KR20070001932A - 작용물질 항 티알케이씨 항체 및 그의 사용 방법 - Google Patents

작용물질 항 티알케이씨 항체 및 그의 사용 방법 Download PDF

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Publication number
KR20070001932A
KR20070001932A KR1020067014886A KR20067014886A KR20070001932A KR 20070001932 A KR20070001932 A KR 20070001932A KR 1020067014886 A KR1020067014886 A KR 1020067014886A KR 20067014886 A KR20067014886 A KR 20067014886A KR 20070001932 A KR20070001932 A KR 20070001932A
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KR
South Korea
Prior art keywords
seq
antibody
trkc
xaa
site
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020067014886A
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English (en)
Korean (ko)
Inventor
자우메 폰즈
Original Assignee
리나트 뉴로사이언스 코퍼레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 리나트 뉴로사이언스 코퍼레이션 filed Critical 리나트 뉴로사이언스 코퍼레이션
Publication of KR20070001932A publication Critical patent/KR20070001932A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020067014886A 2003-12-23 2004-12-23 작용물질 항 티알케이씨 항체 및 그의 사용 방법 Ceased KR20070001932A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53259203P 2003-12-23 2003-12-23
US60/532,592 2003-12-23

Publications (1)

Publication Number Publication Date
KR20070001932A true KR20070001932A (ko) 2007-01-04

Family

ID=34738811

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067014886A Ceased KR20070001932A (ko) 2003-12-23 2004-12-23 작용물질 항 티알케이씨 항체 및 그의 사용 방법

Country Status (18)

Country Link
US (2) US7968690B2 (https=)
EP (2) EP1700121A4 (https=)
JP (1) JP4503617B2 (https=)
KR (1) KR20070001932A (https=)
CN (1) CN1947012A (https=)
AP (1) AP2006003670A0 (https=)
AU (1) AU2004308482A1 (https=)
BR (1) BRPI0417270A (https=)
CA (1) CA2551097A1 (https=)
CR (1) CR8525A (https=)
EA (1) EA200601220A1 (https=)
EC (1) ECSP066722A (https=)
IL (1) IL176485A0 (https=)
MA (1) MA28395B1 (https=)
NO (1) NO20063375L (https=)
SG (1) SG166768A1 (https=)
TN (1) TNSN06202A1 (https=)
WO (1) WO2005062955A2 (https=)

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ES2672640T3 (es) 2003-11-05 2018-06-15 Roche Glycart Ag Moléculas de unión a antígeno con afinidad de unión a receptores Fc y función efectora incrementadas
AU2012216702B2 (en) * 2005-08-26 2014-12-04 Roche Glycart Ag Modified antigen binding molecules with altered cell signaling activity
CA2619298C (en) * 2005-08-26 2017-07-04 Glycart Biotechnology Ag Modified antigen binding molecules with altered cell signaling activity
WO2007125604A1 (ja) 2006-04-28 2007-11-08 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute 神経毒素の定量方法
US10259626B2 (en) 2012-03-08 2019-04-16 Selig Sealing Products, Inc. Container sealing member with protected security component and removal tab
WO2013134365A1 (en) 2012-03-08 2013-09-12 Ludwig Institute For Cancer Research Ltd TGF-β1 SPECIFIC ANTIBODIES AND METHODS AND USES THEREOF
BR112015010360A8 (pt) * 2012-11-08 2018-01-16 Eleven Biotherapeutics Inc antagonistas de il-6 e utilização dos mesmos.
PT3215530T (pt) 2014-11-07 2019-11-21 Sesen Bio Inc Anticorpos de il-6 melhorados
CA2982237A1 (en) 2015-06-05 2016-12-08 Novartis Ag Antibodies targeting bone morphogenetic protein 9 (bmp9) and methods therefor
CA2993645A1 (en) 2015-07-28 2017-02-02 Otonomy, Inc. Trkb or trkc agonist compositions and methods for the treatment of otic conditions
EP3419599A4 (en) 2016-02-23 2019-09-11 Sesen Bio, Inc. IL-6 ANTAGONIST FORMULATIONS AND USE THEREOF
JP7033789B2 (ja) 2016-06-29 2022-03-11 オトノミー，インク． トリグリセリド耳用製剤とその使用
BR112021003093A2 (pt) * 2018-08-22 2021-05-11 Merck Patent Gmbh tratamento de câncer de mama triplo negativo que visa a inibição de tgf-beta
US11834512B2 (en) 2020-05-04 2023-12-05 The Regents Of The University Of California Inhibiting anti-ENPP1 antibodies
KR20240102971A (ko) 2021-11-16 2024-07-03 제넨테크, 인크. 모수네투주맙을 이용하여 전신 홍반성 루푸스(sle)를 치료하기 위한 방법과 조성물
CN120118180B (zh) * 2025-03-13 2025-12-05 中国兽医药品监察所 一种非洲猪瘟病毒p30蛋白单克隆抗体的制备及其应用

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Also Published As

Publication number Publication date
EP2402756A3 (en) 2012-02-22
EP1700121A2 (en) 2006-09-13
NO20063375L (no) 2006-09-18
EA200601220A1 (ru) 2006-12-29
MA28395B1 (fr) 2007-01-02
JP2007519401A (ja) 2007-07-19
IL176485A0 (en) 2006-10-05
US20090202526A1 (en) 2009-08-13
BRPI0417270A (pt) 2007-03-27
CA2551097A1 (en) 2005-07-14
US7968690B2 (en) 2011-06-28
WO2005062955A2 (en) 2005-07-14
CN1947012A (zh) 2007-04-11
CR8525A (es) 2007-05-30
TNSN06202A1 (en) 2007-11-15
AP2006003670A0 (en) 2006-06-30
JP4503617B2 (ja) 2010-07-14
ECSP066722A (https=) 2006-11-24
US20110281348A1 (en) 2011-11-17
EP2402756A2 (en) 2012-01-04
AU2004308482A1 (en) 2005-07-14
WO2005062955A3 (en) 2006-06-22
SG166768A1 (en) 2010-12-29
EP1700121A4 (en) 2008-09-03

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