CN1947012A - 激动剂抗－trkC抗体和使用其的方法 - Google Patents

激动剂抗－trkC抗体和使用其的方法 Download PDF

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Publication number
CN1947012A
CN1947012A CNA2004800414321A CN200480041432A CN1947012A CN 1947012 A CN1947012 A CN 1947012A CN A2004800414321 A CNA2004800414321 A CN A2004800414321A CN 200480041432 A CN200480041432 A CN 200480041432A CN 1947012 A CN1947012 A CN 1947012A
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CN
China
Prior art keywords
seq
trkc
antibody
xaa
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2004800414321A
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English (en)
Chinese (zh)
Inventor
J·彭斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rinat Neuroscience Corp
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Rinat Neuroscience Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rinat Neuroscience Corp filed Critical Rinat Neuroscience Corp
Publication of CN1947012A publication Critical patent/CN1947012A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CNA2004800414321A 2003-12-23 2004-12-23 激动剂抗－trkC抗体和使用其的方法 Pending CN1947012A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53259203P 2003-12-23 2003-12-23
US60/532,592 2003-12-23

Publications (1)

Publication Number Publication Date
CN1947012A true CN1947012A (zh) 2007-04-11

Family

ID=34738811

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800414321A Pending CN1947012A (zh) 2003-12-23 2004-12-23 激动剂抗－trkC抗体和使用其的方法

Country Status (18)

Country Link
US (2) US7968690B2 (https=)
EP (2) EP1700121A4 (https=)
JP (1) JP4503617B2 (https=)
KR (1) KR20070001932A (https=)
CN (1) CN1947012A (https=)
AP (1) AP2006003670A0 (https=)
AU (1) AU2004308482A1 (https=)
BR (1) BRPI0417270A (https=)
CA (1) CA2551097A1 (https=)
CR (1) CR8525A (https=)
EA (1) EA200601220A1 (https=)
EC (1) ECSP066722A (https=)
IL (1) IL176485A0 (https=)
MA (1) MA28395B1 (https=)
NO (1) NO20063375L (https=)
SG (1) SG166768A1 (https=)
TN (1) TNSN06202A1 (https=)
WO (1) WO2005062955A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120118180A (zh) * 2025-03-13 2025-06-10 中国兽医药品监察所 一种非洲猪瘟病毒p30蛋白单克隆抗体的制备及其应用

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AU2012216702B2 (en) * 2005-08-26 2014-12-04 Roche Glycart Ag Modified antigen binding molecules with altered cell signaling activity
CA2619298C (en) * 2005-08-26 2017-07-04 Glycart Biotechnology Ag Modified antigen binding molecules with altered cell signaling activity
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BR112015010360A8 (pt) * 2012-11-08 2018-01-16 Eleven Biotherapeutics Inc antagonistas de il-6 e utilização dos mesmos.
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CA2982237A1 (en) 2015-06-05 2016-12-08 Novartis Ag Antibodies targeting bone morphogenetic protein 9 (bmp9) and methods therefor
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BR112021003093A2 (pt) * 2018-08-22 2021-05-11 Merck Patent Gmbh tratamento de câncer de mama triplo negativo que visa a inibição de tgf-beta
US11834512B2 (en) 2020-05-04 2023-12-05 The Regents Of The University Of California Inhibiting anti-ENPP1 antibodies
KR20240102971A (ko) 2021-11-16 2024-07-03 제넨테크, 인크. 모수네투주맙을 이용하여 전신 홍반성 루푸스(sle)를 치료하기 위한 방법과 조성물

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN120118180A (zh) * 2025-03-13 2025-06-10 中国兽医药品监察所 一种非洲猪瘟病毒p30蛋白单克隆抗体的制备及其应用

Also Published As

Publication number Publication date
EP2402756A3 (en) 2012-02-22
EP1700121A2 (en) 2006-09-13
NO20063375L (no) 2006-09-18
EA200601220A1 (ru) 2006-12-29
MA28395B1 (fr) 2007-01-02
JP2007519401A (ja) 2007-07-19
IL176485A0 (en) 2006-10-05
US20090202526A1 (en) 2009-08-13
BRPI0417270A (pt) 2007-03-27
CA2551097A1 (en) 2005-07-14
US7968690B2 (en) 2011-06-28
WO2005062955A2 (en) 2005-07-14
CR8525A (es) 2007-05-30
TNSN06202A1 (en) 2007-11-15
KR20070001932A (ko) 2007-01-04
AP2006003670A0 (en) 2006-06-30
JP4503617B2 (ja) 2010-07-14
ECSP066722A (https=) 2006-11-24
US20110281348A1 (en) 2011-11-17
EP2402756A2 (en) 2012-01-04
AU2004308482A1 (en) 2005-07-14
WO2005062955A3 (en) 2006-06-22
SG166768A1 (en) 2010-12-29
EP1700121A4 (en) 2008-09-03

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