CN108478305A - For the three-dimensional fixed adapter of mouse brain - Google Patents
For the three-dimensional fixed adapter of mouse brain Download PDFInfo
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- CN108478305A CN108478305A CN201810370997.8A CN201810370997A CN108478305A CN 108478305 A CN108478305 A CN 108478305A CN 201810370997 A CN201810370997 A CN 201810370997A CN 108478305 A CN108478305 A CN 108478305A
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- 210000004556 brain Anatomy 0.000 title claims abstract description 23
- 230000007246 mechanism Effects 0.000 claims abstract description 26
- 210000004283 incisor Anatomy 0.000 claims description 6
- 230000006835 compression Effects 0.000 claims description 4
- 238000007906 compression Methods 0.000 claims description 4
- 239000002184 metal Substances 0.000 claims description 4
- 230000001105 regulatory effect Effects 0.000 abstract 3
- 241000699666 Mus <mouse, genus> Species 0.000 description 34
- 210000003128 head Anatomy 0.000 description 22
- 241001465754 Metazoa Species 0.000 description 16
- 230000000007 visual effect Effects 0.000 description 12
- 241000700159 Rattus Species 0.000 description 9
- 230000000694 effects Effects 0.000 description 6
- 241000282693 Cercopithecidae Species 0.000 description 3
- 241000282326 Felis catus Species 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 210000000214 mouth Anatomy 0.000 description 3
- 210000002569 neuron Anatomy 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 2
- 230000001815 facial effect Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000010365 information processing Effects 0.000 description 1
- 230000009456 molecular mechanism Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
- A61D2003/003—Appliances for supporting or fettering animals for operative purposes with head or neck restraining means
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Husbandry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Instructional Devices (AREA)
- Position Input By Displaying (AREA)
Abstract
The invention discloses one kind for the three-dimensional fixed adapter of mouse brain, and workbench is provided with First terrace and second step face from top to bottom；Its width direction of First terrace upper edge is provided with two columns, the homonymy of two columns is located at mutually level position and is connected with limit base, the through-hole that axis direction is parallel to First terrace width direction is provided on limit base, slidably adjustably inserted with ear bar in each through-hole, the one end of two ear bars to each other is set as tip；Regulating mechanism can be connected with front tooth bar in the length direction slidable adjustment in second step face, regulating mechanism, and front tooth bar includes level board and vertical bar；Vertical bar is set on regulating mechanism and vertically can be fixed in the top of vertical bar in slidable adjustment, one end of level board, and the other end is provided with incisive foramen and extends towards the gap direction between two columns.The adapter by the head of mouse for fixing and carrying out biological study experiment.
Description
Technical Field
The invention relates to an animal experiment device, in particular to an adapter for three-dimensional fixation of mouse brain.
Background
The research on the discharge activity of nerve cells of the rat and the mouse visual system and the combination of the research on cell and molecular biology have important theoretical value for further discussing the visual information processing and the cell molecular mechanism of visual plasticity, but the animal head fixing mode of the existing rat brain stereotaxic instrument blocks most of the visual field of the animal, and is not suitable for the research on the induced electrical activity of the cells of the visual system.
Currently, there are two main categories of brain stereotaxic instruments available on the market: 1) the brain stereotaxic instrument for large animals (monkey, cat, etc.) is mainly used for electrophysiological recording of the monkey, cat, etc. Because the facial organs of the monkey/cat are distributed in a space almost in a vertical position, the vertical distance between the eyes and the oral cavity is larger, the head is fixed by adopting three parts, namely an ear rod (earbar), a mouth rod (bite bar) and an eye rod (eye bar), and the visual field of the animal is not blocked. However, the facial organs of the rats and mice are distributed in a slightly horizontal position in space, the vertical distance between the eyes and the oral cavity is small, the heads of the rats and the mice cannot be firmly fixed by the brain stereotaxic apparatus, and the visual field of the animals can be blocked. 2) The brain stereotaxic instrument for small animals (rats/mice) adopts two parts of ear rods and incisors for fixing, which can firmly fix the head of the animal, but because the incisors fixing device is positioned right in front of the animal and is positioned on the same plane with the head of the animal, most of the visual field of the animal is blocked, and the visual stimulation cannot be normally presented to the animal, so the instrument is not suitable for the visual electrophysiological recording experiment.
Disclosure of Invention
The invention aims to provide an adapter for three-dimensional fixation of a mouse brain, which fixes the head of a mouse, is convenient for researching the electrical activity of nerve cells related to mouse vision, can also research the electrical activity of neurons in other brain areas, has no influence on the sight of the mouse and has high success rate of experiments.
In order to achieve the purpose, the invention provides an adapter for three-dimensional fixation of a mouse brain, which comprises a step-shaped workbench, wherein a first step surface and a second step surface are arranged on the workbench from top to bottom; the first step surface is provided with two upright posts along the width direction, a gap for placing the head of a mouse is formed between the two upright posts, the positions at the same height on the same sides of the two upright posts are fixedly connected with a limiting seat, the limiting seat is provided with through holes with the axial direction parallel to the width direction of the first step surface, each through hole is internally inserted with an ear rod in a sliding and adjusting manner, and one end of each of the two ear rods facing each other is set to be a tip; an adjusting mechanism is arranged on the second step surface and can be adjusted in a sliding mode along the length direction of the second step surface, a door tooth rod is connected to the adjusting mechanism, and the door tooth rod comprises a horizontal plate and a vertical rod; the vertical rod is arranged on the adjusting mechanism and can be adjusted in a sliding mode in the vertical direction, one end of the horizontal plate is fixedly connected to the top end of the vertical rod, and the other end of the horizontal plate is provided with a door tooth hole and extends towards the direction of a gap between the two stand columns.
Preferably, the upper surface of horizontal plate is provided with the fixed block, the fixed block is close to the one end rigid coupling of door tooth hole has the wire, the wire is kept away from the one end of fixed block sets up to be used for pressing the arc hook of mouse upper jaw and nasal part.
Preferably, the curved hook is bent horizontally toward any one of the columns.
Preferably, the fixing block is provided with a mounting hole, and a bolt passes through the mounting hole and is screwed on the horizontal plate to fix the fixing block.
Preferably, a compression spring is sleeved on the bolt between the fixed block and the horizontal plate.
Preferably, the side wall of the limiting seat is provided with a first threaded through hole, and a first screw matched with the first threaded through hole spirally extends into the through hole through the first threaded through hole to compress the ear rod.
Preferably, the two ends of the ear rods, which face away from each other, are provided with handles.
Preferably, the handle is circular, polygonal, oval or a rod body perpendicular to the ear rod.
Preferably, the adjustment mechanism comprises: the vertical plate is fixedly connected to the horizontal sliding plate; a threaded hole is formed in the second step surface, a strip-shaped hole which is matched with the threaded hole and is parallel to the length direction of the second step surface is formed in the horizontal sliding plate, and a second screw penetrates through the strip-shaped hole and is in threaded connection with the threaded hole so as to adjust the position of the horizontal sliding plate and fix the horizontal sliding plate; the vertical plate is provided with a vertical sliding groove or a vertical sliding hole, the vertical rod is vertically inserted into the sliding groove or the vertical sliding hole and can slide along the vertical direction, the side wall of the sliding groove or the vertical sliding hole is provided with at least one second threaded through hole, and a third screw matched with the second threaded through hole spirally extends into the sliding groove or the vertical sliding hole through the second threaded through hole to extrude and fix the vertical plate.
Preferably, the distance between the first step surface and the second step surface is 5-10 cm.
According to the technical scheme, the adapter comprises a step-shaped workbench, wherein a first step surface and a second step surface are arranged on the workbench from top to bottom; the first step surface is provided with two upright posts along the width direction, a gap for placing the head of a mouse is formed between the two upright posts, the positions at the same height on the same sides of the two upright posts are fixedly connected with a limiting seat, the limiting seat is provided with through holes with the axial direction parallel to the width direction of the first step surface, each through hole is internally inserted with an ear rod in a sliding and adjusting manner, and one end of each of the two ear rods facing each other is set to be a tip; an adjusting mechanism is arranged on the second step surface and can be adjusted in a sliding mode along the length direction of the second step surface, a door tooth rod is connected to the adjusting mechanism, and the door tooth rod comprises a horizontal plate and a vertical rod; the vertical rod is arranged on the adjusting mechanism and can be adjusted in a sliding mode in the vertical direction, one end of the horizontal plate is fixedly connected to the top end of the vertical rod, and the other end of the horizontal plate is provided with a door tooth hole and extends towards the direction of a gap between the two stand columns. During the experiment, place the mouse on first step face, the sight of mouse is towards the direction of second step face, touch the fixed point on the temporalis bone with the most advanced of two ear poles through the ear hole of animal, adjust the left and right sides position of two side ear poles, make the head of animal be located the central position of two side ear poles, it is fixed around realizing the mouse head, the door tooth that the door tooth hole cover mouse on the water flat board realizes fixing for about the upper and lower of mouse head, thereby accomplish the fixed of mouse head, so as to get into the experiment on next step, because the height of first step face is higher than the height of second step face, when carrying out the visual experiment to the mouse, can not blockked with the part above it by adjustment mechanism, improve the success rate of experiment.
Additional features and advantages of the invention will be set forth in the detailed description which follows.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:
fig. 1 is a schematic view of the overall structure of a preferred embodiment of the adapter of the present invention.
Description of the reference numerals
1 first step surface 2 second step surface
3 upright post 4 spacing seat
5 ear rod 6 first screw
7 handle 8 vertical rod
9 bolt 10 fixed block
11 arc hook 12 door tooth hole
13 horizontal plate 14 horizontal sliding plate
15 bar-shaped hole 16 vertical plate
17 second screw 18 third screw
Detailed Description
The following detailed description of embodiments of the invention refers to the accompanying drawings. It should be understood that the detailed description and specific examples, while indicating the present invention, are given by way of illustration and explanation only, not limitation.
In the present invention, unless otherwise specified, directional words included in terms such as "upper, lower, left, right, front, rear, inner, and outer" and the like merely represent the directions of the terms in a normal use state or are colloquially known by those skilled in the art, and should not be construed as limiting the terms. It should be noted that, in the application document, the length direction of the first step surface 1 and the second step surface 2 refers to the horizontal extension direction of the step of the stepped workbench, and the width direction of the first step surface 1 and the second step surface 2 refers to the extension direction of each step facing to the two ends of the step.
Referring to the adapter for stereo fixation of the mouse brain shown in fig. 1, the adapter comprises a step-shaped workbench, wherein a first step surface 1 and a second step surface 2 are arranged on the workbench from top to bottom; two upright posts 3 are arranged on the first step surface 1 along the width direction of the first step surface, a gap for placing mouse heads is formed between the two upright posts 3, the positions, which are positioned at the same height, on the same sides of the two upright posts 3 are fixedly connected with a limiting seat 4, through holes are arranged on the limiting seat 4, the axis direction of each through hole is parallel to the width direction of the first step surface, an ear rod 5 is inserted into each through hole in a sliding and adjusting manner, and one end of each of the two ear rods 5 facing each other is arranged to be a tip end; the second step surface 2 is provided with an adjusting mechanism, the adjusting mechanism can be adjusted in a sliding mode along the length direction of the second step surface 2, the adjusting mechanism is connected with a door tooth rod, and the door tooth rod comprises a horizontal plate 13 and a vertical rod 8; the vertical rod 8 is arranged on the adjusting mechanism and can be adjusted in a sliding mode along the vertical direction, one end of the horizontal plate 13 is fixedly connected to the top end of the vertical rod 8, and the other end of the horizontal plate is provided with a door tooth hole 12 and extends towards the direction of the gap between the two upright posts 3.
Through the implementation of the technical scheme, the adapter comprises a step-shaped workbench, wherein a first step surface 1 and a second step surface 2 are arranged on the workbench from top to bottom; two upright posts 3 are arranged on the first step surface 1 along the width direction of the first step surface, a gap for placing mouse heads is formed between the two upright posts 3, the positions, which are positioned at the same height, on the same sides of the two upright posts 3 are fixedly connected with a limiting seat 4, through holes are arranged on the limiting seat 4, the axis direction of each through hole is parallel to the width direction of the first step surface, an ear rod 5 is inserted into each through hole in a sliding and adjusting manner, and one end of each of the two ear rods 5 facing each other is arranged to be a tip end; the second step surface 2 is provided with an adjusting mechanism, the adjusting mechanism can be adjusted in a sliding mode along the length direction of the second step surface 2, the adjusting mechanism is connected with a door tooth rod, and the door tooth rod comprises a horizontal plate 13 and a vertical rod 8; the vertical rod 8 is arranged on the adjusting mechanism and can be adjusted in a sliding mode along the vertical direction, one end of the horizontal plate 13 is fixedly connected to the top end of the vertical rod 8, and the other end of the horizontal plate is provided with a door tooth hole 12 and extends towards the direction of the gap between the two upright posts 3. During the experiment, place the mouse on first step face 1, the sight of mouse is towards the direction of second step face 2, the most advanced of two ear stems 5 touches the fixed point on the temporale bone through the ear hole of animal, the position about two side ear stems 5 has been adjusted, make the head of animal be located the central position of two side ear stems 5, it is fixed around realizing the mouse head, the door tooth that rethread door tooth hole 12 on the water flat 13 entangles the mouse realizes fixing for about the top and bottom of mouse head, thereby accomplish the fixing of mouse head, so as to get into the experiment on next step, because the height of first step face 1 is higher than the height of second step face 2, when carrying out the visual experiment to the mouse, can not be blockked with the part above it by adjustment mechanism, improve the success rate of experiment.
In this embodiment, in order to further fix the head of the rat, it is preferable that a fixing block 10 is disposed on the upper surface of the horizontal plate 13, a wire is fixedly connected to an end of the fixing block 10 close to the incisor holes 12, and an arc-shaped hook 11 for pressing the upper jaw and the nose of the rat is disposed at an end of the wire far from the fixing block 10. The part between the upper jaw and the nose of the mouse is pressed by the arc-shaped hook 11. The incisors of the mouse are firmly fixed in the incisor holes 12. Thus, the head of the mouse cannot move in the front, rear, up and down positions.
In this embodiment, in order to further make the curved hook 11 match the part between the upper jaw and the nose of the mouse, and obtain a better pressing effect, it is preferable that the curved hook 11 is horizontally bent toward any one of the pillars 3.
In this embodiment, in order to achieve the detachability of the fixing block 10, it is preferable that the fixing block 10 is provided with a mounting hole through which a bolt 9 passes and is screwed to the horizontal plate 13 to fix the fixing block 10.
In this embodiment, in order to be suitable for experiments on rats of different sizes, it is preferable that a compression spring is sleeved on the bolt 9 between the fixing block 10 and the horizontal plate 13. Vertical distance between the arc-shaped hook 11 and the door tooth hole 12 can be adjusted through the arrangement of the compression spring, so that the heads of rats with different sizes can be fixed.
In this embodiment, in order to further fix the position of the ear rod 5, it is preferable that a first threaded through hole is provided on the side wall of the limiting seat 4, and a first screw 6 matched with the first threaded through hole extends into the through hole in a spiral manner through the first threaded through hole to press the ear rod 5.
In this embodiment, in order to facilitate the adjustment of the position of the ear stems 5, it is preferable that the ends of the two ear stems 5 facing away from each other are provided with handles 7. The shape of the handle 7 can be chosen within wide limits, preferably the handle 7 is circular, polygonal, oval or a rod perpendicular to the ear stem 5.
In this embodiment, in order to achieve the front, rear, up and down adjustment of the horizontal plate 13 and the wire, it is preferable that the adjusting mechanism includes: the vertical plate 16 is fixedly connected to the horizontal sliding plate 14; a threaded hole is formed in the second step surface 2, a strip-shaped hole 15 which is matched with the threaded hole and is parallel to the length direction of the second step surface 2 is formed in the horizontal sliding plate 14, and a second screw 17 penetrates through the strip-shaped hole 15 and is in threaded connection with the threaded hole so as to adjust the position of the horizontal sliding plate 14 and fix the horizontal sliding plate; the vertical plate 16 is provided with a vertical sliding groove or a vertical sliding hole, the vertical rod 8 is vertically inserted into the sliding groove or the vertical sliding hole and can slide along the vertical direction, the side wall of the sliding groove or the vertical sliding hole is provided with at least one second threaded through hole, and a third screw 18 matched with the second threaded through hole spirally extends into the sliding groove or the vertical sliding hole through the second threaded through hole to extrude and fix the vertical plate 16. The second screws 17 are fixed at different positions of the strip-shaped hole 15 by sliding the horizontal sliding plate 14 front and back to adjust the horizontal distance between the horizontal plate 13 and the metal wire from the head of the mouse; the vertical rod 8 slides in the sliding groove or the sliding hole and compresses the vertical rod 8 to fix the height position through the third screw 18 and the second threaded hole, so that the vertical positions of the horizontal plate 13 and the metal wire can be adjusted, and the experimental range of different mouse body types can be enlarged.
In this embodiment, in order to obtain a better experimental effect, it is preferable that the distance between the first step surface 1 and the second step surface 2 is 5 to 10 cm.
The preferred embodiments of the present invention have been described in detail with reference to the accompanying drawings, however, the present invention is not limited to the specific details of the above embodiments, and various simple modifications can be made to the technical solution of the present invention within the technical idea of the present invention, and these simple modifications are within the protective scope of the present invention.
It should be noted that the various technical features described in the above embodiments can be combined in any suitable manner without contradiction, and the invention is not described in any way for the possible combinations in order to avoid unnecessary repetition.
In addition, any combination of the various embodiments of the present invention is also possible, and the same should be considered as the disclosure of the present invention as long as it does not depart from the spirit of the present invention.
Claims (10)
1. An adapter for three-dimensional fixation of mouse brain is characterized in that the adapter comprises a step-shaped workbench, and a first step surface (1) and a second step surface (2) are arranged on the workbench from top to bottom;
the first step surface (1) is provided with two upright posts (3) along the width direction, a gap for placing the head of a mouse is formed between the two upright posts (3), the same sides of the two upright posts (3) at the same height are fixedly connected with a limiting seat (4), the limiting seat (4) is provided with through holes of which the axial direction is parallel to the width direction of the first step surface (1), each through hole is internally inserted with an ear rod (5) in a sliding and adjusting manner, and one end of each of the two ear rods (5) facing each other is arranged to be a tip end;
an adjusting mechanism is arranged on the second step surface (2), the adjusting mechanism can be adjusted in a sliding mode along the length direction of the second step surface (2), a door tooth rod is connected to the adjusting mechanism, and the door tooth rod comprises a horizontal plate (13) and a vertical rod (8); wherein,
the vertical rod (8) is arranged on the adjusting mechanism and can be adjusted in a sliding mode in the vertical direction, one end of the horizontal plate (13) is fixedly connected to the top end of the vertical rod (8), the other end of the horizontal plate is provided with a door tooth hole (12) and extends towards the two gap directions between the stand columns (3).
2. The adapter for stereo mouse brain fixation according to claim 1, wherein a fixing block (10) is arranged on the upper surface of the horizontal plate (13), a metal wire is fixedly connected to one end, close to the incisor hole (12), of the fixing block (10), and an arc-shaped hook (11) for pressing the upper jaw and the nose of a mouse is arranged at one end, far away from the fixing block (10), of the metal wire.
3. The adapter for stereotactic mouse brain according to claim 2, wherein said curved hook (11) is bent horizontally toward any one of said columns (3).
4. The adapter for stereotactic mouse brain according to claim 2, wherein said fixation block (10) is provided with a mounting hole through which a bolt (9) passes and is screwed on said horizontal plate (13) to fix said fixation block (10).
5. The adapter for the stereotactic fixation of the mouse brain according to claim 4, wherein a compression spring is sleeved on the bolt (9) between the fixed block (10) and the horizontal plate (13).
6. The adapter for stereo fixation of the mouse brain according to claim 1, wherein a first threaded through hole is formed in a side wall of the limiting seat (4), and a first screw (6) matched with the first threaded through hole extends into the through hole in a spiral mode through the first threaded through hole so as to press the ear rod (5).
7. Adapter for spatial rat brain fixation according to claim 1, wherein the two ear rods (5) are provided with a handle (7) at the end facing away from each other.
8. The adapter for stereo fixation of the mouse brain according to claim 7, wherein the handle (7) is circular, polygonal, oval or a rod body perpendicular to the ear rod (5).
9. The adapter for stereotactic fixation of a mouse brain according to any of claims 1-8, wherein said adjustment mechanism comprises: the device comprises a vertical plate (16) and a horizontal sliding plate (14), wherein the vertical plate (16) is fixedly connected to the horizontal sliding plate (14);
a threaded hole is formed in the second step surface (2), a strip-shaped hole (15) which is matched with the threaded hole and is parallel to the length direction of the second step surface (2) is formed in the horizontal sliding plate (14), and a second screw (17) penetrates through the strip-shaped hole (15) and is screwed in the threaded hole so as to adjust the position of the horizontal sliding plate (14) and fix the horizontal sliding plate;
the vertical plate (16) is provided with a vertical sliding groove or a vertical sliding hole, the vertical rod (8) is vertically inserted into the sliding groove or the vertical sliding hole and can slide along the vertical direction, the side wall of the sliding groove or the vertical sliding hole is provided with at least one second threaded through hole, and a third screw (18) matched with the second threaded through hole spirally extends into the sliding groove or the vertical sliding hole through the second threaded through hole to extrude and fix the vertical plate (16).
10. The adapter for stereotactic mouse brain fixation according to claim 1, wherein the distance between said first step surface (1) and said second step surface (2) is 5-10 cm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810370997.8A CN108478305B (en) | 2018-04-24 | 2018-04-24 | Adapter for three-dimensional fixation of mouse brain |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810370997.8A CN108478305B (en) | 2018-04-24 | 2018-04-24 | Adapter for three-dimensional fixation of mouse brain |
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| CN108478305A true CN108478305A (en) | 2018-09-04 |
| CN108478305B CN108478305B (en) | 2024-04-19 |
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| CN201810370997.8A Active CN108478305B (en) | 2018-04-24 | 2018-04-24 | Adapter for three-dimensional fixation of mouse brain |
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| CN111134889A (en) * | 2020-01-10 | 2020-05-12 | 浙江大学 | A mouse fixing device for ophthalmology high resolution detects experiment |
| CN111227988A (en) * | 2020-03-17 | 2020-06-05 | 中国科学院深圳先进技术研究院 | Brain stereotactic injection device |
| CN111888036A (en) * | 2020-07-31 | 2020-11-06 | 福建医科大学附属第一医院 | Fixing structure of rat brain stereotaxic instrument |
| CN113141766A (en) * | 2021-04-16 | 2021-07-20 | 中国科学院深圳先进技术研究院 | Electrophysiological experiment shielding box |
| CN113598801A (en) * | 2021-08-12 | 2021-11-05 | 徐州医科大学 | Head fixing device for PET-CT scanning anesthesia rat of small animal |
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|---|---|---|---|---|
| CN111134889A (en) * | 2020-01-10 | 2020-05-12 | 浙江大学 | A mouse fixing device for ophthalmology high resolution detects experiment |
| CN111134889B (en) * | 2020-01-10 | 2021-03-05 | 浙江大学 | A mouse fixing device for ophthalmology high resolution detects experiment |
| CN111227988A (en) * | 2020-03-17 | 2020-06-05 | 中国科学院深圳先进技术研究院 | Brain stereotactic injection device |
| CN111888036A (en) * | 2020-07-31 | 2020-11-06 | 福建医科大学附属第一医院 | Fixing structure of rat brain stereotaxic instrument |
| CN113141766A (en) * | 2021-04-16 | 2021-07-20 | 中国科学院深圳先进技术研究院 | Electrophysiological experiment shielding box |
| CN113141766B (en) * | 2021-04-16 | 2022-10-14 | 中国科学院深圳先进技术研究院 | Electrophysiological experiment shielding box |
| CN113598801A (en) * | 2021-08-12 | 2021-11-05 | 徐州医科大学 | Head fixing device for PET-CT scanning anesthesia rat of small animal |
| CN113598801B (en) * | 2021-08-12 | 2024-02-27 | 徐州医科大学 | Head fixing device for PET-CT scanning anesthetized rats of small animals |
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| CN108478305B (en) | 2024-04-19 |
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