CN1902311A - 具有n－末端游离硫羟基的新的重组蛋白 - Google Patents

具有n－末端游离硫羟基的新的重组蛋白 Download PDF

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Publication number
CN1902311A
CN1902311A CNA2004800396501A CN200480039650A CN1902311A CN 1902311 A CN1902311 A CN 1902311A CN A2004800396501 A CNA2004800396501 A CN A2004800396501A CN 200480039650 A CN200480039650 A CN 200480039650A CN 1902311 A CN1902311 A CN 1902311A
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CN
China
Prior art keywords
erythropoietin
epo
cys
leu
sequence
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Pending
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CNA2004800396501A
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English (en)
Chinese (zh)
Inventor
C·普尔
J·米尔斯
M·昆宁哈姆
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Janssen Biotech Inc
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Centocor Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
CNA2004800396501A 2003-12-31 2004-12-23 具有n－末端游离硫羟基的新的重组蛋白 Pending CN1902311A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53361703P 2003-12-31 2003-12-31
US60/533,617 2003-12-31

Publications (1)

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CN1902311A true CN1902311A (zh) 2007-01-24

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CNA2004800396501A Pending CN1902311A (zh) 2003-12-31 2004-12-23 具有n－末端游离硫羟基的新的重组蛋白

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US (2) US20050170457A1 (enExample)
EP (1) EP1699920A4 (enExample)
JP (1) JP2008500275A (enExample)
CN (1) CN1902311A (enExample)
AU (1) AU2004311796A1 (enExample)
CA (1) CA2551131A1 (enExample)
WO (1) WO2005065239A2 (enExample)

Cited By (2)

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CN112118847A (zh) * 2018-03-02 2020-12-22 伊莱西奥治疗有限公司 包含突变kras序列和脂质的化合物及其用途

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CN112118847A (zh) * 2018-03-02 2020-12-22 伊莱西奥治疗有限公司 包含突变kras序列和脂质的化合物及其用途
CN112118847B (zh) * 2018-03-02 2024-05-28 伊莱西奥治疗有限公司 包含突变kras序列和脂质的化合物及其用途
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EP1699920A4 (en) 2008-05-28
WO2005065239A3 (en) 2005-11-24
JP2008500275A (ja) 2008-01-10
US20050170457A1 (en) 2005-08-04
WO2005065239A2 (en) 2005-07-21
US20090239790A1 (en) 2009-09-24
CA2551131A1 (en) 2005-07-21
EP1699920A2 (en) 2006-09-13
WO2005065239A8 (en) 2006-08-17
AU2004311796A1 (en) 2005-07-21

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