CN1985921B - Chinese medicine composition for treating common cold and its preparing method - Google Patents

Abstract

The present invention provides a kind of Chinese medicine for dispersing wind, clearing away heat and toxic material and relieving sore throat and its preparation process. The Chinese medicine is prepared with honeysuckle, skullcap root, schizonepeta herb, cape jasmine, forsythia and other nine kinds of Chinese medicinal materials. The Chinese medicine materials are extracted to obtain active components and further prepared into oral liquid, tablet, capsule, granule, dripping pill or other forms for fitting different patients.

Description

A kind of Chinese medicine composition for the treatment of flu and preparation method thereof

Technical field

The present invention relates to field of medicaments, particularly relate to a kind of Chinese medicine composition for the treatment of flu and preparation method thereof.

Background technology

Flu is a kind of commonly encountered diseases and frequently-occurring disease, and especially at spring, winter sickness rate height, its symptom is nasal obstruction, watery nasal discharge, headache, cough, heating etc., makes us feeling very uncomfortable, can have influence on normal life when serious.Mostly flu is the upper respiratory tract infection that caused by virus, and cause of disease is rhinovirus, coronavirus, parainfluenza virus, adenovirus etc.Adult's flu is caused by rhinovirus and coronavirus mostly.The rhinovirus transmissibility is very strong, and the infection rate height how at autumn, throttling in spring row, is the main virus that causes flu.Coronavirus is comparatively common with winter.Also there is not the specific treatment medicine so far.Medicines such as Moroxydine, vidarabine, polyinosini have certain inhibitory action to some virus breeding, but can not cause that the virus of common cold is all effective to all.

At present commercially available Coritab is numerous in variety, mostly is compound preparation, and compound preparation mainly is to utilize between the various medicines to have synergism, brings into play the advantage of each medicine, reaches the purpose of symptomatic treatment.Though aspect the symptoms such as the headache that chemicals causes because of flu in alleviation, heating, cough, nasal obstruction, watery nasal discharge, sneeze curative effect is preferably arranged, but it mainly is a relief of symptoms, and majority of compounds make cold medicine brought that side effect such as drowsiness also can not be ignored.The Chinese medicine of treatment flu at present is a lot, and dosage form is also varied, existing onset slowly pill, also onset drop pill, injection, injectable powder rapidly arranged; Existingly replace the granule of tea-drinking, also the tablet of taking convenience arranged; Effervescent in the existing patient's of satisfying curiosity, also suitable children's's suppository arranged, but from present clinical practice curative effect, no matter be single preparations of ephedrine or compound preparation, curative effect of medication is low still to be one of principal element that influence patient's use.At the natural degree height of Chinese medicine, side effect is low; In the selection that the combination drug curative effect is high and pair is big, the patient often abandons the low Chinese medicine of toxic and side effects and selects the bigger combination drug of side effect to treat flu, in the hope of quick relief of symptoms.

Summary of the invention

The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of flu.

Another object of the present invention provides a kind of preparation method for the treatment of the Chinese medicine composition of flu.

Pharmaceutical composition of the present invention is to be made by Flos Lonicerae, Radix Scutellariae, Herba Schizonepetae, Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Herba Menthae, Periostracum Cicadae, Radix Saposhnikoviae, Radix Glycyrrhizae.

In the pharmaceutical composition of the present invention, Fructus Gardeniae (parched) is Fructus Gardeniae (stir-fry); Bombyx Batryticatus is Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens).

The consumption of each component of medicine of the present invention and proportioning obtain with Test Summary by groping in a large number through the inventor, and each component raw material medicine all has curative effect preferably at the following weight parts ratio range: 36～145 parts of Flos Loniceraes, 36～145 parts of Radix Scutellariaes, 36～145 parts of Herba Schizonepetae, 36～145 parts of Fructus Gardeniaes, 36～145 parts of Fructus Forsythiaes, 36～145 parts of Radix Scrophulariaes, 22～85 parts of Bombyx Batryticatus, 55～215 parts of Radix Rehmanniae, 11～45 parts of Rhizoma Belamcandae, 22～85 parts of Radix Platycodoniss, 22～85 parts of Herba Menthaes, 22～85 parts of Periostracum Cicadaes, 22～85 parts of Radix Saposhnikoviaes, 11～45 parts in Radix Glycyrrhizae.

Preferred each component raw material medicine of pharmaceutical composition of the present invention all has curative effect preferably at the following weight parts ratio range: 53.54～86.70 parts of Flos Loniceraes, 53.54～86.70 parts of Radix Scutellariaes, 53.54～86.70 parts of Herba Schizonepetae, 53.54～86.70 parts of Fructus Gardeniaes, 53.54～86.70 parts of Fructus Forsythiaes, 53.54～86.70 parts of Radix Scrophulariaes, 33.57～51.55 parts of Bombyx Batryticatus, 86.27～129.81 parts of Radix Rehmanniae, 17.54～26.70 parts of Rhizoma Belamcandae, 33.57～51.55 parts of Radix Platycodoniss, 33.57～51.55 parts of Herba Menthaes, 33.57～51.55 parts of Radix Saposhnikoviaes, 33.57～51.55 parts of Periostracum Cicadaes, 17.54～26.70 parts in Radix Glycyrrhizae.

Each component raw material medicine of preferred pharmaceutical composition of the present invention all has curative effect preferably at the following weight parts ratio range: 69～75 parts of Flos Loniceraes, 69～75 parts of Radix Scutellariaes, 69～75 parts of Herba Schizonepetae, 69～75 parts of Fructus Gardeniaes, 69～75 parts of Fructus Forsythiaes, 69～75 parts of Radix Scrophulariaes, 40～47 parts of Bombyx Batryticatus, 100～115 parts of Radix Rehmanniae, 20～25 parts of Rhizoma Belamcandae, 40～47 parts of Radix Platycodoniss, 40～47 parts of Herba Menthaes, 40～47 parts of Periostracum Cicadaes, 40～47 parts of Radix Saposhnikoviaes, 20～24 parts in Radix Glycyrrhizae.

Best each component raw material medicine of pharmaceutical composition of the present invention all has curative effect preferably at the following weight parts ratio range: 72 parts of Flos Loniceraes, 72 parts of Radix Scutellariaes, 72 parts of Herba Schizonepetae, 72 parts of Fructus Gardeniaes, 72 parts of Fructus Forsythiaes, 72 parts of Radix Scrophulariaes, 43 parts of Bombyx Batryticatus, 108 parts of Radix Rehmanniae, 22 parts of Rhizoma Belamcandae, 43 parts of Radix Platycodoniss, 43 parts of Herba Menthaes, 43 parts of Periostracum Cicadaes, 43 parts of Radix Saposhnikoviaes, 22 parts in Radix Glycyrrhizae.

The preparation of the active component of the present composition and preparation can adopt following method: one or several use in conjunction preparations in extraction, water extraction, decoction and alcohol sedimentation technique, extraction, infusion process, percolation, reflux extraction, continuous backflow extraction method, the macroreticular resin absorbing method.For example, can be with these crude drug pulverizes; Also can be with these medicines decocting together, the condensed water decocting liquid is made decoction then; But in order to make each crude drug of this medicine bring into play drug effect better, the present invention preferably adopts following technology to extract to raw material, but this can not limit protection scope of the present invention.

The weight portion proportioning that following medicine activity component extracts raw materials used medicine can be any proportioning, and preferred feedstock medicine weight portion proportioning is a dosage range provided by the present invention.

The preparation method of pharmaceutically active active component of the present invention is as follows:

A. 36～145 parts of extracting honeysuckles, 36～145 parts of Radix Scutellariaes, 36～145 parts of Herba Schizonepetae, 36～145 parts of Fructus Gardeniaes, 36～145 parts of Fructus Forsythiaes, 36～145 parts of Radix Scrophulariaes, 22～85 parts of Bombyx Batryticatus, 55～215 parts of Radix Rehmanniae, 11～45 parts of Rhizoma Belamcandae, 22～85 parts of Radix Platycodoniss, 22～85 parts of Herba Menthaes, 22～85 parts of Periostracum Cicadaes, 22～85 parts of Radix Saposhnikoviaes, 11～45 parts in Radix Glycyrrhizae are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 1～12 times of amount alcohol reflux 1～3 time, each 1～3 hour, concentration of ethanol was 30%～95%, reclaimed ethanol, was concentrated into relative density 1.00～1.35 in the time of 45～85 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 1～8 times of water gaging, soak after 0.5～5 hour, adopted steam distillation 1～8 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 1～3 time, decoct 0.5～3 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.00～1.35 in the time of 50～85 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 10～85%, left standstill 4～48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.00～1.45 in the time of 50～90 ℃, drying gets medicated powder II; Merge medicated powder I, medicated powder II, be ground into fine powder.

Preferably, the preparation method of pharmaceutically active active component of the present invention is as follows:

A. 53.54～86.70 parts of extracting honeysuckles, 53.54～86.70 parts of Radix Scutellariaes, 53.54～86.70 parts of Herba Schizonepetae, 53.54～86.70 parts of Fructus Gardeniaes, 53.54～86.70 parts of Fructus Forsythiaes, 53.54～86.70 parts of Radix Scrophulariaes, 33.57～51.55 parts of Bombyx Batryticatus, 86.27～129.81 parts of Radix Rehmanniae, 17.54～26.70 parts of Rhizoma Belamcandae, 33.57～51.55 parts of Radix Platycodoniss, 33.57～51.55 parts of Herba Menthaes, 33.57～51.55 parts of Radix Saposhnikoviaes, 33.57～51.55 parts of Periostracum Cicadaes, 17.54～26.70 parts in Radix Glycyrrhizae are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2～10 times of amount alcohol reflux secondaries, each 1～2 hour, concentration of ethanol was 40～90%, reclaimed ethanol, was concentrated into relative density 1.02～1.30 in the time of 45～80 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 1～7 times of water gaging, soak after 1～4 hour, adopted steam distillation 1～7 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1～2 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20～80%, left standstill 8～36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.00～1.30 in the time of 60～80 ℃, drying gets medicated powder II: merge medicated powder I, medicated powder II, be ground into fine powder.

Further preferred, the preparation method of pharmaceutically active active component of the present invention is as follows:

A. 69～75 parts of extracting honeysuckles, 69～75 parts of Radix Scutellariaes, 69～75 parts of Herba Schizonepetae, 69～75 parts of Fructus Gardeniaes, 69～75 parts of Fructus Forsythiaes, 69～75 parts of Radix Scrophulariaes, 40～47 parts of Bombyx Batryticatus, 100～115 parts of Radix Rehmanniae, 20～25 parts of Rhizoma Belamcandae, 40～47 parts of Radix Platycodoniss, 40～47 parts of Herba Menthaes, 40～47 parts of Periostracum Cicadaes, 40～47 parts of Radix Saposhnikoviaes, 20～24 parts in Radix Glycyrrhizae are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3～7 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 60～70%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3～5 times of water gagings, soak after 1～2 hour, adopted steam distillation 2～4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1～2 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20～80%, left standstill 8～36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II; Merge medicated powder I, medicated powder II, be ground into fine powder.

Best, the preparation method of pharmaceutically active active component of the present invention is as follows:

A. 72 parts of extracting honeysuckles, 72 parts of Radix Scutellariaes, 72 parts of Herba Schizonepetae, 72 parts of Fructus Gardeniaes, 72 parts of Fructus Forsythiaes, 72 parts of Radix Scrophulariaes, 43 parts of Bombyx Batryticatus, 108 parts of Radix Rehmanniae, 22 parts of Rhizoma Belamcandae, 43 parts of Radix Platycodoniss, 43 parts of Herba Menthaes, 43 parts of Periostracum Cicadaes, 43 parts of Radix Saposhnikoviaes, 22 parts in Radix Glycyrrhizae are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II; Merge medicated powder I, medicated powder II, be ground into fine powder.

Active component of the present invention can be made any preparation on the pharmaceutics; The active component of medicine of the present invention can add various conventional adjuvant required when preparing different dosage form, be prepared into any common formulations as disintegrating agent, lubricant, binding agent etc. with the method for Chinese medicinal of routine, as tablet, sugar coated tablet, film coated tablet, enteric coated tablet, powder, capsule, soft capsule, pill, electuary, oral liquid, granule, drop pill, micropill, intramuscular injection agent, instillation, unguentum, ointment, plaster etc.; The best is made tablet, drop pill, oral liquid, granule, capsule, soft capsule.

The preparation method of medicinal tablet of the present invention, wherein the medicated powder I that makes of step b and medicated powder II mixing fine powders, volatile oil mix tabletting with tablet adjuvant commonly used.

Preferably, the preparation method of tablet of the present invention, the medicated powder I and the medicated powder II mixing fine powders that make of step b wherein, the combination of one or more of adjuvants such as adding starch, dextrin, lactose, PVP, carboxymethyl starch sodium, mix homogeneously, adding concentration is 8～75% alcohol granulations, and consumption is 4～60% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add one or several combinations in magnesium stearate, silica gel, the Polyethylene Glycol, mix homogeneously, tabletting, coating or coating not promptly get tablet.

Further preferred, the preparation method of tablet of the present invention, the medicated powder I and the medicated powder II mixing fine powders that make of step b wherein, the combination of one or more of adjuvants such as adding starch, dextrin, lactose, PVP, carboxymethyl starch sodium, mix homogeneously, adding concentration is 10～70% alcohol granulations, and consumption is 5～50% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add one or several combinations in magnesium stearate, silica gel, the Polyethylene Glycol, mix homogeneously, tabletting, coating or coating not promptly get tablet.

Best, the preparation method of tablet of the present invention, wherein the medicated powder I and the medicated powder II mixing fine powders that make of step b, add starch, amount of starch is medicated powder I and medicated powder II weight 0.4～2 times, mix homogeneously, adding concentration is 10～70% alcohol granulations, and consumption is 5～50% of medicated powder and a starch consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously, tabletting, coating promptly gets tablet.

The preparation method of drop pill of the present invention, wherein the medicated powder I that makes of step b and medicated powder II mixing fine powders, volatile oil mix drop pill with drop pill adjuvant commonly used.

Preferably, the preparation method of drop pill of the present invention, wherein the medicated powder I that makes of step b and medicated powder II mixing fine powders, volatile oil, mix homogeneously, add the one or any combination in polyethylene glycol 6000, Macrogol 4000, the polyethylene glycol 1500, heating dissolves, and adopting a speed is 15～90/min, splash in the condensed fluid, promptly get drop pill.

Further preferred, the preparation method of drop pill of the present invention, wherein the medicated powder I that makes of step b and medicated powder II mixing fine powders, volatile oil, mix homogeneously, add polyethylene glycol 6000, the one or any combination of Macrogol 4000, heating dissolves, and adopting a speed is 20～80/min, splash in the condensed fluid, promptly get drop pill.

Further preferred, the preparation method of drop pill of the present invention, wherein the medicated powder I that makes of step b and medicated powder II mixing fine powders, volatile oil, mix homogeneously, the polyethylene glycol 6000 of 1～30 times of amount of adding medicated powder: Macrogol 4000=1～5: 1～4 mixture, heating dissolves, adopting a speed is 25～75/min, splash into liquid Paraffin, or methyl-silicone oil or methyl-silicone oil: liquid Paraffin=1～4: in 1～3 the condensed fluid, promptly get drop pill.

Best, the preparation method of drop pill of the present invention, wherein the medicated powder I that makes of step b and medicated powder II mixing fine powders, volatile oil, mix homogeneously adds the polyethylene glycol 6000 of 20 times of amounts of medicated powder: the mixture of Macrogol 4000=3: 2, and heating dissolves, adopting a speed is 40/min, splash into liquid Paraffin, or methyl-silicone oil: liquid Paraffin is in 3: 1 the condensed fluid, promptly to get drop pill.

The capsular preparation method of the present invention, wherein the active component medicated powder I and the medicated powder II mixing fine powders that make of step b sprays into volatile oil, and mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Preferably, the capsular preparation method of the present invention, wherein add adjuvant in the medicated powder I that makes of step b and the medicated powder II mixing fine powders, wherein adjuvant is selected from one or more combination of adjuvants such as starch, dextrin, lactose, PVP, carboxymethyl starch sodium, mix homogeneously, adding concentration is 8～75% alcohol granulations, and consumption is 4%～60% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add adjuvant, adjuvant is selected from one or several combinations in magnesium stearate, silica gel, the Polyethylene Glycol, and mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Further preferred, the capsular preparation method of the present invention, wherein add adjuvant in the medicated powder I that makes of step b and the medicated powder II mixing fine powders, adjuvant is selected from one or more combination of starch, dextrin, lactose, the weight of used adjuvant is medicated powder I and medicated powder II weight sum 0.5～6 times, mix homogeneously, adding concentration is 10～70% alcohol granulations, consumption is 5%～50% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add lubricant, lubricant is selected from one or several combinations in magnesium stearate, silica gel, the Polyethylene Glycol, weight with lubricator be 0.1～8% of medicated powder I and medicated powder II weight sum, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Add starch in medicated powder I that step b makes and the medicated powder II mixing fine powders, the weight of starch is medicated powder I and medicated powder II weight sum 0.5～2 times, mix homogeneously, and adding concentration is 20～30% alcohol granulations, consumption is 10%～30% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, the weight of magnesium stearate is 0.1～2% of medicated powder I and medicated powder II weight sum, and mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

The preparation method of granule of the present invention, wherein the medicated powder I that makes of step b and medicated powder II mixing fine powders and granule adjuvant commonly used is granulated, and with particle drying, sprays into volatile oil, promptly gets granule.

Preferably, the preparation method of granule is dripped in the present invention, one or more the combination that wherein adds adjuvants such as cane sugar powder, soluble starch, dextrin, ring adjuvant in the medicated powder I that makes of step b and the medicated powder II mixing fine powders, water is granulated, consumption is 8～50% of medicated powder and a supplementary product consumption, with particle drying, spray into volatile oil, promptly get granule.

Further preferred, the preparation method of granule of the present invention, one or more the combination that wherein adds adjuvants such as cane sugar powder, soluble starch, dextrin, ring adjuvant in the medicated powder I that makes of step b and the medicated powder II mixing fine powders, the amount of used adjuvant is medicated powder I and medicated powder II weight 0.3～6 times, mix homogeneously, and water is granulated, consumption is 10～30% of medicated powder and a supplementary product consumption, with particle drying, spray into volatile oil, promptly get granule.

Best, the preparation method of granule of the present invention, one or both the combination that wherein adds soluble starch, cyclodextrin adjuvant in the medicated powder I that makes of step b and the medicated powder II mixing fine powders, the amount of used adjuvant is medicated powder I and medicated powder II weight 0.4～3 times, and mix homogeneously adds water and granulates, consumption is 10～30% of medicated powder and a supplementary product consumption, with particle drying, spray into volatile oil, promptly get granule.。

Preparation of soft capsule method of the present invention, wherein the volatile oil that makes of step b adds the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 5～30min, volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II mixing fine powders, mixing with homogenize machine homogenize 10～60min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 10～60min, promptly gets soft capsule content; Described substrate is a kind of or combination in any in vegetable oil, Polyethylene Glycol or the Tween 80; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Preferably, preparation of soft capsule method of the present invention, wherein the volatile oil that makes of step b adds the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 8～20min, volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 20～40min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 20～40min, promptly gets soft capsule content; Described substrate is a kind of or combination in any in vegetable oil, Polyethylene Glycol or the Tween 80; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Further preferred, preparation of soft capsule method of the present invention, wherein the volatile oil that makes of step b adds the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 10min, volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 5～40%, volatile oil 0.01～5%, substrate 10～50%, glycerol 0.25～8%, water 1～10%, surplus are the soft capsule content of tween, and described substrate is a kind of or combination in any in vegetable oil, Polyethylene Glycol or the Tween 80; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Best, the preparation method of drop pill of the present invention, wherein the volatile oil that makes of step b adds the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 10min, volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 12.61%, volatile oil 0.14%, substrate 25%, glycerol 1.25%, water 5%, the soft capsule content of tween 56%, described substrate is a kind of or combination in any in vegetable oil, Polyethylene Glycol or the Tween 80; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Among the present invention, vegetable oil is the one or any combination in Oleum Brassicae campestris, Oleum Glycines, Oleum Arachidis hypogaeae semen, Oleum Helianthi, Oleum Gossypii semen, Semen Maydis oil, Oleum sesami, olive oil, the safflower oil.

Preferred vegetable oil is the one or any combination in Oleum Glycines, Oleum Arachidis hypogaeae semen, the olive oil.

Drop pill of the present invention can adopt following method preparation, comprises the steps:

A. 36～145 parts of extracting honeysuckles, 36～145 parts of Radix Scutellariaes, 36～145 parts of Herba Schizonepetae, 36～145 parts of Fructus Gardeniaes, 36～145 parts of Fructus Forsythiaes, 36～145 parts of Radix Scrophulariaes, 22～85 parts of Bombyx Batryticatus, 55～215 parts of Radix Rehmanniae, 11～45 parts of Rhizoma Belamcandae, 22～85 parts of Radix Platycodoniss, 22～85 parts of Herba Menthaes, 22～85 parts of Periostracum Cicadaes, 22～85 parts of Radix Saposhnikoviaes, 11～45 parts in Radix Glycyrrhizae are standby;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 45～85% ethanol extractions 1～4 time, and each 0.5～4 hour, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 1～4 time, each 0.5～4 hour, collecting decoction, filter, filtrate is concentrated into that relative density is 1.03～1.25 in the time of 50～90 ℃, adding ethanol makes pure content reach 40～80% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.04～1.40 in the time of 50～90 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously adds the one or any combination in polyethylene glycol 6000, Macrogol 4000, the polyethylene glycol 1500, and heating dissolves, and adopts that to drip speed be 15～90/min, splashes in the condensed fluid, promptly gets drop pill.

The preparation method of preferred drop pill of the present invention comprises the steps:

A. 53.54～86.70 parts of extracting honeysuckles, 53.54～86.70 parts of Radix Scutellariaes, 53.54～86.70 parts of Herba Schizonepetae, 53.54～86.70 parts of Fructus Gardeniaes, 53.54～86.70 parts of Fructus Forsythiaes, 53.54～86.70 parts of Radix Scrophulariaes, 33.57～51.55 parts of Bombyx Batryticatus, 86.27～129.81 parts of Radix Rehmanniae, 17.54～26.70 parts of Rhizoma Belamcandae, 33.57～51.55 parts of Radix Platycodoniss, 33.57～51.55 parts of Herba Menthaes, 33.57～51.55 parts of Radix Saposhnikoviaes, 33.57～51.55 parts of Periostracum Cicadaes, 17.54～26.70 parts in Radix Glycyrrhizae are standby;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 50～80% ethanol extractions 2～4 times, and each 0.5～3.5 hour, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2～4 times, each 0.5～3.5 hour, collecting decoction, filter, filtrate is concentrated into that relative density is 1.05～1.15 in the time of 55～85 ℃, adding ethanol makes pure content reach 50～70% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.06～1.35 in the time of 55～85 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously adds the one or any combination in polyethylene glycol 6000, the Macrogol 4000, and heating dissolves, and adopts that to drip speed be 20～80/min, splashes in the condensed fluid, promptly gets drop pill.

Further the preparation method of preferred drop pill of the present invention comprises the steps:

A. 69～75 parts of extracting honeysuckles, 69～75 parts of Radix Scutellariaes, 69～75 parts of Herba Schizonepetae, 69～75 parts of Fructus Gardeniaes, 69～75 parts of Fructus Forsythiaes, 69～75 parts of Radix Scrophulariaes, 40～47 parts of Bombyx Batryticatus, 100～115 parts of Radix Rehmanniae, 20～25 parts of Rhizoma Belamcandae, 40～47 parts of Radix Platycodoniss, 40～47 parts of Herba Menthaes, 40～47 parts of Periostracum Cicadaes, 40～47 parts of Radix Saposhnikoviaes, 20～24 parts in Radix Glycyrrhizae are standby;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 55～75% ethanol extractions 2～3 times, and each 1～3 hour, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2～3 times, each 1～3 hour, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 60～80 ℃, adding ethanol makes pure content reach 55～65% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.10～1.30 in the time of 60～80 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously, the polyethylene glycol 6000 that adds 1～20 times of amount of medicated powder: Macrogol 4000=1～5: 1～4 mixture, heating dissolves, adopting a speed is 25～75/min, splash into liquid Paraffin, or methyl-silicone oil or methyl-silicone oil: liquid Paraffin=1～4: in 1～3 the condensed fluid, promptly get drop pill.

The preparation method of best drop pill of the present invention comprises the steps:

A. 72 parts of extracting honeysuckles, 72 parts of Radix Scutellariaes, 72 parts of Herba Schizonepetae, 72 parts of Fructus Gardeniaes, 72 parts of Fructus Forsythiaes, 72 parts of Radix Scrophulariaes, 43 parts of Bombyx Batryticatus, 108 parts of Radix Rehmanniae, 22 parts of Rhizoma Belamcandae, 43 parts of Radix Platycodoniss, 43 parts of Herba Menthaes, 43 parts of Periostracum Cicadaes, 43 parts of Radix Saposhnikoviaes, 22 parts in Radix Glycyrrhizae are standby;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 65% ethanol extraction 2 times, and each 2 hours, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, 2 hours for the first time, 1 hour for the second time, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 70 ℃, adding ethanol makes pure content reach 60% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.16～1.20 in the time of 70 ℃, adds the Radix Scutellariae ethanol extract, concentrates, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously, the polyethylene glycol 6000 that adds 4～6 times of amounts of medicated powder: Macrogol 4000=2～4: 2～3 mixture, heating dissolves, adopting a speed is 35～65/min, splash into condensed fluid (liquid Paraffin, or methyl-silicone oil: liquid Paraffin=3: 1), promptly get drop pill.

Capsule of the present invention can adopt following preparation method, comprises the steps:

(a). 36～145 parts of extracting honeysuckles, 36～145 parts of Radix Scutellariaes, 36～145 parts of Herba Schizonepetae, 36～145 parts of Fructus Gardeniaes, 36～145 parts of Fructus Forsythiaes, 36～145 parts of Radix Scrophulariaes, 22～85 parts of Bombyx Batryticatus, 55～215 parts of Radix Rehmanniae, 11～45 parts of Rhizoma Belamcandae, 22～85 parts of Radix Platycodoniss, 22～85 parts of Herba Menthaes, 22～85 parts of Periostracum Cicadaes, 22～85 parts of Radix Saposhnikoviaes, 11～45 parts in Radix Glycyrrhizae are standby;

(b). above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 45～85% ethanol extractions 1～4 time, and each 0.5～4 hour, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 1～4 time, each 0.5～4 hour, collecting decoction, filter, filtrate is concentrated into that relative density is 1.03～1.25 in the time of 50～90 ℃, adding ethanol makes pure content reach 40～80% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.04～1.40 in the time of 50～90 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

(c). the powder of getting it filled sprays into volatile oil; Mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.The preparation method of preferred capsule of the present invention comprises the steps:

(a). 53.54～86.70 parts of extracting honeysuckles, 53.54～86.70 parts of Radix Scutellariaes, 53.54～86.70 parts of Herba Schizonepetae, 53.54～86.70 parts of Fructus Gardeniaes, 53.54～86.70 parts of Fructus Forsythiaes, 53.54～86.70 parts of Radix Scrophulariaes, 33.57～51.55 parts of Bombyx Batryticatus, 86.27～129.81 parts of Radix Rehmanniae, 17.54～26.70 parts of Rhizoma Belamcandae, 33.57～51.55 parts of Radix Platycodoniss, 33.57～51.55 parts of Herba Menthaes, 33.57～51.55 parts of Radix Saposhnikoviaes, 33.57～51.55 parts of Periostracum Cicadaes, 17.54～26.70 parts in Radix Glycyrrhizae are standby;

(b). above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 55～75% ethanol extractions 2～3 times, and each 1～3 hour, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2～3 times, each 1～3 hour, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 60～80 ℃, adding ethanol makes pure content reach 55～65% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.10～1.30 in the time of 60～80 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

(c). the powder of getting it filled adds the conventional adjuvant of capsule, granulates according to the conventional preparation method of capsule, sprays into volatile oil; Mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

The preparation method of best capsule of the present invention comprises the steps:

(a). 72 parts of extracting honeysuckles, 72 parts of Radix Scutellariaes, 72 parts of Herba Schizonepetae, 72 parts of Fructus Gardeniaes, 72 parts of Fructus Forsythiaes, 72 parts of Radix Scrophulariaes, 43 parts of Bombyx Batryticatus, 108 parts of Radix Rehmanniae, 22 parts of Rhizoma Belamcandae, 43 parts of Radix Platycodoniss, 43 parts of Herba Menthaes, 43 parts of Periostracum Cicadaes, 43 parts of Radix Saposhnikoviaes, 22 parts in Radix Glycyrrhizae are standby;

(b). above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 65% ethanol extraction 2 times, and each 2 hours, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, 2 hours for the first time, 1 hour for the second time, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 70 ℃, adding ethanol makes pure content reach 60% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.16～1.20 in the time of 70 ℃, adds the Radix Scutellariae ethanol extract, concentrates, drying must get medicated powder;

(c). the powder of getting it filled, the combination of one or more of adjuvants such as adding cane sugar powder, lactose, starch, dextrin, lactose, PVP, carboxymethyl starch sodium, mix homogeneously, adding concentration is 10～70% alcohol granulations, the consumption capsule is 5%～50% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Mix homogeneously in the capsule for medicine of packing into, promptly gets colloid.

More than form when producing and to increase or to reduce according to corresponding ratio, as large-scale production can be unit with kilogram or with the ton, small-scale production can be unit with the gram also, and weight can increase or reduce, but the crude drug material weight proportion constant rate between each composition.

The specific embodiment

In order to understand the present invention better, below by observing aforementioned pharmaceutical compositions, the effect of medicine of the present invention is described to eliminating evil effect (antiviral, antibacterium effect), heat clearing away effect, antiinflammatory action, to the effect of Immune Effects, analgesic activity and animal acute toxicity test, long-term toxicity test for animals.Below used medicine, below will obtain medicine according to embodiment 10 and be called for short this bright medicine for the ease of narration according to the preparation of embodiment 10 methods in the test.

One. eliminating evil effect (antiviral, antibacterium effect)

1. the external resisiting influenza virus experimental study of medicine of the present invention

Result of the test shows: medicine of the present invention has blocking virus breeding effect again to influenza virus A 3 types, B-mode existing direct killing effect.Its direct killing effect minimal effective concentration is 0.1g crude drug/ml, and its blocking-up breeding effect minimal effective concentration is 0.5g crude drug/ml.

2. medicine of the present invention is to the inhibitory action of influenza virus in the mice body

Result of the test shows: medicine of the present invention can significantly alleviate the pneumonia degree of influenza virus induced mice, and can suppress the proliferative amount of influenza virus in the Mus lung by specificity.Illustrate that medicine popularity flu of the present invention has certain preventive effect.

3. the antibacterial action of medicine of the present invention

Result of the test shows: medicine of the present invention has the obvious suppression effect to the respiratory tract common pathogen as: golden staphylococci, table Portugal, lung bar, the two balls of lung, intestinal ball, first chain, second chain etc., the antimicrobial spectrum broad, especially higher to suppression ratio such as the bigger pathogenic bacterium of toxicity such as golden Portugal, first chain, second chains, compare with contrast medicine YINQIAO JIEDU PIAN, antimicrobial spectrum and antibacterial strength are approximate.

4. medicine of the present invention is to the protective effect of mice lethal infection of staphylococcus aureus death

Result of the test shows: medicine of the present invention has therapeutical effect preferably to the infection of staphylococcus aureus patient.

Two. the heat clearing away effect

By observing the influence of medicine of the present invention to typhoid fever, paratyphoid fever, second triple vaccine pyrogenicity rabbit body temperature; Influence to yeast pyrogenicity rat temperature: to 2, the influence of 2, 4-dinitrophenol pyrogenicity rat temperature, find that medicine of the present invention has definite refrigeration function.

Three. antiinflammatory action

By observe medicine of the present invention to histamine cause influence that vascular permeability increases, to the influence of Oleum Tiglii induced mice ear inflammation, to the influence research of rat Ovum Gallus domesticus album arthroncus, the result shows that medicine of the present invention has tangible antiinflammatory action.

Four. to Immune Effects

1. medicine of the present invention is to the influence of non-specific immunity

By experimental observation, find that medicine of the present invention to normal mouse with because of the infective virus immunologic function all arrives the mice that suppresses, all can improve its specific immune function, and reticuloendothelial system phagocytic increased functionality and used dosage positive correlation once.

2. medicine of the present invention is to normal and modeling mice week blood ANAE positive lymphocyte percentage rate influence

Result of the test shows: medicine pair cell of the present invention immunity has regulating action.

Five. analgesic activity

Show that with the test data result who is obtained the abdominal cavity pain that medicine Dichlorodiphenyl Acetate of the present invention causes has good analgesic activity by experimental observation.

Six. animal acute toxicity test

Result of the test shows: press the maximum tolerance determination test requirements document, medicine of the present invention with gastric infusion in the 2g crude drug, each administration volume 0.4ml/10g one day three times after, except that seeing that one crosses the property loose stool, do not see other toxic reaction.TDD reaches 240g crude drug/kg, and 300 times of the clinical application amount that is equivalent to be grown up still do not cause death, show that this product acute toxicity is very little, and oral safety can clinical practice.

Seven, long-term toxicity test for animals

Result of the test shows: medicine of the present invention is when low (22g crude drug/kg, quite with 28 times of the clinical consumptions of adult), high (50g crude drug/kg, quite and 63 times of the clinical consumptions of being grown up) two dosage levels, through gastric infusion after 16 days, the pathology microscopy of general state, body weight, diet, hemogram, hepatic and renal function and the important organ of animal is not all found obvious drug toxicity influence.Show that this product toxicity is very low, clinical medicine dose is safe and reliable.

Further set forth the preparation method of medicine of the present invention by the following examples.

EXAMPLE l

A. get prescription one: Flos Lonicerae 36g, Radix Scutellariae 36g, Herba Schizonepetae 36g, Fructus Gardeniae 36g, Fructus Forsythiae 36g, Radix Scrophulariae 36g, Bombyx Batryticatus 22g, Radix Rehmanniae 55g, Rhizoma Belamcandae 11g, Radix Platycodonis 22g, Herba Menthae 22g, Periostracum Cicadae 22g, Radix Saposhnikoviae 22g, Radix Glycyrrhizae 11g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 12 times of amount alcohol refluxs 3 times, each 3 hours, concentration of ethanol was 90%, reclaimed ethanol, was concentrated into relative density 1.03～1.35 in the time of 70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 8 times of water gagings, soak after 0.5 hour, adopted steam distillation l hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 3 times, decoct 3 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.30 in the time of 80 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 90 ℃, drying gets medicated powder I;

C. get it filled powder I, medicated powder II add dextrin, mix homogeneously, and adding concentration is 80% alcohol granulation, consumption is 80% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously, tabletting promptly gets tablet.

Embodiment 2

A. get prescription two: Flos Lonicerae 145g, Radix Scutellariae 145g, Herba Schizonepetae 145g, Fructus Gardeniae 145g, Fructus Forsythiae 145g, Radix Scrophulariae 145g, Bombyx Batryticatus 85g, Radix Rehmanniae 215g, Rhizoma Belamcandae 45g, Radix Platycodonis 85g, Herba Menthae 85g, Periostracum Cicadae 85g, Radix Saposhnikoviae 85g, Radix Glycyrrhizae 45g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 1 times of amount alcohol reflux 1 time, extracted 1 hour, concentration of ethanol is 30%, reclaims ethanol, is concentrated into relative density 1.03～1.35 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 1 times of water gaging, soak after 0.5 hour, adopted steam distillation 8 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 1 time, decoct 0.5 hour, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.30 in the time of 50 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 10%, left standstill 4 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 50 ℃, drying gets medicated powder I;

C. get it filled powder I, medicated powder II add starch, lactose, mix homogeneously, and adding concentration is 5% alcohol granulation, consumption is 2% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add silica gel, mix homogeneously, tabletting, coating promptly gets tablet.

Embodiment 3

A. get prescription three: Flos Lonicerae 145g, Radix Scutellariae 45g, Herba Schizonepetae 36g, Fructus Gardeniae 36g, Fructus Forsythiae 145g, Radix Scrophulariae 36g, Bombyx Batryticatus 22g, Radix Rehmanniae 55g, Rhizoma Belamcandae 11g, Radix Platycodonis 85g, Herba Menthae 85g, Periostracum Cicadae 22g, Radix Saposhnikoviae 85g, Radix Glycyrrhizae 45g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol refluxs 3 times, 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.03～1.35 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 4.5 times of water gagings, soak after 3 hours, adopted steam distillation 5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 2 times, and 2 hours for the first time, 1 hour for the second time, collecting decoction filtered, and filtrate is concentrated into relative density 1.02～1.30 in the time of 60 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 25%, left standstill 32 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 60 ℃, drying gets medicated powder I;

C. get it filled powder I, medicated powder II add PVP, carboxymethyl starch sodium, mix homogeneously, and adding concentration is 75% alcohol granulation, consumption is 60% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, Polyethylene Glycol, mix homogeneously, tabletting, coating or coating not promptly get tablet.

Embodiment 4

A. get prescription four: Flos Lonicerae 86.70g, Radix Scutellariae 86.70g, Herba Schizonepetae 86.70g, Fructus Gardeniae (stir-fry) 86.70g, Fructus Forsythiae 86.70g, Radix Scrophulariae 86.70g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 51.55g, Radix Rehmanniae 129.81g, Rhizoma Belamcandae 26.70g, Radix Platycodonis 51.55g, Herba Menthae 51.55g, Radix Saposhnikoviae 51.55g, Periostracum Cicadae 51.55g, Radix Glycyrrhizae 26.70g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol reflux secondaries, each 3 hours, concentration of ethanol was 80%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 65 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 7 times of water gagings, soak after 4 hours, adopted steam distillation 7 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 40 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 80 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add PVP, mix homogeneously, and adding concentration is 75% alcohol granulation, consumption is 60% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add Polyethylene Glycol, mix homogeneously, tabletting promptly gets tablet.

Embodiment 5

A. get prescription five: Flos Lonicerae 53.54g, Radix Scutellariae 53.54g, Herba Schizonepetae 53.54g, Fructus Gardeniae (stir-fry) 53.54g, Fructus Forsythiae 53.54g, Radix Scrophulariae 53.54g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 33.57g, Radix Rehmanniae 86.27g, Rhizoma Belamcandae 17.54g, Radix Platycodonis 33.57g, Herba Menthae 33.57g, Radix Saposhnikoviae 33.57g, Periostracum Cicadae 33.57g, Radix Glycyrrhizae 17.54g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol reflux secondaries, each 1 hour, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 1 times of water gaging, soak after 1 hour, adopted steam distillation 1 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 60 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 15%, left standstill 6～40 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 60 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add starch, mix homogeneously, and adding concentration is 10% alcohol granulation, consumption is 60% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously, tabletting, coating or coating not promptly get tablet.

Embodiment 6

A. get prescription six: Flos Lonicerae 86.70g, Radix Scutellariae 53.54g, Herba Schizonepetae 86.70g, Fructus Gardeniae (stir-fry) 53.54g, Fructus Forsythiae 86.70g, Radix Scrophulariae 53.54g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 51.55g, Radix Rehmanniae 86.27g, Rhizoma Belamcandae 26.70g, Radix Platycodonis 33.57g, Herba Menthae 51.55g, Radix Saposhnikoviae 33.57g, Periostracum Cicadae 51.55g, Radix Glycyrrhizae 17.54g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, 2 hours for the first time, 1 hour for the second time, concentration of ethanol was 40%～80%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～65 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 3 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1.5 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 35%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add dextrin, PVP, carboxymethyl starch sodium, mix homogeneously, and adding concentration is 20% alcohol granulation, consumption is 40% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add silica gel, mix homogeneously, tabletting, coating or coating not promptly get tablet.

Embodiment 7

A. get prescription seven: Flos Lonicerae 75g, Radix Scutellariae 75g, Herba Schizonepetae 75g, Fructus Gardeniae 75g, Fructus Forsythiae 75g, Radix Scrophulariae 75g, Bombyx Batryticatus 47g, Radix Rehmanniae 115g, Rhizoma Belamcandae 25g, Radix Platycodonis 47g, Herba Menthae 47g, Periostracum Cicadae 47g, Radix Saposhnikoviae 47g, Radix Glycyrrhizae 24g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 8 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 80%, reclaimed ethanol, was concentrated into relative density 1.10～1.25 in the time of 60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 4 times of water gagings, soak after 3 hours, adopted steam distillation 6 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add starch and PVP, mix homogeneously, and adding concentration is 70% alcohol granulation, consumption is 50% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add Polyethylene Glycol, mix homogeneously, tabletting, coating promptly gets tablet.

Embodiment 8

A. get prescription eight: Flos Lonicerae 69g, Radix Scutellariae 69g, Herba Schizonepetae 69g, Fructus Gardeniae 69g, Fructus Forsythiae 69g, Radix Scrophulariae 69g, Bombyx Batryticatus 40g, Radix Rehmanniae 100g, Rhizoma Belamcandae 20g, Radix Platycodonis 40g, Herba Menthae 40g, Periostracum Cicadae 40g, Radix Saposhnikoviae 40g, Radix Glycyrrhizae 20g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.10～1.25 in the time of 55 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 1 times of water gaging, soak after 1 hour, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 60 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 80 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add dextrin, mix homogeneously, and adding concentration is 10% alcohol granulation, consumption is 15% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add Polyethylene Glycol, mix homogeneously, tabletting, coating or coating not promptly get tablet.

Embodiment 9

A. get prescription nine: Flos Lonicerae 75g, Radix Scutellariae 69g, Herba Schizonepetae 75g, Fructus Gardeniae 69g, Fructus Forsythiae 75g, Radix Scrophulariae 75g, Bombyx Batryticatus 40, Radix Rehmanniae 115g, Rhizoma Belamcandae 25g, Radix Platycodonis 40g, Herba Menthae 40g, Periostracum Cicadae 40g, Radix Saposhnikoviae 47g, Radix Glycyrrhizae 20g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 1 hour, concentration of ethanol was 55%, reclaimed ethanol, was concentrated into relative density 1.10～1.25 in the time of 55～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 3.5 times of water gagings, soak after 2.5 hours, adopted steam distillation 4.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2.5 hours for the first time, decoct 1.5 hours for the second time, collecting decoction, filter, filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 40%, left standstill 18 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add the combination of an amount of dextrin, lactose, mix homogeneously, and adding concentration is 40% alcohol granulation, consumption is 25% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously, tabletting, coating promptly gets tablet.

Embodiment 10

A. get prescription ten: Flos Lonicerae 72g, Radix Scutellariae 72g, Herba Schizonepetae 72g, Fructus Gardeniae 72g, Fructus Forsythiae 72g, Radix Scrophulariae 72g, Bombyx Batryticatus 43g, Radix Rehmanniae 108g, Rhizoma Belamcandae 22g, Radix Platycodonis 43g, Herba Menthae 43g, Periostracum Cicadae 43g, Radix Saposhnikoviae 43g, Radix Glycyrrhizae 22g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add starch, and amount of starch is medicated powder I and medicated powder II weight 2 times, mix homogeneously, and adding concentration is 50% alcohol granulation, consumption is 20% of medicated powder and a starch consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously, tabletting, coating promptly gets tablet.

Embodiment 11

A. get prescription, it is standby with embodiment 7 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 9 times of amount alcohol refluxs 3 times, 1 hour for the first time, 2 hours for the second time, 3 hours for the third time, concentration of ethanol was 50～60%, reclaimed ethanol, be concentrated in the time of 45 ℃～70 ℃, relative density 1.02～1.25, drying, medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 7.5 times of water gagings, soak after 1.5 hours, adopted steam distillation 2.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 2 times, decoct 1.5 hours at every turn, and collecting decoction filters, and filtrate is concentrated in the time of 50～80 ℃, relative density 1.02～1.30, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 35%, left standstill 40 hours, filter; 4. reclaim ethanol, be concentrated in the time of 50～80 ℃, relative density 1.05～1.45, medicated powder II;

C. get it filled powder I, medicated powder II add starch, dextrin, the lactose of equivalent, mix homogeneously, and adding concentration is 80% alcohol granulation, consumption is 6% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add silica gel, mix homogeneously, tabletting promptly gets tablet.

Embodiment 12

A. get prescription, it is standby with embodiment 9 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol refluxs 1 time, extracted 3 hours, concentration of ethanol is 90%, reclaims ethanol, is concentrated into relative density 1.12～1.25 in the time of 65 ℃～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 3.5 times of water gagings, soak after 5 hours, adopted steam distillation 1.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 3 times, decoct 1.5 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.12～1.20 in the time of 60～80 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 55%, left standstill 48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.15～1.35 in the time of 50～80 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add dextrin, lactose, PVP, mix homogeneously, and adding concentration is 80% alcohol granulation, consumption is 80% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add one or several combinations in magnesium stearate, silica gel, the Polyethylene Glycol, mix homogeneously, tabletting, coating promptly gets tablet.

Embodiment 13

A. get prescription, it is standby with embodiment 3 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2.5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 85%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 4 times of water gagings, soak after 0.5 hour, adopted steam distillation 6 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 1 hour for the first time, decoct 2 hours for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.14～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of starch, lactose, carboxymethyl starch sodium, mix homogeneously, and adding concentration is 70% alcohol granulation, consumption is 50% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, silica gel combination, mix homogeneously, tabletting, coating promptly gets tablet.

Embodiment 14

A. get prescription, it is standby with embodiment 5 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 6.5 times of amount alcohol reflux secondaries, each 0.5 hour, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.05～1.08 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 3 times of water gagings, soak after 2 hours, adopted steam distillation 4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2.5 hours for the first time, decocted 1.5 hours for the second time, collecting decoction filters, filtrate is concentrated into relative density 1.06～1.15 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 65%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add carboxymethyl starch sodium, mix homogeneously, and adding concentration is 70% alcohol granulation, consumption is 5% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously, tabletting, coating does not promptly get tablet.

Embodiment 15

A. extracting honeysuckle 145g, Radix Scutellariae 45g, Herba Schizonepetae 36g, Fructus Gardeniae 36g, Fructus Forsythiae 145g, Radix Scrophulariae 36g, Bombyx Batryticatus 22g, Radix Rehmanniae 55g, Rhizoma Belamcandae 11g, Radix Platycodonis 85g, Herba Menthae 85g, Periostracum Cicadae 22g, Radix Saposhnikoviae 85g, Radix Glycyrrhizae 45g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 1.5 times of amount alcohol reflux secondaries, each 1.5 hours, concentration of ethanol was 45%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2 times of water gagings, soak after 2 hours, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 2 hours for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 22 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of PVP, carboxymethyl starch sodium, mix homogeneously, and adding concentration is 20% alcohol granulation, consumption is 20% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add Polyethylene Glycol, mix homogeneously, tabletting, coating or coating not promptly get tablet.

Embodiment 16

A. get prescription, it is standby with embodiment 1 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 9 times of amount alcohol refluxs 3 times, each 1.5 hours, concentration of ethanol was 95%, reclaimed ethanol, was concentrated into relative density 1.01～1.35 in the time of 85 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 5 times of water gagings, soak after 4 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 2 times, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.01～1.35 in the time of 85 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 32 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.01～1.45 in the time of 90 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add tablet adjuvant commonly used and granulate; With particle drying, spray into volatile oil; Add tablet adjuvant commonly used, mix homogeneously, tabletting promptly gets tablet.

Embodiment 17

A. get prescription, it is standby with embodiment 3 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol refluxs 2 times, each 2 hours, concentration of ethanol was 30%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 4 times of water gagings, soak after 2 hours, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 2 times, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.25 in the time of 50～55 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 35%, left standstill 18 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.04～1.45 in the time of 50～90 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add tablet adjuvant commonly used and granulate; With particle drying, spray into volatile oil; Add tablet adjuvant commonly used, mix homogeneously, tabletting, coating or coating not promptly get tablet.

Embodiment 18

A. get prescription, it is standby with embodiment 4 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 1.5 hours, concentration of ethanol was 60%, reclaimed ethanol, was concentrated into relative density 1.02～1.30 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 1 times of water gaging, soak after 1 hour, adopted steam distillation 1 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.20 in the time of 60～80 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add tablet adjuvant commonly used and granulate; With particle drying, spray into volatile oil; Add tablet adjuvant commonly used, mix homogeneously, tabletting, coating or coating not promptly get tablet.

Embodiment 19

A. get prescription, it is standby with embodiment 5 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 6 times of amount alcohol reflux secondaries, each 1.5 hours, concentration of ethanol was 90%, reclaimed ethanol, was concentrated into relative density 1.02～1.20 in the time of 45～50 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 3 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, and 2 hours for the first time, 1 hour for the second time, collecting decoction filtered, and filtrate is concentrated into relative density 1.05～1.20 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 16 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.20 in the time of 60～70 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add starch, and amount of starch is medicated powder I and medicated powder II weight 0.4 times, mix homogeneously, and adding concentration is 70% alcohol granulation, consumption is 50% of medicated powder and a starch consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously, tabletting, coating promptly gets tablet.

Embodiment 20

A. get prescription, it is standby with embodiment 6 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, 2 hours for the first time, 1 hour for the second time, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.06～1.25 in the time of 55～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 2 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, and 2 hours for the first time, 0.5 hour for the second time, collecting decoction filtered, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 12 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.30 in the time of 70～80 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add starch, and amount of starch is medicated powder I and medicated powder II weight 1 times, mix homogeneously, and adding concentration is 50% alcohol granulation, consumption is 20% of medicated powder and a starch consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously, tabletting, coating promptly gets tablet.

Embodiment 21

A. get prescription, it is standby with embodiment 6 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 60%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 1 hour, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add dextrin, mix homogeneously, and adding concentration is 10% alcohol granulation, consumption is 40% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add silica gel, mix homogeneously, tabletting, coating or coating not promptly get tablet.

Embodiment 22

A. get prescription, it is standby with embodiment 8 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 2 hours, adopted steam distillation 4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 70%, left standstill 18 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add starch, and amount of starch is medicated powder I and medicated powder II weight 1.5 times, mix homogeneously, and adding concentration is 30% alcohol granulation, consumption is 30% of medicated powder and a starch consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously, tabletting, coating promptly gets tablet.

Embodiment 23

A. get prescription, it is standby with embodiment 9 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5.5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 55%, reclaimed ethanol, was concentrated into relative density 1.05～1.15 in the time of 55～65 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2.5 times of water gagings, soak after 1.5 hours, adopted steam distillation 3.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1.5 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.11 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 40%, left standstill 40 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.15 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add starch, and amount of starch is medicated powder I and medicated powder II weight 1.2 times, mix homogeneously, and adding concentration is 60% alcohol granulation, consumption is 15% of medicated powder and a starch consumption; With particle drying. spray into volatile oil; Add magnesium stearate, mix homogeneously, tabletting, coating promptly gets tablet.

Embodiment 24

A. extracting honeysuckle 36g, Radix Scutellariae 36g, Herba Schizonepetae 36g, Fructus Gardeniae 36g, Fructus Forsythiae 36g, Radix Scrophulariae 36g, Bombyx Batryticatus 22g, Radix Rehmanniae 55g, Rhizoma Belamcandae 11g, Radix Platycodonis 22g, Herba Menthae 22g, Periostracum Cicadae 22g, Radix Saposhnikoviae 22g, Radix Glycyrrhizae 11g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 12 times of amount alcohol refluxs 3 times, each 4 hours, concentration of ethanol was 90%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 12 times of water gagings, soak after 5 hours, adopted steam distillation 8 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 3 times, decoct 3 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.30 in the time of 80 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.15 in the time of 85 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds polyethylene glycol 6000, and heating dissolves, and adopts that to drip speed be 90/min, splashes in the condensed fluid, promptly gets drop pill.

Embodiment 25

A. extracting honeysuckle 145g, Radix Scutellariae 145g, Herba Schizonepetae 145g, Fructus Gardeniae 145g, Fructus Forsythiae 145g, Radix Scrophulariae 145g, Bombyx Batryticatus 85g, Radix Rehmanniae 215g, Rhizoma Belamcandae 45g, Radix Platycodonis 85g, Herba Menthae 85g, Periostracum Cicadae 85g, Radix Saposhnikoviae 85g, Radix Glycyrrhizae 45g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 1 times of amount alcohol reflux 3 times, each 0.5 hour, concentration of ethanol was 30%, reclaimed ethanol, was concentrated into relative density 1.12～1.25 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 1 times of water gaging, soak after 0.2 hour, adopted steam distillation 1 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 1 time, decoct 0.2 hour, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.30 in the time of 30 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 10%, left standstill 4 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 40 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds Macrogol 4000, and heating dissolves, and adopts that to drip speed be 80/min, splashes in the condensed fluid, promptly gets drop pill.

Embodiment 26

A. extracting honeysuckle 145g, Radix Scutellariae 45g, Herba Schizonepetae 36g, Fructus Gardeniae 36g, Fructus Forsythiae 145g, Radix Scrophulariae 36g, Bombyx Batryticatus 22g, Radix Rehmanniae 55g, Rhizoma Belamcandae 11g, Radix Platycodonis 85g, Herba Menthae 85g, Periostracum Cicadae 22g, Radix Saposhnikoviae 85g, Radix Glycyrrhizae 45g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol refluxs 3 times, 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, concentration of ethanol was 80%, reclaimed ethanol, was concentrated into relative density 1.05～1.20 in the time of 65 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 10 times of water gagings, soak after 4 hours, adopted steam distillation 7 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 3 times, decoct 2.5 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.05～1.25 in the time of 60～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 75%, left standstill 36 hours, filter; 4. reclaim ethanol, be concentrated into, get medicated powder II 70～80 ℃ of timing relative densities 1.05～1.45;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds polyethylene glycol 1500, and heating dissolves, and adopts that to drip speed be 85/min, splashes in the condensed fluid, promptly gets drop pill.

Embodiment 27

A. extracting honeysuckle 86.70g, Radix Scutellariae 86.70g, Herba Schizonepetae 86.70g, Fructus Gardeniae (stir-fry) 86.70g, Fructus Forsythiae 86.70g, Radix Scrophulariae 86.70g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 51.55g, Radix Rehmanniae 129.81g, Rhizoma Belamcandae 26.70g, Radix Platycodonis 51.55g, Herba Menthae 51.55g, Radix Saposhnikoviae 51.55g, Periostracum Cicadae 51.55g, Radix Glycyrrhizae 26.70g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol refluxs 1 time, extracted 3 hours, concentration of ethanol is 40%, reclaims ethanol, is concentrated into relative density 1.05～1.20 in the time of 50 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2 times of water gagings, soak after 0.5 hour, adopted steam distillation 1.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 1 time, decoct 2.5 hours, and collecting decoction filters, and filtrate is concentrated into relative density 1.05～1.25 in the time of 40～50 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into, get medicated powder II 50～60 ℃ of timing relative densities 1.05～1.45;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the mixture of polyethylene glycol 6000, polyethylene glycol 1500, the amount that adds is a polyethylene glycol 6000: polyethylene glycol 1500 is 3: 1, and heating dissolves, and adopting a speed is 20～80/min, splash in the condensed fluid, promptly get drop pill.

Embodiment 28

A. extracting honeysuckle 53.54g, Radix Scutellariae 53.54g, Herba Schizonepetae 53.54g, Fructus Gardeniae (stir-fry) 53.54g, Fructus Forsythiae 53.54g, Radix Scrophulariae 53.54g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 33.57g, Radix Rehmanniae 86.27g, Rhizoma Belamcandae 17.54g, Radix Platycodonis 33.57g, Herba Menthae 33.57g, Radix Saposhnikoviae 33.57g, Periostracum Cicadae 33.57g, Radix Glycyrrhizae 17.54g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 8 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 3 hours, adopted steam distillation 6 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 12 hours, filter; 4. reclaim ethanol, be concentrated into, get medicated powder II 70 ℃ of timing relative densities 1.14～1.25;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously, the polyethylene glycol 6000 that adds 10 times of amounts of medicated powder: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=5: 1, heating dissolves, adopting a speed is 65～75/min, splash into condensed fluid (liquid Paraffin, or methyl-silicone oil: liquid Paraffin=in 4: 1, promptly get drop pill.

Embodiment 29

A. extracting honeysuckle 86.70g, Radix Scutellariae 53.54g, Herba Schizonepetae 86.70g, Fructus Gardeniae (stir-fry) 53.54g, Fructus Forsythiae 86.70g, Radix Scrophulariae 53.54g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 51.55g, Radix Rehmanniae 86.27g, Rhizoma Belamcandae 26.70g, Radix Platycodonis 33.57g, Herba Menthae 51.55g, Radix Saposhnikoviae 33.57g, Periostracum Cicadae 51.55g, Radix Glycyrrhizae 17.54g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 1 times of water gaging, soak after 1 hour, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 1 hour for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 12 hours, filter; 4. reclaim ethanol, be concentrated into, get medicated powder II 70 ℃ of timing relative densities 1.14～1.25;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously, the polyethylene glycol 6000 that adds 4 times of amounts of medicated powder: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=1: 1, heating dissolves, adopting a speed is 45～55/min, splash into methyl-silicone oil: in the condensed fluid of liquid Paraffin=4: 1, promptly get drop pill.

Embodiment 30

A. extracting honeysuckle 75g, Radix Scutellariae 75g, Herba Schizonepetae 75g, Fructus Gardeniae 75g, Fructus Forsythiae 75g, Radix Scrophulariae 75g, Bombyx Batryticatus 47g, Radix Rehmanniae 115g, Rhizoma Belamcandae 25g, Radix Platycodonis 47g, Herba Menthae 47g, Periostracum Cicadae 47g, Radix Saposhnikoviae 47g, Radix Glycyrrhizae 24g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55～57 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 2 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 40%, left standstill 20 hours, filter; 4. reclaim ethanol, be concentrated into, get medicated powder II 70 ℃ of timing relative densities 1.14～1.25;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the polyethylene glycol 6000 of 6 times of amounts of medicated powder: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=2: 3, heating dissolves, adopting a speed is 65～75/min, splashes in the liquid Paraffin, promptly gets drop pill.

Embodiment 31

A. extracting honeysuckle 69g, Radix Scutellariae 69g, Herba Schizonepetae 69g, Fructus Gardeniae 69g, Fructus Forsythiae 69g, Radix Scrophulariae 69g, Bombyx Batryticatus 40g, Radix Rehmanniae 100g, Rhizoma Belamcandae 20g, Radix Platycodonis 40g, Herba Menthae 40g, Periostracum Cicadae 40g, Radix Saposhnikoviae 40g, Radix Glycyrrhizae 20g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 600%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2 times of water gagings, soak after 1.5 hours, adopted steam distillation 2.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into, get medicated powder II 70 ℃ of timing relative densities 1.14～1.25;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the polyethylene glycol 6000 of 4 times of amounts of medicated powder: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=5: 1, heating dissolves, adopting a speed is 55～65/min, splashes in the methyl-silicone oil, promptly gets drop pill.

Embodiment 32

A. extracting honeysuckle 75g, Radix Scutellariae 69g, Herba Schizonepetae 75g, Fructus Gardeniae 69g, Fructus Forsythiae 75g, Radix Scrophulariae 75g, Bombyx Batryticatus 40, Radix Rehmanniae 115g, Rhizoma Belamcandae 25g, Radix Platycodonis 40g, Herba Menthae 40g, Periostracum Cicadae 40g, Radix Saposhnikoviae 47g, Radix Glycyrrhizae 20g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2～8 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 2.5 hours, adopted steam distillation 4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 3 hours for the first time, decoct 2 hours for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 15 hours, filter; 4. reclaim ethanol, be concentrated into, get medicated powder II 70 ℃ of timing relative densities 1.14～1.25;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously, the polyethylene glycol 6000 that adds 5.5 times of amounts of medicated powder: the polyethylene glycol 6000 and the polyethylene glycol 1500 mixture of polyethylene glycol 1500=2: 3, heating dissolves, adopting a speed is 65～70/min, splash into aqueous methyl-silicone oil: in the condensed fluid of liquid Paraffin=1: 1, promptly get drop pill.

Embodiment 33

A. extracting honeysuckle 72g, Radix Scutellariae 72g, Herba Schizonepetae 72g, Fructus Gardeniae 72g, Fructus Forsythiae 72g, Radix Scrophulariae 72g, Bombyx Batryticatus 43g, Radix Rehmanniae 10gg, Rhizoma Belamcandae 22g, Radix Platycodonis 43g, Herba Menthae 43g, Periostracum Cicadae 43g, Radix Saposhnikoviae 43g, Radix Glycyrrhizae 22g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2～8 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 40～80%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 1～4 times of water gaging, soak after 1～3 hour, adopted steam distillation 2～6 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20～80%, left standstill 8～36 hours, filter; 4. reclaim ethanol, be concentrated into, get medicated powder II 70 ℃ of timing relative densities 1.14～1.25;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously, the polyethylene glycol 6000 that adds 1～10 times of amount of medicated powder: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=3: 2, heating dissolves, adopting a speed is 70～75/min, splash into methyl-silicone oil: in the condensing agent of liquid Paraffin=3: 1, promptly get drop pill.

Embodiment 34

A. get prescription, it is standby with embodiment 1 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 9 times of amount alcohol refluxs 3 times, 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, concentration of ethanol was 75%, reclaimed ethanol, was concentrated in the time of 90 ℃, and relative density 1.02～1.25 dryings get medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 4 hours, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 3 hours for the first time 3 times, 2 hours for the second time, 1 hour for the third time, collecting decoction, filter, filtrate is concentrated into relative density 1.02～1.30 in the time of 50～60 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 10%, left standstill 16 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 50～80 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the polyethylene glycol 6000 of 3 times of medicated powder I and medicated powder II amount, and heating dissolves, and adopts that to drip speed be 80～90/min, splashes in the condensed fluid, promptly gets drop pill.

Embodiment 35

A. get prescription, it is standby with embodiment 2 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol refluxs 2 times, 3 hours for the first time, 2 hours for the second time, concentration of ethanol was 75%, reclaimed ethanol, was concentrated into relative density 1.05～1.20 in the time of 50 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 1 hour, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 2 times, decoct 2 hours for the first time, decocted 1 hour for the second time, collecting decoction filters, filtrate is concentrated into relative density 1.07～1.20 in the time of 60～80 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 65%, left standstill 36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.10～1.35 in the time of 50～80 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously, add the 5 times of medicated powder I and the polyethylene glycol 6000 of medicated powder II weight, the mixture of Macrogol 4000, polyethylene glycol 6000: Macrogol 4000 is 4: 1, heating dissolves, adopting a speed is 35～40/min, splashes in the methyl-silicone oil, promptly gets drop pill.

Embodiment 36

A. get prescription, it is standby with embodiment 3 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol refluxs 1 time, extracted 3 hours, concentration of ethanol is 30%, reclaims ethanol, is concentrated into relative density 1.04～1.15 in the time of 45 ℃～50 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 3.5 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 2 times, decoct 2 hours for the first time, decocted 1 hour for the second time, collecting decoction filters, filtrate is concentrated into relative density 1.02～1.30 in the time of 50～80 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.07～1.25 in the time of 50～80 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the Macrogol 4000 of 6 times of medicated powder weight, the mixture of polyethylene glycol 1500, Macrogol 4000: polyethylene glycol 1500 is 3: 2, and heating dissolves, and adopting a speed is 65～70/min, splash in the liquid paraffin, promptly get drop pill.

Embodiment 37

A. get prescription, it is standby with embodiment 4 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 2 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 40%, left standstill 30 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the Macrogol 4000 of 4 times of medicated powder I and medicated powder II amount, and heating dissolves, and adopts that to drip speed be 50～60/min, splashes in 8 ℃ of liquid paraffin, promptly gets drop pill.

Embodiment 38

A. get prescription, it is standby with embodiment 5 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.04～1.12 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 2.5 hours, adopted steam distillation 2.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 40 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 35%, left standstill 12 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously, add the polyethylene glycol 6000 of 4 times of medicated powder weight, the mixture of Macrogol 4000, polyethylene glycol 6000: Macrogol 4000 is 3: 2, heating dissolves, adopting a speed is 40～50/min, splashes in 0～10 ℃ of liquid paraffin, promptly gets drop pill.

Embodiment 39

A. get prescription, it is standby with embodiment 6 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.09～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2.5 times of water gagings, soak after 1 hour, adopted steam distillation 3.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 50 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60～80%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously, add the polyethylene glycol 6000 of 7 times of medicated powder weight, the mixture of Macrogol 4000, polyethylene glycol 6000: Macrogol 4000 is 3: 1, heating dissolves, adopting a speed is 50～80/min, splashes in-10～10 ℃ of methyl-silicone oils, promptly gets drop pill.

Embodiment 40

A. get prescription, it is standby with embodiment 7 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 2 hours, when adopting steam distillation 4, collect volatile oil device preservation in addition, medicinal residues continue to extract: 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decocted 2 hours for the first time, decocted 1 hour for the second time, collecting decoction, filter, filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 70%, left standstill 18 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously, add 4 times of amounts of medicated powder, polyethylene glycol 6000: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=1: 4, heating dissolves, adopting a speed is 75～80/min, splash into methyl-silicone oil: in liquid Paraffin=1: 3 condensed fluid, promptly get drop pill.

Embodiment 41

A. get prescription, it is standby with embodiment 8 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 60%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 2 hours, adopted steam distillation 4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 80 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 50%, left standstill 16 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 (70 ℃ of meters), get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds 3 times of amounts of medicated powder, polyethylene glycol 6000: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=5: 2, heating dissolves, adopting a speed is 50～60/min, splashes in the methyl-silicone oil, promptly gets drop pill.

Embodiment 42

A. get prescription, it is standby with embodiment 9 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 8 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2 times of water gagings, soak after 2 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 60 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 40%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 (70 ℃ of meters), get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds 6 times of amounts of medicated powder, polyethylene glycol 6000: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=3: 2, heating dissolves, adopting a speed is 45～55/min, splashes in 0 ℃ of liquid paraffin, promptly gets drop pill.

Embodiment 43

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 60%, reclaimed ethanol, was concentrated into relative density 1.06～1.12 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2 times of water gagings, soak after 2 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 (70 ℃), puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 30%, left standstill 15 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 (70 ℃ of meters), get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds 5 times of amounts of medicated powder, polyethylene glycol 6000: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=3: 2, heating dissolves, adopting a speed is 65～75/min, splashes in 5 ℃ of liquid paraffin, promptly gets drop pill.

Embodiment 44

A. get prescription, it is standby with embodiment 1 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.12～1.15 (55 ℃～60 ℃ meters), and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.15～1.20 (70 ℃), puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 70%, left standstill 20 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 (70 ℃ of meters), get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds 6 times of amounts of medicated powder, polyethylene glycol 6000: the polyethylene glycol 6000 and the polyethylene glycol 1500 mixture of polyethylene glycol 1500=5: 2, heating dissolves, adopting a speed is 40/min, splashes in 5 ℃ of methyl-silicone oils, promptly gets drop pill.

Embodiment 45

A. extracting honeysuckle 72g, Radix Scutellariae 72g, Herba Schizonepetae 72g, Fructus Gardeniae 72g, Fructus Forsythiae 72g, Radix Scrophulariae 72g, Bombyx Batryticatus 43g, Radix Rehmanniae 108g, Rhizoma Belamcandae 22g, Radix Platycodonis 43g, Herba Menthae 43g, Periostracum Cicadae 43g, Radix Saposhnikoviae 43g, Radix Glycyrrhizae 22g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 57 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 2 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 50%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into, get medicated powder II 70 ℃ of timing relative densities 1.14～1.25;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously, add 5 times of amounts of medicated powder, polyethylene glycol 6000: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=3: 2, heating dissolves, adopting a speed is 70～75/min, splash into methyl-silicone oil: in the condensing agent of liquid Paraffin=3: 1, promptly get drop pill.

Embodiment 46

A. get prescription, it is standby with embodiment 8 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 59 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2 times of water gagings, soak after 1 hour, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 30%, left standstill 20 hours, filter; 4. reclaim ethanol, be concentrated into, get medicated powder II 70 ℃ of timing relative densities 1.14～1.25;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds 4 times of amounts of medicated powder, polyethylene glycol 6000: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=3: 2, heating dissolves, adopting a speed is 70～75/min, splashes in the liquid Paraffin, promptly gets drop pill.

Embodiment 47

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 85% ethanol extraction 4 times, and each 4 hours, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 4 times, each 4 hours, collecting decoction, filter, filtrate is concentrated into that relative density is 1.03～1.25 in the time of 90 ℃, adding ethanol makes pure content reach 80% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.04～1.40 in the time of 90 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously adds polyethylene glycol 6000, and heating dissolves, and adopts that to drip speed be 75～90/min, splashes in-10～10 ℃ of methyl-silicone oils, promptly gets drop pill.

Embodiment 48

A. get prescription, it is standby with embodiment 2 to write out a prescription;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 45% ethanol extraction 1 time, extracts 0.5 hour, reclaims ethanol, adds water and boils in right amount. filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 1 time, extracted 0.5 hour, collecting decoction, filter, filtrate is concentrated into that relative density is 1.03～1.25 in the time of 50 ℃, adding ethanol makes pure content reach 40% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.04～1.40 in the time of 50 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously adds Macrogol 4000, and heating dissolves, and adopts that to drip speed be 65～70/min, splashes in the liquid paraffin, promptly gets drop pill.

Embodiment 49

A. get prescription, it is standby with embodiment 3 to write out a prescription;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 65% ethanol extraction 2 times, and each 3 hours, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, each 3 hours, collecting decoction, filter, filtrate is concentrated into that relative density is 1.03～1.25 in the time of 60 ℃, adding ethanol makes pure content reach 50% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.04～1.40 in the time of 70 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously adds polyethylene glycol 1500, and heating dissolves, and adopts that to drip speed be 65～80/min, splashes in 0～10 ℃, promptly gets drop pill.

Embodiment 50

A. get prescription, it is standby with embodiment 4 to write out a prescription;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 80% ethanol extraction 4 times, and each 3.5 hours, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 4 times, each 3.5 hours, collecting decoction, filter, filtrate is concentrated into that relative density is 1.05～1.15 in the time of 85 ℃, adding ethanol makes pure content reach 70% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.06～1.35 in the time of 85 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously adds polyethylene glycol 6000, and heating dissolves, and adopts that to drip speed be 50～60/min, splashes in the vegetable oil, promptly gets drop pill.

Embodiment 51

A gets prescription, and it is standby with embodiment 5 to write out a prescription;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 50% ethanol extraction 2 times, and each 0.5 hour, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, each 0.5 hour, collecting decoction, filter, filtrate is concentrated into that relative density is 1.05～1.15 in the time of 55 ℃, adding ethanol makes pure content reach 50% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.06～1.35 in the time of 55 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously adds Macrogol 4000, and heating dissolves, and adopts that to drip speed be 70～80/min, splashes in the liquid paraffin, promptly gets drop pill.

Embodiment 52

A. get prescription, it is standby with embodiment 6 to write out a prescription;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 70% ethanol extraction 2 times, and 3.5 hours for the first time, 2 hours for the second time, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, 3.5 hours for the first time, 2 hours for the second time, collecting decoction, filter, filtrate is concentrated into that relative density is 1.05～1.15 in the time of 75 ℃, adding ethanol makes pure content reach 65% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.06～1.35 in the time of 65 ℃, adds the Radix Scutellariae ethanol extract, concentrates, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously adds the polyethylene glycol 6000 of 10 times of amounts of medicated powder: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=1: 4, heating dissolves, adopting a speed is 65～75/min, splashes in the liquid Paraffin, promptly gets drop pill.

Embodiment 53

A. get prescription, it is standby with embodiment 7 to write out a prescription;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 75% ethanol extraction 3 times, and each 3 hours, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 3 times, each 3 hours, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 80 ℃, adding ethanol makes pure content reach 65% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.10～1.30 in the time of 60～80 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously adds the polyethylene glycol 6000 of 8 times of amounts of medicated powder: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=5: 1, heating dissolves, adopting a speed is 60～75/min, splashes in the methyl-silicone oil, promptly gets drop pill.

Embodiment 54

A. get prescription, it is standby with embodiment 8 to write out a prescription;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 60% ethanol extraction 3 times, and 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 3 times, 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 70 ℃, add ethanol and make pure content reach 58% to leave standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.10～1.30 in the time of 75 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously, the polyethylene glycol 6000 that adds 6 times of amounts of medicated powder: the polyethylene glycol 6000 and the polyethylene glycol 1500 mixture of polyethylene glycol 1500=3: 2, heating dissolves, adopting a speed is 25～75/min, splash into aqueous methyl-silicone oil: in the condensed fluid of liquid Paraffin=1: 3, promptly get drop pill.

Embodiment 55

A. get prescription, it is standby with embodiment 9 to write out a prescription;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 65% ethanol extraction 2 times, and 2 hours for the first time, 1 hour for the second time, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, 2 hours for the first time, 1 hour for the second time, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 65 ℃, adding ethanol makes pure content reach 65% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.10～1.30 in the time of 65 ℃, adds the Radix Scutellariae ethanol extract, concentrates, drying must get medicated powder:

C. get it filled powder, volatile oil, mix homogeneously, the polyethylene glycol 6000 that adds 6 times of amounts of medicated powder: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=2: 1, heating dissolves, adopting a speed is 50～75/min, splash into methyl-silicone oil: in the condensed fluid of liquid Paraffin=3: 1, promptly get drop pill.

Embodiment 56

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 65% ethanol extraction 2 times, and each 2 hours, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, 2 hours for the first time, 1 hour for the second time, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 70 ℃, adding ethanol makes pure content reach 60% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.16～1.20 in the time of 70 ℃, adds the Radix Scutellariae ethanol extract, concentrates, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously adds 4～6 times of amounts of medicated powder, polyethylene glycol 6000: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=3: 2, heating dissolves, adopting a speed is 45～75/min, splashes in the liquid Paraffin, promptly gets drop pill.

Embodiment 57

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 75% ethanol extraction 2 times, and each 1 hour, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, 3 hours for the first time, 2 hours for the second time, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 75 ℃, adding ethanol makes pure content reach 60% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.16～1.20 in the time of 75 ℃, adds the Radix Scutellariae ethanol extract, concentrates, drying must get medicated powder;

C. get it filled powder, volatile oil, mix homogeneously, add 5 times of amounts of medicated powder, polyethylene glycol 6000: the polyethylene glycol 6000 and the Macrogol 4000 mixture of Macrogol 4000=3: 2, heating dissolves, adopting a speed is 45～75/min, splash into methyl-silicone oil: in liquid Paraffin=3: 1 condensed fluid, promptly get drop pill.

Embodiment 58

A. get prescription, it is standby with embodiment 1 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 1 times of amount alcohol reflux 1 time, extracted 4 hours, concentration of ethanol is 30%, reclaims ethanol, is concentrated into relative density 1.02～1.25 in the time of 45～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder I: get Radix Scutellariae and add 1 times of amount alcohol reflux 1 time, extracted 1 hour, concentration of ethanol is 95%, reclaims ethanol, is concentrated into relative density 1.01～1.35 in the time of 45～85 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 1 times of water gaging, soak after 0.5 hour, adopted steam distillation 1 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 1 time, extract 3 hours, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.35 in the time of 50～85 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.02～1.45 in the time of 50～90 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the polyethylene glycol 6000 of 25 times of medicated powder amounts, and heating dissolves, and adopts that to drip speed be 80/min, splashes in the condensed fluid, promptly gets drop pill.

Embodiment 59

A. get prescription, it is standby with embodiment 2 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 12 times of amount alcohol refluxs 3 times, each 4 hours, concentration of ethanol was 90%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 45～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder I: get Radix Scutellariae and add 12 times of amount alcohol refluxs 3 times, each 3 hours, concentration of ethanol was 95%, reclaimed ethanol, was concentrated into relative density 1.00～1.35 in the time of 45～85 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 8 times of water gagings, soak after 5 hours, adopted steam distillation 8 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 3 times, decoct 3 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.00～1.35 in the time of 50～85 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 10%, left standstill 4 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.00～1.45 in the time of 50～90 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the Macrogol 4000 of 30 times of medicated powder amounts, and heating dissolves, and adopts that to drip speed be 45～50/min, splashes in the condensed fluid, promptly gets drop pill.

Embodiment 60

A. get prescription, it is standby with embodiment 4 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 90%, reclaimed ethanol, was concentrated into relative density 1.02～1.30 in the time of 45～80 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 7 times of water gagings, soak after 4 hours, adopted steam distillation 7 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.20 in the time of 60～80 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds polyethylene glycol 6000, and heating dissolves, and adopts that to drip speed be 50～60/min, splashes in the condensed fluid, promptly gets drop pill.

Embodiment 61

A. get prescription, it is standby with embodiment 5 to write out a prescription;

B. the extraction of medicated powder I; Get Radix Scutellariae and add 2 times of amount alcohol reflux secondaries, each 1 hour, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.02～1.30 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 1 times of water gaging, soak after 1 hour, adopted steam distillation 1 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.20 in the time of 60～80 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the polyethylene glycol 6000 and the Macrogol 4000 mixture of 10 times of medicated powder amounts, polyethylene glycol 6000: Macrogol 4000 is 2: 1, and heating dissolves, and adopting a speed is 50/min, splash in the condensed fluid, promptly get drop pill.

Embodiment 62

A. get prescription, it is standby with embodiment 6 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, 2 hours for the first time, 1 hour for the second time, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.02～1.30 in the time of 70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 3 hours, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1.5 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 50%, left standstill 16 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.06～1.20 in the time of 60～80 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the Macrogol 4000 of 15 times of amounts of medicated powder, and heating dissolves, and adopts that to drip speed be 30/min, splashes in the condensed fluid, promptly gets drop pill.

Embodiment 63

A. get prescription, it is standby with embodiment 7 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 2 hours, adopted steam distillation 4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the polyethylene glycol 6000 of 30 times of amounts of medicated powder: the mixture of Macrogol 4000=5: 1, heating dissolves, adopt dripping speed is 35～45/min, splashes into methyl-silicone oil: in the condensed fluid of liquid Paraffin=4: 1, promptly get drop pill.

Embodiment 64

A. get prescription, it is standby with embodiment 8 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 60%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 1 hour, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 12 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the polyethylene glycol 6000 of 10 times of amounts of medicated powder: the mixture of Macrogol 4000=1: 1, heating dissolves, adopt dripping speed is 25～75/min, splashes into methyl-silicone oil: in the condensed fluid of liquid Paraffin=1: 3, promptly get drop pill.

Embodiment 65

A. get prescription, it is standby with embodiment 9 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 60%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 55 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3.5 times of water gagings, soak after 1.5 hours, adopted steam distillation 2.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1～2 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 35%, left standstill 16 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the polyethylene glycol 6000 of 15 times of amounts of medicated powder: the mixture of Macrogol 4000=2: 3, heating dissolves, and adopts that to drip speed be 55～65/min, splashes in the liquid Paraffin, promptly gets drop pill.

Embodiment 66

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 6 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 60～70%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3～5 times of water gagings, soak after 1～2 hour, adopted steam distillation 2～4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1～2 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20～80%, left standstill 8～36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the polyethylene glycol 6000 of 5 times of amounts of medicated powder: the mixture of Macrogol 4000=2: 3, heating dissolves, and adopts that to drip speed be 45～50/min, splashes in the methyl-silicone oil, promptly gets drop pill.

Embodiment 67

A. get prescription, it is standby with embodiment 5 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 45%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 40 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 2 hours, adopted steam distillation 4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 30%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously adds the polyethylene glycol 6000 of 6 times of amounts of medicated powder: the mixture of Macrogol 4000=4: 3, heating dissolves, and adopts that to drip speed be 50～60/min, splashes in the liquid Paraffin, promptly gets drop pill.

Embodiment 68

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II, volatile oil, mix homogeneously, add 20 times of amounts of medicated powder, polyethylene glycol 6000: the mixture of Macrogol 4000=3: 2, heating dissolves, adopting a speed is 40/min, splash into liquid Paraffin, or methyl-silicone oil: liquid Paraffin is in 3: 1 the condensed fluid, promptly to get drop pill.

Embodiment 69

A. extracting honeysuckle 36g, Radix Scutellariae 36g, Herba Schizonepetae 36g, Fructus Gardeniae 36g, Fructus Forsythiae 36g, Radix Scrophulariae 36g, Bombyx Batryticatus 22g, Radix Rehmanniae 55g, Rhizoma Belamcandae 11g, Radix Platycodonis 22g, Herba Menthae 22g, Periostracum Cicadae 22g, Radix Saposhnikoviae 22g, Radix Glycyrrhizae 11g;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, and relative density 1.05～1.10 when being concentrated into 60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 2 times of water gagings, soak after 2 hours, adopt steam distillation 3 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and relative density 1.05～1.15 when filtrate was concentrated into 80 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 70%, left standstill 16 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 80 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of starch, dextrin, mix homogeneously, and adding concentration is 50% alcohol granulation, consumption is 30% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add the magnesium stearate mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 70

A. extracting honeysuckle 145g, Radix Scutellariae 145g, Herba Schizonepetae 145g, Fructus Gardeniae 145g, Fructus Forsythiae 145g, Radix Scrophulariae 145g, Bombyx Batryticatus 85g, Radix Rehmanniae 215g, Rhizoma Belamcandae 45g, Radix Platycodonis 85g, Herba Menthae 85g, Periostracum Cicadae 85g, Radix Saposhnikoviae 85g, Radix Glycyrrhizae 45g;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, each 2.5 hours, concentration of ethanol was 35%, reclaimed ethanol, was concentrated into relative density 1.07～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 3.5 times of water gagings, soak after 2.5 hours, adopt steam distillation 3.5 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 45%, left standstill 12 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add carboxymethyl starch sodium, mix homogeneously, and adding concentration is 30% alcohol granulation, consumption is 40% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add silica gel, mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 71

A. extracting honeysuckle 145g, Radix Scutellariae 45g, Herba Schizonepetae 36g, Fructus Gardeniae 36g, Fructus Forsythiae 145g, Radix Scrophulariae 36g, Bombyx Batryticatus 22g, Radix Rehmanniae 55g, Rhizoma Belamcandae 11g, Radix Platycodonis 85g, Herba Menthae 85g, Periostracum Cicadae 22g, Radix Saposhnikoviae 85g, Radix Glycyrrhizae 45g;

B. the extraction of medicated powder I: get Radix Scutellariae and add 6.5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.08～1.10 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 4.5 times of water gagings, soak after 2 hours, adopt steam distillation 2 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 3 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and relative density 1.04～1.20 when filtrate was concentrated into 80 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 75%, left standstill 24 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 80 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of dextrin, PVP, mix homogeneously, and adding concentration is 75% alcohol granulation, consumption is 35% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; The combination that adds magnesium stearate, silica gel, mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 72

A. extracting honeysuckle 86.70g, Radix Scutellariae 86.70g, Herba Schizonepetae 86.70g, Fructus Gardeniae (stir-fry) 86.70g, Fructus Forsythiae 86.70g, Radix Scrophulariae 86.70g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 51.55g, Radix Rehmanniae 129.81g, Rhizoma Belamcandae 26.70g, Radix Platycodonis 51.55g, Herba Menthae 51.55g, Radix Saposhnikoviae 51.55g, Periostracum Cicadae 51.55g, Radix Glycyrrhizae 26.70g;

The extraction of medicated powder I: get Radix Scutellariae and add 5.5 times of amount alcohol reflux secondaries, each 2.5 hours, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.10～1.15 in the time of 55 ℃, and drying gets medicated powder I;

B. the extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 2 times of water gagings, soak after 1 hour, adopt steam distillation 6 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decocted 2 hours for the first time, decocted 1 hour for the second time, collecting decoction filters, filtrate is concentrated into relative density 1.14～1.20 in the time of 50 ℃, put cold: 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 20 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 60 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add carboxymethyl starch sodium, mix homogeneously, and adding concentration is 10% alcohol granulation, consumption is 20% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add Polyethylene Glycol, mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 73

A. extracting honeysuckle 53.54g, Radix Scutellariae 53.54g, Herba Schizonepetae 53.54g, Fructus Gardeniae (stir-fry) 53.54g, Fructus Forsythiae 53.54g, Radix Scrophulariae 53.54g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 33.57g, Radix Rehmanniae 86.27g, Rhizoma Belamcandae 17.54g, Radix Platycodonis 33.57g, Herba Menthae 33.57g, Radix Saposhnikoviae 33.57g, Periostracum Cicadae 33.57g, Radix Glycyrrhizae 17.54g;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 1 hour, concentration of ethanol was 40%, reclaimed ethanol, was concentrated at 55 ℃～60 ℃ meters) relative density 1.02～1.15, drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 4 times of water gagings, soak after 1 hour, adopt steam distillation 2 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 3 hours for the first time, decoct 2 hours for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 (70 ℃), puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 20 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 (70 ℃ of meters), get medicated powder II;

C. get it filled powder I, medicated powder II add starch, mix homogeneously, and adding concentration is 80% alcohol granulation, consumption is 50% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add the magnesium stearate mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 74

A. extracting honeysuckle 86.70g, Radix Scutellariae 53.54g, Herba Schizonepetae 86.70g, Fructus Gardeniae (stir-fry) 53.54g, Fructus Forsythiae 86.70g, Radix Scrophulariae 53.54g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 51.55g, Radix Rehmanniae 86.27g, Rhizoma Belamcandae 26.70g, Radix Platycodonis 33.57g, Herba Menthae 51.55g, Radix Saposhnikoviae 33.57g, Periostracum Cicadae 51.55g, Radix Glycyrrhizae 17.54g;

B. the extraction of medicated powder I: get Radix Scutellariae and add 8 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 80%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 (55 ℃～60 ℃ meters), and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 4 times of water gagings, soak after 3 hours, adopt steam distillation 6 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 (70 ℃), puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 (70 ℃ of meters), get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of dextrin, lactose, mix homogeneously, and adding concentration is 60% alcohol granulation, consumption is 45% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 75

A. extracting honeysuckle 75g, Radix Scutellariae 75g, Herba Schizonepetae 75g, Fructus Gardeniae 75g, Fructus Forsythiae 75g, Radix Scrophulariae 75g, Bombyx Batryticatus 47g, Radix Rehmanniae 115g, Rhizoma Belamcandae 25g, Radix Platycodonis 47g, Herba Menthae 47g, Periostracum Cicadae 47g, Radix Saposhnikoviae 47g, Radix Glycyrrhizae 24g;

B. the extraction of medicated powder I: get Radix Scutellariae and add 8 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 (55 ℃～60 ℃ meters), and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 5 times of water gagings, soak after 2 hours, adopt steam distillation 4 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 4 hours for the first time, decoct 2 hours for the second time, and collecting decoction filters, and relative density 1.04～1.20 when filtrate was concentrated into 85 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 10 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 85 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of lactose, PVP, mix homogeneously, and adding concentration is 40% alcohol granulation, consumption is 5% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add in the Polyethylene Glycol, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 76

A. extracting honeysuckle 69g, Radix Scutellariae 69g, Herba Schizonepetae 69g, Fructus Gardeniae 69g, Fructus Forsythiae 69g, Radix Scrophulariae 69g, Bombyx Batryticatus 40g, Radix Rehmanniae 100g, Rhizoma Belamcandae 20g, Radix Platycodonis 40g, Herba Menthae 40g, Periostracum Cicadae 40g, Radix Saposhnikoviae 40g, Radix Glycyrrhizae 20g;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 40%, reclaimed ethanol, and relative density 1.02～1.15 when being concentrated into 85 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 5 times of water gagings, soak after 1 hour, adopt steam distillation 6 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and relative density 1.04～1.20 when filtrate was concentrated into 70 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 12 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 75 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of starch, carboxymethyl starch sodium, mix homogeneously, and adding concentration is 70% alcohol granulation, consumption is 35% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add the combination of magnesium stearate, silica gel, Polyethylene Glycol, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 77

A. extracting honeysuckle 75g, Radix Scutellariae 69g, Herba Schizonepetae 75g, Fructus Gardeniae 69g, Fructus Forsythiae 75g, Radix Scrophulariae 75g, Bombyx Batryticatus 40, Radix Rehmanniae 115g, Rhizoma Belamcandae 25g, Radix Platycodonis 40g, Herba Menthae 40g, Periostracum Cicadae 40g, Radix Saposhnikoviae 47g, Radix Glycyrrhizae 20g;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol refluxs 2 times, each 4.5 hours, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 65 ℃～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 6 times of water gagings, soak after 2 hours, adopt steam distillation 2 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 3 times, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.15～1.20 in the time of 70～80 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 65%, left standstill 48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.35～1.45 in the time of 50～60 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add dextrin, mix homogeneously, and adding concentration is 80% alcohol granulation, consumption is 80% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add the combination of magnesium stearate, silica gel, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 78

A. extracting honeysuckle 72g, Radix Scutellariae 72g, Herba Schizonepetae 72g, Fructus Gardeniae 72g, Fructus Forsythiae 72g, Radix Scrophulariae 72g, Bombyx Batryticatus 43g, Radix Rehmanniae 108g, Rhizoma Belamcandae 22g, Radix Platycodonis 43g, Herba Menthae 43g, Periostracum Cicadae 43g, Radix Saposhnikoviae 43g, Radix Glycyrrhizae 22g;

B. the extraction of medicated powder I: get Radix Scutellariae and add 9 times of amount alcohol refluxs 2 times, each 1 hour, concentration of ethanol was 30%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 45 ℃～50 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 5 times of water gagings, soak after 5 hours, adopt steam distillation 1 hour, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 2 times, decoct 0.5 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.12～1.20 in the time of 50～60 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 45%, left standstill 4 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.15～1.25 in the time of 50～80 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add carboxymethyl starch sodium, mix homogeneously, and adding concentration is 55% alcohol granulation, consumption is 40% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add silica gel, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 79

A. get prescription, it is standby with embodiment 1 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol refluxs 3 times, each 1 hour, concentration of ethanol was 30%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 8 times of water gagings, soak after 0.5 hour, adopt steam distillation 1 hour, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 3 times, decoct 0.5 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.30 in the time of 80 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 80 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of dextrin, lactose, mix homogeneously, and adding concentration is 80% alcohol granulation, consumption is 2% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 80

A. get prescription, it is standby with embodiment 2 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 9 times of amount alcohol refluxs 2 times, each 1 hour, concentration of ethanol was 30%, reclaimed ethanol, and relative density 1.02～1.25 when being concentrated into 75 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 5 times of water gagings, soak after 5 hours, adopt steam distillation 1 hour, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 2 times, decoct 0.5 hour at every turn, and collecting decoction filters, and relative density 1.12～1.20 when filtrate was concentrated into 75 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 45%, left standstill 4 hours, filter; 4. reclaim ethanol, relative density 1.15～1.25 when being concentrated into 75 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II, the combination of adding, PVP, carboxymethyl starch sodium, mix homogeneously, adding concentration is 5% alcohol granulation, consumption is 80% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add silica gel, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 81

A. get prescription, it is standby with embodiment 9 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3 times of amount alcohol refluxs 2 times, each 1.5 hours, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 65 ℃～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 6 times of water gagings, soak after 2 hours, adopt steam distillation 2 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 3 times, the each decoction 1 hour, collecting decoction, filter, filtrate is concentrated into relative density 1.15～1.20 in the time of 70～80 ℃, puts cold: 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 65%, left standstill 48 hours, and filtered; 4. reclaim ethanol, be concentrated into, get medicated powder II 50～60 o'clock relative densities 1.35～1.45;

C. get it filled powder I, medicated powder II add the combination of starch, dextrin, lactose, PVP, carboxymethyl starch sodium, mix homogeneously, and adding concentration is 80% alcohol granulation, consumption is 80% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add the combination of magnesium stearate, silica gel, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 82

A. get prescription, it is standby with embodiment 7 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 3 times of water gagings, soak after 3 hours, adopt steam distillation 3 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and relative density 1.04～1.20 when filtrate was concentrated into 80 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 30%, left standstill 36 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 80 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of starch, dextrin, lactose, PVP, carboxymethyl starch sodium, mix homogeneously, and adding concentration is 10% alcohol granulation, consumption is 5% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add the combination of magnesium stearate, silica gel, Polyethylene Glycol, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 83

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 8 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 40%, reclaimed ethanol, relative density 1.02～1.15 when being concentrated into 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 4 times of water gagings, soak after 1 hour, adopt steam distillation 2 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of lactose, PVP, mix homogeneously, and adding concentration is 30% alcohol granulation, consumption is 45% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add in poly-7 glycol, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 84

A. get prescription, it is standby with embodiment 3 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 40～80%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 85 ℃～90 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 4 times of water gagings, soak after 3 hours, adopt steam distillation 6 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 85 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 50%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 85 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of dextrin, lactose, mix homogeneously, and adding concentration is 70% alcohol granulation, consumption is 50% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 85

A. get prescription, it is standby with embodiment 4 to write out a prescription;

The extraction of medicated powder I: get Radix Scutellariae and add 6 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 45 ℃～50 ℃, and drying gets medicated powder I;

B. the extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 2 times of water gagings, soak after 2 hours, adopt steam distillation 3 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 80 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 55%, left standstill 16 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 80 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add starch, mix homogeneously, and adding concentration is 75% alcohol granulation, consumption is 8% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add the magnesium stearate mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 86

A. get prescription, it is standby with embodiment 7 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 60%, reclaimed ethanol, was concentrated into relative density 1.10～1.15 in the time of 65 ℃, and drying gets medicated powder I;

The extraction of medicated powder II; 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 2 times of water gagings, soak after 1 hour, adopt steam distillation 6 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.14～1.20 in the time of 55 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 20 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 55 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add carboxymethyl starch sodium, mix homogeneously, and adding concentration is 50% alcohol granulation, consumption is 20% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add Polyethylene Glycol, mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 87

A. get prescription, it is standby with embodiment 8 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 6 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, and relative density 1.08～1.10 when being concentrated into 70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 4 times of water gagings, soak after 3 hours, adopt steam distillation 3 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and relative density 1.04～1.20 when filtrate was concentrated into 50 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 75%, left standstill 24 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 50 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of dextrin, PVP, mix homogeneously, and adding concentration is 45% alcohol granulation, consumption is 15% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; The combination that adds magnesium stearate, silica gel, mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 88

A. get prescription, it is standby with embodiment 5 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 35%, reclaimed ethanol, and relative density 1.07～1.15 when being concentrated into 58 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 2 times of water gagings, soak after 2 hours, adopt steam distillation 3 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and relative density 1.04～1.20 when filtrate was concentrated into 62 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 45%, left standstill 12 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 62 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add carboxymethyl starch sodium, mix homogeneously, and adding concentration is 60% alcohol granulation, consumption is 50% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add silica gel, mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 89

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.05～1.10 (55 ℃～60 ℃ meters), and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 2 times of water gagings, soak after 2 hours, adopt steam distillation 3 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.05～1.15 (70 ℃), puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 65%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 (70 ℃ of meters), get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of starch, dextrin, mix homogeneously, and adding concentration is that concentration is 55% alcohol granulation, consumption is 20% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add the magnesium stearate mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 90

A. get prescription, it is standby with embodiment 4 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 9 times of amount alcohol refluxs 3 times, 2 hours for the first time, 1 hour for the second time, concentration of ethanol was 85%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 65 ℃, and drying gets medicated powder I;

C. the extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 6 times of water gagings, soak after 4 hours, adopt steam distillation 7 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 2 times, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.25 in the time of 75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 40 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 75 ℃, get medicated powder II;

D. get it filled powder I, medicated powder II add the combination of dextrin, lactose, mix homogeneously, and adding concentration is 75% alcohol granulation, consumption is 60% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 91

A. get prescription, it is standby with embodiment 5 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 1 times of amount alcohol reflux 1 time, each 1 hour, concentration of ethanol was 35%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 50 ℃, and drying gets medicated powder I;

C. the extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 1 times of water gaging, soak after 1 hour, adopted steam distillation 1 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract: 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 2 times, decoct 1 hour at every turn, collecting decoction, filter, filtrate is concentrated into relative density 1.02～1.25 in the time of 60 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 15%, left standstill 6～40 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 60 ℃, get medicated powder II;

D. get it filled powder I, medicated powder II add the combination of starch, carboxymethyl starch sodium, mix homogeneously, and adding concentration is 75% alcohol granulation, consumption is 4% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add silica gel, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 92

A. get prescription, it is standby with embodiment 7 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 80%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55 ℃, and drying gets medicated powder I;

C. the extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 4 times of water gagings, soak after 1 hour, adopt steam distillation 5 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into 70 ℃ of relative densities 1.04～1.20, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

D. get it filled powder I, medicated powder II add carboxymethyl starch sodium, mix homogeneously, and adding concentration is 70% alcohol granulation, consumption is 5% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add Polyethylene Glycol, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 93

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 4 times of water gagings, soak after 1 hour, adopt steam distillation 3 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add starch, and the weight of starch is medicated powder I and medicated powder II weight sum 0.5～2 times, mix homogeneously, and adding concentration is 65% alcohol granulation, consumption is 14% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, the weight of magnesium stearate is 2% of medicated powder I and medicated powder II weight sum, and mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 94

A. get prescription, it is standby with embodiment 1 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 9 times of amount alcohol refluxs 3 times, each 1.5 hours, concentration of ethanol was 95%, reclaimed ethanol, was concentrated into relative density 1.01～1.35 in the time of 85 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 5 times of water gagings, soak after 4 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 2 times, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.01～1.35 in the time of 85 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 32 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.01～1.45 in the time of 90 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II spray into volatile oil, and mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 95

A. get prescription, it is standby with embodiment 3 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol refluxs 2 times, each 2 hours, concentration of ethanol was 30%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 4 times of water gagings, soak after 2 hours, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 2 times, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.25 in the time of 50～55 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 35%, left standstill 18 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.04～1.45 in the time of 50～90 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II spray into volatile oil, and mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 96

A. get prescription, it is standby with embodiment 4 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 1.5 hours, concentration of ethanol was 60%, reclaimed ethanol, was concentrated into relative density 1.02～1.30 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 1 times of water gaging, soak after 1 hour, adopted steam distillation 1 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.20 in the time of 60～80 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add adjuvant, and wherein adjuvant selects dextrin, lactose, mix homogeneously, and adding concentration is 75% alcohol granulation, consumption is 4% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add silica gel, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 97

A. get prescription, it is standby with embodiment 5 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 6 times of amount alcohol reflux secondaries, each 1.5 hours, concentration of ethanol was 90%, reclaimed ethanol, was concentrated into relative density 1.02～1.20 in the time of 45～50 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 3 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, and 2 hours for the first time, 1 hour for the second time, collecting decoction filtered, and filtrate is concentrated into relative density 1.05～1.20 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 16 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.20 in the time of 60～70 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add adjuvant, starch wherein, and mix homogeneously, adding concentration is 55% alcohol granulation, consumption is 25% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add Polyethylene Glycol, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 98

A. get prescription, it is standby with embodiment 6 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, 2 hours for the first time, 1 hour for the second time, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.06～1.25 in the time of 55～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 2 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, and 2 hours for the first time, 0.5 hour for the second time, collecting decoction filtered, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 12 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.30 in the time of 70～80 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add starch, and the weight of used starch is medicated powder I and medicated powder II weight sum 6 times, mix homogeneously, and adding concentration is 70% alcohol granulation, consumption is 50% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, the weight of used magnesium stearate is 0.1% of medicated powder I and medicated powder II weight sum, and mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 99

A. get prescription, it is standby with embodiment 7 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 60%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 1 hour, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add adjuvant, and adjuvant is selected from the combination of dextrin, lactose, and the weight of used adjuvant is medicated powder I and medicated powder II weight sum 0.5 times, mix homogeneously, and adding concentration is 30% alcohol granulation, consumption is 5% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add lubricant, lubricant is selected from one or several combinations of magnesium stearate, silica gel, weight with lubricator be 8% of medicated powder I and medicated powder II weight sum, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 100

A. get prescription, it is standby with embodiment 8 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 2 hours, adopted steam distillation 4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 70%, left standstill 18 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add adjuvant, adjuvant be selected from starch, dextrin, lactose combination, the weight of used adjuvant is medicated powder I and medicated powder II weight sum 3 times, mix homogeneously, adding concentration is 40% alcohol granulation, consumption is 30% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add lubricant, lubricant is selected from the combination of magnesium stearate, silica gel, Polyethylene Glycol, weight with lubricator be 2% of medicated powder I and medicated powder II weight sum, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 101

A. get prescription, it is standby with embodiment 9 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5.5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 55%, reclaimed ethanol, was concentrated into relative density 1.05～1.15 in the time of 55～65 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2.5 times of water gagings, soak after 1.5 hours, adopted steam distillation 3.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1.5 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.11 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 40%, left standstill 40 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.15 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add starch, and the weight of starch is medicated powder I and medicated powder II weight sum 2 times, mix homogeneously, and adding concentration is 60% alcohol granulation, consumption is 50% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, the weight of magnesium stearate is 2% of medicated powder I and medicated powder II weight sum, and mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 102

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7.5 times of amount alcohol reflux secondaries, each 3 hours, concentration of ethanol was 55%, reclaimed ethanol, was concentrated into relative density 1.05～1.15 in the time of 55～65 ℃, and drying gets medicated powder I; The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2.5 times of water gagings, soak after 1.5 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.11 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 40%, left standstill 40 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.15 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add starch, and the weight of starch is medicated powder I and medicated powder II weight sum 1 times, mix homogeneously, and adding concentration is 40% alcohol granulation, consumption is 15% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, the weight of magnesium stearate is 1% of medicated powder I and medicated powder II weight sum, and mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 103

(a). get prescription, it is standby with embodiment 1 to write out a prescription;

(b). above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 85% ethanol extraction 1 time, extracts 4 hours, reclaims ethanol, adds water and boils in right amount, filters filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 1 time, extracted 4 hours, collecting decoction, filter, filtrate is concentrated into that relative density is 1.03～1.25 in the time of 50～60 ℃, adding ethanol makes pure content reach 80% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.04～1.40 in the time of 50～60 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

(c). the powder of getting it filled sprays into volatile oil; Mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 104

(a). get prescription, it is standby with embodiment 3 to write out a prescription;

(b). above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 45% ethanol extraction 4 times, and each 0.5 hour, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 4 times, each 0.5 hour, collecting decoction, filter, filtrate is concentrated into that relative density is 1.03～1.25 in the time of 60～70 ℃, adding ethanol makes pure content reach 40～80% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.04～1.40 in the time of 70～80 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

(c). the powder of getting it filled adds the conventional adjuvant of capsule, granulates according to the conventional preparation method of capsule, sprays into volatile oil; Mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 105

(a). get prescription, it is standby with embodiment 5 to write out a prescription;

(b). above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 60% ethanol extraction 3 times, and each 2 hours, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, each 2 hours, collecting decoction, filter, filtrate is concentrated into that relative density is 1.03～1.25 in the time of 60 ℃, adding ethanol makes pure content reach 50% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.04～1.40 in the time of 50 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

(c). the powder of getting it filled adds the conventional adjuvant of capsule, granulates according to the conventional preparation method of capsule, sprays into volatile oil; Mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 106

(a). get prescription, it is standby with embodiment 7 to write out a prescription;

(b). above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 75% ethanol extraction 3 times, and per 3 hours, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 3 times, each 3 hours, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 60～80 ℃, adding ethanol makes pure content reach 65% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.10～1.30 in the time of 60～80 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

(c). the powder of getting it filled, add cane sugar powder, mix homogeneously, adding concentration is 75% alcohol granulation, consumption is 50% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 107

(a). get prescription, it is standby with embodiment 8 to write out a prescription;

(b). above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 55% ethanol extraction 2 times, and each 1 hour, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, each 1 hour, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 60～80 ℃, adding ethanol makes pure content reach 55～65% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.10～1.30 in the time of 60～80 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

(c). the powder of getting it filled, add granule adjuvant commonly used, mix homogeneously adds concentration and is 20% alcohol granulation; With particle drying, spray into volatile oil; Mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 108

(a). get prescription, it is standby with embodiment 10 to write out a prescription;

(b). above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 60% ethanol extraction 2 times, and 2 hours for the first time, 1 hour for the second time, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, 2 hours for the first time, 1 hour for the second time, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 60～80 ℃, adding ethanol makes pure content reach 55～65% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.10～1.30 in the time of 60～80 ℃, adds the Radix Scutellariae ethanol extract, concentrates, drying must get medicated powder;

(c). the powder of getting it filled, add cane sugar powder, mix homogeneously sprays into volatile oil; Mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 109

(a). get prescription, it is standby with embodiment 9 to write out a prescription;

(b). above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 65% ethanol extraction 3 times, and 3 hours for the first time, 1 hour for the second time, 1 hour for the third time, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; With medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae is extracted medicinal residues and the Fructus Gardeniae behind the volatile oil, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae decocts with water 3 times, 3 hours for the first time, 1 hour for the second time, 1 hour for the third time, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 60～80 ℃, add ethanol and make pure content reach 55～65% to leave standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.10～1.30 in the time of 60～80 ℃, add the Radix Scutellariae ethanol extract, concentrate, drying must get medicated powder;

(c). the powder of getting it filled, add PVP, mix homogeneously, adding concentration is 50% alcohol granulation, consumption is medicated powder and supplementary product consumption 15%; With particle drying, spray into volatile oil; Mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 110

(a). get prescription, it is standby with embodiment 7 to write out a prescription;

(b). above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 60% ethanol extraction 3 times, and 3 hours for the first time, 1 hour for the second time, 1 hour for the third time, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, 3 hours for the first time, 1 hour for the second time, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 70～80 ℃, adding ethanol makes pure content reach 55～65% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.10～1.30 in the time of 70～80 ℃, adds the Radix Scutellariae ethanol extract, concentrates, drying must get medicated powder;

(c). the powder of getting it filled, add starch, mix homogeneously, adding concentration is 75% alcohol granulation, consumption is 30% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Embodiment 111

(a). get prescription, it is standby with embodiment 10 to write out a prescription;

(b). above 14 flavors, Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected; Radix Scutellariae adds 65% ethanol extraction 2 times, and each 2 hours, reclaim ethanol, add water and boil in right amount, filter filtrate for later use while hot; Medicinal residues and Fructus Gardeniae, Fructus Forsythiae, Radix Scrophulariae, Bombyx Batryticatus, Radix Rehmanniae, Rhizoma Belamcandae, Radix Platycodonis, Periostracum Cicadae, Radix Glycyrrhizae that medicinal residues behind the Radix Scutellariae ethanol extraction and Flos Lonicerae, Herba Schizonepetae, Radix Saposhnikoviae, Herba Menthae are extracted behind the volatile oil decoct with water 2 times, 2 hours for the first time, 1 hour for the second time, collecting decoction, filter, filtrate is concentrated into that relative density is 1.06～1.11 in the time of 70 ℃, adding ethanol makes pure content reach 60% and leaves standstill, filter, filtrate recycling ethanol also is concentrated into that relative density is 1.16～1.20 in the time of 70 ℃, adds the Radix Scutellariae ethanol extract, concentrates, drying must get medicated powder;

(c). the powder of getting it filled, the combination of one or more of adjuvants such as adding cane sugar powder, lactose, starch, dextrin, lactose, PVP, carboxymethyl starch sodium, mix homogeneously, adding concentration is 70% alcohol granulation, the consumption capsule is 5%～50% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Mix homogeneously in the capsule for medicine of packing into, promptly gets colloid.

Embodiment 112

A. extracting honeysuckle 36g, Radix Scutellariae 36g, Herba Schizonepetae 36g, Fructus Gardeniae 36g, Fructus Forsythiae 36g, Radix Scrophulariae 36g, Bombyx Batryticatus 22g, Radix Rehmanniae 55g, Rhizoma Belamcandae 11g, Radix Platycodonis 22g, Herba Menthae 22g, Periostracum Cicadae 22g, Radix Saposhnikoviae 22g, Radix Glycyrrhizae 11g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol refluxs 3 times, each 3 hours, concentration of ethanol was 90%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 8 times of water gagings, soak after 5 hours, adopted steam distillation 1 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 3 times, decoct 3 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.30 in the time of 50 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 80 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of soluble starch, dextrin, and mix homogeneously, consumption are that 50% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 113

A. extracting honeysuckle 145g, Radix Scutellariae 145g, Herba Schizonepetae 145g, Fructus Gardeniae 145g, Fructus Forsythiae 145g, Radix Scrophulariae 145g, Bombyx Batryticatus 85g, Radix Rehmanniae 215g, Rhizoma Belamcandae 45g, Radix Platycodonis 85g, Herba Menthae 85g, Periostracum Cicadae 85g, Radix Saposhnikoviae 85g, Radix Glycyrrhizae 45g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 1 times of amount alcohol reflux secondary, each 2 hours, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.05～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 1 hour, adopted steam distillation 2～6 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 60 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add cane sugar powder, and mix homogeneously, consumption are that 8% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 114

A. extracting honeysuckle 145g, Radix Scutellariae 45g, Herba Schizonepetae 36g, Fructus Gardeniae 36g, Fructus Forsythiae 145g, Radix Scrophulariae 36g, Bombyx Batryticatus 22g, Radix Rehmanniae 55g, Rhizoma Belamcandae 11g, Radix Platycodonis 85g, Herba Menthae 85g, Periostracum Cicadae 22g, Radix Saposhnikoviae 85g, Radix Glycyrrhizae 45g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol refluxs 3 times, each 1 hour, concentration of ethanol was 30%, reclaimed ethanol, was concentrated into relative density 1.02～1.08 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 8 times of water gagings, soak after 0.5 hour, adopted steam distillation 8 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 1～3 time, decoct 0.5～3 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.20 in the time of 40～50 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.15 in the time of 60～70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add dextrin, and mix homogeneously, consumption are that 70% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 115

A. extracting honeysuckle 86.70g, Radix Scutellariae 86.70g, Herba Schizonepetae 86.70g, Fructus Gardeniae (stir-fry) 86.70g, Fructus Forsythiae 86.70g, Radix Scrophulariae 86.70g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 51.55g, Radix Rehmanniae 129.81g, Rhizoma Belamcandae 26.70g, Radix Platycodonis 51.55g, Herba Menthae 51.55g, Radix Saposhnikoviae 51.55g, Periostracum Cicadae 51.55g, Radix Glycyrrhizae 26.70g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol refluxs 2 times, each 2 hours, concentration of ethanol was 80%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 7 times of water gagings, soak after 4 hours, adopted steam distillation 5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials branches and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 3 times, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into 50 ℃ of relative densities 1.02～1.30, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 65%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into, get medicated powder II 50 ℃ of meter relative densities 1.05～1.45;

C. get it filled powder I, medicated powder II, add cane sugar powder, the soluble starch of 4 times of amounts, the mixture of dextrin, wherein cane sugar powder: soluble starch: dextrin is 1: 1: 2, consumption is that 10% water of medicated powder and supplementary product consumption is granulated, with particle drying, spray into volatile oil, promptly get granule.

Embodiment 116

A. extracting honeysuckle 53.54g, Radix Scutellariae 53.54g, Herba Schizonepetae 53.54g, Fructus Gardeniae (stir-fry) 53.54g, Fructus Forsythiae 53.54g, Radix Scrophulariae 53.54g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 33.57g, Radix Rehmanniae 86.27g, Rhizoma Belamcandae 17.54g, Radix Platycodonis 33.57g, Herba Menthae 33.57g, Radix Saposhnikoviae 33.57g, Periostracum Cicadae 33.57g, Radix Glycyrrhizae 17.54g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 2 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 60 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 36 hours, filter; 4. reclaim ethanol, be concentrated into, get medicated powder II 70 ℃ of relative densities 1.14～1.25;

C. get it filled powder I, medicated powder II add the dextrin mix homogeneously, and consumption is that 30% water of medicated powder and supplementary product consumption is granulated, and with particle drying, sprays into volatile oil, promptly gets granule.

Embodiment 117

A. extracting honeysuckle 86.70g, Radix Scutellariae 53.54g, Herba Schizonepetae 86.70g, Fructus Gardeniae (stir-fry) 53.54g, Fructus Forsythiae 86.70g, Radix Scrophulariae 53.54g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 51.55g, Radix Rehmanniae 86.27g, Rhizoma Belamcandae 26.70g, Radix Platycodonis 33.57g, Herba Menthae 51.55g, Radix Saposhnikoviae 33.57g, Periostracum Cicadae 51.55g, Radix Glycyrrhizae 17.54g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol refluxs 3 times, 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, concentration of ethanol was 90%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 50 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, double water gaging, soak after 5 hours, adopted steam distillation 8 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 3 hours for the first time 3 times, 2 hours for the second time, 1 hour for the third time, collecting decoction, filter, filtrate is concentrated into relative density 1.02～1.30 in the time of 80 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 40 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 50 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add soluble starch, and mix homogeneously, consumption are that 70% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 118

A. extracting honeysuckle 75g, Radix Scutellariae 75g, Herba Schizonepetae 75g, Fructus Gardeniae 75g, Fructus Forsythiae 75g, Radix Scrophulariae 75g, Bombyx Batryticatus 47g, Radix Rehmanniae 115g, Rhizoma Belamcandae 25g, Radix Platycodonis 47g, Herba Menthae 47g, Periostracum Cicadae 47g, Radix Saposhnikoviae 47g, Radix Glycyrrhizae 24g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol refluxs 2 times, 2 hours for the first time, 1 hour for the second time, concentration of ethanol was 30%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 4.5 hours, adopted steam distillation 7 hours, and collected volatile oil device preservation in addition, medicinal residues continue to extract: 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 2 times, the each decoction 2 hours, collecting decoction filters, filtrate is concentrated into relative density 1.02～1.30 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 55%, left standstill 20 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 60 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of cane sugar powder, dextrin, and mix homogeneously, consumption are that 40% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 119

A. extracting honeysuckle 69g, Radix Scutellariae 69g, Herba Schizonepetae 69g, Fructus Gardeniae 69g, Fructus Forsythiae 69g, Radix Scrophulariae 69g, Bombyx Batryticatus 40g, Radix Rehmanniae 100g, Rhizoma Belamcandae 20g, Radix Platycodonis 40g, Herba Menthae 40g, Periostracum Cicadae 40g, Radix Saposhnikoviae 40g, Radix Glycyrrhizae 20g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 6 times of amount alcohol refluxs 2 times, each 2 hours, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 55 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 3 hours, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 2 times, decoct 2.5 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.30 in the time of 55 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 25%, left standstill 40 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 55 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of cane sugar powder, soluble starch, and mix homogeneously, consumption are that 60% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 120

A. extracting honeysuckle 75g, Radix Scutellariae 69g, Herba Schizonepetae 75g, Fructus Gardeniae 69g, Fructus Forsythiae 75g, Radix Scrophulariae 75g, Bombyx Batryticatus 40, Radix Rehmanniae 115g, Rhizoma Belamcandae 25g, Radix Platycodonis 40g, Herba Menthae 40g, Periostracum Cicadae 40g, Radix Saposhnikoviae 47g, Radix Glycyrrhizae 20g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 7 times of water gagings, soak after 3 hours, adopted steam distillation 6 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 3 hours for the first time, decocted 2 hours for the second time, collecting decoction filters, filtrate is concentrated into relative density 1.04～1.20 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 40%, left standstill 36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 60～75 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add cane sugar powder, and mix homogeneously, consumption are that 8% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 121

A. extracting honeysuckle 72g, Radix Scutellariae 72g, Herba Schizonepetae 72g, Fructus Gardeniae 72g, Fructus Forsythiae 72g, Radix Scrophulariae 72g, Bombyx Batryticatus 43g, Radix Rehmanniae 108g, Rhizoma Belamcandae 22g, Radix Platycodonis 43g, Herba Menthae 43g, Periostracum Cicadae 43g, Radix Saposhnikoviae 43g, Radix Glycyrrhizae 22g;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5.5 times of amount alcohol reflux secondaries, each 1.5 hours, concentration of ethanol was 40～80%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5.5 times of water gagings, soak after 2.5 hours, adopted steam distillation 2.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 1～3 hour for the first time, decocted 0.5～2 hour for the second time, collecting decoction filters, filtrate is concentrated into relative density 1.04～1.20 in the time of 74 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 74 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of cane sugar powder, soluble starch, dextrin, and mix homogeneously, consumption are that 15% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 122

A. get prescription, it is standby with embodiment 1 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 9 times of amount alcohol refluxs 3 times, 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, concentration of ethanol was 30～90%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 7 times of water gagings, soak after 3 hours, adopted steam distillation 4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 3 hours for the first time 3 times, 2 hours for the second time, 0.5 hour for the third time, collecting decoction, filter, filtrate is concentrated into relative density 1.02～1.30 (50～80 ℃), puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 75%, left standstill 48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 80 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add soluble starch, and mix homogeneously, consumption are that 70% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 123

A. get prescription, it is standby with embodiment 3 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol refluxs 3 times, each 1 hour, concentration of ethanol was 40%, reclaimed ethanol, and relative density 1.04～1.20 when being concentrated into 85 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 7 times of water gagings, soak after 4 hours, adopt steam distillation 2 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 2 times, decoct 3 hours at every turn, and collecting decoction filters, and relative density 1.02～1.10 when filtrate was concentrated into 75 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 45%, left standstill 12 hours, filter; 4. reclaim ethanol, relative density 1.15～1.25 when being concentrated into 75 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of cane sugar powder, soluble starch, and mix homogeneously, consumption are that 70% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 124

A. get prescription, it is standby with embodiment 5 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol refluxs 2 times, each 1 hour, concentration of ethanol was 30%, reclaimed ethanol, relative density 1.02～1.25 when being concentrated into 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 0.5 hour, adopted steam distillation 3.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water 2 times, and 3 hours for the first time, 1 hour for the second time, collecting decoction filtered, and relative density 1.09～1.20 when filtrate was concentrated into 50 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 55%, left standstill 24 hours, filter; 4. reclaim ethanol, relative density 1.15～1.25 when being concentrated into 60 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add dextrin, and mix homogeneously, consumption are that 5% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 125

A. get prescription, it is standby with embodiment 9 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 8 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 80%, reclaimed ethanol, and relative density 1.02～1.15 when being concentrated into 70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 6 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and relative density 1.04～1.20 when filtrate was concentrated into 70 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 8 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add dextrin, and mix homogeneously, consumption are that 50% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 126

A. get prescription, it is standby with embodiment 2 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 80%, reclaimed ethanol, and relative density 1.02～1.15 when being concentrated into 80 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 3 hours, adopted steam distillation 6 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into 60 o'clock relative densities 1.04～1.20, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 36 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 50 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of cane sugar powder, soluble starch, and mix homogeneously, consumption are that 50% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 127

A. get prescription, it is standby with embodiment 4 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 50%, reclaimed ethanol, relative density 1.02～1.15 when being concentrated into 75 ℃～80 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into 75 ℃ of relative densities 1.04～1.20, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 30%, left standstill 16 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 75 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add soluble starch, and mix homogeneously, consumption are that 35% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 128

A. get prescription, it is standby with embodiment 8 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3 times of amount alcohol reflux secondaries, each 2 hours. concentration of ethanol is 40～80%, reclaims ethanol, relative density 1.02～1.15 when being concentrated into 45 ℃～50 ℃, drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2 times of water gagings, soak after 2 hours, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and relative density 1.04～1.20 when filtrate was concentrated into 50 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 30%, left standstill 16 hours, filter: 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 70 ℃, medicated powder II;

C. get it filled powder I, medicated powder II add one or more combination of adjuvants such as cane sugar powder, soluble starch, dextrin, ring adjuvant, and mix homogeneously, consumption are that 30% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 129

A. get prescription, it is standby with embodiment 6 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into 55 ℃ of relative densities 1.07～1.15, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2 times of water gagings, soak after 2 hours, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and relative density 1.04～1.12 when filtrate was concentrated into 55 ℃, put cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 25%, left standstill 20 hours, filter; 4. reclaim ethanol, relative density 1.14～1.22 when being concentrated into 55 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of cane sugar powder, dextrin, and mix homogeneously, consumption are that 30% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 130

A. get prescription, it is standby with embodiment 5 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 9 times of amount alcohol refluxs 2 times, 2 hours for the first time, 1 hour for the second time, concentration of ethanol was 45%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 65 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 3.5 hours, adopted steam distillation 3.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decocted 3 hours for the first time, decocted 2 hours for the second time, collecting decoction filters, filtrate is concentrated into relative density 1.04～1.20 in the time of 75 ℃, put cold: 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 15%, left standstill 40 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 75 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add the combination of cane sugar powder, dextrin, and consumption is that 8% water of medicated powder and supplementary product consumption is granulated, and with particle drying, sprays into volatile oil, promptly gets granule.

Embodiment 131

A. get prescription, it is standby with embodiment 4 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 6 times of amount alcohol refluxs 2 times, each 1 hour, concentration of ethanol was 55%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 50 ℃～65 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2 times of water gagings, soak after 2 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 3 hours for the first time, decocted 2 hours for the second time, collecting decoction filters, filtrate is concentrated into relative density 1.04～1.20 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 25%, left standstill 18 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 66 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add one or more combination of adjuvants such as cane sugar powder, soluble starch, dextrin, ring adjuvant, and consumption is that 8～50% water of medicated powder and supplementary product consumption is granulated, and with particle drying, sprays into volatile oil, promptly gets granule.

Embodiment 132

A. get prescription, it is standby with embodiment 8 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 8 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 58 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 3 hours, adopted steam distillation 5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 30 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add dextrin, and mix homogeneously, consumption are that 18% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 133

A. get prescription, it is standby with embodiment 7 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 6.5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 55%, reclaimed ethanol, was concentrated into relative density 1.02～1.15 in the time of 57 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2.5 times of water gagings, soak after 2.5 hours, adopted steam distillation 2.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 25%, left standstill 25 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add soluble starch, and mix homogeneously, consumption are that 25% water of medicated powder and supplementary product consumption is granulated, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 134

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add one or both combination of soluble starch, cyclodextrin adjuvant, and the amount of used adjuvant is medicated powder I and medicated powder II weight 0.4～3 times, and mix homogeneously adds water and granulates, and consumption is 10～30% of medicated powder and a supplementary product consumption.

Embodiment 135

A. get prescription, it is standby with embodiment 1 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 12 times of amount alcohol refluxs 3 times, each 3 hours, concentration of ethanol was 95%, reclaimed ethanol, was concentrated into relative density 1.00～1.35 in the time of 85 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 8 times of water gagings, soak after 5 hours, adopted steam distillation 8 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 3 times, decoct 3 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.01～1.35 in the time of 85 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.01～1.45 in the time of 50～90 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add granule adjuvant commonly used and granulate, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 136

A. get prescription, it is standby with embodiment 2 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 1 times of amount alcohol reflux 1 time, extracted 3 hours, concentration of ethanol is 30%, reclaims ethanol, is concentrated into relative density 1.03～1.35 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 1 times of water gaging, soak after 0.5 hour, adopted steam distillation 1 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 1 time, extract 3 hours, and collecting decoction filters, and filtrate is concentrated into relative density 1.05～1.35 in the time of 50 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 10%, left standstill 4 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.00～1.45 in the time of 50 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add granule adjuvant commonly used and granulate, and with particle drying, spray into volatile oil, promptly get granule.

Embodiment 137

A. get prescription, it is standby with embodiment 4 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol reflux secondaries, each 1 hour, concentration of ethanol was 90%, reclaimed ethanol, was concentrated into relative density 1.02～1.30 in the time of 80 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 7 times of water gagings, soak after 1 hour, adopted steam distillation 1 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.02～1.30 in the time of 60～80 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add the combination of cane sugar powder, soluble starch, and water is granulated, and consumption is 50% of medicated powder and a supplementary product consumption, with particle drying, sprays into volatile oil, promptly gets granule.

Embodiment 138

A. get prescription, it is standby with embodiment 5 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.02～1.30 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 1 times of water gaging, soak after 4 hours, adopted steam distillation 7 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 8～36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.30 in the time of 60～80 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add dextrin, and water is granulated, and consumption is 8% of medicated powder and a supplementary product consumption, with particle drying, sprays into volatile oil, promptly gets granule.

Embodiment 139

A. get prescription, it is standby with embodiment 6 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, each 1.5 hours, concentration of ethanol was 60%, reclaimed ethanol, was concentrated into relative density 1.02～1.30 in the time of 45～80 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 2 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 30%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.03～1.30 in the time of 60～80 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add one or more combination of adjuvants such as cane sugar powder, soluble starch, dextrin, ring adjuvant, and water is granulated, and consumption is 10% of medicated powder and a supplementary product consumption, with particle drying, sprays into volatile oil, promptly gets granule.

Embodiment 140

A. get prescription, it is standby with embodiment 7 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 2 hours, adopted steam distillation 4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add soluble starch, and the amount of used soluble starch is medicated powder I and medicated powder II weight 6 times, mix homogeneously, and water is granulated, and consumption is 30% of medicated powder and a supplementary product consumption, with particle drying, sprays into volatile oil, promptly gets granule.

Embodiment 141

A. get prescription, it is standby with embodiment 8 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 60%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 1 hour, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 20%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add the combination of cane sugar powder, dextrin, and the amount of used adjuvant is medicated powder I and medicated powder II weight 3 times, mix homogeneously, and water is granulated, and consumption is 10% of medicated powder and a supplementary product consumption, with particle drying, sprays into volatile oil, promptly gets granule.

Embodiment 142

A. get prescription, it is standby with embodiment 9 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, each 1.5 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1.5 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 50%, left standstill 20 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. get it filled powder I, medicated powder II add cane sugar powder, and the amount of used cane sugar powder is medicated powder I and medicated powder II weight 0.3 times, mix homogeneously, and water is granulated, and consumption is 20% of medicated powder and a supplementary product consumption, with particle drying, sprays into volatile oil, promptly gets granule.

Embodiment 143

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together. and add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add soluble starch, and the amount of used soluble starch is medicated powder I and medicated powder II weight 3 times, and mix homogeneously adds water and granulates, and consumption is 20% of medicated powder and a supplementary product consumption, makes granule.

Embodiment 144

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add cyclodextrin, and the amount of used cyclodextrin is medicated powder I and medicated powder II weight 2 times, and mix homogeneously adds water and granulates, and consumption is 15% of medicated powder and a supplementary product consumption, makes granule.

Embodiment 145

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add soluble starch, and the amount of used soluble starch is medicated powder I and medicated powder II weight 1 times, and mix homogeneously adds water and granulates, and consumption is 15% of medicated powder and a supplementary product consumption, makes granule.

Embodiment 146

A. extracting honeysuckle 36g, Radix Scutellariae 36g, Herba Schizonepetae 36g, Fructus Gardeniae 36g, Fructus Forsythiae 36g, Radix Scrophulariae 36g, Bombyx Batryticatus 22g, Radix Rehmanniae 55g, Rhizoma Belamcandae 11g, Radix Platycodonis 22g, Herba Menthae 22g, Periostracum Cicadae 22g, Radix Saposhnikoviae 22g, Radix Glycyrrhizae 11g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 12 times of amount alcohol refluxs 3 times, 3 hours for the first time, 2 hours for the second time, 1 hour for the third time, concentration of ethanol was 90%, reclaimed ethanol, was concentrated into relative density 1.03～1.35 in the time of 70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 8 times of water gagings, soak after 5 hours, adopted steam distillation 8 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 3 times, decoct 3 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.30 in the time of 80 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 85%, left standstill 48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 90 ℃, drying gets medicated powder I;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 30min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 60min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 60min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 147

A. extracting honeysuckle 145g, Radix Scutellariae 145g, Herba Schizonepetae 145g, Fructus Gardeniae 145g, Fructus Forsythiae 145g, Radix Scrophulariae 145g, Bombyx Batryticatus 85g, Radix Rehmanniae 215g, Rhizoma Belamcandae 45g, Radix Platycodonis 85g, Herba Menthae 85g, Periostracum Cicadae 85g, Radix Saposhnikoviae 85g, Radix Glycyrrhizae 45g;

B. the extraction of medicated powder I: get Radix Scutellariae and add 1 times of amount alcohol reflux 1 time, 3 hours, concentration of ethanol was 30%, reclaimed ethanol, was concentrated into relative density 1.03～1.35 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 1 times of water gaging, soak after 0.5 hour, adopted steam distillation 1 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 1 time, decoct 0.5 hour, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.30 in the time of 50 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 10%, left standstill 4 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 50 ℃, drying gets medicated powder I;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 5min, gets volatile oil Emulsion; Get glycerol, vegetable oil, Polyethylene Glycol, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 10min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 10min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 148

A. extracting honeysuckle 145g, Radix Scutellariae 45g, Herba Schizonepetae 36g, Fructus Gardeniae 36g, Fructus Forsythiae 145g, Radix Scrophulariae 36g, Bombyx Batryticatus 22g, Radix Rehmanniae 55g, Rhizoma Belamcandae 11g, Radix Platycodonis 85g, Herba Menthae 85g, Periostracum Cicadae 22g, Radix Saposhnikoviae 85g, Radix Glycyrrhizae 45g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 9 times of amount alcohol refluxs 2 times, 3 hours for the first time, 1 hour for the second time, each 1～3 hour, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.03～1.35 in the time of 50 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 4.5 times of water gagings, soak after 3.5 hours, adopted steam distillation 3.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 2 times, decoct 2.5 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.30 in the time of 60 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 15%, left standstill 15 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 35 ℃, drying gets medicated powder I;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 10min, gets volatile oil Emulsion; Get glycerol, Polyethylene Glycol, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 20min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 20min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 149

A. extracting honeysuckle 86.70g, Radix Scutellariae 86.70g, Herba Schizonepetae 86.70g, Fructus Gardeniae (stir-fry) 86.70g, Fructus Forsythiae 86.70g, Radix Scrophulariae 86.70g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 51.55g, Radix Rehmanniae 129.81g, Rhizoma Belamcandae 26.70g, Radix Platycodonis 51.55g, Herba Menthae 51.55g, Radix Saposhnikoviae 51.55g, Periostracum Cicadae 51.55g, Radix Glycyrrhizae 26.70g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol reflux secondaries, each 3 hours, concentration of ethanol was 80%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 65 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 7 times of water gagings, soak after 3 hours, adopted steam distillation 7 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 40 hours, filter; 4. reclaim ethanol, relative density 1.14～1.25 when being concentrated into 80 ℃, and drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 20min, gets volatile oil Emulsion; Get glycerol, vegetable oil, Tween 80, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 20min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 10min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 150

A. extracting honeysuckle 53.54g, Radix Scutellariae 53.54g, Herba Schizonepetae 53.54g, Fructus Gardeniae (stir-fry) 53.54g, Fructus Forsythiae 53.54g, Radix Scrophulariae 53.54g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 33.57g, Radix Rehmanniae 86.27g, Rhizoma Belamcandae 17.54g, Radix Platycodonis 33.57g, Herba Menthae 33.57g, Radix Saposhnikoviae 33.57g, Periostracum Cicadae 33.57g, Radix Glycyrrhizae 17.54g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol reflux secondaries, got 2 hours for the first time, 1.5 hours for the second time, concentration of ethanol was 75%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 62 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 2.5 times of water gagings, soak after 1.5 hours, adopted steam distillation 2.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, and 2 hours for the first time, 1 hour for the second time, collecting decoction filtered, and filtrate is concentrated into relative density 1.04～1.20 in the time of 64 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 55%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 64 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 8min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 40min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 40min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 151

A. extracting honeysuckle 86.70g, Radix Scutellariae 53.54g, Herba Schizonepetae 86.70g, Fructus Gardeniae (stir-fry) 53.54g, Fructus Forsythiae 86.70g, Radix Scrophulariae 53.54g, Bombyx Batryticatus (processed with Rhizoma Zingiberis Recens) 51.55g, Radix Rehmanniae 86.27g, Rhizoma Belamcandae 26.70g, Radix Platycodonis 33.57g, Herba Menthae 51.55g, Radix Saposhnikoviae 33.57g, Periostracum Cicadae 51.55g, Radix Glycyrrhizae 17.54g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5.5 times of amount alcohol reflux secondaries, 1 hour for the first time, 2 hours for the second time, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 61 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 6.5 times of water gagings, soak after 3.5 hours, adopted steam distillation 3.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1.5 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 60 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 12 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 60 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 30min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 10min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 152

A. extracting honeysuckle 75g, Radix Scutellariae 75g, Herba Schizonepetae 75g, Fructus Gardeniae 75g, Fructus Forsythiae 75g, Radix Scrophulariae 75g, Bombyx Batryticatus 47g, Radix Rehmanniae 115g, Rhizoma Belamcandae 25g, Radix Platycodonis 47g, Herba Menthae 47g, Periostracum Cicadae 47g, Radix Saposhnikoviae 47g, Radix Glycyrrhizae 24g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 8 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 50%, reclaimed ethanol, was concentrated into relative density 1.10～1.25 in the time of 55 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 3 times of water gagings, soak after 1 hour, adopted steam distillation 6 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, quiet 36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 10min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing, with homogenize machine homogenize 30min, add volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 12.78%, volatile oil 0.14%, vegetable oil 24.83%, glycerol 1.25%, water 5%, the soft capsule content of tween 56%; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 153

A. extracting honeysuckle 69g, Radix Scutellariae 69g, Herba Schizonepetae 69g, Fructus Gardeniae 69g, Fructus Forsythiae 69g, Radix Scrophulariae 69g, Bombyx Batryticatus 40g, Radix Rehmanniae 100g, Rhizoma Belamcandae 20g, Radix Platycodonis 40g, Herba Menthae 40g, Periostracum Cicadae 40g, Radix Saposhnikoviae 40g, Radix Glycyrrhizae 20g;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.10～1.25 in the time of 58 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 3 times of water gagings, soak after 2 hours, adopted steam distillation 5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 45%, left standstill 18 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 25min, gets volatile oil Emulsion; Get glycerol, Polyethylene Glycol, medicated powder I and medicated powder II, mixing, with homogenize machine homogenize 25min, add volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 25min, make medicated powder 8%, volatile oil 0.2%, polyethylene glycol 6000 34%, glycerol 1.6%, water 16.2%, the soft capsule content of polysorbate40 %; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 154

A. extracting honeysuckle 75g, Radix Scutellariae 69g, Herba Schizonepetae 75g, Fructus Gardeniae 69g, Fructus Forsythiae 75g, Radix Scrophulariae 75g, Bombyx Batryticatus 40, Radix Rehmanniae 115g, Rhizoma Belamcandae 25g, Radix Platycodonis 40g, Herba Menthae 40g, Periostracum Cicadae 40g, Radix Saposhnikoviae 47g, Radix Glycyrrhizae 20g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 71%, reclaimed ethanol, was concentrated into relative density 1.10～1.25 in the time of 55～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 1.5 times of water gagings, soak after 1.5 hours, adopted steam distillation 2.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 35%, left standstill 15 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 15min, gets volatile oil Emulsion; Get glycerol, vegetable oil, Polyethylene Glycol, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 15min, make medicated powder 30%, volatile oil 0.5%, vegetable oil 30%, glycerol 1.0%, water 23.5%, tween 10%, the soft capsule content of Macrogol 4000 5%; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 155

A. extracting honeysuckle 72g, Radix Scutellariae 72g, Herba Schizonepetae 72g, Fructus Gardeniae 72g, Fructus Forsythiae 72g, Radix Scrophulariae 72g, Bombyx Batryticatus 43g, Radix Rehmanniae 108g, Rhizoma Belamcandae 22g, Radix Platycodonis 43g, Herba Menthae 43g, Periostracum Cicadae 43g, Radix Saposhnikoviae 43g, Radix Glycyrrhizae 22g are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 10min, gets volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 12.61%, volatile oil 0.14%, substrate 25%, glycerol 1.25%, water 5%, the soft capsule content of tween 56%, described substrate is a kind of or combination in any in vegetable oil, Polyethylene Glycol or the Tween 80; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 156

A. get prescription, embodiment 3 is standby for prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol refluxs 2 times, each 1 hour, concentration of ethanol was 90%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, its excess-three distinguishes the flavor of respectively that water cleans up except that Flos Lonicerae, merge together then, add 5 times of water gagings, soak after 5 hours, adopted steam distillation 7.5 hours, and collected volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials water respectively clean up, with the medicinal residues behind the extraction volatile oil such as Radix Scutellariae medicinal residues and Flos Lonicerae, decoct with water 1 time, decocted 3 hours, collecting decoction filters, filtrate is concentrated into relative density 1.02～1.30 in the time of 70 ℃, put cold: 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 35%, left standstill 26 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 50 ℃, get medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 12min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 55min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 55min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 157

A. get prescription, embodiment 4 is standby for prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2.5 times of amount alcohol refluxs 2 times, 3 hours for the first time, 1 hour for the second time, concentration of ethanol was 85%, reclaimed ethanol, was concentrated into relative density 1.02～1.25 in the time of 75 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, its excess-three distinguishes the flavor of respectively that water cleans up except that Flos Lonicerae, merge together then, add 5.5 times of water gagings, soak after 1 hour, adopted steam distillation 0.5 hour, and collected volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials water respectively clean up, and the medicinal residues with behind the extraction volatile oil such as Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 1 time, decoct 1 hour, and collecting decoction filters, and filtrate is concentrated into relative density 1.02～1.30 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 75%, left standstill 20 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 40 ℃, get medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 18min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 18min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 18min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 158

A. get prescription, embodiment 6 is standby for prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4.5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 83%, reclaimed ethanol, was concentrated into relative density 1.10～1.25 in the time of 57 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 3.5 times of water gagings, soak after 2.5 hours, adopted steam distillation 1.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 3 hours for the first time, decoct 2 hours for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 50 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 75%, left standstill 18 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 30min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 15min, make medicated powder 40%, volatile oil 2.5%, vegetable oil 10%, glycerol 3.0%, water 14.5%, the soft capsule content of tween 30%; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 159

A. get prescription, embodiment 7 is standby for prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, each 1 hour, concentration of ethanol was 52%, reclaimed ethanol, was concentrated into relative density 1.10～1.25 in the time of 55～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 6 times of water gagings, soak after 2 hours, adopted steam distillation 5.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 45 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 53%, left standstill 42 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 40 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 45min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 40min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 45min, make medicated powder 50%, volatile oil 0.2%, vegetable oil 30%, glycerol 1.0%, water 3.8%, the soft capsule content of tween 15%; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 160

A. get prescription, embodiment 8 is standby for prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3 times of amount alcohol reflux secondaries, each 3 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.10～1.25 in the time of 56 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 7 times of water gagings, soak after 4 hours, adopted steam distillation 2.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours for the first time, decoct 2 hours for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 50 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 35%, left standstill 6 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 15min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 6.50%, volatile oil 2%, vegetable oil 56%, glycerol 3%, water 15%, the soft capsule content of tween 17.5%; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 161

A. get prescription, embodiment 10 is standby for prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3.5 times of amount alcohol reflux secondaries, each 3 hours, concentration of ethanol was 48%, reclaimed ethanol, was concentrated into relative density 1.10～1.25 in the time of 55～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 8.5 times of water gagings, soak after 0.5 hour, adopted steam distillation 0.5 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 35%, left standstill 35 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 60min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 60min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 60min, make medicated powder 20%, volatile oil 1%, vegetable oil 20%, glycerol 2%, water 30%, the soft capsule content of tween 27%; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 162

A. get prescription, embodiment 2 is standby for prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 71%, reclaimed ethanol, was concentrated into relative density 1.10～1.25 in the time of 55～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 1.5 times of water gagings, soak after 1.5 hours, adopted steam distillation 2.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 35%, left standstill 15 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 20min, gets volatile oil Emulsion; Get glycerol, Polyethylene Glycol, medicated powder I and medicated powder II, mixing, with homogenize machine homogenize 25min, add volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 25%, volatile oil 0.8%, glycerol 6%, water 30%, tween 13.2%, the soft capsule content of Macrogol 4000 25%; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 163

A. get prescription, embodiment 7 is standby for prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, 2 hours for the first time, 1 hour for the second time, concentration of ethanol was 45%, reclaimed ethanol, was concentrated into relative density 1.10～1.25 in the time of 57 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 6.5 times of water gagings, soak after 4 hours, adopted steam distillation 6.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 75%, left standstill 16 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 60 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 15min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 15min, make medicated powder 35%, volatile oil 2.5%, vegetable oil 20%, glycerol 1.0%, water 32.5%, tween 10%, soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 164

A. get prescription, embodiment 1 is standby for prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 11 times of amount alcohol refluxs 2 times, each 2 hours, concentration of ethanol was 95%, reclaimed ethanol, was concentrated into relative density 1.01～1.35 in the time of 75～85 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 7 times of water gagings, soak after 2 hours, adopted steam distillation 2.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 3 times, and 2 hours for the first time, 1 hour for the second time, 0.5 hour for the third time, collecting decoction filtered, filtrate is concentrated into relative density 1.01～1.35 in the time of 70～85 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 75%, left standstill 36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.01～1.45 in the time of 70～90 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 25min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 50min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 50min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 165

A. get prescription, embodiment 2 is standby for prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 1～12 times of amount alcohol reflux 2 times, 3 hours for the first time, 2 hours for the second time, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 45～85 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 4 times of water gagings, soak after 4 hours, adopted steam distillation 4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 2 times, and 3 hours for the first time, 1 hour for the second time, collecting decoction filtered, and filtrate is concentrated into relative density 1.05～1.25 in the time of 50～85 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 10～85%, left standstill 4～48 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.45 in the time of 50～90 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 8min, gets volatile oil Emulsion; Get glycerol, poly-7 glycol, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 12min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 12min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 166

A. get prescription, embodiment 4 is standby for prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol refluxs 2 times, each 2.5 hours, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.10～1.15 in the time of 50 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae four Chinese medicine material, merge together, add 3 times of water gagings, soak after 3 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water 2 times, decoct 1.5 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.08～1.15 in the time of 50 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 25%, left standstill 16 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.08～1.15 in the time of 50 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 5～30min, gets volatile oil Emulsion; Get glycerol, Tween 80, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 10～60min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 10～60min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 167

A. get prescription, embodiment 4 is standby for prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 10 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 90%, reclaimed ethanol, was concentrated into relative density 1.02～1.30 in the time of 80 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 7 times of water gagings, soak after 4 hours, adopted steam distillation 7 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 36 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.02～1.30 in the time of 60～80 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 20min, gets volatile oil Emulsion; Get glycerol, vegetable oil, Polyethylene Glycol or Tween 80, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 40min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 40min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 168

A. get prescription, it is standby with embodiment 5 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 2 times of amount alcohol reflux secondaries, each 1 hour, concentration of ethanol was 40%, reclaimed ethanol, was concentrated into relative density 1.02～1.30 in the time of 45 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 1 times of water gaging, soak after 1 hour, adopted steam distillation 1 hour, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol; Add ethanol and make and contain the alcohol amount and reach 20%, left standstill 8 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.03～1.30 in the time of 60～80 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 8min, gets volatile oil Emulsion; Get glycerol, vegetable oil, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 20min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 20min, promptly gets soft capsule content; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 169

A. get prescription, it is standby with embodiment 6 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, 2 hours for the first time, 1.5 hours for the second time, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.02～1.30 in the time of 60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 2 hours, adopted steam distillation 2 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1 hour at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.30 in the time of 60～75 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 30%, left standstill 12 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.30 in the time of 60～80 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 15min, gets volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 15min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 15min, promptly gets soft capsule content; Described substrate is vegetable oil; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 170

A. get prescription, it is standby with embodiment 7 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 7 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 70%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 5 times of water gagings, soak after 2 hours, adopted steam distillation 4 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 80%, left standstill 30 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 10min, gets volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 40%, volatile oil 0.0I%, substrate 50%, glycerol 0.25%, the soft capsule content of water 1%, 8.74% tween, described substrate are vegetable oil; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 171

A. get prescription, it is standby with embodiment 8 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 3 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 60%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3 times of water gagings, soak after 2 hours, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 2 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 40%, left standstill 12 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 10min, gets volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 5%, volatile oil 5%, substrate 10%, glycerol 1%, the soft capsule content of water 10%, 69% tween, described substrate are vegetable oil; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 172

A. get prescription, it is standby with embodiment 9 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 6 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.05～1.25 in the time of 50～70 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 3.5 times of water gagings, soak after 1.5 hours, adopted steam distillation 2.5 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: the medicinal residues behind the extraction volatile oil such as all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae decoct with water secondary, decoct 1.5 hours at every turn, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 65～70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 40%, left standstill 20 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.05～1.25 in the time of 65～75 ℃, drying gets medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 10min, gets volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 20%, volatile oil 2%, substrate 30%, glycerol 2%, the soft capsule content of water 6%, 40% tween, described substrate are Polyethylene Glycol; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 173

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 10min, gets volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 12.61%, volatile oil 0.14%, substrate 25%, glycerol 1.25%, water 5%, the soft capsule content of tween 56%, described substrate is vegetable oil; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 174

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 10min, gets volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 12.61%, volatile oil 0.14%, substrate 25%, glycerol 1.25%, water 5%, the soft capsule content of tween 56%, described substrate is poly-7 glycol; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 175

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II;

C. the volatile oil that makes is added the Tween 80 mix homogeneously, it is an amount of to add water, with mulser emulsifying 10min, gets volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 12.61%, volatile oil 0.14%, substrate 25%, glycerol 1.25%, water 5%, the soft capsule content of tween 56%, described substrate is vegetable oil, Polyethylene Glycol or the Tween 80 of equivalent; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

Embodiment 176

A. get prescription, it is standby with embodiment 10 to write out a prescription;

B. the extraction of medicated powder I: get Radix Scutellariae and add 4 times of amount alcohol reflux secondaries, each 2.5 hours, concentration of ethanol was 35%, reclaimed ethanol, was concentrated into relative density 1.07～1.15 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae merge together, add 3.5 times of water gagings, soak after 1.5 hours, adopt steam distillation 2.5 hours, collect volatile oil device preservation in addition, and medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.04～1.20 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 45%, left standstill 12 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.14～1.25 in the time of 70 ℃, get medicated powder II;

C. get it filled powder I, medicated powder II add carboxymethyl starch sodium, mix homogeneously, and adding concentration is 20% alcohol granulation, consumption is 30% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add silica gel, mix homogeneously, mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

Claims (7)

1. preparation method for the treatment of cold medicine is characterized in that step is as follows:

A. 72 parts of extracting honeysuckles, 72 parts of Radix Scutellariaes, 72 parts of Herba Schizonepetae, 72 parts of Fructus Gardeniaes, 72 parts of Fructus Forsythiaes, 72 parts of Radix Scrophulariaes, 43 parts of Bombyx Batryticatus, 108 parts of Radix Rehmanniae, 22 parts of Rhizoma Belamcandae, 43 parts of Radix Platycodoniss, 43 parts of Herba Menthaes, 43 parts of Periostracum Cicadaes, 43 parts of Radix Saposhnikoviaes, 22 parts in Radix Glycyrrhizae are standby;

B. the extraction of medicated powder I: get Radix Scutellariae and add 5 times of amount alcohol reflux secondaries, each 2 hours, concentration of ethanol was 65%, reclaimed ethanol, was concentrated into relative density 1.15～1.20 in the time of 55 ℃～60 ℃, and drying gets medicated powder I;

The extraction of medicated powder II: 1. extract volatile oil: four Chinese medicine materials such as extracting honeysuckle, Herba Schizonepetae, Herba Menthae, Radix Saposhnikoviae, merge together, add 4 times of water gagings, soak after 1 hour, adopted steam distillation 3 hours, collect volatile oil device preservation in addition, medicinal residues continue to extract; 2. extract: all the other medical materials and Radix Scutellariae medicinal residues and Flos Lonicerae etc. are extracted the medicinal residues behind the volatile oil, decoct with water secondary, decoct 2 hours for the first time, decoct 1 hour for the second time, and collecting decoction filters, and filtrate is concentrated into relative density 1.06～1.11 in the time of 70 ℃, puts cold; 3. precipitate with ethanol: add ethanol and make and contain the alcohol amount and reach 60%, left standstill 24 hours, filter; 4. reclaim ethanol, be concentrated into relative density 1.16～1.20 in the time of 70 ℃, get medicated powder II; Merge medicated powder I, medicated powder II, be ground into fine powder, add volatile oil, add various conventional adjuvants, make medicament.

2. treat the preparation method of cold medicine according to claim 1, the medicated powder I and the medicated powder II mixing fine powders that make of step b wherein, one or more the combination that adds starch, dextrin, lactose, PVP, carboxymethyl starch sodium adjuvant, mix homogeneously, adding concentration is 8～75% alcohol granulations, and consumption is 4～60% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add one or several combinations in magnesium stearate, silica gel, the Polyethylene Glycol, mix homogeneously, tabletting, coating or coating not promptly get tablet.

3. treat the preparation method of cold medicine according to claim 1, wherein the medicated powder I that makes of step b and medicated powder II mixing fine powders, volatile oil, mix homogeneously, the polyethylene glycol 6000 that adds 1～30 times of amount of medicated powder: Macrogol 4000=1～5: 1～4 mixture, heating dissolves, and adopting a speed is 25～75/min, splashes into liquid Paraffin, or methyl-silicone oil or methyl-silicone oil: liquid Paraffin=1～4: in 1～3 the condensed fluid, promptly get drop pill.

4. treat the preparation method of cold medicine according to claim 1, wherein add starch in the medicated powder I that makes of step b and the medicated powder II mixing fine powders, the weight of starch is medicated powder I and medicated powder II weight sum 0.5～2 times, mix homogeneously, adding concentration is 20～30% alcohol granulations, and consumption is 10%～30% of medicated powder and a supplementary product consumption; With particle drying, spray into volatile oil; Add magnesium stearate, the weight of magnesium stearate is 0.1～2% of medicated powder I and medicated powder II weight sum, and mix homogeneously in the capsule for medicine of packing into, promptly gets capsule.

5. treat the preparation method of cold medicine according to claim 1, one or both the combination that wherein adds soluble starch, cyclodextrin adjuvant in the medicated powder I that makes of step b and the medicated powder II mixing fine powders, the amount of used adjuvant is medicated powder I and medicated powder II weight 0.4～3 times, mix homogeneously, add water and granulate, consumption is 10～30% of medicated powder and a supplementary product consumption, with particle drying, spray into volatile oil, promptly get granule.

6. treat the preparation method of cold medicine according to claim 1, wherein the volatile oil that makes of step b adds the Tween 80 mix homogeneously, and it is an amount of to add water, with mulser emulsifying 10min, volatile oil Emulsion; Get glycerol, substrate, medicated powder I and medicated powder II, mixing with homogenize machine homogenize 30min, adds volatile oil Emulsion mix homogeneously again, with homogenize machine homogenize 30min, make medicated powder 12.61%, volatile oil 0.14%, substrate 25%, glycerol 1.25%, water 5%, the soft capsule content of tween 56%, described substrate is a kind of or combination in any in vegetable oil, Polyethylene Glycol or the Tween 80; Get the foregoing thing and suppress soft capsule with the rotation rolling capsule machine.

7. as the preparation method of treatment cold medicine as described in the claim 6, it is characterized in that vegetable oil in the substrate is the one or any combination in Oleum Brassicae campestris, Oleum Glycines, Oleum Arachidis hypogaeae semen, Oleum Helianthi, Oleum Gossypii semen, Semen Maydis oil, Oleum sesami, olive oil, the safflower oil.