CN1947765A - 由板蓝根和射干制成的药物组合物及其制备方法和用途 - Google Patents
由板蓝根和射干制成的药物组合物及其制备方法和用途 Download PDFInfo
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- CN1947765A CN1947765A CN 200610135840 CN200610135840A CN1947765A CN 1947765 A CN1947765 A CN 1947765A CN 200610135840 CN200610135840 CN 200610135840 CN 200610135840 A CN200610135840 A CN 200610135840A CN 1947765 A CN1947765 A CN 1947765A
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Abstract
Description
组别 | 配比 | 给药量(mg/kg) | 肺指数值 | 抑制率(%) |
感染对照组正常对照组板蓝根组射干组 | ---- | --200200 | 1.55±0.201.04±0.131.35±0.17*1.36±0.18* | --12.9012.26 |
板蓝根∶射干 | 1∶0.051∶0.11∶0.21∶0.51∶0.81∶11∶21∶51∶101∶201∶251∶50 | 200200200200200200200200200200200200 | 1.34±0.16*1.20±0.14**1.21±0.15**1.18±0.13**1.19±0.15**1.17±0.13**1.18±0.12**1.23±0.14**1.25±0.17**1.28±0.15**1.30±0.16*1.26±0.15** | 13.5522.5821.9423.8723.2324.5223.8720.6419.3517.4216.1318.71 |
组别 | 配比 | 给药量(mg/kg) | 阳性率(%) | 抑制率(%) |
感染对照组正常对照组板蓝根组射干组 | ---- | --200200 | 45.11±6.8522.32±3.2339.56±5.87*38.97±5.93* | --12.3013.61 |
板蓝根∶射干 | 1∶0.11∶11∶2 | 200200200 | 35.46±5.07**33.14±4.57**28.67±3.78** | 21.3926.5436.44 |
组别 | 配比 | 给药量(mg/kg) | 肿胀度(mg) | 肿胀抑制率(%) |
对照组板蓝根组射干组 | --- | -200200 | 2.39±0.951.82±0.11*1.81±0.10* | -23.8424.26 |
板蓝根∶射干 | 1∶0.11∶11∶2 | 200200200 | 1.54±0.09**1.41±0.10**1.26±0.08** | 35.5641.0047.28 |
菌种 | 组别 | 药品 | 24h生存数 | 24h死亡数 |
绿脓杆菌 | 123456 | 板蓝根注射液射干注射液板蓝根∶射干(1∶0.1)板蓝根∶射干(1∶1)板蓝根∶射干(1∶2)氯化钠注射液 | 78910101 | 321009 |
结核杆菌 | 123456 | 板蓝根注射液射干注射液板蓝根∶射干(1∶0.1)板蓝根∶射干(1∶1)板蓝根∶射干(1∶2)氯化钠注射液 | 98109101 | 120109 |
肺炎双球菌 | 123456 | 板蓝根注射液射干注射液板蓝根∶射干(1∶0.1)板蓝根∶射干(1∶1)板蓝根∶射干(1∶2)氯化钠注射液 | 89910100 | 211*0010 |
金黄色葡萄球菌 | 123456 | 板蓝根注射液射干注射液板蓝根∶射干(1∶0.1)板蓝根∶射干(1∶1)板蓝根∶射干(1∶2)氯化钠注射液 | 881010100 | 2200010 |
组别 | 配比(g+g) | 给药量(mg/kg) | 阳性率(%) | 抑制率(%) |
感染对照组正常对照组板蓝根组射干组 | ---- | --200200 | 42.39±6.2525.32±4.0737.48±5.82*36.95±5.69* | --11.5812.84 |
板蓝根∶射干 | 1∶0.011∶0.021∶0.051∶0.11∶0.51∶11∶21∶101∶251∶501∶1001∶250 | 200200200200200200200200200200200200 | 35.21±5.54**36.95±5.62**35.02±5.43**32.42±5.49**31.25±5.21**31.06±5.16**31.63±5.32**33.26±5.41**35.16±4.98**34.98±4.75**37.21±5.63**36.78±5.28** | 16.94ab17.39ab18.80ab23.52ab26.28ab26.73ab25.38ab21.54ab19.23ab19.51ab17.41ab18.16ab |
组别 | 配比 | 给药量(mg/kg) | 阳性率(%) | 抑制率(%) |
感染对照组正常对照组板蓝根组射干组 | ---- | --200200 | 41.62±6.3223.49±3.6838.25±5.56*37.87±6.02* | --8.109.01 |
板蓝根∶射干 | 1∶0.011∶0.021∶0.051∶0.11∶0.51∶11∶21∶101∶251∶501∶1001∶250 | 200200200200200200200200200200200200 | 36.13±5.47**35.25±4.43**33.14±5.32**32.03±5.16**31.23±4.87**31.05±5.05**31.58±4.96**34.05±5.54**34.01±4.21**34.02±4.32**35.87±4.66**35.69±4.87** | 13.19ab15.31ab20.37ab23.04ab24.96ab25.40ab24.12ab18.19ab18.28ab18.26ab13.82ab14.25ab |
组别 | 配比 | 给药量(mg/kg) | 肺指数值 | 抑制率(%) |
感染对照组正常对照组板蓝根组射干组 | ---- | --200200 | 1.61±0.251.03±0.11*1.48±0.23*1.42±0.21* | --8.0711.80 |
板蓝根∶射干 | 1∶0.051∶0.11∶0.21∶0.51∶0.81∶11∶21∶51∶101∶201∶251∶50 | 200200200200200200200200200200200200 | 1.39±0.22**1.36±0.20**1.31±0.21**1.28±0.18**1.25±0.17**1.24±0.19**1.23±0.17**1.26±0.14**1.32±0.16**1.38±0.14**1.37±0.21**1.35±0.23** | 13.66ab15.53ab18.63ab20.50ab22.36ab22.98ab23.60ab21.74ab18.61ab14.29ab14.91ab16.15ab |
批号 | 总氮含量(%) | 得率(%) |
123 | 13.2514.2820.39 | 1.531.421.35 |
批号 | 总黄酮含量(%) | 得率(%) |
123 | 61.2359.6560.27 | 5.446.376.41 |
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CN103550206A (zh) * | 2013-10-23 | 2014-02-05 | 重庆市中药研究院 | 一种白藜芦醇靛玉红组合药物、缓释微囊剂及其应用 |
CN112826877A (zh) * | 2021-01-19 | 2021-05-25 | 北京理工亘舒科技有限公司 | 一种射干分离物及其制备方法和用途 |
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CN103550206A (zh) * | 2013-10-23 | 2014-02-05 | 重庆市中药研究院 | 一种白藜芦醇靛玉红组合药物、缓释微囊剂及其应用 |
CN103550206B (zh) * | 2013-10-23 | 2015-11-25 | 重庆市中药研究院 | 一种白藜芦醇靛玉红组合药物、缓释微囊剂及其应用 |
CN112826877A (zh) * | 2021-01-19 | 2021-05-25 | 北京理工亘舒科技有限公司 | 一种射干分离物及其制备方法和用途 |
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