CN1922332B - 预测并克服对卵巢癌化疗的抗性的方法及预测结肠癌发生的方法 - Google Patents
预测并克服对卵巢癌化疗的抗性的方法及预测结肠癌发生的方法 Download PDFInfo
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- CN1922332B CN1922332B CN2004800421486A CN200480042148A CN1922332B CN 1922332 B CN1922332 B CN 1922332B CN 2004800421486 A CN2004800421486 A CN 2004800421486A CN 200480042148 A CN200480042148 A CN 200480042148A CN 1922332 B CN1922332 B CN 1922332B
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Plant Pathology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53350503P | 2003-12-31 | 2003-12-31 | |
| US60/533,505 | 2003-12-31 | ||
| PCT/US2004/043837 WO2005066371A2 (en) | 2003-12-31 | 2004-12-30 | Methods for predicting and overcoming resistance to chemotherapy in ovarian cancer and for predicting colon cancer occurrence |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210472073.1A Division CN102989009B (zh) | 2003-12-31 | 2004-12-30 | 预测并克服对卵巢癌化疗的抗性的方法及预测结肠癌发生的方法 |
| CN201110195193.7A Division CN102321584B (zh) | 2003-12-31 | 2004-12-30 | 预测并克服对卵巢癌化疗的抗性的方法及预测结肠癌发生的方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1922332A CN1922332A (zh) | 2007-02-28 |
| CN1922332B true CN1922332B (zh) | 2013-06-12 |
Family
ID=34748910
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2004800421486A Expired - Fee Related CN1922332B (zh) | 2003-12-31 | 2004-12-30 | 预测并克服对卵巢癌化疗的抗性的方法及预测结肠癌发生的方法 |
| CN201110195193.7A Expired - Fee Related CN102321584B (zh) | 2003-12-31 | 2004-12-30 | 预测并克服对卵巢癌化疗的抗性的方法及预测结肠癌发生的方法 |
| CN201210472073.1A Expired - Fee Related CN102989009B (zh) | 2003-12-31 | 2004-12-30 | 预测并克服对卵巢癌化疗的抗性的方法及预测结肠癌发生的方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110195193.7A Expired - Fee Related CN102321584B (zh) | 2003-12-31 | 2004-12-30 | 预测并克服对卵巢癌化疗的抗性的方法及预测结肠癌发生的方法 |
| CN201210472073.1A Expired - Fee Related CN102989009B (zh) | 2003-12-31 | 2004-12-30 | 预测并克服对卵巢癌化疗的抗性的方法及预测结肠癌发生的方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (5) | US7700280B2 (enExample) |
| EP (2) | EP2395112B1 (enExample) |
| JP (3) | JP4682152B2 (enExample) |
| CN (3) | CN1922332B (enExample) |
| ES (1) | ES2394799T3 (enExample) |
| TW (1) | TWI301066B (enExample) |
| WO (1) | WO2005066371A2 (enExample) |
Families Citing this family (45)
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| JP4682152B2 (ja) * | 2003-12-31 | 2011-05-11 | ザ・ペン・ステート・リサーチ・ファンデーション | 卵巣がんの化学療法に対する抵抗性を予測および克服するための方法ならびに結腸がんの発生を予測するための方法 |
| AU2006249235B2 (en) * | 2004-05-14 | 2010-11-11 | Abraxis Bioscience, Llc | Sparc and methods of use thereof |
| US8420603B2 (en) * | 2004-05-14 | 2013-04-16 | Abraxis Bioscience, Llc | SPARC and methods of use thereof |
| EP3327031A1 (en) * | 2004-05-14 | 2018-05-30 | Abraxis BioScience, LLC | Disease site-delivering pharmaceutical compositions comprising paclitaxel |
| US7553496B2 (en) * | 2004-12-21 | 2009-06-30 | University Of Kentucky Research Foundation | VEGF-A as an inhibitor of angiogenesis and methods of using same |
| US8445198B2 (en) | 2005-12-01 | 2013-05-21 | Medical Prognosis Institute | Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy |
| WO2007072225A2 (en) * | 2005-12-01 | 2007-06-28 | Medical Prognosis Institute | Methods and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy |
| ES2432759T3 (es) * | 2006-06-13 | 2013-12-05 | The Rockefeller University | Nuevos métodos de diagnóstico |
| DE102006035393A1 (de) * | 2006-11-02 | 2008-05-15 | Signature Diagnostics Ag | Prognostische Marker für die Klassifizierung des dreijährigen progessionsfreien Überlebens von Patienten mit Kolonkarzinomen basierend auf Expressionsprofilen von biologischen Proben |
| US20110178154A1 (en) * | 2007-02-06 | 2011-07-21 | Birrer Michael J | gene expression profile that predicts ovarian cancer subject response to chemotherapy |
| WO2008109519A2 (en) * | 2007-03-02 | 2008-09-12 | University Of South Florida | Micro-rna profiles associated with endometrial cancer development and response to cisplatin and doxorubicin chemotherapy |
| KR20100065189A (ko) | 2007-09-11 | 2010-06-15 | 유니버시티 오브 매사추세츠 | 암을 치료하기 위한 인슐린유사 성장 인자 결합 단백질 7 |
| BRPI0906573A2 (pt) * | 2008-01-31 | 2015-07-07 | Univ Keio | Método para determinação da sensibilidade para agentes anticâncer |
| US8093000B2 (en) * | 2008-05-09 | 2012-01-10 | The Regents Of The University Of California | Methods for predicting and treating tumors resistant to drug, immunotherapy, and radiation |
| WO2010135786A1 (en) * | 2009-05-29 | 2010-12-02 | Clinical Genomics Pty. Ltd. | A method for diagnosing neoplasms and molecules for use therein |
| CA2767621A1 (en) * | 2009-07-09 | 2011-01-13 | Abraxis Bioscience, Llc | Sparc antisense compositions and uses thereof |
| DK177532B1 (en) | 2009-09-17 | 2013-09-08 | Bio Bedst Aps | Medical use of sPLA2 hydrolysable liposomes |
| US20120245089A1 (en) * | 2009-09-18 | 2012-09-27 | Abraxis Bioscience, Llc | Use of the sparc microenvironment signature in the treatment of cancer |
| EP3081941B1 (en) * | 2009-10-30 | 2018-06-27 | Keio University | Method for determination of sensitivity to anti-cancer agent |
| WO2011135459A2 (en) | 2010-04-29 | 2011-11-03 | Medical Prognosis Institute A/S | Methods and devices for predicting treatment efficacy |
| EP3858385B1 (en) | 2010-05-25 | 2024-09-11 | Syndevrx, Inc. | Polymer-conjugated metap2 inhibitors, and therapeutic methods of use thereof |
| MX2012013874A (es) | 2010-06-03 | 2013-01-24 | Abraxis Bioscience Llc | Uso de la signatura en el microentorno de sparc en el tratamiento de cancer. |
| WO2012110425A1 (en) * | 2011-02-14 | 2012-08-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for monitoring the response to treatment and for treating colorectal cancer |
| EA201691257A1 (ru) | 2011-06-02 | 2017-02-28 | Олмак Дайэгностикс Лимитед | Молекулярно-диагностический тест на рак |
| US9409978B2 (en) * | 2011-09-09 | 2016-08-09 | University Of Massachusetts | Modulation of midbody derivatives |
| HK1214633A1 (zh) | 2012-12-03 | 2016-07-29 | Almac Diagnostics Limited | 癌症的分子诊断测试 |
| MX371095B (es) | 2013-04-10 | 2020-01-16 | Syndevrx Inc | Inhibidores de metionina aminopeptidasa-2 y metodos de tratamiento de la obesidad. |
| GB201409479D0 (en) | 2014-05-28 | 2014-07-09 | Almac Diagnostics Ltd | Molecular diagnostic test for cancer |
| CN103893763B (zh) * | 2014-04-10 | 2016-05-11 | 武汉大学 | Vinexin-β基因在心肌梗死中的应用 |
| CA2955914C (en) * | 2014-07-21 | 2022-09-06 | Ignacio Canals Almazan | Tungsten (vi) salts for use thereof in the treatment of infertility, for favoring normal reproduction and fertility in a non-diabetic female mammal, as well as for improving the efficacy of assisted reproductive techniques |
| US10570457B2 (en) | 2014-09-26 | 2020-02-25 | Medical Prognosis Institute A/S | Methods for predicting drug responsiveness |
| CN108290853B (zh) | 2015-12-10 | 2022-05-31 | 辛德弗雷克斯公司 | 烟曲霉醇衍生物及其多晶型物 |
| CA3008960C (en) | 2016-01-11 | 2024-07-02 | Syndevrx, Inc. | TREATMENT OF TUMORS INDUCED BY METABOLIC DYSFUNCTION |
| US9725769B1 (en) | 2016-10-07 | 2017-08-08 | Oncology Venture ApS | Methods for predicting drug responsiveness in cancer patients |
| AU2017258901A1 (en) | 2016-12-30 | 2018-07-19 | Allarity Therapeutics Europe ApS | Methods for predicting drug responsiveness in cancer patients |
| EP3714896A4 (en) * | 2017-11-21 | 2021-08-04 | Miwa, Naofumi | HUMAN CANCER CELL METASTASIS INHIBITOR AND HUMAN CANCER CELL DETERMINATION AGENT |
| CN113196055B (zh) | 2018-10-15 | 2025-06-27 | 马克斯·普朗克科学促进协会 | 用于治疗疾病的化合物及其筛选方法 |
| EP3870231A1 (en) | 2018-10-26 | 2021-09-01 | Syndevrx, Inc. | Biomarkers of metap2 inhibitors and applications thereof |
| WO2020163795A1 (en) | 2019-02-08 | 2020-08-13 | Dewpoint Therapeutics, Inc. | Methods of characterizing condensate-associated characteristics of compounds and uses thereof |
| AU2020274530A1 (en) * | 2019-05-15 | 2021-12-16 | Whitehead Institute For Biomedical Research | Methods of characterizing and utilizing agent-condensate interactions |
| CN110331203B (zh) * | 2019-07-30 | 2023-04-18 | 中南大学湘雅三医院 | 泛素连接酶chaf1b作为靶位点在制备肺腺癌顺铂增敏药物中的应用 |
| CN114729941A (zh) | 2019-09-18 | 2022-07-08 | 露点治疗公司 | 筛选凝聚物相关特异性的方法及其用途 |
| EP4329778A4 (en) * | 2021-04-26 | 2025-02-19 | Crititech, Inc. | CISPLATIN PARTICLES AND THEIR USES |
| US20250304625A1 (en) * | 2022-04-06 | 2025-10-02 | Vanderbilt University | Articles and methods for inhibiting methionine aminopeptidase activity |
| WO2025057928A1 (ja) * | 2023-09-11 | 2025-03-20 | 国立大学法人大阪大学 | 細胞外小胞内rna修飾による卵巣癌プラチナ製剤抵抗性を判別するための検査方法 |
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| US5624803A (en) | 1993-10-14 | 1997-04-29 | The Regents Of The University Of California | In vivo oligonucleotide generator, and methods of testing the binding affinity of triplex forming oligonucleotides derived therefrom |
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| US6146886A (en) | 1994-08-19 | 2000-11-14 | Ribozyme Pharmaceuticals, Inc. | RNA polymerase III-based expression of therapeutic RNAs |
| CA2207593A1 (en) | 1994-12-13 | 1996-06-20 | John Gustofson | Method and reagent for treatment of arthritic conditions, induction of graft tolerance and reversal of immune responses |
| US6395713B1 (en) | 1997-07-23 | 2002-05-28 | Ribozyme Pharmaceuticals, Inc. | Compositions for the delivery of negatively charged molecules |
| JP2001510808A (ja) | 1997-07-24 | 2001-08-07 | イネックス ファーマシューティカルズ コーポレイション | 核酸触媒の供給のためのリポソーム組成物 |
| AR013269A1 (es) | 1997-08-04 | 2000-12-13 | Scras | Producto que contiene por lo menos un rna de doble filamento combinado con por lo menos un agente anti-viral, para la utilizacion terapeutica en eltratamiento de una enfermedad viral, en especial de la hepatitis viral |
| WO1999031262A2 (en) | 1997-12-16 | 1999-06-24 | Valentis, Inc. | Needle-free injection of formulated nucleic acid molecules |
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| DE19956568A1 (de) | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
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| AU2001253140A1 (en) * | 2000-04-03 | 2001-10-15 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Tumor markers in ovarian cancer |
| CA2418320A1 (en) * | 2000-08-11 | 2002-02-21 | City Of Hope | The anti-neoplastic agent et-743 inhibits trans activation by sxr |
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| AU2000280389A1 (en) | 2001-11-02 | 2003-05-19 | Dana-Farber Cancer Institute | Methods and compositions for the diagnosis of cancer susceptibilities and defective dna repair mechanisms and treatment thereof |
| WO2003045323A2 (en) * | 2001-11-28 | 2003-06-05 | Mediomics, Llc | Anti-angiogenesis methods, compositions and uses therefor |
| AU2003225851A1 (en) * | 2002-03-15 | 2003-09-29 | The Texas A&M University System | Strong gene sets for glioma classification |
| US20040097452A1 (en) * | 2002-11-19 | 2004-05-20 | Isis Pharmaceuticals Inc. | Modulation of kallikrein 6 expression |
| JP4682152B2 (ja) * | 2003-12-31 | 2011-05-11 | ザ・ペン・ステート・リサーチ・ファンデーション | 卵巣がんの化学療法に対する抵抗性を予測および克服するための方法ならびに結腸がんの発生を予測するための方法 |
| WO2006044017A2 (en) * | 2004-08-13 | 2006-04-27 | Jaguar Bioscience Inc. | Systems and methods for identifying diagnostic indicators |
-
2004
- 2004-12-30 JP JP2006547537A patent/JP4682152B2/ja not_active Expired - Fee Related
- 2004-12-30 CN CN2004800421486A patent/CN1922332B/zh not_active Expired - Fee Related
- 2004-12-30 WO PCT/US2004/043837 patent/WO2005066371A2/en not_active Ceased
- 2004-12-30 ES ES04815833T patent/ES2394799T3/es not_active Expired - Lifetime
- 2004-12-30 US US11/026,734 patent/US7700280B2/en not_active Expired - Lifetime
- 2004-12-30 EP EP11163049.7A patent/EP2395112B1/en not_active Expired - Lifetime
- 2004-12-30 CN CN201110195193.7A patent/CN102321584B/zh not_active Expired - Fee Related
- 2004-12-30 EP EP04815833A patent/EP1704250B1/en not_active Expired - Lifetime
- 2004-12-30 CN CN201210472073.1A patent/CN102989009B/zh not_active Expired - Fee Related
- 2004-12-31 TW TW093141829A patent/TWI301066B/zh not_active IP Right Cessation
-
2010
- 2010-02-23 US US12/711,056 patent/US20100221730A1/en not_active Abandoned
- 2010-02-23 US US12/711,036 patent/US20100221729A1/en not_active Abandoned
- 2010-02-23 US US12/711,068 patent/US8192935B2/en not_active Expired - Fee Related
- 2010-03-31 JP JP2010081265A patent/JP5285012B2/ja not_active Expired - Fee Related
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2012
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2016
- 2016-02-24 US US15/052,422 patent/US20160348180A1/en not_active Abandoned
Non-Patent Citations (1)
| Title |
|---|
| MOLER E J.Analysis of molecular profile data using generative anddiscriminative methods.PHYSIOLOGICAL GENOMICS4.2001,4109-126. * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005066371A3 (en) | 2006-04-20 |
| US20100221731A1 (en) | 2010-09-02 |
| US20100221730A1 (en) | 2010-09-02 |
| US20160348180A1 (en) | 2016-12-01 |
| US20050176669A1 (en) | 2005-08-11 |
| JP2007517058A (ja) | 2007-06-28 |
| US7700280B2 (en) | 2010-04-20 |
| CN102321584A (zh) | 2012-01-18 |
| CN102989009A (zh) | 2013-03-27 |
| US8192935B2 (en) | 2012-06-05 |
| US20100221729A1 (en) | 2010-09-02 |
| JP5789591B2 (ja) | 2015-10-07 |
| JP5285012B2 (ja) | 2013-09-11 |
| JP4682152B2 (ja) | 2011-05-11 |
| CN102989009B (zh) | 2015-06-03 |
| JP2013079261A (ja) | 2013-05-02 |
| EP1704250B1 (en) | 2012-09-19 |
| WO2005066371A2 (en) | 2005-07-21 |
| EP1704250A2 (en) | 2006-09-27 |
| JP2010209076A (ja) | 2010-09-24 |
| ES2394799T3 (es) | 2013-02-05 |
| TWI301066B (en) | 2008-09-21 |
| CN1922332A (zh) | 2007-02-28 |
| EP2395112B1 (en) | 2017-02-15 |
| EP2395112A1 (en) | 2011-12-14 |
| CN102321584B (zh) | 2014-01-08 |
| TW200531682A (en) | 2005-10-01 |
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