CN1891233A - Peptide nutrient liquid - Google Patents
Peptide nutrient liquid Download PDFInfo
- Publication number
- CN1891233A CN1891233A CNA2005100441024A CN200510044102A CN1891233A CN 1891233 A CN1891233 A CN 1891233A CN A2005100441024 A CNA2005100441024 A CN A2005100441024A CN 200510044102 A CN200510044102 A CN 200510044102A CN 1891233 A CN1891233 A CN 1891233A
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- CN
- China
- Prior art keywords
- scorpion venom
- peptide
- dry powder
- buthotoxin polypeptide
- nutrient liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to a polypeoptide nutrient liquor and its preparation method. Said method includes the following steps: (1), extracting scorpion venom fluid, freeze-drying to obtain freeze-dried scorpion venom powder; (2), adding distilled water to dilute the freeze-dried scorpion venom powder, high-speed centrifugalization to extract scorpion venom polypeptide, freeze-drying to obtain scorpion venom polypeptide dried powder; and (3), making the scorpion venom polypeptide into oral solution or nutrient liquor for raising immunity of human body, reducing blood-lipid and reducing blood pressure.
Description
Technical field
The present invention relates to a kind of nutritional solution, particularly is the nutritional solution of main component with the Buthotoxin polypeptide.
Background technology
Be subjected to irregular, nutrition unbalanced of the influence of environmental pollution and life, the patient who is called as modern civilization disease or disease of life-style is more and more, and particularly body immunity reduces, and high fat of blood is having a strong impact on the healthy of people.In traditional Chinese medicine, Scorpio has long medicinal history, and scorpion venom is the main component of Scorpio pharmacological action, has been used for treatment of diseases.The main active of scorpion venom is a protein, exists with the scorpion venom protein mixture, and quality is stable inadequately, and activity is lower, affects its therapeutic effect.
Summary of the invention
Technical problem to be solved by this invention provides a kind of peptide nutrient liquid, is active component with the Buthotoxin polypeptide, is used to promote body immunity and blood fat reducing.
Peptide nutrient liquid of the present invention is characterized in that preparing in accordance with the following methods: (1) extracts scorpion venom, and lyophilization obtains the scorpion venom lyophilized powder; (2) with the dilution of scorpion venom lyophilized powder adding distil water, high speed centrifugation extracts Buthotoxin polypeptide, and lyophilization gets Buthotoxin polypeptide dry powder; (3) Buthotoxin polypeptide dry powder is made nutritional solution.
The extraction of scorpion venom according to the variety of way of prior art all can, the scorpion venom lyophilization is kept its activity, the lyophilization temperature is-45 ℃～-80 ℃.
Dissolve with 500～1000ml distilled water diluting according to 10 gram scorpion venom lyophilized powders, at centrifugal rotational speed is under 10000～15000r/min, centrifugal 10～20min, get supernatant and successively use the filtering with microporous membrane of 0.45 μ m and 0.22 μ m, with the lyophilizing of gained filtrate (temperature-45 ℃～-80 ℃), obtain Buthotoxin polypeptide dry powder.
The nutritional solution that the present invention makes can be to give birth to peptide oral liquid or give birth to peptide nutritious wine.
The preparation of giving birth to peptide oral liquid is to add Buthotoxin polypeptide dry powder 1～100mg in the 100ml water, adds flavoring agent Mel 0.1～25g then.
The preparation of giving birth to peptide nutritious wine is to add Buthotoxin polypeptide dry powder 1～100mg immersion in 28 °～42 ° Chinese liquor of 100ml to form.
The present invention has the effect of blood fat reducing, blood pressure lowering, slow down aging and lifting body immunity.
Clinical trial:
(1) experimenter group's 33 examples, women's 9 examples wherein, male's 24 examples, 41.3 years old mean age, T-CHOL is at 6.5～10.8mmol/l, triglyceride 2.8～4.6mmol/l.
Take living peptide oral liquid, one of every day (10ml) in the week, be increased to 2 of every days second week.
After taking one month, have 21 examples to drop to normal value, 9 examples are near normal value, and 2 examples descend to some extent, and 1 example is not obvious.And patient feels energetically, not easy catching a cold during taking.
(2) experimenter group's 35 examples are the male, and 49 years old mean age, T-CHOL is at 6.5～10.8mmol/l, triglyceride 2.8～4.6mmol/l.
Take living peptide nutritious wine, every day 50～150ml.
After taking one month, have 27 examples to drop to normal value, 6 examples are near normal value, and 2 examples are not obvious.And patient feels energetically, not easy catching a cold during taking.
(3) experimenter group: 31 examples, male's 17 examples wherein, women's 14 examples, 72 years old mean age, T-CHOL 7.8～12.5mmol/L, triglyceride 2.5～4.3mmol/L.
Take living peptide oral liquid, one of every day (10ml) in the week, be increased to 2 of every days second week.
After taking one month, have 26 examples to drop to normal value, 3 examples are near normal value, and 1 example descends to some extent, and 1 example is not obvious.
(4) improve immunity, resisting fatigue, slow down aging
Experimenter group: 38 people, male 33 people wherein, women 5 people, 64.7 years old mean age.Symptom is lassitude, and is weak, easy catching a cold, and pachylosis, constipation, the stench of passwinding, the length of one's sleep is short, emotional instability.
Take living peptide nutritious wine, every day 50～150ml.
After 2 months: in high spirits, in a good humor, to walk energetically, defecation is normal, and the length of one's sleep is elongated, has no interest, and it is glossy that skin becomes, and seems young.
The specific embodiment
Embodiment one:
Scorpion venom-50 ℃ of following lyophilizations, is obtained the scorpion venom lyophilized powder; Get 10g scorpion venom lyophilized powder and add the 1000ml distilled water diluting, high speed centrifugation 15min under 10000r/min gets the filtering with microporous membrane that supernatant is successively used 0.45 μ m and 0.22 μ m, with the lyophilizing of gained filtrate (temperature-50 ℃), obtains Buthotoxin polypeptide dry powder; Getting 50mg Buthotoxin polypeptide dry powder joins and adds Mel 10g in the 100ml distilled water again and mix well and make nutritional solution.
Embodiment two:
Scorpion venom-60 ℃ of following lyophilizations, is obtained the scorpion venom lyophilized powder; Get 10g scorpion venom lyophilized powder and add the 800ml distilled water diluting, high speed centrifugation 10min under 13000r/min gets the filtering with microporous membrane that supernatant is successively used 0.45 μ m and 0.22 μ m, with the lyophilizing of gained filtrate (temperature-60 ℃), obtains Buthotoxin polypeptide dry powder; Getting 100mg Buthotoxin polypeptide dry powder joins and adds Mel 25g in the 100ml distilled water again and mix well and make nutritional solution.
Embodiment three:
Scorpion venom-55 ℃ of following lyophilizations, is obtained the scorpion venom lyophilized powder; Get 10g scorpion venom lyophilized powder and add the 500ml distilled water diluting, high speed centrifugation 20min under 10000r/min gets the filtering with microporous membrane that supernatant is successively used 0.45 μ m and 0.22 μ m, with the lyophilizing of gained filtrate (temperature-55 ℃), obtains Buthotoxin polypeptide dry powder; Getting 10mg Buthotoxin polypeptide dry powder joins and adds Mel 1g in the 100ml distilled water again and mix well and make nutritional solution.
Embodiment four:
Scorpion venom-45 ℃ of following lyophilizations, is obtained the scorpion venom lyophilized powder; Get 10g scorpion venom lyophilized powder and add the 500ml distilled water diluting, high speed centrifugation 20min under 10000r/min gets the filtering with microporous membrane that supernatant is successively used 0.45 μ m and 0.22 μ m, with the lyophilizing of gained filtrate (temperature-45 ℃), obtains Buthotoxin polypeptide dry powder; Add 10mg Buthotoxin polypeptide dry powder mixing in the 100ml 30 degree Chinese liquor and make nutrition wine.
Embodiment five:
Scorpion venom-60 ℃ of following lyophilizations, is obtained the scorpion venom lyophilized powder; Get 10g scorpion venom lyophilized powder and add the 800ml distilled water diluting, high speed centrifugation 10min under 15000r/min gets the filtering with microporous membrane that supernatant is successively used 0.45 μ m and 0.22 μ m, with the lyophilizing of gained filtrate (temperature-60 ℃), obtains Buthotoxin polypeptide dry powder; Add 50mg Buthotoxin polypeptide dry powder mixing in the 100ml 28 degree Chinese liquor and make nutrition wine.
Embodiment six:
Scorpion venom-50 ℃ of following lyophilizations, is obtained the scorpion venom lyophilized powder; Get 10g scorpion venom lyophilized powder and add the 1000ml distilled water diluting, high speed centrifugation 15min under 15000r/min gets the filtering with microporous membrane that supernatant is successively used 0.45 μ m and 0.22 μ m, with the lyophilizing of gained filtrate (temperature-50 ℃), obtains Buthotoxin polypeptide dry powder; Add 100mg Buthotoxin polypeptide dry powder mixing in the 100ml 42 degree Chinese liquor and make nutrition wine.
Embodiment seven:
Scorpion venom-80 ℃ of following lyophilizations, is obtained the scorpion venom lyophilized powder; Get 10g scorpion venom lyophilized powder and add the 1000ml distilled water diluting, high speed centrifugation 20min under 10000r/min gets the filtering with microporous membrane that supernatant is successively used 0.45 μ m and 0.22 μ m, with the lyophilizing of gained filtrate (temperature-80 ℃), obtains Buthotoxin polypeptide dry powder; Add 1mg Buthotoxin polypeptide dry powder mixing in the 100ml 35 degree Chinese liquor and make nutrition wine.
Claims (5)
1, a kind of peptide nutrient liquid is characterized in that preparing in accordance with the following methods: (1) extracts scorpion venom, and lyophilization obtains the scorpion venom lyophilized powder; (2) with the dilution of scorpion venom lyophilized powder adding distil water, high speed centrifugation extracts Buthotoxin polypeptide, and lyophilization gets Buthotoxin polypeptide dry powder; (3) Buthotoxin polypeptide dry powder is made nutritional solution.
2, peptide nutrient liquid according to claim 1 is characterized in that described lyophilization temperature is-45 ℃～-80 ℃.
3, peptide nutrient liquid according to claim 1 is characterized in that described high speed centrifugation rotating speed is 10000～15000r/min, and the time is 10～20min.
4, peptide nutrient liquid according to claim 1 is characterized in that the peptide oral liquid of making a living, and adds Buthotoxin polypeptide dry powder 1～100mg in the 100ml water, adds flavoring agent Mel then.
5, peptide nutrient liquid according to claim 1 is characterized in that the peptide nutritious wine of making a living, and adds Buthotoxin polypeptide dry powder 1～100mg in 28 °～420 ° Chinese liquor of 100ml.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2005100441024A CN1891233A (en) | 2005-07-08 | 2005-07-08 | Peptide nutrient liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2005100441024A CN1891233A (en) | 2005-07-08 | 2005-07-08 | Peptide nutrient liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1891233A true CN1891233A (en) | 2007-01-10 |
Family
ID=37596593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2005100441024A Pending CN1891233A (en) | 2005-07-08 | 2005-07-08 | Peptide nutrient liquid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1891233A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103849540A (en) * | 2014-03-13 | 2014-06-11 | 陈海峰 | Snake-scorpion qi-replenishing health-care wine and preparation method thereof |
| CN103861078A (en) * | 2014-03-13 | 2014-06-18 | 陈海峰 | Snake-scorpion pain-relieving and wind-dispelling liquor and preparation method thereof |
| CN104306406A (en) * | 2014-11-07 | 2015-01-28 | 山东中医药大学 | Scorpion ferment and ultra-filtrated object, and preparation procedure and usage thereof |
-
2005
- 2005-07-08 CN CNA2005100441024A patent/CN1891233A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103849540A (en) * | 2014-03-13 | 2014-06-11 | 陈海峰 | Snake-scorpion qi-replenishing health-care wine and preparation method thereof |
| CN103861078A (en) * | 2014-03-13 | 2014-06-18 | 陈海峰 | Snake-scorpion pain-relieving and wind-dispelling liquor and preparation method thereof |
| CN103861078B (en) * | 2014-03-13 | 2018-04-27 | 陈海峰 | A kind of snakes and scorpions analgesia liquor for treating rheumatism and preparation method thereof |
| CN104306406A (en) * | 2014-11-07 | 2015-01-28 | 山东中医药大学 | Scorpion ferment and ultra-filtrated object, and preparation procedure and usage thereof |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |