CN109172030A - A kind of experimental provision of mouse trachea cannula - Google Patents
A kind of experimental provision of mouse trachea cannula Download PDFInfo
- Publication number
- CN109172030A CN109172030A CN201811313826.8A CN201811313826A CN109172030A CN 109172030 A CN109172030 A CN 109172030A CN 201811313826 A CN201811313826 A CN 201811313826A CN 109172030 A CN109172030 A CN 109172030A
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- Prior art keywords
- mouse
- fixed frame
- trachea cannula
- pendulum
- experimental provision
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D15/00—Mouth openers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/003—Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/006—Appliances for supporting or fettering animals for operative purposes with leg or foot restraining means
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Husbandry (AREA)
- Eye Examination Apparatus (AREA)
Abstract
The invention discloses a kind of experimental provisions of mouse trachea cannula, including fixed frame, four limbs fixing piece and head mount on fixed frame are set, and light supply apparatus, the adjustable support for installing light supply apparatus is provided on fixed frame, the adjustable support is for adjusting light supply apparatus to mouse neck location, fixed frame includes that an opposite ground is tiltedly installed with placed side, four limbs fixing piece and head mount are arranged on placed side, head mount is an elastic string, the elastic string is for fixing mouse upper jaw front tooth, clip tongue device is additionally provided on fixed frame, clip tongue device is provided with flexible connecting rope, the connecting rope other end is connect with fixed frame, the clip tongue device is used to clamp the tongue of mouse, device provided by the invention can preferably fix mouse, play auxiliaring effect, quickly exposure mouse glottis.
Description
Technical field
The present invention relates to field of experiment equipment, further relate to a kind of experimental provision of mouse trachea cannula.
Background technique
With the needs of medical research, increasingly application is ground with the animal model for medical experiment for ventilator assisted ventilation techniques
Study carefully, quickly and effectively trachea cannula is the key that using one of ventilator assisted ventilation techniques.And large and small mouse be current use compared with
More experimental animals.Current large and small mouse oral trachea cannula method mainly has under tracheostomy tube method, blindmate method, direct-view
Intubation and Endoscope-assisted intubation etc..The frequency of use for especially looking at lower intubation straight is higher, and looking at lower intubation straight has
Success rate is high, exempts from the advantages that wound.Operator is close to large and small mouse neck using high-power incandescent lamp bulb or cold light source, by saturating
The light for crossing neck is aided with the large and small mouse root of the tongue of drawing, can expose glottis, to improve the success rate for looking at lower intubation straight.
In existing experimentation, it is by lying on table top in intubation for mouse, by holding flashlight
The light for penetrating neck is provided, and struts murine oral, to find glottis, but according to existing laboratory facilities, mouse due to
It lying on the back on the table, mouse cannot expose glottis well, in the prior art, without properly fixing the fixation device of mouse,
And the far and near of light source has a great impact to mouse exposure glottis, so that surgical procedure controllability is small, experimentation needs ripe
Experienced operation technique.
Summary of the invention
In view of the deficiencies of the prior art, the present invention intends to provide a kind of experiment dress of mouse trachea cannula
It sets, can preferably fix mouse, play auxiliaring effect, quickly exposure mouse glottis.
To achieve the above object, the present invention provides the following technical scheme that a kind of experimental provision of mouse trachea cannula, packet
It includes fixed frame, the four limbs fixing piece that is arranged on fixed frame and head mount and light supply apparatus, is arranged on the fixed frame
There is the adjustable support for installing light supply apparatus, which is used to adjust light supply apparatus to mouse neck location,
The fixed frame includes that an opposite ground is tiltedly installed with placed side, and the four limbs fixing piece is being put with head mount setting
It sets on face, the head mount is an elastic string, which also sets on the fixed frame for fixing mouse upper jaw front tooth
It is equipped with clip tongue device, the clip tongue device is provided with flexible connecting rope, which connect with fixed frame, the clip tongue
Device is used to clamp the tongue of mouse.
As a further improvement of the present invention, the light supply apparatus is cold light source.
As a further improvement of the present invention, the adjusting bracket includes linking arm, installing arm and mounting base, the company
It is hinged with fixed frame to connect arm, the installing arm and linking arm are hinged, and the linking arm and installing arm are in " 7 " font, the installation
The one end of installing arm far from linking arm is arranged in seat.
As a further improvement of the present invention, setting is there are four mounting groove on the fixed frame, shape between four mounting grooves
At one for placing the fixed bit of mouse, four four limbs fixing pieces are provided with flexural pivot, the flexural pivot and peace
Tankage is hinged, and the four limbs fixing piece includes clamping piece, and the clamping piece is for clamping mouse four limbs, the clamping piece and flexural pivot
Connector is movably hinged.
It as a further improvement of the present invention, further include having spigot joint, the spigot joint is for connecting insertion and exhales
The inner tubal wall of suction machine, the spigot joint is provided with pendulum, and the pendulum is flaky, the edge and intubation inner wall elasticity of the pendulum
Connection, the pendulum can follow air-flow to swing, and the spigot joint inner wall is provided with foil gauge, the foil gauge in pendulum two sides
It is connected with counter, forms a closure electrical circuit with counter when foil gauge and pendulum are mutually contradicted, counter starts to count
Number, connects the counter and is connected with relay.
As a further improvement of the present invention, it is provided with fixing sleeve in the elastic string, the fixing sleeve and elastic string are slided
Connection, the fixing sleeve are used to be socketed the tooth of mouse.
As a further improvement of the present invention, the clip tongue device is socketed with soft glue-line.
The invention has the benefit that by setting fixed frame, the four limbs of mouse are fixed on fixation by four limbs fixing piece
On the slant setting face of frame, mouse is arranged on placed side at suspension type, by the way that the elastic string of fixed frame upper end is arranged in, elasticity
Rope hook lives mouse upper tooth, and the upper jaw of mouse is pulled up, and lower jaw automatically opens, while unfolding the neck of mouse, passes through clip tongue
Tongue is fixed on a side outside oral cavity by device, and light supply apparatus is mounted on adjustable support, by adjusting adjustable by exposure glottis
It saves bracket and light supply apparatus is directed at mouse neck, and realize far and near adjusting, whole device is simple, can be good at fixing small
The posture of mouse, facilitates and is intubated.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of fixed frame of the present invention；
Fig. 2 is the structural schematic diagram of spigot joint of the present invention.
1, fixed frame；2, four limbs fixing piece；3, head mount；4, light supply apparatus；5, adjustable support；6, placed side；
7, clip tongue device；8, connecting rope；9, linking arm；10, installing arm；11, mounting base；12, flexural pivot；13, clamping piece；14, it is intubated
Connector；15, pendulum；16, foil gauge；17, counter；18, relay；19, fixing sleeve；20, soft glue-line；21, mounting groove.
Specific embodiment
The present invention is described in further detail below in conjunction with embodiment given by attached drawing.
Referring to Fig.1 shown in -2, a kind of portable clothes disclosed in the present embodiment one, including fixed frame 1, setting are on fixed frame 1
Four limbs fixing piece 2 and head mount 3 and light supply apparatus 4, be provided with for installing light supply apparatus 4 on the fixed frame 1
Adjustable support 5, for adjusting light supply apparatus 4 to mouse neck location, the fixed frame 1 includes the adjustable support 5
There is an opposite ground to be tiltedly installed with placed side 6, the four limbs fixing piece 2 is arranged on placed side 6 with head mount 3, institute
Stating head mount 3 is an elastic string, which is additionally provided with folder on the fixed frame 1 for fixing mouse upper jaw front tooth
Tongue device 7, the clip tongue device 7 are provided with flexible connecting rope 8, which connect with fixed frame 1, the clip tongue
Device 7 is used to clamp the tongue of mouse.
By the way that fixed frame 1 is arranged, the four limbs of mouse are fixed on the slant setting face 6 of fixed frame 1 by four limbs fixing piece 2
On, mouse is arranged on placed side 6 at suspension type, and by the way that the elastic string of 1 upper end of fixed frame is arranged in, elastic string is hooked on mouse
The upper jaw of mouse is pulled up by tooth, and lower jaw automatically opens, while unfolding the neck of mouse, is fixed tongue by clip tongue device 7
A side outside oral cavity, exposure glottis, light supply apparatus 4 is mounted on adjustable support 5, by adjusting adjustable support 5
Light supply apparatus 4 is directed at mouse neck, and realizes far and near adjusting, whole device is simple, can be good at the appearance of fixed mouse
Gesture facilitates and is intubated.
As a kind of improved specific embodiment, the light supply apparatus 4 is cold light source, to prevent light source close to mouse
It is scalded when skin.
As a kind of improved specific embodiment, the adjusting bracket includes linking arm 9, installing arm 10 and mounting base
11, the linking arm 9 and fixed frame 1 are hinged, and the installing arm 10 is hinged with linking arm 9, and the linking arm 9 is in installing arm 10
The one end of installing arm 10 far from linking arm 9 is arranged in " 7 " font, the mounting base 11, and mounting base 11 can be using clamping knot
Structure or fastening structure are rotatablely connected arm 9 and installing arm 10, change the claming angle and installing arm of linking arm 9 and fixed frame 1
10 change with the claming angle of linking arm 9 at a distance from the skin of light supply apparatus 4 and mouse neck.
As a kind of improved specific embodiment, there are four mounting groove 21, four mounting grooves for setting on the fixed frame 1
One is formed between 21 for placing the fixed bit of mouse, four four limbs fixing pieces 2 are provided with flexural pivot 12, the ball
Articulated joint 12 and mounting groove 21 are hinged, and the four limbs fixing piece 2 includes clamping piece 13, and the clamping piece 13 is for clamping mouse four
Limb, the clamping piece 13 is movably hinged with flexural pivot 12, by leading to four limbs fixing piece 2 and the mounting base 11 on fixed frame 1
The flexible connection of flexural pivot 12 is crossed, to adjust the distance between clamping piece 13 on four limbs fixing piece 2, to adapt to not homomorphs
Mouse, by the way that clamping piece 13 is flexibly connected with flexural pivot 12, preferably flexural pivot connect, with adjustment keep clamping piece 13
It keeps with placed side 6 in vertical state, the clamping piece 13 for being facilitates fixation when clamping mouse.
It further include having spigot joint 14 as a kind of improved specific embodiment, the spigot joint 14 is slotting for connecting
Pipe and ventilator, the inner tubal wall of the spigot joint 14 are provided with pendulum 15, and the pendulum 15 is flaky, the side of the pendulum 15
Edge can follow air-flow to swing with intubation inner wall elastic connection, the pendulum 15, and 14 inner wall of spigot joint is in 15 two sides of pendulum
It is provided with foil gauge 16, the foil gauge 16 is connected with counter 17, when foil gauge 16 and pendulum 15 mutually contradict and counts
Device 17 forms a closure electrical circuit, and counter 17 starts counting, connects the counter 17 and be connected with relay 18.
By the way that spigot joint 14 is arranged, pendulum 15 is set in spigot joint 14, to check whether intubation is accurately inserted into
Tracheae, when intubation is inserted into tracheae, mouse breathing will drive the swing of pendulum 15, and pendulum 15 connects when swinging with foil gauge 16
Touching, counter 17 receive the electric signal of foil gauge 16, count and monitoring frequency, the model of foil gauge 16 are selected KFW, counted
Device 17 preferably uses the counter 17 of M-7016-G CR model, and overall structure is simple, with higher sensitivity can be examined
Survey intubation insertion tracheae.
As a kind of improved specific embodiment, it is provided with fixing sleeve 19 in the elastic string, the fixing sleeve 19 and bullet
Property rope be slidably connected, which is used to be socketed the tooth of mouse, prevents stretch cord from causing to damage to murine oral mucous membrane.
As a kind of improved specific embodiment, the clip tongue device 7 is socketed with soft glue-line 20, and it is right to reduce clip tongue device 7
It is stimulated caused by mouse.
The above is only the preferred embodiment of the present invention, protection scope of the present invention is not limited merely to above-described embodiment,
All technical solutions belonged under thinking of the present invention all belong to the scope of protection of the present invention.It should be pointed out that for the art
For those of ordinary skill, several improvements and modifications without departing from the principles of the present invention, these improvements and modifications are also answered
It is considered as protection scope of the present invention.
Claims (7)
1. a kind of experimental provision of mouse trachea cannula, which is characterized in that including fixed frame (1), be arranged on fixed frame (1)
Four limbs fixing piece (2) and head mount (3) and light supply apparatus (4) are provided with for installing light on the fixed frame (1)
The adjustable support (5) of source device (4), the adjustable support (5) are used to adjust light supply apparatus (4) to mouse neck location,
The fixed frame (1) includes that an opposite ground is tiltedly installed with placed side (6), and the four limbs fixing piece (2) is fixed with head
Part (3) is arranged on placed side (6), and the head mount (3) is an elastic string, and the elastic string is for fixing mouse upper jaw door
Tooth is additionally provided with clip tongue device (7) on the fixed frame (1), and the clip tongue device (7) is provided with flexible connecting rope (8), should
Connecting rope (8) other end is connect with fixed frame (1), which is used to clamp the tongue of mouse.
2. a kind of experimental provision of mouse trachea cannula as described in claim 1, which is characterized in that the light supply apparatus (4)
For cold light source.
3. a kind of experimental provision of mouse trachea cannula as described in claim 1, which is characterized in that the adjusting bracket includes
Linking arm (9), installing arm (10) and mounting base (11), the linking arm (9) and fixed frame (1) hingedly, the installing arm
(10) hingedly with linking arm (9), the linking arm (9) and installing arm (10) are in " 7 " font, and mounting base (11) setting is being pacified
Fill the one end of arm (10) far from linking arm (9).
4. a kind of experimental provision of mouse trachea cannula as claimed in claim 1 or 3, which is characterized in that the fixed frame (1)
There are four upper settings mounting groove (21), and one is formed between four mounting grooves (21) for placing the fixed bit of mouse, four institutes
It states four limbs fixing piece (2) and is provided with flexural pivot (12), hingedly, the four limbs are solid for the flexural pivot (12) and mounting groove (21)
Determining part (2) includes clamping piece (13), and the clamping piece (13) is for clamping mouse four limbs, the clamping piece (13) and flexural pivot
(12) it is movably hinged.
5. a kind of experimental provision of mouse trachea cannula as described in claim 1, which is characterized in that further include having spigot joint
(14), which is used for connecting insertion and ventilator, and the inner tubal wall of the spigot joint (14) is provided with pendulum
(15), the pendulum (15) is flaky, and the edge and intubation inner wall elastic connection, the pendulum (15) of the pendulum (15) can follow
Air-flow is swung, and spigot joint (14) inner wall is provided with foil gauge (16) in pendulum (15) two sides, and the foil gauge (16) is even
Counter (17) are connected to, a closure electricity is formed with counter (17) when foil gauge (16) and pendulum (15) are mutually contradicted and returns
Road, counter (17) start counting, and connect the counter (17) and are connected with relay (18).
6. a kind of experimental provision of mouse trachea cannula as described in claim 1, which is characterized in that be arranged in the elastic string
There are fixing sleeve (19), which is slidably connected with elastic string, which is used to be socketed the tooth of mouse.
7. a kind of experimental provision of mouse trachea cannula as described in claim 1, which is characterized in that clip tongue device (7) set
It is connected to soft glue-line (20).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811313826.8A CN109172030A (en) | 2018-11-06 | 2018-11-06 | A kind of experimental provision of mouse trachea cannula |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811313826.8A CN109172030A (en) | 2018-11-06 | 2018-11-06 | A kind of experimental provision of mouse trachea cannula |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109172030A true CN109172030A (en) | 2019-01-11 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811313826.8A Pending CN109172030A (en) | 2018-11-06 | 2018-11-06 | A kind of experimental provision of mouse trachea cannula |
Country Status (1)
| Country | Link |
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| CN (1) | CN109172030A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111374794A (en) * | 2020-04-22 | 2020-07-07 | 江苏省血吸虫病防治研究所 | Intratracheal injection drug delivery system and method of use |
| CN111514426A (en) * | 2020-06-02 | 2020-08-11 | 华中科技大学同济医学院附属协和医院 | Laboratory rat trachea cannula auxiliary tool and laboratory rat trachea cannula method |
| CN112773990A (en) * | 2019-11-08 | 2021-05-11 | 光武惠文生物科技(北京)有限公司 | Method and apparatus for non-invasive endotracheal intubation of rats or mice |
| CN112998899A (en) * | 2021-02-20 | 2021-06-22 | 中国人民解放军陆军军医大学 | Experimental animal trachea instillator |
| CN115153943A (en) * | 2022-07-11 | 2022-10-11 | 四川大学 | Mouse oral cavity experiment fixing device |
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| CN202654263U (en) * | 2012-06-01 | 2013-01-09 | 浙江大学 | Mouse trachea intubation rack |
| CN205649562U (en) * | 2016-04-15 | 2016-10-19 | 河南医学高等专科学校 | A fixed station for experimental animals trachea cannula |
| CN108042237A (en) * | 2018-01-31 | 2018-05-18 | 付永伟 | Rat oral cavity experimental operation table and its application method |
| CN207734245U (en) * | 2017-05-26 | 2018-08-17 | 遵义医学院 | A kind of mouse surgical fixing plate |
| KR20180114465A (en) * | 2017-04-10 | 2018-10-18 | 경희대학교 산학협력단 | Fixing apparatus for small animals |
| CN108720960A (en) * | 2018-06-14 | 2018-11-02 | 西安交通大学 | A kind of noninvasive fixator for tracheal cannule of animal and method |
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2018
- 2018-11-06 CN CN201811313826.8A patent/CN109172030A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN202654263U (en) * | 2012-06-01 | 2013-01-09 | 浙江大学 | Mouse trachea intubation rack |
| CN205649562U (en) * | 2016-04-15 | 2016-10-19 | 河南医学高等专科学校 | A fixed station for experimental animals trachea cannula |
| KR20180114465A (en) * | 2017-04-10 | 2018-10-18 | 경희대학교 산학협력단 | Fixing apparatus for small animals |
| CN207734245U (en) * | 2017-05-26 | 2018-08-17 | 遵义医学院 | A kind of mouse surgical fixing plate |
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| CN108720960A (en) * | 2018-06-14 | 2018-11-02 | 西安交通大学 | A kind of noninvasive fixator for tracheal cannule of animal and method |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112773990A (en) * | 2019-11-08 | 2021-05-11 | 光武惠文生物科技(北京)有限公司 | Method and apparatus for non-invasive endotracheal intubation of rats or mice |
| CN111374794A (en) * | 2020-04-22 | 2020-07-07 | 江苏省血吸虫病防治研究所 | Intratracheal injection drug delivery system and method of use |
| CN111514426A (en) * | 2020-06-02 | 2020-08-11 | 华中科技大学同济医学院附属协和医院 | Laboratory rat trachea cannula auxiliary tool and laboratory rat trachea cannula method |
| CN112998899A (en) * | 2021-02-20 | 2021-06-22 | 中国人民解放军陆军军医大学 | Experimental animal trachea instillator |
| CN115153943A (en) * | 2022-07-11 | 2022-10-11 | 四川大学 | Mouse oral cavity experiment fixing device |
| CN115153943B (en) * | 2022-07-11 | 2024-07-30 | 四川大学 | Mouse oral experiment fixing device |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190111 |
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| RJ01 | Rejection of invention patent application after publication |