CN108042237A - Rat oral cavity experimental operation table and its application method - Google Patents

Rat oral cavity experimental operation table and its application method Download PDF

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Publication number
CN108042237A
CN108042237A CN201810097069.9A CN201810097069A CN108042237A CN 108042237 A CN108042237 A CN 108042237A CN 201810097069 A CN201810097069 A CN 201810097069A CN 108042237 A CN108042237 A CN 108042237A
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CN
China
Prior art keywords
rat
fixing piece
tooth fixing
oral cavity
crossbeam
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Granted
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CN201810097069.9A
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Chinese (zh)
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CN108042237B (en
Inventor
付永伟
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First Peoples Hospital of Lianyungang
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Individual
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Priority to CN201810097069.9A priority Critical patent/CN108042237B/en
Publication of CN108042237A publication Critical patent/CN108042237A/en
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Publication of CN108042237B publication Critical patent/CN108042237B/en
Expired - Fee Related legal-status Critical Current
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D15/00Mouth openers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • A61D2003/003Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes
    • A61D2003/006Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means

Abstract

The invention belongs to medical experiment animal equipment technical fields, and in particular to rat oral cavity experimental operation table and its application method, including stage body, supporting rack, the first fixation kit, the second fixation kit and oral cavity fixing piece;Supporting rack includes crossbeam and is used to support the first longeron and the second longeron of crossbeam;Crossbeam is supported jointly by the top of the first longeron and the top of the second longeron;First fixation kit includes the first connecting pole and the second connecting pole;Second fixation kit includes the 3rd connecting pole and the 4th connecting pole;Oral cavity fixation kit includes upper tooth fixing piece and lower tooth fixing piece;Upper tooth fixing piece is connected to one end of stage body length direction, and closes on the first fixation kit, and one end distance of upper tooth fixing piece and stage body length direction can be adjusted;Lower tooth fixing piece is connected on crossbeam, and the distance between lower tooth fixing piece and crossbeam can be adjusted.It can effectively open rat oral cavity, and device is simple and convenient to operate.

Description

Rat oral cavity experimental operation table and its application method
Technical field
The invention belongs to medical experiment animal equipment technical fields, and in particular to rat oral cavity experimental operation table and its use Method.
Background technology
Rat is one of common experimental animal in medical animal experiment field, is often used to replicate in dentistry experiment The animal models such as periodontitis, periapical inflammation, dental fluorosis, candida albicans infection.However, in actual mechanical process, due to big Limbs are weak and limp after mouse anesthesia, and the oral cavity of rat is smaller in addition, and how effectively fixing rat and opening rat oral cavity becomes puzzlement behaviour Make a great problem of personnel.
Under present condition, using will simply be fixed on experimental operation table after rat anesthesia, a people is responsible for most experiments personnel Fixed rat head simultaneously pulls the upper and lower jaw opening oral cavity of rat, and another people carries out oral cavity experimental implementation, usually 2 people needed to cooperate Into time-consuming and laborious.Further, since depth of anesthesia and time control are undesirable, it is movable suddenly to be often present with rat in operating process Situation, seriously affect experimental implementation, there is no preferable solution method so far.
The content of the invention
In order to solve the above technical problems, the present invention provides rat oral cavity experimental operation table and its application method, device letter It is single, easy to operate.
To realize above-mentioned technical purpose, the technical solution adopted by the present invention is rat oral cavity experimental operation table, including platform Body, supporting rack, the first fixation kit, the second fixation kit and oral cavity fixing piece;Supporting rack includes crossbeam and is used to support The first longeron and the second longeron of crossbeam;The lower end of first longeron is installed on the one side of stage body width, under the second longeron End is installed on the opposite side of stage body width;Crossbeam is supported jointly by the top of the first longeron and the top of the second longeron;The One fixation kit includes the first connecting pole and the second connecting pole, and the first connecting pole and the second connecting pole are symmetrically set in stage body width side To both sides, and positioned at supporting rack one side;Second fixation kit includes the 3rd connecting pole and the 4th connecting pole, the 3rd connecting pole The both sides of stage body width are symmetrically set in the 4th connecting pole, and positioned at the opposite side of supporting rack;Oral cavity fixation kit includes Upper tooth fixing piece and lower tooth fixing piece;Upper tooth fixing piece is connected to one end of stage body length direction, and closes on the first fixation kit, One end distance of upper tooth fixing piece and stage body length direction can be adjusted;Lower tooth fixing piece is connected on crossbeam, and lower tooth fixing piece Distance between crossbeam can be adjusted.
As the improved technical solution of the present invention, distance is the second fixation kit and branch between the first fixation kit and supporting rack The 2/3-3/4 of distance between support.
As the improved technical solution of the present invention, the upper tooth fixing piece is annulus;The lower tooth fixing piece is line, line One end is commonly connected to the other end of line on crossbeam after passing through rat tongue body.
As the improved technical solution of the present invention, the crossbeam is equipped with mounting ring.
As the improved technical solution of the present invention, the upper tooth fixing piece includes the second preceding protrusion and is divided into the second lordosis Protrusion after the second of portion both sides, protrusion is connected with stage body after second;The lower tooth fixing piece includes the first preceding protrusion with being divided into Protrusion after the first of first preceding protrusion both sides, protrusion is connected with crossbeam after first, and the first preceding protrusion is to the side of rat cavity interior To arranged on elongated end, elongated end can form the space for accommodating rat tongue body with the rat upper jaw.
As the improved technical solution of the present invention, elongated end is corrugated surface in the one side contacted with rat tongue body.
As the improved technical solution of the present invention, the upper tooth fixing piece is connected to by filament on stage body;Stage body is in length The end for spending direction is equipped with screw, and filament is lain on screw.
As the improved technical solution of the present invention, upper tooth fixing piece is plastic cement material.
As the improved technical solution of the present invention, the top of the first longeron and the top of the second longeron are equipped with protrusion, horizontal Beam is equipped with groove in correspondence position, and crossbeam is installed on top and the second longeron of the first longeron by the cooperation of groove and protrusion Top.
It is a further object of the present invention to provide rat oral cavity experimental operation table application methods, include the following steps:
It is lain in respectively on the four limbs of rat Step 1: four connecting lines are respectively adopted, the connection on one foreleg of rat will be connected to Linear system is on the first connecting pole, after the connecting line that is connected on another foreleg of rat lies in the second connecting pole, is connected to rat one The connecting line that connecting line on leg lies in the 3rd connecting pole, is connected on another back leg of rat lies in the 4th connecting pole;
Step 2: lower tooth fixing piece is fixed the lower tooth of rat and rat tongue body, upper tooth fixing piece fixes rat upper teeth, adjusts The filament of the upper tooth fixing piece of section connection and the line for adjusting connection lower tooth fixing piece, ensure that the oral cavity of rat is opened completely.
Advantageous effect
The experimental operation table of the application can easily and effectively fix rat four limbs and head and open rat oral cavity, make various oral cavities Operation can efficiently, be smoothed out, laboratory technician can be facilitated individually operated.
The application experimental operation table is simple in structure, easy to operate, at low cost, ease of assembly, suitable for all kinds of size rats Oral cavity experiment, and it overcomes that carry out experiment existing safety in oral cavity after direct anesthetized rat in the prior art to rat hidden Suffer from(After such as anaesthetizing failure, mouse aggravating activities causes experimenter to accidentally injure).
Description of the drawings
The structure diagram of Fig. 1 the application experimental operation tables;
The decomposed structure diagram of Fig. 2 the application experimental operation tables;
The structure diagram of upper tooth fixing piece in Fig. 3 the application experimental operation tables;
In figure, 1, stage body;2nd, the first longeron;3rd, the 3rd connecting pole;4th, connecting line;5th, the 4th connecting pole;6th, connecting line;7th, spiral shell Nail;8th, upper tooth fixing piece;9th, lower tooth fixing piece;10th, the second longeron top;11st, the side protrusion of the first longeron;12nd, mounting groove; 91st, the first preceding protrusion;92nd, protrusion after first.
Specific embodiment
To make the purpose of the embodiment of the present application and technical solution clearer, below in conjunction with the embodiment of the present application to this Shen Technical solution please is clearly and completely described.Obviously, described embodiment is the part of the embodiment of the application, and The embodiment being not all of.Based on described embodiments herein, those of ordinary skill in the art are without creative labor All other embodiments obtained on the premise of dynamic, shall fall in the protection scope of this application.
Those skilled in the art of the present technique are appreciated that unless otherwise defined, all terms used herein(Including technology art Language and scientific terminology)With the identical meaning of the general understanding with the those of ordinary skill in the application fields.Should also Understand, those terms such as defined in the general dictionary, which should be understood that, to be had and the meaning in the context of the prior art The consistent meaning of justice, and unless defined as here, will not be with idealizing or the meaning of overly formal be explained.
The meaning of " connection " described herein can be between component to be directly connected to can also pass through between component Other components are indirectly connected with.
Rat oral cavity as shown in Figure 1 experimental operation table, including stage body 1, supporting rack, the first fixation kit, the second fixation group Part and oral cavity fixing piece;
Supporting rack includes crossbeam and is used to support the first longeron 2 and the second longeron of crossbeam;The lower end of first longeron 2 is installed on The one side of 1 width of stage body, the lower end of the second longeron are installed on the opposite side of 1 width of stage body(During practical application, first The lower end of 2 and second longeron of longeron is installed on by " Tenon " structure on stage body 1);Crossbeam is by the top and second of the first longeron 2 The top of longeron supports jointly;
First fixation kit includes the first connecting pole and the second connecting pole, and the first connecting pole and the second connecting pole are symmetrically set in stage body The both sides of 1 width, and positioned at the one side of supporting rack;
Second fixation kit includes the 3rd connecting pole 3 and the 4th connecting pole 5, and the 3rd connecting pole 3 is symmetrically set in the 4th connecting pole 5 The both sides of 1 width of stage body, and positioned at the opposite side of supporting rack;(In actual use, the first connecting pole, the second connecting pole, Three connecting poles 3 and the 4th connecting pole 5 are screw 7)
Oral cavity fixation kit includes upper tooth fixing piece 8 and lower tooth fixing piece 9;Upper tooth fixing piece 8 is connected to 1 length direction of stage body One end, and the first fixation kit is closed on, one end distance of upper tooth fixing piece 8 and 1 length direction of stage body can be adjusted;Lower tooth fixing piece 9 It is connected on crossbeam, and the distance between lower tooth fixing piece 9 and crossbeam can be adjusted.
Embodiment 1, the top of the first longeron 2 is equipped with protrusion with the second longeron top 10 in the present embodiment, and crossbeam is right Position is answered to be equipped with groove, crossbeam is installed on the top and the second longeron top 10 of the first longeron 2 by the cooperation of groove and protrusion, As shown in Figure 2;The two sides of stage body 1 are equipped with mounting groove 12 simultaneously, and the side of the first longeron 2 is equipped with side protrusion, the first longeron Side protrusion 11 be installed in mounting groove 12, the side of the second longeron is equipped with side protrusion, and the side protrusion of the second longeron is installed on In tankage.
In order to enable rat four limbs can be pulled open uniformly in experiment, distance is solid for second between the first fixation kit and supporting rack Determine the 2/3-3/4 of distance between component and supporting rack, and the first fixation kit closes on oral cavity fixation kit;Concrete application example is tested Operation console specification is as follows:Stage body 1 is made of wooden boards, long 550mm, wide 300mm, thick 15mm;The screw 7 at 1 top of stage body Central point positioned at 1 top of stage body, 1 both sides front end iron nail of stage body are located at 1 top 100mm of stage body, 1 both sides rear end of stage body Screw is located at 1 bottom 100mm of stage body;First longeron 2 and the second longeron are wooden boards, long 20mm, width 15mm, High 150mm, the first longeron 2 are connected with the lower end of the second longeron by " Tenon " structure with stage body 1, and are located at respectively apart from stage body At 1 top 250mm;The crossbeam of 1 top of stage body is wooden boards, and long 300mm, width 20mm, high 15mm, both ends are fixed by iron nail In the first longeron 2 of 1 both sides of stage body and the top of the second longeron, crossbeam is apart from the about 150mm of stage body 1;Cord, filament and connection Cotton cotton rope can be used in line 64.
Embodiment 2, as shown in Figs. 1-2, upper tooth fixing piece 8 is annulus described in the present embodiment;The lower tooth fixing piece 9 is Annulus, in order to facilitate the tooth of oral cavity fixation kit fitting rat, annulus is plastic cement material, the main toughness for utilizing plastic cement material With tensile resistance.The upper tooth fixing piece 8 is annulus.The lower tooth fixing piece 9 is line, by round needle band line by line during use It is connected on crossbeam, particularly one end of line after passing through 1/3 in rat tongue body with the other end of line is held in and is connected jointly In the filament on crossbeam.Round needle is through at rat tongue 1/3 during use, at the same pull lower jaw backward on, fixed by needle holder In on filament, further, the crossbeam is equipped with mounting ring, and filament is connected in mounting ring.
Embodiment 3, as shown in figure 3, the upper tooth fixing piece 8 includes the second preceding protrusion and is divided into the second preceding protrusion both sides Second after protrusion, protrusion is connected with stage body 1 after second;The lower tooth fixing piece 9 includes the first preceding protrusion 91 and is divided into the Protrusion 92 after the first of one preceding 91 both sides of protrusion, protrusion 92 is connected with crossbeam after first, and the first preceding protrusion 91 is into rat oral cavity The direction in portion is arranged on elongated end;Elongated end forms a space with Rat Mandibular during use, and rat tongue is then defined and the space In, the upper tooth of rat is then fixed in the first preceding protrusion 91.Preferably, the upper tooth fixing piece 8 is connected to by filament on stage body 1; Stage body 1 is equipped with screw 7 in the end of length direction, and filament is lain on screw 7;The lower tooth fixing piece 9 is connected to by filament On crossbeam;Crossbeam is equipped with mounting ring, and filament is connected in mounting ring;Preferably, upper tooth fixing piece 8 be plastic cement material, lower tooth Fixing piece 9 is plastic cement material.It is further preferred that elongated end is non slip surface in the face contacted with rat tongue body, it is specific anti-skidding Face is chosen as corrugated surface or scribbles nonskid coating.
Nonskid coating includes each substance of following parts by weight:
20-130 parts of silica
10-30 parts of glass microballoon
30-50 parts of resin
30-50 parts of magnesium powder.
Particularly, after elongated end prepares shaping, uniformly mixed nonskid coating is pressed by the way of hot pressing The surface contacted with elongated end with tongue body.
The size of wherein silica is 100-1000 μm, the size of glass microballoon is 100-500 μm, the size of magnesium powder is 100-3000 microns.
Resin includes the one or more in epoxy resin, polyurethane, acrylic resin, PP resins, polyvinyl resin.
It can guarantee that each grain fraction can both can guarantee anti-skidding spy when in use on the premise of having resin using hot pressing Property can be stable in the presence of the surface of elongated end again.
Embodiment 4, in order to facilitate the dismounting and assembling of experimental operation table, the first longeron 2 and the second longeron pass through bolt It is installed on stage body 1, absent-mindedness bolt can realize the angle for adjusting supporting rack and stage body 1, facilitate the storage of experimental operation table.
In 5 the present embodiment of embodiment, the lower tooth fixing piece of rat is using filament, and filament is by rat tongue body and upper tooth Common fixed stretching is upward;Upper tooth fixing piece is using filament.
It is a further object of the present invention to provide rat oral cavity experimental operation table application methods, include the following steps:
It is lain in respectively on the four limbs of rat Step 1: four connecting lines are respectively adopted, the connection on one foreleg of rat will be connected to Linear system is on the first connecting pole, after the connecting line that is connected on another foreleg of rat lies in the second connecting pole, is connected to rat one The connecting line that connecting line on leg lies in the 3rd connecting pole, is connected on another back leg of rat lies in the 4th connecting pole;
Step 2: upper tooth fixing piece 8 is fixed rat upper teeth, lower tooth fixing piece 9 fixes lower teeth and the rat of rat Tongue adjusts the filament of the upper tooth fixing piece 8 of connection(Connecting line 6)And adjust the line of connection lower tooth fixing piece 9(Filament), protect It opens completely in the oral cavity of card rat;And what be can guarantee by the process is that rat is to face upward to lie on testing stand.
The iron nail that the program passes through 1 both sides of experimental operation table stage body and top in actual use(Each side two, top One, portion is the first connecting pole, the second connecting pole, the 3rd connecting pole 3, the 4th connecting pole 5 and screw 7)Using connecting line 6 (Cord)Fixed rat four limbs and head, make postanesthetic rat into dorsal position;
The line of drawing lower tooth fixing piece 9, fixed rat tongue body and lower jaw are fixed by the crossbeam above experimental operation table simultaneously, it can Effectively open rat oral cavity.
It is obvious to a person skilled in the art that the application is not limited to the details of above-mentioned exemplary embodiment, Er Qie In the case of without departing substantially from spirit herein or essential characteristic, the application can be realized in other specific forms.Therefore, no matter From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and scope of the present application is by appended power Profit requirement rather than above description limit, it is intended that all by what is fallen within the meaning and scope of the equivalent requirements of the claims Variation is included in the application.
Moreover, it will be appreciated that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should Using specification as an entirety, the technical solutions in each embodiment can also be properly combined, forms those skilled in the art It is appreciated that other embodiment.

Claims (10)

1. rat oral cavity experimental operation table, which is characterized in that including stage body, supporting rack, the first fixation kit, the second fixation group Part and oral cavity fixing piece;Supporting rack includes crossbeam and is used to support the first longeron and the second longeron of crossbeam;First longeron Lower end be installed on the one side of stage body width, the lower end of the second longeron is installed on the opposite side of stage body width;Crossbeam It is supported jointly by the top of the first longeron and the top of the second longeron;First fixation kit is connected including the first connecting pole with second Column, the first connecting pole and the second connecting pole are symmetrically set in the both sides of stage body width, and positioned at the one side of supporting rack;Second is solid Determining component includes the 3rd connecting pole and the 4th connecting pole, and the 3rd connecting pole and the 4th connecting pole are symmetrically set in stage body width Both sides, and positioned at the opposite side of supporting rack;Oral cavity fixation kit includes upper tooth fixing piece and lower tooth fixing piece;Upper tooth fixing piece connects One end of stage body length direction is connected to, and closes on the first fixation kit, one end distance of upper tooth fixing piece and stage body length direction It can adjust;Lower tooth fixing piece is connected on crossbeam, and the distance between lower tooth fixing piece and crossbeam can be adjusted.
2. rat oral cavity according to claim 1 experimental operation table, which is characterized in that between the first fixation kit and supporting rack The 2/3-3/4 of distance distance between the second fixation kit and supporting rack.
3. rat oral cavity according to claim 1 experimental operation table, which is characterized in that the upper tooth fixing piece is annulus; The lower tooth fixing piece is line, and one end of line is commonly connected to through the other end with line after rat tongue body on crossbeam.
4. the rat oral cavity experimental operation table according to claim 1 or 3, which is characterized in that the crossbeam is equipped with installation Ring.
5. rat oral cavity according to claim 1 experimental operation table, which is characterized in that the upper tooth fixing piece includes second Preceding protrusion and be divided into the second preceding protrusion both sides second after protrusion, protrusion is connected with stage body after second;The lower tooth fixing piece Including protrusion after first of the first preceding protrusion with being divided into the first preceding protrusion both sides, protrusion is connected with crossbeam after first, before first Protrusion is arranged on elongated end to the direction of rat cavity interior, and elongated end can form the space for accommodating rat tongue body with the rat upper jaw.
6. rat oral cavity according to claim 5 experimental operation table, which is characterized in that elongated end is contacted with rat tongue body One side be corrugated surface.
7. the rat oral cavity experimental operation table according to claim 1,3 or 5, which is characterized in that the upper tooth fixing piece leads to Filament is crossed to be connected on stage body;Stage body is equipped with screw in the end of length direction, and filament is lain on screw.
8. the rat oral cavity experimental operation table according to claim 1,3 or 5, which is characterized in that upper tooth fixing piece is plastic cement Material.
9. rat oral cavity according to claim 1 experimental operation table, which is characterized in that the top of the first longeron is vertical with second The top of beam is equipped with protrusion, and crossbeam is equipped with groove in correspondence position, and crossbeam is installed on first by the cooperation of groove and protrusion The top of longeron and the top of the second longeron.
10. the rat oral cavity experimental operation table application method as described in claim 1,2,3,5 or 9, which is characterized in that including such as Lower step:
It is lain in respectively on the four limbs of rat Step 1: four connecting lines are respectively adopted, the connection on one foreleg of rat will be connected to Linear system is on the first connecting pole, after the connecting line that is connected on another foreleg of rat lies in the second connecting pole, is connected to rat one The connecting line that connecting line on leg lies in the 3rd connecting pole, is connected on another back leg of rat lies in the 4th connecting pole;
Step 2: lower tooth fixing piece is fixed the lower tooth of rat and rat tongue body, upper tooth fixing piece fixes rat upper teeth, adjusts The filament of the upper tooth fixing piece of section connection and the line for adjusting connection lower tooth fixing piece, ensure that the oral cavity of rat is opened completely.
CN201810097069.9A 2018-01-31 2018-01-31 Rat oral cavity experimental operation table and its application method Expired - Fee Related CN108042237B (en)

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CN108042237B CN108042237B (en) 2019-09-13

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Cited By (2)

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Publication number Priority date Publication date Assignee Title
CN109172030A (en) * 2018-11-06 2019-01-11 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 A kind of experimental provision of mouse trachea cannula
CN113952073A (en) * 2021-12-08 2022-01-21 华中科技大学同济医学院附属协和医院 Mouth gag is fixed to toy tongue for experiments

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CN113952073A (en) * 2021-12-08 2022-01-21 华中科技大学同济医学院附属协和医院 Mouth gag is fixed to toy tongue for experiments
CN113952073B (en) * 2021-12-08 2023-08-15 华中科技大学同济医学院附属协和医院 Small animal tongue fixing mouth gag for experiments

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Effective date of registration: 20190812

Address after: 222061 No. 6 Zhenhua East Road, Haizhou District, Lianyungang City, Jiangsu Province

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