CN105998246A - Externally-used traditional Chinese medicine paste for treating painful heel and preparation method thereof - Google Patents
Externally-used traditional Chinese medicine paste for treating painful heel and preparation method thereof Download PDFInfo
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- CN105998246A CN105998246A CN201610548526.2A CN201610548526A CN105998246A CN 105998246 A CN105998246 A CN 105998246A CN 201610548526 A CN201610548526 A CN 201610548526A CN 105998246 A CN105998246 A CN 105998246A
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- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention provides externally-used traditional Chinese medicine paste for treating painful heel. The past is prepared from 10-20 parts of common clubmoss herb, 10-20 parts of spina gleditsiae, 10-20 parts of rhizoma drynariae, 10-20 parts of bark of eucommia, 10-20 parts of rhizoma corydalis, 10-20 parts of caulis spatholobi, 10-20 parts of papayas, 10-20 parts of radix clematidis, 10-20 parts of fructus psoraleae, 10-20 parts of radix dipsaci, 10-20 parts of philippine flemingia roots, 10-20 parts of roots of stephania tetrandra, 10-20 parts of rhizoma chuanxiong, 10-20 parts of caulis impatientis, 10-20 parts of radix notoginseng, 10-20 parts of myrrh, 10-20 parts of frankincense, 10-20 parts of herba asari, 10-20 parts of lumbricus, 10-20 parts of ground beetles, 10-20 parts of divaricate saposhnikovia roots, 10-20 parts of cortex acanthopanacis, 10-20 parts of radix angelicae pubescentis, 10-20 parts of caulis sargentodoxae, 10-20 parts of folium artemisiae argyi, 10-20 parts of ramulus mori and 10-20 parts of fennel fruit. In ancient, the paste has the statement that the paste can treat the painful heel through traditional Chinese medicine and has the same effect as a decoction, and if the paste is used in the proper way, the treatment effect is achieved at once. The paste can relieve or eliminate the symptom.
Description
Technical field
The present invention relates to containing the medical configuration product deriving from plant, animal or mineral component, particularly to a kind of Chinese medicinal external-application ointment treating talalgia and preparation method thereof.
Background technology
Traditional Chinese Medicine early has research to the disease of talalgia, and Sui Dynasty famous physician Chao Yuanfang (550-630 A.D.) talalgia is called " heel is ruined ", book cloud: " heel ruined person heel neglects pain, must not also, common customs are exhaled as heel ruined." big physician's ZHU Dan-xi of one of Au element in " danxi's experiential therapy " referred to as " talalgia ", it is necessary to use the attached cream in osmanthus.
Plaster is a wonderful work of motherland's medical science, and Gu has the saying such as " reason of the external treatment i.e. reason for the treatment of by oral administration of medicines, the medicine of the external treatment i.e. medicine for the treatment of by oral administration of medicines, different person, method ear ", " it is sick that plaster can control treatment by Chinese herbs macLean-Maxwell disease, and not different from decoction is done in the proper way, and it rings vertical answering " with it.The Qing Dynasty's famous physician Xu Ling tire is said: " modern plaster used, the plaster applying a plaster for therapeutic purpose of ancients' meaning..... control inner person, or wind dispelling trembled with fear, or and QI and blood, or expectorant painful abdominal mass, or strengthening bone and muscle, its side very spirit, medicine also adds and subtracts with disease, and its cream preferably weigh thick long paste.”
Traditional Chinese medical science QI and blood theory is thought, qi-blood circulating process is the material base that all histoorgans of human body are operated, QI-blood circulating regularly freely balances as expensive, if QI and blood is the most smooth will produce blood stasis, blood stasis hinders in internal, will further result in the deterioration of qi-blood circulating, cause more serious stasis of blood plug, therefore the traditional Chinese medical science is with QI and blood as guiding principle, be allowed to smooth balance by regulating qi and activating blood, can disease-relieving and physique enhancing, unsting and invigorate blood circulation.Talalgia is one of common ailment of middle-aged and old, usually heel portion pain occurs without obvious inducement, substantially increases the weight of for its feature, to have a strong impact on the life of middle-aged and elderly people after difficulty in walking, and walk load.Talalgia name of disease is the disease named with heel portion pain.Heel portion is the major part that human body bears a heavy burden, and has following anatomical features: heel skin is position the thickest in human body, and its subcutaneous fat is fine and close and flourishing, also known as fat pad.With the presence of synovial bursa between fat and calcaneus.Sole of the foot fascia and flexor digitorum brevis are attached to calcaneal tuberosity front, and heel string is attached to the back upper place of calcaneal tuberosity in the form of sheets.
With advancing age, organism quality declines middle-aged and elderly people, and heel tissue is through the tissue dewaterings such as long-term chronic strain, fat pad, atrophy, regression;Elastic reduction, simultaneously year the age increase skeleton decalcification gradually occur, plantar aponeurosis, tense situation during the inadaptable walking for a long time such as heel string, often at calcaneus attachment, damage the most slight courage and uprightness because being not suitable with tractive to ooze out, be with the passing of time excited into ostosis hyperosteogeny and produce bony spur.In addition there is pain in the synovial membrane sensation nerves such as also may result in synovial bursae inflammation that repeatedly rubs.The traditional Chinese medical science thinks that middle-aged and elderly people kidney qi is gradually lost, and bone withers flaccidity of tendon and muscle, and QI and blood can not be moistened in foot, and exopathogen is taken advantage of the occasion numbness resistance passages through which vital energy circulates and caused pain.Surely belong to " arthromyodynia " category.
With the passing of time or from the beginning of talalgia, select numerous expelling wind and removing dampness, dispelling cold by warming the meridian, softening hardness and disperse swelling, the herbal medicine immersion of invigorating blood circulation analgesia or external application foot, not injured skin, without toxicity.Fumigation and wash method decocted by all liquid medicine, and medicine acts on local, permeates skin, through sick institute, promotes qi and blood circulation, improve local blood and run, soften bony spur, promote that inflammation absorbs, so that remission or elimination.
The modal reason of talalgia is that long-term, chronic, microtrauma accumulates the pathological changes caused, and shows as fracture and the repair process thereof of fascia fiber.Below calcaneus partially in fascia vicinity can have a hyperosteogeny, form bone ridge.Position, side X-ray photographs is shown as bony spur.The latter is considered as often the reason of talalgia, but clinical research proves that it is difficult to certainly with the cause effect relation of talalgia, and plantar fasciitis differs and establishes a capital with bony spur, has the people of calcanean spur also to differ and established a capital talalgia.The talalgia that plantar fasciitis causes can be cured naturally.Padded heel, alleviates the heel string pulling force to calcaneus, front plantar flexion of foot, alleviates the tension force of sole of the foot fascia, symptom all can be made to alleviate.Can carry out injection of drug by local pressure pain point inside foot root, once in a week, after injection, most patients can cure in two weeks.
From the angle analysis of the traditional Chinese medical science, talalgia belongs to the one of rheumatism involving the bone, how because of the hepatic and renal YIN deficiency, caused by cold-evil.Talalgia is a kind of disease that old people is common, sickness rate in young woman rises year by year the most now, particularly as white collar clan, the cooling slippers of fashion style is worn in working, and heel minister's phase exposes, easily by attacked by the cold and evil in air-conditioned room, After Hours being busy with going window-shopping, jumping slimnastics, foot fails again well to be had a rest, due to the long-term pressurized of heel, hyperkinesia with have a cold, cause heel fat fiber mat aseptic inflammation, finally induce pain.
Kidney is unit's the dominator of QI, kidney governing reproduction, main bone.According to meridians circulation route, heel belongs to the scope of kidney channel circulation.Talalgia is a kind of commonly encountered diseases, is characterized with heel swelling, numb pain, locally tenderness, difficulty in walking.Talalgia is also known as calcanean spur or heel bone hyperosteogeny.Belonging to " rheumatism involving the bone " category in Chinese medicine, pathogenic factor is many strains with old deficiency of the kidney, and wound is with to experience cold-damp relevant.With the passing of time or from the beginning of talalgia, select numerous expelling wind and removing dampness, dispelling cold by warming the meridian, softening hardness and disperse swelling, the herbal medicine immersion of invigorating blood circulation analgesia or external application foot, not injured skin, without toxicity.
Traditional Chinese Medicine early has research to the disease of talalgia, and Sui Dynasty famous physician Chao Yuanfang (550-630 A.D.) talalgia is called " heel is ruined ", book cloud: " heel ruined person heel neglects pain, must not also, common customs are exhaled as heel ruined." big physician's ZHU Dan-xi of one of Au element in " danxi's experiential therapy " referred to as " talalgia ", it is necessary to use the attached cream in osmanthus.The Qing Dynasty's famous physician Xu Ling tire is said: " modern plaster used, the plaster applying a plaster for therapeutic purpose of ancients' meaning..... control inner person, or wind dispelling trembled with fear, or and QI and blood, or expectorant painful abdominal mass, or strengthening bone and muscle, its side very spirit, medicine also adds and subtracts with disease, and its cream preferably weigh thick long paste.”
Doctor trained in Western medicine typically solves this problem with operation, though there being certain curative effect, but planting destructive operation, being propped up by calcaneus posterior tibial nerve and propping up cut-out with sural nerve, have side effect in various degree or cause some complication;Chinese medicine product then because of its draw materials natural, safety good, low side effect, documents and materials are abundant, clinical efficacy is good and enjoys favor.But existing prescription specific aim is poor, it is impossible to fundamentally alleviate the symptom of talalgia, and the most certain side effect.Therefore, the Chinese medicine composition finding a kind of highly effective and safe becomes the urgent needs of people.
Summary of the invention
The technical problem to be solved is, talalgia is a kind of commonly encountered diseases, is characterized with heel swelling, numb pain, locally tenderness, difficulty in walking.Talalgia is also known as calcanean spur or heel bone hyperosteogeny.Belonging to " rheumatism involving the bone " category in Chinese medicine, pathogenic factor is many strains with old deficiency of the kidney, and wound is with to experience cold-damp relevant.Doctor trained in Western medicine typically solves this problem with operation, though there being certain curative effect, but planting destructive operation, being propped up by calcaneus posterior tibial nerve and propping up cut-out with sural nerve, have side effect in various degree or cause some complication;Chinese medicine product then because of its draw materials natural, safety good, low side effect, documents and materials are abundant, clinical efficacy is good and enjoys favor.With the passing of time or from the beginning of talalgia, select the Chinese medicinal ointment external application foot of numerous expelling wind and removing dampness, dispelling cold by warming the meridian, softening hardness and disperse swelling, invigorating blood circulation analgesia, not injured skin, without toxicity.All medicines act on local, permeate skin, through sick institute, promote qi and blood circulation, improve local blood and run, soften bony spur, promote that inflammation absorbs, so that remission or elimination.Therefore, the Chinese medicinal external-application ointment finding a kind of highly effective and safe becomes the urgent needs of people.
nullFor solving these technical barriers,The invention provides a kind of Chinese medicinal external-application ointment treating talalgia,Its described Chinese medicinal external-application ointment can include the crude drug of following parts by weight: Herba Lycopodii 10~20 parts,Spina Gleditsiae 10~20 parts,Rhizoma Drynariae 10~20 parts,The Cortex Eucommiae 10~20 parts,Rhizoma Corydalis 10~20 parts,Caulis Spatholobi 10~20 parts,Fructus Chaenomelis 10~20 parts,Radix Clematidis 10~20 parts,Fructus Psoraleae 10~20 parts,Radix Dipsaci 10~20 parts,Radix Flemingiae Philippinensis 10~20 parts,Radix Stephaniae Tetrandrae 10~20 parts,Rhizoma Chuanxiong 10~20 parts,Herba speranskiae tuberculatae 10~20 parts,Radix Notoginseng 10~20 parts,Myrrha 10~20 parts,Olibanum 10~20 parts,Herba Asari 10~20 parts,Pheretima 10~20 parts,Eupolyphaga Seu Steleophaga 10~20 parts,Radix Saposhnikoviae 10~20 parts,Cortex Acanthopancis 10~20 parts,Radix Angelicae Pubescentis 10~20 parts,Caulis Sargentodoxae 10~20 parts,Folium Artemisiae Argyi 10~20 parts,Ramulus Mori 10~20 parts,Fructus Foeniculi 10~20 parts.
nullThe Chinese medicinal external-application ointment of described treatment talalgia,Its described Chinese medicinal external-application ointment can also include the crude drug of following parts by weight: Herba Lycopodii 10~15 parts,Spina Gleditsiae 10~15 parts,Rhizoma Drynariae 10~15 parts,The Cortex Eucommiae 10~15 parts,Rhizoma Corydalis 10~15 parts,Caulis Spatholobi 10~15 parts,Fructus Chaenomelis 10~15 parts,Radix Clematidis 10~15 parts,Fructus Psoraleae 10~15 parts,Radix Dipsaci 10~15 parts,Radix Flemingiae Philippinensis 10~15 parts,Radix Stephaniae Tetrandrae 10~15 parts,Rhizoma Chuanxiong 10~15 parts,Herba speranskiae tuberculatae 10~20 parts,Radix Notoginseng 10~20 parts,Myrrha 10~20 parts,Olibanum 10~20 parts,Herba Asari 10~20 parts,Pheretima 10~20 parts,Eupolyphaga Seu Steleophaga 10~20 parts,Radix Saposhnikoviae 10~20 parts,Cortex Acanthopancis 10~20 parts,Radix Angelicae Pubescentis 10~20 parts,Caulis Sargentodoxae 10~20 parts,Folium Artemisiae Argyi 10~20 parts,Ramulus Mori 10~20 parts,Fructus Foeniculi 10~20 parts.
nullThe Chinese medicinal external-application ointment of described treatment talalgia,Its described Chinese medicinal external-application ointment can also include the crude drug of following parts by weight: Herba Lycopodii 10~20 parts,Spina Gleditsiae 10~20 parts,Rhizoma Drynariae 10~20 parts,The Cortex Eucommiae 10~20 parts,Rhizoma Corydalis 10~20 parts,Caulis Spatholobi 10~20 parts,Fructus Chaenomelis 10~20 parts,Radix Clematidis 10~20 parts,Fructus Psoraleae 10~20 parts,Radix Dipsaci 10~20 parts,Radix Flemingiae Philippinensis 10~20 parts,Radix Stephaniae Tetrandrae 10~20 parts,Rhizoma Chuanxiong 10~20 parts,Herba speranskiae tuberculatae 10~15 parts,Radix Notoginseng 10~15 parts,Myrrha 10~15 parts,Olibanum 10~15 parts,Herba Asari 10~15 parts,Pheretima 10~15 parts,Eupolyphaga Seu Steleophaga 10~15 parts,Radix Saposhnikoviae 10~15 parts,Cortex Acanthopancis 10~15 parts,Radix Angelicae Pubescentis 10~15 parts,Caulis Sargentodoxae 10~15 parts,Folium Artemisiae Argyi 10~15 parts,Ramulus Mori 10~15 parts,Fructus Foeniculi 10~15 parts.
For solving above-mentioned technical problem, the present invention also provides for the preparation method of a kind of Chinese medicinal external-application ointment treating talalgia, and the preparation method of its described Chinese medicinal external-application ointment comprises the following steps:
A. take Radix Notoginseng, Herba Asari, Myrrha, Olibanum and the Radix Saposhnikoviae way of distillation and be vaporized into crystallization, pulverize dusting cover stand-by, as component 1.
B. the extraction of surplus stock medicinal alcohol is taken, as component 2;
C. by stripped for ethanol medicinal residues soak by water 2 times, concentrated extracting solution is merged, as component 3;
D. by 2-in-1 for component 1 component and be condensed into extractum, add component 1 and stir bottling.
In described step a, first crude drug Radix Notoginseng, Herba Asari, Myrrha, Olibanum and Radix Saposhnikoviae steam method can be distilled, obtain crystal, then pulverize, cross 100-120 mesh sieve, standby as component 1.
In described step b, can be shredded by remaining crude drug, be soaked and be placed in lid stainless steel cask, add 70% ethanol, quality is coarse grained 0.8-1 times, stirs, moistening airtight placement more than 1 hour, makes fully to expand;By bottom percolator filter plate gauze bag parcel pave after again the drug sample after moistening expansion is mixed pine do dissipate, then powder is contained with rustless steel spoon, load percolator uniformly, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurization, medicated powder loads 2/3 eminence that must not exceed percolator;Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, is then slowly added into 70% ethanol;Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, controlling percolation speed and be generally 1000g medical material outflow per minute 2~3ml, filtrate puts into liquid container, and pours ethanol during emptying into liquid container;Being merged by percolate and stand, stand for standby use, as component 2.
In described step c, can above-mentioned stripped raw material residue be put in 10 times amount water, soak 1-2 hour, heating extraction 2 times, each 1-2 hour, remove supernatant, united extraction liquid, 100-120 mesh filters, then the ultrafiltration post ultrafiltration that molecular weight is 5000-10000 through damming, the filtrate of 1.05 when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C, as component 3.
In described step d, component 2 can be merged with component 3, put in economic benefits and social benefits vacuum concentrator and mix, first concentrating the filtrate to relative density when 80 DEG C is the concentrated solution of 1.32, sets to 0~5 DEG C of deepfreezes 24 hours;The filter aid kieselguhr adding 0.3% by cold preservation liquid, filters, and filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml extractum Han 0.1g, adds component 1 and stirs, and bottles after ultraviolet sterilization.
For solving above-mentioned technical problem, the present invention also provides for the preparation method of a kind of Chinese medicinal external-application ointment treating talalgia, and described Chinese medicinal external-application ointment preparation process can also be:
A. take Radix Notoginseng, Herba Asari, Myrrha, Olibanum and the Radix Saposhnikoviae way of distillation and be vaporized into crystallization, pulverize dusting cover stand-by, as component 1;
B. remaining raw material Oleum Sesami is extracted, as component 2;
C. bottle after component 1, component 2 being mixed, ultraviolet sterilization.
In described step b, the raw medicinal material of above-mentioned ratio of weight and number can be added in the Oleum Sesami of 5-10 times of weight portion and soak 7-10 days, heating, big fire is boiled, and after Oleum Sesami boiling, firepower reduces, endure to pharmaceutical presentations be dark brown, internal coke yellow, pulls medicinal residues out, continues to temper by medicine oil, and be stirred continuously, refining is to beading of dripping;Plumbum preparatium is fried to vermilion, removes moisture, cross 100-120 mesh sieve and remove impurity;Plumbum preparatium is slowly added in the medicine oil refined, is stirred continuously, become the thick paste of black, be poured in cold water after the plaster that refined is the coldest, soak 5-10 days, change water every day once, releasing fire-toxin.
Traditional Chinese medical science QI and blood theory is thought, qi-blood circulating process is the material base that all histoorgans of human body are operated, QI-blood circulating regularly freely balances as expensive, if QI and blood is the most smooth will produce blood stasis, blood stasis hinders in internal, will further result in the deterioration of qi-blood circulating, cause more serious stasis of blood plug, therefore the traditional Chinese medical science is with QI and blood as guiding principle, be allowed to smooth balance by regulating qi and activating blood, can disease-relieving and physique enhancing, unsting and invigorate blood circulation.All medicines are as unguentum external, and medicine directly acts on local, permeate skin, through sick institute, promote qi and blood circulation, improve local blood and run, soften bony spur, promote that inflammation absorbs, so that remission or elimination.
Detailed description of the invention
Traditional Chinese Medicine early has research to the disease of talalgia, and Sui Dynasty famous physician Chao Yuanfang (550-630 A.D.) talalgia is called " heel is ruined ", book cloud: " heel ruined person heel neglects pain, must not also, common customs are exhaled as heel ruined." big physician's ZHU Dan-xi of one of Au element in " danxi's experiential therapy " referred to as " talalgia ", it is necessary to use the attached cream in osmanthus.
Plaster is a wonderful work of motherland's medical science, and Gu has the saying such as " reason of the external treatment i.e. reason for the treatment of by oral administration of medicines, the medicine of the external treatment i.e. medicine for the treatment of by oral administration of medicines, different person, method ear ", " it is sick that plaster can control treatment by Chinese herbs macLean-Maxwell disease, and not different from decoction is done in the proper way, and it rings vertical answering " with it.The Qing Dynasty's famous physician Xu Ling tire is said: " modern plaster used, the plaster applying a plaster for therapeutic purpose of ancients' meaning..... control inner person, or wind dispelling trembled with fear, or and QI and blood, or expectorant painful abdominal mass, or strengthening bone and muscle, its side very spirit, medicine also adds and subtracts with disease, and its cream preferably weigh thick long paste.”
Tcm syndrome differentiation and treatment, classification therapy: 1. kidney yin deficiency type: foot shin intermittent fever and talalgia, add Carapax et Plastrum Testudinis, Cortex Cinnamomi with pill of Six Ingredients.2. kidney yang deficiency syndrome: can not standing for a long time and talalgia, with eight taste balls.3. wetness type: weigh and swell, with changing bone pellet, shiguogong wine.4. multiple abscess caused by damp-phlegm type: add Fructus Chaenomelis, Bi, Radix Stephaniae Tetrandrae with Daotan Tang.5. QIXUELIANGXU type: with BUZHONG YIQI TANG, decoction of ten powerful tonics.6. blood-heat type: add the Rhizoma Anemarrhenae, Cortex Phellodendri, Radix Achyranthis Bidentatae (see " Elementary Medicine tinea pedis ") by SIWU TANG.
All medicines are as unguentum, and medicine acts on local, permeate skin, through sick institute, promote qi and blood circulation, improve local blood and run, soften bony spur, promote that inflammation absorbs, so that remission or elimination.
Traditional Chinese medical science QI and blood theory is thought, qi-blood circulating process is the material base that all histoorgans of human body are operated, QI-blood circulating regularly freely balances as expensive, if QI and blood is the most smooth will produce blood stasis, blood stasis hinders in internal, will further result in the deterioration of qi-blood circulating, cause more serious stasis of blood plug, therefore the traditional Chinese medical science is with QI and blood as guiding principle, be allowed to smooth balance by regulating qi and activating blood, can disease-relieving and physique enhancing, unsting and invigorate blood circulation.
Radix Angelicae Pubescentis, Chinese medicine name.Dry root for samphire Angelica pubescens Angelica pubescens Maxim.f.biserrata Shan et Yuan.Acrid in the mouth, hardship, slightly warm in nature.Return kidney, bladder warp.Effect expelling wind and removing dampness, arthralgia aggravated by cold pain relieving.Curing mainly for anemofrigid-damp arthralgia, pain to be washed, few the moon volt wind headache, wind and cold holds wet headache under the arm." book on Chinese herbal medicine converges and says ": Radix Angelicae Pubescentis, benefaction blood system, the medicine of the wet cold expelling of row that dispels the wind is also.The card of all sick wind, as head term can not pitching, waist knee joint can not bend and stretch, or arthralgia pain is difficult to walk, numbness need not, all wind is caused with cold, and summer-heat is with wet institute wound also;Must be warm by the toil of Radix Angelicae Pubescentis, activity QI and blood, cold expelling of dispelling is evil, therefore " herbal " speech can dissipate tinea pedis, changes renal mass, treats hernia abdominal mass, subduing inflammation, controls harmful wind hundred joint and attacks pain, the strongly fragrant headache of YIN-cold less, it is intended that this.
Fructus Psoraleae acrid in the mouth;Bitter in the mouth;Warm in nature return through kidney;Pericardium;Spleen;Stomach;Lung meridian function cures mainly: reinforcing the kidney and supporting YANG;Helping inspiration to relieve asthma;Warming spleen and stopping diarrha.Main insufficiency of kidney-YANG;Below element deficiency and cold;Chills and pain of the waist and kness;Sexual impotence essence;Frequent micturition;The enuresis;Failure of the kidney in receiving QI;Dyspnea due to deficiency is more than;Asthenia of both the spleen and kidney;Stool chronic diarrhea." Bencao Jingshu ": Fructus Psoraleae, can warming the kidney;Raw sun in the moon, the key medicine of excessive fire benefit soil is also.Its main five kinds of strain and seven kinds of impairment, the disease of lid edge impairment caused by overstrain, arise from asthenia of both the spleen and kidney more, with its can warming the kidney, mend fire with the raw-soil, then in kidney kidney-Yang be so incensed that mend and rise, then can digesting food, steam waste matter and change precise and tiny.Lung it is attributed on spleen-QI transporting the essence to the whole body, with the foster the five internal organs of honor, therefore the labor of main the five internal organs.Seven emotions hinder disease of viscera connecting with this channel.Wind cold caused by deficiency person, because yang-energy is decayed, and the most air-cooled visitor that takes advantage of a weak point in opponent's defence so that bone marrow wound loses, kidney cold essence stream, and kidney governing bones store essential substances, marrow be essence this, the gas of kidney-Yang is solid, i.e. before card see, solid itself and yang-energy life, then front card removes in vain.Man is based on essence, and married woman is based on blood, and married woman vim and vigour person, the most still man's sun kidney that declines is cold and be the disease of blood prostration QI collapse caused by exhaustion of QI of the spleen and kidney, with the kidney of man cold essence stream also.
Rhizoma Drynariae is bitter, temperature.Enter liver, kidney channel.Function cures mainly the kidney invigorating, invigorates blood circulation, hemostasis.Control suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus." property of medicine opinion ": " poison in main bone, wind blood pain, five kinds of over strain six types of severe debility disease, mouth (one make ' foot ') hands do not receives, upper heat and lower cold." " Japan hanako materia medica ": " controls malignant boil, loses rotten meat, parasite killing.″
Pheretima: Compendium of Material Medica referred to as has dredge the meridian passage, blood circulation promoting and blood stasis dispelling, prophylactic treatment cardiovascular and cerebrovascular disease effect.Pheretima salty in the mouth cold in nature.Function: heat clearing away, suppressing the hyperactive liver, Zhichuan, logical Lip river.Cure mainly high fanatical dry, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, hemiplegia etc..
Flos Carthami (Classification system: Carthamus tinctorius L.), another name: red blue flower, thorn Flos Carthami, Compositae, Flos Carthami platymiscium, dry tubular flower, orange red, floral tube is narrow carefully, and tip 5 splits, and sliver is narrow linear, flower pesticide yellow, being unified into pipe, exceed outside sliver, its central authorities have stigma to expose.Have special fragrance, mildly bitter flavor.To spend, length of a film, color be scarlet, the soft person of matter is preferred.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contribute to controlling amenorrhea, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, breast side of body twinge, traumatic injury, skin infection swell and ache curative effect.Blood circulation promoting and blood stasis dispelling, wet dissipation is had to go the effect swollen.
Radix Notoginseng is to be used as medicine with its root, and it is warm in nature, acrid in the mouth, has significant blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain effect, has " Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae) ", the good reputation of " southern part of the country SHENCAO ".Because season in Chang Chun winter two excavates, it is divided into again " spring seven " and " winter seven ".Described in Qing Dynasty's pharmaceutical texts supplementary Amplifications of the Compendium of Materia Medica: " ginseng qi-tonifying first, Radix Notoginseng enriches blood first, taste with and merit also etc., therefore claim Panax pseudoginseng, for the most precious person in Chinese medicine." become famous Chinese patent medicine " YUNNAN BAIYAO " at home and abroad and " Pien Tze Huang ", i.e. make with Radix Notoginseng for primary raw material.Cure mainly spitting of blood, spit blood, epistaxis, have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling and swelling.
Rhizoma Chuanxiong, formal name used at school: Ligusticum chuanxiong hort, cultivated plant, main product in Sichuan (Guanxian county), in Yunnan, Guizhou, the ground such as Guangxi, be grown on the climatic environment of gentleness.Being a kind of Chinese medicinal plant, be usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, the pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keeps, can go scattered, up up to top, mountain peak;Enter again blood system, descending up to the sea of blood.Blood circulation promoting and blood stasis dispelling effect is extensive, the various disease of suitable stagnation of blood stasis;Wind-expelling pain-stopping, effectiveness is favourable, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.It is the gas medicine in blood that former times people calls Rhizoma Chuanxiong, the function such as its residence of dangerous speech is pungent to be dissipated, resolving depression, sensible, pain relieving.
Caulis Spatholobi, for the another name of the various plants such as Schisandraceae, Sargentodoxaceae, Cuscutaceae, Papilionaceae.8~JIUYUE gather, be distributed in China East China, South China and the ground such as Hubei, Yunnan.Caulis Spatholobi bitter but slightly sweet taste, warm in nature, return liver, the heart, kidney channel, red complexion enters blood, and matter profit row dissipates;There is relaxing muscles and tendons to promote blood circulation, effect of nourishing blood for regulating menstruation;Cure mainly rheumatic arthralgia, numb hand and foot, quadriplegia, menoxenia, blockage of menstruation, dysmenorrhea, amenorrhea, leukopenia.The treatment waist gonalgia caused by rheumatism, rheumatic arthralgia, numb limbs and tense tendons, often and the compatibility such as Flos Carthami Radix Angelicae Pubescentis, Radix Paeoniae Rubra, Pheretima, the Radix Astragali, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae.Can be used for menoxenia, amenorrhea, dysmenorrhea, normal and Rhizoma Cyperi, the same use of Herba Leonuri.
Radix Dipsaci, has another name called Radix Dipsaci, also name Radix Dipsaci, Chinese medicine name.For the root of herbaceos perennial Radix Dipsaci, gain the name because of energy " synthetism of continuous folding ".Autumn excavates, and removes root head and fibrous root, is dried to low baking temperature half-dried, when bank up " diaphoresis " is to internal virescence, then dries." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " meridians determine in tonifying liver, bone and muscle strengthening, and only in warp, (muscles and bones) is ached, antiabortive, is suitable for controlling married woman leucorrhea, tissue regeneration promoting blood, removing blood stasis with potent drugs blood, and fall stillborn fetus, and cough-relieving is coughed hemoptysis, controls red white turbid urine.”
Herba speranskiae tuberculatae, (formal name used at school: Phryma leptostachya L.subsp.asiatica (Hara) Kitamura) is used as medicine part for plant herb.Green, dry with herb color, matter is tender, free from admixture person is preferred.It is distributed in all parts of the country.It mostly is artificial plantation.Reddish brown with stem color, without leaf, be dried, free from admixture person is preferred.Annual herb flowers, produce the nations of China and India.Property happiness sunlight, be afraid of wet, heat-resisting can not resist cold, suitable be born in loose fertile micro-sour soil earth, but the most barren-resistant.Adaptability is relatively strong, transplants and easily survives, and growth is rapidly.Seed also name Semen Impatientis, stem also name Herba speranskiae tuberculatae, all can be used as medicine, have blood circulation promoting and blood stasis dispelling, diuresis removing toxic substances, deep effect of stimulating the menstrual flow.External application mashed by fresh grass, can control the swollen pain of furuncle, insect-bite.
Radix Clematidis belongs to medicinal plants, and medical material Ji Yuan source is more, and the contained Radix Clematidis such as " Kaibao Bencao ", " Bencao Tujing ", herbal for Relief of Famines, for goatweed;The Radix Clematidis that " the southern regions of the Yunnan Province book on Chinese herbal medicine " is contained, is feverfew, and use now mostly be " China's book on Chinese herbal medicine " contained cohosh Radix Clematidis, Clematis hexapetala, northeast clematis.Domestic distributed more widely, its root and stem are used as medicine and have wind-damp dispelling, the meridian dredging, the effect of the bone stalk that disappears.In modern clinic is put into practice, its new purposes is constantly found, such as treatment cholelithiasis, calcanean spur, talalgia, the esophageal carcinoma etc..Expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, dissipate the hypochondriac lump.Curing mainly gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, knee joint cold type of pain, muscle arteries and veins contracture, joint stuffiness, tinea pedis, malaria, lump in the abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat swallow.Tang Materia Medica: waist, kidney, foot knee joint, accumulation, all cold diseases of enteral, is not recovered, the effect of clothes." Kaibao Bencao ": main all wind, logical five Tibetan of a surname, cold stagnant in removing abdomen, septum cordis expectorant water amasss for a long time, lump in the abdomen Xuan tinea air parcel, bladder place pus aversion to water, the cold pain of waist knee joint and treatment injured.
Radix Saposhnikoviae, Chinese medicine name.Another name copper rue, Hui Yun, return grass, Rhizoma Cibotii, hundred kinds.The name of a kind of medicinal herbs, herbaceos perennial, its nice and cool weather of happiness, cold-resistant, drought-resistant, main product in Hebei, Heilungkiang, Sichuan, the ground such as Inner Mongol.The Gen Kesheng of Radix Saposhnikoviae uses.Acrid in the mouth, sweet, slightly warm in nature.There are expelling pathogenic wind from the body surface, removing dampness to relieve pain, effect of relieving convulsion.
Radix Stephaniae Tetrandrae, Chinese medicine name.Dry mature fruit for samphire Fructus Foeniculi Foeniculum vuLgare Mill..Autumn fruit just ripe time tap plant, dry, lay fruit, remove impurity.Acrid in the mouth, warm in nature.Return liver,kidney,spleen, stomach warp.Radix Stephaniae Tetrandrae has dispersing cold for relieving pain, effect of regulating qi-flowing for harmonizing stomach.Salt Radix Stephaniae Tetrandrae has effect of warming the kidney dispersing cold for relieving pain.Radix Stephaniae Tetrandrae is suffered from abdominal pain for colic of cold type, the testis swelling and hanging down of either of the testes, dysmenorrhea, few abdomen cold type of pain, abdominal distention, lack of appetite and vomiting.Salt Radix Stephaniae Tetrandrae is suffered from abdominal pain for colic of cold type, the testis swelling and hanging down of either of the testes, through cold stomachache.
Olibanum, Chinese medicine name.The resin oozed out for olive subject plant Boswellia carterii Boswellia carterii Birdw. and congener Boswellia bhaurdaiiana Birdw. bark.Being divided into Somalia's Olibanum and Gum Olibanum Ethiopia, every kind of Olibanum man's cap used in ancient times again is Olibanum pearl and former Olibanum.Blood-activating and qi-promoting pain relieving, detumescence and promoting granulation.Cure mainly for obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation, lump in the abdomen stomachache, rheumatic arthralgia, muscle arteries and veins contracture, traumatic injury, carbuncle skin infection.
Myrrha, Chinese medicine name.For olive subject plant Herba Violae tree Commiphora myrrha Engl. or the dry resin of Kazakhstan Herba Violae tree Commiphora molmol Engl..It is divided into natural Myrrha and gum opoponax.It is distributed in the ground such as Somalia, Ethiopia and south, the Arabia Peninsula.There is dissipating blood stasis analgesic therapy, effect of detumescence and promoting granulation.It is usually used in obstruction of qi in the chest and cardialgia, gastralgia, dysmenorrhea amenorrhea, postpartum stagnation, abdominal mass stomachache, rheumatic arthralgia, traumatic injury, the treatment of the diseases such as carbuncle skin infection.
Radix Stephaniae Tetrandrae inducing diuresis to remove edema;Wind-expelling pain-stopping.Main edema;Dysuria;Rheumatic arthralgia;Tinea pedis swells and ache;Scabies skin ulcer swells;Hypertension etc..Bitter in the mouth;Pungent;Cold in nature;Return bladder;Lung;Spleen channel." herbal classic ": main air is trembled with fear pyrexial malaria, all epilepsys of steam, evil removing, profit defecation." not Lu ": treat edema, swelling due to wind, removes bladder heat, typhoid fever cold and heat pathogen, apoplexy hands muscle spasm of the leg and foot, stopping leak, dissipates carbuncle and dislike knot, (controlling) all copperworms skin ulcer, logical space between skin and muscles, sharp nine orifices.
Spina Gleditsiae, Chinese medicine name.Dry Spina jujubae for leguminous plant Fructus Gleditsia Gleditsia sinensis Lam..There is detumescence poison holding, evacuation of pus, effect of parasite killing.Be usually used in carbuncle from the beginning of or difficulty in discharging of pus;External treatment scabies leprosy.Elementary Medicine ": " Spina Gleditsiae, all carbuncle persons of not breaking can have one's ideas straightened out;Do not break person and can reach skin ulcer institute by priming, be all malignant boil tinea and leprosy key medicine also." Compendium of Material Medica: " Fructus Gleditsia acupuncture controls wind parasite killing, and merit is same with pod, the different ear but its sharp keen through disease is done.”
Fructus Chaenomelis cultivation of commonly seeing for viewing and admiring, fruit puckery, edible in decocting in water or dipping sugar liquid, be used as medicine to have and relieve the effect of alcohol, go expectorant, pleasant, the effect of dysentery relieving.Peel is the most smooth, not shrinkage, therefore has the title of Fructus Chaenomelis Chinesis.Fructus Chaenomelis deliciousness has dietary function concurrently, especially more has beauty functions to women.Protease contained by Fructus Chaenomelis, can compensate the secretion of pancreas and intestinal, supplements the deficiency of gastric juice, contributes to decomposing protein and starch.Fructus Chaenomelis contains carotene and abundant vitamin C, and they have the strongest oxidation resistance, help body repair tissue, eliminate noxious substance, strengthen body immunity, helps body opposing virus attack including swine flu.Effective ingredient in pawpaw fruit can improve cytophagous effect.
Caulis Sargentodoxae, another name: Caulis Sargentodoxae, Classification system: Sargentodoxa cuneata. is Lardizabalaceae, Saggentodoxa fallen leaves, bejuco;Rhizome is pharmaceutically acceptable, has dredge the meridian passage, eliminating stasis to stop pain, effect such as promoting the circulation of blood, parasite killing of regulating the flow of vital energy, cure mainly rheumatalgia, joint acid that Changes in weather causes is swollen, traumatic injury, dysmenorrhea, amenorrhea, ascarid.Also veterinary medicament can be made, effective in cure to oxen and horses food supply retail shop's Hirudo associated diseases by mistake.
Eupolyphaga Seu Steleophaga, Chinese medicine name.For Corydiidae insecticide eupolyphoge sinensis Eupolyph, aga sin, ensis Walker or the female worm dry body of Ji eupolyphoge sinensis Steleophaga Plancyi (Boleny).There is removing blood stasis, effect of reunion of fractured tendons and bones.For traumatic injury, the injury of tendon and muscle is fractured, blood stasis amenorrhea, and postpartum stagnation is suffered from abdominal pain, addiction abdominal mass mass in the abdomen.
Radix Flemingiae Philippinensis, formal name used at school: Flemingia philippinensis Merr.et Rolfe, root hyoscine, there are the effects such as expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, bone and muscle strengthening, anti-inflammatory analgetic.Expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, bone and muscle strengthening, anti-inflammatory analgetic.Miao Ethnomedicine: radical cure rheumatic ostalgia, lumbar muscle strain, hemiplegia, and chronic tracheitis, mastitis, poliomyelitis sequela, venom " Hunan indigo plant is examined ".
Herba Asari relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, sensible, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, watery nasal discharge of having a stuffy nose, allergic rhinitis, nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.Herba Asari is as medicinal plants, and Shi Zai Qin Han Shennong's Herbal, Shennong's Herbal is classified as top grade.Herba Asari root is thin, color sallow, leaf color are green, acrid in the mouth peppery fiber crops tongue.Warm in nature, slightly poisonous.GUIXIN, lung, kidney channel.Dispel the wind, cold expelling, warming the lung, Hang Shui, the effect having one's ideas straightened out.Control headche due to wind-cold, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.Additionally, Herba Asari also has anti inflammatory immunity, local anesthesia, raising metabolism, antibacterial action, also can be used for the leukopenia of Chemotherapy of Tumor Patients and caused by radiation.
Fructus Foeniculi, Chinese medicine name.Dry mature fruit for samphire Fructus Foeniculi Foeniculum vuLgare Mill..Autumn fruit just ripe time tap plant, dry, lay fruit, remove impurity.Acrid in the mouth, warm in nature.Return liver,kidney,spleen, stomach warp.Fructus Foeniculi has dispersing cold for relieving pain, effect of regulating qi-flowing for harmonizing stomach.Salt Fructus Foeniculi has effect of warming the kidney dispersing cold for relieving pain.Fructus Foeniculi is suffered from abdominal pain for colic of cold type, the testis swelling and hanging down of either of the testes, dysmenorrhea, few abdomen cold type of pain, abdominal distention, lack of appetite and vomiting.Salt Fructus Foeniculi is suffered from abdominal pain for colic of cold type, the testis swelling and hanging down of either of the testes, through cold stomachache.
Herba Lycopodii is the herb of Lycopodiaceae Lycopodium plant Lycopodium clavatum Lycopodium japonicum Thunb..Control arthralgia: Radix et Rhizoma Smilacis Ripariae five money, roadside chaste tree one or two, Radix Ilicis Pernyi one or two, Herba Siegesbeckiae five money.It is decocted in water for oral dose.(" Hunan medicine will ") meridian distribution of property and flavor: toil temperature, enters Liver Channel.Attending effectiveness: expelling wind and cold. dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral.For anemofrigid-damp arthralgia, muscle arteries and veins contracture pain carbuncle.External is controlled osteopatia sprain and is swollen and ache.
Fructus Psoraleae fruit medicine, has kidney invigorating and YANG supporting, the function of spleen reinforcing stomach invigorating, and can control the dermatosiss such as psoriasis.The property of medicine: bitter, pungent, warm.Return kidney, spleen channel.Effect kidney invigorating and YANG supporting, controlling nocturnal emission with astringent drugs reducing urination, lumbago due to renal deficiency, frequent micturition, bed-wetting, kidney leaks, warming spleen and stopping diarrha, helping inspiration to relieve asthma.
The micro-hardship of Ramulus Mori;Property flat.Wind-damp dispelling, profit joint, row aqueous vapor.Cure mainly: control anemofrigid-damp arthralgia, spasm of the limbs, beriberi edema, human body pruritus due to wind pathogen.Wind-damp dispelling;The meridian dredging;Row aqueous vapor.Main air pain of dampness syndrome;Apoplexy and hemiplegia;Edema tinea pedis;Human body pruritus due to wind pathogen.For takeing on arm, joint aches numbness." Bencao Tujing ": treat and be dried all over body pruritus due to wind pathogen, tinea pedis pathogenic wind, spasm of the limbs, upper gas, to feel dizzy, lung qi is coughed, and helps digestion;Diuresis, holds concurrently and treats xerostomia." book on Chinese herbal medicine covers bamboo fish trap ": profit breathes heavily inverse gas of coughing, detumescence poison carbuncle.
Specific embodiment 1
Radix Notoginseng 1000g, Herba Asari 1000g, Myrrha 1000g, Olibanum 1000g and the Radix Saposhnikoviae 1000g way of distillation are vaporized into crystallization, pulverize stand-by, for component 1;Other raw materials Herba Lycopodii 1000g, Spina Gleditsiae 1000g, Rhizoma Drynariae 1000g, Cortex Eucommiae 1000g, Rhizoma Corydalis 1000g, Caulis Spatholobi 1000g, Fructus Chaenomelis 1000g, Radix Clematidis 1000g, Fructus Psoraleae 1000g, Radix Dipsaci 1000g, Radix Flemingiae Philippinensis 1000g, Radix Stephaniae Tetrandrae 1000g, Rhizoma Chuanxiong 1000g, Herba speranskiae tuberculatae 1000g, Pheretima 1000g, Eupolyphaga Seu Steleophaga 1000g, Cortex Acanthopancis 1000g, Radix Angelicae Pubescentis 1000g, Caulis Sargentodoxae 1000g, Folium Artemisiae Argyi 1000g, Ramulus Mori 1000g, Fructus Foeniculi 1000g soak with ethanol, heated and boiled 3 times, each 1-2 hour, filters, and filtrate is standby;By in the filtrate suction concentrating under reduced pressure tank merging latter 3 times, being evaporated to relative density is 1.20, the extractum of temperature to 60 DEG C-70 DEG C;Become component 2, blending ingredients 1 and component 2, mediation vaseline, make unguentum.
Specific embodiment 2
According to described number by raw material Herba Lycopodii 1200g, Spina Gleditsiae 1300g, Rhizoma Drynariae 1200g, Cortex Eucommiae 1100g, Rhizoma Corydalis 1200g, Caulis Spatholobi 1200g, Fructus Chaenomelis 1300g, Radix Clematidis 1200g, Fructus Psoraleae 1200g, Radix Dipsaci 1200g, Radix Flemingiae Philippinensis 1200g, Radix Stephaniae Tetrandrae 1200g, Rhizoma Chuanxiong 1200g, Herba speranskiae tuberculatae 1200g, Pheretima 1200g, Eupolyphaga Seu Steleophaga 1200g, Cortex Acanthopancis 1200g, Radix Angelicae Pubescentis 1200g, Caulis Sargentodoxae 1200g, Folium Artemisiae Argyi 1200g, Ramulus Mori 1200g, Fructus Foeniculi 1200g, add in the Oleum Sesami of 5-10 times of weight portion and soak 7-10 days;By soaked for Oleum Sesami crude drug heating extraction, big fire is boiled, and after Oleum Sesami boiling, firepower reduces, endure to crude drug appearance be dark brown, internal coke yellow, pull medicinal residues out, continue to temper by medicine oil, and be stirred continuously, refining is to beading of dripping.Radix Notoginseng 1200g, Herba Asari 1200g, Myrrha 1200g, Olibanum 1200g and the Radix Saposhnikoviae 1200g way of distillation are distilled into crystallization, and are ground into mistake 200-300 mesh sieve after fine powder.Being put in the medicine oil tempered by the crystallization fine powder sieved, paste making agent is poured in cold water the most afterwards, soaks 5-10 days, changes water every day once, releasing fire-toxin.
Specific embodiment 3
Radix Notoginseng 1200g, Herba Asari 1200g, Myrrha 1100g, Olibanum 1200g and the Radix Saposhnikoviae 1200g way of distillation are vaporized into crystallization, pulverize stand-by, for component 1;Other raw materials Herba Lycopodii 1200g, Spina Gleditsiae 1300g, Rhizoma Drynariae 1200g, Cortex Eucommiae 1100g, Rhizoma Corydalis 1200g, Caulis Spatholobi 1200g, Fructus Chaenomelis 1300g, Radix Clematidis 1200g, Fructus Psoraleae 1200g, Radix Dipsaci 1300g, Radix Flemingiae Philippinensis 1200g, Radix Stephaniae Tetrandrae 1300g, Rhizoma Chuanxiong 1200g, Herba speranskiae tuberculatae 1200g, Pheretima 1200g, Eupolyphaga Seu Steleophaga 1200g, Cortex Acanthopancis 1200g, Radix Angelicae Pubescentis 1200g, Caulis Sargentodoxae 1200g, Folium Artemisiae Argyi 1200g, Ramulus Mori 1300g, Fructus Foeniculi 1200g, soaked and be placed in lid stainless steel cask, add 70% ethanol, quality is coarse grained 0.8-1 times, stir, moistening airtight placement more than 1 hour, make fully to expand;By bottom percolator filter plate gauze bag parcel pave after again the drug sample after moistening expansion is mixed pine do dissipate, then powder is contained with rustless steel spoon, load percolator uniformly, dress 10-12 cm thick, even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurization, medicated powder loads 2/3 eminence that must not exceed percolator;Medicated powder face upper cover rustless steel orifice plate fastens, and opens the baiting valve below percolator, and puts a container, is then slowly added into 70% ethanol;Air between medicated powder powder to be discharged, and have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open baiting valve and carry out percolation, controlling percolation speed and be generally 1000g medical material outflow per minute 2~3ml, filtrate puts into liquid container, and pours ethanol during emptying into liquid container;Percolate is merged and stands, stand for standby use;The filtrate of filtration being inserted in economic benefits and social benefits vacuum concentrator, when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.05, sets to 0~5 DEG C of deepfreezes 24 hours;The filter aid kieselguhr adding 0.3% by cold preservation liquid, filters, and filtrate is inserted in economic benefits and social benefits vacuum concentrator again, is concentrated into every 1ml crude drug amount Han 0.1g, for component 2.By component 1 and the merging of component 2, stir, make unguentum.
External used medicine of the present invention repeatedly Skin Irritation Test result
According to the requirement of DB61-267-1998 " health product Toxicological evaluation program and the method for inspection ", medicine of the present invention is carried out repeatedly Skin Irritation Test.
Tested material: the preparation of the present invention.Weigh tested material 50g to add distilled water to make 50% pastel standby.
Laboratory animal: being provided Japan's white big ear rabbit 4, male and female half and half, body weight 2.5-3.0kg by Shandong University's medical college Experimental Animal Center, primary animal (the dynamic word the 08-018th of doctor), feed resource is ibid.Animal housing's environment: temperature: 22-25 DEG C, relative humidity: 45-55%.The Animal House quality certification number: the dynamic word the 08-37th of doctor.Test method: test first 24 hours, in every rabbit back spinal column both sides cropping preserved skin, each 3cm × 6cm of unhairing scope.Only taking tested material 0.5g/, be coated on the skin of every rabbit side, smear every day once after preparation, offside all makees solvent control.Smear 14d continuously.Cropping before being coated with every day, must not injured skin, it is ensured that tested material is fully contacted with skin.Observe dermoreaction and marking every day.Off-test, takes and smears area skin and carry out histopathologic examination.
Experimental result: repeatedly Skin Irritation Test shows that the present invention the highest stimulation index of repeatedly skin irritation and pathological tissue integration are 0, according to skin irritation strength grading standard in DB61-267-1998 " health product Toxicological evaluation program and the method for inspection ", the present invention repeatedly skin irritation intensity belongs to nonirritant.
Skin anaphylactic test
According to the requirement of DB61-267-1998 " health product Toxicological evaluation program and the method for inspection ", medicine of the present invention is carried out skin anaphylactic test.
Tested material: external preparation of the present invention.Weigh tested material 10g to add distilled water to make 50% pastel standby.Positive control: 2,4-dinitro-chloro-benzenes, Xing Jin chemical plant, Beijing product, lot number 20020522.Laboratory animal: being provided Cavia porcellus 30 by Shandong University's medical college Experimental Animal Center, male and female half and half, body weight 250-300g, primary animal, feed resource is ibid.Animal housing's environment: temperature: 22-25 DEG C, relative humidity: 45-55%.The Animal House quality certification number: the dynamic word the 08-37th of doctor.Test method: test Cavia porcellus is randomly divided into three groups, often group 10, male and female half and half, respectively tested material group, negative control group and positive controls.
Sensitization contact: guinea pig back left of spine hair was removed in first 24 hours to tested material, unhairing scope about 3cm × 3cm.Only take tested material 0.2g/, be coated in depilation district on the left of back part of animal after preparation, continue 6 hours.7th day and fortnight, be repeated once with same method, and positive controls is coated with 1%DNCB, and negative control group does not deals with.Excite contact: fortnight after last is to tested material, by tested material 0.2g/ only, be coated on depilation district on the right side of guinea pig back after preparation, after 6 hours, remove tested material, at once observe anaphylaxis situation, then again observed in 1,24,48,72 hours.Positive controls is coated with 1%DNCB, and negative control group does not deals with.Observational technique is with tested material group.
Result of the test: skin anaphylactic test shows external preparation of the present invention, according to according to sensitization of skin intensity evaluation standard relevant in DB61-267-1998 " health product Toxicological evaluation program and the method for inspection ", the invention belongs to without sensitization.
Pharmacological experiment
One, microcirculation experimental technique:
1. materials and methods:
Taking 50 Kunming mouses, Shandong University's biology laboratory provides.Being randomly divided into 5 groups, often 10 (male and female half and half) of group, it is a little that matched group every Mus auris dextra is coated with normal saline;Positive controls every Mus auris dextra gives Triam-A 20mg, treatment group invention formulation (preparing by embodiment institute method 2) solubilizer hybrid injection, test component is dosage group 600mg/kg/h in low dose group 400mg/kg/h of the present invention, the present invention, high dose 800mg/kg/h of the present invention.15min pneumoretroperitoneum injects 0.1% pentobarbital sodium 0.1ml/10g anesthetized animal, subsequently tail vein injection 0.1% epinephrine 0.1mL/10g, observes mouse right ear fine motion vein bore (μm) and 0.2mm immediately2Blood capillary net number .t inspection processes experimental data.
2 results and discussion
2.1. on microcirculatory impact
Compared with matched group, tested group 1 has showed increased (P < 0.01) to mice capillary open number;Tested group 2 venule bore and capillary open number are dramatically increased (P < 0.01);Mice fine motion, vein bore and capillary open number all had increase (P < 0.01) by tested group 3;Illustrate to be improved microcirculation by reagent, have function of promoting blood circulation to disperse blood clots (table 1).
Table 1, the present invention are on mice fine motion, vein bore and the impact of capillary open number
Two, external preparation xylol of the present invention causes the impact of mice auricle swelling
Male ICR mouse 60, is randomly divided into model control group, positive controls by body weight, the present invention high, medium and low dosage group, totally 5 groups, often group 12.Senior middle school low dose group rat smear respectively this product 350,250,125mg/kg, positive controls smears ZHENGHONGHUA YOU 125mg/kg, and model group gives equal-volume normal saline, the biggest 1 time, continuous 7 days, last was administered latter 1 hour, and 50 μ l dimethylbenzene are applied to two sides before and after every mouse right ear.After 4 hours, de-neck is put to death, and cuts ears, sweeps away left and right auricle with a diameter of 8mm rustless steel punching pin, weigh, using the difference of two auricle weight as weighing the index of swelling degree, antiinflammatory action intensity represents with suppression ratio (%), carries out statistical analysis with SPSS11.5 software kit.The results are shown in Table 2.
The table 2 impact (-x ± s) on mice ear
Group | Number of animals | Swelling (mg) |
Model control group | 12 | 14.38±2.16 |
Positive controls | 12 | 4.19±0.91*** |
High dose group of the present invention | 12 | 5.57±1.73** |
Dosage group in the present invention | 12 | 6.45±1.82* |
Low dose group of the present invention | 12 | 7.76±2.55* |
Compare with model control group: * p < 0.05, * * p < 0.01, * * * p < 0.001
Test result indicate that, this product xylol causes mice auricle swelling obvious inhibiting effect, and its high dose group compares with model group pole significant difference.
Three. the impact of rat paw edema caused by Carrageenan
Take healthy rat 30, body weight 180-220g, be randomly divided into blank group, ZHENGHONGHUA YOU positive controls, spray group of the present invention.Often group 10, male and female half and half, sub-cage rearing.Positive controls and drug component of the present invention smear 0.2g other every day, blank group gives the normal saline of same dosage and smears, successive administration 7 days, it is administered latter 30 minutes in last, inflammation is only caused respectively at Rat Right metapedes plantar subcutaneous injection 1% carrageenin suspension 0.1ml/, and within 15,30,60,120,240 minutes, survey the girth of the Rat Right metapedes sole of the foot before cause is scorching after cause inflammation, and calculate swelling rate [swelling rate=(the scorching front foot sole of the foot girth of the scorching metapedes sole of the foot girth-cause of cause) scorching front foot sole of the foot girth × 100% of/cause];The results are shown in Table 3.
The impact (X ± SD) of rat paw edema caused by table 3 Carrageenan
Note: compare with matched group: * * P < 0.01;Compare with positive controls: #P < 0.05;By upper table experimental result it can be seen that medicine group of the present invention has the pharmacological action of blood stasis dispelling of preferably subsiding a swelling.
Talalgia is a kind of commonly encountered diseases, is characterized with heel swelling, numb pain, locally tenderness, difficulty in walking.Talalgia is also known as calcanean spur or heel bone hyperosteogeny.Belonging to " rheumatism involving the bone " category in Chinese medicine, pathogenic factor is many strains with old deficiency of the kidney, and wound is with to experience cold-damp relevant.Doctor trained in Western medicine typically solves this problem with operation, though there being certain curative effect, but planting destructive operation, being propped up by calcaneus posterior tibial nerve and propping up cut-out with sural nerve, have side effect in various degree or cause some complication;Chinese medicine product then because of its draw materials natural, safety good, low side effect, documents and materials are abundant, clinical efficacy is good and enjoys favor.Medicine of the present invention acts on local, permeates skin, through sick institute, promotes qi and blood circulation, improve local blood and run, soften bony spur, promote that inflammation absorbs, so that remission or elimination.Oral administration and externally of the present invention, can effectively expand peripheral vessel, improves foot's microcirculation, and blood stasis dispelling of subsiding a swelling, activating collaterals to relieve pain effect is obvious.
Clinical research
All patients are selected from the court's outpatient service in May, 2015 in May, 2014 to talalgia patient 60 example, the maleest 25 examples, female 35 example, age 46~75 years old, and average 46 years old, biped person 37 example, monopodia 23 example, meter 97 was sufficient.Patient medical history January to 6 years, average 2 years.All deficiency of the liver and kidneys: the other network of Liver and kidney and branch thereof is walked around heel, liver governing tendons, main store blood, and the raw marrow of kidney governing bones, main store essential substances, essence.Old body, deficiency of the liver and kindey, blood and essence asthenia, passages through which vital energy circulates loses and fills, then muscle is become homeless foster, and bone is become homeless master, and bone withers flaccidity of tendon and muscle, therefore when standing or walk heel ache, dull pain, weak, pain pain relieved by pressing, the alleviation of pain touched.With heel pain, increase the weight of when standing and walk, alleviate after rest as feature.The X-ray film prompting of position, calcaneus side, heel bone hyperosteogeny 34 example, normal 45 examples of X-ray film, all meet 1997 editions " traditional Chinese medical science injury of tendon and muscle " diagnostic criterias.
Therapeutic Method
Chinese medicine fumigation and washing uses externally used paste of the present invention, side's medicine composition: Herba Lycopodii 13g, Spina Gleditsiae 13g, Rhizoma Drynariae 12g, Cortex Eucommiae 12g, Rhizoma Corydalis 13g, Caulis Spatholobi 11g, Fructus Chaenomelis 12g, Radix Clematidis 12g, Fructus Psoraleae 11g, Radix Dipsaci 12g, Radix Flemingiae Philippinensis 12g, Radix Stephaniae Tetrandrae 13g, Rhizoma Chuanxiong 13g, Herba speranskiae tuberculatae 12, Radix Notoginseng 12g, Myrrha 13g, Olibanum 12g, Herba Asari 12g, Pheretima 11g, Eupolyphaga Seu Steleophaga 11g, Radix Saposhnikoviae 12g, Cortex Acanthopancis 12g, Radix Angelicae Pubescentis 12g, Caulis Sargentodoxae 13g, Folium Artemisiae Argyi 12g, Ramulus Mori 11g, Fructus Foeniculi 12g, make unguentum by embodiment 2.Every day, hot water fumigation and wash method while hot suffered from foot, each 30-50min, then spread on affected part, and every day each 1 time sooner or later, every dose of medicinal 3g, 15 days is 1 course for the treatment of.Criterion of therapeutical effect, drafts following criterion of therapeutical effect with reference to State Administration of Traditional Chinese Medicine's " disease of tcm Standardization of diagnosis and curative effect ".Curing: heel pain disappears, walking is normal;Taking a turn for the better: heel pain alleviates, walking takes a turn for the better;Invalid: heel pain is without improving.
Efficacy result
This is organized 60 examples 97 foot patients and all obtains and follow up a case by regular visits to, follow up time January.Through 1 course of therapy, wherein cure 59 foots, patient's cure rate 60.82%;Patient takes a turn for the better 21 enough;Improvement rate 21.64%, invalid 17 foots;Patient's inefficiency 17.5%;Effective percentage 82.47%.
Talalgia is one of common ailment of middle-aged and old, usually heel portion pain occurs without obvious inducement, substantially increases the weight of for its feature, to have a strong impact on the life of middle-aged and elderly people after difficulty in walking, and walk load.Talalgia name of disease is the disease named with heel portion pain.Heel portion is the major part that human body bears a heavy burden, and has following anatomical features: heel skin is position the thickest in human body, and its subcutaneous fat is fine and close and flourishing, also known as fat pad.With the presence of synovial bursa between fat and calcaneus.Sole of the foot fascia and flexor digitorum brevis are attached to calcaneal tuberosity front, and heel string is attached to the back upper place of calcaneal tuberosity in the form of sheets.
With advancing age, organism quality declines middle-aged and elderly people, and heel tissue is through the tissue dewaterings such as long-term chronic strain, fat pad, atrophy, regression;Elastic reduction, simultaneously year the age increase skeleton decalcification gradually occur, plantar aponeurosis, tense situation during the inadaptable walking for a long time such as heel string, often at calcaneus attachment, damage the most slight courage and uprightness because being not suitable with tractive to ooze out, be with the passing of time excited into ostosis hyperosteogeny and produce bony spur.In addition there is pain in the synovial membrane sensation nerves such as also may result in synovial bursae inflammation that repeatedly rubs.The traditional Chinese medical science thinks that middle-aged and elderly people kidney qi is gradually lost, and bone withers flaccidity of tendon and muscle, and QI and blood can not be moistened in foot, and exopathogen is taken advantage of the occasion numbness resistance passages through which vital energy circulates and caused pain.Surely belong to " arthromyodynia " category.Doctor trained in Western medicine typically solves this problem with operation, though there being certain curative effect, but planting destructive operation, being propped up by calcaneus posterior tibial nerve and propping up cut-out with sural nerve, have side effect in various degree or cause some complication;Chinese medicine product then because of its draw materials natural, safety good, low side effect, documents and materials are abundant, clinical efficacy is good and enjoys favor.Medicine of the present invention acts on local, permeates skin, through sick institute, promotes qi and blood circulation, improve local blood and run, soften bony spur, promote that inflammation absorbs, so that remission or elimination.
Plaster is a wonderful work of motherland's medical science, and Gu has the saying such as " reason of the external treatment i.e. reason for the treatment of by oral administration of medicines, the medicine of the external treatment i.e. medicine for the treatment of by oral administration of medicines, different person, method ear ", " it is sick that plaster can control treatment by Chinese herbs macLean-Maxwell disease, and not different from decoction is done in the proper way, and it rings vertical answering " with it.The Qing Dynasty's famous physician Xu Ling tire is said: " modern plaster used, the plaster applying a plaster for therapeutic purpose of ancients' meaning..... control inner person, or wind dispelling trembled with fear, or and QI and blood, or expectorant painful abdominal mass, or strengthening bone and muscle, its side very spirit, medicine also adds and subtracts with disease, and its cream preferably weigh thick long paste ".
Claims (10)
1. the Chinese medicinal external-application ointment treating talalgia, it is characterised in that described Chinese medicinal external-application ointment
Crude drug including following parts by weight: Herba Lycopodii 10~20 parts, Spina Gleditsiae 10~20 parts, Rhizoma Drynariae 10~
20 parts, the Cortex Eucommiae 10~20 parts, Rhizoma Corydalis 10~20 parts, Caulis Spatholobi 10~20 parts, Fructus Chaenomelis 10~20 parts,
Radix Clematidis 10~20 parts, Fructus Psoraleae 10~20 parts, Radix Dipsaci 10~20 parts, Radix Flemingiae Philippinensis 10~20 parts, Radix Stephaniae Tetrandrae
10~20 parts, Rhizoma Chuanxiong 10~20 parts, Herba speranskiae tuberculatae 10~20 parts, Radix Notoginseng 10~20 parts, Myrrha 10~20 parts,
Olibanum 10~20 parts, Herba Asari 10~20 parts, Pheretima 10~20 parts, Eupolyphaga Seu Steleophaga 10~20 parts, Radix Saposhnikoviae 10~
20 parts, Cortex Acanthopancis 10~20 parts, Radix Angelicae Pubescentis 10~20 parts, Caulis Sargentodoxae 10~20 parts, Folium Artemisiae Argyi 10~20 parts, Mulberry
10~20 parts of branch, Fructus Foeniculi 10~20 parts.
Treat the Chinese medicinal external-application ointment of talalgia the most according to claim 1, it is characterised in that described
Chinese medicinal external-application ointment also includes the crude drug of following parts by weight: Herba Lycopodii 10~15 parts, Spina Gleditsiae 10~
15 parts, Rhizoma Drynariae 10~15 parts, the Cortex Eucommiae 10~15 parts, Rhizoma Corydalis 10~15 parts, Caulis Spatholobi 10~15 parts,
Fructus Chaenomelis 10~15 parts, Radix Clematidis 10~15 parts, Fructus Psoraleae 10~15 parts, Radix Dipsaci 10~15 parts, Radix Flemingiae Philippinensis
10~15 parts, Radix Stephaniae Tetrandrae 10~15 parts, Rhizoma Chuanxiong 10~15 parts, Herba speranskiae tuberculatae 10~20 parts, Radix Notoginseng 10~20 parts,
Myrrha 10~20 parts, Olibanum 10~20 parts, Herba Asari 10~20 parts, Pheretima 10~20 parts, Eupolyphaga Seu Steleophaga 10~
20 parts, Radix Saposhnikoviae 10~20 parts, Cortex Acanthopancis 10~20 parts, Radix Angelicae Pubescentis 10~20 parts, Caulis Sargentodoxae 10~20 parts, Chinese mugwort
Leaf 10~20 parts, Ramulus Mori 10~20 parts, Fructus Foeniculi 10~20 parts.
Treat the Chinese medicinal external-application ointment of talalgia the most according to claim 1, it is characterised in that described
Chinese medicinal external-application ointment also includes the crude drug of following parts by weight: Herba Lycopodii 10~20 parts, Spina Gleditsiae 10~
20 parts, Rhizoma Drynariae 10~20 parts, the Cortex Eucommiae 10~20 parts, Rhizoma Corydalis 10~20 parts, Caulis Spatholobi 10~20 parts,
Fructus Chaenomelis 10~20 parts, Radix Clematidis 10~20 parts, Fructus Psoraleae 10~20 parts, Radix Dipsaci 10~20 parts, Radix Flemingiae Philippinensis
10~20 parts, Radix Stephaniae Tetrandrae 10~20 parts, Rhizoma Chuanxiong 10~20 parts, Herba speranskiae tuberculatae 10~15 parts, Radix Notoginseng 10~15 parts,
Myrrha 10~15 parts, Olibanum 10~15 parts, Herba Asari 10~15 parts, Pheretima 10~15 parts, Eupolyphaga Seu Steleophaga 10~
15 parts, Radix Saposhnikoviae 10~15 parts, Cortex Acanthopancis 10~15 parts, Radix Angelicae Pubescentis 10~15 parts, Caulis Sargentodoxae 10~15 parts, Chinese mugwort
Leaf 10~15 parts, Ramulus Mori 10~15 parts, Fructus Foeniculi 10~15 parts.
4. the system of the Chinese medicinal external-application ointment treating talalgia as according to any one of claims 1 to 3
Preparation Method, it is characterised in that the preparation method of described Chinese medicinal external-application ointment comprises the following steps:
A. take Radix Notoginseng, Herba Asari, Myrrha, Olibanum and the Radix Saposhnikoviae way of distillation and be vaporized into crystallization, pulverize dusting cover
Stand-by, as component 1.
B. the extraction of surplus stock medicinal alcohol is taken, as component 2;
C. by stripped for ethanol medicinal residues soak by water 2 times, concentrated extracting solution is merged, as component 3;
D. by 2-in-1 for component 1 component and be condensed into extractum, add component 1 and stir bottling.
Treat the preparation method of the Chinese medicinal external-application ointment of talalgia the most according to claim 4, its feature
It is, in described step a, first by crude drug Radix Notoginseng, Herba Asari, Myrrha, Olibanum and Radix Saposhnikoviae steam
Method is distilled, and obtains crystal, then pulverizes, and crosses 100-120 mesh sieve, standby as component 1.
Treat the preparation method of the Chinese medicinal external-application ointment of talalgia the most according to claim 4, its feature
It is, in described step b, remaining crude drug is shredded, soaked and be placed in lid stainless steel cask,
Adding 70% ethanol, quality is coarse grained 0.8-1 times, stirs, moistening airtight placement more than 1 hour,
Make fully to expand;Filter plate gauze bag bottom percolator is wrapped up after paving again by the medicine after moistening expansion
Sample is mixed pine and is done to dissipate, and then contains powder with rustless steel spoon, loads percolator uniformly, fills 10-12 cm thick,
Even by T-bar pressure, then press aforesaid operations, loading in layer, suitably pressurize, medicated powder must not load
Exceed 2/3 eminence of percolator;Medicated powder face upper cover rustless steel orifice plate fastens, and opens the blowing below percolator
Valve, and put a container, then it is slowly added into 70% ethanol;Air between medicated powder powder to be discharged,
And have ethanol to flow out about about 20L, close baiting valve, cover cylinder of filtering, dipping 24 hours, then open
Material valve carries out percolation, controls percolation speed and is generally 1000g medical material outflow per minute 2~3ml, and filtrate is put
Enter in liquid container, and pour ethanol during emptying into liquid container;Percolate is merged and stands, stand standby
With, as component 2.
Treat the preparation method of the Chinese medicinal external-application ointment of talalgia the most according to claim 4, its feature
It is, in described step c, above-mentioned stripped raw material residue is put in 10 times amount water, soak 1-2 little
Time, heating extraction 2 times, each 1-2 hour, remove supernatant, united extraction liquid, 100-120 mesh filters,
The ultrafiltration post ultrafiltration that molecular weight is 5000-10000 through damming again, ultrafiltrate concentrating under reduced pressure relative density is 80
DEG C time 1.05 filtrate, as component 3.
Treat the preparation method of the Chinese medicinal external-application ointment of talalgia the most according to claim 4, its feature
It is, in described step d, component 2 is merged with component 3, put in economic benefits and social benefits vacuum concentrator and mix, first
Concentrating the filtrate to relative density when 80 DEG C is the concentrated solution of 1.32, sets to 0~5 DEG C of deepfreezes 24 hours;
The filter aid kieselguhr adding 0.3% by cold preservation liquid, filters, and filtrate is inserted in economic benefits and social benefits vacuum concentrator again, dense
It is reduced to every 1ml extractum Han 0.1g, adds component 1 and stir, bottle after ultraviolet sterilization.
9. the system of the Chinese medicinal external-application ointment treating talalgia as according to any one of claims 1 to 3
Preparation Method, it is characterised in that described Chinese medicinal external-application ointment preparation process can also be:
A. take Radix Notoginseng, Herba Asari, Myrrha, Olibanum and the Radix Saposhnikoviae way of distillation and be vaporized into crystallization, pulverize dusting cover
Stand-by, as component 1;
B. remaining raw material Oleum Sesami is extracted, as component 2;
C. bottle after component 1, component 2 being mixed, ultraviolet sterilization.
Treat the preparation method of talalgia Chinese medicinal external-application ointment, its feature the most according to claim 9
It is, in described step b, the raw medicinal material of above-mentioned ratio of weight and number is added the Oleum Sesami of 5-10 times of weight portion
Middle immersion 7-10 days, heats, and big fire is boiled, and after Oleum Sesami boiling, firepower reduces, and endures to pharmaceutical presentations in deeply
Brown, internal coke yellow, to pull medicinal residues out, continue to temper by medicine oil, and be stirred continuously, refining is to dripping into
Pearl;Plumbum preparatium is fried to vermilion, removes moisture, cross 100-120 mesh sieve and remove impurity;Plumbum preparatium is slowly added
Enter in the medicine oil refined, be stirred continuously, become the thick paste of black, be poured in cold water after the plaster that refined is the coldest,
Soak 5-10 days, change water every day once, releasing fire-toxin.
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN114470049A (en) * | 2022-02-24 | 2022-05-13 | 重庆市垫江县人民医院 | Plaster for treating blood stasis arthralgia and preparation and use methods thereof |
CN116115696A (en) * | 2023-04-07 | 2023-05-16 | 中国人民解放军空军军医大学 | Traditional Chinese medicine composition for improving cold Xi Fu capacity of organism and preparation method and application thereof |
CN116173161A (en) * | 2021-12-09 | 2023-05-30 | 萨仁 | Traditional Chinese medicine composition for treating spleen-kidney yang deficiency type foot bone pain and preparation method thereof |
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CN103751310A (en) * | 2013-12-31 | 2014-04-30 | 青岛恒波仪器有限公司 | External traditional Chinese medicinal preparation for treating fasciitis and preparation method thereof |
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2016
- 2016-07-12 CN CN201610548526.2A patent/CN105998246A/en active Pending
Patent Citations (1)
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CN103751310A (en) * | 2013-12-31 | 2014-04-30 | 青岛恒波仪器有限公司 | External traditional Chinese medicinal preparation for treating fasciitis and preparation method thereof |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN116173161A (en) * | 2021-12-09 | 2023-05-30 | 萨仁 | Traditional Chinese medicine composition for treating spleen-kidney yang deficiency type foot bone pain and preparation method thereof |
CN116173161B (en) * | 2021-12-09 | 2024-05-28 | 萨仁 | Traditional Chinese medicine composition for treating spleen-kidney yang deficiency type foot bone pain and preparation method thereof |
CN114470049A (en) * | 2022-02-24 | 2022-05-13 | 重庆市垫江县人民医院 | Plaster for treating blood stasis arthralgia and preparation and use methods thereof |
CN116115696A (en) * | 2023-04-07 | 2023-05-16 | 中国人民解放军空军军医大学 | Traditional Chinese medicine composition for improving cold Xi Fu capacity of organism and preparation method and application thereof |
CN116115696B (en) * | 2023-04-07 | 2023-12-12 | 中国人民解放军空军军医大学 | Traditional Chinese medicine composition for improving cold Xi Fu capacity of organism and preparation method and application thereof |
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