CN103861078B - A kind of snakes and scorpions analgesia liquor for treating rheumatism and preparation method thereof - Google Patents

A kind of snakes and scorpions analgesia liquor for treating rheumatism and preparation method thereof Download PDF

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CN103861078B
CN103861078B CN201410095455.6A CN201410095455A CN103861078B CN 103861078 B CN103861078 B CN 103861078B CN 201410095455 A CN201410095455 A CN 201410095455A CN 103861078 B CN103861078 B CN 103861078B
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snakes
scorpions
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CN103861078A (en
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陈海峰
孔天翰
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Chen Haifeng
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Abstract

The present invention relates to medicinal liquor technical field, more particularly to a kind of snakes and scorpions analgesia liquor for treating rheumatism and preparation method thereof, the present invention includes radix cyathulae, levisticum, cortex acanthopanacis, erythrina bark, Chinese cassia tree, Ligusticum wallichii, Angelica sinensis, Radix Codonopsis, the root of Chinese clematis, the windproof, bark of eucommia, monkshood, tripterygium wilfordii, Semen Strychni (processed), radix glycyrrhizae, snake venom polypeptide, Buthotoxin polypeptide, honey and wine;Prepared using percolation, not only production method is simple, but also convenient to take, comfortable taste, especially can effectively treat the diseases such as arthralgia pain due to rheumatism, muscles and bones contraction.

Description

A kind of snakes and scorpions analgesia liquor for treating rheumatism and preparation method thereof
Technical field
The present invention relates to medicinal liquor technical field, more particularly to a kind of snakes and scorpions analgesia liquor for treating rheumatism and preparation method thereof.
Background technology
Wine is known as the title of " length of hundred medicines ".Modern research shows that the main component ethanol of wine(It is commonly called as alcohol)It is a kind of good Good semi-polarity organic solvent,.The Multiple components of Chinese medicine such as alkaloid, salt, tannin, volatile oil, organic acid, resin, carbohydrate And partial pigment(Such as chlorophyll, lutein)Deng being relatively easily soluble in ethanol.Ethanol not only has good penetrability, be easy into Enter in medicinal material histocyte, play dissolution, promote displacement, diffusion, be conducive to improve leaching velocity and leaching effect;Also Antisepsis, can delay the hydrolysis of many medicines, strengthen the stability of medicament.
The medicinal liquor that will be integrated as the wine of beverage and the medicine " molten " to promote health and cure diseases, not only has and prepares, takes simplicity, medicine Property stablize, it is safe and effective the advantages of, more because wine assisting drug, wine help medicine gesture and gives full play to effect, improve curative effect.
Class is used as medicine before two thousand years《Sheng Nong's herbal classic》In it is just on the books, and whole body has medical value. Meat of snake plays the role of invigorate blood circulation wind dispelling, eliminating phlegm clearing damp, tonifying middle-Jiao and Qi, insane to rheumathritis, extremity numbness, Qi and blood deficiency, infantile convulsion The disease such as epilepsy and pruitus all has a better effect.Snake gall, snake bone, snake slough(Prescription name pericarpium juglandis, is commonly called as snake shell, snake clothing), it is right Sciatica is treated, antimigraine, rheumatoid arthrosis pain and advanced cancer, leprosy etc. have a better effect.Wherein snake venom valency Lattice are medicine sources very in short supply on international market than also expensive ten times of gold.
Scorpion laudatory title mountain shrimp, pincers scorpion, medicine medicinal history thousands of years existing, according to《Compendium of Materia Medica》Scorpio tool is recorded in detail There is the effect of " ceases wind antispastic, dispersing pathogen accumulation, remove obstruction in channels to relieve pain ".Have to illnesss such as facial paralysis, rheumatism, scapulohumeral periarthritis and significantly treat The effect of effect, and has anti-cancer, anticancer.Scorpion wine, the analgesia of Chang Yinke ceases winds, detoxicating and resolving a mass, remove obstruction in channels to relieve pain.Scorpion wine contains human body 22 kinds of required amino acid and various trace elements and vitamin, Taurine etc., it is without any side effects to patient, it is men and women The suitable for people of all ages and high-grade nutrient agriculture tonic that keeps fit and healthy, its function can two-way raising function of human body, physiological function, to nerveous system System, cardio-cerebrovascular and liver, kidney, skin have the effect of good, to treatment rheumatism, shoulder pain, shoulder inflammation, headache, facial paralysis, women Pain in the back etc. has positive effect.
But existing snakes and scorpions wine is typically all that whole snake and scorpion are arranged in pairs or groups after some Chinese medicines, is placed directly in white wine Soaked, when treatment directly drinks use.On the one hand it is inconvenient because there is medicinal material impurity to drink, its therapeutic efficiency is not bright enough Really, on the other hand because snakes and scorpions is whole is put into so that dissolve more heavy substances in wine.And snakes and scorpions has certain toxicity, it is steep in wine Cannot disorderly it drink:The toxicity of the poisonous snakes such as cobra, green bamboo snake is all very big, and can neither be taken orally easily with the medicinal liquor of its bubble can not be outer With.Snake venom may penetrate into skin, influence renal function, also the unknown toxicity entail dangers to life in some snake bodies.
The content of the invention
To solve the above-mentioned problems, it is an object of the present invention to provide it is a kind of it is safe, drink the analgesia of convenient snakes and scorpions and drive Wind wine;It not only effectively treats the diseases such as arthralgia pain due to rheumatism, muscles and bones contraction, and production method is simple, evident in efficacy.
The second object of the present invention is to provide the preparation method of the snakes and scorpions analgesia liquor for treating rheumatism.
The present invention is achieved through the following technical solutions:
A kind of snakes and scorpions analgesia liquor for treating rheumatism, is mainly made of active compound extract and wine;Solid night ratio between the active compound and wine For 1:12~1:13(Grams per milliliter);
The active compound includes the following material calculated in parts by weight:
5~15 parts of radix cyathulae, 5~15 parts of levisticum, 5~15 parts of cortex acanthopanacis, 5~15 parts of erythrina bark, 5~15 parts of Chinese cassia tree, river 5~15 parts of rhizome of chuanxiong, 5~10 parts of Angelica sinensis, 5~15 parts of Radix Codonopsis, 5~10 parts of the root of Chinese clematis, 5~10 parts windproof, 5~10 parts of the bark of eucommia, monkshood 5 ~10 parts, 1~3 part of tripterygium wilfordii, 1~3 part of Semen Strychni (processed), 15~25 parts of radix glycyrrhizae, 0.1~0.5 part of snake venom polypeptide, Buthotoxin polypeptide 0.1~0.3 part.
It is preferred that the active compound includes the following material calculated in parts by weight:
10 parts of radix cyathulae, 10 parts of levisticum, 10 parts of cortex acanthopanacis, 10 parts of erythrina bark, 10 parts of Chinese cassia tree, 10 parts of Ligusticum wallichii, 10 parts of Angelica sinensis, 10 parts of Radix Codonopsis, 5 parts of the root of Chinese clematis, 5 parts windproof, 5 parts of the bark of eucommia, 5 parts of monkshood, 3 parts of tripterygium wilfordii, 1.5 parts of Semen Strychni (processed), 20 parts of radix glycyrrhizae, 0.15 part of 0.30 part of snake venom polypeptide and Buthotoxin polypeptide.
It is preferred that the liquid substance further includes honey, the volume ratio of the honey and white wine is 1:30.
It is preferred that the tripterygium wilfordii band dermatome.
It is preferred that the Semen Strychni (processed) processs gained for husky boiling hot big gun.
It is preferred that the wine is 55 ± 3 ° of white wine.
The preparation method of the snakes and scorpions analgesia liquor for treating rheumatism, is specially:
First by the radix cyathulae of the amount, levisticum, cortex acanthopanacis, erythrina bark, Chinese cassia tree, Ligusticum wallichii, Angelica sinensis, Radix Codonopsis, the root of Chinese clematis, anti- Wind, the bark of eucommia, monkshood, tripterygium wilfordii, Semen Strychni (processed), 15 taste traditional Chinese medicine powder of radix glycyrrhizae are broken into thick end, and active compound filtrate is made using percolation;
Stirred evenly again toward the honey that the amount is added in active compound filtrate, liquid is filtered out after standing a few days;
The snake venom polypeptide and Buthotoxin polypeptide of the amount are finally added, the snakes and scorpions analgesia liquor for treating rheumatism is made after stirring evenly.
Wherein, the preparation of the active compound filtrate:
The 15 taste traditional Chinese medicine powder is first broken into coarse powder, add suitable white wine infiltration 2~4 it is small when, fill medicinal material coarse powder Part expansion;
Then, the percolation filter that bottom is lined with absorbent cotton is uniformly charged by several times(Percolation filtration extraction pot)In, used after installing every time Wooden stick compresses;Install Chinese medicine, gauze in upper cover, and the handstone for pressing last layer to clean, in order to avoid make medicinal powder after adding white wine Float.
Then the switch of mouth under percolation filter is opened, then adds white wine from percolation filter top at leisure, when liquid is from lower mouth stream Upper switch is closed when going out, so that the liquid of outflow is poured into percolation filter, continuously add white wine is for several centimeters to high drug powder Only, lower mouth switch is opened after when capping placement 24~48 is small, percolate is slowly flowed out, the active compound filtrate is made.
Wherein, the preparation of the snake venom polypeptide:
Taking snake venom, slightly malicious freeze-dried powder is dissolved in deionized water and is made into the snake venom of 40g/L slightly malicious solution, 18000rpm4 DEG C of centrifugation 30min, takes supernatant, 4 DEG C of preservations;
Sephadex G-75 gel columns (φ 55cm X50cm) are stayed overnight with deionized water balance in advance, by final proof on snake venom Product are loaded to the Sephadex G-75 gel columns after balance, applied sample amount 400mg/10ml;
Eluted after completion of the sample with deionized water, flow velocity 1.6ml/min;The thick poisons Sephadex G-75 column layers of snake venom After analysis, 4 eluting peaks are obtained;Collect 4 peaks(Finally elute), the snake venom polypeptide is obtained, cryogenic vacuum freezes spare.4 Nearly 10 kinds of cells, neural activity polypeptide are consisted predominantly of in peak, one's share of expenses for a joint undertaking amount is respectively less than 10kDa.
Wherein, the preparation of the Buthotoxin polypeptide:
Taking scorpion venom, slightly malicious freeze-dried powder is dissolved in deionized water and is made into the scorpion venom of 40g/L slightly malicious solution, 18000rpm4 DEG C of centrifugation 30min, takes supernatant, 4 DEG C of preservations;
Sephadex G-50 gel columns (φ 55cm X50cm) are stayed overnight with deionized water balance in advance, by final proof on scorpion venom Product are loaded to the Sephadex G-50 gel columns after balance, applied sample amount 400mg/10ml;
Eluted after completion of the sample with deionized water, flow velocity 1.6ml/min;The thick poisons SephadexG-50 column chromatographies of scorpion venom Afterwards, 3 eluting peaks are obtained;Collect 3 peaks(Finally elute), the Buthotoxin polypeptide is obtained, cryogenic vacuum freezes spare.3 peaks In consist predominantly of more than 10 kind cells, neural activity polypeptide, one's share of expenses for a joint undertaking amount is respectively less than 10kDa.
The usage of snakes and scorpions wine of the present invention:Oral, each taking 50-100 milliliters, day takes 2-3 times.
The present invention include radix cyathulae, levisticum, cortex acanthopanacis, erythrina bark, Chinese cassia tree, Ligusticum wallichii, Angelica sinensis, Radix Codonopsis, the root of Chinese clematis, it is windproof, The bark of eucommia, monkshood, tripterygium wilfordii, Semen Strychni (processed), radix glycyrrhizae, snake venom polypeptide, Buthotoxin polypeptide, honey and wine.Wherein described snake venom polypeptide and Buthotoxin polypeptide is the active ingredient that a kind of activity is strong, sphere of action is wide.They carry out compatibility with above-mentioned Chinese medicine and wine, utilize them Between mutual synergistic effect, prepared by using percolation.It is not only convenient to take, comfortable taste.And can effectively it control The diseases such as arthralgia pain due to rheumatism, muscles and bones contraction are treated, production method is simple, evident in efficacy.Function:Qi and activate blood circulation, dispelling wind and removing obstruction in the meridians, analgesia. Cure mainly:The diseases such as derangement of Qi and blood, limbs pain, Feng Shi Paralysis resistances, muscle arteries and veins contraction.
Specific embodiment
With reference to embodiment, the present invention is described in further detail, is managed to help those skilled in the art The solution present invention.
Embodiment 1
A kind of snakes and scorpions analgesia liquor for treating rheumatism, is prepared by following active compound:10 grams of radix cyathulae, 10 grams of levisticum, 10 grams of cortex acanthopanacis, 10 grams of erythrina bark, 10 grams of Chinese cassia tree, 10 grams of Ligusticum wallichii, 10 grams of Angelica sinensis, 10 grams of Radix Codonopsis, 5 grams of the root of Chinese clematis, windproof 5 grams, 5 grams of the bark of eucommia, monkshood 5 grams, tripterygium wilfordii(Band dermatome)3 grams, Semen Strychni (processed)(Sand scalds)1.5 grams, 20 grams of radix glycyrrhizae, 0.30 gram of snake venom polypeptide, Buthotoxin polypeptide 0.15 gram, honey 50ml, white wine 1500ml(55±3°).
The preparation method of snakes and scorpions analgesia liquor for treating rheumatism, is specially:
(1), snake venom polypeptide preparation:
Taking snake venom, slightly malicious freeze-dried powder is dissolved in deionized water and is made into the snake venom of 40g/L slightly malicious solution, 18000rpm4 DEG C of centrifugation 30min, takes supernatant, 4 DEG C of preservations;
Sephadex G-75 gel columns (φ 55cm X50cm) are stayed overnight with deionized water balance in advance, by final proof on snake venom Product are loaded to the Sephadex G-75 gel columns after balance, applied sample amount 400mg/10ml;
Eluted after completion of the sample with deionized water, flow velocity 1.6ml/min;The thick poisons Sephadex G-75 column layers of snake venom After analysis, 4 eluting peaks are obtained;Collect 4 peaks(Finally elute), the snake venom polypeptide is obtained, cryogenic vacuum freezes spare.
(2), Buthotoxin polypeptide preparation:
Taking scorpion venom, slightly malicious freeze-dried powder is dissolved in deionized water and is made into the scorpion venom of 40g/L slightly malicious solution, 18000rpm4 DEG C of centrifugation 30min, takes supernatant, 4 DEG C of preservations;
Sephadex G-50 gel columns (φ 55cm X50cm) are stayed overnight with deionized water balance in advance, by final proof on scorpion venom Product are loaded to the Sephadex G-50 gel columns after balance, applied sample amount 400mg/10ml;
Eluted after completion of the sample with deionized water, flow velocity 1.6ml/min;The thick poisons Sephadex G-50 column layers of scorpion venom After analysis, 3 eluting peaks are obtained;Collect 3 peaks(Finally elute), the Buthotoxin polypeptide is obtained, cryogenic vacuum freezes spare.
(3), active compound filtrate preparation:
15 taste traditional Chinese medicine powders are first broken into coarse powder, add suitable white wine infiltration 2~4 it is small when, medicinal material coarse powder is filled part swollen It is swollen;
Then, the percolation filter that bottom is lined with absorbent cotton is uniformly charged by several times(Percolation filtration extraction pot)In, used after installing every time Wooden stick compresses;Install Chinese medicine, gauze in upper cover, and the handstone for pressing last layer to clean, in order to avoid make medicinal powder after adding white wine Float.
Then the switch of mouth under percolation filter is opened, then adds white wine from percolation filter top at leisure, when liquid is from lower mouth stream Upper switch is closed when going out, so that the liquid of outflow is poured into percolation filter, continuously add white wine is for several centimeters to high drug powder Only, lower mouth switch is opened after when capping placement 24~48 is small, percolate is slowly flowed out, the active compound filtrate is made.
(4), snakes and scorpions analgesia liquor for treating rheumatism preparation:
First by the radix cyathulae of the amount, levisticum, cortex acanthopanacis, erythrina bark, Chinese cassia tree, Ligusticum wallichii, Angelica sinensis, Radix Codonopsis, the root of Chinese clematis, anti- Wind, the bark of eucommia, monkshood, tripterygium wilfordii, Semen Strychni (processed), 15 taste traditional Chinese medicine powder of radix glycyrrhizae are broken into thick end, and active compound filtrate is made using percolation; Stirred evenly again toward the honey that the amount is added in active compound filtrate, liquid is filtered out after standing a few days;The snake venom for finally adding the amount is more Peptide and Buthotoxin polypeptide, are made the snakes and scorpions analgesia liquor for treating rheumatism after stirring evenly.
Embodiment 2
A kind of snakes and scorpions analgesia liquor for treating rheumatism, is prepared by following active compound:15 grams of radix cyathulae, 15 grams of levisticum, 15 grams of cortex acanthopanacis, 5 grams of erythrina bark, 5 grams of Chinese cassia tree, 5 grams of Ligusticum wallichii, 5 grams of Angelica sinensis, 15 grams of Radix Codonopsis, 10 grams of the root of Chinese clematis, windproof 5 grams, 5 grams of the bark of eucommia, monkshood 5 Gram, tripterygium wilfordii(Band dermatome)2 grams, Semen Strychni (processed)(Sand scalds)2.4 grams, 15 grams of radix glycyrrhizae, 0.45 gram of snake venom polypeptide, Buthotoxin polypeptide 0.1 Gram, honey 50ml, white wine 1500ml(55±3°).
The preparation method of snakes and scorpions analgesia liquor for treating rheumatism, with embodiment 1.
Embodiment 3
A kind of snakes and scorpions analgesia liquor for treating rheumatism, is prepared by following active compound:5 grams of radix cyathulae, 5 grams of levisticum, 5 grams of cortex acanthopanacis, sea 10 grams of paulownia skin, 10 grams of Chinese cassia tree, 10 grams of Ligusticum wallichii, 10 grams of Angelica sinensis, 5 grams of Radix Codonopsis, 5 grams of the root of Chinese clematis, windproof 10 grams, 10 grams of the bark of eucommia, monkshood 10 grams, tripterygium wilfordii(Band dermatome)1.55 grams, Semen Strychni (processed)(Sand scalds)3 grams, 25 grams of radix glycyrrhizae, 0.1 gram of snake venom polypeptide, Buthotoxin polypeptide 0.3 gram, honey 50ml, white wine 1500ml(55±3°).
The preparation method of snakes and scorpions analgesia liquor for treating rheumatism, with embodiment 1.
Embodiment 4
A kind of snakes and scorpions analgesia liquor for treating rheumatism, is prepared by following active compound:5 grams of radix cyathulae, 5 grams of levisticum, 5 grams of cortex acanthopanacis, sea 15 grams of paulownia skin, 15 grams of Chinese cassia tree, 15 grams of Ligusticum wallichii, 10 grams of Angelica sinensis, 5 grams of Radix Codonopsis, 5 grams of the root of Chinese clematis, windproof 5 grams, 5 grams of the bark of eucommia, monkshood 5 Gram, tripterygium wilfordii(Band dermatome)2.2 grams, Semen Strychni (processed)(Sand scalds)2 grams, 15 grams of radix glycyrrhizae, 0.5 gram of snake venom polypeptide, Buthotoxin polypeptide 0.25 Gram, honey 50ml, white wine 1500ml(55±3°).
The preparation method of snakes and scorpions analgesia liquor for treating rheumatism, with embodiment 1.
Above-described embodiment, simply presently preferred embodiments of the present invention, is not used for limiting the scope of the present invention, therefore all with this The equivalent change or modification that feature and principle described in invention claim are done, should all be included in scope of the invention as claimed Within.
The present invention passes through carries out follow-up investigations to more than 30 a patients,
Certain man, age:45 years old, native place:Guangdong, medical history:Knee joint rheumatalgia 5 years
Treatment:Oral, each taking 50 milliliters, day takes 2-3 times, takes 15 days, and pain symptom improves, after taking 3 months, knee Close without pain.
Certain man, age:60 years old, native place:Guangdong, medical history:Knee joint rheumatalgia 10 years
Treatment:Oral, each taking 100 milliliters, day takes 2-3 times, takes 30 days, and pain symptom improves, after taking 3 months, Knee is closed without pain.
Certain female, age:45 years old, native place:Hunan, medical history:Ten articulations digitorum manus rheumatalgia 3 years
Treatment:Oral, each taking 50 milliliters, day takes 2-3 times, takes 10 days, and pain symptom improves, after taking 1 month, knee Close without pain.
Certain man, age:70 years old, native place:Guizhou, medical history:Had a pain in the leg caused by muscles and bones contraction for more than 10 years
Treatment:Oral, each taking 60 milliliters, day takes 2-3 times, takes 20 days, and the symptom that has a pain in the leg improves, after taking 2 months, leg Without pain.
More than be partial results come illustrate the present invention effect, it is other not enumerate.

Claims (8)

  1. The wind dispelling white wine 1. a kind of snakes and scorpions is eased pain, is mainly made of active compound extract and wine;It is characterized in that, the active compound and wine it Between solid-to-liquid ratio be 1:12~1:13 (grams per milliliters);
    The active compound includes the following material calculated in parts by weight:
    5~15 parts of radix cyathulae, 5~15 parts of levisticum, 5~15 parts of cortex acanthopanacis, 5~15 parts of erythrina bark, 5~15 parts of Chinese cassia tree, Ligusticum wallichii 5~ 15 parts, 5~10 parts of Angelica sinensis, 5~15 parts of Radix Codonopsis, 5~10 parts of the root of Chinese clematis, 5~10 parts windproof, 5~10 parts of the bark of eucommia, monkshood 5~10 Part, 1~3 part of tripterygium wilfordii, 1~3 part of Semen Strychni (processed), 15~25 parts of radix glycyrrhizae, 0.1~0.5 part of snake venom polypeptide and Buthotoxin polypeptide 0.1~ 0.3 part;
    The preparation of the snake venom polypeptide:
    Taking snake venom, slightly malicious freeze-dried powder is dissolved in deionized water and is made into the snake venom of 40g/L slightly malicious solution, 4 DEG C of centrifugations of 18000rpm 30min, takes supernatant, 4 DEG C of preservations;
    Sephadex G-75 gel columns, specification areStayed overnight in advance with deionized water balance, by snake venom Final proof product are loaded to the Sephadex G-75 gel columns after balance, applied sample amount 400mg/10ml;
    Eluted after completion of the sample with deionized water, flow velocity 1.6ml/min;After the thick poisons Sephadex G-75 column chromatographies of snake venom, 4 eluting peaks are obtained;4 peaks are collected, obtain the snake venom polypeptide, cryogenic vacuum freezes spare;
    The preparation of the Buthotoxin polypeptide:
    Taking scorpion venom, slightly malicious freeze-dried powder is dissolved in deionized water and is made into the scorpion venom of 40g/L slightly malicious solution, 4 DEG C of centrifugations of 18000rpm 30min, takes supernatant, 4 DEG C of preservations;
    Sephadex G-50 gel columns, specification areStayed overnight in advance with deionized water balance, by scorpion venom Final proof product are loaded to the Sephadex G-50 gel columns after balance, applied sample amount 400mg/10ml;
    Eluted after completion of the sample with deionized water, flow velocity 1.6ml/min;After the thick poisons Sephadex G-50 column chromatographies of scorpion venom, 3 eluting peaks are obtained;3 peaks are collected, obtain the Buthotoxin polypeptide, cryogenic vacuum freezes spare.
  2. The wind dispelling white wine 2. snakes and scorpions according to claim 1 is eased pain, it is characterised in that the active compound is included in parts by weight The following material calculated:
    10 parts of radix cyathulae, 10 parts of levisticum, 10 parts of cortex acanthopanacis, 10 parts of erythrina bark, 10 parts of Chinese cassia tree, 10 parts of Ligusticum wallichii, 10 parts of Angelica sinensis, Radix Codonopsis 10 parts, 5 parts of the root of Chinese clematis, 5 parts windproof, 5 parts of the bark of eucommia, 5 parts of monkshood, 3 parts of tripterygium wilfordii, 1.5 parts of Semen Strychni (processed), 20 parts of radix glycyrrhizae, snake venom 0.15 part of 0.30 part of polypeptide and Buthotoxin polypeptide.
  3. The wind dispelling white wine 3. snakes and scorpions according to claim 1 or 2 is eased pain, it is characterised in that the snakes and scorpions analgesia wind dispelling white wine Honey is further included, the volume ratio of the honey and wine is 1:30.
  4. The wind dispelling white wine 4. snakes and scorpions according to claim 1 or 2 is eased pain, it is characterised in that the tripterygium wilfordii band dermatome.
  5. The wind dispelling white wine 5. snakes and scorpions according to claim 1 or 2 is eased pain, it is characterised in that the Semen Strychni (processed) is husky boiling hot big gun Process gained.
  6. The wind dispelling white wine 6. snakes and scorpions according to claim 1 or 2 is eased pain, it is characterised in that the wine is 55 ± 3 ° of white wine.
  7. 7. the preparation method of snakes and scorpions analgesia wind dispelling white wine described in any one in claim 1~6, it is characterised in that be specially:
    First by the radix cyathulae of the amount, levisticum, cortex acanthopanacis, erythrina bark, Chinese cassia tree, Ligusticum wallichii, Angelica sinensis, Radix Codonopsis, the root of Chinese clematis, windproof, Du Secondary, monkshood, tripterygium wilfordii, Semen Strychni (processed), 15 taste traditional Chinese medicine powder of radix glycyrrhizae are broken into thick end, and active compound filtrate is made using percolation;Stand Liquid is filtered out after a few days;
    The snake venom polypeptide and Buthotoxin polypeptide of the amount are added again, and the snakes and scorpions analgesia wind dispelling white wine is made after stirring evenly.
  8. 8. the preparation method of snakes and scorpions analgesia wind dispelling white wine according to claim 7, it is characterised in that the active compound filtrate Prepare:
    First by radix cyathulae, levisticum, cortex acanthopanacis, erythrina bark, Chinese cassia tree, Ligusticum wallichii, Angelica sinensis, Radix Codonopsis, the root of Chinese clematis, the windproof, bark of eucommia, monkshood, Tripterygium wilfordii, Semen Strychni (processed), 15 taste traditional Chinese medicine powder of radix glycyrrhizae are broken into coarse powder, add suitable white wine infiltration 2~4 it is small when, make medicinal material thick Powder fully expands;
    Then, bottom is uniformly charged by several times to be lined with the percolation filter of absorbent cotton, compressed after installing every time with wooden stick;
    Then the switch of mouth under percolation filter is opened, then adds white wine from percolation filter top at leisure, when liquid is flowed out from lower mouth Upper switch to be closed, so that the liquid of outflow is poured into percolation filter, continuously adds white wine to high drug powder, capping places 24~ 48 it is small when after open lower mouth switch, percolate is slowly flowed out, the active compound filtrate be made.
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CN105311074A (en) * 2014-07-30 2016-02-10 高晓燕 Formulation for treating arthralgia
CN115006486A (en) * 2022-05-30 2022-09-06 刘汉有 Antirheumatic medicinal liquor and using method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1198934A (en) * 1997-05-09 1998-11-18 司纪圣 Medicated wine for curing rheumarthritis and rheumatoid arthritis and its preparation process
CN1891233A (en) * 2005-07-08 2007-01-10 黄巨轮 Peptide nutrient liquid
CN103555527A (en) * 2013-10-24 2014-02-05 重庆师范大学 Snake peptide healthcare wine and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1198934A (en) * 1997-05-09 1998-11-18 司纪圣 Medicated wine for curing rheumarthritis and rheumatoid arthritis and its preparation process
CN1891233A (en) * 2005-07-08 2007-01-10 黄巨轮 Peptide nutrient liquid
CN103555527A (en) * 2013-10-24 2014-02-05 重庆师范大学 Snake peptide healthcare wine and preparation method thereof

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