CN201131816Y - Multifunctional experimental operation platform - Google Patents
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- CN201131816Y CN201131816Y CNU2007201905726U CN200720190572U CN201131816Y CN 201131816 Y CN201131816 Y CN 201131816Y CN U2007201905726 U CNU2007201905726 U CN U2007201905726U CN 200720190572 U CN200720190572 U CN 200720190572U CN 201131816 Y CN201131816 Y CN 201131816Y
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Abstract
本实用新型涉及一种多功能实验操作平台,用于在实验动物的手术、核磁共振、CT等实验中对动物进行固定。包括有固定板、由工程塑料制成的立柱(2)、耳杆(3)、立柱(4)和固定动物牙齿齿环(5)。在固定板(1)的右端设置有两个第一凹槽(11),在每个第一凹槽(11)内都固定有固定动物头的立柱(2)。立柱(2)的位置能够相对于固定板上下移动,在每根立柱(2)的顶端都设置有能够相对于立柱(2)移动的耳杆(3)。在两个第一凹槽(11)的前端中心位置设置有立柱(4),在固定牙齿立柱(4)的顶端设置有固定动物牙齿齿环(5)。本实验台能够实现对动物稳妥固定、精确定位,以便于各项实验指标的无失真的观测。
The utility model relates to a multifunctional experimental operation platform, which is used for fixing animals in experiments such as operation, nuclear magnetic resonance and CT of experimental animals. The utility model comprises a fixing plate, a column (2) made of engineering plastics, an ear bar (3), a column (4) and a tooth ring (5) for fixing animal teeth. Two first grooves (11) are arranged on the right end of the fixing plate (1), and a column (2) for fixing the animal head is fixed in each first groove (11). The position of the column (2) can move up and down relative to the fixed plate, and an ear bar (3) capable of moving relative to the column (2) is arranged on the top of each column (2). An upright post (4) is arranged at the center positions of the front ends of the two first grooves (11), and a fixed animal tooth ring (5) is arranged on the top of the fixed tooth upright post (4). This experimental platform can realize stable fixation and precise positioning of animals, so as to facilitate the undistorted observation of various experimental indicators.
Description
技术领域 technical field
本实用新型涉及一种多功能实验操作平台,用于在实验动物的手术、立体定向给药、PET、核磁共振、CT、电生理检测等需固定动物的实验研究中对动物进行固定。The utility model relates to a multifunctional experimental operation platform, which is used for fixing animals in experimental researches such as operation of experimental animals, stereotaxic drug administration, PET, nuclear magnetic resonance, CT, electrophysiological detection and the like.
背景技术 Background technique
目前,科研常用的动物操作台结构简单,动物固定不稳定,无法实现动物的精确定位;多种手术操作、不同途径的给药和各种生理检测也不能在同一平台的实现;尤其是现用操作台多采用金属材料制作,在进行PET、核磁共振、CT等影像学检测时对实验产生严重干扰,影响实验结果的准确性和科学性。例如现固定实验大鼠多采用一20×30cm2、厚约1cm的木板周围相隔一定距离钉上数量不等铁钉作为绑定动物四肢之用,另用一横过木板头端的棉绳作为固定动物门齿之用,往往固定不稳妥、定位不准,也无法完成电生理、影像学检测。At present, the animal operating table commonly used in scientific research has a simple structure, and the animal is not fixed and unstable, so it is impossible to realize the precise positioning of the animal; various surgical operations, different routes of drug administration and various physiological tests cannot be realized on the same platform; The operating table is mostly made of metal materials, which seriously interferes with the experiment when performing imaging tests such as PET, nuclear magnetic resonance, and CT, and affects the accuracy and scientificity of the experimental results. For example, currently immobilized experimental rats usually use a 20×30cm 2 , 1cm thick wooden board with different numbers of iron nails at a certain distance around it to bind the limbs of the animal, and a cotton rope across the head of the wooden board as a fixation. Animal incisors are often not fixed securely, positioned inaccurately, and electrophysiological and imaging tests cannot be completed.
实用新型内容Utility model content
本实用新型的目的在于克服了现有操作台的上述缺陷,提供了一种多功能实验操作平台。在用不同实验动物完成各种手术操作、不同途径的给药、PET、核磁共振、CT、电生理检测等实验操作时,本实验台能够实现对动物稳妥固定、精确定位,以便于各项实验指标的无失真的观测,为实验创造良好的操作平台。The purpose of the utility model is to overcome the above-mentioned defects of the existing operating platform and provide a multifunctional experimental operating platform. When different experimental animals are used to complete various surgical operations, different routes of drug administration, PET, nuclear magnetic resonance, CT, electrophysiological detection and other experimental operations, this experimental table can realize stable fixation and precise positioning of animals, so as to facilitate various experiments The undistorted observation of indicators creates a good operating platform for experiments.
为了实现上述目的,本实用新型采取了如下技术方案。包括有固定板、由工程塑料制成的固定动物头的立柱、固定动物头的耳杆、固定动物牙齿立柱和固定动物牙齿齿环。所述的固定板为由工程塑料制成的固定板,在固定板的左端设置有用于固定动物腿的固定螺钉。其中,在固定板的右端沿中心线对称设置有两个第一凹槽,在每个第一凹槽内都固定有固定动物头的立柱,固定动物头的立柱的位置能够相对于固定板上下调节、沿着第一凹槽左右移动。固定动物头的立柱的位置能够相对于固定板上下移动,在每根固定动物头的立柱的顶端都设置有能够相对于固定动物头的立柱移动的固定动物头的耳杆。在两个第一凹槽的前端中心位置设置有能够相对于固定板上下移动的固定动物牙齿立柱,在固定牙齿立柱的顶端设置有能够相对于固定牙齿立柱相对移动的固定动物牙齿齿环。In order to achieve the above object, the utility model adopts the following technical solutions. The utility model comprises a fixing plate, a column for fixing the animal head made of engineering plastics, an ear bar for fixing the animal head, a column for fixing the animal teeth and a tooth ring for fixing the animal teeth. The fixing plate is a fixing plate made of engineering plastics, and a fixing screw for fixing the animal legs is arranged on the left end of the fixing plate. Wherein, two first grooves are arranged symmetrically along the center line on the right end of the fixing plate, and a column for fixing the animal head is fixed in each first groove, and the position of the column for fixing the animal head can be up and down relative to the fixing plate. To adjust, move left and right along the first groove. The position of the column for fixing the animal head can move up and down relative to the fixed plate, and the ear bar for fixing the animal head that can move relative to the column for fixing the animal head is provided at the top of each column for fixing the animal head. A fixed animal tooth column that can move up and down relative to the fixed plate is provided at the front center of the two first grooves, and a fixed animal tooth ring that can move relative to the fixed tooth column is provided at the top of the fixed tooth column.
在固定动物头的立柱和固定动物牙齿立柱之间设置有两根相对于固定板的位置能够上下调节并可与固定板固定连接的动物上颌固定立柱,动物上颌固定杆穿过两根动物上颌固定立柱的顶端。Between the column for fixing the head of the animal and the column for fixing the teeth of the animal, there are two animal upper jaw fixed columns that can be adjusted up and down relative to the fixed plate and fixedly connected with the fixed plate, and the animal upper jaw fixed rod passes through the two animal upper jaws The top of the column.
在两个第一凹槽之间还设置有用于放置标尺的第二凹槽,标尺在实验中可以用来测量动物头的尺寸。A second groove for placing a scale is also provided between the two first grooves, and the scale can be used to measure the size of the head of the animal in the experiment.
本实验台适用于鼠、兔、猫、猴子、狗、羊、猪等的固定,与现有实验台相比有以下优点:This experimental bench is suitable for fixing rats, rabbits, cats, monkeys, dogs, sheep, pigs, etc. Compared with the existing experimental benches, it has the following advantages:
1)设计科学合理,原理简单,易复制,固定动物牢固,不会产生松动,实用性较高。1) The design is scientific and reasonable, the principle is simple, easy to replicate, the animal is firmly fixed, no loosening occurs, and the practicability is high.
2)考虑到实验中常需要应用CT、MRI、PET等对动物进行观察,本实验台的各个部件选用高强度的工程塑料作为制作材料,因此动物操作平台无磁性和也不造成影像伪影。2) Considering that CT, MRI, PET, etc. are often used in experiments to observe animals, each part of this experimental platform is made of high-strength engineering plastics, so the animal operating platform is non-magnetic and does not cause image artifacts.
3)由于本实验台的各个立柱的高度可调,所以适用于对不同大小的动物进行固定,应用广泛。由于本实验台能够对动物头部的不同部位进行固定,所以本实验台能够满足各种手术的需要,能满足各类医院进行各类手术的操作训练,既适用于骨骼和开颅手术,又适于显微镜下精细操作。3) Since the height of each upright column of the experimental bench is adjustable, it is suitable for fixing animals of different sizes and is widely used. Because this experimental table can fix different parts of the animal's head, this experimental table can meet the needs of various operations, and can meet the operation training of various types of operations in various hospitals. It is not only suitable for bone and craniotomy operations, but also Suitable for fine manipulation under a microscope.
4)与标尺配合使用,可实现动物的精确定位,便于实施动物脑的立体定向给药。4) Used in conjunction with the ruler, it can realize the precise positioning of the animal and facilitate the implementation of stereotaxic administration of the animal brain.
5)固定装置可以调动,适用于头型不同大小的动物固定。5) The fixing device can be adjusted, which is suitable for fixing animals with different head shapes.
6)取材优良,费用低廉,重量轻,便于携带,不会生锈及变型,操作简便。6) The material is excellent, low in cost, light in weight, easy to carry, will not rust and deform, and is easy to operate.
附图说明 Description of drawings
图1多功能实验动物操作台侧视图Fig. 1 Side view of the multi-functional experimental animal operating table
图2多功能实验动物操作台俯视图Figure 2 The top view of the multifunctional experimental animal operating platform
图3固定板平面图Figure 3 Plane view of the fixed plate
图中:1、固定板,2、固定动物头的立柱,3、固定动物头的耳杆,4、固定动物牙齿立柱,5、固定动物牙齿齿环,6、动物上颌固定立柱,7、动物上颌固定杆,8、操作台腿,9、固定螺钉,10、螺母,11第一凹槽,12、第二凹槽。In the figure: 1. Fixed plate, 2. Upright post for fixing animal head, 3. Ear bar for fixing animal head, 4. Upright post for fixing animal tooth, 5. Ring for fixing animal tooth, 6. Upright post for fixing animal upper jaw, 7. Animal Maxillary fixed rod, 8, console leg, 9, fixing screw, 10, nut, 11 first groove, 12, second groove.
具体实施方式 Detailed ways
下面结合图1、图2详细说明本实施例。This embodiment will be described in detail below in conjunction with FIG. 1 and FIG. 2 .
如图1、图2所示,本操作台包括有固定板1、固定板、由工程塑料制成的固定动物头的立柱2、固定动物头的耳杆3、固定动物牙齿立柱4、固定动物牙齿齿环5、动物上颌固定立柱6、动物上颌固定杆7。在固定板1上靠近右端的位置沿固定板的中心线加工有第二凹槽12,该凹槽可以用来放置标尺,在实验中可以用来测量动物头的尺寸。在凹槽的两侧对称加工有两个第一凹槽11,固定动物头的立柱2可以穿过该凹槽并沿着凹槽左右移动,立柱2也可以相对于固定板1上下移动,当位置适中后通过螺母10将其固定在固定板1上。在立柱2上有一螺孔,耳杆3的一端加工有螺纹,通过螺纹配合是螺杆3可以相对于立柱2相对移动。As shown in Figure 1 and Figure 2, the console includes a
在固定板的左端设置有用于固定动物腿7对固定螺钉9,固定螺钉9由工程塑料制成。在实验中,将固定动物腿的绳固定在固定螺钉9上。The left end of the fixing plate is provided with 7 pairs of fixing screws 9 for fixing the animal legs, and the fixing screws 9 are made of engineering plastics. In the experiment, the rope that fixes the animal's leg is fixed on the set screw 9.
在立柱2的右端设置有一根固定动物牙齿立柱4,动物牙齿的立柱4相对于固定板1也可以上下移动,位置适中后通过螺母10将其固定在固定板1上。固定动物牙齿齿环5通过其一端的螺纹手柄与立柱4的上端的螺纹孔相连接,通过手柄的移动来调整牙齿齿环5的位置。The right-hand end of column 2 is provided with a fixed
在固定动物头的立柱2和固定动物牙齿立柱4之间设置有两根动物上颌固定立柱6,动物上颌固定立柱6通过螺栓10与固定板1固定连接,其相对于固定板1的位置可调。动物上颌固定杆7穿过两根动物上颌固定立柱6的顶端。Two animal maxillary
本实施例中的第一凹槽11、第二凹槽12均为贯通固定板的通孔,立柱穿过通孔通过螺栓与固定板1固定连接。In this embodiment, the
考虑到实验中可能需要应用CT、MRI、PET等对动物进行观察,因此要求材料无磁性和不造成影像伪影,本实施例中操作台的所有部件都是选用高强度的有机玻璃板、有机玻璃棒和尼龙棒等工程塑料作为制作材料。Considering that the animals may need to be observed by CT, MRI, PET, etc. in the experiment, it is required that the material is non-magnetic and does not cause image artifacts. Engineering plastics such as glass rods and nylon rods are used as manufacturing materials.
本实施例是按如下方法制作的:This embodiment is made as follows:
1)固定板1制做:综合考虑不同大小实验动物的操作需要,确定固定板1的尺寸。1) Manufacture of the fixing plate 1: the size of the
采用一定厚度的有机玻璃板,按设计大小切割成型,打磨处理板的各边及四角,使其光滑圆润,呈长方形结构。于固定板一端的中间,做一长槽12,于长槽的两侧,做两个对称的槽11,做成具有一定坡度的槽。槽11作为放置固定动物头可活动立柱2部位,可据动物头颅大小调整前后位置。中间的槽12作为测量动物头外形数据放置标尺的通道。于板中间长槽的顶端做一圆孔,备放置固定动物牙齿的立柱4用。于固定板两侧的槽11与近中间槽12之间的前方,各做一圆孔,作为固定上颌固定杆(门齿杠)立柱6的部位。于固定板1的两侧,做十四个对称的螺孔,作为铆定固定动物腿的螺钉用。于固定板1背面做六个对称盲孔,用于操作台六个腿的固定。如图中1。Use a certain thickness of plexiglass plate, cut and shape according to the designed size, and polish the sides and corners of the plate to make it smooth and round, with a rectangular structure. In the middle of one end of the fixed plate, a
2)固定动物头的立柱2及耳杆3的制做:取两根设计长度和直径的有机玻璃棒做立柱2,立柱2的一端做成螺栓,可据动物头颅大小调整高度;于立柱2的另一端距顶端一定距离做一螺母孔。另取两根有机玻璃棒做耳杆3,将耳杆3的一端制成与前述螺孔相匹配的螺拴,可据动物头颅大小调整两耳杆之间距离;将耳杆的的另一端削成细长圆锥体便于伸入动物耳孔妥贴固定动物头颅,尖端磨钝以免刺伤动物组织。将耳杆固定于立柱的螺母内,用于固定动物的头。如图中2、3。2) The production of the column 2 and the ear bar 3 for fixing the animal head: take two plexiglass rods of designed length and diameter to make the column 2, and one end of the column 2 is made into a bolt, and the height can be adjusted according to the size of the animal head; Make a nut hole at a certain distance from the top at the other end. Another two plexiglass rods are taken as ear rods 3, and one end of the ear rods 3 is made into a bolt matching the aforementioned screw hole, and the distance between the two ear rods can be adjusted according to the size of the animal head; the other end of the ear rods It is cut into a slender cone so that it can be inserted into the ear hole of the animal to fix the animal's head properly, and the tip is blunted to avoid stabbing the animal tissue. Fix the ear rods in the nuts of the uprights to hold the animal's head. As shown in Figure 2, 3.
3)固定动物牙齿的立柱4及齿环5的制做:取两根设计长度和直径的有机玻璃棒做立柱4,立柱4的一端做成螺栓,可据动物头颅大小调整高度;于立柱4的另一端距顶端一定距离做一螺母孔,作为固定可移动牙齿固定环的部位,同时兼做测量动物头外形数据的参照。另取一根圆柱形尼龙棒做齿环的柄(如图中5),将柄的一端制成与前述螺孔相匹配的螺栓,有螺纹部分较长,便于跟据动物大小调节齿环的前后位置;将柄的的另一端同样制成螺栓,有螺纹部分较短。鉴于动物口腔和牙间距的差别较大,制做直径为大、中、小的齿环,便于跟据动物大小选用合适的齿环。在齿环的侧边做一螺孔与柄的短螺栓匹配。如图中4、5。3) Manufacture of the
4)固定动物上颌立柱6及固定杆7(门齿杠)的制做:取两根设计长度和直径的有机玻璃棒做立柱,立柱一端做成螺栓,可据动物头颅大小调整高度;于立柱的另一端距顶端一定距离做一圆孔。取一细长尼龙棒做成紧密通过立柱圆孔的固定杆(门齿杠)。通过同步调整两立柱6的高度使固定杆7既可与齿环结合使用固定动物上颌,又可降低高度单独作为门齿杆使用(门齿杆就是上颌固定杆),如图中6、7。4) The making of fixed animal
5)操作台腿的制做:取六根设计长度和直径的有机玻璃棒做操作台的腿,腿一端做成螺栓,与固定板下面的盲孔紧密结合;另一端制成帽状,平稳支撑固定板完成各种操作。如图中8。5) Manufacture of console legs: Take six plexiglass rods of designed length and diameter as the legs of the console, one end of the legs is made into a bolt, which is tightly combined with the blind hole under the fixing plate; the other end is made into a cap shape for stable support The fixed plate completes various operations. As shown in figure 8.
6)固定螺钉的制作:用有机玻璃棒制做螺钉,与固定板上两侧的螺孔结合。视动物大小选用固定动物的腿。如图中9。6) Production of fixing screws: Use plexiglass rods to make screws, and combine them with the screw holes on both sides of the fixing plate. Depending on the size of the animal, the legs of the immobilized animal are selected. As shown in Figure 9.
7)螺母的制作:用粗的尼龙棒制做螺母,用于固定立柱。如图中10。7) Production of nuts: Use thick nylon rods to make nuts to fix the columns. Figure 10.
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| CN102525653A (en) * | 2010-12-20 | 2012-07-04 | 马劼 | Experimental large animal craniocerebral knocking combined device and design method thereof |
| CN104510489A (en) * | 2015-01-12 | 2015-04-15 | 天津医科大学第二医院 | Device for PET-CT-MR image fusion and fixation of experimental animal |
| WO2015054959A1 (en) * | 2013-10-18 | 2015-04-23 | 苏州瑞派宁科技有限公司 | Small animal position fixer |
| CN106821535A (en) * | 2016-12-26 | 2017-06-13 | 深圳市龙岗中心医院 | A kind of adjustable white mouse autopsy table |
| CN107149508A (en) * | 2017-06-23 | 2017-09-12 | 佛山科学技术学院 | Toy tests fixed system |
| CN108042237A (en) * | 2018-01-31 | 2018-05-18 | 付永伟 | Rat oral cavity experimental operation table and its application method |
| CN108478305A (en) * | 2018-04-24 | 2018-09-04 | 安徽师范大学 | For the three-dimensional fixed adapter of mouse brain |
| CN109907856A (en) * | 2017-12-13 | 2019-06-21 | 深圳先进技术研究院 | Vltrasonic device and animal fixing device |
| WO2020191948A1 (en) * | 2019-03-22 | 2020-10-01 | 中国科学院深圳先进技术研究院 | Animal surgical table |
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| CN102525653A (en) * | 2010-12-20 | 2012-07-04 | 马劼 | Experimental large animal craniocerebral knocking combined device and design method thereof |
| WO2015054959A1 (en) * | 2013-10-18 | 2015-04-23 | 苏州瑞派宁科技有限公司 | Small animal position fixer |
| CN104546209A (en) * | 2013-10-18 | 2015-04-29 | 苏州瑞派宁科技有限公司 | Small animal positioning instrument |
| CN104546209B (en) * | 2013-10-18 | 2017-03-15 | 苏州瑞派宁科技有限公司 | A kind of toy position finder |
| CN104510489A (en) * | 2015-01-12 | 2015-04-15 | 天津医科大学第二医院 | Device for PET-CT-MR image fusion and fixation of experimental animal |
| CN106821535B (en) * | 2016-12-26 | 2018-02-02 | 深圳市龙岗中心医院 | A kind of adjustable white mouse autopsy table |
| CN106821535A (en) * | 2016-12-26 | 2017-06-13 | 深圳市龙岗中心医院 | A kind of adjustable white mouse autopsy table |
| CN107149508A (en) * | 2017-06-23 | 2017-09-12 | 佛山科学技术学院 | Toy tests fixed system |
| CN109907856A (en) * | 2017-12-13 | 2019-06-21 | 深圳先进技术研究院 | Vltrasonic device and animal fixing device |
| CN108042237A (en) * | 2018-01-31 | 2018-05-18 | 付永伟 | Rat oral cavity experimental operation table and its application method |
| CN108042237B (en) * | 2018-01-31 | 2019-09-13 | 连云港市第一人民医院 | Rat oral cavity experiment operating table and using method thereof |
| CN108478305A (en) * | 2018-04-24 | 2018-09-04 | 安徽师范大学 | For the three-dimensional fixed adapter of mouse brain |
| CN108478305B (en) * | 2018-04-24 | 2024-04-19 | 安徽师范大学 | Adapter for three-dimensional fixation of mouse brain |
| WO2020191948A1 (en) * | 2019-03-22 | 2020-10-01 | 中国科学院深圳先进技术研究院 | Animal surgical table |
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