CN201492711U - Cordyceps sinensis tablet - Google Patents

Cordyceps sinensis tablet Download PDF

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Publication number
CN201492711U
CN201492711U CN2009203038170U CN200920303817U CN201492711U CN 201492711 U CN201492711 U CN 201492711U CN 2009203038170 U CN2009203038170 U CN 2009203038170U CN 200920303817 U CN200920303817 U CN 200920303817U CN 201492711 U CN201492711 U CN 201492711U
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China
Prior art keywords
tablet
radix
cordyceps
fructus
cordyceps sinensis
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Expired - Lifetime
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CN2009203038170U
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Chinese (zh)
Inventor
张雪峰
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QINGHAI CHUNTIAN MEDICAL RESOURCE TECHNOLOGY UTILIZATION CO., LTD.
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张雪峰
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Priority to CN2009203038170U priority Critical patent/CN201492711U/en
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Publication of CN201492711U publication Critical patent/CN201492711U/en
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Abstract

The utility model belongs to the field of pharmacy, and particularly relates to a cordyceps sinensis tablet which is a tablet formed by pressing cordyceps sinensis used as main raw materials. The utility model aims to provide a cordyceps sinensis tablet without laminates, whose pharmaceutical ingredients between tablet layers are homogeneous; the tablet is formed by at least two tablet layers, wherein at least one tablet layer is prepared after the cordyceps sinensis is crushed, and at least one tablet layer is prepared after tonics are crushed or active ingredients in the tonics are extracted; the tablet layer is layered up and down or layered inside and outside. Through the improvement, when the tablet layers adopt different raw materials to prepare the tablet, through the control of the weight or the thickness parameter of the tablet layers, the ingredients contained in the prepared tablet and the content of the ingredients can be consistent, and the errors are controlled within an allowable range. The technical scheme reduces the mixing step and saves the operation time, and the process is simple and can be realized on original tablet production equipment without increasing the equipment cost, thereby providing a new choice for the preparation of the cordyceps sinensis tablet.

Description

The Cordyceps sheet
Technical field
This utility model belongs to pharmaceutical field, is specifically related to the Cordyceps sheet, and it is to be the tablet that the raw material compacting forms with the Cordyceps.
Background technology
Chinese medicinal tablet is meant that medicinal substances extract, medicinal substances extract add the medical material fine powder or the medical material fine powder is suppressed disk shape or the special-shaped flaky dosage form that forms with suitable auxiliary materials and mixing.When medical material is used with compound compatibility, relate to the processing of multi-flavor raw material during preparation, when becoming fine powder to suppress, pulverizing medicinal materials finds, because medical material exists density variation and addition difference, make that medicinal powder is difficult for mix homogeneously when mixing, some drugs can occur and be distributed in the upper strata more, some drugs is distributed in the situation of lower floor more, thereby implement to cause after tabletting is handled the component and the constituent content heterogeneity of contained drug in every tablet of tablet, influence the drug effect performance, as realizing the purpose of some drugs competence exertion drug effect under specific proportion relation.
When the inventor adopts Cordyceps and other medical materials to be mixed with Chinese medicinal tablet in the past, need long-time mixing just can make Cordyceps and mix homogeneously, if incorporation time is not enough, make the tablet that suppresses that the situation of colored sheet be arranged, influence attractive in appearancely, be unfavorable for selling, can increase time cost if will mix for a long time.
So, be badly in need of seeking a kind of technical scheme that can solve Cordyceps film clips sheet.
The utility model content
The technical problem that this utility model solved provides ingredient homogeneous between a kind of each sheet, does not have the Cordyceps sheet of flower sheet.
This utility model Cordyceps sheet is to be primary raw material with the Cordyceps, is equipped with the tablet that tonic compacting commonly used forms, and is made up of two-layer at least lamella; Wherein, at least one synusia layer gets for Cordyceps pulverizing back preparation, and at least one synusia layer pulverizes the back for tonic or extraction active component preparation wherein gets.
Above lower leaf between the lamella, or with inside and outside layering.By above-mentioned improvement, when each lamella adopted different material to prepare tablet, weight by controlling each lamella or thickness parameter can make contained component and constituent content unanimity in the gained tablet, and error control is in the allowed band value.
During preparation Cordyceps powder, should be crushed to particle diameter is that 1~150 μ m, control powder moisture are 5~18%; Preferable particle size is that 1~50 μ m, control powder moisture are 8~18%.The control above-mentioned parameter can be so that the Cordyceps powder can adopt direct compression technology, or adopts repeatedly or the technology of secondary tabletting, or adopts the technology of dry granule tabletting to carry out tabletting.By adopting technique scheme, do not adding under the situation of any adjuvant, the Cordyceps lamella outward appearance that makes is good, pitted skin rate and sliver rate are low, tablet hardness, disintegration, friability meet the tablet quality requirement, and this hardness can also guarantee that the later stage carries out the processing of coating, overlay film to this tablet, is unlikely to cracked in preparation process.The detailed process method is participated in the Chinese patent application 200810303308.8 that the applicant has applied for, aweto micropowder tablet and preparation method thereof.
If will carry out tabletting again after effective site in the gained tonic or active component mix and to cause mixing the homogeneity that inequality influences each sheet with the Cordyceps of separately pulverizing and tonic or with extracting by existing method through pulverizing, if want mix homogeneously, must increase the operating time, increase energy consumption, be unfavorable for controlling production cost.The inventor is pressed into the tablet of levels structure with the powder of Cordyceps powder and tonic or extraction gained effective site or active component when concrete the application, the tablet of making has two-layer lamella at least; Wherein a kind of component (as the Cordyceps powder) is suppressed the heart in blocks after maybe will pulverizing, again with another kind of component (as the powder of tonic or extract gained effective site or active component) bag pressure outside the sheet heart, form the ectonexine structure that sheet is arranged in the sheet, can also be outside this structure again the powder or the tonic of bag pressure Cordyceps powder or tonic extract gained effective site or active component, the tablet of making has two-layer lamella at least.In the process of preparation tablet, can also be aided with suitable adjuvant according to the character of medical material and carry out preparation.
The raw material tonic that this utility model tablet adopts is according to the tonic under the criteria for classification regulation item of Chinese materia medica, Radix Ginseng is specifically arranged, Radix Panacis Quinquefolii, Radix Codonopsis, Radix Pseudostellariae, Rhizoma Polygonati, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Seem Lablab Album, Fructus Jujubae, Radix Glycyrrhizae, maltose, Cornu Cervi Pantotrichum, Cornu Cervi, Colla cornus cervi, Herba Epimedii, Rhizoma Curculiginis, Radix Morindae Officinalis, Fructus Psoraleae, Semen Juglandis, Herba Cistanches, Fructus Alpiniae Oxyphyllae, Semen Cuscutae, Gecko, Herba Cynomorii, Semen Trigonellae, Fructus Cnidii, Rhizoma Drynariae, Testis et penis callorhini, Radix Dipsaci, the Cortex Eucommiae, Rhizoma Cibotii, Radix Rehmanniae Preparata, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Colla Corii Asini, Fructus Mori, Arillus Longan, Radix Adenophorae (Radix Glehniae), Radix Asparagi, Radix Ophiopogonis, Herba Dendrobii, Rhizoma Polygonati Odorati, Bulbus Lilii, Fructus Lycii, Fructus Ligustri Lucidi, Herba Ecliptae, Carapax et Plastrum Testudinis, Colla Plastri Testudinis, Carapax Trionycis, Colla carapax Trionycis, Herba Taxilli, Ganoderma spore, at least a in the Radix Astragali used the powder of above-mentioned tonic or through extracting the effective site or the active component of gained.Can also adopt the Chinese medicine granules or the Chinese drugs powder of at present commercially available single component to use, use, make the multilayer tablet of levels structure or external and internal compositions, have the advantage that is easy to carry and takes according to the clinical compatibility that needs as the raw material of one of lamella.
Adopt the tablet of technique scheme preparation, overcome because of Cordyceps mixes inequality with tonic and caused component and the big defective of constituent content difference between each sheet of finished tablet, this utility model Cordyceps sheet finds out that because of the color of Cordyceps and tonic is different tangible layering is arranged, also can answer the color of medical material itself when mixing other raw materials and find out that tangible layering is arranged, this utility model tablet and conventional tablet can be distinguished by consumer when buying this series products, have identification and false proof effect.Because of having reduced blend step, saved the operating time at preparation this utility model tablet, technology is easy, can realize on original tablet manufacturing equipment, need not to increase equipment cost, for preparation Cordyceps sheet provides a kind of new selection.
Description of drawings
Fig. 1 is the multilayer tablet of this utility model levels structure.
Fig. 2 is the multilayer tablet of this utility model ectonexine structure.
Fig. 3 is the multilayer tablet of this utility model ectonexine structure.
Be labeled as among the figure: the last lamella of 1-, lamella under the 2-, the 3-sheet heart, 4-first outer plies, 5-second outer plies.
The specific embodiment
Below by to the description of this utility model specific embodiment explanation but do not limit this utility model.
Is that example prepares tablet with Cordyceps (hereinafter to be referred as Cordyceps) as primary raw material.
As shown in Figure 1, respectively Cordyceps is crushed to the powder of 5-20 μ m, after Colla Corii Asini is crushed to fine powder, is pressed into the tablet of levels structure.Or respectively Cordyceps is crushed to the powder of 37-44 μ m, after Radix Panacis Quinquefolii powder is broken to fine powder, be pressed into the tablet of levels structure.Or respectively Cordyceps is crushed to the powder of 120-150 μ m, after Radix Pseudostellariae is crushed to fine powder, be pressed into the tablet of levels structure.
As shown in Figure 2, Cordyceps is crushed to the powder compaction heart 3 in blocks of 37-44 μ m, again the donkey-hide gelatin fine powder bag pressure is formed first outer plies 4 outside the sheet heart 3, form the ectonexine structure that sheet is arranged in the sheet.Or Cordyceps is crushed to the powder compaction heart 3 in blocks of 5-10 μ m, and again the sporoderm-broken Ganoderma spore bag pressure is formed first outer plies 4 outside the sheet heart 3, form the ectonexine structure that sheet is arranged in the sheet.
As shown in Figure 3, Cordyceps is crushed to the powder compaction heart 3 in blocks of 37-44 μ m, again the sporoderm-broken Ganoderma spore bag pressure is formed first outer plies 4 outside the sheet heart 3, the bag pressure donkey-hide gelatin fine powder forms second outer plies 5 outside first outer plies 4 again.In the preparation process, also can be with the donkey-hide gelatin fine powder compressed tablet heart 3, bag pressure Cordyceps powder forms first outer plies 4 outside the sheet heart 3 again, crushes the wall Ganoderma spore in 4 outsourcings of first outer plies again and forms second outer plies 5; Perhaps the component of the changing plate heart 3 and first outer plies 4, second outer plies 5 also can adopt other raw material substitution Ganoderma spore powders, perhaps outside second outer plies again other raw materials of bag pressure also can.

Claims (6)

1. the Cordyceps sheet is characterized in that: be made up of two-layer at least lamella; Wherein, at least one synusia layer gets for Cordyceps pulverizing back preparation, and at least one synusia layer pulverizes the back for tonic or extraction active component preparation wherein gets.
2. Cordyceps sheet according to claim 1 is characterized in that: above lower leaf between the lamella.
3. Cordyceps sheet according to claim 1 is characterized in that: between the lamella with inside and outside layering.
4. according to each described Cordyceps sheet of claim 1-3, it is characterized in that: it is that 1~150 μ m, control powder moisture are 5~18% that Cordyceps is crushed to particle diameter.
5. Cordyceps sheet according to claim 4 is characterized in that: it is that 1~50 μ m, control powder moisture are 8~18% that Cordyceps is crushed to particle diameter.
6. according to each described Cordyceps sheet of claim 1-3, it is characterized in that: described tonic is a Radix Ginseng, Radix Panacis Quinquefolii, Radix Codonopsis, Radix Pseudostellariae, Rhizoma Polygonati, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Seem Lablab Album, Fructus Jujubae, Radix Glycyrrhizae, maltose, Cornu Cervi Pantotrichum, Cornu Cervi, Colla cornus cervi, Herba Epimedii, Rhizoma Curculiginis, Radix Morindae Officinalis, Fructus Psoraleae, Semen Juglandis, Herba Cistanches, Fructus Alpiniae Oxyphyllae, Semen Cuscutae, Gecko, Herba Cynomorii, Semen Trigonellae, Fructus Cnidii, Rhizoma Drynariae, Testis et penis callorhini, Radix Dipsaci, the Cortex Eucommiae, Rhizoma Cibotii, Radix Rehmanniae Preparata, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Colla Corii Asini, Fructus Mori, Arillus Longan, Radix Adenophorae (Radix Glehniae), Radix Asparagi, Radix Ophiopogonis, Herba Dendrobii, Rhizoma Polygonati Odorati, Bulbus Lilii, Fructus Lycii, Fructus Ligustri Lucidi, Herba Ecliptae, Carapax et Plastrum Testudinis, Colla Plastri Testudinis, Carapax Trionycis, Colla carapax Trionycis, Herba Taxilli, Ganoderma spore, in the Radix Astragali any one.
CN2009203038170U 2009-05-31 2009-05-31 Cordyceps sinensis tablet Expired - Lifetime CN201492711U (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102302671A (en) * 2011-09-20 2012-01-04 叶立新 Traditional Chinese medicine composition for treating impotence and preparation method thereof
CN102349975A (en) * 2011-10-11 2012-02-15 杭州天目山药业股份有限公司 Health care product formula of dendrobium officinale, composition as well as preparation method and application of composition
CN103271953A (en) * 2013-06-26 2013-09-04 通化臻尊生物科技有限公司 Preparation method of high-hardness cordyceps sinensis pure powder tablet
CN104382023A (en) * 2014-11-12 2015-03-04 郑海鸿 Food suitable for aged people and preparation method of food
CN104886558A (en) * 2015-05-06 2015-09-09 山东东阿阿胶股份有限公司 Donkey hide gelatin and pilose antler two-component tablet and preparation method
CN105361173A (en) * 2015-12-14 2016-03-02 梁文成 Bighead atractylodes rhizome cordyceps sinensis buccal tablets and making method thereof
CN105361044A (en) * 2015-12-14 2016-03-02 梁文成 Chinese yam cordyceps sinensis buccal tablets and making method thereof
CN105477050A (en) * 2015-12-14 2016-04-13 梁文成 Radix glycyrrhizae-cordyceps sinensis lozenge and preparation method thereof
CN105919954A (en) * 2016-06-08 2016-09-07 海南华益泰康药业有限公司 Preparation method of compound tablet containing ophiocordyceps sinensis and panax quinquefoliu
CN105998099A (en) * 2016-05-19 2016-10-12 青海悦真生物科技有限公司 Cordyceps sinensis buccal tablet and preparation method thereof

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102302671A (en) * 2011-09-20 2012-01-04 叶立新 Traditional Chinese medicine composition for treating impotence and preparation method thereof
CN102349975A (en) * 2011-10-11 2012-02-15 杭州天目山药业股份有限公司 Health care product formula of dendrobium officinale, composition as well as preparation method and application of composition
CN102349975B (en) * 2011-10-11 2015-05-20 杭州天目山药业股份有限公司 Health care product formula of dendrobium officinale, composition as well as preparation method and application of composition
CN103271953A (en) * 2013-06-26 2013-09-04 通化臻尊生物科技有限公司 Preparation method of high-hardness cordyceps sinensis pure powder tablet
CN104382023A (en) * 2014-11-12 2015-03-04 郑海鸿 Food suitable for aged people and preparation method of food
CN104886558A (en) * 2015-05-06 2015-09-09 山东东阿阿胶股份有限公司 Donkey hide gelatin and pilose antler two-component tablet and preparation method
CN105361173A (en) * 2015-12-14 2016-03-02 梁文成 Bighead atractylodes rhizome cordyceps sinensis buccal tablets and making method thereof
CN105361044A (en) * 2015-12-14 2016-03-02 梁文成 Chinese yam cordyceps sinensis buccal tablets and making method thereof
CN105477050A (en) * 2015-12-14 2016-04-13 梁文成 Radix glycyrrhizae-cordyceps sinensis lozenge and preparation method thereof
CN105998099A (en) * 2016-05-19 2016-10-12 青海悦真生物科技有限公司 Cordyceps sinensis buccal tablet and preparation method thereof
CN105919954A (en) * 2016-06-08 2016-09-07 海南华益泰康药业有限公司 Preparation method of compound tablet containing ophiocordyceps sinensis and panax quinquefoliu
CN105919954B (en) * 2016-06-08 2018-12-25 海南华益泰康药业有限公司 A kind of preparation method of the composite tablet containing cordyceps sinensis and American ginseng

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Legal Events

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C14 Grant of patent or utility model
GR01 Patent grant
PE01 Entry into force of the registration of the contract for pledge of patent right

Denomination of utility model: Cordyceps militaris tablet and preparation method thereof

Effective date of registration: 20110505

Granted publication date: 20100602

Pledgee: QINGHAI CHUNTIAN MEDICAL RESOURCE TECHNOLOGY UTILIZATION CO., LTD.

Pledgor: Zhang Xuefeng

Registration number: 2011990000163

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Date of cancellation: 20130107

Granted publication date: 20100602

Pledgee: QINGHAI CHUNTIAN MEDICAL RESOURCE TECHNOLOGY UTILIZATION CO., LTD.

Pledgor: Zhang Xuefeng

Registration number: 2011990000163

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Owner name: XIZANG RONGEN TECHNOLGY CO., LTD.

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Address after: The 850000 Tibet autonomous region Lhasa Boda District Economic and Technological Development Zone Road, B district two unit no. 4-1

Patentee after: Tibet grace Technology Co., Ltd.

Address before: 610016, No. 1, building 3, 85 Confucious'Temple Street, Qingyang District, Sichuan, Chengdu, 1

Patentee before: Zhang Xuefeng

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Patentee after: QINGHAI CHUNTIAN MEDICAL RESOURCE TECHNOLOGY UTILIZATION CO., LTD.

Address before: The 850000 Tibet autonomous region Lhasa Boda District Economic and Technological Development Zone Road, B district two unit no. 4-1

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