CN1897882A - 降低烟草使用频率的方法和装置 - Google Patents

降低烟草使用频率的方法和装置 Download PDF

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Publication number
CN1897882A
CN1897882A CNA2004800390666A CN200480039066A CN1897882A CN 1897882 A CN1897882 A CN 1897882A CN A2004800390666 A CNA2004800390666 A CN A2004800390666A CN 200480039066 A CN200480039066 A CN 200480039066A CN 1897882 A CN1897882 A CN 1897882A
Authority
CN
China
Prior art keywords
nicotine
coating
drug
microprojections
microprojection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2004800390666A
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English (en)
Chinese (zh)
Inventor
M·J·N·科尔米尔
R·M·盖尔
A·G·斯科特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of CN1897882A publication Critical patent/CN1897882A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CNA2004800390666A 2003-10-28 2004-10-21 降低烟草使用频率的方法和装置 Pending CN1897882A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51539603P 2003-10-28 2003-10-28
US60/515,396 2003-10-28

Publications (1)

Publication Number Publication Date
CN1897882A true CN1897882A (zh) 2007-01-17

Family

ID=34572833

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800390666A Pending CN1897882A (zh) 2003-10-28 2004-10-21 降低烟草使用频率的方法和装置

Country Status (11)

Country Link
US (1) US7455654B2 (enExample)
EP (1) EP1677688A4 (enExample)
JP (1) JP2007509705A (enExample)
KR (1) KR20060120156A (enExample)
CN (1) CN1897882A (enExample)
AR (1) AR046608A1 (enExample)
AU (1) AU2004287412A1 (enExample)
BR (1) BRPI0415986A (enExample)
CA (1) CA2543154A1 (enExample)
TW (1) TW200605929A (enExample)
WO (1) WO2005044139A2 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
AU2005306422A1 (en) 2004-11-18 2006-05-26 3M Innovative Properties Company Low-profile microneedle array applicator
CN101384297A (zh) * 2005-12-21 2009-03-11 史密丝克莱恩比彻姆公司 烟碱盐的离子电渗透皮投递
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
JP4265696B2 (ja) 2006-07-04 2009-05-20 凸版印刷株式会社 マイクロニードルの製造方法
GB0725018D0 (en) 2007-12-21 2008-01-30 Univ Cardiff Monitoring system for microneedle delivery
GB0725017D0 (en) * 2007-12-21 2008-01-30 Univ Cardiff Aerosol coating of microneedles
AU2008341030B2 (en) 2007-12-24 2014-04-17 Vaxxas Pty Limited Coating method
EP2294415A4 (en) * 2008-05-23 2011-10-05 Univ Queensland DETECTION OF SUBSTANCES TO BE ANALYZED BY A MICRO-NEEDLE STAMPER WITH SELECTIVE REAGENTS
US20100286600A1 (en) * 2009-05-08 2010-11-11 Bommannan D Bommi Transdermal patch device
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
US9943673B2 (en) 2010-07-14 2018-04-17 Vaxxas Pty Limited Patch applying apparatus
WO2013053022A1 (en) * 2011-10-12 2013-04-18 The University Of Queensland Delivery device
CN104703651A (zh) 2012-05-01 2015-06-10 高等教育联邦系统-匹兹堡大学 用于经皮插入的尖端负载的微针阵列
JP6570521B2 (ja) 2013-08-01 2019-09-04 ディグニファイ セラピューティクス エルエルシー 排尿及び排便を誘発するための組成物及び方法
USD726316S1 (en) * 2013-10-23 2015-04-07 Claire A. Marquez Micro-needling tattoo head
CA2975275C (en) 2015-02-02 2023-08-29 Vaxxas Pty Limited Microprojection array applicator and method
WO2016149673A1 (en) 2015-03-18 2016-09-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Bioactive components conjugated to substrates of microneedle arrays
WO2017045031A1 (en) 2015-09-18 2017-03-23 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
US20180264244A1 (en) 2015-09-28 2018-09-20 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
WO2017066768A1 (en) 2015-10-16 2017-04-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices
US11744889B2 (en) 2016-01-05 2023-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
AU2018241251B2 (en) 2017-03-31 2024-06-27 Vaxxas Pty Limited Device and method for coating surfaces
US11175128B2 (en) 2017-06-13 2021-11-16 Vaxxas Pty Limited Quality control of substrate coatings
EP3661587B1 (en) 2017-08-04 2024-10-23 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (map)
JP2022532215A (ja) 2019-05-16 2022-07-13 ユニバーシティ オブ ピッツバーグ － オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 皮膚および非皮膚薬物送達のためのアンダーカット特徴を有するマイクロニードルアレイ
AU2021265743A1 (en) 2020-04-28 2022-11-03 Ticona Llc Microneedle assembly

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) 1964-09-08 Means for vaccinating
US3136314A (en) 1960-08-01 1964-06-09 Kravitz Harvey Vaccinating devices
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) 1972-02-14 1973-08-13 Ici Ltd Pansements
OA05448A (fr) 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
FR2474856A1 (fr) 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
SE8904296D0 (sv) * 1989-12-21 1989-12-21 Pharmacia Ab Transdermal system
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
TW261531B (enExample) * 1993-10-28 1995-11-01 Dynagen Inc
JP3541894B2 (ja) * 1994-02-18 2004-07-14 日本化薬株式会社 温度応答型ハイドロゲル
US5487726A (en) 1994-06-16 1996-01-30 Ryder International Corporation Vaccine applicator system
EP0796128B1 (de) 1994-12-09 1999-03-10 Novartis AG Transdermales system
AU5869796A (en) * 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
ZA975326B (en) 1996-06-18 1998-01-14 Alza Corp Device and method for enhancing transdermal flux of agents being delivered or sampled.
CA2259437C (en) 1996-07-03 2006-12-05 Altea Technologies, Inc. Multiple mechanical microporation of skin or mucosa
US5916524A (en) 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
US5738728A (en) 1996-07-26 1998-04-14 Bio Dot, Inc. Precision metered aerosol dispensing apparatus
US5741554A (en) 1996-07-26 1998-04-21 Bio Dot, Inc. Method of dispensing a liquid reagent
US5743960A (en) 1996-07-26 1998-04-28 Bio-Dot, Inc. Precision metered solenoid valve dispenser
CA2265906C (en) 1996-09-17 2003-11-11 Deka Products Limited Partnership System for delivery of drugs by transport
WO1998028037A1 (en) 1996-12-20 1998-07-02 Alza Corporation Device and method for enhancing transdermal agent flux
DE19654391A1 (de) 1996-12-27 1998-07-02 Basf Ag Katalysator zur selektiven Herstellung von Propylen aus Propan
BR9714113A (pt) 1996-12-31 2000-03-21 Shell Int Research Plataforma de tirante
JP3790338B2 (ja) * 1997-09-18 2006-06-28 帝人株式会社 ポリエーテルエステル型温度応答性ハイドロゲル
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
ATE221400T1 (de) 1997-12-11 2002-08-15 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
EP1037686B1 (en) 1997-12-11 2005-08-17 Alza Corporation Device for enhancing transdermal agent flux
WO1999029298A2 (en) 1997-12-11 1999-06-17 Alza Corporation Device for enhancing transdermal agent flux
US6091975A (en) 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
CA2330207C (en) 1998-06-10 2005-08-30 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
DE69921489T2 (de) * 1998-08-31 2005-10-27 Johnson & Johnson Consumer Companies, Inc. Elektrotransportvorrichtung mit klingen
DE19847715A1 (de) * 1998-10-16 2000-04-20 Lohmann Therapie Syst Lts Verfahren zur Behandlung der Schizophrenie sowie Mittel zur Verwendung in diesem Verfahren
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
ATE416692T1 (de) * 2000-10-13 2008-12-15 Alza Corp Mikronadelelementhalter für schlagapplikator
ATE428357T1 (de) 2000-10-13 2009-05-15 Alza Corp Vorrichtung und verfahren zum durchstechen der haut mit micronadeln
AU9682701A (en) 2000-10-13 2002-04-22 Alza Corp Microblade array impact applicator
ATE428466T1 (de) 2000-10-26 2009-05-15 Alza Corp Transdermales arzneistoffverabreichungssytem mit beschichteten mikrovorsprüngen
US6855372B2 (en) 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections
DE60233939D1 (de) * 2001-04-20 2009-11-19 Alza Corp Mikroprojektionsanordnung mit einem überzug, der ein vorteilhaftes mittel enthält
WO2003048031A2 (en) 2001-11-30 2003-06-12 Alza Corporation Methods and apparatuses for forming microprojection arrays
WO2003053258A1 (en) 2001-12-20 2003-07-03 Alza Corporation Skin-piercing microprojections having piercing depth control
KR20050054483A (ko) * 2002-06-28 2005-06-10 알자 코포레이션 코팅된 미세돌출부를 갖는 경피용 약물 전달 장치
AR042815A1 (es) 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
BRPI0412029A (pt) 2003-06-30 2006-09-05 Alza Corp formulações para microprojeções revestidas contendo contra-ìons não-voláteis
EP1677687A4 (en) 2003-10-28 2008-09-17 Alza Corp ADMINISTRATION OF POLYMERIC CONJUGATES OF PEPTIDES AND THERAPEUTIC PROTEINS THROUGH COATED MICROPROTUBERANCES
US7097631B2 (en) 2003-10-31 2006-08-29 Alza Corporation Self-actuating applicator for microprojection array
CN100548228C (zh) 2003-11-13 2009-10-14 阿尔扎公司 用于透皮递送的组合物和装置

Also Published As

Publication number Publication date
JP2007509705A (ja) 2007-04-19
BRPI0415986A (pt) 2007-01-23
US20050089553A1 (en) 2005-04-28
AR046608A1 (es) 2005-12-14
TW200605929A (en) 2006-02-16
WO2005044139A3 (en) 2005-11-17
WO2005044139A2 (en) 2005-05-19
CA2543154A1 (en) 2005-05-19
KR20060120156A (ko) 2006-11-24
AU2004287412A1 (en) 2005-05-19
EP1677688A2 (en) 2006-07-12
US7455654B2 (en) 2008-11-25
EP1677688A4 (en) 2008-06-04

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication