CN112998899A - Experimental animal trachea instillator - Google Patents
Experimental animal trachea instillator Download PDFInfo
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- CN112998899A CN112998899A CN202110192366.3A CN202110192366A CN112998899A CN 112998899 A CN112998899 A CN 112998899A CN 202110192366 A CN202110192366 A CN 202110192366A CN 112998899 A CN112998899 A CN 112998899A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
- A61D7/04—Devices for anaesthetising animals by gases or vapours; Inhaling devices
Abstract
The invention discloses a tracheal instillation device for experimental animals, which comprises an operation table top, wherein the inclination angle of the operation table top is adjustable, an upper incisor fixing mechanism and a lower incisor fixing mechanism are arranged on the operation table top, the tracheal instillation device also comprises a negative pressure tongue pressing mechanism and a tracheal intubation and instillation mechanism, the tracheal intubation and instillation mechanism comprises a hollow tracheal intubation needle, the tail part of the tracheal intubation needle is connected with a tracheal intubation handle, the tail part of the tracheal intubation handle is connected with a tracheal intubation connecting pipe, and the tail end of the tracheal intubation connecting pipe extends into a tracheal intubation indicator; the trachea cannula needle is detachably connected with the trachea cannula handle, and the tail part of the trachea cannula needle can be connected with a liquid injector. The whole device can complete all operations by only one person, and has simpler operation and high success rate, which is superior to the prior device which needs the cooperation of a plurality of persons; meanwhile, the operation is convenient and rapid, the time consumption is short, and the success rate is high.
Description
Technical Field
The invention relates to a tracheal instillation device for an experimental animal.
Background
Respiratory exposure is an important exposure pathway in scientific research fields such as toxicology and clinical medicine. Common respiratory contamination methods are intranasal instillation, exposed tracheal instillation and non-exposed tracheal instillation. Intranasal instillation is simple to operate, but requires drip-injection into the nasal cavity, the operation time is long, and the drip-injection may reach the stomach through the esophagus to cause inaccurate dosage. Exposed tracheal instillation requires general anesthesia of the experimental animals and exposure of the trachea, although with high success rates and accurate instillation, surgical incisions increase trauma and infection risks. The non-exposure type tracheal instillation does not need an operation incision to expose the trachea, and the instillation liquid is conveyed to the lung through the tracheal cannula, so that the contamination dose is accurate, and the injury to experimental animals is small. The non-exposure type tracheal instillation method comprises a plurality of intubation modes such as a transmission light intubation, a blind intubation and an auxiliary intubation using a magnifier, an endoscope and the like, but most of the methods need special equipment, and for small mammals (such as mice or rats), the intubation is difficult due to the anatomical conditions of oral cavities and pharynx parts, the requirement on operation skills is high, and the method needs to be completed by multiple persons in a matching way. Chinese patent CN209827080U discloses a fixing device for non-exposed trachea instillation laboratory mouse, however, the fixing of mouse can only be realized in this patent, and there is also unreliable fixing in the fixing, which can not be applied to mice of various body types, and at least one person is needed to cooperate, and it takes 2 minutes to complete the operation, the efficiency is low, the reliability is low, and the safety is low.
Disclosure of Invention
In order to solve the problems in the prior art, the invention aims to provide a safe, efficient and reliable experimental animal tracheal instillation device capable of carrying out repeated tracheal instillation.
In order to achieve the purpose, the technical scheme of the invention is as follows:
the utility model provides an experimental animals trachea instillation device, includes the operation mesa, the inclination of operation mesa is adjustable, be provided with on the operation mesa and go up incisor fixed establishment, lower incisor fixed establishment, its characterized in that: the upper incisor tooth fixing mechanism comprises an upper incisor tooth fixing nail and an upper incisor tooth pulley which are fixed at the left end and the right end of the operation table board, an upper incisor tooth fixing line is connected at the upper incisor tooth fixing nail, and an upper incisor tooth counter weight is connected after the upper incisor tooth fixing line bypasses the upper incisor tooth pulley; the lower incisor fixing mechanism is positioned at the lower part of the upper incisor fixing mechanism and comprises a lower incisor fixing nail and a lower incisor pulley which are arranged at the left end and the right end of the operation table board, the lower incisor fixing nail is fixedly connected with the operation table board, a slide way which is arranged along the up-down direction is arranged on the operation table board, the lower incisor pulley is arranged in the slide way in a sliding way, a lower incisor fixing line is connected at the lower incisor fixing nail, and the lower incisor fixing line is connected with a lower incisor counterweight after bypassing the lower incisor pulley; the tongue pressing device comprises a tongue pressing mechanism and an air pump, wherein the tongue pressing mechanism comprises a hollow tongue pressing plate, the tail end of the tongue pressing plate is connected with a hollow handle, the tail end of the handle is connected with a negative pressure suction tube, the negative pressure suction tube is connected with a liquid collecting bottle, the air pump is connected with the liquid collecting bottle, and a microswitch for starting the air pump is arranged on the handle; the trachea cannula and drip mechanism comprises a hollow trachea cannula needle, the tail of the trachea cannula needle is connected with a trachea cannula handle, the tail of the trachea cannula handle is connected with a trachea cannula connecting pipe, and the tail end of the trachea cannula connecting pipe extends into a trachea cannula indicator; the trachea cannula needle is detachably connected with the trachea cannula handle, and the tail part of the trachea cannula needle can be connected with a liquid injector.
For the further condition that is applicable to gaseous anesthesia, the top of operation mesa still is provided with anaesthetic mask mechanism, anaesthetic mask mechanism includes anaesthetic mask, anaesthetic mask and anesthesia pipe connection, anaesthetic mask's bottom is less than go up the incisor stationary line.
For further convenient operation, be provided with the recess that is used for anaesthetic mask and pipeline on the operation mesa, the opening on the anaesthetic mask eccentric settings. The eccentric circle is directed to the front side.
For further convenient operation, the middle part of the operation table top is provided with an experimental animal outline groove.
In order to further facilitate the operation, the tongue depressor is provided with a bending part, and the included angle between the front tongue depressor and the rear tongue depressor at the bending part is 20-30 degrees.
For further convenient operation, trachea cannula and instillation mechanism still includes LDE transmission lamp, the LED transmission lamp is installed through adjustable return bend on the operation mesa.
In order to further facilitate the operation, a bend is arranged at a position of 1.2-2.0cm on the front section of the tracheal intubation needle, and an included angle of 15 degrees is formed between the front section and the rear section.
Furthermore, a smooth clip is arranged at a position 0.7-1.2cm away from the tip of the needle head of the tracheal intubation needle, and the diameter of the clip is 2-3mm, and the length of the clip is 4 mm.
Preferably, the endotracheal intubation indicator includes a transparent cylindrical container, and the transparent cylindrical container contains colored indicating liquid. The top end of the transparent cylindrical container is provided with an opening, so that the balance of the air pressure inside and outside the container is ensured.
Furthermore, the bottom edge of the operation table top is provided with a collecting groove for collecting excrement and urine.
Has the advantages that:
the invention provides a trachea instillation device for experimental animals, which can be applied to various experimental animals, such as big and small mice, and can achieve the purpose of fixing the animals by adjusting corresponding counter weights according to the weight difference of the animals, the animals are not damaged, and the operation is simple and convenient. The experimental animal trachea instillation device can be used for small animal trachea instillation operation of gas anesthesia and injection anesthesia, can be used for small animal trachea instillation operation of gas anesthesia when an anesthesia machine mask is installed, and can be used for animal injection anesthesia to operate when the anesthesia machine mask is taken down. The experimental animal trachea instillation device uses the negative pressure suction tongue depressor to clear the oropharynx secretions of the animal, only the microswitch on the handle is needed to be pressed during operation, the clearing is rapid, the effect is good, and the microswitch is needed to be pressed again to clear when the secretions appear again during the operation process, the normal operation is not needed to be stopped, and the operation efficiency is high. When the microswitch is not pressed, the negative pressure suction tongue depressor can be used for picking up the tongue of the animal, and the operation visual field is fully exposed. The trachea cannula part of the experimental animal trachea instillation device consists of a trachea cannula needle, a trachea cannula grip, a trachea cannula connecting pipe and a trachea cannula indicator, and the trachea cannula indicator can objectively reflect whether trachea cannula succeeds or not, so that the success rate of trachea instillation is ensured. The connecting size of the tracheal intubation needle is matched with that of a common injector, after the tracheal intubation is successful, the handle of the tracheal intubation can be pulled out, the injector is connected with the tracheal intubation needle, and the operation of tracheal instillation is completed. According to the experimental animal trachea instillation device, all operations can be completed by only one person, the operation is simpler, the success rate is high, and the experimental animal trachea instillation device is superior to the prior device which needs the cooperation of multiple persons; meanwhile, the operation is convenient and rapid, the time consumption is short, and the success rate is high.
Drawings
FIG. 1 is a schematic view showing the construction of an endotracheal instillation device for experimental animals according to the embodiment (the direction of the arrow is the direction of air flow);
FIG. 2 is a right side view of the work table of embodiment 1;
FIG. 3 is a front view of the table top of example 1 (with upper and lower incisor securing mechanisms);
FIG. 4 is a front view of the work table of example 1 (with an LED transmission lamp);
FIG. 5 is a front view of the operating table of example 1 (with the anaesthetic mask mechanism);
FIG. 6 is a view showing the structure of the injector and the endotracheal intubation needle in example 1.
Detailed Description
The following detailed description of the embodiments of the present invention will be given in conjunction with the accompanying drawings, wherein the following examples are given for the purpose of illustration only and are not to be construed as limiting the scope of the present invention, and other insubstantial modifications and adaptations of the invention will become apparent to those skilled in the art in light of the foregoing disclosure.
Example (b): as shown in fig. 1 to 6, the present embodiment provides a tracheal instillation device for experimental animals, and the tracheal instillation device of the present embodiment can be applied to various experimental animals, such as rats, mice, etc. In this example, a mouse is exemplified.
The tracheal instillation device in the embodiment comprises an operation table top 100, wherein the inclination angle of the operation table top is adjustable. Specifically, the method comprises the following steps: including a base 101 that can arrange the mesa in, set up support frame 102 on the base, set up on the support frame the operation mesa, the back of operation mesa with the support frame support is provided with coupling mechanism 103, coupling mechanism sets up to adjustable form, makes the operation mesa can follow coupling mechanism rotates and then adjusts the angle of operation mesa, wherein, coupling mechanism can be for the face gear or the checkpost mechanism of mutually supporting, and this is prior art, and no longer repeated here.
In addition, the bottom surface of the operation table top can be connected with the front end of the base, and the angle adjustment of the operation table top is realized through the connection structure of the front section of the base and the bottom surface of the operation table top.
In the embodiment, the former arrangement is selected, the size of the operation table is set to be 25 × 50cm, and the bottom edge of the operation table is provided with a collecting groove 104 for collecting excrement and urine. The collecting vat is upwards open-ended U-shaped, and both ends are sealed, will a side of the collecting vat of U-shaped with the connection can be dismantled to operation mesa's base, this will the collecting vat with operation mesa bottom is provided with magnetism and inhales the formula fixed, convenient to detach and clearance.
In addition, be provided with the mechanism that is used for fixed mouse on the operation mesa, including four limbs fixed establishment, upper incisor fixed establishment and lower incisor fixed establishment, wherein, four limbs fixed establishment is unanimous with prior art, and no longer gives details here. The upper incisor fixing mechanism comprises an upper incisor fixing nail 201 and an upper incisor pulley 202 which are fixed at the left end and the right end of the operation table board, an upper incisor fixing line 203 is connected at the upper incisor fixing nail, and an upper incisor counter weight 204 is connected after the upper incisor fixing line winds around the upper incisor pulley; lower incisor tooth fixed establishment is located go up incisor tooth fixed establishment's lower part and including setting up the lower incisor staple 205 and the lower incisor pulley 206 at both ends about the operation mesa, lower incisor staple with operation mesa fixed connection be provided with the slide 207 that sets up along upper and lower direction on the operation mesa, the slide internal slip is established incisor tooth pulley down, incisor staple department is connected with lower incisor tooth fixed line 208 down, lower incisor tooth fixed line walks around be connected with lower incisor tooth counter weight 209 down behind the lower incisor tooth pulley.
In this embodiment, the fixing nails of the upper front tooth fixing mechanism and the fixing nails of the lower front tooth fixing mechanism are respectively arranged at the left side and the right side of the operation table-board, and the upper front tooth pulley and the upper front tooth counter weight of the upper front tooth fixing mechanism and the lower front tooth pulley and the lower front tooth counter weight of the lower front tooth fixing mechanism are respectively arranged at the left side and the right side of the operation table-board.
In this embodiment, the weight may be a metal block or other object with a higher density, and the weight may have multiple specifications for overlapping use. To adapt to mice of different sizes.
In addition, as another embodiment in the present embodiment, a mouse contour groove 105 for housing a mouse is provided in the middle of the operation table. The profile size of the mouse profile groove is set to be larger as much as possible, so that the mouse profile groove can be suitable for mice with different head volumes.
In addition, the tracheal instillation device for the experimental animal in the embodiment further comprises a negative pressure tongue depressing mechanism, wherein the negative pressure tongue depressing mechanism comprises a hollow tongue spatula 301, the tail end of the tongue spatula is connected with a hollow tongue spatula handle 302, the tail end of the tongue spatula handle is connected with a negative pressure suction tube 303, and the negative pressure suction tube is connected with a liquid collecting bottle 304; the negative pressure air pump 305 is further included, the air pump is connected with the liquid collecting bottle, and a microswitch 306 for starting the air pump is arranged on the handle. In this embodiment, the micro switch is located at the rear third of the grip, so that the operator can conveniently hold and operate the micro switch. And the front end of the tongue depressor is an oval opening, so that the tongue depressor can be used as the tongue depressor to jack up the tongue of an animal, and the oropharynx secretions in the deep part of the oral cavity can be sucked out, so that the trachea opening is better exposed. In addition, the tongue depressor is provided with a bending part, the included angle between the front tongue depressor and the rear tongue depressor at the bending part is 20-30 degrees, and the included angle between the front tongue depressor and the rear tongue depressor in the embodiment is 25 degrees.
In addition, the experimental animal trachea instillation device in the embodiment further comprises a trachea cannula and an instillation mechanism, and the trachea cannula and the instillation mechanism in the embodiment can realize the functions of inserting into the trachea and instilling into the trachea. Specifically, the method comprises the following steps: the trachea cannula and instillation mechanism comprises a hollow trachea cannula needle 401, the tail part of the trachea cannula needle is connected with a trachea cannula handle 402, the tail part of the trachea cannula handle is connected with a trachea cannula connecting pipe 403, and the tail end of the trachea cannula connecting pipe extends into a trachea cannula indicator; the trachea cannula needle is detachably connected with the trachea cannula handle, and the tail part of the trachea cannula needle can be connected with a liquid injector. Trachea cannula and drip mechanism still includes LDE transmission lamp 405, LED transmission lamp is installed through adjustable return bend 406 on the operation mesa. The bent pipe can adopt angle-adjustable bent pipes such as a steel screw rod.
Wherein, mouse trachea cannula needle diameter 0.7mm, metal syringe needle length 3.0cm, the front end is smooth, and is provided with the bending in anterior segment 1.2cm department of metal syringe needle, and anterior segment and back end form 15 contained angles. The trachea cannula needle is provided with a smooth clip 407 at a position 0.7cm away from the tip of the needle head, wherein the diameter of the clip is 2mm, and the length of the clip is 4 mm. The endotracheal intubation indicator includes a transparent cylindrical container 404 with an open upper end and a volume of 5ml, and the transparent cylindrical container contains colored indicating liquid, for example, red indicating liquid, and the volume of the indicating liquid is 3 ml. The trachea cannula connecting pipe is inserted into the cylindrical container from the top of the cylindrical container, and the insertion indicating liquid opening of the trachea cannula connecting pipe is 1cm below the liquid level of the indicating liquid. The top end of the transparent cylindrical container is provided with an opening to ensure the balance of the air pressure inside and outside the container.
When the experimental animal is a rat, the diameter of the tracheal intubation needle of the rat is 1.2mm, the length of the metal needle is 6cm, the front end of the metal needle is smooth, a bend is arranged at the 2.0cm position of the front section of the metal needle, and the front section and the rear section form an included angle of 15 degrees. The trachea cannula needle is provided with a smooth clip 407 at a position 1.2cm away from the tip of the needle head, wherein the diameter of the clip is 3mm, and the length of the clip is 4 mm. The other steps were essentially the same as for mice.
After the animals (rats) are anesthetized and fixed on the operating table, the left hand holds the negative pressure tongue depressor to clean oral secretion, gently picks up the tongue and exposes the oropharyngeal portion, so that a small flickering spot can be seen in the deep part of the oropharynx along with the respiration of the animals, the brightening spot is the opening of a trachea, the tracheal intubation needle is connected with the tracheal intubation handle, the right hand holds the tracheal intubation handle, the bent concave surface of the tracheal intubation needle faces the ventral side of the animals, when the flickering of the opening of the trachea is seen, the tracheal intubation needle is inserted from the brightening spot, the clip at the front end of the tracheal intubation needle is just clamped at the opening of the trachea of the small animals, whether the liquid level of the tracheal intubation connecting pipe in the tracheal intubation indicator fluctuates up and down along with the respiration of the small animals is immediately observed, the fluctuation can determine that the tracheal intubation needle is correctly inserted into the trachea of the animals, and the tracheal intubation needle can be stabilized by the left hand, then, the endotracheal tube grip is pulled out, the syringe 408 is used to suck the required liquid, and the syringe and the endotracheal tube needle are connected, so that the operation of endotracheal instillation can be performed.
As another implementation manner in this embodiment, an anesthetic mask mechanism is further disposed on the top of the operation table, and the anesthetic mask mechanism includes an anesthetic mask 501, and the anesthetic mask is connected to an anesthetic line 502. And the bottom end of the anaesthetic mask is lower than the upper incisor fixing line, specifically, the bottom end of the anaesthetic mask is lower than the upper incisor fixing line by 0.5 cm. The operating table top is provided with a groove 105 for an anesthesia mask and a pipeline, and a depression 106 is also arranged at the contact position of the anesthesia machine pipeline and the operating table, so that the pipeline does not protrude too much, and the sight of an operator is not obstructed. The opening 503 of the anaesthetic mask is made of soft rubber, and the center of the opening is eccentrically arranged. The part of the mask which is not opened is embedded in the operating platform, the opening of the anaesthetic mask is flush with the operating platform, the front end of the head and the nose of a mouse can be clamped in the anaesthetic mask, and the air tightness of the anaesthetic mask combined with an animal and the fact that the mask does not protrude out of the platform surface to cause the sight obstruction are ensured.
The device of this embodiment both can be used for gas anesthesia and also can be used for injecting the animal of anesthesia and carry out the trachea instillation operation, and fixed anesthesia machine face guard operates when carrying out gas anesthesia, and it can to take off anesthesia face guard mechanism when the mouse adopts the injection anesthesia. Can change the anaesthetic mask with different specifications openings according to the size of the mouse body.
As another implementation of this embodiment, still hang on the operation mesa and be equipped with tweezers and tongue clamp, tweezers and tongue clamp front end all can twine soft cloth, can guarantee not to harm the animal, when using gaseous anesthesia, accomplish to transfer the animal to the operation panel after induced anesthesia fast, fill in the anaesthetic mask with the nose of animal, fix the last front tooth with last front tooth fixed line, then fix the lower front tooth with lower front tooth fixed line, then fix four limbs, after fixing well pull out the tongue of animal gently with tweezers, clip the tongue gently with the tongue clamp, make the tongue of animal draw to one side. The upper incisor fixing line and the lower incisor fixing line are smooth flexible wires, so that the upper incisor fixing line just clamps the nose of the animal in the anaesthetic mask, and the lower incisor fixing line exposes the oral cavity of the animal, so that the animal cannot be damaged.
In addition, a power supply is also arranged and supplies power to the LED transmission lamp and the microswitch. A power switch may be provided on the base.
In addition, the present embodiment provides an operation method based on the above experimental animal tracheal instillation device:
step one, a regulating device: the weight of the upper front tooth counter weight and the weight of the lower front tooth counter weight are adjusted according to the size of the animal, and the distance between the lower front tooth fixing line and the upper front tooth fixing line is adjusted through the sliding rail. If the animal is anesthetized by gas, the mask of the anesthesia machine is required to be fixed on the operating platform, and if the animal is anesthetized by injection, the mask of the anesthesia machine is not required to be installed; turning on power supplies of the LED transmission lamp and the negative-pressure tongue depressor;
secondly, fixing the mice: after the rats are anesthetized, the animals are quickly transferred to an operation table, the nose parts of the animals are plugged into an anesthetic mask, upper incisors are fixed by upper incisor fixing lines, lower incisors are fixed by lower incisor fixing lines, four limbs are fixed, after the animals are fixed, the tongues of the animals are slightly pulled out by tweezers, and the tongues are slightly clamped by tongue clamps to enable the tongues of the animals to be pulled to one side; adjusting the bent tube of the LED lamp to enable the light to be vertically incident from the neck of the animal; (gas anesthesia is divided into induction anesthesia and maintenance anesthesia, the induction anesthesia is completed in an induction box, the maintenance anesthesia provides anesthesia gas for an anesthesia machine mask on an operation table, the injection anesthesia is generally intraperitoneal injection, and the injection is only needed after the injection);
thirdly, clearing oropharynx secretions and exposing visual field: an operator is positioned at the rear side of the device, holds the negative-pressure tongue depressor by the left hand, the forefinger is arranged on the microswitch, the tongue depressor is stretched into the oral cavity of an animal, the tongue of the animal is lifted forwards, the oropharynx part is exposed, the forefinger presses the microswitch, the air pump starts to work, negative pressure is generated in the negative-pressure suction tube, the tongue depressor sucks the oropharynx secretions to the negative-pressure liquid collecting bottle through the negative-pressure suction tube, a twinkling small bright spot can be seen in the deep part of the oropharynx along with the breathing of the animal, the bright spot is the opening of the trachea, and the cleaning;
step four, trachea intubation and instillation: holding the negative-pressure tongue depressor by the left hand to maintain the previous operation, keeping the exposure of the opening of the trachea, connecting the tracheal cannula needle with the tracheal cannula handle, holding the tracheal cannula handle by the right hand, enabling the curved concave surface of the tracheal cannula needle to face the ventral side of the animal, inserting the tracheal cannula needle from a bright spot when the opening of the trachea is observed to flicker, enabling a clamp at the front end of the tracheal cannula needle to be just clamped at the opening of the trachea of the small animal, observing whether the liquid level of the tracheal cannula connecting pipe in the tracheal cannula indicator fluctuates up and down along with the respiration of the small animal or not, determining that the tracheal cannula needle is correctly inserted into the trachea of the animal by fluctuation, stabilizing the tracheal cannula needle by the left hand at the moment, pulling out the tracheal cannula handle, sucking required liquid by an injector, connecting the injector with the tracheal cannula needle, instilling the liquid in the trachea of the mouse, and finishing the operation of instilling, after instillation, the rat keeps the current body position for a plurality of seconds, gently massages the chest of the rat, and observes whether asphyxia exists or not;
and fifthly, after the instillation is finished, the tracheal intubation needle is pulled out, the tongue clamp is taken down, the upper and lower incisors and the four limbs are unfastened, and the mouse is placed on a constant temperature plate to wait for revival. The opening of the air outlet end of the air pump is matched with the tracheal intubation needle, so that the air pump can be used for cleaning the tracheal intubation needle and avoiding blockage.
The experimental animal tracheal instillation device and method of the embodiment are adopted: can fix big and small mice, can adjust the corresponding counter weight according to the difference of animal weight, can reach the purpose of fixed animal, do not harm the animal, easy operation is convenient. The experimental animal trachea instillation device can be used for small animal trachea instillation operation of gas anesthesia and injection anesthesia, can be used for small animal trachea instillation operation of gas anesthesia when an anesthesia machine mask is installed, and can be used for animal injection anesthesia to operate when the anesthesia machine mask is taken down. The experimental animal trachea instillation device uses the negative pressure suction tongue depressor to clear the oropharynx secretions of the animal, only the microswitch on the handle is needed to be pressed during operation, the clearing is rapid, the effect is good, and the microswitch is needed to be pressed again to clear when the secretions appear again during the operation process, the normal operation is not needed to be stopped, and the operation efficiency is high. When the microswitch is not pressed, the negative pressure suction tongue depressor can be used for picking up the tongue of the animal, and the operation visual field is fully exposed. The trachea cannula part of the experimental animal trachea instillation device of the embodiment consists of a trachea cannula needle, a trachea cannula grip, a trachea cannula connecting pipe and a trachea cannula indicator, and the trachea cannula indicator can objectively reflect whether trachea cannula succeeds or not, so that the success rate of trachea instillation is ensured. The connecting size of the tracheal intubation needle is matched with that of a common injector, after the tracheal intubation is successful, the handle of the tracheal intubation can be pulled out, the injector is connected with the tracheal intubation needle, and the operation of tracheal instillation is completed. According to the experimental animal trachea instillation device, all operations can be completed by only one person, the operation is simpler, the success rate is high, and the experimental animal trachea instillation device is superior to the prior device which needs the cooperation of multiple persons; meanwhile, the operation is convenient and rapid, the time consumption is short, and the success rate is high.
Claims (10)
1. The utility model provides an experimental animals trachea instillation device, includes the operation mesa, the inclination of operation mesa is adjustable, be provided with on the operation mesa and go up incisor fixed establishment, lower incisor fixed establishment, its characterized in that:
the upper incisor tooth fixing mechanism comprises an upper incisor tooth fixing nail and an upper incisor tooth pulley which are fixed at the left end and the right end of the operation table board, an upper incisor tooth fixing line is connected at the upper incisor tooth fixing nail, and an upper incisor tooth counter weight is connected after the upper incisor tooth fixing line bypasses the upper incisor tooth pulley;
the lower incisor fixing mechanism is positioned at the lower part of the upper incisor fixing mechanism and comprises a lower incisor fixing nail and a lower incisor pulley which are arranged at the left end and the right end of the operation table board, the lower incisor fixing nail is fixedly connected with the operation table board, a slide way which is arranged along the up-down direction is arranged on the operation table board, the lower incisor pulley is arranged in the slide way in a sliding way, a lower incisor fixing line is connected at the lower incisor fixing nail, and the lower incisor fixing line is connected with a lower incisor counterweight after bypassing the lower incisor pulley;
the negative pressure tongue pressing mechanism comprises a hollow tongue pressing plate, a hollow handle is connected to the tail end of the tongue pressing plate, a negative pressure suction tube is connected to the tail end of the handle, a liquid collecting bottle is connected to the negative pressure suction tube, the negative pressure suction tube further comprises an air pump, the air pump is connected with the liquid collecting bottle, and a microswitch for starting the air pump is arranged on the handle;
the trachea cannula and drip mechanism comprises a hollow trachea cannula needle, the tail of the trachea cannula needle is connected with a trachea cannula handle, the tail of the trachea cannula handle is connected with a trachea cannula connecting pipe, and the tail end of the trachea cannula connecting pipe extends into a trachea cannula indicator;
the trachea cannula needle is detachably connected with the trachea cannula handle, and the tail part of the trachea cannula needle can be connected with a liquid injector.
2. The experimental animal tracheal instillation device of claim 1, wherein: the top of operation mesa still is provided with anaesthetic mask mechanism, anaesthetic mask mechanism includes anaesthetic mask, anaesthetic mask and anesthesia pipe connection, anaesthetic mask's bottom is less than go up incisor fixed line.
3. The experimental animal tracheal instillation device of claim 2, wherein: the operation table top is provided with a groove for an anaesthetic mask and a pipeline, and an opening on the anaesthetic mask is eccentrically arranged.
4. A laboratory animal tracheal instillation device according to claim 1, 2 or 3, wherein: an animal outline groove is arranged in the middle of the operation table top.
5. The experimental animal tracheal instillation device of claim 4, wherein: the tongue depressor is provided with a bending part, and the included angle between the front tongue depressor and the rear tongue depressor at the bending part is 20-30 degrees.
6. The experimental animal tracheal instillation device of claim 5, wherein: trachea cannula and instillation mechanism still includes LDE transmission lamp, LED transmission lamp passes through adjustable return bend and installs on the operation mesa.
7. The experimental animal tracheal instillation device of claim 6, wherein: a bend is arranged at a position 1.2-2.0cm away from the front section of the tracheal intubation needle, and an included angle of 15 degrees is formed between the front section and the rear section.
8. The experimental animal tracheal instillation device of claim 7, wherein: the trachea cannula needle is provided with a smooth clip at a position 0.7-1.2cm away from the tip of the needle head, and the clip has the diameter of 2-3mm and the length of 4 mm.
9. The experimental animal tracheal instillation device of claim 8, wherein: the trachea cannula indicator comprises a transparent cylindrical container, wherein colored indicating liquid is contained in the transparent cylindrical container, and an opening is formed in the top end of the transparent cylindrical container.
10. The experimental animal tracheal instillation device of claim 9, wherein: the bottom edge of the operation table top is provided with a collecting groove for collecting excrement and urine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110192366.3A CN112998899B (en) | 2021-02-20 | 2021-02-20 | Experimental animal trachea instillator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110192366.3A CN112998899B (en) | 2021-02-20 | 2021-02-20 | Experimental animal trachea instillator |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112998899A true CN112998899A (en) | 2021-06-22 |
| CN112998899B CN112998899B (en) | 2022-09-02 |
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