Summary of the invention
In order to solve these deficiencies of prior art, the utility model provides a kind of new seal ring, and a kind of detection device that adopts the sealing circle is provided, and can prevent effectively that liquid from leaking from container, improved the up-to-standard rate of product.
The utility model provides a kind of seal ring, the sealing circle comprises the sealed outer ring that contains upper surface and lower surface, with the sealing inner ring that contains internal surface and outer surface, wherein the angle between the internal surface of the lower surface of sealed outer ring and sealing inner ring is spent less than 180 greater than 90 degree.
In a preferred mode, when the lower surface of sealed outer ring was horizontal plane, the internal surface of sealing inner ring and the angle between the horizontal plane were spent less than 180 greater than 90 degree.
In the preferred mode, the angle between the internal surface of the lower surface of sealed outer ring and sealing inner ring is spent less than 180 greater than 100 degree.In the preferred mode, the angle between the internal surface of the lower surface of sealed outer ring and sealing inner ring is 120 degree.
In a preferred mode, comprise the structure of at least one projection on the lower surface of sealed outer ring.
Preferred, this projection is triangle or circle or rectangle.
In the more preferred mode, this raised structures can be continuous raised ring, also can be discontinuous projection.
Better, the lower surface of this raised ring and sealed outer ring lower surface parallel, the height homogeneous of projection.
The utility model also provides a kind of detection device, this detection device comprises can detect the reagent that whether contains analyte in the sample, collect cup and the bowl cover that detects sample for one, and the seal ring that matches of the rim of a cup that is positioned at bowl cover and cup, the sealing circle comprises the sealed outer ring that contains upper surface and lower surface, with the sealing inner ring that contains internal surface and outer surface, wherein the angle between the internal surface of the lower surface of sealed outer ring and sealing inner ring is spent less than 180 greater than 90 degree.
In the preferred mode, the lower surface of the sealed outer ring of this detection device also comprises the structure of at least one projection.
Preferred, the lower surface of sealed outer ring comprises continuous raised ring.
In another preferred mode, the rim of a cup of this detection device comprises glass edge and glass ridge, and when the sealed circle of vessel port of collecting the detection sample sealed, the lower surface of sealing outer ring contacted with the cup edge, and the outer surface of sealing inner ring contacts with a glass ridge.
A preferred mode of execution is that the outer surface of sealing inner ring is that line or face contact with the cup ridge.In a preferred mode of execution, the angle between the internal surface of the lower surface of sealed outer ring and sealing inner ring is 120 degree, and the lower surface of sealed outer ring comprises continuous highly homogeneous raised ring, and raised ring contacts with the cup crestal line.
The beneficial effect that the utility model is obtained is: exist between the internal surface of the lower surface of sealed outer ring and sealing inner ring one greater than 90 degree the angles less than 180 degree, the internal surface of sealing inner ring is an inclined-plane with respect to the lower surface of sealed outer ring, this inclined-plane contacts with the cup ridge of vessel port, and consequent interference effect can produce the better seal effect.In addition, increase the structure of a projection on the lower surface of sealed outer ring, the cup of this projection and vessel port can further prevent the leakage of liquid sample along being in contact with one another, and plays the effect of secondary seal.
Embodiment
Structure or these employed technical terms to seal ring 1 and detection device is described further below.
Detect
Detect the expression chemical examination or test a kind of material or whether material exists, such as, but be not limited to this, the metabolin of chemical substance, organic compound, inorganic compound, metabolism product, medicine or drug metabolite, organic organization or organic organization, nucleic acid, protein or polymer.In addition, detect the quantity of expression test substances or material.Furtherly, immune detection, chemical detection, enzyme detection etc. are also represented in chemical examination.
Sample
The sample of the utility model indication refers to that those can be used for detecting, chemically examining or diagnose the material that whether has analyte of interest matter.Sample can be that for example, liquid sample, liquid sample can comprise blood, blood plasma, serum, urine, saliva and various juice, can also comprise that solid sample and semi-solid samples are through anticipating the liquid solution that the back forms.The sample of collecting can be used for methods such as immune detection, chemical detection, enzyme detection and detect whether there is analyte.
Seal ring
Seal ring 1 described in the utility model is used in the sealing of two surface of contact, prevents that liquid sample from leaking.Sealed picture 1 comprises sealing inner ring 3 and sealed outer ring 2, and sealing inner ring 3 and sealed outer ring 2 can be once Cheng Mo, also can be to be combined together to form complete seal ring 1 by form such as hinged.Seal ring 1 cooperates with urine cup 100, realizes by interference fit.So-called interference fit, the size that is meant seal ring 1 deducts the algebraic step of the size gained of the cup that matches and bears, be called interference, also claim negative clearance, that is to say, when the gap between seal ring that mutually combines 1 that base dimension is identical and cup (urine cup 100) tolerance range is negative, be interference fit between the two.Interference fit is mainly used in the fastening connection that does not allow relative movement between the two, as the cooperation of urine cup 100 cups and seal ring 1.Because the size of cup is bigger than the size of seal ring 1, so need to adopt the way of pressurization to assemble, this pressure does not need very big, and the technician or the public can assemble the two under normal conditions.
Sealing inner ring 3 comprises internal surface 32 and outer surface 31,2 of sealed outer rings have upper surface 21 and lower surface 22, the internal surface 32 of the lower surface 22 of sealed outer ring and sealing inner ring can contact, can form certain included angle between two planes, this angle can be 90 to spend to angle arbitrarily between 180 degree.Form an obtuse angle between the internal surface 32 of the lower surface 22 of sealed outer ring and sealing inner ring, its seal action is better than forming right angle or acute angle between the two.This be because, when the internal surface 32 of sealing inner ring exists as an inclined-plane with respect to sealed outer ring 2, when the cup ridge 123 of internal surface 32 that seals inner ring and rim of a cup contacts, along with extruding or rotation, gap between the two is more and more littler, and in general the material of seal ring 1 is rubber-like, as rubber etc., and cup generally is to be made by the material with suitable hardness, as plastics etc.Wherein the size of seal ring 1 is come for a short time than the size of urine cup 100 cups, in the time of both cooperatively interact, can be subjected to the power of vertical pressure and rotation, active force that produces between the collection cavity 120 of seal ring 1 and cup and reaction force can make the cup with certain degree of hardness " fall into " part of entering toward rubber-like seal ring 1, cause the generation of magnitude of interference at last, make sealing effect good especially.Comprise the bowl cover 110 of seal ring 1, be in sealing state by this interference fit and cup exactly.The angle that exists between the internal surface 32 of sealing inner ring and the lower surface 22 of sealed outer ring makes the internal surface 32 that seals inner ring more be easy to generate interference fit when contacting with a cup ridge 123.In the preferred mode, the lower surface 22 of sealed outer ring is a horizontal plane, and the angle between the internal surface 32 of sealing inner ring and the lower surface 22 of sealed outer ring is spent less than 180 greater than 100 degree.Needed power when the internal surface 32 that the number of degrees that tilt can influence the sealing inner ring produces the interference effect with sealed thing when contacting, same active force, inclination is big more, sealed thing is also just big more to the reaction force that seal ring 1 produces, also more be easy to generate the interference effect, thereby, adopt bigger inclination can improve sealability.But, the excessive inconvenience that also can cause when exerting pressure of inclination, thus 100 spend to 180 the degree scopes in inclination be preferred.Better, the angle between the internal surface of sealing inner ring and the lower surface of sealed outer ring is 120 degree.
The lower surface 22 of sealed outer ring can also comprise the structure of at least one projection.With the engagement process of rim of a cup 121 in, the projection of existence can cooperate along 124 with the cup of rim of a cup, plays the effect of secondary seal.Owing to there is the structure of projection, seal ring 1 stressed back in engagement process makes the projection of seal ring 1 be affixed to rim of a cup 121 by means of sealing inner ring 3 component radially, along playing the effect that prevents the liquid sample seepage on 124 directions, has improved sealability at cup.In a concrete mode of execution, the number of projection can be one, also can be 2 or a plurality of.The number of projection can influence the performance of sealing, but is not a crucial factor.Projection can be leg-of-mutton projection, also can be circular projection, can also be the projection of rectangle.Surface of contact when the shape decision projection of projection cooperates with the cup edge of rim of a cup, leg-of-mutton projection is the line contact with contacting of cup edge, circular projection with rectangle is that face contacts with contacting of cup edge.In general, the width on cup edge is all smaller, adopts leg-of-mutton projection, with cup when contact, can produce the surface of contact or even the Line of contact of a minimum, can guarantee that whole projection all drops on glass along last, plays the better seal effect.The material of projection is consistent with seal ring 1, has elasticity, thereby in contact cup edge, if the strength of extruding is excessive, the shape of projection may change, cause projection and the surface of contact or the line on cup edge to be distorted, but changing a little on the shape for lugs can not influence the sealing effect of projection to the cup edge.Projection can be continuous, also can be discontinuous.Projection is the projection of ring sealed outer ring 2 whole figure, also can be the projection on each scattered point on the sealed outer ring 2.Comparatively speaking, continuous projection has better sealing.Better, the structure of projection is continuous raised ring, forms the raised structures of a circle on the lower surface 22 of sealed outer ring.More preferred, the lower surface of raised ring is parallel with the lower surface of sealed outer ring 22, the height homogeneous of projection.Such raised ring with cup when 124 contact, form a complete circle sealing at cup on along 124, along working on each position of 124, can more effectively must prevent the leakage or the seepage of liquid sample at cup, make sealability better.In a comparatively preferred mode, seal ring 1 can be positioned at the bowl cover 110 of detection device, cooperates with the rim of a cup 121 of cup to reach sealing.Rim of a cup 121 comprises glass ridge 123 and cup along 124, and seal ring 1 can seal rim of a cup 121 on along 124 at cup ridge 123 or cup.The outer surface 31 of sealing inner ring can contact with cup ridge 123, reaches sealing state by interference fit.The lower surface 22 and the cup of sealed outer ring contact along 124.More preferred, the outer surface 31 of figure contacts for line or the face contact with cup ridge 123 in the sealing.In a preferred mode of execution, the angle between the internal surface 32 of the lower surface 22 of sealed outer ring and sealing inner ring is 120 degree, and the lower surface 22 of sealed outer ring comprises continuous highly homogeneous raised ring, and raised ring contacts with the cup crestal line.
The material of seal ring 1 can be rubber, fluorine rubber, silicone rubber, hydrogenation butyronitrile rubber, acrylate rubber, chlorohydrin rubber, haloflex graphite, the industrial material that is usually used in making seal ring 1 or seal ring of teflon, molybdenum disulfide, polyimide, bronze powder and carbon black or the like.Seal ring 1 can be an O type circle, also can be Y type figure, and the main shape of the device of sealing as required of its shape decides.
Analyte
Can analyze any analyte with apparatus and method of the present utility model.The example of the analyte of the enough apparatus and method stable detection of the present invention of energy comprises (but not only comprising) human chorionic gonadotrophin (hCG), lutropin (LH), ovarian stimulation element (FSH), hepatitis C virus (HCV), hepatitis B (HBV), hepatitis B surface antigen, the medicine of AIDS virus and any abuse.Analyte can detect in any liquid or liquefied sample, urine for example, saliva, saliva, blood, blood plasma, perhaps serum.The example of other analyte also has the acid of flesh ammonia acid anhydride, bilirubin, nitrite, protein (nonspecific), blood, leucocyte, blood sugar, heavy metal and toxin, the bacterium composition is (for example, special protein and the sugar of the bacterium of particular type, colon bacillus 0157: H7 for example, staphylococcus aureus, salmonella, C.perfringens, campylobacter, listeria monocytogenes, enteritis vibrios, perhaps cured shape bacillus).Any other analyte of suitable lateral flow assay form can detect with this device.
Analyte can also be some haptens materials, and these haptens comprise drugs (as drug abuse)." drug abuse " (DOA) is meant that the non-medical destination uses medicine (playing the paralysis nerve usually).Abuse these medicines and can cause body ﹠ mind to suffer damage, produce dependence, habit-forming and/or dead.The example of drug abuse comprises cocaine; Amphetamine (for example, black beauty, white amphetamine tablet, dextroamphetamine, dexie, Beans); Crystal methamphetamine (crank, meth, crystal, speed); Barbiturate (as Valium, Roche Pharmaceuticals, Nutley, New Jersey); Sedative (paramedicines of promptly sleeping); Lysergic acid diethylamide (LSD); Inhibitor (downers, goofballs, barbs, blue devils, yellow jackets, methaqualone); The anti-antidepressant of tricyclic antidepressants (TCA, i.e. imipramine, amitriptyline and doxepin); Hog (PCP); Tetrahydrocannabinol (THC, pot, dope, hash, weed, etc.); Opiate (being morphine, opium, codeine, heroin, the hydroxyl dihydrocodeinone); Anxiolytic and hypnotic sedative agent, anxiolytic is that a class is mainly used in anxiety reduction, nervous, frightened, set the mind at rest, have the medicine of hypnosis sedation concurrently, comprise Benzodiazepines (benzodiazepines, BZ), atypia BZ class, merge phenodiazine NB23C class, the tall and erect class of benzene nitrogen, the part class of BZ acceptor, open loop BZ class, diphenylmethane derivatives, the piperazine carboxylic acid salt, the piperidine carboxylic acid salt, Kui azoles quinoline ketone, thiazine and thiazole, other heterocyclic, imidazole type calmness/analgesic, propanediol derivative-carbamates, aliphatic compound, anthracene derivative etc.Use this device also can be used to detect and belong to medical usage but the detection of overdose easily, as tricyclic antidepressant (imipramine or analog) and Paracetamol etc.Can resolve into different small-molecule substances after these medicines are absorbed by the body, these small-molecule substances are present in the body fluid such as blood, urine, saliva, sweat or there is above-mentioned small-molecule substance in part body fluid.
Detection device
Detection device is to be used to collect liquid, such as urine etc., and analyzes the situation of its contained analyte (as drugs and metabolin thereof).Detection device generally comprises one and has the bowl cover that opening is used to collect the cup of liquid sample and seals opening.Detection device can be made by multiple difformity and different materials, for example the plastics of all size.Can install the seal ring 1 that is disclosed by the utility model on the detection device and solve defective of the prior art, in addition, the detection urine cup of other prior aries also can be installed the sealing circle, and for example the drugs described in U.S.'s publication application US2006/0198758A1 detect urine cup; Liquid sample described in the utility model patent ZL200420115960.4 of China's bulletin detects cup.Persons skilled in the art are expected the detection urine cup combination with other type easily after reading the utility model.
Below in conjunction with concrete accompanying drawing examples of implementation of the present utility model are described in detail.These specific embodiment only are limited the enumerating under the utility model spirit, do not get rid of one of ordinary skill in the art prior art and the utility model in conjunction with and other specific embodiments of producing.
Embodiment 1
As Fig. 1, shown in 2, seal ring 1 in the utility model comprises sealed outer ring 2 and sealing inner ring 3, sealed outer ring 2 comprises sealed outer ring upper surface 21 and sealed outer ring lower surface 22, also comprise a uniform raised ring 20 on the lower surface 22 of sealed outer ring, Fig. 3 comprises sealing inner ring upper surface outer surface 31 and sealing inner ring internal surface 32 in the sealing.The lower surface 22 of sealed outer ring is a level, and the angle between sealing inner ring internal surface 32 and the sealed outer ring lower surface 22 is 120 degree.When sealed picture 1 was used for package seal checker, the internal surface 32 of sealing inner ring 3 can form interference fit with surface of contact, plays good seal action.Raised ring 20 is height homogeneous that are positioned on the sealed outer ring lower surface 22, and cross section is leg-of-mutton ring structure, and when raised ring 20 was collided with surface of contact, raised ring 20 can be close to surface of contact, and detection device is produced secondary seal.
Embodiment 2
As Fig. 3, shown in 4 and 5, the utility model can be the seal ring 1 that is used for urine cup 100, urine cup 100 comprises bowl cover 110, collection cavity 120 and test chamber 130, bowl cover 110 and collection cavity 120 can be worked in coordination by bowl cover screw thread 111 and cup screw thread 122, can place in the test chamber 130 and can detect reagent strip or other devices that whether contains analyte in the sample.Seal ring 1 can be arranged in the inwall 112 of bowl cover 110, the outer surface 31 of sealed outer ring 2 and upper surface 21 and the bowl cover inwall 112 in the sealing abut against each other, be difficult for coming off in bowl cover 110, the seal arrangement with bowl cover 110 forms a whole seals collection cavity 120.The sealing of 11 pairs of collection cavitys 120 of seal ring realizes by two-layer sealing.One deck sealing is, sealing inner ring internal surface 32 contacts with the cup ridge 123 of collection cavity 120, because making the material of seal ring 1 is the rubber elastomeric material, thereby the line by the inclined-plane contacts on cup ridge 123 and sealing inner ring internal surface 32, cup ridge 123 1 whole circles are produced the effect of a sealing, angle between sealing inner ring internal surface 32 and the sealed outer ring lower surface 22 is 120 degree, and this angle not only can use minimum power to produce enough magnitude of interference, and realizes than being easier on technology.Another layer sealing is.Sealed outer ring lower surface 22 also comprises a raised ring 20, and with when collection cavity 120 contacts, the cup of raised ring and rim of a cup 121 meets along 124, forms another layer sealing at cup on along 124.In addition, raised ring 20 be leg-of-mutton, and leg-of-mutton top and cup be along 124 surface of contact that can form a minimum, or even Line of contact, this along 124, can play seal action for the less cup of width to the full extent.