CN1931295A - Wind dispelling spray and its prepn process - Google Patents

Abstract

The present invention relates to health product, and is especially one kind of wind dispelling spray for remitting pain and its preparation process. The wind dispelling spray is prepared with eight kinds of Chinese medicinal materials, clematis root, ephedra, safflower, achyranthes root, borneol, etc. It is suitable for remitting pain caused by insect bite, cervical spondylosis, scapulohumeral periarthritis, protrusion of lumbar intervertebral disc, osteoarthritis, etc. It is prepared into high pressure spray form for being sprayed directly to the affected part conveniently, and has no toxic side effect.

Description

Wind dispelling spray and preparation method thereof

Technical field

The present invention relates to a kind of health-care products, promptly have lenitive wind dispelling spray and preparation method thereof.

Background technology

In prior art, aged tendency of population becomes clear day by day, and with age growth and life and work pressure, suffers from crowds such as cervical spondylosis, scapulohumeral periarthritis, rheumatism, rheumatoid, neural headache showed increased all the more.Treatment or the like product that plays health-care effect are oral drugs mostly, take the course of treatment and longly avoid again bone maror excitatory, absorb slowly, can cause other disease.Carry inconvenience simultaneously, need water delivery service when taking, is worth higherly, be with unfavorable factor to indivedual crowds.

Summary of the invention

The objective of the invention is to provide a kind of easy to use, outstanding effect wind dispelling spray and preparation method thereof at above-mentioned deficiency.

Technical solution of the present invention is: every 1000ml wind dispelling spray is made by the raw material of following weight: Radix Clematidis 30-40g, and Herba Ephedrae 30-40g, Flos Carthami 25-35g, Cortex Illici difengpi 25-35g passes through muscle 20-30g always, Radix Achyranthis Bidentatae 20-30g, year is seen 20-30g, Borneolum Syntheticum 5-10g.

Preferred component of wind dispelling spray and content are Radix Clematidis 40g, Herba Ephedrae 40g, and Flos Carthami 35g, Cortex Illici difengpi 35g passes through muscle 30g always, Radix Achyranthis Bidentatae 30g, year is seen 30g, Borneolum Syntheticum 10g.

Motherland's Chinese medicine thinks that meridians are important component parts of human tissue structure, and it is to link up the exterior and the interior, get in touch with the unique system of internal organs and operation QI and blood up and down, passages through which vital energy circulates, irons the arteries and veins net, and is unlikely nowhere.Meridians have the four stages in the course of an epidemic febrile disease, link up the exterior and the interior, resist pathogenic factor, safeguard body on physiology function.Body surface extremity microcirculation is not smooth, all with meridians smooth due to.Meridians are unimpeded, and microcirculation then improves, and general rule is not bitterly, and is bitterly then obstructed, so dredge the meridian passage, and microcirculation improvement both can reach anti-inflammatory analgetic, blood circulation promoting and blood stasis dispelling, antiviral effect.This prescription is with dredge the meridian passage, and microcirculation improvement is an aim, gets Radix Clematidis, Herba Ephedrae and is monarch.Radix Clematidis: acrid in the mouth, salty, little hardship, dredge the meridian passage, expelling wind and removing dampness are arranged, improve the effect of blood circulation.Herba Ephedrae: the depressed lung-energy dispersing that induces sweat, diaphoresis, inducing diuresis to remove edema antipyretic effect.With Flos Carthami, Cortex Illici difengpi is minister, and collaborative monarch drug logically irons actively, improves the function of blood microcirculation.Flos Carthami: flat, warm in nature, the GUIXIN of distinguishing the flavor of, Liver Channel.Have that blood stasis dispelling is invigorated blood circulation, the effect of reducing swelling and alleviating pain.See the year: property slightly sweet flavor and flat, effect detoxifcation clearing moist heat.Cortex Illici difengpi: the effect of nature and flavor suffering, hardship, wet, expelling wind and removing dampness promoting the circulation of QI to relieve pain.Pass through muscle always: property is flat, bitter in the mouth, suffering, effect expelling wind and activating blood circulation, kind dispelling the wind and dampness pathogens pain, contracture numbness.Radix Achyranthis Bidentatae: bitter in the mouth, property put down, return liver, kidney to iron function: blood circulation and promoting silt, and bone and muscle strengthening, medicinal is tying-in, then is messenger drug.Borneolum Syntheticum: acrid in the mouth, hardship, cool in nature, GUIXIN, liver, lung meridian.Function: logical all keys, heat clearing away is loose malicious.It is swollen to cure mainly the aphtha tooth, skin ulcer pain infantile malnutrition hemorrhoid, and the gas of fragrance can be kept away all evilnesses, all rheumatism of loosing.Make a general survey of full side, auxilliary mutually association mutually, dredge the meridian passage makes the body microcirculation unimpeded, and the four stages in the course of an epidemic febrile disease is linked up the exterior and the interior, resists pathogenic factor, realizes lenitive effect.

The preparation method of wind dispelling spray may further comprise the steps:

(1) except that Borneolum Syntheticum, get the seven flavor medicine material of above ormal weight, with 75% ethanol with 1: 1.5 ratio merceration 15 days, use 70% alcohol reflux then once, add amount of alcohol and be 4 times of crude drug, refluxing filtered after 2 hours, reclaim ethanol and be concentrated into the clear paste that relative density is 1.22-1.25, adding 95% ethanol is 70% to stir evenly to containing amount of alcohol, leaves standstill filtration in 12 hours, filtrate for later use;

(2) with the Borneolum Syntheticum dissolve with ethanol, standby;

(3) filtrate that obtains in the step (2) is added Borneolum Syntheticum, add 85% ethanol to 1000ml, mixing, promptly.

Health care: alleviating pain.Specifically: 1, anti-inflammatory analgesic: can prevent the synthetic of inflammation-causing substance effectively, by to purification breathing, dredge the meridian passage, the elimination edema of synovial tissue's inflammation, promote the blood circulation at sufferer place, thereby reach the effect of anti-inflammatory analgesic.2, expelling wind and removing dampness: the active drug composition can directly cut off the invasion of the bone toxin at ailing place, removes antigen nanocrystal composition, the urate rheumatism factor effectively, reaches and dispels the osteopathia root, cuts off the curative effect of bone toxin.3, promoting blood circulation and detumescence: wind dispelling spray is an externally applied spray, and the efficacy of a drug focus of going directly has direct active cell, improves circulation, eliminates congestion and moisture content, recovers the blood supply provisions, reaches the purpose of blood circulation promoting and blood stasis dispelling, anti-inflammation detumescence.4, dredge the meridian passage: the active drug composition directly contacts the sufferer that forms because of traumatic injury, rheumatism intrusion etc., reaches the gentle muscle that nourishes blood, softening vertebral articulations, dredging the meridian, makes atrophy muscle and paralysis nerve progressively recover normal function.5, improve symptom: painful, evident in efficacy to each position swelling fiber crops that rheumatism causes, the soft tissue injury at sufferer place is played microcirculation improvement, promoting the circulation of blood pain relieving, strengthens cellular metabolism, improve symptom rapidly, recover body function.

Suitable crowd: be applicable to the pain crowd who causes because of mosquito bite, cervical spondylosis, scapulohumeral periarthritis, prolapse of lumbar intervertebral disc, osteoarthritis, femur head necrosis, traumatic injury, nervous headache, gout, waist and leg ache, arthralgia, rheumatism, rheumatoid, scapulohumeral periarthritis etc. and nervous headache, waist and leg ache etc.

Using method: get this product and be sprayed on sore place and massage, every day three to four times, serious pain, escalated dose number of times in right amount with thing.

Advantage of the present invention is: 1, this product adopts the high-pressure fog dosage form, can be sprayed directly on to the affected part, and rapid-action, effect is more obvious.2, easy to use, safe, have no side effect, cost is low, ordinary people easily bears.3, the method therefor science, simple, paste-forming rate is high.

Below in conjunction with embodiment and test example the present invention is described in further detail.

The specific embodiment

Embodiment 1

Every 1000ml wind dispelling spray is made by the raw material of following weight: Radix Clematidis 40g, and Herba Ephedrae 40g, Flos Carthami 35g, Cortex Illici difengpi 35g passes through muscle 30g always, Radix Achyranthis Bidentatae 30g, year is seen 30g, Borneolum Syntheticum 10g.

Embodiment 2

Every 1000ml wind dispelling spray is made by the raw material of following weight: Radix Clematidis 30g, and Herba Ephedrae 30g, Flos Carthami 25g, Cortex Illici difengpi 25g passes through muscle 20g always, Radix Achyranthis Bidentatae 20g, year is seen 20g, Borneolum Syntheticum 5g.

Embodiment 3

Every 1000ml wind dispelling spray is made by the raw material of following weight: Radix Clematidis 35g, and Herba Ephedrae 35g, Flos Carthami 30g, Cortex Illici difengpi 30g passes through muscle 25g always, Radix Achyranthis Bidentatae 25g, year is seen 25g, Borneolum Syntheticum 7g.

Embodiment 4

The wind dispelling spray preparation method may further comprise the steps:

(1) raw material: Radix Clematidis 40g, Herba Ephedrae 40g, Flos Carthami 35g, Cortex Illici difengpi 35g passes through muscle 30g always, Radix Achyranthis Bidentatae 30g, year is seen 30g, Borneolum Syntheticum 10g.

(2) except that Borneolum Syntheticum, get the seven flavor medicine material of above ormal weight, with 75% ethanol with 1: 1.5 ratio merceration 15 days, use 70% alcohol reflux then once, add amount of alcohol and be 4 times of crude drug, refluxing filtered after 2 hours, reclaim ethanol and be concentrated into the clear paste that relative density is 1.22-1.25 (50-55 ℃ of survey), adding 95% ethanol is 70% to stir evenly to containing amount of alcohol, leaves standstill filtration in 12 hours, filtrate for later use;

(3) with the Borneolum Syntheticum dissolve with ethanol, standby;

(4) filtrate that obtains in the step (2) is added Borneolum Syntheticum, add 85% ethanol to 1000ml, mixing, promptly.

Test example 1

Through monitoring of hygiene inspection center, Jilin Province this product is carried out " test of mice alleviating pain " and show that this product has the effect of " alleviating pain ".

Material and method:

1, tried thing: the sky adds the peace wind dispelling spray.

2, laboratory animal: 30 of the cleaning level ICR male mices that preclinical medicine institute of Jilin University zoopery center provides, production licence number: SCXK-(Ji) 2003-0001.Mouse feed is given birth to the laboratory animal feed factory by Changchun Lvyuan District benefit and is provided, the quality certification number: SCXK-(Ji) 2003-0004.

3, laboratory environment: 20 ℃-22 ℃ of this laboratory animal room temperatures, relative humidity 55%-65%, the laboratory animal environmental facility quality certification number; The lucky moving word 10-1005 that establishes, animal housing's rank is the cleaning level.

4, reagent: acetic acid, the Beijing Chemical Plant produces; YUNNAN BAIYAO DING, Yunnan Paiyao Group Corp., Ltd produces, product batch number 20040902.

5, key instrument: enumerator.

6, dosage: a 0.5g/ mice.

7, experimental technique: adopt mouse writhing method, 30 mices are divided into 3 groups at random, 10 every group.Every mouse peritoneal of blank is injected 0.6% acetic acid 0.1mL/lOg.bw, turn round the body number of times with what counter records gave behind the algogen each mice in the 15min, be subjected to the examination group to be coated with the sky and add the peace wind dispelling spray, the positive controls abdomen gives YUNNAN BAIYAO DING outward, injects acetic acid and writes down the mouse writhing number of times by the method for blank group behind the 30min.Relatively tried the difference of knob and matched group, carried out t check deal with data with the SPSSforwindow10.0 statistical software.

Result of the test:

Be subjected to the examination group to be tried that mouse writhing number of times and matched group have significant difference behind the thing, the result is as follows:

Group	Dosage (g/ only)	Number of animals (only)	Turn round the body number of times
					x±s	The P value
			The blank group is subjected to examination group positive controls	-0.5g/ 0.5g/ only			10 10 10	17.9±3.5 13.0±4.5 12.4±4.2	0.012 0.006

Conclusion: the sky adds the peace wind dispelling spray the effect of the mice of alleviation pain.

Case 1

The birth on the 10th of Piao Yongshun woman JIUYUE in 1963, firmly existing: Tonghua, Jilin Province county Er Mi town Ma Dangwei occupation: as not have.Medical history: I begin to have suffered from nervous headache because be in a bad way can't orthobiosis and work in February, 1986, also go to how home hospital treatment all not have good effect, in April, 2006 through friend continue just used Tonghua to add day peace wind dispelling spray product after the state of an illness take a turn for the better to some extent, after using 4 bottles, headache returns to one's perfect health and the same working and learning with the normal person of energy, thanks and adds the Gospel that sky peace wind dispelling spray brings to me.

Claims (3)

1, a kind of wind dispelling spray is characterized in that every 1000ml wind dispelling spray made by the raw material of following weight: Radix Clematidis 30-40g, and Herba Ephedrae 30-40g, Flos Carthami 25-35g, Cortex Illici difengpi 25-35g passes through muscle 20-30g always, Radix Achyranthis Bidentatae 20-30g, year is seen 20-30g, Borneolum Syntheticum 5-10g.

2, the described wind dispelling spray of claim 1 is characterized in that being: Radix Clematidis 40g, and Herba Ephedrae 40g, Flos Carthami 35g, Cortex Illici difengpi 35g passes through muscle 30g always, Radix Achyranthis Bidentatae 30g, year is seen 30g, Borneolum Syntheticum 10g.

3, a kind of method for preparing claim 1 or 2 described wind dispelling sprays is characterized in that may further comprise the steps:

(1) except that Borneolum Syntheticum, get the seven flavor medicine material of above ormal weight, with 75% ethanol with 1: 1.5 ratio merceration 15 days, use 70% alcohol reflux then once, add amount of alcohol and be 4 times of crude drug, refluxing filtered after 2 hours, reclaim ethanol and be concentrated into the clear paste that relative density is 1.22-1.25, adding 95% ethanol is 70% to stir evenly to containing amount of alcohol, leaves standstill filtration in 12 hours, filtrate for later use;

(2) with the Borneolum Syntheticum dissolve with ethanol, standby;

(3) filtrate that obtains in the step (2) is added Borneolum Syntheticum, add 85% ethanol to 1000ml, mixing, promptly.