment of the mouse after being firmly fixed, wherein, the vertical clapboard 2 is provided with a plurality of clamping grooves 21, the clamping grooves 21 are arranged in parallel at intervals along different heights on the vertical clapboard 2, the inner side wall of one side of the box body 1 is provided with a plurality of side grooves 10 in parallel at intervals, the cover plate 4 is inserted in a sliding way along the clamping grooves 21 and can be correspondingly inserted into the side grooves 10, the inner wall of the box body 1 is provided with a plurality of clapboard grooves in sequence at intervals, erect baffle 2 in order can follow the laminating of baffle groove and slide and insert box body 1, lead to groove 31 including vertical extension perpendicular groove and communicate in the circular slot of erecting the tank bottom, 6 side of slide are laminated in 3 inside walls in compartment, and elastic component 7 is the spring, and threaded connection has lock nut 91 outside box body 1 is worn out to screw rod 9, and box body 1 has all seted up the bleeder vent on the baffle 2 with erecting.
Those of ordinary skill in the art will understand that: the discussion of any embodiment above is meant to be exemplary only, and is not intended to intimate that the scope of the disclosure, including the claims, is limited to these examples; within the idea of the utility model, also features in the above embodiments or in different embodiments may be combined, steps may be implemented in any order, and there are many other variations of the different aspects of the utility model as described above, which are not provided in detail for the sake of brevity.
The embodiments of the utility model are intended to embrace all such alternatives, modifications and variances that fall within the broad scope of the appended claims. Therefore, any omissions, modifications, substitutions, improvements and the like that may be made without departing from the spirit and principles of the utility model are intended to be included within the scope of the utility model.
Claims (10)
1. A fixing device for an irradiation mouse experiment is characterized by comprising:
the box body is designed to be of a top end opening structure, and a plurality of vertical partition plates are sequentially arranged in the box body at intervals so as to divide the box body into a plurality of transversely arranged partition bins;
the cover plate is used for sealing the top end opening of the box body in a sliding and inserting manner;
the through groove is formed in the front end of the separation bin;
the short slide rail is embedded in the bottom end of the separation bin;
the sliding plate is vertically arranged in the separation bin, and the bottom end of the sliding plate is connected to the short sliding rail in a sliding mode so as to freely slide along the longitudinal direction;
the elastic piece is connected between one end of the short slide rail and the bottom end of the slide plate;
the push plate is transversely arranged inside the bottom end of the box body and is fixedly connected with one end of the short slide rail;
and one end of the screw rod is movably connected into the bottom end of the box body so as to be capable of freely rotating axially, the other end of the screw rod penetrates out of the box body, the screw rod vertically penetrates through the push plate and is in threaded engagement with the push plate, and the screw rod is rotated so as to be capable of driving the push plate to move so as to drive the short slide rail to longitudinally move along the inner part of the bottom end of the separation bin.
2. The fixing device of claim 1, wherein the vertical partition is provided with a slot, and the cover plate is slidably inserted along the slot to close the top end of the box body.
3. The fixing device for the irradiation mouse experiment as claimed in claim 2, wherein a plurality of the slots are sequentially arranged on the vertical partition board at intervals in parallel along different heights.
4. The fixing device for the irradiation mouse experiment as claimed in claim 3, wherein a plurality of side grooves are arranged on the inner side wall of the box body at intervals in parallel, and each side groove is sequentially as high as each clamping groove.
5. The fixing device for the irradiation mouse experiment as claimed in claim 1, wherein a plurality of partition plate slots are sequentially arranged on the inner wall of the box body at intervals, and the vertical partition plates can be attached to and slidably inserted into the box body along the partition plate slots.
6. The fixing device of claim 1, wherein the through slot comprises a vertical slot extending vertically and a circular slot connected to a bottom end of the vertical slot.
7. The apparatus of claim 1, wherein the side end of the sliding plate is engaged with the inner side wall of the compartment.
8. The fixing device of claim 1, wherein the elastic member is a spring.
9. The fixing device for the irradiation mouse experiment as claimed in claim 1, wherein a locking nut is connected to one end of the screw rod, which penetrates out of the box body, in a threaded manner.
10. The fixing device of claim 1, wherein the box body and the vertical partition are provided with air holes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120427976.2U CN215778852U (en) | 2021-02-26 | 2021-02-26 | Fixing device for irradiation mouse experiment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202120427976.2U CN215778852U (en) | 2021-02-26 | 2021-02-26 | Fixing device for irradiation mouse experiment |
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| Publication Number | Publication Date |
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| CN215778852U true CN215778852U (en) | 2022-02-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202120427976.2U Active CN215778852U (en) | 2021-02-26 | 2021-02-26 | Fixing device for irradiation mouse experiment |
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| CN (1) | CN215778852U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115607860A (en) * | 2022-12-15 | 2023-01-17 | 首都医科大学宣武医院 | Device and method for establishing carotid artery stenosis mouse model after radiotherapy |
-
2021
- 2021-02-26 CN CN202120427976.2U patent/CN215778852U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115607860A (en) * | 2022-12-15 | 2023-01-17 | 首都医科大学宣武医院 | Device and method for establishing carotid artery stenosis mouse model after radiotherapy |
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