CN1964946A - 作为hsp 70诱导物的2－丙烯－1－酮 - Google Patents

作为hsp 70诱导物的2－丙烯－1－酮 Download PDF

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Publication number
CN1964946A
CN1964946A CNA2005800190202A CN200580019020A CN1964946A CN 1964946 A CN1964946 A CN 1964946A CN A2005800190202 A CNA2005800190202 A CN A2005800190202A CN 200580019020 A CN200580019020 A CN 200580019020A CN 1964946 A CN1964946 A CN 1964946A
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alkyl
phenyl
acryloyl
compound
compound number
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Chinese (zh)
Inventor
P·库马尔
U·R·曼尼
R·C·古普塔
S·S·那卡尼
A·莫汉纳
R·坦登
S·孟希
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Torrent Pharmaceuticals Ltd
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Torrent Pharmaceuticals Ltd
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Publication of CN1964946A publication Critical patent/CN1964946A/zh
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    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
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    • A61P27/06—Antiglaucoma agents or miotics
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
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    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18—Oxygen or sulfur atoms
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    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Neurosurgery (AREA)
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  • Neurology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Communicable Diseases (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
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  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CNA2005800190202A 2004-04-12 2005-04-11 作为hsp 70诱导物的2－丙烯－1－酮 Pending CN1964946A (zh)

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IN178/KOL/2004 2004-04-12
IN178KO2004 2004-04-12

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EP (1) EP1748987A2 (cg-RX-API-DMAC10.html)
JP (1) JP4790704B2 (cg-RX-API-DMAC10.html)
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Cited By (7)

* Cited by examiner, † Cited by third party
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CN105237487A (zh) * 2015-10-19 2016-01-13 安徽中医药大学 含川芎嗪基查尔酮芳氧烷酸类化合物、制备方法及其应用
CN105503745A (zh) * 2016-01-07 2016-04-20 首都师范大学 含4-氧代喹唑啉-2-基的查耳酮类似物及其制备方法和用途
CN108558763A (zh) * 2018-05-16 2018-09-21 辽宁大学 含吲唑的查尔酮类衍生物及其应用
CN108698999A (zh) * 2015-11-20 2018-10-23 李镐允 喹诺酮查尔酮化合物及其用途
CN109620827A (zh) * 2018-12-14 2019-04-16 中国医学科学院医药生物技术研究所 杂环丙烯酮类化合物作为抗菌剂的用途
CN111171018A (zh) * 2018-11-13 2020-05-19 沈阳化工研究院有限公司 一种查尔酮类化合物及其应用
CN114105927A (zh) * 2020-08-31 2022-03-01 湖南超亟检测技术有限责任公司 一种新型苯并吡喃腈类荧光分子探针的构建及其体外诊断应用

Families Citing this family (13)

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CA2562130A1 (en) 2005-10-20
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